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https://www.readbyqxmd.com/read/29230292/multiple-steroid-and-thyroid-hormones-detected-in-baleen-from-eight-whale-species
#1
Kathleen E Hunt, Nadine S Lysiak, Jooke Robbins, Michael J Moore, Rosemary E Seton, Leigh Torres, C Loren Buck
Recent studies have demonstrated that some hormones are present in baleen powder from bowhead (Balaena mysticetus) and North Atlantic right (Eubalaena glacialis) whales. To test the potential generalizability of this technique for studies of stress and reproduction in large whales, we sought to determine whether all major classes of steroid and thyroid hormones are detectable in baleen, and whether these hormones are detectable in other mysticetes. Powdered baleen samples were recovered from single specimens of North Atlantic right, bowhead, blue (Balaenoptera [B...
2017: Conservation Physiology
https://www.readbyqxmd.com/read/29230010/serotype-and-virulence-genes-of-klebsiella-pneumoniae-isolated-from-mink-and-its-pathogenesis-in-mice-and-mink
#2
Wang Jian-Li, Shang Yuan-Yuan, Guo Shou-Yu, Diao Fei-Fei, Yu Jia-Yu, Wei Xue-Hua, Zhao Yong-Feng, Jiang Shi-Jin, Xie Zhi-Jing
In the study, 15 K. pneumoniae strains were isolated from the mink experiencing respiratory distress in mideastern Shandong province, China, and the prevalence of K. pneumoniae in the sampled mink was 11.9% (15/126). Fourteen (93.33%) of the 15 K. pneumoniae isolates were identified as serotype K2 and hypermucoviscosity phenotype. The 12 virulence-associated genes of the K. pneumoniae isolates were tested. The prevalence of the wabG gene for the isolates were 100% (15/15), the ureA gene 100% (15/15), the rmpA gene 93...
December 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29202888/octreotide-for-the-treatment-of-intentional-insulin-aspart-overdose-in-a-non-diabetic-patient
#3
Catherine M Dewaal, Eric McGillis, Matt Mink, Scott Lucyk
Intentional insulin overdose may lead to severe and refractory hypoglycemia. Exogenous dextrose administration is the mainstay of therapy for these patients and is effective in most cases. However, in patients with a functional pancreas, exogenous dextrose administration may precipitate endogenous insulin release leading to rebound hypoglycemia. We describe a case report of a 41-year-old woman who injected 300 units of insulin aspart with suicidal intent. Her initial blood glucose was 2.3 mmol/L (41 mg/dL)...
December 5, 2017: CJEM
https://www.readbyqxmd.com/read/29201280/a-network-approach-to-examining-injury-severity-in-pediatric-tbi
#4
Emily L Dennis, Faisal Rashid, Neda Jahanshad, Talin Babikian, Richard Mink, Christopher Babbitt, Jeffrey Johnson, Christopher C Giza, Robert F Asarnow, Paul M Thompson
Traumatic brain injury (TBI) is the leading cause of death and disability in children, and can lead to long lasting functional impairment. Many factors influence outcome, but imaging studies examining effects of individual variables are limited by sample size. Roughly 20-40% of hospitalized TBI patients experience seizures, but not all of these patients go on to develop a recurrent seizure disorder. Here we examined differences in structural network connectivity in pediatric patients who had sustained a moderate-severe TBI (msTBI)...
2017: Proceedings of the IEEE International Symposium on Biomedical Imaging: from Nano to Macro
https://www.readbyqxmd.com/read/29200830/notoginsenoside-r1-attenuates-high-glucose-induced-endothelial-damage-in-rat-retinal-capillary-endothelial-cells-by-modulating-the-intracellular-redox-state
#5
Chunlan Fan, Yuan Qiao, Minke Tang
The aim of this study was to examine whether Notoginsenoside R1 (NR1) attenuates high glucose-induced cell damage in rat retinal capillary endothelial cells (RCECs) and to explore the mechanisms involved. The exposure of rat RCECs to high concentration of glucose (30 mM) for 72 h led to significant cytotoxicity, including decreased cell viability, reduced mitochondrial DNA copy number, increased lactate dehydrogenase release and elevated apoptosis. NR1, when present in the culture medium, markedly attenuated the high glucose-induced cytotoxicity in rat RCECs...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/29177580/molecular-detection-and-genetic-characterizations-of-cryptosporidium-spp-in-farmed-foxes-minks-and-raccoon-dogs-in-northeastern-china
#6
Ziyin Yang, Wei Zhao, Jianguang Wang, Guangxu Ren, Weizhe Zhang, Aiqin Liu
Cryptosporidium spp. are common intestinal protozoa causing diarrhea in humans and a variety of animal species. With the recent development of fur industry, a large number of fur animals are farmed worldwide, especially in China. The existence of identical Cryptosporidium species/genotypes in humans and fur animals suggests zoonotic potential. In order to assess the presence of zoonotic Cryptosporidium species and/or genotypes in farmed fur animals, 367 fecal specimens were collected from 213 foxes, 114 minks and 40 raccoon dogs farmed in Heilongjiang, Jilin, and Liaoning provinces, northeastern China, during the period from June 2014 to October 2016...
November 25, 2017: Parasitology Research
https://www.readbyqxmd.com/read/29174533/impact-of-declining-renal-function-on-outcomes-in-pulmonary-arterial-hypertension-a-reveal-registry-analysis
#7
Murali M Chakinala, Daniel W Coyne, Raymond L Benza, Adaani E Frost, Michael D McGoon, Brian K Hartline, Robert P Frantz, Mona Selej, Carol Zhao, David R Mink, Harrison W Farber
BACKGROUND: Renal dysfunction is associated with abnormal cardiopulmonary hemodynamics, in-hospital death and poor survival in patients with pulmonary arterial hypertension (PAH), and thus it may be a prognostic biomarker. In our analysis we assess the relationship between change in estimated glomerular filtration rate (eGFR) and outcomes in PAH patients in the Registry to Evaluate Early and Long-term PAH Disease Management (REVEAL). METHODS: Overall 2,368 patients were classified into chronic kidney disease (CKD) stages based on baseline eGFR: normal or Stages 1 or 2 (n = 1,699); Stage 3a (n = 399); Stage 3b (n = 196); and Stages 4 or 5 (n = 74)...
November 6, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29166950/global-phylogenetic-analysis-of-contemporary-aleutian-mink-disease-viruses-amdvs
#8
P Ryt-Hansen, E E Hagberg, M Chriél, T Struve, A G Pedersen, L E Larsen, C K Hjulsager
BACKGROUND: Aleutian mink disease has major economic consequences on the mink farming industry worldwide, as it causes a disease that affects both the fur quality and the health and welfare of the mink. The virus causing this disease is a single-stranded DNA virus of the genus Amdoparvovirus belonging to the family of Parvoviridae. In Denmark, infection with AMDV has largely been restricted to a region in the northern part of the country since 2001, affecting only 5% of the total Danish mink farms...
November 22, 2017: Virology Journal
https://www.readbyqxmd.com/read/29165334/development-and-validation-of-an-on-line-water-toxicity-sensor-with-immobilized-luminescent-bacteria-for-on-line-surface-water-monitoring
#9
Marjolijn Woutersen, Bram van der Gaag, Afua Abrafi Boakye, Jan Mink, Robert S Marks, Arco J Wagenvoort, Henk A M Ketelaars, Bram Brouwer, Minne B Heringa
Surface water used for drinking water production is frequently monitored in The Netherlands using whole organism biomonitors, with for example Daphnia magna or Dreissena mussels, which respond to changes in the water quality. However, not all human-relevant toxic compounds can be detected by these biomonitors. Therefore, a new on-line biosensor has been developed, containing immobilized genetically modified bacteria, which respond to genotoxicity in the water by emitting luminescence. The performance of this sensor was tested under laboratory conditions, as well as under field conditions at a monitoring station along the river Meuse in The Netherlands...
November 22, 2017: Sensors
https://www.readbyqxmd.com/read/29150892/expanding-the-neurodevelopmental-phenotype-of-pura-syndrome
#10
Bo Hoon Lee, Margot R F Reijnders, Oluwatobi Abubakare, Emily Tuttle, Brynn Lape, Kelly Q Minks, Christopher Stodgell, Loisa Bennetto, Jennifer Kwon, Chin-To Fong, Karen W Gripp, Eric D Marsh, Wendy E Smith, Ahm M Huq, Stephanie A Coury, Wen-Hann Tan, Orestes Solis, Rupal I Mehta, Richard J Leventer, Diana Baralle, David Hunt, Alex R Paciorkowski
PURA syndrome is a recently described developmental encephalopathy presenting with neonatal hypotonia, feeding difficulties, global developmental delay, severe intellectual disability, and frequent apnea and epilepsy. We describe 18 new individuals with heterozygous sequence variations in PURA. A neuromotor disorder starting with neonatal hyptonia, but ultimately allowing delayed progression to walking, was present in nearly all individuals. Congenital apnea was present in 56% during infancy, but all cases in this cohort resolved during the first year of life...
November 17, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/29145610/transition-to-an-aquatic-habitat-permitted-the-repeated-loss-of-the-pleiotropic-klk8-gene-in-mammals
#11
Nikolai Hecker, Virag Sharma, Michael Hiller
KLK8 (also called neuropsin) is a serine protease that plays distinct roles in the skin and hippocampus. In the skin, KLK8 influences keratinocyte proliferation and desquamation, and activates antimicrobial peptides in sweat. In the hippocampus, KLK8 affects memory acquisition. Here, we examined the evolution of KLK8 in mammals and discovered that, out of 70 placental mammals, KLK8 is exclusively lost in three independent fully-aquatic lineages, comprising dolphin, killer whale, minke whale and manatee. In addition, while the sperm whale has an intact KLK8 reading frame, the gene evolves neutrally in this species...
November 14, 2017: Genome Biology and Evolution
https://www.readbyqxmd.com/read/29141680/applying-a-community-based-participatory-research-approach-to-improve-access-to-healthcare-for-eritrean-asylum-seekers-in-israel-a-pilot-study
#12
Nora Gottlieb, Tomer Weinstein, Jonah Mink, Habtom M Ghebrezghiabher, Zebib Sultan, Rachel Reichlin
BACKGROUND: Israel hosts approximately 50,000 asylum seekers, most of them from Eritrea. Exclusive policies restrict their access to healthcare. In 2013, local activists partnered with Eritrean asylum seekers to assess health needs as well as willingness to pay for health insurance among the Eritrean communities. This initiative was meant as a step towards jointly advocating access to Israel's public healthcare system and towards strengthening collective efficacy among the asylum-seeking communities, as well as a first attempt to apply a community-based participatory research (CBPR) approach to migrant health research in Israel...
November 15, 2017: Israel Journal of Health Policy Research
https://www.readbyqxmd.com/read/29135829/chikungunya-virus-infections-among-infants-who-classification-not-applicable
#13
Veronique van Keulen, Minke Huibers, Meindert Manshande, Michaël Boele van Hensbroek, Linda van Rooij
Chikungunya virus (ChikV) caused an epidemic on Curaçao in 2014-2015. Infants are highly at risk for clinical syndromes as sepsis-like illness and central nervous system disease. Clinical recognition is important if laboratory test, polymerase chain reaction (PCR) and enzyme-linked immunosorbent assay (ELISA), are not available. The World Health Organization (WHO) created criteria for identification of probable ChikV. None of the studied infants met these criteria. We believe the WHO suggested criteria should be modified for infants...
November 11, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29122866/genome-sequence-of-a-porcine-bocavirus-detected-in-feces-of-domestic-minks-in-china
#14
Yan Wang, Jing Zhao, Min Zheng, Zhijian Liu, Jiaqi Yuan, Jieji Zhao, Quan Shen, Zhaobin Fan, Lili Jiang, Shixing Yang
We report here the genome sequence of porcine bocavirus strain PBov-JZ08, which was isolated from mink feces in China. Sequence analysis implied that PBov-JZ08 clustered with three porcine bocaviruses.
November 9, 2017: Genome Announcements
https://www.readbyqxmd.com/read/29118465/antioxidant-and-anti-inflammatory-activities-in-extracts-from-minke-whale-balaenoptera-acutorostrata-blubber
#15
Mari Johannessen Walquist, Svein Kristian Stormo, Ida-Johanne Jensen, Bjarne Østerud, Karl-Erik Eilertsen
Intake of long-chain omega-3 polyunsaturated fatty acids (LC-n3-PUFA) is commonly recognized to reduce cardiovascular disease (CVD). In previous studies, cold-pressed whale oil (CWO) and cod liver oil (CLO) were given as a dietary supplement to healthy volunteers. Even though CWO contains less than half the amount of LC-n3-PUFA of CLO, CWO supplement resulted in beneficial effects on anti-inflammatory and CVD risk markers compared to CLO. In the present study, we prepared virtually lipid-free extracts from CWO and CLO and evaluated the antioxidative capacity (AOC) and anti-inflammatory effects...
2017: Mediators of Inflammation
https://www.readbyqxmd.com/read/29109430/the-first-draft-reference-genome-of-the-american-mink-neovison-vison
#16
Zexi Cai, Bent Petersen, Goutam Sahana, Lone B Madsen, Knud Larsen, Bo Thomsen, Christian Bendixen, Mogens Sandø Lund, Bernt Guldbrandtsen, Frank Panitz
The American mink (Neovison vison) is a semiaquatic species of mustelid native to North America. It's an important animal for the fur industry. Many efforts have been made to locate genes influencing fur quality and color, but this search has been impeded by the lack of a reference genome. Here we present the first draft genome of mink. In our study, two mink individuals were sequenced by Illumina sequencing with 797 Gb sequence generated. Assembly yielded 7,175 scaffolds with an N50 of 6.3 Mb and length of 2...
November 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29109138/author-response-education-research-positive-effect-of-scheduled-faculty-modeling-on-clerkship-student-bedside-skills-exposure-and-learning
#17
Robert Thompson Stone, Trenton Tollefson, Ronald Epstein, Ralph F Jozefowicz, Jonathan W Mink
No abstract text is available yet for this article.
November 7, 2017: Neurology
https://www.readbyqxmd.com/read/29106961/immunological-analysis-of-food-proteins-using-high-performance-thin-layer-chromatography-immunostaining
#18
Lena Morschheuser, Kathrin Mink, Ramona Horst, Constanze Kallinich, Sascha Rohn
The chromatographic analysis of intact proteins is still challenging, especially when biological functions as antigenicity of proteins or peptides are in the focus. Traditional immunoassays provide information about the entirety of antigenic proteins/peptides, e.g., in ELISA assays. On the other hand, when focusing on the investigation of (cross) reactivity of antibodies, Western blot following gel-electrophoresis represents the method of choice. However, gel-electrophoresis is limited by the molecular weight and therefore, not suitable for peptides ≤3kDa or proteins ≥250kDa...
October 20, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29105815/mate-choice-screening-in-captive-solitary-carnivores-the-role-of-male-behavior-and-cues-on-mate-preference-and-paternity-in-females-of-a-model-species-american-mink-neovison-vison
#19
Christina Lehmkuhl Noer, Thorsten Johannes Skovbjerg Balsby, Razvan Anistoroaei, Mikkel Stelvig, Torben Dabelsteen
Mate choice studies suggest that choosy females benefit from increased fecundity, litter size, and offspring survival. Thus, providing females with the opportunity to choose among potential mates, deemed genetically suitable based on studbook data, might improve breeding management in production and zoo animals and thereby the sustainability of captive populations. Investigating mate preference via odor from potential mates before animal transfer is a proposed strategy for incorporating mate choice into breeding management...
November 5, 2017: Zoo Biology
https://www.readbyqxmd.com/read/29101638/mercury-concentrations-in-bats-chiroptera-from-a-gold-mining-area-in-the-peruvian-amazon
#20
Mónica Moreno-Brush, Alejandro Portillo, Stefan Dominik Brändel, Ilse Storch, Marco Tschapka, Harald Biester
In the southeastern Peruvian Amazon, artisanal and small-scale gold mining (ASGM) is estimated to have released up to 300 tonnes of mercury (Hg) to the environment between 1995 and 2007 alone, and is claimed to be responsible for Hg concentrations above international thresholds for aquatic wildlife species. Here, we examined whether Hg concentrations in bat populations are potentially related to regional ASGM-Hg releases. We determined Hg concentrations in the fur of bats collected at three different distances from the major ASGM areas in Peru...
November 3, 2017: Ecotoxicology
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