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Fournier's gangrene

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https://www.readbyqxmd.com/read/29770194/clinical-utility-of-hyperbaric-oxygen-therapy-in-genitourinary-medicine
#1
REVIEW
Jason Gandhi, Omar Seyam, Noel L Smith, Gunjan Joshi, Sohrab Vatsia, Sardar Ali Khan
Hyperbaric oxygen therapy (HBOT) is a medical technique which delivers oxygen at ambient pressures to increase the amount of dissolved oxygen in the blood and oxygen distribution to tissues. There are several beneficial properties of HBOT concomitant with elevated oxygen distribution in tissue including anti-inflammation, angiogenesis through vascular endothelial growth factor proliferation, augmented fibroblast activity through fibroblast growth factor proliferation, tissue and wound repair, enhancement of lymphocyte and macrophage activity, increased male testosterone secretion, and bactericidal activity...
January 2018: Medical Gas Research
https://www.readbyqxmd.com/read/29756051/penile-calciphylaxis-in-a-patient-with-end-stage-renal-disease-a-case-report-and-review-of-the-literature
#2
Ti-Yuan Yang, Tao-Yeuan Wang, Marcelo Chen, Fang-Ju Sun, Allen W Chiu, Yu-Hsin Chen
Penile calciphylaxis is a rare cause of penile gangrene that presents in patients with end-stage renal disease. The rates of comorbidity and mortality of penile calciphylaxis are extremely high. Unlike other penile gangrene, such as Fournier's gangrene, the benefit of aggressive surgical therapy is controversial. Here we present a case of penile calciphylaxis in a 43-year-old man with end-stage renal disease on hemodialysis. He received total penectomy but died due to multisystem complications 2 weeks after surgery...
2018: Open Medicine (Warsaw, Poland)
https://www.readbyqxmd.com/read/29745916/fournier-s-gangrene-a-rare-complication-of-diabetes-mellitus-case-report
#3
Sh Muharremi
The presented case reports on 54-years old patient with T2 Diabetes mellitus who, due to hypoglycemic episodes on Insulin therapy, was treated with oral anti-hyperglycemic medications. Patient was on hemodialysis due to the stage 5 chronic kidney failure and had various comorbid conditions: arterial hypertension, history of acute myocardial infarction, dilative cardiomyopathy, amaurosis and peripheral neuropathy. Besides his complicated medical history, patient developed an early stage of Fournier's gangrene...
April 2018: Georgian Medical News
https://www.readbyqxmd.com/read/29628671/scrotal-reconstruction-with-integra-following-necrotizing-fasciitis
#4
Briar L Dent, Anant Dinesh, Khuram Khan, Ryan Engdahl
Scrotal loss from Fournier's gangrene can be a devastating injury with esthetic and functional consequences. Local reconstructive options can be limited by the presence of infection or the loss of neighboring tissue from debridement. IntegraTM bilayer matrix wound dressing is a well-established reconstructive modality, but only one report exists of its use in scrotal reconstruction and this was not in the setting of Fournier's gangrene. We report the successful use of Integra and a subsequent split-thickness skin graft for reconstruction of the anterior scrotum and coverage of the exposed testes in a 43-year-old man who developed Group A Streptococcus necrotizing fasciitis of his right lower extremity, groin, and scrotum requiring serial operative debridements...
January 2018: Journal of Emergencies, Trauma, and Shock
https://www.readbyqxmd.com/read/29619495/fournier-s-gangrene-in-an-obese-female-in-third-trimester-of-pregnancy
#5
Saqer Althunayyan, Evangelos Karamitosos
Fournier gangrene is a rapidly progressive necrotizing fasciitis of the perianal and genitourinary area. Although typically affects men, we present here a rare disease founding in a pregnant woman. An obese 36-year-old female patient in her third trimester of pregnancy presented with a history of perianal pain and swelling. She was subsequently diagnosed with Fournier gangrene and underwent emergency cesarean section with a surgical debridement. The key to successful outcomes in such a complicated presentation of Fournier gangrene includes a high index of suspicion, fluid resuscitation, rapid administration of broad-spectrum antibiotics, and an early interdisciplinary approach by multiple teams...
April 2018: Saudi Medical Journal
https://www.readbyqxmd.com/read/29587650/biopsy-proven-vancomycin-induced-acute-kidney-injury-a-case-report-and-literature-review
#6
Anri Sawada, Kunio Kawanishi, Shohei Morikawa, Toshihiro Nakano, Mio Kodama, Mitihiro Mitobe, Sekiko Taneda, Junki Koike, Mamiko Ohara, Yoji Nagashima, Kosaku Nitta, Takahiro Mochizuki
BACKGROUND: Vancomycin is the first-line antibiotic for methicillin-resistant Staphylococcus aureus and coagulase-negative strains. The risk of vancomycin-induced acute kidney injury increases with plasma vancomycin levels. Vancomycin-induced acute kidney injury is histologically characterized by acute interstitial nephritis and/or acute tubular necrosis. However, only 12 biopsy-proven cases of vancomycin-induced acute kidney injury have been reported so far, as renal biopsy is rarely performed for such cases...
March 27, 2018: BMC Nephrology
https://www.readbyqxmd.com/read/29507738/fournier-gangrene-in-a-patient-receiving-chemo-radiation-for-rectal-cancer
#7
Maria Pittaka, Chrysanthos Georgiou, Petros Polyviou, Pantelis Kountourakis, Panayiotis Loizou, Ifigenia Constantinou, Demetris Andreopoulos, Vassilios P Vassiliou
We herein present a case of a 24-year-old patient with a cT4N+ rectal cancer who developed Fournier's gangrene (FG) 1 week after the completion of preoperative chemoradiotherapy. The patient was promptly referred to the surgical department where she was treated with antibiotics and repeated surgical debridement. FG is a rare and life-threatening situation that needs to be managed aggressively with no delay. The clinical image above is unique and characteristic of this clinical entity.
February 2018: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29479450/fournier-gangrene-a-rare-case-of-necrotizing-fasciitis-of-the-entire-right-hemi-pelvis-in-a-diabetic-female
#8
Gregory M Taylor, David V Hess
Fournier's gangrene, a rare polymicrobial infection that affects the genitals and perineum, can present as an insidious onset to a rapid and fulminant course. Early recognition, diagnosis, initiation of broad-spectrum antibiotics and prompt surgical treatment remain the foundation of management. If treatment is not initiated aggressively, the patient will likely rapidly deteriorate, leading to organ failure and death. We present the case of a 58-year-old diabetic female presenting febrile, hypoxic, with severe respiratory distress and evidence of septic shock, found to have necrotizing fasciitis of the entire right hemi-pelvis...
February 2018: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29464174/suture-technique-to-prevent-air-leakage-during-negative-pressure-wound-therapy-in-fournier-gangrene
#9
Feng-Shu Chang, Chieh Chou, Chuan-Yu Hu, Shu-Hung Huang
Background: The use of negative-pressure wound therapy (NPWT) for Fournier gangrene management is well documented; however, it is difficult to fixate GranuFoam dressings and maintain an airtight seal over the perineum area. We developed a simple method to facilitate GranuFoam fixation and improve airtight sealing. Methods: The Fournier's gangrene severity index (FGSI) score less than 9 was collected in from January 2015 to October 2016. All 13 patients underwent fasciotomy, and NPWT was applied directly on fasciotomy wounds after the debridement of infected tissue...
January 2018: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/29451646/profile-of-patients-with-fournier-s-gangrene-and-their-clinical-evolution
#10
Djoney Rafael Dos-Santos, Ulisses Luiz Tasca Roman, André Pereira Westphalen, Keli Lovison, Fernando Antonio C Spencer Neto
OBJECTIVE: to analyze the profile of patients with Fournier's gangrene treated in a public tertiary hospital in western Paraná State. METHODS: we conducted a cross-sectional, retrospective and descriptive study of patients with Fournier's gangrene treated between January 2012 and November 2016. RESULTS: there were 40 patients with Fournier's gangrene treated in the period, 29 (72.5%) men and 11 (27.5%) women. The mean age was 51.7±16.3 years...
2018: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/29451644/scrotal-reconstruction-with-superomedial-fasciocutaneous-thigh-flap
#11
Daniel Francisco Mello, Americo Helene Júnior
OBJECTIVE: to describe the use of a superomedial fasciocutaneous thigh flap for scrotal reconstruction in open areas secondary to the surgical treatment of perineal necrotizing fasciitis (Fournier's gangrene). METHODS: retrospective analysis of cases treated at the Plastic Surgery Service of Santa Casa de Misericórdia, São Paulo, from 2009 to 2015. RESULTS: fifteen patients underwent scrotal reconstruction using the proposed flap. The mean age was 48...
2018: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/29428033/definitive-wound-closure-techniques-in-fournier-s-gangrene
#12
Margaret Lauerman, Olga Kolesnik, Habeeba Park, Laura S Buchanan, William Chiu, Ronald B Tesoriero, Deborah Stein, Thomas Scalea, Sharon Henry
Necrotizing soft tissue infection of the perineum, or Fournier's gangrene (FG), is a morbid and mortal diagnosis. Despite the severity of FG, the optimal definitive wound closure strategy is unknown, as are long-term wound outcomes. A retrospective review was performed over a 3-year period at a single trauma center. Patients were managed according to our institutional approach focusing on primary wound closure and secondary intention healing in residual wounds. Overall 168 patients were included. Complete primary wound closure was accomplished in 39...
January 1, 2018: American Surgeon
https://www.readbyqxmd.com/read/29423355/coverage-of-the-scrotum-after-fournier-s-gangrene
#13
Ahmed Hassan El-Sabbagh
Background: Fournier's gangrene is a necrotizing fasciitis caused by mixed aerobic and anaerobic bacteria and results in loss of skin and subcutaneous tissue in the perineal area. Coverage of testis varies from closure of the defect primarily, burying inside the thigh, using the remnants of the scrotum for tissue expansion and coverage by flaps. In this manuscript, scrotal advancement flaps and pudendal thigh flaps were used for coverage of the testis unilaterally or bilaterally according to the size of the defect following Fournier gangrene...
2018: GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW
https://www.readbyqxmd.com/read/29406297/sacral-pressure-ulcer-induced-fournier-s-gangrene-extending-to-the-retroperitoneum-a-case-report
#14
Kiyoko Fukui, Masaki Fujioka, Satoko Ishiyama
INTRODUCTION: Fournier's gangrene (FG) is a type of necrotizing fasciitis of the perineum and scrotum that is characterized by very rapid progression. Sacral pressure ulcers are one of the causes of FG. CASE REPORT: An 85-year-old man was referred to the National Hospital Organization Nagasaki Medical Center (Ohmura City, Japan) with a diagnosis of FG extending to the retroperitoneum caused by a sacral pressure ulcer. Immediate debridement was performed; however, it was not possible to remove all necrotic tissue from the pelvis...
January 2018: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/29406065/urologic-emergencies
#15
REVIEW
Adarsh S Manjunath, Matthias D Hofer
Urologic emergencies can involve the kidneys, ureters, bladder, urethra, penis, scrotum, or testicles. History and physical examination are essential to diagnosis, whereas imaging is increasingly used to confirm diagnoses. Acute urinary retention should be relieved with Foley placement. Penile emergencies include paraphimosis, which can be treated by foreskin reduction, whereas penile fracture and priapism require urologic intervention. Fournier gangrene and testicular torsion are scrotal emergencies requiring emergent surgery...
March 2018: Medical Clinics of North America
https://www.readbyqxmd.com/read/29394981/isolated-involvement-of-penis-in-fournier-s-gangrene-a-rare-possibility
#16
Partha Pratim Deb, Arpan Choudhary, Ranjan Kumar Dey, Ranjit Kumar Das
skin and subcutaneous tissue. Penis may be secondarily affected in some cases; however, primary isolated involvement of penis is rare. A 48-year male smoker presented with pain and blackish discoloration of the distal part of penis for the last 4 days which developed following rupture of a papulo-vesicular lesion over the prepuce of penis. It rapidly progressed to involve half of the skin of the penis. The patient was hospitalized and broad spectrum antibiotics were administered parenterally. Emergency wound debridement and urinary diversion by suprapubic cystostomy was done...
February 2018: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/29374769/fournier-s-gangrene-clinical-presentation-of-13-cases
#17
Bolesław Kuzaka, Marta M Wróblewska, Tomasz Borkowski, Dariusz Kawecki, Piotr Kuzaka, Grażyna Młynarczyk, Piotr Radziszewski
BACKGROUND Fournier's gangrene (FG) is a fulminant form of infective, polymicrobial, necrotizing fasciitis of the perineal, genital, and perianal regions. It commonly affects men, but women and children may also develop this type of tissue necrosis. MATERIAL AND METHODS This study is a retrospective analysis of the management of 13 cases of Fournier's gangrene, diagnosed from among about 45 000 patients (men, women, and children) treated in the Department of General, Oncological, and Functional Urology (Medical University of Warsaw) from 1995 to 2013...
January 28, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29370639/re-low-volume-vs-high-volume-centers-and-management-of-fournier-s-gangrene-in-washington-state
#18
David F Penson
No abstract text is available yet for this article.
August 2017: Journal of Urology
https://www.readbyqxmd.com/read/29316869/fournier-s-gangrene-a-rare-manifestation-of-chikungunya-fever
#19
Apoorv Goel, Shalabh Gupta, Ayush Agarwal, Nitin Shiwach, Vishal Chawda, Tripta S Bhagat
No abstract text is available yet for this article.
January 2018: Tropical Doctor
https://www.readbyqxmd.com/read/29284566/surviving-fournier-s-gangrene-multivariable-analysis-and-a-novel-scoring-system-to-predict-length-of-stay
#20
Saum B Ghodoussipour, Daniel Gould, Jacob Lifton, Ido Badash, Aaron Krug, Gus Miranda, Jeffrey Loh-Doyle, Joseph Carey, Hooman Djaladat, Leo Doumanian, David Ginsberg
BACKGROUND: There is no contemporary scoring system to predict hospital length of stay and morbidity in Fournier's gangrene. A retrospective study was conducted to formulate a scoring system to predict duration of hospitalization, resource utilization, need for reconstruction, morbidity and mortality. METHODS: A retrospective chart review was performed on 54 patients treated for FG from 2010-2016 at LAC+USC Medical Center, the largest public hospital in Los Angeles County...
December 14, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
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