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Surendra Kumar
BACKROUND: The outbreak of H1N1 virus had previously reported in India during 2009 flu pandemic. In 2015, the outbreak became widespread throughout India. The states of Gujarat and Rajasthan are severely elected. We studied an outbreak of H1N1 Virus in north-west zone of Rajasthan 2015. OBJECTIVE: To demonstrate the current epidemiological scenario of swine flu (H1N1) in north-west zone of Rajasthan with different demographic factors. METHODS: We screened total 6390 patients...
July 2016: Journal of the Association of Physicians of India
Melanie L Chang, April Nowell
For the past few years, people everywhere have been "going Paleo." Websites and social media touting the benefits of eating a "Paleo diet" and following a "Paleolithic life style" serve as calls to arms for health-conscious individuals seeking information about the latest health and fitness trends. Many of these people participate in programs such as Crossfit, which involve major social and life-style modification components and therefore facilitate the dissemination of dietary fads.(1) The PALEOf(x)(TM) conference, which bills itself as "the world's premier holistic wellness event," has attracted sellout crowds of thousands of attendees for the last four years...
September 2016: Evolutionary Anthropology
Paul Richard Edwin Jarvis
Emergency departments (ED) face significant challenges in delivering high quality and timely patient care on an ever-present background of increasing patient numbers and limited hospital resources. A mismatch between patient demand and the ED's capacity to deliver care often leads to poor patient flow and departmental crowding. These are associated with reduction in the quality of the care delivered and poor patient outcomes. A literature review was performed to identify evidence-based strategies to reduce the amount of time patients spend in the ED in order to improve patient flow and reduce crowding in the ED...
June 2016: Clin Exp Emerg Med
Eamonn B Mallon, Harindra E Amarasinghe, Swidbert R Ott
Desert locusts (Schistocerca gregaria) show a dramatic form of socially induced phenotypic plasticity known as phase polyphenism. In the absence of conspecifics, locusts occur in a shy and cryptic solitarious phase. Crowding with conspecifics drives a behavioural transformation towards gregariousness that occurs within hours and is followed by changes in physiology, colouration and morphology, resulting in the full gregarious phase syndrome. We analysed methylation-sensitive amplified fragment length polymorphisms (MS-AFLP) to compare the effect of acute and chronic crowding on DNA methylation in the central nervous system...
October 18, 2016: Scientific Reports
Jumpei F Yamagishi, Nen Saito, Kunihiko Kaneko
As cells grow and divide under a given environment, they become crowded and resources are limited, as seen in bacterial biofilms and multicellular aggregates. These cells often show strong interactions through exchanging chemicals, as evident in quorum sensing, to achieve mutualism and division of labor. Here, to achieve stable division of labor, three characteristics are required. First, isogenous cells differentiate into several types. Second, this aggregate of distinct cell types shows better growth than that of isolated cells without interaction and differentiation, by achieving division of labor...
October 2016: PLoS Computational Biology
Carmine Di Rienzo, Paolo Annibale
The determination of the mode and rapidity of motion of individual molecules within a biological sample is becoming a more and more common analysis in biophysical investigations. Single molecule tracking (SMT) techniques allow reconstructing the trajectories of individual molecules within a movie, provided that the position from one frame to the other can be correctly linked. The outcomes, however, appear to depend on the specific method used, and most techniques display a limitation to capture fast modes of motion in a crowded environment...
October 1, 2016: Optics Letters
Christopher A Benner, Erika Mora, Emily Mueller, F Jacob Seagull, Kelly Walkovich, Kaleena Johnson, Schuyler Halverson, Ed Rothman, George Hucks, John G Younger, Michele M Nypaver
OBJECTIVES: Febrile neutropenic pediatric patients are at heightened risk for serious bacterial infections, and rapid antibiotic administration (in <60 minutes) improves survival. Our objectives were to reduce the time-to-antibiotic (TTA) administration and to evaluate the effect of overall emergency department (ED) busyness on TTA. METHODS: This study was a quality improvement initiative with retrospective chart review to reduce TTA in febrile children with underlying diagnosis of cancer or hematologic immunodeficiency who visited the pediatric ED...
October 4, 2016: Pediatric Emergency Care
Frederick A Jakobiec, Anna M Stagner, Natalie Homer, Michael K Yoon
PURPOSE: To further define the histopathologic features of breast carcinoma conducive to orbital metastasis. METHODS: Ten new female patients with orbital or eyelid breast cancer metastases encountered between 2011 and 2016 had their medical records reviewed for determining their clinical characteristics. Microscopic glass slides from biopsies and immunohistochemical test results were also analyzed. Biomarkers studied included cytokeratin 7, nuclear estrogen and progesterone receptors, HER2, and E-cadherin...
October 5, 2016: Ophthalmic Plastic and Reconstructive Surgery
Jun Watanabe, Mitsuyoshi Ota, Yusuke Suwa, Atsushi Ishibe, Hidenobu Masui, Kaoru Nagahori
INTRODUCTION: Single-incision laparoscopic colectomy is technically limited because of such factors as instrument crowding, in-line viewing, and insufficient countertraction. In particular, it is technically difficult to cut the distal rectum from the umbilicus using an articulating linear stapler in single-incision laparoscopic anterior resection. TECHNIQUE: After treating the mesorectum, the 5-mm trocar is replaced with a 12-mm trocar. The cartridge of the curved stapler is mounted while the shaft of the stapler is inserted into the 12-mm port extracorporeally...
November 2016: Diseases of the Colon and Rectum
Marc A Bouffard, Wayne T Cornblath, Joseph F Rizzo, Michael S Lee, Lindsey B DeLott, Eric R Eggenberger, Nurhan Torun
BACKGROUND: Transient monocular vision loss (TMVL) is an alarming symptom owing to potentially serious etiologies such as thromboembolism or giant cell arteritis. Our objective is to describe the phenomenon of TMVL present on awakening, which may represent a distinct and benign entity. METHODS: We performed a retrospective observational case series of 29 patients who experienced TMVL on awakening. Patients who described monocular dimming or blackout of vision were included, and those with blurred vision, concurrent eye pain, and binocular vision loss were excluded...
September 29, 2016: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
Emerson Tavares de Sousa, Beatriz Feitosa da Silva, Fabiana Barros Marinho Maia, Franklin Delano Soares Forte, Fábio Correia Sampaio
BACKGROUND: The normative orthodontic treatment need, established by dental professionals during the dental appointment, becomes ineffective when it does not evaluate all the factors that influence the decision-making process, including individuals' perception and satisfaction with their dental appearance. Therefore, the purpose of this study was to investigate the perception of children and their mothers as regards orthodontic treatment need and satisfaction with dental aesthetics and test if these variables are associated with the objective orthodontic treatment needs, assessed by the Dental Aesthetic Index (DAI)...
December 2016: Progress in Orthodontics
Zhijie Song, Rui Shi, Jie Jia, Jian Wang
Sentiment contagion is similar to an infectious disease that spreads in a crowd. In this study, we extend the proposed SOSa-SPSa model (susceptible-optimistic-susceptible and susceptible-pessimistic-susceptible) by considering the interaction between optimists and pessimists. Simulation results show that our model is reasonable and can better explain the entire contagion process by considering three groups of people. The recovery speed of pessimists has an obvious regulative effect on the number of pessimists and the possibility of optimists coming in contact with pessimists to be infected as pessimism plays a greater role than that of reverting to susceptibility...
2016: Computational and Mathematical Methods in Medicine
Xian-Hua Wang, Qian Dong, Ling-Ling Ying, Shuai-Shuai Chi, Yao-Han Lan, Yan-Ping Huang, Zhao-Sheng Liu
In this study, a new molecularly imprinted polymer chiral stationary phase (MIP-CSP) was prepared utilizing molecular crowding agent for improvement the selective separation ability. S-amlodipine (S-AML), methacrylic acid (MAA), ethylene glycol dimethacrylate (EDMA), and polymethyl methacrylate (PMMA) were selected as template, functional monomer, cross-linker, and molecular crowding agent, respectively. The composition of formulas for MIP-CSP was optimized, and the permeability and structural feature of resultant MIP-CSP were characterized...
October 15, 2016: Analytical and Bioanalytical Chemistry
Evelyn K Ansah, Christopher Jm Whitty, Constance Bart-Plange, Margaret Gyapong
BACKGROUND: Most people with febrile illness are treated in the private drug retail sector. Ghana was among nine countries piloting the Global Fund Affordable Medicines Facility - malaria (AMFm). AMFm aimed to: increase artemisinin combination therapy (ACT) affordability; increase ACT availability; increase ACT use; and 'crowd out' artemisinin monotherapies. METHODS: Three censuses were carried out 2 months before (2010), 2 months after and 2.5 years after (2013) the first co-paid ACTs to assess changes in antimalarial (AM) availability and price in private retail shops in a Ghanaian rural district to assess the sustainability of the initial gains...
October 15, 2016: International Health
Luis F Aristizábal, Gabriel Moura Mascarin, Ron Cherry, Bernardo Chaves-Cordoba, Steven P Arthurs
The development of simple and reliable pest sampling programs is needed for growers to adopt economic or aesthetic injury levels. We developed a sampling plan for monitoring chilli thrips Scirtothrips dorsalis Hood populations on KnockOut shrub roses under simulated nursery conditions. The distribution of S. dorsalis among different plant structures revealed that most adults and larvae are found on foliar terminals, when compared with buds and flowers. Based on thrips distribution, the third leaf of actively growing terminals was used to determine a sequential sampling model...
October 15, 2016: Journal of Economic Entomology
Yan Li, Jie Zhang, Dafeng Chen, Pengcheng Yang, Feng Jiang, Xianhui Wang, Le Kang
Locusts are important agricultural pests worldwide and regarded as study models for entomology. However, the absence of targeted gene manipulation systems for locusts has restricted their applications for research. Herein, we report the successful use of the CRISPR/Cas9 system to induce a targeted heritable mutagenesis of the migratory locust, Locusta migratoria. The target sequence of gRNA was designed to disrupt the gene encoding the odorant receptor co-receptor (Orco) and examine the roles of the odorant receptor pathway in the locust...
October 12, 2016: Insect Biochemistry and Molecular Biology
Oleksandr N Kryvenko, Sean R Williamson, Kiril Trpkov, Nilesh S Gupta, Daniel Athanazio, Martin K Selig, Paul Taylor Smith, Cristina Magi-Galluzzi, Merce Jorda
Small cell-like change (SCLC) is a rare prostate lesion which has been described in only two previous studies (total of eight cases). Its relation to possible neuroendocrine differentiation remained unclear. We evaluated 11 SCLC cases with immunohistochemistry and electron microscopy. SCLC was characterized by crowded hyperchromatic small nuclei with scant cytoplasm, rosette-like structures, finely granular chromatin with indistinct nucleoli, and lack of mitoses, apoptoses, and necroses. In nine cases, SCLC was admixed with high-grade cancer, and in two cases, it represented a separate intraductal process, spatially remote from a low-volume Gleason score 6 (grade group 1) cancer...
October 14, 2016: Virchows Archiv: An International Journal of Pathology
J Hizanidis, N Lazarides, G P Tsironis
We report on the emergence of robust multiclustered chimera states in a dissipative-driven system of symmetrically and locally coupled identical superconducting quantum interference device (SQUID) oscillators. The "snakelike" resonance curve of the single SQUID is the key to the formation of the chimera states and is responsible for the extreme multistability exhibited by the coupled system that leads to attractor crowding at the geometrical resonance (inductive-capacitive) frequency. Until now, chimera states were mostly believed to exist for nonlocal coupling...
September 2016: Physical Review. E
Namita Chandra, Sanjay Kumar, Vaibhav Raj, Pawan Kumar Vishwakarma, Sheela Sinha, Ram Prakash Saha
BACKGROUND Jarcho-Levin syndrome, also known as spondylothoracic dysplasia and spondylocostal dysplasia, is characterized by varieties of vertebrae and rib anomalies. Jarcho-Levin syndrome is a clinical-radiological diagnosis with clinical evidence of short neck, short trunk, normal-sized limbs, or increased arm span, and vertebral and rib defects on the skeletal survey. CASE REPORT About 400 cases have been reported in world literature and 18 in our Indian literature. We report the case of a one-day-old female baby with a short trunk, short neck, low hairline, apparently long limbs, protuberant abdomen, mild midfacial dysmorphism, low-set ears, and a high-arched palate...
October 14, 2016: American Journal of Case Reports
Michael J Kral
Inuit in Canada have among the highest suicide rates in the world, and it is primarily among their youth. Risk factors include known ones such as depression, substance use, a history of abuse, and knowing others who have made attempts or have killed themselves, however of importance are the negative effects of colonialism. This took place for Inuit primarily during the government era starting in the 1950s, when Inuit were moved from their family-based land camps to crowded settlements run by white men, and children were removed from their parents and placed into residential or day schools...
November 2016: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
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