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https://www.readbyqxmd.com/read/28231685/unmet-psychosocial-needs-in-adolescents-with-inflammatory-bowel-disease
#1
(no author information available yet)
BACKGROUND: Inflammatory bowel diseases (IBD) are severe medical conditions with adverse impact on the quality of life of both children and their caregivers. IBD are associated with many limitations in personal and interpersonal functioning, and it also restricts the patients' ability to use the full potential (extent) of their capabilities. With the progress and humanization in society, the issue of patients' needs became an important topic; however, the psychosocial functioning and quality of life of adolescents suffering from IBD and their caregivers have been understudied...
October 24, 2016: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28231682/unmet-needs-of-the-patients-with-obsessive-compulsive-disorder
#2
(no author information available yet)
BACKGROUND: Obsessive compulsive disorder (OCD) is a disabling mental disorder with the chronic and difficult course. The disorder is accompanied by numerous limitations in personal and interpersonal functioning. OCD decreases the quality of life and the chance to maintain relationships and professional status. The patients with OCD often experience a severe disabling course of the disorder. Even the individuals, who follow treatment advice, are often still highly symptomatic. In the last decade, the concept of the needs has been assessed as an extent of the traditional outcome evaluation in order to focus on the identification of the specific needs of the patients and their relatives, improve the patients´ overall mental condition and quality of life, and also to increase the treatment effectiveness of the mental disorders...
October 24, 2016: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28231680/-a-review-on-the-advancement-of-internet-based-public-health-surveillance-program
#3
Y Q Zhao, W J Ma
Internet data is introduced into public health arena under the features of fast updating and tremendous volume. Mining and analyzing internet data, researchers can model the internet-based surveillance system to assess the distribution of health-related events. There are two main types of internet-based surveillance systems, i.e. active and passive, which are distinguished by the sources of information. Through passive surveillance system, information is collected from search engine and social media while the active system gathers information through provision of the volunteers...
February 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28231640/mind-the-gap-mechanisms-regulating-the-endothelial-barrier
#4
REVIEW
Mariya Y Radeva, Jens Waschke
The endothelial barrier consists of intercellular contacts localized in the cleft between endothelial cells, which is covered by the glycocalyx in a sieve-like manner. Both types of barrier-forming junctions, i.e. the adherens junction (AJ) serving mechanical anchorage and mechanotransduction and the tight junction (TJ) sealing the intercellular space to limit paracelullar permeability, are tethered to the actin cytoskeleton. Under resting conditions, the endothelium thereby builds a selective layer controlling the exchange of fluid and solutes with the surrounding tissue...
February 23, 2017: Acta Physiologica
https://www.readbyqxmd.com/read/28231639/cell-cycle-rna-regulons-coordinating-early-lymphocyte-development
#5
REVIEW
Alison Galloway, Martin Turner
Lymphocytes undergo dynamic changes in gene expression as they develop from progenitor cells lacking antigen receptors, to mature cells that are prepared to mount immune responses. While transcription factors have established roles in lymphocyte development, they act in concert with post-transcriptional and post-translational regulators to determine the proteome. Furthermore, the post-transcriptional regulation of RNA regulons consisting of mRNAs whose protein products act cooperatively allows RNA binding proteins to exert their effects at multiple points in a pathway...
February 23, 2017: Wiley Interdisciplinary Reviews. RNA
https://www.readbyqxmd.com/read/28231638/comparison-of-the-shock-absorption-capacities-of-different-mouthguards
#6
Melina Simonetta Bochnig, Min-Jung Oh, Theresa Nagel, Fred Ziegler, Paul-Georg Jost-Brinkmann
BACKGROUND/AIMS: In this in vitro study the protective qualities of different mouthguard types were examined during small hard object collisions. The aim was to investigate inconclusive aspects of hard inserts, nylon nets and air spaces as reinforcements in the anterior region and the protection qualities of ethylene vinyl acetate (EVA). MATERIALS AND METHODS: Five different mouthguards with a labial thickness between 2 mm and 11 mm made of materials of varying stiffness were investigated...
February 23, 2017: Dental Traumatology: Official Publication of International Association for Dental Traumatology
https://www.readbyqxmd.com/read/28231636/personalized-thromboprophylaxis-using-a-risk-score-for-the-management-of-pregnancies-with-high-risk-of-thrombosis-a-prospective-clinical-study
#7
Y Dargaud, L Rugeri, C Fleury, C Battie, P Gaucherand, C Huissoud, R C Rudigoz, H Desmurs-Clavel, J Ninet, M C Trzeciak
BACKGROUND: Patients with thrombophilia and/or a history of venous thromboembolism (VTE) are at risk of thrombosis during pregnancy. A risk score for pregnancies with increased risk of VTE was previously described by our group (Lyon-VTE-score). OBJECTIVES: The aim of this prospective study was to assess the efficacy and safety of our score-based prophylaxis strategy in 542 pregnancies managed between 2005 and 2015 in Lyon University Hospitals. PATIENTS/METHODS: Of 445 patients included in the study, 36 had several pregnancies during the study period...
February 23, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/28231634/from-endogenous-to-exogenous-pattern-formation-invasive-plant-species-changes-the-spatial-distribution-of-a-native-ant
#8
Kevin Li, Yifan He, Susanna K Campbell, A Shawn Colborn, Eliot L Jackson, Austin Martin, Ivan V Monagan, Theresa Wei Ying Ong, Ivette Perfecto
Invasive species are a significant threat to global biodiversity, but our understanding of how invasive species impact native communities across space and time remains limited. Based on observations in an old field in Southeast Michigan spanning 35 years, our study documents significant impacts of habitat change, likely driven by the invasion of the shrub, Elaeagnus umbellata, on the nest distribution patterns and population demographics of a native ant species, Formica obscuripes. Landcover change in aerial photos indicates that E...
February 23, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28231633/barriers-to-regaining-control-within-a-constructivist-grounded-theory-of-family-resilience-in-icu-living-with-uncertainty
#9
Pauline Wong, Pranee Liamputtong, Susan Koch, Helen Rawson
This paper discusses families' experiences of their interactions when a relative is admitted unexpectedly to an Australian intensive care unit BACKGROUND: The overwhelming emotions associated with the unexpected admission of a relative to an intensive care unit (ICU) are often due to the uncertainty surrounding the condition of their critically ill relative. There is limited in-depth understanding of the nature of uncertainty experienced by families in ICU, and interventions perceived by families to minimise their uncertainty are not well documented...
February 23, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28231632/reliability-and-validity-of-the-chinese-version-of-the-self-care-ability-scale-for-the-elderly
#10
Han Gao, Ulrika Söderhamn, Christina Cliffordson, Lina Guo, Qiyun Guo, Kun Liu
AIMS AND OBJECTIVES: To translate the Self-care Ability Scale for the Elderly into Simplified Chinese, and to test the Chinese version of the scale regarding its reliability and validity among older people. BACKGROUND: Self-care is an important topic in nursing. When assessing older people's self-care ability, it is essential that a reliable and valid instrument is used. DESIGN: This study employed across-sectional design. METHODS: We translated the English version of the Self-care Ability Scale for the Elderly into Simplified Chinese according to Brislin's translation guidelines, and carried out a questionnaire survey among 610 older people, including both community-dwelling people and hospital patients, in Jinzhou City, People's Republic of China...
February 23, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28231631/commentary-response-frailty-not-just-about-old-people-reply-to-smith-gd-kydd-a-2017-getting-care-of-older-people-right-the-need-for-appropriate-frailty-assessment
#11
Sunita R Jha, Julee Mcdonagh, Caleb Ferguson, Peter S Macdonald, Phillip J Newton
As highlighted in a recent editorial, the ageing population and burden of frailty amongst those aged 60 years and older represents an impending challenge for individuals and health care systems globally (Smith & Kydd 2017). As frailty is largely considered a geriatric syndrome, research has primarily occurred within elderly community dwelling populations (Fried et al. 2001). However, it is important to highlight that not all older people are frail; and conversely not all younger people are non-frail. With frailty research expanding its scope beyond geriatrics over the last 2 decades, our understanding of this syndrome and its complexities has progressed...
February 23, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28231630/the-role-of-the-family-in-supporting-the-self-management-of-chronic-conditions-a-qualitative-systematic-review
#12
Whitehead Lisa, Towell Amanda, Abu-Qamar Ma'en, Cole-Heath Amanda
AIMS AND OBJECTIVES: To explore the contribution of family members in promoting and supporting the self-management of chronic conditions among adult family members. BACKGROUND: The prevalence of chronic disease continues to grow globally. The role of the family in chronic condition management and support for self-management has received little attention. DESIGN: A systematic review of qualitative literature using the Joanna Briggs Institute approach for qualitative systematic reviews...
February 23, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28231629/the-evaluation-of-physical-activity-for-community-dwelling-patients-with-hypertension
#13
Chunhua Ma
AIMS AND OBJECTIVES: The study aimed to evaluate the proportion of Chinese patients with hypertension who meet the Chinese Hypertension Management Guideline recommendations for weekly physical activity and to determine possible associated factors that impact meeting the weekly physical activity recommendation. BACKGROUND: Accurate evaluation of physical activity levels for hypertensive patients is important to determine patients' health outcomes and intervention measures...
February 23, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28231628/the-lived-experience-of-recovery-during-the-first-six-months-after-colorectal-cancer-surgery
#14
Jenny Jakobsson, Ewa Idvall, Christine Kumlien
AIMS AND OBJECTIVES: The objective of this study was to describe the lived experience of recovery during the first six months after colorectal cancer surgery. BACKGROUND: Colorectal cancer is the third most common cancer-diagnose worldwide. Early discharge places demands on health care professionals to prepare patients for their return home and to provide them with appropriate support throughout the recovery process. This requires knowledge of what it is like to recover from colorectal cancer surgery...
February 23, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28231627/factors-predicting-recovery-from-suicide-in-attempted-suicide-patients
#15
Fan-Ko Sun, Chu-Yun Lu, Yun Shan Tseng, Chun-Ying Chiang
AIMS AND OBJECTIVES: The aim of this study was to explore the factors predicting suicide recovery and to provide guidance for healthcare professionals when caring for individuals who have attempted suicide. BACKGROUND: The high rate of suicide is a global health problem. Suicide prevention has become an important issue in contemporary mental health. Most suicide research has focused on suicidal prevention and care. There is a lack of research on the factors predicting suicidal recovery DESIGN: A cross-sectional design was adopted...
February 23, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28231625/experimental-study-on-1-25-oh-2-d3-amelioration-of-oral-lichen-planus-through-regulating-nf-%C3%AE%C2%BAb-signaling-pathway
#16
Jie Du, Ran Li, Feiyan Yu, Fang Yang, Jinhua Wang, Qingyong Chen, Xiangyu Wang, Bin Zhao, Fang Zhang
OBJECTIVE: To explore the protective function of vitamin D (VD)/vitamin D receptor (VDR) on the development of oral lichen planus (OLP) and elaborate the underling mechanism of it. METHODS: H&E staining, myeloid Peroxidase (MPO) assays, quantitative PCR (qPCR), western blotting and Elisa were used to test the human biopsies and serum. QPCR, western blotting, Elisa and siRNA transfection were also performed in LPS-induced keratinocytes to observe the functions of vitamin D and VDR...
February 23, 2017: Oral Diseases
https://www.readbyqxmd.com/read/28231624/targets-and-mechanisms-in-prevention-of-parkinson-s-disease-through-immunomodulatory-treatments
#17
REVIEW
Marianne von Euler Chelpin, Thomas Vorup-Jensen
Parkinson's Disease (PD) is the second most common neurodegenerative disease in the world, however, there is no cure for it. Current treatments only relieve some of the symptoms, without ceasing the disease, and lose efficacy with prolonged treatment. Considerable evidence shows that persistent inflammatory responses, involving T cell infiltration and glial cell activation, are common characteristics of human patients and play a crucial role in the degeneration of dopaminergic neurons. Therefore, it is important to develop therapeutic strategies that can impede or halt the disease through the modulation of the peripheral immune system by aiming at controlling the existing neuroinflammation...
February 23, 2017: Scandinavian Journal of Immunology
https://www.readbyqxmd.com/read/28231623/compassion-fatigue-in-nurses-a-metasynthesis
#18
Anna G W Nolte, Charlene Downing, Annie Temane, Marie Hastings-Tolsma
AIM: The purpose of this research was to interpret the body of qualitative work focusing on compassion fatigue to distill a common understanding that could then be applied to nursing care. BACKGROUND: Complex demands place extraordinary stress on nurses struggling to work in overburdened healthcare systems. The result can be the inability to care well for others, leading to compassion fatigue, burnout, and increased numbers leaving the profession. Meta-synthesis offers a means of more fully illuminating compassion fatigue and further understanding of practices which might reduce its negative consequences...
February 23, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28231622/gingival-crevicular-fluid-levels-of-monocyte-chemoattractant-protein-mcp-1-in-patients-with-aggressive-periodontitis
#19
Sadiye Gunpinar, Nilgun Ozlem Alptekin, Niyazi Dundar
OBJECTIVES: The purpose of this study was to investigate the gingival crevicular fluid (GCF) levels of Monocyte Chemoattractant Protein (MCP)-1 in aggressive periodontitis (AgP) and whether GCF MCP-1 levels differ among localized (L) AgP and generalized (G) AgP. MATERIAL AND METHODS: A total of 160 subjects including, 80 AgP and 80 age and gender matched periodontally healthy (H) controls were recruited in this cross-sectional study (NCT02927704). GCF samples were collected from 160 patients including 50 LAgP, 30 GAgP and 80 H...
February 23, 2017: Oral Diseases
https://www.readbyqxmd.com/read/28231620/sustaining-guideline-implementation-a-multi-site-perspective-on-activities-challenges-and-supports
#20
Kathryn Smith Higuchi, Barbara Davies, Jenny Ploeg
AIMS AND OBJECTIVES: To examine activities conducted, challenges encountered, and supports used when sustaining nursing practice guideline implementation in multiple health care organizations over three years. BACKGROUND: Numerous models and frameworks exist to guide the implementation of guidelines, yet very few focus on sustaining improved practice changes. It is not known if one intervention or multiple interventions are required, nor the long-term activities, challenges, and supports for sustaining improved practices...
February 23, 2017: Journal of Clinical Nursing
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