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https://www.readbyqxmd.com/read/28102352/reference-free-high-resolution-measurement-method-of-timing-jitter-spectra-of-optical-frequency-combs
#1
Dohyeon Kwon, Chan-Gi Jeon, Junho Shin, Myoung-Sun Heo, Sang Eon Park, Youjian Song, Jungwon Kim
Timing jitter is one of the most important properties of femtosecond mode-locked lasers and optical frequency combs. Accurate measurement of timing jitter power spectral density (PSD) is a critical prerequisite for optimizing overall noise performance and further advancing comb applications both in the time and frequency domains. Commonly used jitter measurement methods require a reference mode-locked laser with timing jitter similar to or lower than that of the laser-under-test, which is a demanding requirement for many laser laboratories, and/or have limited measurement resolution...
January 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28095900/post-stroke-dementia-a-comprehensive-review
#2
REVIEW
Milija D Mijajlović, Aleksandra Pavlović, Michael Brainin, Wolf-Dieter Heiss, Terence J Quinn, Hege B Ihle-Hansen, Dirk M Hermann, Einor Ben Assayag, Edo Richard, Alexander Thiel, Efrat Kliper, Yong-Il Shin, Yun-Hee Kim, SeongHye Choi, San Jung, Yeong-Bae Lee, Osman Sinanović, Deborah A Levine, Ilana Schlesinger, Gillian Mead, Vuk Milošević, Didier Leys, Guri Hagberg, Marie Helene Ursin, Yvonne Teuschl, Semyon Prokopenko, Elena Mozheyko, Anna Bezdenezhnykh, Karl Matz, Vuk Aleksić, DafinFior Muresanu, Amos D Korczyn, Natan M Bornstein
Post-stroke dementia (PSD) or post-stroke cognitive impairment (PSCI) may affect up to one third of stroke survivors. Various definitions of PSCI and PSD have been described. We propose PSD as a label for any dementia following stroke in temporal relation. Various tools are available to screen and assess cognition, with few PSD-specific instruments. Choice will depend on purpose of assessment, with differing instruments needed for brief screening (e.g., Montreal Cognitive Assessment) or diagnostic formulation (e...
January 18, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28095118/modeling-and-optimization-of-lime-based-stabilization-in-high-alkaline-arsenic-bearing-sludges-with-a-central-composite-design
#3
Jie Lei, Bing Peng, Xiaobo Min, Yanjie Liang, Yang You, Liyuan Chai
This study focuses on the modeling and optimization of lime-based stabilization in high alkaline arsenic-bearing sludges (HAABS) and describes the relationship between the arsenic leachate concentration (ALC) and stabilization parameters to develop a prediction model for obtaining the optimal process parameters and conditions. A central composite design (CCD) along with response surface methodology (RSM) was conducted to model and investigate the stabilization process with three independent variables: the Ca/As mole ratio, reaction time and liquid/solid ratio, along with their interactions...
January 17, 2017: Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering
https://www.readbyqxmd.com/read/28093558/glutamatergic-synapses-are-structurally-and-biochemically-complex-because-of-multiple-plasticity-processes-long-term-potentiation-long-term-depression-short-term-potentiation-and-scaling
#4
REVIEW
John Lisman
Synapses are complex because they perform multiple functions, including at least six mechanistically different forms of plasticity. Here, I comment on recent developments regarding these processes. (i) Short-term potentiation (STP), a Hebbian process that requires small amounts of synaptic input, appears to make strong contributions to some forms of working memory. (ii) The rules for long-term potentiation (LTP) induction in CA3 have been clarified: induction does not depend obligatorily on backpropagating sodium spikes but, rather, on dendritic branch-specific N-methyl-d-aspartate (NMDA) spikes...
March 5, 2017: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/28092847/repetitive-transcranial-magnetic-stimulation-for-the-treatment-of-post-stroke-depression-a-systematic-review-and-meta-analysis-of-randomized-controlled-clinical-trials
#5
REVIEW
XinYi Shen, MingYi Liu, Yu Cheng, Cui Jia, XinYue Pan, QingYun Gou, XinLian Liu, Hui Cao, LuShun Zhang
BACKGROUND: Every year, more than fifteen million people worldwide experience a stroke, nearly 30% of stroke survivors are likely to experience post-stroke depression (PSD). Repetitive transcranial magnetic stimulation (rTMS) is one of the emerging techniques which assist in targeting rehabilitation after stroke. Although deterioration of PSD greatly affects the recovery and quality of life of stroke sufferers, the effect of rTMS therapy has not been systematically studied. OBJECTIVE: A systematic review and meta-analysis was conducted to determine the effect of rTMS on PSD...
January 10, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28089531/predicting-the-particle-size-distribution-of-eroded-sediment-using-artificial-neural-networks
#6
María Paz Lagos-Avid, Carlos A Bonilla
Water erosion causes soil degradation and nonpoint pollution. Pollutants are primarily transported on the surfaces of fine soil and sediment particles. Several soil loss models and empirical equations have been developed for the size distribution estimation of the sediment leaving the field, including the physically-based models and empirical equations. Usually, physically-based models require a large amount of data, sometimes exceeding the amount of available data in the modeled area. Conversely, empirical equations do not always predict the sediment composition associated with individual events and may require data that are not always available...
January 12, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28089249/redundant-and-fault-tolerant-algorithms-for-real-time-measurement-and-control-systems-for-weapon-equipment
#7
Dan Li, Xiaoguang Hu
Because of the high availability requirements from weapon equipment, an in-depth study has been conducted on the real-time fault-tolerance of the widely applied Compact PCI (CPCI) bus measurement and control system. A redundancy design method that uses heartbeat detection to connect the primary and alternate devices has been developed. To address the low successful execution rate and relatively large waste of time slices in the primary version of the task software, an improved algorithm for real-time fault-tolerant scheduling is proposed based on the Basic Checking available time Elimination idle time (BCE) algorithm, applying a single-neuron self-adaptive proportion sum differential (PSD) controller...
January 12, 2017: ISA Transactions
https://www.readbyqxmd.com/read/28088287/insulin-like-growth-factor-binding-protein-3-deficiency-leads-to-behavior-impairment-with-monoaminergic-and-synaptic-dysfunction
#8
Hongmei Dai, Yu-Ichi Goto, Masayuki Itoh
Insulin-like growth factor binding protein (IGFBP)-3 regulates IGF bioactivity, induces apoptosis, and inhibits cell growth independent of IGFs, but the functional role of IGFBP3 in the brain is not clear. In the present study, we revealed the effect of IGFBP3 on the brain by characterizing the phenotype of Igfbp3-null mice. Compared with wild-type mice, Igfbp3-null mice had significantly decreased IGF-1 content in the brain but no change in weights of brain and body. In Igfbp3-null mice, the number of dendritic spines was significantly reduced, and the dendritic diameter was thickening...
January 10, 2017: American Journal of Pathology
https://www.readbyqxmd.com/read/28077487/calcium-permeable-ampa-receptors-and-silent%C3%A2-synapses-in-cocaine-conditioned-place-preference
#9
Avani Shukla, Anna Beroun, Myrto Panopoulou, Peter A Neumann, Seth Gn Grant, M Foster Olive, Yan Dong, Oliver M Schlüter
Exposure to cocaine generates silent synapses in the nucleus accumbens (NAc), whose eventual unsilencing/maturation by recruitment of calcium-permeable AMPA-type glutamate receptors (CP-AMPARs) after drug withdrawal results in profound remodeling of NAc neuro-circuits. Silent synapse-based NAc remodeling was shown to be critical for several drug-induced behaviors, but its role in acquisition and retention of the association between drug rewarding effects and drug-associated contexts has remained unclear. Here, we find that the postsynaptic proteins PSD-93, PSD-95, and SAP102 differentially regulate excitatory synapse properties in the NAc...
January 11, 2017: EMBO Journal
https://www.readbyqxmd.com/read/28073076/spastic-diplegia-in-preterm-born-children-executive-function-impairment-and-neuroanatomical-correlates
#10
Maria Chiara Di Lieto, Paola Brovedani, Chiara Pecini, Anna Maria Chilosi, Vittorio Belmonti, Franco Fabbro, Cosimo Urgesi, Simona Fiori, Andrea Guzzetta, Silvia Perazza, Elisa Sicola, Giovanni Cioni
BACKGROUND: The neuropsychological literature on preterm-born children with spastic diplegia due to periventricular leukomalacia is convergent in reporting deficits in non-verbal intelligence and in visuo-spatial abilities. Nevertheless, other cognitive functions have found to be impaired, but data are scant and not correlated with neuroimaging findings. AIMS: This study analyzes the neuropsychological strengths and weaknesses in preterm-born children with spastic diplegia (pSD) and their relationships with neuroanatomical findings, investigated by a novel scale for MRI classification...
January 7, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28060906/steady-state-motion-visual-evoked-potential-ssmvep-based-on-equal-luminance-colored-enhancement
#11
Wenqiang Yan, Guanghua Xu, Min Li, Jun Xie, Chengcheng Han, Sicong Zhang, Ailing Luo, Chaoyang Chen
Steady-state visual evoked potential (SSVEP) is one of the typical stimulation paradigms of brain-computer interface (BCI). It has become a research approach to improve the performance of human-computer interaction, because of its advantages including multiple objectives, less recording electrodes for electroencephalogram (EEG) signals, and strong anti-interference capacity. Traditional SSVEP using light flicker stimulation may cause visual fatigue with a consequent reduction of recognition accuracy. To avoid the negative impacts on the brain response caused by prolonged strong visual stimulation for SSVEP, steady-state motion visual evoked potential (SSMVEP) stimulation method was used in this study by an equal-luminance colored ring-shaped checkerboard paradigm...
2017: PloS One
https://www.readbyqxmd.com/read/28053818/association-between-serum-magnesium-levels-and-depression-in-stroke-patients
#12
Yingying Gu, Kai Zhao, Xiaoqian Luan, Zhihua Liu, Yan Cai, Qiongzhang Wang, Beilei Zhu, Jincai He
Post-stroke depression (PSD) is a common psychiatric complication of stroke that is associated with a poor outcome in stroke patients. Our aim was to assess the association between the serum magnesium levels and the presence of PSD in Chinese patients. Two hundred nine stroke patients were included in the study. Depressive symptoms were measured by the 17-Hamilton Rating Scale for Depression at 3 months after stroke. Based on the depressive symptoms, diagnoses of depression were made in line with the DSM-IV criteria for PSD...
December 2016: Aging and Disease
https://www.readbyqxmd.com/read/28050794/heterogeneity-in-synaptogenic-profile-of-astrocytes-from-different-brain-regions
#13
Andrea Schmidt Buosi, Isadora Matias, Ana Paula Bergamo Araujo, Carolina Batista, Flávia Carvalho Alcantara Gomes
Astrocytes, the most abundant glial cells in the central nervous system (CNS), comprise a heterogeneous population of cells. However, how this heterogeneity impacts their function within brain homeostasis and response to injury and disease is still largely unknown. Recently, astrocytes have been recognized as important regulators of synapse formation and maturation. Here, we analyzed the synaptogenic property of astrocytes from different regions of the CNS. The effect of conditioned medium derived from astrocytes (astrocyte-conditioned medium (ACM)) from cerebral cortex, hippocampus, midbrain and cerebellum, in synapse formation, was evaluated...
January 3, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28048441/su-f-t-506-development-and-commissioning-of-the-effective-and-efficient-grid-therapy-using-high-dose-rate-flattening-filter-free-beam-and-multileaf-collimator
#14
M Liu, N Wen, C Beyer, F Siddiqui, I Chetty, B Zhao
PURPOSE: Treating bulky tumors with grid therapy (GT) has demonstrated high response rates. Long delivery time (∼15min), with consequent increased risk of intrafraction motion, is a major disadvantage of conventional MLC-based GT (MLC-GT). The goal of this study was to develop and commission a MLC-GT technique with similar dosimetric characteristics, but more efficient delivery. METHODS: Grid plan was designed with 10X-FFF (2400MU/min) beam and MLC in a commercial treatment planning system (TPS)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048435/th-cd-201-04-a-study-of-cherenkov-light-generated-and-collected-in-plastic-scintillation-detector
#15
L Archambault, P Papaconstadopoulos, J Seuntjens, H Bouchard
PURPOSE: To study Cherenkov light emission in plastic scintillation detectors (PSDs) from a theoretical point of view to identify situations that may arise where the calibration coefficient obtained in one condition is not applicable to another condition. By identifying problematic situations, we hope to provide guidance on how to confidently use PSDs. METHODS: Cherenkov light emission in PSD was modelled using basic physical principles. In particular, changes in refractive index as a function of wavelength were accounted for using the Sellmeier empirical equation...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048423/we-fg-bra-08-potential-role-of-the-glycolytic-oscillator-in-acute-hypoxia-in-tumors
#16
L Che Fru, E Adamson, D Campos, S Fain, S Jacques, A van der Kogel, K Nickel, C Song, R Kimple, M Kissick
PURPOSE: Oscillatory dynamics in acute hypoxia have been observed, but poorly understood. They have mostly been attributed to vascular perturbations, but no link has yet been made to metabolic causes. We set out to determine the fundamental frequencies and test for coherence in tumor oxygen dynamics and spatial properties. METHODS: Severe combined immunodeficient (SCID) mice were inoculated onto bilateral flanks with human derived head and neck carcinoma (UW-SCC22) cell line xenografts...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048411/th-cd-bra-12-impact-of-a-magnetic-field-on-the-response-from-a-plastic-scintillation-detector
#17
F Therriault-Proulx, Z Wen, G Ibbott, S Beddar
PURPOSE: To study the effect of a strong magnetic field on the scintillation and the stem effect from a plastic scintillation detector (PSD) and evaluate its accuracy to measure dose. METHODS: A plastic scintillation detector and a bare plastic fiber were placed inside a magnet of adjustable field strength (B=0-1.5T) and irradiated by a 6-MV photon beam (Elekta Versa HD LINAC). The PSD was built in-house using a scintillating fiber (BCF-60, 3-mm long × 1-mm diameter) coupled to an optical fiber similar to the bare fiber (PMMA, 12-m long, 1-mm diameter)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048181/su-f-p-44-a-direct-estimate-of-peak-skin-dose-for-interventional-fluoroscopy-procedures
#18
V Weir, J Zhang
PURPOSE: There is an increasing demand for medical physicist to calculate peak skin dose (PSD) for interventional fluoroscopy procedures. The dose information (Dose-Area-Product and Air Kerma) displayed in the console cannot directly be used for this purpose. Our clinical experience shows that the use of the existing methods may overestimate or underestimate PSD. This study attempts to develop a direct estimate of PSD from the displayed dose metrics. METHODS: An anthropomorphic torso phantom was used for dose measurements for a common fluoroscopic procedure...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047968/tu-d-209-04-how-useful-are-indirect-dose-metrics-for-estimating-peak-skin-dose-in-interventional-cardiology
#19
A Jones, A Pasciak
PURPOSE: The purpose of this study was to determine if a relationship between indirect dose metrics and PSD could be established for fluoroscopically-guided interventional cardiology procedures. METHODS: PSD were measured directly using XR-RV3 radiochromic film for 94 consecutive fluoroscopically guided interventional cardiology procedures performed at two sites. Procedures were both diagnostic and therapeutic in nature. Radiation dose structured reports (RDSR) were collected for each procedure and used to calculate indirect estimates of PSD which were compared to the measured PSD...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047907/th-ab-207a-03-skin-dose-to-patients-receiving-multiple-cta-and-ct-exams-of-the-head
#20
R D Nawfel, G Young
PURPOSE: To measure patient skin dose from CT angiography (CTA) and CT exams of the head, and determine if patients having multiple exams could receive cumulative doses that approach or exceed deterministic thresholds. METHODS: This study was HIPAA compliant and conducted with IRB approval. Patient skin doses were measured over a 4 month period using nanoDot OSL dosimeters placed on the head of 52 patients for two CT scanners. On each scanner, 26 patients received CT exams (scanner 1: 10 females, 16 males, mean age 64...
June 2016: Medical Physics
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