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https://www.readbyqxmd.com/read/29791448/abundance-and-distribution-of-microplastics-within-surface-sediments-of-a-key-shellfish-growing-region-of-canada
#1
T N Kazmiruk, V D Kazmiruk, L I Bendell
The abundance and distribution of microplastics within 5 sediment size classes (>5000 μm, 1000-5000 μm, 250-1000 μm, 250-0.63 μm and < 0.63 μm) were determined for 16 sites within Lambert Channel and Baynes Sound, British Columbia, Canada. This region is Canada's premier growing area for the Pacific oyster (Crassostrea gigas). Microplastics were found at all sampling locations indicating widespread contamination of this region with these particles. Three types of microplastics were recovered: microbeads, which occurred in the greatest number (up to 25000/kg dry sediment) and microfibers and microfragments, which were much less in number compared with microbeads and occurred in similar amounts (100-300/kg dry sediment)...
2018: PloS One
https://www.readbyqxmd.com/read/29789934/induction-prednisone-dosing-for-childhood-nephrotic-syndrome-how-low-should-we-go
#2
Matthew Sibley, Abishek Roshan, Alanoud Alshami, Marisa Catapang, Jasper J Jöbsis, Trevor Kwok, Nonnie Polderman, Jennifer Sibley, Douglas G Matsell, Cherry Mammen
BACKGROUND: Historically, children with nephrotic syndrome (NS) across British Columbia (BC), Canada have been cared for without formal standardization of induction prednisone dosing. We hypothesized that local historical practice variation in induction dosing was wide and that children treated with lower doses had worse relapsing outcomes. METHODS: This retrospective cohort study included 92 NS patients from BC Children's Hospital (1990-2010). We excluded secondary causes of NS, age < 1 year at diagnosis, steroid resistance, and incomplete induction due to early relapse...
May 22, 2018: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/29788975/activism-and-scientific-research-20-years-of-community-action-by-the-vancouver-area-network-of-drug-users
#3
Ehsan Jozaghi, Alissa M Greer, Hugh Lampkin, Jane A Buxton
BACKGROUND: Over the past several decades, there have been numerous peer-reviewed articles written about people who use drugs (PWUDs) from the Downtown Eastside neighborhood of Vancouver, Canada. While individual researchers have engaged and acknowledged this population as participants and community partners in their work, there has been comparatively little attention given to the role of PWUDs and drug user organizations in directing, influencing, and shaping research agendas. METHODS: In this community-driven research, we examine 20 years of peer-reviewed studies, university theses, books, and reports that have been directed, influenced, and shaped by members of the activist organization the Vancouver Area Network of Drug Users (VANDU)...
May 22, 2018: Substance Abuse Treatment, Prevention, and Policy
https://www.readbyqxmd.com/read/29775543/native-bacterial-communities-and-listeria-monocytogenes-survival-in-soils-collected-from-the-lower-mainland-of-british-columbia-canada
#4
Justin Falardeau, Khalil Walji, Maxime Haure, Karen Fong, Gregory A Taylor, Yussanne Ma, Sean Smukler, Siyun Wang
Soil is an important reservoir for Listeria monocytogenes, a foodborne pathogen implicated in numerous produce-related outbreaks. Our objective was to (i) compare the survival of L. monocytogenes between three soils, (ii) compare the native bacterial communities across these soils, and (iii) investigate relationships between L. monocytogenes survival, native bacterial communities, and soil properties. Listeria spp. populations were monitored on PALCAM agar in three soils inoculated with L. monocytogenes (~5 x 106 CFU/g): conventionally farmed (CS), grassland transitioning to conventionally farmed (TS), and uncultivated grassland (GS)...
May 18, 2018: Canadian Journal of Microbiology
https://www.readbyqxmd.com/read/29773622/genome-sequences-of-13-isolates-of-salmonella-enterica-serovar-typhimurium-var-copenhagen-obtained-from-wild-pigeons-in-canada
#5
Bridget Xie, Andrée Ann Dupras, Marc-Olivier Duceppe, Nooshin Fattahi-Ghazi, Lawrence Goodridge, Dele Ogunremi
Pigeon-adapted strains of Salmonella enterica serovar Typhimurium var. Copenhagen phage types 2 and 99 obtained from the provinces of Alberta, British Columbia, and Ontario, Canada, were analyzed using whole-genome sequencing. All isolates contained the Salmonella virulence plasmid despite the low pathogenicity of this lineage in their avian host.
May 17, 2018: Genome Announcements
https://www.readbyqxmd.com/read/29770098/infectious-and-congenital-syphilis-in-canada-2010-2015
#6
Y Choudhri, J Miller, J Sandhu, A Leon, J Aho
Background: Syphilis is the third most commonly reported notifiable sexually transmitted infection (STI) in Canada, following chlamydia and gonorrhea, respectively. Rates of this STI have been rising rapidly in Canada since 2001. Objective: To summarize trends observed in syphilis rates for 2010 to 2015 in Canada. Methods: Laboratory-confirmed cases of infectious syphilis and early congenital syphilis were reported to the Public Health Agency of Canada by all of the Canadian provinces and territories...
February 1, 2018: Canada Communicable Disease Report, Relevé des Maladies Transmissibles Au Canada
https://www.readbyqxmd.com/read/29770083/an-outbreak-of-shiga-toxin-producing-escherichia-coli-o121-infections-associated-with-flour-canada-2016-2017-%C3%A2
#7
V Morton, J M Cheng, D Sharma, A Kearney
As of May 23, 2017, 29 cases of a new Escherichia coli O121 infection have been identified in six provinces (Alberta, British Columbia, Newfoundland and Labrador, Ontario, Quebec and Saskatchewan) linked with the consumption of uncooked flour. One additional case was identified in a U.S. resident who traveled to Canada during the exposure period. Patients' ages ranged from 2-79 years (median = 23.5 years) and 50% were female. Eight patients were hospitalized, and one developed hemolytic uremic syndrome. Because of the recent emergence of E...
July 6, 2017: Canada Communicable Disease Report, Relevé des Maladies Transmissibles Au Canada
https://www.readbyqxmd.com/read/29766659/prognosis-of-patients-with-hepatocellular-carcinoma-treated-with-sorafenib-a-comparison-of-five-models-in-a-large-canadian-database
#8
Haider H Samawi, Hao-Wen Sim, Kelvin K Chan, Mohammad A Alghamdi, Richard M Lee-Ying, Jennifer J Knox, Parneet Gill, Adriana Romagnino, Eugene Batuyong, Yoo-Joung Ko, Janine M Davies, Howard J Lim, Winson Y Cheung, Vincent C Tam
Several systems (tumor-node-metastasis [TNM], Barcelona Clinic Liver Cancer [BCLC], Okuda, Cancer of the Liver Italian Program [CLIP], and albumin-bilirubin grade [ALBI]) were developed to estimate the prognosis of patients with hepatocellular carcinoma (HCC) mostly prior to the prevalent use of sorafenib. We aimed to compare the prognostic and discriminatory power of these models in predicting survival for HCC patients treated with sorafenib and to identify independent prognostic factors for survival in this population...
May 15, 2018: Cancer Medicine
https://www.readbyqxmd.com/read/29765365/human-activity-determines-the-presence-of-integron-associated-and-antibiotic-resistance-genes-in-southwestern-british-columbia
#9
Miguel I Uyaguari-Díaz, Matthew A Croxen, Zhiyao Luo, Kirby I Cronin, Michael Chan, Waren N Baticados, Matthew J Nesbitt, Shaorong Li, Kristina M Miller, Damion Dooley, William Hsiao, Judith L Isaac-Renton, Patrick Tang, Natalie Prystajecky
The dissemination of antibiotic resistant bacteria from anthropogenic sources into the environment poses an emerging public health threat. Antibiotic resistance genes (ARGs) and gene-capturing systems such as integron-associated integrase genes ( intI ) play a key role in alterations of microbial communities and the spread of antibiotic resistant bacteria into the environment. In order to assess the effect of anthropogenic activities on watersheds in southwestern British Columbia, the presence of putative antibiotic resistance and integrase genes was analyzed in the microbiome of agricultural, urban influenced, and protected watersheds...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29764962/canadian-rheumatology-association-meeting-february-21-24-2018-introduction-abstracts-author-index
#10
(no author information available yet)
The 73rd Annual Meeting of The Canadian Rheumatology Association (CRA) was held at the JW Marriott Parq Vancouver, Vancouver, British Columbia, Canada, February 21-24, 2018. The program consisted of presentations covering original research, symposia, awards, and lectures.
May 15, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29761493/experimental-induction-of-mouthrot-in-atlantic-salmon-smolts-using-tenacibaculum-maritimum-from-western-canada
#11
K Frisch, S B Småge, C Vallestad, H Duesund, Ø J Brevik, A Klevan, R H Olsen, S T Sjaatil, D Gauthier, B Brudeseth, A Nylund
Mouthrot, or bacterial stomatitis, is a disease which mainly affects farmed Atlantic salmon, (Salmo salar, L.), smolts recently transferred into salt water in both British Columbia (BC), Canada, and Washington State, USA. It is a significant fish welfare issue which results in economic losses due to mortality and antibiotic treatments. The associated pathogen is Tenacibaculum maritimum, a bacterium which causes significant losses in many species of farmed fish worldwide. This bacterium has not been proven to be the causative agent of mouthrot in BC despite being isolated from affected Atlantic salmon...
May 14, 2018: Journal of Fish Diseases
https://www.readbyqxmd.com/read/29760260/older-patient-engagement-in-advance-care-planning-in-canadian-primary-care-practices-results-of-a-multisite-survey
#12
Michelle Howard, Carrie Bernard, Doug Klein, Amy Tan, Marissa Slaven, Doris Barwich, John J You, Gabriel Asselin, Jessica Simon, Daren K Heyland
OBJECTIVE: To assess primary care patients' engagement in advance care planning (ACP) and predictors of engagement. DESIGN: Cross-sectional survey using a revised version of a validated questionnaire. SETTING: Alberta, Ontario, and British Columbia. PARTICIPANTS: Convenience sample of 20 family practices that provided a consecutive sample of 810 patients aged 50 years and older. MAIN OUTCOME MEASURES: Engagement in ACP activities, and sociodemographic and health-related predictors of having engaged in ACP activities...
May 2018: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/29759976/missed-opportunities-for-prevention-of-vertical-hiv-transmission-in-canada-1997-2016-a-surveillance-study
#13
Ari Bitnun, Terry Lee, Jason Brophy, Lindy M Samson, Fatima Kakkar, Wendy Vaudry, Ben Tan, Deborah M Money, Joel Singer, Laura J Sauvé, Ariane Alimenti
BACKGROUND: Vertical HIV transmission has declined in Canada, but missed opportunities for prevention continue to occur. We sought to determine the adequacy, and changes over time in adequacy, of uptake of maternal and neonatal antiretroviral therapy for the prevention of vertical HIV transmission, and to determine the vertical transmission rate over time and according to adequacy of antenatal antiretroviral therapy during the combination antiretroviral therapy era in Canada. METHODS: The Canadian Perinatal HIV Surveillance Program collects data annually through retrospective chart review concerning HIV-infected women and their infants...
May 10, 2018: CMAJ Open
https://www.readbyqxmd.com/read/29757870/changing-clinical-practice-evaluation-of-implementing-recommendations-for-opportunistic-salpingectomy-in-british-columbia-and-ontario
#14
Bryn Lander, Elizabeth Wilcox, Jessica N McAlpine, Sarah J Finlayson, David G Huntsman, Dianne Miller, Gillian E Hanley
OBJECTIVE: The aim of the study was to explore the factors that contributed to the adoption of opportunistic salpingectomies (removal of fallopian at the time of hysterectomy or in lieu of tubal ligation) by gynecologic surgeons in British Columbia (where a knowledge translation initiative took place) and in Ontario (a comparator where no knowledge translation initiative took place). We aimed to understand why the knowledge translation initiative undertaken by OVCARE in British Columbia resulted in such a dramatic uptake in opportunistic salpingectomy...
May 11, 2018: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29757412/development-of-a-provincial-initiative-to-improve-glucose-control-in-critically-ill-patients
#15
Peter Dodek, Shari McKeown, Eric Young, Vinay Dhingra
Objective: To describe the development, implementation and initial evaluation of an initiative to improve glucose control in critically ill patients. Design: Glucose control in critically ill patients was chosen by critical care leaders as a target for improvement. This was an observational study to document changes in processes and measures of glucose control in each intensive care unit (ICU). ICU nurse educators were interviewed to document relevant changes between April 2012 and April 2016...
May 11, 2018: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/29757395/genotyping-and-whole-genome-sequencing-to-identify-tuberculosis-transmission-to-pediatric-patients-in-british-columbia-canada-2005-2014
#16
Jennifer L Guthrie, Andy Delli Pizzi, David Roth, Clare Kong, Danielle Jorgensen, Mabel Rodrigues, Patrick Tang, Victoria J Cook, James Johnston, Jennifer L Gardy
Background: Tuberculosis (TB) in children is often an indicator of recent transmission. Genotyping and whole genome sequencing (WGS) can enhance pediatric TB investigations by confirming or refuting transmission events. Methods: Mycobacterium tuberculosis isolates from all pediatric patients <18 years with culture-confirmed TB in British Columbia (BC) from 2005-2014 (n=49) were genotyped by MIRU-VNTR and compared to adult isolates. Genotypically clustered cases underwent WGS...
May 11, 2018: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29751256/peer-pressure-on-the-riverbank-assessing-catch-and-release-anglers-willingness-to-sanction-others-bad-behavior
#17
Meaghan L Guckian, Andy J Danylchuk, Steven J Cooke, Ezra M Markowitz
Given the well-documented impacts of angler behavior on the biological fitness of angled and released fish, optimizing the conservation value of catch-and-release angling hinges on the extent to which anglers are willing to adopt recommended best practices and refrain from harmful ones. One potentially powerful mechanism underlying adoption of best practices is the social pressure anglers can apply to one another to enforce community norms and values. Past work in other domains demonstrates that forms of interpersonal communication-including social sanctioning-can foster context-appropriate social norms and increase cooperative behavior; yet to date, little research has examined these dynamics in the context of species conservation...
May 7, 2018: Journal of Environmental Management
https://www.readbyqxmd.com/read/29746917/long-term-trajectories-of-mild-asthma-in-adulthood-and-risk-factors-of-progression
#18
Wenjia Chen, J Mark FitzGerald, Larry D Lynd, Don D Sin, Mohsen Sadatsafavi
BACKGROUND: The majority of asthma patients have mild disease. However, the clinical course of mild asthma and risk factors for progression are not well studied. OBJECTIVE: To examine the long-term trajectories of mild asthma and the effects of early-stage risk factors on the subsequent disease course. METHODS: From the administrative health data of British Columbia, Canada, we identified patients 14 to 45 years of age with newly diagnosed mild asthma between January 1997 and December 2012...
May 7, 2018: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29742035/what-do-patients-talk-about-a-qualitative-analysis-of-online-chat-sessions-with-healthcare-specialists-during-a-virtual-cardiac-rehabilitation-program
#19
Joanna Mendell, Joanna Bates, Davina Banner-Lukaris, Dan Horvat, Bindy Kang, Joel Singer, Andrew Ignaszewski, Scott A Lear
INTRODUCTION: Cardiac rehabilitation programs (CRPs) are effective at reducing cardiovascular disease (CVD) risk, yet attendance in these programs remains low due to geographic constraints. In a previously conducted randomized trial we demonstrated that a virtual CRP (vCRP) delivered over the Internet reduced risk for CVD. The current investigation has reviewed the online chat sessions between participants and healthcare providers (HCP) to describe the content of discussions during the vCRP intervention...
May 9, 2018: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/29741758/excellent-real-world-outcomes-of-adults-with-burkitt-lymphoma-treated-with-codox-m-ivac-plus-or-minus-rituximab
#20
Katie Y Zhu, Kevin W Song, Joseph M Connors, Heather Leitch, Michael J Barnett, Khaled Ramadan, Graham W Slack, Yasser Abou Mourad, Donna L Forrest, Donna E Hogge, Stephen H Nantel, Sujaatha Narayanan, Thomas J Nevill, Maryse M Power, David S Sanford, Heather J Sutherland, Tracy Tucker, Cynthia L Toze, Laurie H Sehn, Raewyn Broady, Alina S Gerrie
Treatment of Burkitt lymphoma (BL) with intensive, multi-agent chemotherapy with aggressive central nervous system (CNS) prophylaxis results in high cure rates, although no regimen is standard of care. We examined population-based survival outcomes of adults with BL treated with a modified combination of cyclophosphamide, vincristine, doxorubicin, prednisone and systemic high-dose methotrexate (MTX) (CODOX-M) with IVAC (ifosfamide, mesna, etoposide, cytarabine and intrathecal MTX) (CODOX-M/IVAC) ± rituximab over a 15-year period in British Columbia...
May 9, 2018: British Journal of Haematology
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