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Hongping Xiang, Yingying Tang, Suyun Zhang, Zhangzhen He
The electronic structure and magnetic properties of the quasi-1D transition-metal borates PbMBO4 (M  =  Ti, V, Cr, Mn, Fe, Co) have been investigated by density functional theory, including electronic correlation. The results evidence PbCrBO4 and PbFeBO4 as antiferromagnetic (AFM) semiconductors (intra-chain AFM and inter-chain FM) and PbMnBO4 as a ferromagnetic (FM) semiconductor (both intra- and inter-chain FM) in accordance with experimental observations. For non-synthesized PbTiBO4, PbVBO4, and PbCoBO4, the ground-state magnetic structures are paramagnetic, FM, and paramagnetic, respectively...
July 13, 2016: Journal of Physics. Condensed Matter: An Institute of Physics Journal
Jae Sang Heo, Jeong-Wan Jo, Jingu Kang, Chan-Yong Jeong, Hu Young Jeong, Sung Kyu Kim, Kwanpyo Kim, Hyuck-In Kwon, Jaekyun Kim, Yong-Hoon Kim, Myung-Gil Kim, Sung Kyu Park
The low-temperature electrical passivation of an amorphous oxide semiconductor (AOS) thin-film transistor (TFT) is achieved by a deep ultraviolet (DUV) light irradiation-water treatment-DUV irradiation (DWD) method. The water treatment of the first DUV-annealed amorphous indium-gallium-zinc-oxide (a-IGZO) thin film is likely to induce the preferred adsorption of water molecules at the oxygen vacancies and leads to subsequent hydroxide formation in the bulk a-IGZO films. Although the water treatment initially degraded the electrical performance of the a-IGZO TFTs, the second DUV irradiation on the water-treated devices may enable a more complete metal-oxygen-metal lattice formation while maintaining low oxygen vacancies in the oxide films...
April 27, 2016: ACS Applied Materials & Interfaces
Maoyuan Liu, Aurélie Jacob, Clemens Schmetterer, Patrick J Masset, Louis Hennet, Henry E Fischer, Jad Kozaily, Sandro Jahn, Angus Gray-Weale
Calcium aluminosilicate CaO-Al2O3-SiO2 (CAS) melts with compositions (CaO-SiO2)(x)(Al2O3)(1-x) for x  <  0.5 and (Al2O3)(x)(SiO2)(1-x) for x ≥ 0.5 are studied using neutron diffraction with aerodynamic levitation and density functional theory molecular dynamics modelling. Simulated structure factors are found to be in good agreement with experimental structure factors. Local atomic structures from simulations reveal the role of calcium cations as a network modifier, and aluminium cations as a non-tetrahedral network former...
April 6, 2016: Journal of Physics. Condensed Matter: An Institute of Physics Journal
Moamen M O M Aly, Yasser Abo-Madyan, Lennart Jahnke, Frederik Wenz, Gerhard Glatting
PURPOSE: A method is presented to radiobiologically compare sequential (SEQ) and simultaneously integrated boost (SIB) breast radiotherapy. METHODS: The method is based on identically prescribed biologically effective dose (iso-BED) which was achieved by different prescribed doses due to different fractionation schemes. It is performed by converting the calculated three-dimensional dose distribution to the corresponding BED distribution taking into consideration the different number of fractions for generic α/β ratios...
2016: Radiation Oncology
L M A Van Loon, M O M Van De Ven, K T M Van Doesum, C M H Hosman, C L M Witteman
BACKGROUND: Children of parents with mental illness have an elevated risk of developing a range of mental health and psychosocial problems. Yet many of these children remain mentally healthy. OBJECTIVE: The present study aimed to get insight into factors that protect these children from developing internalizing and externalizing problems. METHODS: Several possible individual, parent-child, and family protective factors were examined cross-sectionally and longitudinally in a sample of 112 adolescents...
2015: Child & Youth Care Forum
N Lytvynenko, S Cherenko, Y Feschenko, M Pogrebna, Y Senko, A Barbova, M Manzi, O Denisiuk, A Ramsay, R Zachariah
SETTING: A tertiary care facility in Ukraine, a high multi- and extensively drug-resistant tuberculosis (MDR/XDR-TB) burden country. OBJECTIVES: To assess the management and treatment outcomes of MDR, pre-XDR-TB and XDR-TB. DESIGN: Cohort study using programme data, 2006-2011. RESULTS: Of 484 individuals with drug-resistant TB, 217 (45%) had MDR-, 153 (32%) pre-XDR- and 114 (24%) XDR-TB. Of all resistant types completing the intensive phase of treatment, 322 (67%) were alive and had culture converted...
October 21, 2014: Public Health Action
O Dolgusev, N Obevzenco, O Padalco, S Pankrushev, A Ramsay, R Van den Bergh, M Manzi, O Denisiuk, R Zachariah
This cohort study assessed drug susceptibility testing (DST) patterns and associated treatment outcomes from Transnistria, Moldova, from 2009 to 2012. Of 1089 newly registered tuberculosis (TB) patients with available DST results, 556 (51%) had some form of drug resistance, while 369 (34%) had multidrug-resistant TB (MDR-TB). There were four cases of extensively drug-resistant TB. MDR-TB patients had poor treatment success (45%); human immunodeficiency virus positivity and a history of incarceration were associated with an unfavourable treatment outcome...
October 21, 2014: Public Health Action
K Davtyan, R Zachariah, H Davtyan, A Ramsay, O Denisiuk, M Manzi, M Khogali, R Van den Bergh, A Hayrapetyan, M Dara
We assessed the performance of decentralised tuberculosis (TB) out-patient centres in tuberculosis (TB) case notification and treatment success in Armenia. An average threshold case notification of ⩾37/100 000 was seen in centres that had higher numbers of presumptive TB patients, where more TB was diagnosed by in-patient facilities and where TB contacts were examined. The number of doctors and/or TB specialists at centres did not influence case notification. Onsite smear microscopy was significantly associated with a treatment success rate of ⩾85% for new TB patients...
October 21, 2014: Public Health Action
Jesse T Jedial, Aminu Shittu, Faruk M Tambuwal, Mikail B Abubakar, Muhammed K Garba, Jacob P Kwaga, Folorunso O Fasina
OBJECTIVES: Escherichia coli are an important group of bacteria in the normal gastrointestinal system but can sometimes cause infections in domestic animals and man. Donkeys are routinely used as multipurpose animal but details of burdens of potentially infectious bacteria associated with it are limited. The prevalence and associations between intestinal shedding of E. coli O157 and animal characteristics and management factors were studied among 240 randomly selected working donkeys in north-western Nigeria...
2015: Veterinary Record Open
C Freitag, C Noble, J Fritzsche, F Persson, M Reiter-Schad, A N Nilsson, A Granéli, T Ambjörnsson, K U Mir, J O Tegenfeldt
The contiguity and phase of sequence information are intrinsic to obtain complete understanding of the genome and its relationship to phenotype. We report the fabrication and application of a novel nanochannel design that folds megabase lengths of genomic DNA into a systematic back-and-forth meandering path. Such meandering nanochannels enabled us to visualize the complete 5.7 Mbp (1 mm) stained DNA length of a Schizosaccharomyces pombe chromosome in a single frame of a CCD. We were able to hold the DNA in situ while implementing partial denaturation to obtain a barcode pattern that we could match to a reference map using the Poland-Scheraga model for DNA melting...
July 2015: Biomicrofluidics
R Libé, I Borget, C L Ronchi, B Zaggia, M Kroiss, T Kerkhofs, J Bertherat, M Volante, M Quinkler, O Chabre, M Bala, A Tabarin, F Beuschlein, D Vezzosi, T Deutschbein, F Borson-Chazot, I Hermsen, A Stell, C Fottner, S Leboulleux, S Hahner, M Mannelli, A Berruti, H Haak, M Terzolo, M Fassnacht, E Baudin
BACKGROUND: The clinical course of advanced adrenocortical carcinoma (ACC) is heterogeneous. Our study aimed primarily to refine and make headway in the prognostic stratification of advanced ACC. PATIENTS AND METHODS: Patients with advanced ENSAT ACC (stage III or stage IV) at diagnosis registered between 2000 and 2009 in the ENSAT database were enrolled. The primary end point was overall survival (OS). Parameters of potential prognostic relevance were selected...
October 2015: Annals of Oncology: Official Journal of the European Society for Medical Oncology
Corrie M Whisner, Bridget E Young, Frank R Witter, Zena Leah Harris, Ruth A Queenan, Elizabeth M Cooper, Kimberly O O'Brien
No abstract text is available yet for this article.
October 2015: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
V V Troitskaia, E N Parovichnikova, A N Sokolov, A V Kokhno, L A Kuz'mina, D S Badmazhapova, Z T Fidarova, O A Gavrilina, A A Sidorova, G M Galstian, S A Kesel'man, T V Gaponova, V S Galuziak, S K Kravchenko, E O Gribanova, V G Savchenko
AIM: To evaluate the efficiency of the treatment policy for patients with acute myeloid leukemia (AML) and hyperleukocytosis (HL), which is aimed at preventing rapid hypercytolysis and massive tumor lysis (cytolysis) syndrome and/or at reducing the degree of the latter at the start of induction polychemotherapy. SUBJECTS AND METHODS: In 2010 to 2014, the Hematology Research Center, Ministry of Health of Russia, treated 92 patients with AML, out of them 18 patients were found to have white blood cell counts of 100 to 408-10(9)/1 (median, 130-10(9)/l) at the onset of the disease...
2015: Terapevticheskiĭ Arkhiv
S V Semochkin, T N Tolstykh, N V Arkhipova, V L Ivanova, O V Kliueva, V V Lunin, E N Misiurina, M V Tumanova, N K Khuazheva
AIM: To estimate the incidence of acute myeloid leukemias (AML) in Moscow adults and to evaluate the efficiency of their treatment. SUBJECTS AND METHODS: Data on Moscow residents who were first diagnosed with AML in 2010 were retrospectively collected. The efficiency of their treatment was evaluated from the rates of complete remissions (CR), recurrences, deaths, and 4-year overall (OS) and relapse-free survival (RFS). The data as of September 1, 2013, were analyzed...
2015: Terapevticheskiĭ Arkhiv
E N Parovichnikova, L A Kuz'mina, L P Mendeleeva, G A Kliasova, V V Troitskaia, A N Sokolov, Z Kh Akhmerzaeva, S K Kravchenko, E O Gribanova, E E Zvonkov, S N Bondarenko, O Iu Baranova, T V Ryl'tsova, L V Gavrilova, E E Zinina, A S Pristupa, T S Kaporskaia, N V Minaeva, O S Samoiĭova, T S Konstantinova, V A Lapin, K D Kaplanov, I V Kriuchkova, A S Nizamutdinova, A V Klimovich, E A Borisenkova, V I Moskov, T V Gaponova, T V Obukhova, I V Gal'tseva, M A Rusinov, S M Kulikov, V G Savchenko
AIM: To analyze the efficiency of the ALL-2009 protocol ( NCT01 193933) in patients with T-cell leukemias, particularly the role of autologous hematopoietic stem cell transplantation (auto-HSCT) after non-myeloablative BEAM conditioning, followed by maintenance therapy. SUBJECTS AND METHODS: Since 2009, the ALL-2009 study has enrolled 90 patients with T-cell acute lymphoblastic leukemia (T-ALL), the treatment results were assessed in 86 patients: 6 and 28 patients underwent allogeneic HSCT and auto-HSCT, respectively...
2015: Terapevticheskiĭ Arkhiv
S K Choi, Y O Hong, W M Lee, E K Kim, J E Joo, D W Kim, H Lee
OBJECTIVE: To investigate the expression of PI3K-p110α, pAkt, PTEN, the signaling molecules from PI3K/Akt signaling pathway, DJ-1, an oncoprotein and HSP90a, a molecular chaperone, and their correlation in uterine cervical neoplasia, in order to elucidate their role in cervical carcinogenesis. MATERIALS AND METHODS: Using immunohistochemistry, the authors analyzed the expression of PI3K-p110α, pAkt, PTEN, DJ-1 and HSP90α, and their correlation in ten normal tissues, cervical intraepithelial neoplasia (CIN) including 30 CIN1 and 31 CIN3, and 33 cases of invasive squamous cell carcinoma (SCC)...
2015: European Journal of Gynaecological Oncology
Qiao-han Wang, Xiao-lin Yang, Wei Xiao, Zhen-zhong Wang, Gang Ding, Wen-zhe Huang, Zhong-lin Yang
According to ICH, Chinese Pharmacopoeia and supplementary requirements on the separation and purification of herbal extract with macroporous adsorption resin by SFDA, hexane, acetidine, ethanol, benzene, methyl-benzene, o-xylene, m-xylene, p-xylene, styrene, diethyl-benzene and divinyl-benzene of residual organic solvents and macroporous resin residues in Akebia saponin D were determined by headspace capillary GC. Eleven residues in Akebia saponin D were completely separated on DB-wax column, with FID detector, high purity nitrogen as the carry gases...
May 2015: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
Jian-qun Liu, Jian Liu, Wei Jiang, Guo-yue Zhong
The quality control method and standard were established to control the quality of Pteris multifida in this paper. The tests of water content, total ash, acid-unsoluble ash and ethanol-soluble extractives of P. multifida were carried out according to the methods recorded in appendix of Chinese Pharmacopeia (2010 edition, volume 1) . The TLC method was established by using rhoifolin as references, and a mixture of CHCl3 -MeOH-HAc (6: 1: 1) as the developing solvent system on GF254 thin layer plate. The contents of rhoifolin was determined by HPLC on a Diamonsil C18 (4...
May 2015: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
S O Sosnovskiĭ, V Kh Kheĭfets, O F Kagan
The effectiveness of overactive bladder treatment with M-cholinoblocker solifenacin (Vesicare) as monotherapy and in combination with α1-andrenoblocker terazosin (Setegis) or bladdrer training in elderly patients was evaluated. The results of 12 weeks treatment in all treatment modality groups were comparable. Use of solifenacin in combination with α1-andrenoblocker in comparison to solifenacin monotherapy resulted in longer symptoms remission.
2015: Advances in Gerontology, Uspekhi Gerontologii
V N Manskikh, O S Gancharova, E A Novikov, E Iu Kondratiuk, V P Skulachev, M P Moshkin
The mole vole (Ellobius talpinus (Pallas), Rodentia) is the object of interest for cytogenetics, ecology and gerontology research, peculiarly because of partial similarity of this animal to the unique long-living rodent, mole rat. In this work, the mole vole has been found to have very specific spectrum of tumors and non-tumor pathologies which vastly differs from pathological lesions spectrum in mole rat, laboratory mouse, rat and hamster. Mole voles had relatively small tumor incidence (9% totally in the observed population and 16% in animals dead after the achievement of the first tumor development age) and long minimal span of tumor latency (549 days) that is why this species could be categorized as cancer-resistant in compare to laboratory rodents (mice, rats, hamsters)...
2015: Advances in Gerontology, Uspekhi Gerontologii
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