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https://www.readbyqxmd.com/read/29762067/parenting-and-cyberbullying-across-adolescence
#1
Jessica D Zurcher, Hailey G Holmgren, Sarah M Coyne, Christopher P Barlett, Chongming Yang
Cyberbullying perpetration continues to be a prevalent and harmful phenomenon. Despite the recent wealth of studies that examine cyberbullying frequency, further research is needed to investigate protective factors or variables that decrease the likelihood of engaging in cyberbullying perpetration. Past work has identified certain types of parenting as a potential protective factor against adolescent cyberbullying perpetration; however, there is a paucity of research testing these relations over time. This study explores parenting during early adolescence as predicting attitudes and behaviors associated with cyberbullying in late adolescence...
May 2018: Cyberpsychology, Behavior and Social Networking
https://www.readbyqxmd.com/read/29743396/-congenital-factor-v-and-factor-viii-deficiency-discovered-in-an-elderly-patient-with-abnormal-bleeding-after-trauma
#2
Yoshiyuki Ogawa, Kunio Yanagisawa, Yuri Uchiyama, Akira Matsumoto, Madoka Inoue, Kohtaro Toyama, Yuri Miyazawa, Naomichi Matsumoto, Hiroshi Handa
Congenital combined deficiency of coagulation factor V (FV) and factor VIII (FVIII) (F5F8D) is a rare autosomal recessive bleeding disorder caused by mutations in lectin mannose-binding type 1 (LMAN1) or multiple coagulation factor deficiency 2 (MCFD2) encoding chaperone molecules involved in the intracellular transport of FV and FVIII. Here, we report a case of F5F8D in an elderly patient diagnosed with hematoma after a right thigh injury. A 71-year-old male had a history of abnormal bleeding after tooth extraction and cholecystectomy...
2018: [Rinshō Ketsueki] the Japanese Journal of Clinical Hematology
https://www.readbyqxmd.com/read/29742287/a-mobile-health-technology-enabled-home-based-intervention-to-treat-frailty-in-adult-lung-transplant-candidates-a-pilot-study
#3
Jonathan P Singer, Allison Soong, Alan Bruun, Ayana Bracha, Greg Chin, Steven R Hays, Jasleen Kukreja, Julia Rigler, Jeff A Golden, John R Greenland, Chris Garvey
BACKGROUND: Frailty is prevalent in lung transplant candidates (LTC) and is associated with waitlist delisting or death. We performed a pilot study to assess the safety and feasibility of a home-based, mobile-health technology facilitated intervention to treat frailty in LTC. METHODS: We performed an 8-week, non-randomized, home-based exercise and nutrition intervention in LTC with Short Physical Performance Battery (SPPB) frailty scores of ≤11. The intervention utilized a customized, mobile device application ("app") enabling monitoring and progression of the intervention in real-time...
May 9, 2018: Clinical Transplantation
https://www.readbyqxmd.com/read/29739232/comparison-of-the-coagulation-effect-achieved-by-octaplaslg-versus-fresh-frozen-plasma-in-pediatric-cardiac-surgical-patients
#4
Amanpreet S Kalsi, Omar Al-Azzawi, Ravi Gill
OctaplasLG is indicated for use in patients undergoing cardiac surgery who require replacement of multiple clotting factors. The use of OctaplasLG over single-donor fresh frozen plasma (FFP) may have beneficial effects when considering the transmission of enveloped viruses. Additionally, it has the potential for fewer adverse reactions, reduced disease transmission, and a more homogenous coagulation factor composition. However, its efficacy and safety have not yet been evaluated in the pediatric population...
January 1, 2018: Clinical and Applied Thrombosis/hemostasis
https://www.readbyqxmd.com/read/29713955/successful-hemostatic-management-of-major-surgery-for-cervical-spondylotic-myelopathy-in-a-patient-with-severe-factor-xi-deficiency
#5
Yoshiyuki Ogawa, Kunio Yanagisawa, Yuri Uchiyama, Naoki Akashi, Tokue Mieda, Haku Iizuka, Madoka Inoue, Reiko Shizuka, Masami Murakami, Naomichi Matsumoto, Hiroshi Handa
Factor XI deficiency (FXID) is a rare bleeding disorder caused by mutations in the F11 gene. Spontaneous bleeding in patients with factor XI deficiency is rare, but major bleeding may occur after surgery or trauma. The basic method for hemostatic treatment is replacement of the missing factor using FXI concentrate or fresh frozen plasma (FFP). We report the case of a 72-year-old male with severe FXID who underwent a laminoplasty under sufficient, but minimal, FFP transfusion. Through detailed monitoring of activated partial thromboplastin time (APTT) and FXI activity at the perioperative period, we succeeded in hemostatic management of major surgery without significant blood loss and fluid overload...
April 30, 2018: International Journal of Hematology
https://www.readbyqxmd.com/read/29701555/stereotactic-radiosurgery-for-trigeminal-neuralgia-a-systematic-review
#6
Constantin Tuleasca, Jean Régis, Arjun Sahgal, Antonio De Salles, Motohiro Hayashi, Lijun Ma, Roberto Martínez-Álvarez, Ian Paddick, Samuel Ryu, Ben J Slotman, Marc Levivier
OBJECTIVES The aims of this systematic review are to provide an objective summary of the published literature specific to the treatment of classical trigeminal neuralgia with stereotactic radiosurgery (RS) and to develop consensus guideline recommendations for the use of RS, as endorsed by the International Society of Stereotactic Radiosurgery (ISRS). METHODS The authors performed a systematic review of the English-language literature from 1951 up to December 2015 using the Embase, PubMed, and MEDLINE databases...
April 27, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29687444/thrombin-generation-potential-and-clot-forming-capacity-of-thawed-fresh-frozen-plasma-plasma-frozen-within-24-h-and-solvent-detergent-treated-plasma-octaplaslg-%C3%A2-during-5-day-storage-at-1-6%C3%A2-c
#7
A Heger, A Neisser-Svae, L Trawnicek, D Triulzi
To enable rapid availability of plasma in emergency situations, the shelf-life of thawed fresh-frozen plasma (FFP) has been extended from 24 h to 5 days. The aim of this study was to evaluate the thrombin generation (TG) potential and clot-forming ability during 5 days of refrigerated storage of thawed FFP, plasma frozen within 24 h and solvent/detergent-treated plasma octaplasLG® . During storage for 5 days, TG capacity decreased significantly over time, and rotational thromboelastometry showed significantly prolonged clotting times...
April 23, 2018: Vox Sanguinis
https://www.readbyqxmd.com/read/29681897/population-genetic-structure-of-listeria-monocytogenes-strains-isolated-from-the-pig-and-pork-production-chain-in-france
#8
Benjamin Félix, Carole Feurer, Aurelien Maillet, Laurent Guillier, Evelyne Boscher, Annaëlle Kerouanton, Martine Denis, Sophie Roussel
Listeria monocytogenes is an ubiquitous pathogenic bacterium, transmissible to humans through the consumption of contaminated food. The pork production sector has been hit hard by a series of L. monocytogenes -related food poisoning outbreaks in France. An overview of the diversity of strains circulating at all levels of the pork production chain, from pig farming (PF) to finished food products (FFP), is needed to identify the contamination routes and improve food safety. Until now, no typing data has been available on strains isolated across the entire pig and pork production chain...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29667786/frailty-phenotypes-and-mortality-after-lung-transplantation-a-prospective-cohort-study
#9
Jonathan P Singer, Joshua M Diamond, Michaela R Anderson, Patricia P Katz, Ken Covinsky, Michelle Oyster, Tatiana Blue, Allison Soong, Laurel Kalman, Pavan Shrestha, Selim M Arcasoy, John R Greenland, Lori Shah, Jasleen Kukreja, Nancy P Blumenthal, Imaani Easthausen, Jeffrey A Golden, Amika McBurnie, Ed Cantu, Joshua Sonett, Steven Hays, Hilary Robbins, Kashif Raza, Matthew Bacchetta, Rupal J Shah, Frank D'Ovidio, Aida Venado, Jason D Christie, David J Lederer
Frailty is associated with increased mortality among lung transplant candidates. We sought to determine the association between frailty, as measured by the Short Physical Performance Battery (SPPB), and mortality after lung transplantation. In a multicenter prospective cohort study of adults who underwent lung transplantation, preoperative frailty was assessed with the SPPB (n = 318) and, in a secondary analysis, the Fried Frailty Phenotype (FFP; n = 299). We tested the association between preoperative frailty and mortality following lung transplantation with propensity score-adjusted Cox models...
April 18, 2018: American Journal of Transplantation
https://www.readbyqxmd.com/read/29664892/the-role-of-4-factor-prothrombin-complex-concentrate-4-pcc-in-coagulopathy-of-trauma-a-propensity-matched-analysis
#10
Faisal Jehan, Hassan Aziz, Terence O'Keeffe, Muhammad Khan, El Rasheid Zakaria, Mohammad Hamidi, Muhammad Zeeshan, Narong Kulvatunyou, Bellal Joseph
INTRODUCTION: Coagulopathy is a common complication after severe trauma. The efficacy of 4-factor Prothrombin Complex Concentrate (4-PCC) as an adjunct to FFP in reversal of coagulopathy of trauma has not been studied. The aim of our study is to compare 4-PCC+FFP vs. FPP alone for the treatment of COT. METHODS: We reviewed all trauma patients >18y who received PCC+FFP or FFP alone at our Level I trauma center from 2015-16. We excluded patients on preinjury oral anticoagulants...
April 16, 2018: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29661282/impact-of-fresh-frozen-plasma-transfusion-on-postoperative-inflammation-and-prognosis-of-colorectal-liver-metastases
#11
Yuichi Nakaseko, Koichiro Haruki, Hiroaki Shiba, Takashi Horiuchi, Nobuhiro Saito, Taro Sakamoto, Takeshi Gocho, Katsuhiko Yanaga
BACKGROUND: Blood transfusion has been reported to be associated with immunomodulation and poor oncologic outcomes in several malignancies. The aim of the study is to investigate the influence of the use of fresh frozen plasma (FFP) on long-term outcomes in patients with colorectal liver metastases (CRLM) after hepatic resection. MATERIALS AND METHODS: The study comprised 127 patients who had undergone first hepatic resection for CRLM between April 2000 and December 2013...
June 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29660186/influence-of-prenatal-diagnosis-of-abnormally-invasive-placenta-on-maternal-outcome-a-systematic-review-and-meta-analysis
#12
REVIEW
Danilo Buca, Marco Liberati, Giuseppe Calì, Francesco Forlani, Claudia Caisutti, Maria Elena Flacco, Lamberto Manzoli, Alessandra Familiari, Giovanni Scambia, Francesco D'Antonio
OBJECTIVES: The aim of this systematic review was to ascertain the impact of prenatal diagnosis on surgical outcome of women affected by AIP. METHODS: Medline, Embase, CINAHL and Cochrane databases were searched. The outcomes observed were: gestational age at birth (weeks), amount of blood loss (l), units of red blood cells (RBC), platelets (PLT) and fresh frozen plasma (FFP) transfused, length of stay in hospital and in intensive care unit (days), urinary tract injuries and infection...
April 16, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29656684/nationwide-survey-of-severe-postpartum-haemorrhage-in-japan-an-exploratory-study-using-the-national-database-of-health-insurance-claims
#13
Mai Sato, Eiji Kondoh, Tomohide Iwao, Shusuke Hiragi, Kazuya Okamoto, Hiroshi Tamura, Haruta Mogami, Yoshitsugu Chigusa, Tomohiro Kuroda, Masaki Mandai, Ikuo Konishi, Genta Kato
AIM: The aim of this study was to investigate epidemiological and clinical aspects of severe postpartum haemorrhage (PPH) in Japan. METHODS: We used national health insurance claims from 2011 to 2014 provided by the Ministry of Health, Labour and Welfare. The data included randomly selected claims that covered 10% of all inpatients in October, a so-called sampling dataset (covering 1/120 inpatients per year). We extracted claims for transfused blood, and further narrowed down the claims by names of diseases linked to PPH...
April 15, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29622392/comparison-of-drug-administration-logistics-between-prothrombin-complex-concentrates-and-plasma-in-the-emergency-department
#14
Sumaiah J Alarfaj, Daniel H Jarrell, Asad E Patanwala
BACKGROUND: Prothrombin complex concentrate (PCC) is used as an alternative to fresh frozen plasma (FFP) for emergency bleeding. The primary objective of this study was to compare the time from order to start of administration between 3-factor PCC (PCC3), 4-factor (PCC4), and FFP in the emergency department (ED). The secondary objective was to evaluate the effect of an ED pharmacist on time to administration of PCCs. METHODS: This was a single center three-arm retrospective cohort study...
March 24, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29573937/comparison-of-local-injection-of-fresh-frozen-plasma-to-traditional-methods-of-hemostasis-in-minimally-invasive-procedures
#15
John Haaga, Shiraz Rahim, Victor Kondray, Jon Davidson, Indravadan Patel, Dean Nakamoto
RATIONALE AND OBJECTIVES: To evaluate different techniques for reducing hemorrhagic complications in coagulopathic patients with elevated international normalized ratio having an image-guided percutaneous invasive procedure; techniques included systemic transfusion of fresh frozen plasma (FFP), local injection of FFP, percutaneous injection of gelatin sponge, and percutaneous placements of angiographic coils. MATERIALS AND METHODS: Retrospective review of 232 consecutive patients with known coagulopathy undergoing image-guided minimally invasive procedures were selected...
March 22, 2018: Academic Radiology
https://www.readbyqxmd.com/read/29563677/effect-of-plasma-component-transfusion-on-conventional-coagulation-screening-tests
#16
Manish Raturi, Shamee Shastry, Mohandoss Murugesan, Poornima B Baliga, Kalyana Chakravarthy
BACKGROUND: Conventional coagulation screening tests such as Prothrombin time, International normalized ratio (INR) and activated partial thromboplastin time are often used to predict bleeding in various clinical situations. We aimed to observe the effect of Fresh-frozen plasma (FFP) on these parameters. Methods: Patients' demographics, pre- and post-transfusion coagulation parameters were noted to assess the level of correction. The magnitude of improvement in INR was determined using the formula given by Holland and Brooks...
January 2018: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/29536603/biosimilar-vs-originator-insulins-systematic-review-and-meta-analysis
#17
Tomohide Yamada, Ryuichi Kamata, Kotomi Ishinohachi, Nobuhiro Shojima, Sophia Ananiadou, Hisashi Nom, Toshimasa Yamauchi, Takashi Kadowaki
Biosimilar insulins have expanded the treatment options for diabetes. We compared the clinical efficacy and safety of biosimilar insulins with those of originator insulins by conducting a meta-analysis. A random-effects meta-analysis was performed on randomized controlled trials comparing biosimilar and originator insulins in adults with diabetes. Studies were obtained by searching electronic databases up to December 2017. Ten trials, in a total of 4935 patients, were assessed (2 trials each on LY2963016, MK-1293, Mylan's insulin glargine and SAR342434, and 1 trial each on FFP-112 and Basalog)...
March 14, 2018: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/29530808/biogenic-synthesis-of-copper-nanoparticles-by-natural-polysaccharides-and-pleurotus-ostreatus-fermented-fenugreek-using-gamma-rays-with-antioxidant-and-antimicrobial-potential-towards-some-wound-pathogens
#18
Ahmed I El-Batal, Nawal E Al-Hazmi, Farag M Mosallam, Gharieb S El-Sayyad
Mono-dispersed copper nanoparticles (CuNPs) were constructed using cheap polysaccharides (citrus pectin, chitosan, and sodium alginate), and by appropriating aqueous fermented fenugreek powder (FFP) under the action of Pleurotus ostreatus (as reducing and preserving means), through the influence of gamma irradiation. The synthesized CuNPs are described by UV-Vis. spectroscopy TEM, DLS, XRD, and FT-IR. XRD study of the CuNPs confirmed the generation of metallic CuNPs. The nucleation and the production mechanism of CuNPs are moreover explained...
March 9, 2018: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29502974/the-effect-of-fibrinogen-concentrate-and-fresh-frozen-plasma-on-the-outcome-of-patients-with-acute-traumatic-coagulopathy-a-quasi-experimental-study
#19
Ehsan Akbari, Saeed Safari, Hamidreza Hatamabadi
INTRODUCTION: The debate on replacing coagulation factors and its effect on the final outcome of the patients with acute traumatic coagulopathy (ATC) in need of transfusion is still ongoing. Therefore, the present study is designed with the aim of comparing the outcome of patients with acute traumatic coagulopathies receiving fibrinogen and fresh frozen plasma (FFP). METHODS: In this quasi-experimental randomized controlled study, patients with severe blunt trauma (ISS>16) and in need of packed cells transfusion were divided into 3 groups of receiving fibrinogen, receiving FFP, and control, and their final outcome was compared...
February 22, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29477943/the-use-of-emergency-apheresis-in-the-management-of-plasma-cell-disorders
#20
REVIEW
Sevgi Kalayoglu-Besisik
Hyperviscosity syndrome (HVS) develops most commonly in Waldenström's macroglobulinemia (WM) and multiple myeloma (MM). Plasmapheresis is the immediate therapy and very effective at relieving symptoms by removing paraprotein. The most commonly used replacement fluid is 4%-5% human albumin in physiologic saline. FFP may be used in patients with coagulation abnormalities. Plasmapheresis should be continued until acute symptoms abate. Hyperviscosity impairs the circulation in the retina and causes hemorrhages around the small retinal vessels...
February 2018: Transfusion and Apheresis Science
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