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https://www.readbyqxmd.com/read/28633890/universal-measles-mumps-rubella-vaccination-to-new-recruits-and-the-incidence-of-mumps-in-the-military
#1
Jong Youn Moon, Jaehun Jung, Kyungmin Huh
In response to the resurgence of mumps, the Korean Armed Forces started the measles-mumps-rubella (MMR) vaccination to all new recruits regardless of prior vaccination history. We evaluated the effectiveness of the vaccination by comparing the incidence between the military and civilian populations before and after implementation of the new policy. The standardized incidence ratio of mumps in the military was 7.06 in the prevaccine period, which declined to 0.96 in the postvaccine period. Vaccine effectiveness was estimated at 86...
June 17, 2017: Vaccine
https://www.readbyqxmd.com/read/28633302/mumps-clinical-diagnostic-uncertainty
#2
Fabio Magurano, Melissa Baggieri, Antonella Marchi, Paola Bucci, Giovanni Rezza, Loredana Nicoletti
During recent years, various mumps outbreaks have occurred among populations vaccinated for mumps worldwide. In Italy, improving routine coverage with two doses of measles, mumps and rubella (MMR) vaccine is one of the key strategies to eliminate measles and rubella. To monitor the effect of the vaccination programme on the population, the surveillance of these vaccine-preventable diseases has been implemented. This provided the opportunity to evaluate the accuracy of the clinical diagnosis of those diseases, including mumps...
June 12, 2017: European Journal of Public Health
https://www.readbyqxmd.com/read/28631171/qualitative-assessment-of-vaccination-hesitancy-among-members-of-the-apostolic-church-of-zimbabwe-a-case-study
#3
Z Machekanyanga, S Ndiaye, R Gerede, K Chindedza, C Chigodo, M E Shibeshi, J Goodson, F Daniel, L Zimmerman, R Kaiser
Vaccine hesitancy or lack of confidence in vaccines is considered a threat to the success of vaccination programs. The rise and spread of measles outbreaks in southern Africa in 2009-2010 were linked to objections among Apostolic Church members, estimated at about 3.5 million in Zimbabwe as of 2014. To inform planning of interventions for a measles-rubella vaccination campaign, we conducted an assessment of the factors contributing to vaccine hesitancy using data from various stakeholders. Among nine districts in three regions of Zimbabwe, we collected data on religious attitudes toward, and perceptions of, vaccines through focus group discussions with health workers serving Apostolic communities and members of the National Expanded Programme on Immunization; semi-structured interviews with religious leaders; and open-ended questions in structured interviews with Apostolic parents/caregivers...
June 19, 2017: Journal of Religion and Health
https://www.readbyqxmd.com/read/28624983/how-to-increase-vaccination-acceptance-among-apostolic-communities-quantitative-results-from-an-assessment-in-three-provinces-in-zimbabwe
#4
Regina Gerede, Zorodzai Machekanyanga, Serigne Ndiaye, Kenneth Chindedza, Colline Chigodo, Messeret E Shibeshi, James Goodson, Fussum Daniel, Reinhard Kaiser
A worldwide increasing trend toward vaccine hesitancy has been reported. Measles outbreaks in southern Africa in 2009-2010 were linked to objections originating from Apostolic gatherings. Founded in Zimbabwe in the 1950s, the Apostolic church has built up a large number of followers with an estimated 3.5 million in Zimbabwe in 2014. To inform planning of interventions for the 2015 measles-rubella vaccination campaign, we assessed vaccination status and knowledge, attitudes and practices among purposive samples of Apostolic caregivers in three districts each in Harare City, Manicaland and Matabeleland South in Zimbabwe...
June 17, 2017: Journal of Religion and Health
https://www.readbyqxmd.com/read/28622418/severe-apparently-isolated-fetal-ventriculomegaly-and-neurodevelopmental-outcome
#5
Mathilde Letouzey, Alexandra Chadie, Marie Brasseur-Daudruy, François Proust, Eric Verspyck, Pascal Boileau, Stéphane Marret
OBJECTIVE: To assess the neurodevelopmental outcome of children with a prenatal diagnosis of apparently isolated severe ventriculomegaly (SVM). METHOD: Retrospective cohort study from 1994 to 2011. We included fetuses with unilateral or bilateral ventriculomegaly equal to or greater than 15 mm at prenatal ultrasound and confirmed by Magnetic Resonance Imaging, whose parents chose continuation of pregnancy past 22 weeks, and with no associated findings at diagnosis (i...
June 16, 2017: Prenatal Diagnosis
https://www.readbyqxmd.com/read/28617262/mmr-vaccine-in-the-postpartum-does-not-expose-seronegative-women-to-untoward-effects
#6
Enrico Finale, Giuliana Leonardi, Gaetano Auletta, Roberta Amadori, Chiara Saglietti, Leonardo Pagani, Andrea Guala
BACKGROUND: The aim of this study was to assess whether rubella vaccination immediately after delivery could expose seronegative women to specific untoward effects. METHODS: 163 rubella-seronegative women received Measles-Mumps-Rubella (MMR) vaccine in the immediate postpartum period; they were evaluated at one month and at three months thereafter through telephone interviews. As controls, we matched 163 rubella-seropositive women, who might experience similar symptoms for any reason in the same timeframe...
April 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28615701/revisiting-zika-and-rubella
#7
Adolfo Martinez-Palomo
Three months after the World Health Organization declared the epidemic of Zika virus infections to be a Public Health Emergency of International Concern, we can look back at what we have learned and prospects for controlling the disease. Although Zika virus infections may explain many cases of brain damage in newborns, it may not be the only cause. We need a clear association between confirmed cases of Zika infections in pregnant women and microcephaly in newborns. Until we reach a firm conclusion, past experience with another virus that causes damage to newborns offers some hope...
August 2016: Journal of Public Health Policy
https://www.readbyqxmd.com/read/28606185/non-malarial-infectious-diseases-of-antenatal-care-in-pregnant-women-in-franceville-gabon
#8
Irene Pegha Moukandja, Edgard Brice Ngoungou, Guy Joseph Lemamy, Ulrick Bisvigou, Antoine Gessain, Fousseyni S Toure Ndouo, Mirdad Kazanji, Jean Bernard Lekana-Douki
BACKGROUND: In sub-tropical countries, infectious diseases remain one of the main causes of mortality. Because of their lack of active immunity, pregnant women and their unborn children represent the most susceptible people. In Gabon, data on infectious diseases of pregnant women such as syphilis and rubella are either scarce or very old. Few studies have assessed T. gondii infection during pregnancy in the country. Here, we evaluate seroprevalence of HIV, HTVL-1, syphilis and T. gondii and rubella infection during antenatal care among women living in Franceville, Gabon...
June 12, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28606078/how-to-select-a-proper-early-warning-threshold-to-detect-infectious-disease-outbreaks-based-on-the-china-infectious-disease-automated-alert-and-response-system-cidars
#9
Ruiping Wang, Yonggen Jiang, Engelgau Michael, Genming Zhao
BACKGROUND: China Centre for Diseases Control and Prevention (CDC) developed the China Infectious Disease Automated Alert and Response System (CIDARS) in 2005. The CIDARS was used to strengthen infectious disease surveillance and aid in the early warning of outbreak. The CIDARS has been integrated into the routine outbreak monitoring efforts of the CDC at all levels in China. Early warning threshold is crucial for outbreak detection in the CIDARS, but CDCs at all level are currently using thresholds recommended by the China CDC, and these recommended thresholds have recognized limitations...
June 12, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28604255/the-effectiveness-of-measles-mumps-rubella-mmr-vaccination-in-the-prevention-of-pediatric-hospitalizations-for-targeted-and-untargeted-infections-a-retrospective-cohort-study
#10
Giuseppe La Torre, Rosella Saulle, Brigid Unim, Angela Meggiolaro, Angelo Barbato, Alice Mannocci, Antonietta Spadea
OBJECTIVES: To evaluate the effectiveness of the measles-mumps-rubella (MMR) vaccine in reducing hospitalizations for infectious disease, targeted and not targeted, as well as from respiratory diseases in children in Rome. METHODS: The cohort was recomposed through record linkage of 2 archives (vaccination register and hospital discharge records. RESULTS: The analysis included 11,004 children. 20.9% did not receive the MMR vaccination, 49% and 30...
June 12, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28604161/history-repeats-itself-in-japan-failure-to-learn-from-rubella-epidemic-leads-to-failure-to-provide-the-hpv-vaccine
#11
Yusuke Tanaka, Yutaka Ueda, Kiyoshi Yoshino, Tadashi Kimura
Eradication of vaccine-preventable diseases is one of the most important goals of public health interventions. Herd immunity can be established by national vaccination programs. However, once the national vaccination program stops for any reason, unprotected group will be generated depending on an unfortunate year of birth. Currently, there are 2 major concerns regarding vaccine cohort gaps in Japan: one is for the rubella vaccine, the other for the human papillomavirus (HPV) vaccine.
June 12, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28604142/rubella-antibodies-in-australian-immunoglobulin-products
#12
Megan K Young, Joseph Bertolini, Pushpa Kotharu, Darryl Maher, Allan W Cripps
Rubella antibodies are not routinely measured in immunoglobulin products and there is a lack of information on the titer in Australian products. To facilitate future studies of the effectiveness of passive immunisation for preventing rubella and congenital rubella syndrome, this study measured the concentration of rubella-specific antibodies in Australian intramuscular (IM) and intravenous (IV) human immunoglobulin products suitable for post-exposure prophylaxis using a chemiluminescent immunoassay. The GMT ± GSD for the IM product was 19 ± 1...
June 12, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28602605/vaccination-in-newly-arrived-immigrants-to-the-european-union
#13
Roman Prymula, Jana Shaw, Roman Chlibek, Ingrid Urbancikova, Karolina Prymulova
The challenge of assimilating millions of immigrants in the European region each year presents significant socioeconomic issues. Among them is the threat of vaccine preventable diseases (VPDs) disease transmission within immigrant groups and the broader population given the permeability of nation state borders. A total of 3.8 million people immigrated to the European Union (EU) in 2014, among those were 1.6 million non-EU nationals. While vaccines have markedly reduced the transmission of disease, clusters of under-vaccinated individuals potentiate the rapid transmission of once-eradicated or controlled diseases...
June 8, 2017: Vaccine
https://www.readbyqxmd.com/read/28601859/media-and-measles-rubella-vaccination-campaign-musings-from-pondicherry
#14
Adhisivam Bethou, Venkatesh Chandrasekaran
No abstract text is available yet for this article.
May 15, 2017: Indian Pediatrics
https://www.readbyqxmd.com/read/28595358/reduced-antibody-response-to-infant-measles-vaccination-effects-based-on-type-and-timing-of-the-first-vaccine-dose-persist-after-the-second-dose
#15
Sara Carazo Perez, Gaston De Serres, Alexandre Bureau, Danuta M Skowronski
Background: The effect of age at first dose on the immunogenicity of a two-dose pediatric schedule of Measles-Mumps-Rubella (MMR) or MMR-Varicella (MMRV) vaccines was assessed in children born to mostly vaccinated mothers. Methods: Immunogenicity data among children given their first measles vaccine dose between 11 and 22 months of age were pooled from five randomized controlled trials conducted in Europe and the United States between 2004 and 2010. Measles antibody titers were measured by ELISA before/after each dose: geometric mean concentrations (GMCs) and the proportion sero-negative (GMC<150mIU/ml) were derived by age at first dose...
June 8, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28594599/genetic-variants-in-the-il-4-il-13-pathway-influence-measles-vaccine-responses-and-vaccine-failure-in-children-from-mozambique
#16
Holly D Clifford, Catherine M Hayden, Siew-Kim Khoo, Denise Naniche, Inacio M Mandomando, Guicheng Zhang, Peter Richmond, Peter N Le Souëf
Despite effective measles vaccines, measles still causes severe morbidity and mortality worldwide, particularly in developing countries. The Th2 pathway involving interleukin (IL)-4 and IL-13 cytokines, and their receptor IL-4Rα, play important roles in the Th1/Th2 balance and antibody production. A Th2 skewing of the cytokine milieu may affect vaccine responses. We investigated IL-4, IL-13, and IL-4Rα polymorphisms and their impact on measles IgG responses and measles vaccine failure, in two separate cohorts: 12-month-old Australian children immunized with measles-mumps-rubella vaccine (n = 137) and a case/control cohort of children aged 6 months-14 years from Mozambique, Africa (n = 89), some of whom were vaccinated, but still contracted measles (vaccine failure)...
June 8, 2017: Viral Immunology
https://www.readbyqxmd.com/read/28591403/preliminary-multiplex-microarray-igg-immunoassay-for-the-diagnosis-of-toxoplasmosis-and-rubella
#17
Priscila T Baschirotto, Marco A Krieger, Leonardo Foti
BACKGROUND: During pregnancy, toxoplasmosis and rubella can cause serious damage to the mother and the foetus through vertical transmission. Early diagnosis enables implementation of health measures aimed at preventing vertical transmission and minimising damage caused by these diseases. OBJECTIVE: Here, we report the development of a multiplex assay for simultaneous detection of IgG antibodies produced during toxoplasmosis and rubella infection. METHODS: This assay is based on xMap technology...
June 2017: Memórias do Instituto Oswaldo Cruz
https://www.readbyqxmd.com/read/28585603/etiological-and-epidemiological-factors-in-hearing-impaired-students-in-van-east-of-turkey-a-case-series
#18
Ahmet Faruk Kiroglu, Muzaffer Ari, Nazim Bozan, Mehmet Parlak, Hakan Cankaya
The aim of the present case series was to investigate the causes of hearing loss in the children studying at a primary School for the deaf in Van Province, Turkey. The present series included 95 children with sensorineural hearing loss. Otoscopic and ophthalmological examinations, pure-tone audiometry, and tympanometry were performed for each patient. Measles IgG, rubella IgG, cytomegalovirus (CMV) IgG, toxoplasma IgG, herpes simplex virus (HSV) Type I (HSV-I) IgG, HSV Type II (HSV-II) IgG, and Mycoplasma pneumonia IgG were evaluated in serum samples...
June 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28584277/analysis-of-aquaporins-in-brassicaceae-species-reveals-high-level-of-conservation-and-dynamic-role-against-biotic-and-abiotic-stress-in-canola
#19
Humira Sonah, Rupesh K Deshmukh, Caroline Labbé, Richard R Bélanger
Aquaporins (AQPs) are of vital importance in the cellular transport system of all living organisms. In this study, genome-wide identification, distribution, and characterization of AQPs were determined in Arabidopsis lyrata, Capsella grandiflora, C. rubella, Eutrema salsugineum, Brassica rapa, B. oleracea, and B. napus (canola). Classification and phylogeny of AQPs revealed the loss of XIPs and NIP-IIIs in all species. Characterization of distinctive AQP features showed a high level of conservation in spacing between NPA-domains, and selectivity filters...
June 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28583150/prevalence-of-pregnancy-relevant-infections-in-a-rural-setting-of-ghana
#20
Fabian Völker, Paul Cooper, Oliver Bader, Angela Uy, Ortrud Zimmermann, Raimond Lugert, Uwe Groß
BACKGROUND: Although infectious diseases still account for a high burden of morbidity and mortality in sub-Saharan Africa, simultaneous investigations on multiple infections affecting maternal and child health are missing. METHODS: We conducted a cross-sectional, single-centre pilot study in a rural area of Ghana to assess the infectiological profile during pregnancy. Screening of 180 expectant mothers was done by vaginal swabs and serology to detect the most common pregnancy-relevant infections...
June 6, 2017: BMC Pregnancy and Childbirth
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