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https://www.readbyqxmd.com/read/27905834/rubella-outbreak-and-outbreak-management-in-a-school-setting-china-2014
#1
Caiyun Chang, Huilai Ma, Wenjia Liang, Pei Hu, Xianghuan Mo, Zhijie An, Huizhen Zheng
BACKGROUND: An active response to a rubella outbreak may interrupt disease transmission, and outbreak response immunization (ORI) can increase immunity among persons who might otherwise not be protected. On March 17, 2014, a rubella outbreak was reported in a middle school in Guangzhou city, China. We conducted an investigation to assess impact of a policy of exclusion of cases from school and of ORI. METHODS: Active surveillance was used to find cases of rubella...
December 1, 2016: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/27905647/-cleft-lip-palate-and-flour-fortification-with-folic-acid-in-chile
#2
Angélica Paulos, Paulina Pino, Gabriel Cavada, Carolina Lagos, Valentina Broussain, Andrea Hasbún
BACKGROUND: The effect of food fortification with folic acid on the incidence of lip-palate fissures (FLP) is under discussion. AIM: To calculate the rate of hospital discharges due to cleft lip and palate (CLP) and explore whether they decreased after the start of folic acid fortification in Chile. MATERIAL AND METHODS: The hospital discharge databases published by the Chilean Ministry of Health were analyzed. The trends of discharge rates due to CLP of children of less than one year of life (ICD-10 Q350-379 code) and live births (lb) were calculated from 1986 to 2012...
August 2016: Revista Médica de Chile
https://www.readbyqxmd.com/read/27899091/vaccination-in-secondary-school-students-expedites-rubella-control-and-prevents-congenital-rubella-syndrome
#3
Hanqing He, Rui Yan, Xuewen Tang, Yang Zhou, Xuan Deng, Shuyun Xie
BACKGROUND: In order to control the spread of rubella and reduce the risk for congenital rubella syndrome, an additional rubella vaccination program was set up for all secondary school students since 2008 in Zhejiang, China. METHODS: We conducted a descriptive analysis of rubella incidence among different age groups from 2005 to 2015 and a serosurvey of female subjects aged 15-39 years to understand the possible effects of this immunization program. RESULTS: The average annual rubella incidence rate had decreased from 15...
November 30, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27896875/disseminated-cobblestone-like-skin-lumps-in-a-newborn
#4
Z X Ren, H Q Jiang, L X Zhang, Q D Deng, J Y Zhang, X P Mu, J Yang
An newborn boy showed multiple skin lumps at birth. On examination, there were disseminated red cobblestone-like skin neoplasms, 5-30mm in diameter with hard serosanguineous crust, some were with scabs, over the scalp, face, trunk and extremities (Fig. 1A,B). The liver was 3 cm palpable below the costal margin. He was active and stable. The mother' prenatal investigation on antibodies of rubella, herpes simplex virus (HSV) and hepatitis B surface antigen were positive. The baby's antibodies for HAV, HBV, HCV, rubella, HSV, HIV and syphilis were negative...
November 29, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27896559/antiviral-activity-of-hemolymph-of-podalia-against-rubella-virus
#5
N D Carvalho, R Z Mendonça, M I Oliveira, S P Curti, T F Barbosa, P E Silva, N N Taniwaki, M Tonelotto, D N S Giovanni, R H P Moraes, C A Figueiredo
Many active principles produced by animals, plants and microorganisms have been employed in the development of new drugs for the treatment of human diseases. Among animals known to produce pharmacologically active molecules that interfere in human cell physiology. Rubella virus (genus Rubivirus, family Togaviridae) is a single stranded RNA virus of positive genome polarity. Rubella virus infection of susceptible women during the first trimester of pregnancy often results in long-term virus persistence in the fetus causing multiple organ abnormalities...
November 28, 2016: Cytotechnology
https://www.readbyqxmd.com/read/27895276/rubella-immunity-in-pregnant-native-taiwanese-and-immigrants-from-asian-countries
#6
Yeong-Hwa Zen, Ching-Tang Shih, Wan-Ju Kung, Chien-Hung Lee, Ching-Chiang Lin
Vaccination is considered the most effective method to prevent rubella spread and congenital rubella syndrome (CRS). The aim of the present study was to investigate the rubella immunity among native and immigrant pregnant women in Taiwan. From 2000 to 2014, a total of 16,879 pregnant women who received routine prenatal examinations were recruited in this study. The rubella IgG antibodies were assayed using a microparticle enzyme immunoassay or chemiluminescent microparticle immunoassay. Subjects were categorized by nationality and subcategorized by specific periods of time for comparison...
November 28, 2016: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/27893360/vaccine-preventable-diseases-in-pediatric-patients-a-review-of-measles-mumps-rubella-and-varicella
#7
Deborah A Levine
Vaccine-preventable diseases such as measles, mumps, rubella, and varicella continue to plague children and adults worldwide. Although public health programs have helped decrease the prevalence and sequelae of these diseases, outbreaks still occur. To limit the spread of these diseases, emergency clinicians must be able to readily identify the characteristic presentations of the rashes associated with measles, rubella, and varicella, as well as the common presenting features associated with mumps. Diagnostic laboratory studies are not usually necessary, as a complete history and physical examination usually lead to an accurate diagnosis...
December 2016: Pediatric Emergency Medicine Practice
https://www.readbyqxmd.com/read/27887796/vaccine-strategies-optimising-outcomes
#8
Karin Hardt, Paolo Bonanni, Susan King, Jose Ignacio Santos, Mostafa El-Hodhod, Gregory D Zimet, Scott Preiss
Successful immunisation programmes generally result from high vaccine effectiveness and adequate uptake of vaccines. In the development of new vaccination strategies, the structure and strength of the local healthcare system is a key consideration. In high income countries, existing infrastructures are usually used, while in less developed countries, the capacity for introducing new vaccines may need to be strengthened, particularly for vaccines administered beyond early childhood, such as the measles or human papillomavirus (HPV) vaccine...
November 22, 2016: Vaccine
https://www.readbyqxmd.com/read/27884915/a-case-of-congenital-rubella-syndrome-and-infection-in-south-east-london-in-2015-prevention-diagnosis-and-the-public-health-response
#9
Elizabeth Marchant, Louise Bishop, Debbie Flaxman, Jenni Jagodzinski, Mahesh Nanjundappa, Prasanna Muniyappa, Rebecca Cordery
No abstract text is available yet for this article.
December 2016: British Journal of General Practice: the Journal of the Royal College of General Practitioners
https://www.readbyqxmd.com/read/27879555/safety-and-immunogenicity-of-dtap5-ipv-compared-with-dtap5-plus-ipv-as-the-fifth-dose-in-children-4-to-6-years-of-age
#10
Michael J Smith, Emilia Jordanov, Xiaohua Sheng, Peter H Tsang
BACKGROUND: Immunogenicity and safety of stand-alone diphtheria, tetanus toxoid, 5-component acellular pertussis vaccine adsorbed, inactivated poliovirus (IPV) combination vaccine (DTaP5-IPV) was compared with separate DTaP5 plus IPV vaccines as fifth dose in children 4-6 years of age. METHODS: In this phase III, controlled, multicenter, randomized, open-label study participants were randomized to DTaP5-IPV plus measles/mumps/rubella (MMR) and varicella virus (VZV) vaccines (Group 1; N=324), DTaP5+IPV with MMR and VZV (Group 2; N=327), DTaP5-IPV with/without MMR/VZV (Group 3; N=2419), or DTaP5+IPV with/without MMR/VZV (Group 4; N=302)...
November 22, 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27879554/measles-and-rubella-seroprevalence-among-hiv-infected-and-uninfected-zambian-youth
#11
Catherine G Sutcliffe, Kelly Searle, Hellen K Matakala, Dip Biomed, Michelle Greenman, Kaitlin Rainwater-Lovett, Philip E Thuma, William J Moss
BACKGROUND: Measles and congenital rubella syndrome remain significant causes of morbidity and mortality despite available vaccines. HIV-infected youth may be at increased risk of measles because of greater waning immunity following vaccination. At a population level, they constitute a potentially large pool of susceptibles to measles and rubella. More data among HIV-infected youth in sub-Saharan Africa are needed to guide vaccination policy and control strategies. METHODS: This cross-sectional study was nested within two ongoing studies of malaria and HIV in Zambia...
November 22, 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27873563/comparative-dynamics-seasonality-in-transmission-and-predictability-of-childhood-infections-in-mexico
#12
A S Mahmud, C J E Metcalf, B T Grenfell
The seasonality and periodicity of infections, and the mechanisms underlying observed dynamics, can have implications for control efforts. This is particularly true for acute childhood infections. Among these, the dynamics of measles is the best understood and has been extensively studied, most notably in the UK prior to the start of vaccination. Less is known about the dynamics of other childhood diseases, particularly outside Europe and the United States. In this paper, we leverage a unique dataset to examine the epidemiology of six childhood infections - measles, mumps, rubella, varicella, scarlet fever and pertussis - across 32 states in Mexico from 1985 to 2007...
November 22, 2016: Epidemiology and Infection
https://www.readbyqxmd.com/read/27872364/zika-virus-the-new-rubella-epidemic
#13
Kerrie K Nguyen, Brigid E O'Brien, Russell W Steele
No abstract text is available yet for this article.
November 20, 2016: Clinical Pediatrics
https://www.readbyqxmd.com/read/27869981/description-of-the-first-cases-of-zika-virus-fever-investigated-in-municipalities-of-the-brazilian-northeastern-region-2015
#14
Francieli Fontana Sutile Tardetti Fantinato, Emerson Luiz Lima Araújo, Igor Gonçalves Ribeiro, Marcia Regina de Andrade, Anna Livia de Medeiros Dantas, Jakeline Maria Trinta Rios, Odila Márcia Vinhas da Silva, Maria do Socorro da Silva, Renata Valeria Nóbrega, Daniel de Araújo Batista, Priscila Leal E Leite, Eduardo Saad, Jadher Percio, Elionardo Andrade Resende, Priscila Bochi de Souza, Marcelo Yoshito Wada
OBJECTIVE: to confirm Zika virus circulation and discard other etiological agents in an outbreak occurred in the states of Rio Grande do Norte, Maranhão and Paraíba, in May, 2015. METHODS: this is a case series descriptive study with residents in Natal-RN, Barra do Corda-MA, São Luis-MA and João Pessoa-PB, with 20 cases in each state, presenting rash, absent or mild fever and one of the following signs/symptoms: conjunctival hyperemia, arthralgia or limb edema; RT-PCR/isolation tests for Zika, enterovirus and respiratory viruses, and serology tests (dengue, rubella and parvovirus B19) were performed...
October 2016: Epidemiologia e Servicos de Saude: Revista do Sistema Unico de Saude do Brasil
https://www.readbyqxmd.com/read/27869413/humoral-immunity-to-tetanus-measles-and-rubella-in-children-with-acute-lymphoblastic-leukemia-after-chemotherapy
#15
Myriam Onorateli, Claudia Botana, Laura Peralta, Magali Rebollo, Silvina Ruvinsky, Myriam Guitter, Maria S Felice, Mercedes Posadas, Silvina Evangelista, Maria V Villar, Mariana Golluscio, Agustina Molina, Lidia Fraquelli
Chemotherapy regimens and clinical support advances have improved survival in children with acute lymphoblastic leukemia. The after-effects of treatment are a reason for concern, including damage to the immune system induced by immunosuppressive therapy which is reflected in the loss of antibody protection provided by prior immunizations. Our goal was to assess the presence of measles, rubella, and tetanus protective antibody titers among patients with acute lymphoblastic leukemia after completing chemotherapy...
December 1, 2016: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/27866768/estimating-the-burden-of-rubella-virus-infection-and-congenital-rubella-syndrome-through-a-rubella-immunity-assessment-among-pregnant-women-in-the-democratic-republic-of-the-congo-potential-impact-on-vaccination-policy
#16
Mary M Alleman, Kathleen A Wannemuehler, Lijuan Hao, Ludmila Perelygina, Joseph P Icenogle, Emilia Vynnycky, Franck Fwamba, Samuel Edidi, Audry Mulumba, Kassim Sidibe, Susan E Reef
BACKGROUND: Rubella-containing vaccines (RCV) are not yet part of the Democratic Republic of the Congo's (DRC) vaccination program; however RCV introduction is planned before 2020. Because documentation of DRC's historical burden of rubella virus infection and congenital rubella syndrome (CRS) has been minimal, estimates of the burden of rubella virus infection and of CRS would help inform the country's strategy for RCV introduction. METHODS: A rubella antibody seroprevalence assessment was conducted using serum collected during 2008-2009 from 1605 pregnant women aged 15-46years attending 7 antenatal care sites in 3 of DRC's provinces...
December 12, 2016: Vaccine
https://www.readbyqxmd.com/read/27863513/epidemiology-of-rubella-virus-cases-in-the-pre-vaccination-era-of-ethiopia-2009-2015
#17
Mekonen Getahun, Berhane Beyene, Kathleen Gallagher, Ayesheshem Ademe, Birke Teshome, Mesfin Tefera, Anjelo Asha, Aklog Afework, Esete Assefa, Yoseph HaileMariam, Yonas HaileGiorgis, Hiwot Ketema, Dejenie Shiferaw, Ayenachew Bekele, Daddi Jima, Amha Kebede
BACKGROUND: Rubella is a common mild rash illness caused by rubella virus. The majority of infections occur in children and young adults. The infection is the cause of a serious birth defect known as Congenital Rubella Syndrome (CRS) when a woman acquires infection early in pregnancy. Ethiopia has not yet established rubella virus surveillance and has not yet introduced rubella vaccine into the routine immunization program. We characterize the epidemiology of laboratory confirmed rubella virus cases collected through measles surveillance from 2009 to 2015 to better understand the burden of the disease in the country...
November 18, 2016: BMC Public Health
https://www.readbyqxmd.com/read/27862309/study-of-greek-children-and-youths-with-cystic-fibrosis-identifies-immunisation-gaps-and-delays
#18
Helena C Maltezou, Stavros Doudounakis, Maria Lekaditi, Kalliopi Tanou, Panos Katerelos, Maria Theodoridou
AIM: Data about immunisation rates in cystic fibrosis (CF) patients are scarce. We estimated the rates and timeliness of immunisations in CF patients aged 0.55-22 years. METHODS: We studied 122 subjects at a hospital in Greece in 2014. A standard questionnaire was used to collect data and parents' opinions about immunisations. RESULTS: The complete immunisation rates were 92.6% for diphtheria-tetanus-acellular pertussis-inactivated poliomyelitis-Haemophilus influenzae (DTaP-IPV-Hib), 96...
November 10, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27855146/global-routine-vaccination-coverage-2015
#19
Rebecca M Casey, Laure Dumolard, M Carolina Danovaro-Holliday, Marta Gacic-Dobo, Mamadou S Diallo, Lee M Hampton, Aaron S Wallace
In 1974, the World Health Organization (WHO) established the Expanded Program on Immunization* to provide protection against six vaccine-preventable diseases through routine infant immunization (1). Based on 2015 WHO and United Nations Children's Fund (UNICEF) estimates, global coverage with the third dose of diphtheria-tetanus-pertussis vaccine (DTP3), the first dose of measles-containing vaccine (MCV1) and the third dose of polio vaccine (Pol3) has remained stable (84%-86%) since 2010. From 2014 to 2015, estimated global coverage with the second MCV dose (MCV2) increased from 39% to 43% by the end of the second year of life and from 58% to 61% when older age groups were included...
November 18, 2016: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/27854416/rubella-in-poland-in-2014
#20
Iwona Paradowska-Stankiewicz, Justyna Rogalska, Aleksandra Polkowska
BACKGROUND: In 2004, Poland has adopted the WHO goal of rubella elimination and congenital rubella syndrome prevention. The main target of the Programme is to stop transmission of the virus in the environment and prevention of congenital rubella in children. In Poland participation in the rubella elimination program requires clinical diagnosis of rubella cases and their confirmation with laboratory tests. Vaccination against rubella was introduced in 1987, initially only in 13 - year-old girls...
2016: Przegla̧d Epidemiologiczny
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