keyword
MENU ▼
Read by QxMD icon Read
search

Bacterial persistence

keyword
https://www.readbyqxmd.com/read/29681892/bacterial-communities-of-diatoms-display-strong-conservation-across-strains-and-time
#1
Gregory Behringer, Michael A Ochsenkühn, Cong Fei, Jhamal Fanning, Julie A Koester, Shady A Amin
Interactions between phytoplankton and bacteria play important roles in shaping the microenvironment surrounding these organisms and in turn influence global biogeochemical cycles. This microenvironment, known as the phycosphere, is presumed to shape the bacterial diversity around phytoplankton and thus stimulate a diverse array of interactions between both groups. Although many studies have attempted to characterize bacterial communities that associate and interact with phytoplankton, bias in bacterial cultivation and consistency and persistence of bacterial communities across phytoplankton isolates likely impede the understanding of these microbial associations...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29680350/novel-pet-and-near-infrared-imaging-probes-for-the-specific-detection-of-bacterial-infections-associated-with-cardiac-devices
#2
Kiyoko Takemiya, Xinghai Ning, Wonewoo Seo, Xiaojian Wang, Rafi Mohammad, Giji Joseph, Jane S Titterington, Colleen S Kraft, Jonathan A Nye, Niren Murthy, Mark M Goodman, W Robert Taylor
OBJECTIVES: The aim of this study was to develop imaging agents to detect early stage infections in implantable cardiac devices. BACKGROUND: Bacteria ingest maltodextrins through the specific maltodextrin transporter. We developed probes conjugated with either a fluorescent dye (maltohexaose fluorescent dye probe [MDP]) or a F-18 (F18 fluoromaltohexaose) and determined their usefulness in a model of infections associated with implanted cardiac devices. METHODS: Stainless steel mock-ups of medical devices were implanted subcutaneously in rats...
April 13, 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29679779/biomimetic-3d-in-vitro-model-of-biofilm-triggered-osteomyelitis-for-investigating-hematopoiesis-during-bone-marrow-infections
#3
Annamarija Raic, Sophie Riedel, Elena Kemmling, Karen Bieback, Joerg Overhage, Cornelia Lee-Thedieck
In this work, we define the requirements for a human-based osteomyelitis model which overcomes the limitations of state of the art animal models. Osteomyelitis is a severe and difficult to treat infection of the bone that develops rapidly, making it difficult to study in humans. We have developed a 3D in vitro model of the bone marrow, comprising a macroporous material, human hematopoietic stem and progenitor cells (HSPCs) and mesenchymal stromal cells (MSCs). Inclusion of biofilms grown on an implant into the model system allowed us to study the effects of postoperative osteomyelitis-inducing bacteria on the bone marrow...
April 18, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29678921/a-repeating-sulfated-galactan-motif-resuscitates-dormant-micrococcus-luteus
#4
Thomas Böttcher, Dávid Szamosvári, Jon Clardy
Only a small fraction of bacteria can autonomously initiate growth on agar plates. Non-growing bacteria typically enter a metabolically inactive dormant state and require specific chemical trigger factors or signals to exit this state and resume growth. Micrococcus luteus has become a model organism for this important yet poorly understood phenomenon. So far, only few resuscitation signals have been described and all of them are produced endogenously by bacterial species. We report the discovery of a novel type of resuscitation signal that allows M...
April 20, 2018: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29678647/post-mortem-retrieval-of-arterial-allografts-preliminary-results
#5
Dorian Verscheure, Julien Gaudric, Jérémie Jayet, Philippe Tresson, Mohamed Jarraya, Pierre Julia, Marc Coggia, Laurent Chiche, Fabien Koskas
OBJECTIVES: Cryopreserved arterial allografts are vascular substitutes used for arterial reconstructions in a septic field. Their use remains however limited by the shortage of donors. One of the possibilities to address this lack of grafts is to multiply the sources of retrieval. The objective of this preliminary study was the evaluation of the early clinical results and the microbiological safety of arterial grafts retrieved after death. MATERIAL AND METHODS: In addition to the standard conditions of arterial sampling the criteria of inclusion for postmortem retrieval comprised the refrigeration of the body of the donor within four hours following the death, a 24-hour time limit from the death, and the availability of an adapted place for retrieval (surgical unit or death chamber respecting the required aseptic conditions)...
April 17, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29675476/peritoneal-tuberculosis-after-robot-assisted-laparoscopic-prostatectomy-with-extended-lymph-node-dissection
#6
Suruga Saito, Katsuhiro Ito, Keiyu Matsumoto, Motofumi Tajima, Takayuki Goto, Haruki Ito, Yumi Manabe, Mutsuki Mishina, Hiroshi Okuno
Background: Peritoneal tuberculosis (TB) is a relatively uncommon presentation of extrapulmonary TB. Early diagnosis of peritoneal TB is difficult because of its nonspecific clinical manifestation such as abdominal pain, fever, or ascites. Especially early after surgery of abdomen or pelvis, these symptoms can be misdiagnosed as septic peritonitis. There are few reports of peritoneal TB as a postoperative complication of laparoscopic surgery. Here, we describe a first case of peritoneal TB after robot-assisted laparoscopic prostatectomy (RALP) with extended lymph node dissection...
2018: Journal of Endourology Case Reports
https://www.readbyqxmd.com/read/29675003/role-of-micrornas-and-exosomes-in-helicobacter-pylori-and-epstein-barr-virus-associated-gastric-cancers
#7
REVIEW
Iva Polakovicova, Sofia Jerez, Ignacio A Wichmann, Alejandra Sandoval-Bórquez, Nicolás Carrasco-Véliz, Alejandro H Corvalán
Emerging evidence suggests that chronic inflammation caused by pathogen infection is connected to the development of various types of cancer. It is estimated that up to 20% of all cancer deaths is linked to infections and inflammation. In gastric cancer, such triggers can be infection of the gastric epithelium by either Helicobacter pylori ( H. pylori ), a bacterium present in half of the world population; or by Epstein-Barr virus (EBV), a double-stranded DNA virus which has recently been associated with gastric cancer...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29674747/glycointeractions-in-bacterial-pathogenesis
#8
REVIEW
Jessica Poole, Christopher J Day, Mark von Itzstein, James C Paton, Michael P Jennings
Many important interactions between bacterial pathogens and their hosts are highly specific binding events that involve host or pathogen carbohydrate structures (glycans). Glycan interactions can mediate adhesion, invasion and immune evasion and can act as receptors for toxins. Several bacterial pathogens can also enzymatically alter host glycans to reveal binding targets, degrade the host cell glycans or alter the function of host glycoproteins. In recent years, high-throughput screening technologies, such as lectin, glycan and mucin microarrays, have transformed the field by identifying new bacterial-host glycointeractions, which are crucial for colonization, persistence and disease...
April 19, 2018: Nature Reviews. Microbiology
https://www.readbyqxmd.com/read/29670601/population-dynamics-of-lactobacillus-helveticus-in-swiss-gruy%C3%A3-re-type-cheese-manufactured-with-natural-whey-cultures
#9
Aline Moser, Karl Schafroth, Leo Meile, Lotti Egger, René Badertscher, Stefan Irmler
Lactobacillus helveticus , a ubiquitous bacterial species in natural whey cultures (NWCs) used for Swiss Gruyère cheese production, is considered to have crucial functions for cheese ripening such as enhancing proteolysis. We tracked the diversity and abundance of L. helveticus strains during 6 months of ripening in eight Swiss Gruyère-type cheeses using a culture-independent typing method. The study showed that the L. helveticus population present in NWCs persisted in cheese and demonstrated a stable multi-strain coexistence during cheese ripening...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29670191/fecal-microbiota-transplantation-reverses-antibiotic-and-chemotherapy-induced-gut-dysbiosis-in-mice
#10
Quentin Le Bastard, Tonya Ward, Dimitri Sidiropoulos, Benjamin M Hillmann, Chan Lan Chun, Michael J Sadowsky, Dan Knights, Emmanuel Montassier
Fecal microbiota transplantation (FMT) is now widely used to treat recurrent Clostridium difficile infection, but has been less studied as a means to restore microbiome diversity and composition following antibiotic or chemotherapy treatments. The purpose of our study was to assess the efficacy of FMT to reverse antibiotic- and chemotherapy-induced gut dysbiosis in a mouse model. C57BL/6J mice were treated with ampicillin for 1 week and/or received a single intraperitoneal injection of 5-Fluorouracil. Fresh stool was collected and analyzed using shotgun metagenomics and the Illumina sequencing platform...
April 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29668898/the-activity-of-nitrifying-microorganisms-in-a-high-altitude-andean-wetland
#11
Verónica Molina, Cristina Dorador, Camila Fernández, Laura Bristow, Yoanna Eissler, Martha Hengst, Klaudia Hernandez, Lasse Mork Olsen, Chris Harrod, Francisca Marchant, Cristobal Anguita, Marcela Cornejo
High altitude wetland holds freshwater springs, evaporitic ponds and lagoon with variable salinity and nutrients, potentially influencing the ecology of nitrifying communities. In this study, nitrifying microorganisms in Salar de Huasco (Chile) were surveyed to determine bacterial and archaeal contribution to ammonium (AO), nitrite oxidation (NO), ammonium uptake (AU) during wet and dry seasons. The activity signals from these group were assessed by specific amoA-qPCR transcription, 15N tracer studies and addition of group specific inhibitor experiments for nitrifying microorganisms (N1-guanyl-1, 7-diaminoheptane [GC7]-archaeal specific and allylthiourea [ATU]-bacterial specific)...
April 12, 2018: FEMS Microbiology Ecology
https://www.readbyqxmd.com/read/29668758/clostridium-sordellii-outer-spore-proteins-maintain-spore-structural-integrity-and-promote-bacterial-clearance-from-the-gastrointestinal-tract
#12
Rebecca Rabi, Sarah Larcombe, Rommel Mathias, Sheena McGowan, Milena Awad, Dena Lyras
Bacterial spores play an important role in disease initiation, transmission and persistence. In some species, the exosporium forms the outermost structure of the spore and provides the first point of contact between the spore and the environment. The exosporium may also be involved in spore adherence, protection and germination. Clostridium sordellii is a highly lethal, spore forming pathogen that causes soft-tissue infections, enteritis and toxic-shock syndrome. Despite the importance of C. sordellii spores in disease, spore proteins from this bacterium have not been defined or interrogated functionally...
April 18, 2018: PLoS Pathogens
https://www.readbyqxmd.com/read/29666284/biofilms-comprise-a-component-of-the-annual-cycle-of-vibrio-cholerae-in-the-bay-of-bengal-estuary
#13
Marzia Sultana, Suraia Nusrin, Nur A Hasan, Abdus Sadique, Kabir U Ahmed, Atiqul Islam, Anwar Hossain, Ira Longini, Azhar Nizam, Anwar Huq, Abul K Siddique, David A Sack, Richard B Sack, Rita R Colwell, Munirul Alam
Vibrio cholerae , an estuarine bacterium, is the causative agent of cholera, a severe diarrheal disease that demonstrates seasonal incidence in Bangladesh. In an extensive study of V. cholerae occurrence in a natural aquatic environment, water and plankton samples were collected biweekly between December 2005 and November 2006 from Mathbaria, an estuarine village of Bangladesh near the mangrove forests of the Sundarbans. Toxigenic V. cholerae exhibited two seasonal growth peaks, one in spring (March to May) and another in autumn (September to November), corresponding to the two annual seasonal outbreaks of cholera in this region...
April 17, 2018: MBio
https://www.readbyqxmd.com/read/29666276/mine-conformational-switching-confers-robustness-on-self-organized-min-protein-patterns
#14
Jonas Denk, Simon Kretschmer, Jacob Halatek, Caroline Hartl, Petra Schwille, Erwin Frey
Protein patterning is vital for many fundamental cellular processes. This raises two intriguing questions: Can such intrinsically complex processes be reduced to certain core principles and, if so, what roles do the molecular details play in individual systems? A prototypical example for protein patterning is the bacterial Min system, in which self-organized pole-to-pole oscillations of MinCDE proteins guide the cell division machinery to midcell. These oscillations are based on cycling of the ATPase MinD and its activating protein MinE between the membrane and the cytoplasm...
April 16, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29662492/rnase-h2-loss-in-murine-astrocytes-results-in-cellular-defects-reminiscent-of-nucleic-acid-mediated-autoinflammation
#15
Kareen Bartsch, Markus Damme, Tommy Regen, Lore Becker, Lillian Garrett, Sabine M Hölter, Katharina Knittler, Christopher Borowski, Ari Waisman, Markus Glatzel, Helmut Fuchs, Valerie Gailus-Durner, Martin Hrabe de Angelis, Björn Rabe
Aicardi-Goutières syndrome (AGS) is a rare early onset childhood encephalopathy caused by persistent neuroinflammation of autoimmune origin. AGS is a genetic disorder and >50% of affected individuals bear hypomorphic mutations in ribonuclease H2 (RNase H2). All available RNase H2 mouse models so far fail to mimic the prominent CNS involvement seen in AGS. To establish a mouse model recapitulating the human disease, we deleted RNase H2 specifically in the brain, the most severely affected organ in AGS. Although RNase H2ΔGFAP mice lacked the nuclease in astrocytes and a majority of neurons, no disease signs were apparent in these animals...
2018: Frontiers in Immunology
https://www.readbyqxmd.com/read/29661869/moxifloxacin-replacement-in-contemporary-tuberculosis-drug-regimens-is-ineffective-against-persistent-mycobacterium-tuberculosis-novel-insights-from-the-cornell-mouse-model
#16
Yingjun Liu, Henry Pertinez, Geraint R Davies, Stephen H Gillespie, Anthony R Coates, Yanmin Hu
Tuberculosis (TB) caused by Mycobacterium tuberculosis remains a leading killer worldwide, and disease control is hampered by ineffective control of persistent infections. Substitution of moxifloxacin for isoniazid or ethambutol in standard TB regimens reduces treatment duration and relapse rates in animal studies and four-month regimens were not non-inferior in clinical trials. Resuscitation promoting factor (RPF) dependent bacilli have recently been implicated in M. tuberculosis persistence. We aimed to investigate the therapeutic effects of moxifloxacin substitution in the standard drug regimen for eradicating colony forming count (CFU) positive and RPF-dependent persistent M...
April 16, 2018: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/29660891/soil-microbial-communities-and-glyphosate-decay-in-soils-with-different-herbicide-application-history
#17
Keren Hernández Guijarro, Virginia Aparicio, Eduardo De Gerónimo, Martín Castellote, Eva L Figuerola, José Luis Costa, Leonardo Erijman
This study evaluates the glyphosate dissipation under field conditions in three types of soil, and aims to determine the importance of the following factors in the environmental persistence of herbicide: i) soil bacterial communities, ii) soil physicochemical properties, iii) previous exposure to the herbicide. A soil without previous record of GP application (P0) and two agricultural soils, with 5 and >10years of GP exposure (A5 and A10) were subjected to the application of glyphosate at doses of 3mg·kg-1 ...
April 11, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29659932/effects-of-bacterial-dose-and-fly-sex-on-persistence-and-excretion-of-salmonella-enterica-serovar-typhimurium-from-adult-house-flies-musca-domestica-l-diptera-muscidae
#18
Dana Nayduch, Klara Zurek, Jessica L Thomson, Kathleen M Yeater
Salmonella Typhimurium (Le Minor and Popoff 1987; Enterobacteriales: Enterobacteriaceae) is a pathogen that causes gastroenteritis in humans and can be harbored by house flies. Factors influencing excretion of S. Typhimurium from infected flies have not been elucidated but are essential for assessing transmission potential. We determined the persistence and excretion of a green fluorescent protein (GFP) expressing strain of S. Typhimurium from house flies. Individual male and female flies were fed either sterile Luria-Bertani (LB) broth (controls) or cultures of "high" (~105 colony forming units [CFU]) or "low" (~104 CFU) doses of bacteria (treatments)...
April 11, 2018: Journal of Medical Entomology
https://www.readbyqxmd.com/read/29659479/oral-dysbiotic-communities-and-their-implications-in-systemic-diseases
#19
REVIEW
Preethi Sudhakara, Abishek Gupta, Anshumouli Bhardwaj, Aruni Wilson
The human body supports the growth of a wide array of microbial communities in various niches such as the oral cavity, gastro-intestinal and urogenital tracts, and on the surface of the skin. These host associated microbial communities include yet-un-cultivable bacteria and are influenced by various factors. Together, these communities of bacteria are referred to as the human microbiome. Human oral microbiome consists of both symbionts and pathobionts. Deviation from symbiosis among the bacterial community leads to “dysbiosis”, a state of community disturbance...
April 16, 2018: Dentistry journal
https://www.readbyqxmd.com/read/29657964/vive-la-persistence-engineering-human-microbiomes-in-the-21st-century
#20
Katrine L Whiteson
I imagine a future in which children grow up with healthy microbial communities. Engineering human microbiomes might actually be achievable in the near future, as we enter an era of hunting for human-adapted bacterial strains and phages. Furthermore, breath metabolites could allow us to track whether a probiotic colonizes persistently or a phage has knocked down a microbe of interest. Recent successes with probiotics, such as bifidobacteria that can break down human milk oligosaccharides, are making a future in which infants are intentionally colonized with health-promoting strains seem less unlikely...
March 2018: MSystems
keyword
keyword
15328
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"