M Kiezun, K Dobrzyn, E Zaobidna, E Rytelewska, K Kisielewska, M Gudelska, K Orzechowska, G Kopij, K Szymanska, B Kaminska, T Kaminski, N Smolinska
Reproduction in females is an energetically demanding process. We assumed that adiponectin (ADPN), known for its role in energy balance maintenance, is also engaged in the regulation of uterine steroidogenesis in the pig. We determined the impact of ADPN alone or in combination with insulin (INS) on testosterone (T), estrone (E1 ) and estradiol (E2 ) secretion by porcine endometrium and myometrium, uterine expression of CYP17A1 and CYP19A3 genes, and endometrial abundance of P450C17 and P450AROM proteins during the peri-implantation period and the oestrous cycle, using radioimmunoassay, qPCR, and Western Blot, respectively...
September 6, 2022: Animal Reproduction Science