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Kazuo Saito, Hitoshi Kihara
STUDY DESIGN: A randomized clinical trial, with patients treated either by new 2-step orthosis or by the figure-eight-type orthosis with the distal interphalangeal (DIP) joint extended. PURPOSE OF THE STUDY: To report on our new orthosis and to evaluate the treatment efficacy of using a 2-step orthosis for the treatment of a mallet finger of tendinous origin compared with a conventional orthosis. METHODS: Forty-four patients were randomized into the 2-step or conventional orthosis groups...
October 18, 2016: Journal of Hand Therapy: Official Journal of the American Society of Hand Therapists
Marie-Catherine Drigeard Desgarnier, Corinne Zinflou, Justin D Mallet, Sébastien P Gendron, Sébastien J Méthot, Patrick J Rochette
Purpose: Human chromosomes are protected at their end by a long portion of hexameric tandem repeats, the telomere. In somatic cells, telomere attrition caused by endogenous and exogenous oxidative stress as well as DNA replication can threaten genomic integrity and lead to the deterioration of tissue functions and an age-related physiological decline. The human eye is a complex organ in which cells of different ocular tissues are exposed to photo-oxidation, high mitochondrial metabolic activity, and/or replicative pressure...
October 1, 2016: Investigative Ophthalmology & Visual Science
Young Hak Roh, Beom Koo Lee, Min Ho Park, Jung Ho Noh, Hyun Sik Gong, Goo Hyun Baek
STUDY DESIGN: Prospective cohort. INTRODUCTION: Patient comprehension of their injury, its treatment, and health care provider's instructions plays an important role in health management and recovery from trauma. PURPOSE OF THE STUDY: This study investigates the effects of health literacy (the ability to obtain, process, and understand health information needed to make appropriate health decisions) on treatment outcomes and satisfaction in patients with mallet finger injuries...
October 17, 2016: Journal of Hand Therapy: Official Journal of the American Society of Hand Therapists
Hélène Gilgenkrantz, Jérôme Gouttenoire, Vincent Mallet
No abstract text is available yet for this article.
October 2016: Médecine Sciences: M/S
Didier Bessis, Michèle Bigorre, Nausicaa Malissen, Guillaume Captier, Christine Chiaverini, Claire Abasq, Sébastien Barbarot, Olivia Boccara, Emmanuelle Bourrat, Hassan El Fertit, Catherine Eschard, Thomas Hubiche, Jean-Philippe Lacour, Nicolas Leboucq, Emmanuel Mahé, Stéphanie Mallet, Myriam Marque, Ludovic Martin, Juliette Mazereeuw-Hautier, Nathalie Milla, Alice Phan, Patrice Plantin, Marie-Christine Picot, Eve Puzenat, Valérie Rigau, Pierre Vabres, Sylvie Fraitag, Franck Boralevi
BACKGROUND: Hair collar sign (HCS) and hair tuft of the scalp (HTS) are cutaneous signs of an underlying neuroectodermal defect, but most available data are based on case reports. OBJECTIVE: We sought to define the clinical spectrum of HCS and HTS, clarify the risk for underlying neurovascular anomalies, and provide imaging recommendations. METHODS: A 10-year multicenter retrospective and prospective analysis of clinical, radiologic, and histopathologic features of HCS and HTS in pediatric patients was performed...
October 11, 2016: Journal of the American Academy of Dermatology
Mohamed Mansour Elzohairy, Adel Mohamed Salama
INTRODUCTION: The purpose of this study was to evaluate shoulder function following minimally invasive subtotal subscapularis muscle and periarticular capsuloligamentous arthroscopic release in children with Erb's palsy. METHODS: A prospective study was conducted on 15 consecutive children who underwent subtotal subscapularis muscle and periarticular capsuloligamentous arthroscopic release to treat internal rotation contracture of the shoulder joint after Erb's palsy...
October 12, 2016: Journal of Children's Orthopaedics
Nicolas Chazot, Keith R Willmott, Fabien L Condamine, Donna Lisa de-Silva, André V L Freitas, Gerardo Lamas, Hélène Morlon, Carlos E Giraldo, Chris D Jiggins, Mathieu Joron, James Mallet, Sandra Uribe, Marianne Elias
Understanding why species richness peaks along the Andes is a fundamental question in the study of Neotropical biodiversity. Several biogeographic and diversification scenarios have been proposed in the literature, but there is confusion about the processes underlying each scenario, and assessing their relative contribution is not straightforward. Here, we propose to refine these scenarios into a framework which evaluates four evolutionary mechanisms: higher speciation rate in the Andes, lower extinction rates in the Andes, older colonization times and higher colonization rates of the Andes from adjacent areas...
October 8, 2016: Molecular Ecology
M Morgiève, K N'Diaye, S Fernandez-Vidal, A-H Clair, L Mallet
INTRODUCTION: Obsessive compulsive disorder (OCD) is one of the most disabling mental health disorders due to its negative impact on the patient's quality of life as well on that of her living caregivers. This disorder generates an additional burden for relatives, which may in turn affect the family dynamics and impair the evolution of the disease. Along with medications, cognitive behavioral therapy (CBT) represents a well-validated first line of treatment for OCD. However, therapeutic responses across patients are uneven with often residual symptoms and limited quality of life improvements...
October 4, 2016: L'Encéphale
Lucie Molet, Matthieu Revest, Maxime Fournet, Erwan Donal, Martine Bonnaure-Mallet, Jacques Minet, Hervé Le Bars
Infectious endocarditis due to Cardiobacterium hominis is an uncommon event, accounting for less than 2% of all cases of infectious endocarditis. The infection of the tricuspid valve as it is reported here is extremely rare. We report the case of a tricuspid endocarditis due to Cardiobacterium hominis in a 56 year-old man who was admitted to hospital with pelvic and scapular pain. The diagnosis was established through positive blood cultures and echographic detection of a large tricuspid vegetation. Despite efficient antibiotic therapy, valve replacement was required...
October 6, 2016: Annales de Biologie Clinique
A Moradi, Y Braun, K Oflazoglu, T Meijs, D Ring, N Chen
: Radiographs and medical record of all adult patients with a mallet fracture in three hospitals between 2004 and 2014 were reviewed. International Classification of Diseases, Ninth Revision (ICD-9) codes and text search in radiographic reports were used to identify all acute patients with potential mallet fractures in our institutional database. Manually checking, 392 true mallet fractures were identified among them, 78 had subluxation at the time of diagnosis and 19 had subluxation at a later time point during treatment...
October 3, 2016: Journal of Hand Surgery, European Volume
Fanny Larsonneur, Fernando A Martin, Adeline Mallet, Marta Martinez-Gil, Vincent Semetey, Jean-Marc Ghigo, Christophe Beloin
Initial adhesion of bacterial cells to surfaces or host tissues is a key step in colonisation and biofilm formation processes, and is mediated by cell surface appendages. We previously demonstrated that Escherichia coli K-12 possesses an arsenal of silenced chaperone-usher fimbriae that are functional when constitutively expressed. Among them, production of prevalent Yad fimbriae induces adhesion to abiotic surfaces. We undertook functional characterisation of Yad fimbriae, and identified YadN as the most abundant and potential major pilin, and YadC as the potential tip-protein of Yad fimbriae...
October 3, 2016: Environmental Microbiology
Nadjib Hammoudi, Florent Laveau, Gérard Helft, Nathalie Cozic, Olivier Barthelemy, Alexandre Ceccaldi, Thibaut Petroni, Emmanuel Berman, Michel Komajda, Pierre-Louis Michel, Alain Mallet, Claude Le Feuvre, Richard Isnard
BACKGROUND: Increased left ventricular end-diastolic pressure (LVEDP) with exercise is an early sign of heart failure with preserved left ventricular ejection fraction (LVEF). The abnormal exercise increase in LVEDP is nonlinear, with most change occurring at low-level exercise. Data on non-invasive approach of this condition are scarce. Our objective was assessing E/e' to estimate low level exercise LVEDP using a direct invasive measurement as the reference method. METHODS AND RESULTS: Sixty patients with LVEF >50 % prospectively underwent both exercise cardiac catheterization and echocardiography...
September 30, 2016: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
Alaa Sweidan, Marylene Chollet-Krugler, Pierre van de Weghe, Ali Chokr, Sophie Tomasi, Martine Bonnaure-Mallet, Latifa Bousarghin
Novel butyrolactone analogues were designed and synthesized based on the known lichen antibacterial compounds, lichesterinic acids (B-10 and B-11), by substituting different functional groups on the butyrolactone ring trying to enhance its activity. All synthesized butyrolactone analogues were evaluated for their in vitro antibacterial activity against Streptococcus gordonii. Among the derivatives, B-12 and B-13 had the lowest MIC of 9.38μg/mL where they have shown to be stronger bactericidals, by 2-3 times, than the reference antibiotic, doxycycline...
September 17, 2016: Bioorganic & Medicinal Chemistry
Mark Plavsic, Klaudia Shick, Katherine F Bergmann, Laurent Mallet
Vesivirus 2117 (VV-2117) has been recently described as a contaminant of cell culture operations in several biologics manufacturing facilities. VV-2117 has been poorly studied and little information exists about its biology, pathogenicity and infectivity range in cell culture settings. In this study we evaluated the potential in vitro viral infectivity of VV-2117 using a range of established mammalian cell lines from various species, the effectiveness of virus amplification in CHO-K1 cells at differing infection levels, and the relative sensitivity of two test methods (cytopathic effect [CPE] and polymerase chain reaction [PCR]) to detect infection and viral amplification...
September 14, 2016: Biologicals: Journal of the International Association of Biological Standardization
M Le Hanneur, C Vidal, C Mallet, K Mazda, B Ilharreborde
A 32-month-old boy presented with febrile limping that had developed over 6days, associated with right lumbosacral inflammatory swelling. Magnetic resonance imaging (MRI) showed joint effusion of the right L5-S1 zygapophyseal joint, complicated by destructive osteomyelitis of the L5 articular process and paraspinal abscess. Surgery was decided to evacuate the fluid accumulation and rule out differential diagnoses. The diagnosis of septic arthritis of the facet joint was confirmed intraoperatively; real-time quantitative PCR analysis identified Kingella kingae...
September 14, 2016: Orthopaedics & Traumatology, Surgery & Research: OTSR
James Mallet, Hopi E Hoekstra
Mimicry and melanism in Lepidoptera provided the first convincing examples of natural selection in action. Genetic analysis has now shown that, surprisingly, mimicry in Heliconius butterflies and melanism in peppered moths are switched at precisely the same gene: cortex.
September 12, 2016: Current Biology: CB
Justin D Mallet, Marie M Dorr, Marie-Catherine Drigeard Desgarnier, Nathalie Bastien, Sébastien P Gendron, Patrick J Rochette
Absorption of UV rays by DNA generates the formation of mutagenic cyclobutane pyrimidine dimers (CPD) and pyrimidine (6-4) pyrimidone photoproducts (6-4PP). These damages are the major cause of skin cancer because in turn, they can lead to signature UV mutations. The eye is exposed to UV light, but the cornea is orders of magnitude less prone to UV-induced cancer. In an attempt to shed light on this paradox, we compared cells of the corneal epithelium and the epidermis for UVB-induced DNA damage frequency, repair and cell death sensitivity...
2016: PloS One
Shaheena Parween, Florence Roucher Boulez, Christa E Flück, Anne Lienhardt-Roussie, Delphine Mallet, Yves Morel, Amit V Pandey
CONTEXT: P450 oxidoreductase (POR) is required for the activities of steroid metabolizing cytochrome P450 enzymes in the endoplasmic reticulum. P450 oxidoreductase deficiency (PORD) is a form of congenital adrenal hyperplasia. Objective and Aim: Enzymatic and structural analysis of a novel L374H POR mutation from a patient with 46, XX disorder of sexual development. Design, setting, patient and intervention: 46,XX girl with non-consanguineous Turkish parents. Virilized external genitalia at birth; uterus and ovaries present, no sign of Antley-Bixler syndrome...
September 7, 2016: Journal of Clinical Endocrinology and Metabolism
Vincent Mallet, Florian van Bömmel, Christopher Doerig, Sven Pischke, Olivier Hermine, Anna Locasciulli, Catherine Cordonnier, Thomas Berg, Darius Moradpour, Heiner Wedemeyer, Per Ljungman
Viral hepatitis affects millions of people worldwide, and host immunity is the key determinant of patient outcome. Viral hepatitis can be life threatening in patients with haematological malignancy, including haemopoietic stem cell transplant recipients, because of the virus itself, or through a need to decrease the dose of chemotherapy. A past or currently infected haemopoietic stem cell donor could also transmit viral hepatitis. The burden of viral hepatitis in patients with haematological malignancies and the weak evidence on which previous guidelines are based has prompted the European Conference on Infection in Leukaemia (ECIL-5) to convene a group of experts in the fields of viral hepatitis and of haematological malignancy to specifically address previously unconsidered issues and grade the available quality of evidence according to the Infectious Diseases Society of America grading system...
May 2016: Lancet Infectious Diseases
Yuin Cheng Chin, Tun-Lin Foo
We describe three steps to aid fracture assessment and fixation in the extensor block pin technique for mallet fractures. The first step is the use of fluoroscopy in the initial assessment to determine indication for fixation. Next is the use of supplementary extension block pin to control larger dorsal fragments. The third technique described details the steps of open reduction of nascently malunited fractures.
October 2016: J Hand Surg Asian Pac Vol
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