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https://www.readbyqxmd.com/read/28417701/survey-of-hand-surgeons-and-therapists-perceptions-of-the-benefit-of-common-surgical-procedures-of-the-hand
#1
Olli V Leppänen, Jarkko Jokihaara, Esa Jämsen, Teemu Karjalainen
OBJECTIVE: The objectives of this survey were (1) to study if surgeons' perceptions of the benefit of six surgical procedures differ if they consider themselves as patients instead of treating a patient, (2) to evaluate the role of five predetermined factors that may influence decision-making, and (3) to assess how uniformly hand surgeons and hand therapists perceive the benefits of the surgical treatments. METHODS: The members of the national societies for Hand Surgery and Hand Therapy were asked to participate in the survey...
April 18, 2017: Journal of Plastic Surgery and Hand Surgery
https://www.readbyqxmd.com/read/28416253/mechanical-stability-of-the-taper-connection-of-large-metal-femoral-heads-with-adapter-sleeves-in-total-hip-arthroplasty-analyzed-using-explicit-finite-element-simulations
#2
Danny Vogel, Adrian Falkenberg, Sarah Bierbaum, Christian Schulze, Rainer Bader, Daniel Kluess
BACKGROUND: Large diameter heads (LDHs) of metal-on-metal bearings in total hip arthroplasty provide increased range of motion and reduced dislocation rates. However, major concerns grew over high wear rates from the modular connection between femoral stem and head, especially in combination with adapter sleeves. METHODS: A computational study on the taper connection stability of LDH (50 mm) with adapter sleeves of different lengths (S, M, L, and XL) compared with a standard femoral head (32 mm) without adapter sleeves was conducted using explicit finite element analyses...
March 22, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28408046/-evaluation-of-practices-in-the-management-of-scabies-in-children
#3
M-S Lê, M-A Richard, K Baumstarck, S Hesse, C Gaudy-Marqueste, J-J Grob, S Mallet
BACKGROUND: Scabies has been on the rise in France in recent years and has posed therapeutic problems, mainly due to the withdrawal of benzyl benzoate. The objective of this study was to describe prescribing practices for scabies in children. METHODS: A national survey was conducted by means of a standardized questionnaire covering various clinical situations of scabies and the drugs used preferentially according to age, which was sent out between December 2014 and March 2015 to members of the clinical research group of the French Society of Paediatric Dermatology...
April 10, 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/28399152/tackling-psychosocial-maladjustment-in-parkinson-s-disease-patients-following-subthalamic-deep-brain-stimulation-a-randomised-clinical-trial
#4
Joao Flores Alves Dos Santos, Sophie Tezenas du Montcel, Marcella Gargiulo, Cecile Behar, Sébastien Montel, Thierry Hergueta, Soledad Navarro, Hayat Belaid, Pauline Cloitre, Carine Karachi, Luc Mallet, Marie-Laure Welter
BACKGROUND: Subthalamic nucleus deep brain stimulation (STN-DBS) is an effective treatment for the motor and non-motor signs of Parkinson's disease (PD), however, psychological disorders and social maladjustment have been reported in about one third of patients after STN-DBS. We propose here a perioperative psychoeducation programme to limit such social and familial disruption. METHODS: Nineteen PD patients and carers were included in a randomised single blind study...
2017: PloS One
https://www.readbyqxmd.com/read/28396173/contribution-of-alcohol-use-disorders-on-the-burden-of-chronic-hepatitis-c-in-france-2008-2013-a-nationwide-retrospective-cohort-study
#5
Michaël Schwarzinger, Sylvain Baillot, Prof Yazdan Yazdanpanah, Prof Jürgen Rehm, Vincent Mallet
BACKGROUND AND AIMS: Hepatitis C virus (HCV) patients are at risk of alcohol use disorders (AUDs). We measured the contribution of AUDs on the burden of chronic HCV infection in French HCV patients. METHODS: We tracked the hospital trajectory of 97,347 French HCV patients aged 18-65 in January 2008 and followed until in-hospital death or December 2013. Primary outcome was the frequency of liver-related complications. Secondary outcomes were the frequency of liver transplantation and otherwise cause-specific mortality...
April 7, 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/28394871/triplanar-humeral-osteotomy-for-restoration-of-midline-function-in-patients-with-brachial-plexus-birth-palsy
#6
John D Jennings, Dustin A Greenhill, Scott H Kozin, Dan A Zlotolow
Brachial plexus birth palsy resolves spontaneously in a majority of patients, however, others may have serious permanent dysfunction. Although nerve transfers or grafts are early options for treatment, many children have residual deficits or present too late for such procedures. In these patients, rotational osteotomy of the humerus may restore improved function and motion. Unfortunately, traditional humeral osteotomies only provide correction in a single plane, therefore appropriate correction of the typical residual deformity is incomplete...
April 7, 2017: Techniques in Hand & Upper Extremity Surgery
https://www.readbyqxmd.com/read/28394805/factors-associated-with-fecal-incontinence-in-women-of-childbearing-age-with-crohn-s-disease
#7
Charlène Brochard, Laurent Siproudhis, Jean Levêque, Amélie Grouin, Anne-Laure Mallet, Jean-François Bretagne, Alain Ropert, Guillaume Bouguen
BACKGROUND: Fecal incontinence is common in women with Crohn's disease, but little is known about the impact of childbirth, perianal Crohn's disease, and past surgical history on fecal incontinence. METHODS: Self-administered questionnaires were mailed to consecutive women referred to a tertiary gastroenterology centre with a focus on fecal incontinence and childbirth. These data were cross-referenced with a prospective database of the same patients' own Crohn's disease histories...
May 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28390408/a-comprehensive-hybridization-model-allows-whole-herv-transcriptome-profiling-using-high-density-microarray
#8
Jérémie Becker, Philippe Pérot, Valérie Cheynet, Guy Oriol, Nathalie Mugnier, Marine Mommert, Olivier Tabone, Julien Textoris, Jean-Baptiste Veyrieras, François Mallet
BACKGROUND: Human endogenous retroviruses (HERVs) have received much attention for their implications in the etiology of many human diseases and their profound effect on evolution. Notably, recent studies have highlighted associations between HERVs expression and cancers (Yu et al., Int J Mol Med 32, 2013), autoimmunity (Balada et al., Int Rev Immunol 29:351-370, 2010) and neurological (Christensen, J Neuroimmune Pharmacol 5:326-335, 2010) conditions. Their repetitive nature makes their study particularly challenging, where expression studies have largely focused on individual loci (De Parseval et al...
April 8, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28389889/nicotine-dependence-is-associated-with-depression-and-childhood-trauma-in-smokers-with-schizophrenia-results-from-the-face-sz-dataset
#9
Romain Rey, Thierry D'Amato, Laurent Boyer, Lore Brunel, Bruno Aouizerate, Fabrice Berna, Delphine Capdevielle, Isabelle Chereau, Gabrielle Chesnoy-Servanin, Hélène Denizot, Jean-Michel Dorey, Caroline Dubertret, Julien Dubreucq, Catherine Faget, Franck Gabayet, Christophe Lancon, Jasmina Mallet, David Misdrahi, Christine Passerieux, Aurélie Schandrin, Franck Schürhoff, Mathieu Urbach, Pierre Vidailhet, Pierre-Michel Llorca, Guillaume Fond
In a perspective of personalized care for smoking cessation, a better clinical characterization of smokers with schizophrenia (SZ) is needed. The objective of this study was to determine the clinical characteristics of SZ smokers with severe nicotine (NIC) dependence. 240 stabilized community-dwelling SZ smokers (mean age = 31.9 years, 80.4% male gender) were consecutively included in the network of the FondaMental Expert Centers for Schizophrenia and assessed with validated scales. Severe NIC dependence was defined by a Fagerstrom questionnaire score ≥ 7...
April 7, 2017: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/28387233/north-andean-origin-and-diversification-of-the-largest-ithomiine-butterfly-genus
#10
Donna Lisa De-Silva, Luísa L Mota, Nicolas Chazot, Ricardo Mallarino, Karina L Silva-Brandão, Luz Miryam Gómez Piñerez, André V L Freitas, Gerardo Lamas, Mathieu Joron, James Mallet, Carlos E Giraldo, Sandra Uribe, Tiina Särkinen, Sandra Knapp, Chris D Jiggins, Keith R Willmott, Marianne Elias
The Neotropics harbour the most diverse flora and fauna on Earth. The Andes are a major centre of diversification and source of diversity for adjacent areas in plants and vertebrates, but studies on insects remain scarce, even though they constitute the largest fraction of terrestrial biodiversity. Here, we combine molecular and morphological characters to generate a dated phylogeny of the butterfly genus Pteronymia (Nymphalidae: Danainae), which we use to infer spatial, elevational and temporal diversification patterns...
April 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28386409/low-statistical-power-in-biomedical-science-a-review-of-three-human-research-domains
#11
Estelle Dumas-Mallet, Katherine S Button, Thomas Boraud, Francois Gonon, Marcus R Munafò
Studies with low statistical power increase the likelihood that a statistically significant finding represents a false positive result. We conducted a review of meta-analyses of studies investigating the association of biological, environmental or cognitive parameters with neurological, psychiatric and somatic diseases, excluding treatment studies, in order to estimate the average statistical power across these domains. Taking the effect size indicated by a meta-analysis as the best estimate of the likely true effect size, and assuming a threshold for declaring statistical significance of 5%, we found that approximately 50% of studies have statistical power in the 0-10% or 11-20% range, well below the minimum of 80% that is often considered conventional...
February 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28365638/where-did-the-acute-medical-trainees-go-a-review-of-the-career-pathways-of-acute-care-common-stem-acute-medical-trainees-in-london
#12
Mark Mallet, Mike Jones
No abstract text is available yet for this article.
April 2017: Clinical Medicine: Journal of the Royal College of Physicians of London
https://www.readbyqxmd.com/read/28361585/pyruvate-preserves-antiglycation-defenses-in-porcine-brain-after-cardiac-arrest
#13
Gary F Scott, Anh Q Nguyen, Brandon H Cherry, Roger A Hollrah, Isabella Salinas, Arthur G Williams, Myoung-Gwi Ryou, Robert T Mallet
Cardiac arrest (CA) and cardiocerebral resuscitation (CCR)-induced ischemia-reperfusion imposes oxidative and carbonyl stress that injures the brain. The ischemic shift to anaerobic glycolysis, combined with oxyradical inactivation of glyceraldehyde 3-phosphate dehydrogenase (GAPDH), provokes excessive formation of the powerful glycating agent, methylglyoxal. The glyoxalase (GLO) system, comprising the enzymes glyoxalase 1 (GLO1) and GLO2, utilizes reduced glutathione (GSH) supplied by glutathione reductase (GR) to detoxify methylglyoxal resulting in reduced protein glycation...
January 1, 2017: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/28350557/double-versus-single-tendon-transfers-to-improve-shoulder-function-in-brachial-plexus-birth-palsy
#14
Dustin A Greenhill, William R Smith, F V Ramsey, Scott H Kozin, Dan A Zlotolow
BACKGROUND: In children with brachial plexus birth palsy (BPBP) undergoing tendon transfers to augment shoulder external rotation, it is unclear whether transfer of the latissimus dorsi with its combined latissimus dorsi and teres major (cLT) versus isolated teres major (iTM) tendon transfer yield different outcomes. METHODS: Records of patients with BPBP who underwent shoulder tendon transfers to augment external rotation were retrospectively reviewed. Transfer type (cLT or iTM) was considered indiscriminate by virtue of surgeon preference...
March 27, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28349247/benzodiazepine-long-term-administration-is-associated-with-impaired-attention-working-memory-in-schizophrenia-results-from-the-national-multicentre-face-sz-data-set
#15
Guillaume Fond, F Berna, L Boyer, O Godin, L Brunel, M Andrianarisoa, B Aouizerate, D Capdevielle, I Chereau, J M Danion, C Dubertret, J Dubreucq, C Faget, F Gabayet, T Le Gloahec, P M Llorca, J Mallet, D Misdrahi, R Rey, R Richieri, C Passerieux, C Portalier, P Roux, A Vehier, H Yazbek, F Schürhoff, E Bulzacka
OBJECTIVE: The effect of benzodiazepine long-term administration (BLTA) in cognitive functioning of subjects with schizophrenia (SZ) has been partially explored to date. The objective was to assess BLTA-associated cognitive impairment with a comprehensive cognitive battery in a non-selected multicentric/national community-dwelling sample of stabilized SZ subjects. METHOD: 407 community-dwelling stabilized SZ subjects were consecutively included in the FondaMental Academic Centers of Expertise for Schizophrenia Cohort (FACE-SZ)...
March 27, 2017: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/28347577/utility-of-ultrasound-guided-injection-of-botulinum-toxin-type-a-for-muscle-imbalance-in-children-with-obstetric-brachial-plexus-palsy-description-of-the-procedure-and-action-protocol
#16
A García Ron, R Gallardo, B Huete Hernani
INTRODUCTION: Obstetric brachial plexus palsy (OBPP) usually has a favourable prognosis. However, nearly one third of all severe cases have permanent sequelae causing a high level of disability. In this study, we explore the effectiveness of ultrasound-guided injection of botulinum toxin A (BoNT-A) and describe the procedure. PATIENTS AND METHODS: We designed a prospective, descriptive study including patients with moderate to severe OBPP who were treated between January 2010 and December 2014...
March 24, 2017: Neurología: Publicación Oficial de la Sociedad Española de Neurología
https://www.readbyqxmd.com/read/28325432/wide-awake-ultrasound-guided-percutaneous-extensor-central-slip-tenotomy-for-chronic-mallet-finger-a-prospective-study-of-14-cases-with-videos
#17
T Apard, G Candelier
The central slip tenotomy described by Fowler is an effective option for treating chronic mallet finger in order to avoid swan neck deformity of the finger. In a prospective study of 14 cases (13 failures of conservative treatment and one case of untreated mallet finger), we performed percutaneous ultrasound-guided central slip tenotomy with a 19 G needle using the wide-awake local anesthesia and no tourniquet (WALANT) technique. The mean extensor lag before surgery was 28° (range 20°-40°) and three patients had a swan neck deformity...
April 2017: Hand Surgery and Rehabilitation
https://www.readbyqxmd.com/read/28299267/postsurgical-consequences-in-lower-third-molar-surgical-extraction-using-micromotor-and-piezosurgery
#18
Freddy Kersi Mistry, Nidarsh Diwakar Hegde, Mithra Nidarsh Hegde
BACKGROUND: One of the most critical and crucial steps in surgical extraction is cutting the bone or osteotomy, for which many techniques are used, e.g., chisels and mallet, rotary instruments, and ultrasound bone-cutting instruments. If they are not used judiciously, they can be hazardous. OBJECTIVES: To assess the efficiency of piezosurgery unit over micromotor while performing surgical extraction of lower third molars by assessing the time taken for the surgery and measuring postoperative parameters such as pain, trismus, and swelling...
July 2016: Annals of Maxillofacial Surgery
https://www.readbyqxmd.com/read/28284450/erratum-to-prognosis-of-patients-with-chronic-hepatitis-b-in-france-2008-2013-a-nationwide-observational-and-hospital-based-study
#19
Vincent Mallet, Kamal Hamed, Michaël Schwarzinger
No abstract text is available yet for this article.
March 8, 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/28274605/the-outcomes-of-extension-block-pinning-and-nonsurgical-management-for-mallet%C3%A2-fracture
#20
Jun O Yoon, Hyungki Baek, Jae Kwang Kim
PURPOSE: We aimed to compare the clinical and radiographic results of patients with a mallet fracture involving more than one-third of the articular surface, but without a high degree of distal interphalangeal (DIP) joint subluxation, treated with extension block pinning or nonsurgical management. METHODS: Forty-nine patients with a mallet fracture involving more than one-third of the articular surface were reviewed. Twenty-six cases were treated using extension block pinning (surgery group) and 23 were treated nonsurgically (nonsurgical group)...
March 5, 2017: Journal of Hand Surgery
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