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Madeleine S Power, Neil Small, Bob Doherty, Barbara Stewart-Knox, Kate E Pickett
Food insecurity is a determinant of maternal health; however, research on the health impact of food insecurity among mothers of varying ethnicities is under-developed. We assessed the association of food insecurity and health among white British and Pakistani mothers. Data from the Born in Bradford cohort were matched with data on food insecurity and self-reported health from the nested BiB1000 study (N = 1280). Food insecurity was associated with elevated odds of fair/poor health among white British mothers but not Pakistani mothers...
March 19, 2018: European Journal of Public Health
Minseok Kwon, Sangseob Leem, Joon Yoon, Taesung Park
BACKGROUND: With the rapid advancement of array-based genotyping techniques, genome-wide association studies (GWAS) have successfully identified common genetic variants associated with common complex diseases. However, it has been shown that only a small proportion of the genetic etiology of complex diseases could be explained by the genetic factors identified from GWAS. This missing heritability could possibly be explained by gene-gene interaction (epistasis) and rare variants. There has been an exponential growth of gene-gene interaction analysis for common variants in terms of methodological developments and practical applications...
March 19, 2018: BMC Systems Biology
Theodosios S Papavramidis, George Stavrou, Pyrros Papakostas, Vasilis Grosomanidis, Smaro Kokkota, Antonios Michalopoulos, George Kolios, Katerina Kotzampassi
BACKGROUND: The BioEnterics Intragastric Balloon [BIB] is a reliable, non-invasive technique to manage obesity for subjects who refuse or are unsuitable for bariatric surgery. In a prior study, BIB placed in the antrum [A] was found to have significantly better results on weight loss in relation to that in fundus [F], but many balloons initially placed in the F were eventually found in the A. The aim of the present analysis was to evaluate whether the balloon position [firmly in F, firmly in A, or transient from F to A [FA]] influences the 3- and 6-month weight loss...
March 4, 2018: Obesity Surgery
Kuaibing Wang, Xiaoran Cao, Saier Wang, Wenjia Zhao, Jiangyan Xu, Zikai Wang, Hua Wu
Synthesizing kinetically stable coordination polymers (CPs) through ligand functionalization can effectively improve their supercapacitive performances. Herein, we have successfully synthesized three novel and topological Co-CPs by variation of flexible N-donor ligand and inorganic anions, namely interpenetrated [Co(HTATB)(o-bib)]•H2O, extended 2D layered Co(HTATB)(m-bib)•2H2O and 3D Co(HTATB)(m-bib), where bib is the flexibly N-donor bis((1H-imidazol-1-yl)methyl)benzene linker (o- and m- means ortha- and metra- separately) and HTATB is the deprotonation mode from 4,4',4''-s-triazine-2,4,6-triyl-tribenzoicacid (H3TATB)...
February 15, 2018: ACS Applied Materials & Interfaces
Catriona Firth, Emily Petherick, Sam J Oddie
OBJECTIVE: We aimed to assess Child Death Overview Panel (CDOP) data validity, and cause of death classification, by comparison with information from a local birth cohort study (Born in Bradford, BiB), and another cause of death coding system (causes of death and associated conditions-CODAC). We then aimed to use CDOP data to calculate ethnic-specific infant mortality rates (IMRs), and compare characteristics of infants who died of congenital anomalies (CA) with those who died from other causes (non-CA)...
February 7, 2018: Archives of Disease in Childhood
Alex Alexandridis, Marios Stogiannos, Nikolaos Papaioannou, Elias Zois, Haralambos Sarimveis
This paper presents a novel methodology of generic nature for controlling nonlinear systems, using inverse radial basis function neural network models, which may combine diverse data originating from various sources. The algorithm starts by applying the particle swarm optimization-based non-symmetric variant of the fuzzy means (PSO-NSFM) algorithm so that an approximation of the inverse system dynamics is obtained. PSO-NSFM offers models of high accuracy combined with small network structures. Next, the applicability domain concept is suitably tailored and embedded into the proposed control structure in order to ensure that extrapolation is avoided in the controller predictions...
January 22, 2018: Sensors
N Moreira, P Lopes, H Ferreira, M Cabral, P Guedes de Pinho
The aim of this work was to study the effect of different configurations of packaging on the volatile composition and sensory properties of a white wine. Certain oenological parameters were also evaluated. Bag-in-box (BIB) and glass bottles sealed with two different cork stoppers, natural and Neutrocork (technical), were used in the experiments. Analysis were carried out before packaging and after 3, 6 and 12 months of storage. Results showed that wines packaged in BIB presented higher levels of brown color than wines in bottles sealed with corks...
January 2018: Journal of Food Science and Technology
Christopher R Friesen, Rasmus Johansson, Mats Olsson
Polymorphism has fascinated biologists for over a century because morphs persist within populations through evolutionary time in spite of showing disparate behavioral and physiological phenotypes; any one morph should go to fixation with the slightest fitness advantage over the others. Surely there must be trade-offs that balance selection on them. The polychromatic morphs of the Australian painted dragon lizard, Ctenophorus pictus, are one such system. The male color morphs of painted dragons have different physiological and behavioral traits including reproductive tactics, hormone levels, and the rate of body condition loss through the reproductive season...
August 2017: Journal of Experimental Zoology. Part A, Ecological and Integrative Physiology
Mohamad Kourghi, Jinxin V Pei, Michael L De Ieso, Saeed Nourmohammadi, Pak Hin Chow, Andrea J Yool
Aquaporin (AQP) channels in the major intrinsic protein (MIP) family are known to facilitate transmembrane water fluxes in prokaryotes and eukaryotes. Some classes of AQPs also conduct ions, glycerol, urea, CO2 , nitric oxide, and other small solutes. Ion channel activity has been demonstrated for mammalian AQPs 0, 1, 6, Drosophila Big Brain (BIB), soybean nodulin 26, and rockcress AtPIP2;1. More classes are likely to be discovered. Newly identified blockers are providing essential tools for establishing physiological roles of some of the AQP dual water and ion channels...
November 29, 2017: Clinical and Experimental Pharmacology & Physiology
Jing-Wang Cui, Suo-Xia Hou, Yue-Hua Li, Guang-Hua Cui
Herein, a nickel coordination polymer (CP 1), {Ni(1,4-bib)1.5 (TPA-Cl2 )·H2 O}n (1,4-bib = 1,4-bis(1H-imidazol-1-yl)benzene, H2 TPA-Cl2 = 2,5-dichloro-terephthalic acid), has been synthesized under solvothermal conditions. The structure of CP 1 is a 3D 3-fold interpenetrating framework with the sqc12 topology. The thermal stability and luminescence properties of CP 1 were investigated. Scanning electron microscopy (SEM) images of this material display that it possesses an irregular block 3D structure. Interestingly, CP 1 can serve as a multifunctional material via its luminescence sensing, electrochemical sensing, and photocatalytic properties...
December 12, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
Denise Lica Yoshimura Mikami, Cristina Lemos Barbosa Furia, Alexis Fonseca Welker
OBJECTIVE: To evaluate the effects of Kinesio Taping (KT) of the orbicularis oris muscles as an adjunct to standard therapy for drooling. METHODS: Fifteen children with neurological disorders and drooling received speech therapy and twice-weekly KT of the orbicularis muscles over a 30-day period. Drooling was assessed by six parameters: impact on the life of the child and caregiver; severity of drooling; frequency of drooling; drooling volume (estimated by number of bibs used); salivary leak; and interlabial gap...
September 21, 2017: Developmental Neurorehabilitation
Melchiorre Cervello, Giovanna Pitarresi, Antonella Bavuso Volpe, Barbara Porsio, Daniele Balasus, Maria Rita Emma, Antonina Azzolina, Roberto Puleio, Guido Ruggero Loria, Stefano Puleo, Gaetano Giammona
In this paper, we describe the preparation of polymeric nanoparticles (NPs) loaded with sorafenib for the treatment of hepatocellular carcinoma (HCC). A synthetic brush copolymer, named PHEA-BIB-ButMA (PBB), was synthesized by Atom Trasnfer Radical Polymerization (ATRP) starting from the α-poly(N-2-hydroxyethyl)-d,l-aspartamide (PHEA) and poly butyl methacrylate (ButMA). Empty and sorafenib loaded PBB NPs were, then, produced by using a dialysis method and showed spherical morphology, colloidal size, negative ζ potential and the ability to allow a sustained sorafenib release in physiological environment...
November 28, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
Man-Li Yue, Yi-Fan Jiang, Lin Zhang, Cheng-Yan Yu, Kang-Yu Zou, Zuo-Xi Li
In this work, five new cadmium metal-organic frameworks (Cd-MOFs 1-5) have been synthesized from solvothermal reactions of Cd(NO3 )2 ⋅4 H2 O with isophthalic acid and 1,4-bis(imidazol-1-yl)-benzene under different solvent systems of CH3 OH, C2 H5 OH, (CH3 )2 CHOH, DMF, and N-methyl-2-pyrrolidone (NMP), respectively. Cd-MOF 1 shows a 3D diamondoid framework with 1D rhombic and hexagonal channels, and the porosity is 12.9 %. Cd-MOF 2 exhibits a 2D (4,4) layer with a 1D parallelogram channel and porosity of 23...
August 7, 2017: Chemistry: a European Journal
Nicky Rollings, Christopher R Friesen, Joanna Sudyka, Camilla Whittington, Mathieu Giraudeau, Mark Wilson, Mats Olsson
Telomeres in human fibroblasts shorten progressively during in vitro culturing and trigger replicative senescence. Furthermore, shortened telomeres can be used as biomarkers of disease. These observations have led to the suggestion that telomere dynamics may also be associated with viability and selection for life history variation in non-human taxa. Model systems to examine this suggestion would particularly benefit from the coexistence of multiple phenotypes within the same species with different life history trade-offs, since those could be compared in terms of telomere characteristics...
July 2017: Ecology and Evolution
Ulrika Lind, Michael Järvå, Magnus Alm Rosenblad, Piero Pingitore, Emil Karlsson, Anna-Lisa Wrange, Emelie Kamdal, Kristina Sundell, Carl André, Per R Jonsson, Jon Havenhand, Leif A Eriksson, Kristina Hedfalk, Anders Blomberg
Barnacles are sessile macro-invertebrates, found along rocky shores in coastal areas worldwide. The euryhaline bay barnacle Balanus improvisus (Darwin, 1854) (= Amphibalanus improvisus) can tolerate a wide range of salinities, but the molecular mechanisms underlying the osmoregulatory capacity of this truly brackish species are not well understood. Aquaporins are pore-forming integral membrane proteins that facilitate transport of water, small solutes and ions through cellular membranes, and that have been shown to be important for osmoregulation in many organisms...
2017: PloS One
Hitoshi Tsujimoto, Joyce M Sakamoto, Jason L Rasgon
The bed bug Cimex lectularius is a blood-feeding re-emerging annoyance pest insect that has the ability to transmit Trypanosoma cruzi under experimental laboratory conditions. Aquaporins (AQPs) are water channel proteins that are essential in biological organisms. C. lectularius are constantly exposed to water-related stress, suggesting that AQPs may offer novel control avenues. We identified and cloned four AQPs from C. lectularius, assessed tissue and lifestage-specific expression, and characterized biochemical functions in vitro and in vivo...
June 12, 2017: Scientific Reports
Francesco Sadile, Alessio Bernasconi, Nicola Maffulli
PURPOSE: To date, four synovial plicae are classically described in the knee. We report a previously undescribed new inferior patellar plica, named "bib-like plica" (BLP, referring to its morphology) related to specific symptoms of atypical recurrent anterior knee pain in the presence of a locked or pseudo-locked knee. We describe this anatomical structure, and assess its clinical relevance in daily practice in terms of clinical pattern and long-term follow-up outcome after arthroscopic excision...
June 8, 2017: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
Ismael Galván, Carlos Alonso-Alvarez
The evolution of honest animal communication is mostly understood through the handicap principle, which is intrinsically dependent on the concept of individual quality: low-quality individuals are prevented from producing high-quality signals because if they did so, they would pay greater production costs than high-quality individuals. We tested an alternative explanation for the black bib size of male house sparrows Passer domesticus, an honest signal of quality whose expression is negatively related to levels of the pigment pheomelanin in its contituent feathers...
May 25, 2017: Journal of Experimental Biology
Kang-Yu Zou, Yi-Chen Liu, Yi-Fan Jiang, Cheng-Yan Yu, Man-Li Yue, Zuo-Xi Li
Herein three novel cobalt metal-organic frameworks (Co-MOFs) with similar ingredients, [Co(bib)(o-bdc)]∞ (1), [Co2(bib)2(m-bdc)2]∞ (2), and {[Co(bib)(p-bdc)(H2O)](H2O)0.5}∞ (3), have been synthesized from the reaction of cobalt nitrate with 1,4-bis(imidazol-1-yl)benzene (bib) and structure-related aromatic acids (1,2-benzenedicarboxylic acid = o-bdc, 1,3-benzenedicarboxylic acid = m-bdc, and 1,4-benzenedicarboxylic acid = p-bdc) by the solvothermal method. It is aimed to perform systematic research on the relationship among the conformation of benzoate acid, lattice dimension of Co-MOF, and pore diameter of MOF-derived carbon composite...
May 19, 2017: Inorganic Chemistry
C S McDiarmid, C R Friesen, C Ballen, M Olsson
Theory predicts trade-offs between pre- and post-copulatory sexually selected traits. This relationship may be mediated by the degree to which males are able to monopolize access to females, as this will place an upper limit on the strength of post-copulatory selection. Furthermore, traits that aid in mate monopolization may be costly to maintain and may limit investment in post-copulatory traits, such as sperm performance. Australian painted dragons are polymorphic for the presence or absence of a yellow gular patch ('bibs'), which may aid them to monopolize access to females...
April 20, 2017: Journal of Evolutionary Biology
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