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https://www.readbyqxmd.com/read/29675082/susac-s-syndrome-retinocochleocerebral-vasculopathy-follow-up-of-a-pediatric-patient
#1
Zeynep Selen Karalok, Birce Dilge Taskin, Alev Guven, Cemile Atilgan Ucgul, Omer Faruk Aydin
Susac's syndrome (SS) is a triad of encephalopathy, branch retinal artery occlusion (BRAO), and sensorineural hearing loss as a result of microvascular occlusions of the brain, retina, and inner ear. It is also a disorder of autoimmune endotheliopathy. SS usually affects young women between the age of 20 and 40 years. SS can be misdiagnosed as multiple sclerosis (MS) or acute disseminated encephalomyelitis (ADEM) because of similar findings. A 15-year-old girl presented in June 2015 with vomiting and severe headache...
October 2017: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/29673575/classification-and-diagnostic-criteria-for-demyelinating-diseases-of-the-central-nervous-system-where-do-we-stand-today
#2
REVIEW
G Mathey, M Michaud, S Pittion-Vouyovitch, M Debouverie
The diagnosis of multiple sclerosis (MS) and other demyelinating diseases of the central nervous system is challenging, and although the currently available biological and imaging tools offer considerable support to physicians, these tools often fail to provide a simple and final answer at the time of a first event. Thus, sets of diagnostic criteria have been published and tested on patient cohorts, and are now used in clinical trials and in daily clinical practice. These criteria have evolved over time to take into account physicians' and patients' needs, along with emerging paraclinical tests...
April 16, 2018: Revue Neurologique
https://www.readbyqxmd.com/read/29669224/evaluation-of-intussusception-after-monovalent-rotavirus-vaccination-in-africa
#3
Jacqueline E Tate, Jason M Mwenda, George Armah, Bhavin Jani, Richard Omore, Ayesheshem Ademe, Hilda Mujuru, Evans Mpabalwani, Bagrey Ngwira, Margaret M Cortese, Richard Mihigo, Hope Glover-Addy, Mwajabu Mbaga, Francis Osawa, Amezene Tadesse, Bothwell Mbuwayesango, Julia Simwaka, Nigel Cunliffe, Benjamin A Lopman, Goitom Weldegebriel, Daniel Ansong, David Msuya, Billy Ogwel, Thomas Karengera, Portia Manangazira, Bruce Bvulani, Catherine Yen, Felicitas R Zawaira, Clement T Narh, Lazaro Mboma, Peter Saula, Fasil Teshager, Halle Getachew, Rebecca M Moeti, Christabel Eweronu-Laryea, Umesh D Parashar
BACKGROUND: Postlicensure evaluations have identified an association between rotavirus vaccination and intussusception in several high- and middle-income countries. We assessed the association between monovalent human rotavirus vaccine and intussusception in lower-income sub-Saharan African countries. METHODS: Using active surveillance, we enrolled patients from seven countries (Ethiopia, Ghana, Kenya, Malawi, Tanzania, Zambia, and Zimbabwe) who had intussusception that met international (Brighton Collaboration level 1) criteria...
April 19, 2018: New England Journal of Medicine
https://www.readbyqxmd.com/read/29668490/low-dose-mirtazapine-in-major-depression-developed-after-hyperemesis-gravidarum-a-case-series
#4
Faruk Uguz, Keziban Turgut, Adem Aydin, Mehmet Ak
No abstract text is available yet for this article.
April 9, 2018: American Journal of Therapeutics
https://www.readbyqxmd.com/read/29661590/rituximab-was-effective-for-acute-disseminated-encephalomyelitis-followed-by-recurrent-optic-neuritis-with-anti-myelin-oligodendrocyte-glycoprotein-antibodies
#5
Masako Nagashima, Hitoshi Osaka, Takahiro Ikeda, Ayumi Matsumoto, Akihiko Miyauchi, Kimihiko Kaneko, Ichiro Nakashima, Yuko Nakano, Kei Wakabayashi, Yukifumi Monden, Takanori Yamagata
BACKGROUND: The effect of rituximab on acute disseminated encephalomyelitis (ADEM) followed by recurrent optic neuritis (ON) is not yet known. PATIENT: We are reporting the case of a 4-year-old Japanese girl who was diagnosed with anti-myelin oligodendrocyte glycoprotein (MOG) antibody positive ADEM followed by recurrent ON. She developed altered mental status, left facial paralysis, left paresis, and experienced three episodes of ON. She was treated with rituximab and azathioprine (AZA) as prevention for recurrent ON...
April 13, 2018: Brain & Development
https://www.readbyqxmd.com/read/29657951/distribution-of-thoracic-aortic-calcifications-in-patients-undergoing-coronary-artery-bypass-grafting
#6
Adem Ilkay Diken, Adnan Yalçınkaya, Sertan Özyalçın
Background: In procedures involving surgical maneuvers such as cannulation, clamping, or proximal anastomosis where aortic manipulation is inevitable, a preliminary assessment of atherosclerotic plaques bears clinical significance. In the present study, our aim was to evaluate the frequency and distribution of aortic calcifications in patients undergoing coronary artery bypass grafting (CABG) surgery to propose a morphological classification system. Methods: A total of 443 consecutive patients with coronary artery disease were included in this study...
October 2017: Aorta (Stamford, Conn.)
https://www.readbyqxmd.com/read/29656660/cytotoxic-flavonoids-from-two-lonchocarpus-species
#7
Fozia A Adem, Victor Kuete, Armelle T Mbaveng, Matthias Heydenreich, Andreas Koch, Albert Ndakala, Beatrice Irungu, Abiy Yenesew, Thomas Efferth
A new isoflavone, 4'-prenyloxyvigvexin A (1) and a new pterocarpan, (6aR,11aR)-3,8-dimethoxybitucarpin B (2) were isolated from the leaves of Lonchocarpus bussei and the stem bark of Lonchocarpus eriocalyx, respectively. The extract of L. bussei also gave four known isoflavones, maximaisoflavone H, 7,2'-dimethoxy-3',4'-methylenedioxyisoflavone, 6,7,3'-trimethoxy-4',5'-methylenedioxyisoflavone, durmillone; a chalcone, 4-hydroxylonchocarpin; a geranylated phenylpropanol, colenemol; and two known pterocarpans, (6aR,11aR)-maackiain and (6aR,11aR)-edunol...
April 16, 2018: Natural Product Research
https://www.readbyqxmd.com/read/29651411/-leishmania-antigenuria-to-predict-initial-treatment-failure-and-relapse-in-visceral-leishmaniasis-hiv-coinfected-patients-an-exploratory-study-nested-within-a-clinical-trial-in-ethiopia
#8
Johan van Griensven, Bewketu Mengesha, Tigist Mekonnen, Helina Fikre, Yegnasew Takele, Emebet Adem, Rezika Mohammed, Koert Ritmeijer, Florian Vogt, Wim Adriaensen, Ermias Diro
Background: Biomarkers predicting the risk of VL treatment failure and relapse in VL/HIV coinfected patients are needed. Nested within a two-site clinical trial in Ethiopia (2011-2015), we conducted an exploratory study to assess whether (1) levels of Leishmania antigenuria measured at VL diagnosis were associated with initial treatment failure and (2) levels of Leishmania antigenuria at the end of treatment (parasitologically-confirmed cure) were associated with subsequent relapse. Methods: Leishmania antigenuria at VL diagnosis and cure was determined using KAtex urine antigen test and graded as negative (0), weak/moderate (grade 1+/2+) or strongly-positive (3+)...
2018: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/29649265/bacterial-and-protozoal-pathogens-found-in-ticks-collected-from-humans-in-corum-province-of-turkey
#9
Djursun Karasartova, Ayse Semra Gureser, Tuncay Gokce, Bekir Celebi, Derya Yapar, Adem Keskin, Selim Celik, Yasemin Ece, Ali Kemal Erenler, Selma Usluca, Kosta Y Mumcuoglu, Aysegul Taylan-Ozkan
BACKGROUND: Tick-borne diseases are increasing all over the word, including Turkey. The aim of this study was to determine the bacterial and protozoan vector-borne pathogens in ticks infesting humans in the Corum province of Turkey. METHODOLOGY/PRINCIPAL FINDINGS: From March to November 2014 a total of 322 ticks were collected from patients who attended the local hospitals with tick bites. Ticks were screened by real time-PCR and PCR, and obtained amplicons were sequenced...
April 12, 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29644536/cigarette-smoke-and-nicotine-effects-on-brain-proinflammatory-responses-and-behavioral-and-motor-function-in-hiv-1-transgenic-rats
#10
Walter Royal, Adem Can, Todd D Gould, Ming Guo, Jared Huse, Myles Jackson, Harry Davis, Joseph Bryant
Cognitive impairment in HIV-1 infection is associated with the induction of chronic proinflammatory responses in the brains of infected individuals. The risk of HIV-related cognitive impairment is increased by cigarette smoking, which induces brain inflammation in rodent models. To better understand the role of smoking and the associated immune response on behavioral and motor function in HIV infection, wild-type F344 and HIV-1 transgenic (HIV1Tg) rats were exposed to either smoke from nicotine-containing (regular) cigarettes, smoke from nicotine-free cigarettes, or to nicotine alone...
April 11, 2018: Journal of Neurovirology
https://www.readbyqxmd.com/read/29627732/responses-of-grapevine-rootstocks-to-drought-through-altered-root-system-architecture-and-root-transcriptomic-regulations
#11
Kubilay Yıldırım, Adem Yağcı, Seda Sucu, Sümeyye Tunç
Roots are the major interface between the plant and various stress factors in the soil environment. Alteration of root system architecture (RSA) (root length, spread, number and length of lateral roots) in response to environmental changes is known to be an important strategy for plant adaptation and productivity. In light of ongoing climate changes and global warming predictions, the breeding of drought-tolerant grapevine cultivars is becoming a crucial factor for developing a sustainable viticulture. Root-trait modeling of grapevine rootstock for drought stress scenarios, together with high-throughput phenotyping and genotyping techniques, may provide a valuable background for breeding studies in viticulture...
March 31, 2018: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/29622911/submitral-left-ventricular-aneurysm-associated-with-thrombus
#12
Abdusamed Adem Abdusamed, Hailu Abera Mulatu, Reinaldo Nunez Martinez
Background: Submitral left ventricular aneurysm is a rarely reported cardiac abnormality that is encountered commonly among blacks. So far, only one case has been reported from Ethiopia and East Africa.Our aim is to report an interesting and rare case that we encountered at St. Paul's Hospital Millennium Medical College. Methods: In April 2017, a 25-year-old patient havingsubmitral left ventricular aneurysm with New York Heart Association (NYHA) class IV heart failure and mild left ventricular systolic dysfunctionreceived medical treatment at our institution...
January 2018: Ethiopian Journal of Health Sciences
https://www.readbyqxmd.com/read/29618927/serum-levels-of-gper-1-in-euthymic-bipolar-patients
#13
Fatma Özlem Orhan, Ergül Belge Kurutaş, Adem Doğaner, Ebru Türker, Safiye Şeyma Taner Özcü, Meltem Güngör, Seyfettin Çakmak
Introduction: Estrogen and its receptors have been suggested as playing a role in the pathogenesis of bipolar disorder (BD). Estrogen functions through the estrogen receptors alpha and beta and the recently discovered G-protein-coupled estrogen receptor-1 (GPER-1). The aim of this study was to evaluate serum GPER-1 levels in euthymic BD patients. Patients and methods: The study population consisted of 38 euthymic outpatients meeting the criteria for BD in the Diagnostic and Statistical Manual of Mental Disorders , Fifth Edition and 35 age- and gender-matched healthy controls...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29610571/efficacy-of-bilateral-transversus-abdominis-plane-and-ilioinguinal-iliohypogastric-nerve-blocks-for-postcaesarean-delivery-pain-relief-under-spinal-anesthesia
#14
Seid Adem Ahemed, Zewditu Abdissa Denu, Habtamu Getinet Kassahun, Demeke Yilikal Fentie
Background: Caesarean delivery can be associated with considerable postoperative pain. While the benefits of transversus abdominis plane (TAP) and ilioinguinal-iliohypogastric (II-IH) nerve blocks on pain after caesarean delivery via Pfannenstiel incision have been demonstrated, no enough investigations on the comparison of these blocks on pain after caesarean delivery have been conducted in our setup. Method: An institutional-based prospective observational cohort study was conducted to compare the analgesic efficacy of those blocks...
2018: Anesthesiology Research and Practice
https://www.readbyqxmd.com/read/29607427/urban-legend-or-real-fact-coronary-artery-size-varies-with-demographics
#15
Mustafa Adem Tatlisu, Murat Sargin, Adnan Kaya, Ahmet Ilker Tekkesin, Zekeriya Nurkalem, Serap Aykut Aka
OBJECTIVE: This study aimed to determine the relationship between the diameter of coronary artery stents and age, gender, diabetes mellitus (DM), left ventricular ejection fraction (LVEF), renal dysfunction, and the clinical presentation of myocardial ischemia in the cohort of patients with implanted stents in coronary arteries with severe stenotic lesions. METHODS: This study included 2256 patients (mean age, 59.3±10.9 years; men, 62%) who underwent percutaneous coronary intervention (PCI)...
2018: Northern Clinics of Istanbul
https://www.readbyqxmd.com/read/29591886/investigation-of-the-genotoxic-and-cytotoxic-effects-of-widely-used-neonicotinoid-insecticides-in-hepg2-and-sh-sy5y-cells
#16
Mine Şenyildiz, Adem Kilinc, Sibel Ozden
Neonicotinoids are a relatively new type of insecticide to control a variety of pests. Although they are generally considered to be safe, they can lead to harmful effects on human and environmental health. We aimed to investigate possible effects of common neonicotinoid insecticides (acetamiprid, clothianidin, imidacloprid, thiacloprid, and thiamethoxam) on cytotoxicity and DNA damage in human neuroblastoma (SH-SY5Y) and human hepatocellular carcinoma (HepG2) cells. Our results indicated that 50% of inhibitory concentration values of neonicotinoids are in the range of 0...
January 1, 2018: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/29589114/can-neck-pain-be-an-initial-symptom-of-rheumatoid-arthritis-a-case-report-and-literature-review
#17
REVIEW
Erdal Bodakçi, Döndü Üsküdar Cansu, Adem Ertürk, Cüneyt Çalişir, Cengiz Korkmaz
Although rheumatoid arthritis (RA) is most commonly associated with peripheral joints, cervical spine involvement can be seen in almost 80% of patients in the presence of long-term disease, joint erosion, and risk factors such as male sex and rheumatoid factor positivity. It is very rare to have cervical involvement in the initial period of RA. If a patient has isolated cervical spine involvement without peripheral arthritis, it is highly likely that inappropriate investigations and delayed treatment may occur...
March 27, 2018: Rheumatology International
https://www.readbyqxmd.com/read/29582659/cigarillo-and-little-cigar-mainstream-smoke-constituents-from-replicated-human-smoking
#18
Wallace Pickworth, Zachary R Rosenberry, Daniel Yi, Emily Pitts, Wilhelmina Lord-Adem, Bartosz Koszowski
Little cigar and cigarillo smoking is increasing in popularity in the U.S., but little is known about the topography and mainstream smoke (MSS) constituents of these types of cigar products. This report describes the quantity of selected MSS toxicants generated from puff-by-puff replication of human laboratory smoking. Participants were dual users of cigarettes and either little cigars (n=21) or cigarillos (n=23). In the laboratory smoking session, participants of the little cigar group smoked a filtered unflavored Winchester Little Cigar; those in the cigarillo group smoked an unfiltered, unflavored Black & Mild cigarillo...
March 27, 2018: Chemical Research in Toxicology
https://www.readbyqxmd.com/read/29574241/acute-disseminated-encephalomyelitis-a-rare-post-malaria-neurological-complication-case-report-and-review-of-the-literature
#19
REVIEW
Joana Carreira, Maria Isabel Casella, Bianca Branco Ascenção, Nuno Pinto Luis, Ana Catarina Gonçalves, Ana Paula Brito, Joana Estalagem Sá, Mário Parreira, Delfim Lopes, José Poças
There are four neurological complications that can occur after malaria treatment at a time when the patient is aparasitaemic: delayed cerebellar ataxia, acute inflammatory demyelinating polyneuropathy, post-malaria neurological syndrome and acute disseminated encephalomyelitis (ADEM). The authors describe a case of a 54-year-old male who presented with encephalopathy and generalized seizures forty-three days after complete recovery from acute malaria by Plasmodium falciparum. Diagnosis of post-malaria ADEM was made based on the acute onset of the neurological symptoms, characteristic findings in magnetic resonance imaging of the brain and prompt response to steroid therapy...
March 21, 2018: Travel Medicine and Infectious Disease
https://www.readbyqxmd.com/read/29572589/low-flow-anaesthesia-with-a-fixed-fresh-gas-flow-rate
#20
Seyma Bahar, Mahmut Arslan, Aykut Urfalioglu, Gokce Gisi, Gozen Oksuz, Bora Bilal, Hafize Oksuz, Adem Doganer
During the wash-in period in low flow anaesthesia (LFA), high fresh gas flow is used to achieve the desired agent concentration. In this study, we aimed to evaluate the safety of fixed 1 L/min fresh gas flow desflurane anaesthesia in both the wash-in and maintenance periods in patients including the obese ones. 104 patients undergoing surgery under general anaesthesia were included. After endotracheal intubation, fresh gas flow was reduced to 1 L/min and the desflurane vaporizer was set at 18%. The time from opening the vaporizer to end-tidal desflurane concentration reaching 0...
March 23, 2018: Journal of Clinical Monitoring and Computing
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