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https://www.readbyqxmd.com/read/28734837/neural-reuse-of-action-perception-circuits-for-language-concepts-and-communication
#1
REVIEW
Friedemann Pulvermüller
Neurocognitive and neurolinguistics theories make explicit statements relating specialized cognitive and linguistic processes to specific brain loci. These linking hypotheses are in need of neurobiological explanation. Recent mathematical models of human language mechanisms constrained by fundamental neuroscience principles and established knowledge about comparative neuroanatomy offer explanations for where, when and how language is processed in the human brain. In these models, network structure and connectivity along with action- and perception-induced correlation of neuronal activity co-determine neurocognitive mechanisms...
July 19, 2017: Progress in Neurobiology
https://www.readbyqxmd.com/read/28734549/habitual-versus-goal-driven-attention
#2
REVIEW
Yuhong V Jiang
Recent research has expanded the list of factors that control spatial attention. Beside current goals and perceptual salience, statistical learning, reward, motivation and emotion also affect attention. But do these various factors influence spatial attention in the same manner, as suggested by the integrated framework of attention, or do they target different aspects of spatial attention? Here I present evidence that the control of attention may be implemented in two ways. Whereas current goals typically modulate where in space attention is prioritized, search habits affect how one moves attention in space...
July 4, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28734172/clear-evidence-for-item-limits-in-visual-working-memory
#3
Kirsten C S Adam, Edward K Vogel, Edward Awh
There is a consensus that visual working memory (WM) resources are sharply limited, but debate persists regarding the simple question of whether there is a limit to the total number of items that can be stored concurrently. Zhang and Luck (2008) advanced this debate with an analytic procedure that provided strong evidence for random guessing responses, but their findings can also be described by models that deny guessing while asserting a high prevalence of low precision memories. Here, we used a whole report memory procedure in which subjects reported all items in each trial and indicated whether they were guessing with each response...
July 19, 2017: Cognitive Psychology
https://www.readbyqxmd.com/read/28734164/cognitive-strategies-in-the-mental-rotation-task-revealed-by-eeg-spectral-power
#4
Aaron L Gardony, Marianna D Eddy, Tad T Brunyé, Holly A Taylor
The classic mental rotation task (MRT; Shepard & Metzler, 1971) is commonly thought to measure mental rotation, a cognitive process involving covert simulation of motor rotation. Yet much research suggests that the MRT recruits both motor simulation and other analytic cognitive strategies that depend on visuospatial representation and visual working memory (WM). In the present study, we investigated cognitive strategies in the MRT using time-frequency analysis of EEG and independent component analysis. We scrutinized sensorimotor mu (µ) power reduction, associated with motor simulation, parietal alpha (pα) power reduction, associated with visuospatial representation, and frontal midline theta (fmθ) power enhancement, associated with WM maintenance and manipulation...
July 19, 2017: Brain and Cognition
https://www.readbyqxmd.com/read/28734078/associations-between-adolescent-cannabis-use-and-neuropsychological-decline-a-longitudinal-co-twin-control-study
#5
Madeline H Meier, Avshalom Caspi, Andrea Danese, Helen L Fisher, Renate Houts, Louise Arseneault, Terrie E Moffitt
AIMS: This study tested whether adolescents who used cannabis or met criteria for cannabis dependence showed neuropsychological impairment prior to cannabis initiation and neuropsychological decline from before to after cannabis initiation. DESIGN: A longitudinal co-twin control study. SETTING AND PARTICIPANTS: Participants were 1,989 twins from the Environmental Risk (E-Risk) Longitudinal Twin Study, a nationally representative birth cohort of twins born in England and Wales from 1994-1995...
July 22, 2017: Addiction
https://www.readbyqxmd.com/read/28733684/distinct-contributions-by-frontal-and-parietal-cortices-support-working-memory
#6
Wayne E Mackey, Clayton E Curtis
Although subregions of frontal and parietal cortex both contribute and coordinate to support working memory (WM) functions, their distinct contributions remain elusive. Here, we demonstrate that perturbations to topographically organized human frontal and parietal cortex during WM maintenance cause distinct but systematic distortions in WM. The nature of these distortions supports theories positing that parietal cortex mainly codes for retrospective sensory information, while frontal cortex codes for prospective action...
July 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28733668/two-visual-working-memory-representations-simultaneously-control-attention
#7
Yanan Chen, Feng Du
It has been proposed that only one visual working memory (VWM) representation can be activated to influence perception directly, whereas other VWM representations are accessory items which have little influence on visual selection. The sole active VWM representation might reflect a fundamental bottleneck in the information processing of human beings. However, the present study showed that each of two VWM representations can capture attention and interfere with concurrent visual search. In addition, each of two VWM representations can interfere with concurrent visual search as much as can a single cued VWM representation...
July 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28733256/prefrontal-neuromodulation-reverses-spatial-associations-of-non-numerical-sequences-but-not-numbers
#8
Philipp Alexander Schroeder, Hans-Christoph Nuerk, Christian Plewnia
Numerical and non-numerical sequence items interact with spatial responding, pointing towards mental representations that are grounded in space and referred to as SNARC effects (spatial-numerical association of response codes). An ongoing controversy pertains to the universal origin of different SNARC effects and whether their underpinning is a spatial arrangement of cardinal magnitude (mental number line) or a sequential arrangement of ordinal elements in working memory. Recent results from prefrontal neuromodulation with transcranial direct current stimulation (tDCS) were supportive of the unified working memory account...
July 18, 2017: Biological Psychology
https://www.readbyqxmd.com/read/28732260/differences-in-emotional-stimuli-processing-in-subjects-with-mtle-with-and-without-depression
#9
Lidija Preglej, Ksenija Marinković, Hrvoje Hećimović
In healthy people, a preference in attention maintenance and memory for words with emotional valence comparing to neutral words has been shown. The pattern of emotional stimuli processing may be different in people with mesial temporal lobe epilepsy (MTLE) and it may be sensitive to the presence of depressive symptoms. In order to explore these possibilities, we applied the emotional spatial cueing attentional task and the free recall memory task to participants (N=39) with MTLE and compared them with healthy controls...
July 18, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28731870/the-association-of-cognitive-reserve-in-chronic-phase-functional-and-neuropsychological-outcomes-following-traumatic-brain-injury
#10
Jacob B Leary, Grace Y Kim, Catherine L Bradley, Uzma Z Hussain, Maryanne Sacco, Martha Bernad, John Collins, John Dsurney, Leighton Chan
OBJECTIVE: Examine the association of cognitive reserve (CR) factors (estimated premorbid intelligence quotient [IQ], years of education, and occupational attainment) and traumatic brain injury (TBI) severity with functional and neuropsychological outcomes 1 to 5 years following TBI. PARTICIPANTS: Patients with mild (N = 58), moderate (N = 25), or severe (N = 17) TBI. MAIN MEASURES: Cognitive reserve factors (estimated premorbid IQ, years of education, and occupational attainment); neuropsychological test battery; Glasgow Outcome Scale-Extended; Short Form-36 Health Survey...
July 20, 2017: Journal of Head Trauma Rehabilitation
https://www.readbyqxmd.com/read/28731445/colivelin-ameliorates-impairments-in%C3%A2-cognitive-behaviors-and-synaptic-plasticity-in-app-ps1-transgenic-mice
#11
Meina Wu, Hui Shi, Yexin He, Li Yuan, Xuesong Qu, Jun Zhang, Zhaojun Wang, Hongyan Cai, Jinshun Qi
Alzheimer's disease (AD) is the most common cause of dementia, and effective therapeutics are lacking. Colivelin (CLN), a novel, strong humanin derivative, is effective in vitro in preventing cell death induced by AD-causative genes and amyloid-β protein (Aβ) even at a low concentration. We recently demonstrated that intrahippocampal injection of CLN prevents Aβ25-35-induced deficits in spatial memory and synaptic plasticity in normal rats. Here, we further observed the effects of chronically intranasally (i...
July 19, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28731437/computerized-cognitive-screen-cocosc-a-self-administered-computerized-test-for-screening-for-cognitive-impairment-in-community-social-centers
#12
Adrian Wong, Ching-Hang Fong, Vincent Mok, Kam Tat Leung, Raymond Kai-Yu Tong
BACKGROUND: Computerized cognitive tests may serve as a preliminary, low-cost method to identify individuals with suspected cognitive impairment in the community. OBJECTIVE: To develop a self-administered computerized test, namely the "Computerized Cognitive Screen (CoCoSc), Hong Kong version", for screening of individuals with cognitive impairment (CI) in community settings. METHODS: The CoCoSc is a 15-min computerized cognitive screen covering memory, executive functions, orientation, attention and working memory, and prospective memory administered on a touchscreen computer...
July 19, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28731436/impaired-processing-of-serial-order-determines-working-memory-impairments-in-alzheimer-s-disease
#13
Maya De Belder, Patrick Santens, Anne Sieben, Wim Fias
BACKGROUND: Working memory (WM) problems are commonly observed in Alzheimer's disease (AD), but the affected mechanisms leading to impaired WM are still insufficiently understood. The ability to efficiently process serial order in WM has been demonstrated to be fundamental to fluent daily life functioning. The decreased capability to mentally process serial position in WM has been put forward as the underlying explanation for generally compromised WM performance. OBJECTIVE: Determine which mechanisms, such as order processing, are responsible for deficient WM functioning in AD...
July 17, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28730936/an-industry-update-what-is-the-latest-news-in-therapeutic-delivery
#14
Iain Simpson
This Industry Update covers the period from 1 through 30 April 2017, and is based on information sourced from company press releases, scientific literature, patents and various news websites. Biogen expanded its portfolio of developmental drugs targeting neurological diseases by licensing a drug from Bristol-Myers Squibb which is currently under investigation for the treatment of progressive supranuclear palsy. Takeda announced a deal with NuBiyota focused on developing treatments for gastrointestinal disorders, based on the manipulation of microbes living in the gut...
July 2017: Therapeutic Delivery
https://www.readbyqxmd.com/read/28729828/working-memory-profiles-in-hiv-exposed-uninfected-and-hiv-infected-children-a-comparison-with-neurotypical-controls
#15
Robyn Milligan, Kate Cockcroft
This study compared the working memory profiles of three groups of children, namely HIV-infected (HIV-I; n = 95), HIV-exposed, uninfected (HIV-EU; n = 86) and an HIV-unexposed, uninfected, (HIV-UU; n = 92) neurotypical control group. Working memory, an executive function, plays an important role in frontal lobe-controlled behaviors, such as motivation, planning, decision making, and social interaction, and is a strong predictor of academic success in school children. Memory impairments have been identified in HIV-I children, particularly in visuospatial processing...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28729309/the-role-of-a-decision-support-smartphone-application-in-enhancing-community-health-volunteers-effectiveness-to-improve-maternal-and-newborn-outcomes-in-nairobi-kenya-quasi-experimental-research-protocol
#16
Pauline Bakibinga, Eva Kamande, Milka Omuya, Abdhalah K Ziraba, Catherine Kyobutungi
INTRODUCTION: Improving maternal and newborn survival remains major aspirations for many countries in the Global South. Slum settlements, a result of rapid urbanisation in many developing countries including Kenya, exhibit high levels of maternal and neonatal mortality. There are limited referral mechanisms for sick neonates and their mothers from the community to healthcare facilities with ability to provide adequate care. In this study, we specifically plan to develop and assess the added value of having community health volunteers (CHVs) use smartphones to identify and track mothers and children in a bid to reduce pregnancy-related complications and newborn deaths in the urban slums of Kamukunji subcounty in Nairobi, Kenya...
July 20, 2017: BMJ Open
https://www.readbyqxmd.com/read/28729138/spatial-working-memory-in-the-touchscreen-operant-platform-is-disrupted-in-female-rats-by-ovariectomy-but-not-estrous-cycle
#17
Alyssa M Sbisa, Andrea Gogos, Maarten van den Buuse
Learning and memory deficits have been described in rats and mice after ovariectomy (OVX) and across the estrous cycle. Preclinical researchers therefore often avoid using female animals and, consequently, a large male bias exists in the preclinical cognitive literature. In the present study we examined the role of sex hormones in the touchscreen operant platform using the spatial working memory trial unique nonmatching-to-location (TUNL) task. Twenty-nine Long Evans rats were trained to acquire the TUNL task including three incremental spatial separations (S0, S1, S2)...
July 17, 2017: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/28729128/rosettes-engrailed-edges-and-star-shaped-patterns-between-rediscovery-and-forgetfulness-in-the-early-accounts-of-vibrating-liquid-drops-floating-over-hot-surfaces
#18
Seán M Stewart
Small drops of liquid brought into contact with very hot surfaces float above it as beautiful, slightly flattened spheroids without coming to the boil. An example of film boiling, drops that are sessile can often suddenly and quite unexpectedly start to oscillate forming highly symmetric patterns of surprising pulchritude. The rim of these oscillating drops take on "star-shaped" patterns with many different modes of vibration possible. Still an object of study today, their discovery, early accounts, rediscovery and ensuing controversies over claims of priority, before quietly slipping away from the collective memory of the scientific community to become all but forgotten makes for a compelling story in the early history of film boiling...
July 17, 2017: Endeavour
https://www.readbyqxmd.com/read/28728964/association-between-proton-pump-inhibitor-use-and-cognitive-function-in-women
#19
Paul Lochhead, Kaitlin Hagan, Amit D Joshi, Hamed Khalili, Long H Nguyen, Francine Grodstein, Andrew T Chan
BACKGROUND & AIMS: Studies have reported associations between proton pump inhibitor (PPI) use and dementia. However, data are lacking on long-term PPI use and cognitive function. We therefore examined associations between PPI use and performance in tests of cognitive function. Because of shared clinical indications, we examined associations for H2 receptor antagonists (H2RAs) as a secondary aim. METHODS: We used prospectively collected data on medication use and other potential risk factors from 13,864 participants in the Nurses' Health Study II who had completed a self-administered computerized neuropsychological test battery...
July 17, 2017: Gastroenterology
https://www.readbyqxmd.com/read/28727794/lie-construction-affects-information-storage-under-high-memory-load-condition
#20
Yuqiu Liu, Chunjie Wang, Haibo Jiang, Hongjian He, Feiyan Chen
Previous studies indicate that lying consumes cognitive resources, especially working memory (WM) resources. Considering the dual functions that WM might play in lying: holding the truth-related information and turning the truth into lies, the present study examined the relationship between the information storage and processing in the lie construction. To achieve that goal, a deception task based on the old/new recognition paradigm was designed, which could manipulate two levels of WM load (low-load task using 4 items and high-load task using 6 items) during the deception process...
2017: PloS One
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