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https://www.readbyqxmd.com/read/29915651/posterior-reversible-encephalopathy-syndrome-pres-after-bevacizumab-therapy-for-metastatic-colorectal-cancer
#1
Mohsin Hamid, Ali Ghani, Ida Micaily, Usman Sarwar, Bilal Lashari, Faizan Malik
Posterior reversible encephalopathy syndrome (PRES) is an increasingly recognizable neuro-clinical syndrome. Clinical and neurological manifestations of PRES include hypertension, headache, encephalopathy, seizures, and symmetrical white matter changes on brain MRI. Most common precipitants of PRES are acute medical illness, hypertensive crisis, eclampsia, immunosuppressive therapy, and chemotherapy. Bevacizumab is a monoclonal antibody that halts angiogenesis by inhibiting vascular endothelial growth factor...
2018: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/29899785/association-between-posterior-reversible-encephalopathy-syndrome-and-mycoplasma-pneumoniae-infection
#2
Archana Ramgopal, Aravind Thavamani, Abdulla Ghori
Mycoplasma pneumoniae is a microbe known to affect numerous organ systems, and in particular, can cause neurological manifestations. We describe an otherwise healthy child who presented with acute onset intractable headache with magnetic resonance imaging (MRI) findings consistent with posterior reversible encephalopathy syndrome (PRES), a neurological manifestation that presents with headache, vision changes, altered mental status, or seizures. Our patient did not have any of the common etiologies for PRES reported but tested positive for acute M...
January 2018: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/29889274/posterior-reversible-encephalopathy-syndrome-as-a-complication-of-induced-hypertension-in-subarachnoid-hemorrhage-a-case-control-study
#3
Michelle L Allen, Tobias Kulik, Salah G Keyrouz, Rajat Dhar
BACKGROUND: Induced hypertension (IH) remains the mainstay of medical management for delayed cerebral ischemia (DCI) after subarachnoid hemorrhage (SAH). However, raising blood pressure above normal levels may be associated with systemic and neurological complications, of which posterior reversible encephalopathy syndrome (PRES) has been increasingly recognized. OBJECTIVE: To ascertain the frequency and predisposing factors for PRES during IH therapy. METHODS: We identified 68 patients treated with IH from 345 SAH patients over a 3-yr period...
June 8, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29880411/posterior-reversible-encephalopathy-syndrome-in-a-pregnant-patient-without-eclampsia-or-preeclampsia-a-case-report
#4
Hüseyin Acar, Kadriye Acar
Posterior Reversible Encephalopathy syndrome (PRES) is a rare neurologic disorder characterised by vasogenic edema in occipital and parietal lobes on MR. Patients usually complain about headache, visual disturbance, seizure and altered mental status. We repot a case of PRES seen in a pregnant patient. Although pre-eclampsia and eclampsia are among the common causes of this syndrome in this case patient was normotensive and no proteinuria was present. To our knowledge this is the first PRES case presented of a pregnant patient without eclampsia or pre-eclampsia...
May 30, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29877278/nocturnal-hypertension-in-multiple-system-atrophy-may-cause-posterior-reversible-encephalopathy-syndrome
#5
Kaoru Yagita, Kazuto Tsukita, Akiyo Shinde, Toshihiko Suenaga
Nocturnal hypertension (NH) is a symptom of cardiovascular dysautonomia in multiple system atrophy (MSA); however, care and medication are often insufficient. We herein report a patient with MSA who showed posterior reversible encephalopathy syndrome (PRES) caused by hypertension during sleep. He presented clinically with total blindness; T2-weighted magnetic resonance imaging showed high signal intensities in the bilateral subcortical occipital-temporal lobes. His PRES was completely reversed by blood pressure control...
June 6, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29875859/posterior-reversible-encephalopathy-syndrome-as-a-postpartum-complication
#6
Samra Kadić-Vukas, Mirsada Hodžić, Lejla Tandir-Lihić, Lejla Hrvat, Azra Kožo-Kajmaković, Nina Kuzmanović, Haris Vukas
BACKGROUND: Posterior reversible encephalopathy syndrome (PRES) is a clinical-radiological syndrome with seizures, altered consciousness, visual disturbances and headache among other symptoms. Hinchey et al. first described Pres in 1996, with two other case series published shortly after. CASE REPORT: A 23-year-old women patient was emergency sent from General Hospital Tešanj due to a crisis of consciousness and repeated epileptic seizures. The patient had a second birth before 10 days (postpartum cesarean) in general endotracheal anaesthesia (two cesarean-born babies)...
May 20, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29870651/posterior-reversible-encephalopathy-syndrome-as-an-initial-manifestation-of-systemic-lupus-erythematosus
#7
Özözen Zeynep Ayas, Ruhsen Öncel Öcal, Aslı Aksoy Gundogdu
Posterior reversible encephalopathy syndrome (PRES) is a disorder which is diagnosed with its characteristic clinical and radiological findings, typically resolves with treatment. The prevalence of PRES in systemic lupus erythematosus (SLE) patients is not exactly known. A systemic disorder frequently appears as a presenting symptom in SLE. However, in rare cases, the disease starts with a neurological manifestation. Here we report a 35-year-old woman presenting with a headache and blurred vision. She had neurologic symptoms and cerebral lesions on magnetic resonance imaging (MRI) suggesting PRES...
November 30, 2017: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29864559/posterior-reversible-encephalopathy-syndrome-with-status-epilepticus-following-surgery-for-lumbar-stenosis-and-spondylolisthesis-case-report
#8
Pedro David Delgado-López, Gloria Garcés-Pérez, Juan García-Carrasco, Esther Alonso-García, Ana Isabel Gómez-Menéndez, Javier Martín-Alonso
BACKGROUND: Posterior reversible encephalopathy syndrome (PRES) is a clinicoradiological condition encountered in many different clinical settings, generally occurring in the context of hypertensive crisis, immunosuppressive therapy or autoimmune diseases. It is characterized by headache, stupor, seizures and visual alterations. MRI findings include white matter changes preferentially in the parieto-occipital regions. Although pathogenesis is not fully elucidated, vasoconstriction and brain hypoperfusion seem to be the cause of brain ischemia and vasogenic edema...
June 1, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29849324/an-unusual-case-of-posterior-reversible-encephalopathy-syndrome
#9
Robert P Zemple, Tomer Pelleg, Moises R Cossio
A 21-year-old pregnant female with no significant past medical history presented with acute onset headache and nausea as well as tonic-clonic seizures, then rapidly decompensated into a coma with complete absence of brainstem reflexes. The patient was ultimately diagnosed with hemolysis, elevated liver enzymes, and low platelets (HELLP syndrome) and subsequent posterior reversible encephalopathy syndrome (PRES) with brainstem involvement. Emergent delivery and blood pressure control resulted in rapid and complete neurologic recovery...
August 2017: Clinical practice and cases in emergency medicine
https://www.readbyqxmd.com/read/29849301/posterior-reversible-encephalopathy-syndrome-presenting-as-stroke-mimic
#10
Daniel Frick, Martin Huecker, Hugh Shoff
We present the case of a 33-year-old male with end stage renal disease presenting to the emergency department (ED) with headache, dizziness, and unilateral weakness. Initial concern was for ischemic or hemorrhagic stroke. Magnetic resonance imaging confirmed posterior reversible encephalopathy syndrome (PRES). The patient was treated appropriately and made a full neurologic recovery. PRES is an under-recognized diagnosis in the ED. As a stroke mimic, PRES can lead the clinician on an incorrect diagnostic pathway with potential for iatrogenic harm...
August 2017: Clinical practice and cases in emergency medicine
https://www.readbyqxmd.com/read/29797465/concomitant-acute-toxic-leukoencephalopathy-and-posterior-reversible-encephalopathy-syndrome
#11
Can Özütemiz, Sarah Khanipour Roshan, Neil Joseph Kroll, Jeffrey B Rykken, Frederick Ott, Alexander M McKinney
BACKGROUND AND PURPOSE: Posterior reversible encephalopathy syndrome (PRES) and acute toxic leukoencephalopathy (ATL) are both potentially reversible clinicoradiologic entities. Although their magnetic resonance imaging (MRI) findings differ, rarely both may occur simultaneously in acutely encephalopathic patients. Our aim was to determine the incidence and causes of concomitant "ATL-PRES." METHODS: Retrospective search of suspected acutely encephalopathic adults since 1998 throughout our picture archiving and communication system revealed 167 patients with PRES and 106 patients with ATL...
May 24, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29796585/posterior-reversible-leukoencephalopathy-syndrome-pres-after-kidney-transplantation-a-case-report
#12
Carla Beatriz Davi, Bruna Pinheiro de Moraes, Bruno Fontes Lichtenfels, João Batista Saldanha de Castro Filho, Marcelle Maria Portal, Rosangela Munhoz Montenegro, Roberto Ceratti Manfro
INTRODUCTION: Posterior reversible leukoencephalopathy syndrome (PRES) was first described by Hinchey in 1996. The syndrome is characterized by altered level of consciousness, headache, visual changes, and seizures associated with a vasogenic edema of the white matter that occurs predominantly in the occipital and parietal lobes. Imaging tests such as computed tomography (CT) and especially magnetic resonance imaging (MRI) support the diagnosis. CASE REPORT: We report a case of a 48-year-old female patient who underwent a deceased donor kidney transplant and received tacrolimus as a part of the immunosuppressive regimen...
January 2018: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
https://www.readbyqxmd.com/read/29790335/accurate-electron-nucleus-distances-from-paramagnetic-relaxation-enhancements
#13
Henry W Orton, Gottfried Otting
Measurements of paramagnetic relaxation enhancements (PRE) in 1H-NMR spectra are an important tool to obtain long-range distance information in proteins, but quantitative interpretation is easily compromised by non-specific intermolecular PREs. Here we show that PREs generated by lanthanides with anisotropic magnetic susceptibilities offer a route to accurate calibration-free distance measurements. As these lanthanides change 1H chemical shifts due to pseudocontact shifts, the relaxation rates in the paramagnetic and diamagnetic state can be measured with a single sample that simultaneously contains the protein labeled with a paramagnetic and a diamagnetic lanthanide ion...
May 23, 2018: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29773274/scleroderma-in-children
#14
REVIEW
Francesco Zulian
Juvenile scleroderma with its two varieties, juvenile localized scleroderma and systemic sclerosis (SSc), represents the third most frequent rheumatic disease in childhood. In juvenile SSc, new developments have been recently reported in the fields of classification and monitoring. The introduction of new classification criteria for adult SSc has stimulated new ideas on how to improve the performance of the provisional 2007 PRES/ACR/EULAR pediatric criteria. The introduction of a multidimensional severity score, named "J4S," which includes parameters on growth, skin, and internal organ involvement, has improved the approach to the patients in the daily practice to guide decision-making...
August 2017: Best Practice & Research. Clinical Rheumatology
https://www.readbyqxmd.com/read/29758393/phase-i-trial-of-brentuximab-vedotin-for-steroid-refractory-chronic-graft-versus-host-disease-after-allogeneic-hematopoietic-cell-transplantation
#15
Zachariah DeFilipp, Shuli Li, Maria E Kempner, Jami Brown, Candice Del Rio, Betsy Valles, Chrisa Hunnewell, Meredith Saylor, Julie Vanderklish, Bimalangshu R Dey, Areej El-Jawahri, Steven L McAfee, Thomas R Spitzer, Yi-Bin Chen
We conducted a phase I study of brentuximab vedotin (BV), an antibody-drug conjugate targeting CD30, for the treatment of steroid-refractory chronic graft-versus-host disease (cGVHD). A modified 3 + 3 study design was used with the primary endpoint to determine the maximum tolerated dose of BV in this population. Escalating doses of BV were planned, starting with .6 mg/kg every 3 weeks (dose level 0) and increasing by .3 mg/kg per dose level. BV was administered in 21-day cycles for up to 16 cycles of therapy...
May 24, 2018: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/29748340/correction-eular-pres-standards-and-recommendations-for-the-transitional-care-of-young-people-with-juvenile-onset-rheumatic-diseases
#16
(no author information available yet)
No abstract text is available yet for this article.
June 2018: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29748058/unusual-aspect-of-posterior-reversible-encephalopathy-syndrome-in-an-elderly-adult
#17
Benjamin Hebant, Omar Bennani
BACKGROUND: Posterior reversible encephalopathy syndrome (PRES) classically occurs in patients presenting with a sudden increase of arterial pressure or eclampsia, but the range of etiologies is very wide. Although the mechanisms underlying PRES remain unclear, research suggests that when the extent of hypertension exceeds the threshold of cerebral blood flow autoregulation, this induces blood-brain barrier disruption that leads to brain edema. Unusual presentations on magnetic resonance imaging (MRI) are possible, including the involvement of frontal or temporal lobes, cerebellar hemispheres, basal ganglia, brainstem, or deep white matter...
May 7, 2018: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29738026/posterior-reversible-leukoencephalopathy-syndrome-pres-after-kidney-transplantation-a-case-report
#18
Carla Beatriz Davi, Bruna Pinheiro de Moraes, Bruno Fontes Lichtenfels, João Batista Saldanha de Castro Filho, Marcelle Maria Portal, Rosangela Munhoz Montenegro, Roberto Ceratti Manfro
INTRODUCTION: Posterior reversible leukoencephalopathy syndrome (PRES) was first described by Hinchey in 1996. The syndrome is characterized by altered level of consciousness, headache, visual changes, and seizures associated with a vasogenic edema of the white matter that occurs predominantly in the occipital and parietal lobes. Imaging tests such as computed tomography (CT) and especially magnetic resonance imaging (MRI) support the diagnosis. CASE REPORT: We report a case of a 48-year-old female patient who underwent a deceased donor kidney transplant and received tacrolimus as a part of the immunosuppressive regimen...
April 19, 2018: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
https://www.readbyqxmd.com/read/29737823/rehabilitation-nutrition-in-pressure-ulcer-management-with-type-2-diabetes-a-case-report
#19
Yoko Saino, Hidetaka Wakabayashi, Keisuke Maeda, Shinta Nishioka, Takako Hao, Kenji Mimatsu
BACKGROUND AND OBJECTIVES: Severe infection, inadequate food intake, and pressure ulcers in patients with type 2 diabetes can result in malnutrition. We describe a case in which rehabilitation nutrition was effective for treat-ing a pressure ulcer in a malnourished patient with type 2 diabetes. METHODS AND RESULTS: A 58-year-old man with type 2 diabetes was diagnosed with hidradenitis suppurativa on the left buttock and thigh and a severe pres-sure ulcer on his left kneecap...
2018: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29728839/development-of-minimum-standards-of-care-for-juvenile-localized-scleroderma
#20
REVIEW
Tamás Constantin, Ivan Foeldvari, Clare E Pain, Annamária Pálinkás, Peter Höger, Monika Moll, Dana Nemkova, Lisa Weibel, Melinda Laczkovszki, Philip Clements, Kathryn S Torok
Juvenile localized scleroderma (jLS), also known as morphea, is an orphan disease. Pediatric guidelines regarding diagnosis, assessment, and management are lacking.Our objective was to develop minimum standards of care for diagnosis, assessment, and management of jLS. A systematic review was undertaken to establish the pediatric evidence for assessment and monitoring of jLS. An expert panel, including members of the Pediatric Rheumatology European Society (PRES) Scleroderma Working Group, were invited to a consensus meeting where recommendations were developed based on evidence graded by the systematic review and, where evidence was lacking, consensus opinion...
May 4, 2018: European Journal of Pediatrics
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