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https://www.readbyqxmd.com/read/29773510/implications-of-the-abcd-study-for-developmental-neuroscience
#1
Sarah W Feldstein Ewing, James M Bjork, Monica Luciana
The Adolescent Brain Cognitive Development Study (ABCD) will capture a breadth of multi-faceted biobehavioral, environmental, familial, and genetic longitudinal developmental open-access data from over 11,000 9-10 year olds throughout the United States of America (USA) for an envisioned ten-year span. This will subsequently represent the largest study ever attempted with this level of brain phenotypic detail. This study holds the opportunity for exciting advances in the understanding of typical adolescent neurodevelopment, discovery of neurodevelopmental underpinnings of mental illness, as well as the neurodevelopmental influences of (and on) social factors, substance use, and critically - their interaction...
May 14, 2018: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/29773251/-abcde-a-new-approach-to-patient-management-in-emergency-departments
#2
Frédéric Lodier
The ABCDE method constitutes an effective method of patient management in an emergency department. It is structured, systematic and universal. Many patients are able to benefit from it, in traumatology as well as in other sectors. It requires specific training.
May 2018: Soins; la Revue de Référence Infirmière
https://www.readbyqxmd.com/read/29748734/selection-of-bypass-vs-sleeve-for-the-management-of-type-2-diabetes-in-severely-obese-could-ethnicity-play-a-role
#3
Aparna Govil Bhasker, John B Dixon, Muffazal Lakdawala
PURPOSE: Prospective data was evaluated to see whether bariatric procedure type made any difference to diabetes remission. METHODS: One hundred eighty-six consecutive patients of Indian ethnicity (M:F 89:97) with type 2 diabetes mellitus (T2DM) and HbA1c > 6.5 were assessed before and at 1 year following surgery. Age, BMI, C-peptide and duration of diabetes (ABCD - described by WJ Lee), insulin use, baseline HbA1c, and % weight loss were tested as modifiers...
May 10, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29740896/gold-assessment-of-copd-severity-in-the-clinical-practice-research-datalink-cprd
#4
Cristina Rebordosa, Estel Plana, Jaume Aguado, Steven Thomas, Esther García-Gil, Susana Perez-Gutthann, Jordi Castellsague
PURPOSE: To evaluate availability of spirometry and symptom data in the Clinical Practice Research Datalink (United Kingdom) to assess COPD severity using the Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2016 definition and comparing it with an algorithm used in other studies. METHODS: This was a descriptive, noninterventional, secondary database cohort study of patients with COPD aged 40 years or older, who initiated treatment with specific COPD medications...
May 8, 2018: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/29736250/mikc-c-type-mads-box-genes-in-rosa-chinensis-the-remarkable-expansion-of-abcde-model-genes-and-their-roles-in-floral-organogenesis
#5
Jinyi Liu, Xiaodong Fu, Yuwei Dong, Jun Lu, Min Ren, Ningning Zhou, Changquan Wang
MIKCC -type MADS-box (MIKCC ) genes encode transcription factors that have crucial roles in controlling floral organogenesis and flowering time in plants. Although this gene family has been well characterized in many plant species, its evolutionary and comprehensive functional analysis in rose is lacking. In this study, 58 non-redundant MIKCC uni-transcripts were extensively identified from rose transcriptomes. Phylogenetic analysis placed these genes into 12 clades with their Arabidopsis and strawberry counterparts, and revealed that ABCDE model (including AP1/FUL, AP3/PI, AG, and SEP clades), and SOC1 and AGL6 clade genes have remarkably expanded in Rosa chinensis , whereas genes from the FLC and AGL17 clades were undetectable...
2018: Horticulture Research
https://www.readbyqxmd.com/read/29733608/stereocontrolled-construction-of-abcd-tetracyclic-ring-system-with-vicinal-all-carbon-quaternary-stereogenic-centers-of-calyciphylline-a-type-alkaloids
#6
Yusuke Sasano, Junpei Koyama, Kaori Yoshikawa, Naoki Kanoh, Eunsang Kwon, Yoshiharu Iwabuchi
A unique approach to the synthesis of an ABCD tetracyclic core bearing the vicinal all-carbon quaternary stereogenic centers of the calyciphylline A type alkaloids is reported. The synthesis features two C-C bond formations at a sterically congested position: one is an intramolecular pinacol coupling to construct the central A ring; the other is a semipinacol rearrangement to construct a quaternary stereogenic center adjacent to another quaternary center.
May 7, 2018: Organic Letters
https://www.readbyqxmd.com/read/29706313/a-description-of-the-abcd-organizational-structure-and-communication-framework
#7
REVIEW
Allison M Auchter, Margie Hernandez Mejia, Charles J Heyser, Paul D Shilling, Terry L Jernigan, Sandra A Brown, Susan F Tapert, Gayathri J Dowling
The Adolescent Brain Cognitive Development (ABCD) study is designed to be the largest study of brain development and child health in the United States, performing comprehensive assessments of 11,500 children repeatedly for 10 years. An endeavor of this magnitude requires an organized framework of governance and communication that promotes collaborative decision-making and dissemination of information. The ABCD consortium structure, built upon the Matrix Management approach of organizational theory, facilitates the integration of input from all institutions, numerous internal workgroups and committees, federal partners, and external advisory groups to make use of a broad range of expertise to ensure the study's success...
April 16, 2018: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/29703560/recruiting-the-abcd-sample-design-considerations-and-procedures
#8
H Garavan, H Bartsch, K Conway, A Decastro, R Z Goldstein, S Heeringa, T Jernigan, A Potter, W Thompson, D Zahs
The ABCD study is a new and ongoing project of very substantial size and scale involving 21 data acquisition sites. It aims to recruit 11,500 children and follow them for ten years with extensive assessments at multiple timepoints. To deliver on its potential to adequately describe adolescent development, it is essential that it adopt recruitment procedures that are efficient and effective and will yield a sample that reflects the nation's diversity in an epidemiologically informed manner. Here, we describe the sampling plans and recruitment procedures of this study...
April 16, 2018: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/29702452/decision-making-performance-of-depressed-patients-within-72-h-following-a-suicide-attempt
#9
Klára M Hegedűs, Andrea Szkaliczki, Bernadett I Gál, Bálint Andó, Zoltán Janka, Péter Z Álmos
BACKGROUND: The significance of decision-making in suicidal behaviour is often highlighted; however, the performance of persons in suicide crisis is unknown. This study aimed to explore the comprehensive decision-making profile of depressed patients following a suicide attempt. METHODS: Decision-making was measured by reward- ("ABCD") and punishment- ("EFGH") sensitive versions of the Iowa Gambling Task (IGT) in 59 medication-free depressed patients within 72 h after a suicide attempt and in 46 healthy control subjects...
April 16, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29698993/evolution-of-keratoconus-from-diagnosis-to-therapeutics
#10
Lauren Marie Imbornoni, Charles Ninian John McGhee, Michael Wellington Belin
This review describes the evolution of the diagnosis and treatment of keratoconus from the earliest written description to present day. The first description was provided in 1736 by Benedict Duddell who described the prominent corneas of a fourteen-year-old boy. Throughout the 19th century, a variety of surgical procedures were proposed to manage the disease, such as surgically repositioning the pupil away from the cone, iris incarceration to produce a slit-like pupil, cauterization of the cone to produce a scar, and full thickness elliptical excision of the cone...
April 26, 2018: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/29692385/changes-in-global-initiative-for-chronic-obstructive-lung-disease-abcd-groups-and-the-impact-of-regrouping-on-treatment-a-comparison-of-2017-and-2014
#11
Ya-Nan Cui, Ping Chen, Zhong-Shang Dai, Yan Chen
No abstract text is available yet for this article.
May 5, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29680211/outreach-and-innovation-communication-strategies-for-the-abcd-study
#12
Elizabeth A Hoffman, Katia D Howlett, Florence Breslin, Gayathri J Dowling
The Adolescent Brain Cognitive Development (ABCD) Study, a large, longitudinal study of brain development and child health, relies on the engagement of communities, educators, and families to ensure its success. To that end, community and partner relationships, development of targeted messages and materials for specific audiences (educators, families, youth, scientists), and continued and consistent outreach must be an integral part of the Consortium activities. The ABCD Consortium has made these efforts a priority and developed a framework to raise awareness about the study and promote sustained broad-base support from diverse stakeholders...
April 16, 2018: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/29673337/communities-in-charge-of-alcohol-cica-a-protocol-for-a-stepped-wedge-randomised-control-trial-of-an-alcohol-health-champions-programme
#13
Penny A Cook, Suzy C Hargreaves, Elizabeth J Burns, Frank de Vocht, Steve Parrott, Margaret Coffey, Suzanne Audrey, Cathy Ure, Paul Duffy, David Ottiwell, Kiran Kenth, Susan Hare, Kate Ardern
BACKGROUND: Communities In Charge of Alcohol (CICA) takes an Asset Based Community Development (ABCD) approach to reducing alcohol harm. Through a cascade training model, supported by a designated local co-ordinator, local volunteers are trained to become accredited 'Alcohol Health Champions' to provide brief opportunistic advice at an individual level and mobilise action on alcohol availability at a community level. The CICA programme is the first time that a devolved UK region has attempted to coordinate an approach to building health champion capacity, presenting an opportunity to investigate its implementation and impact at scale...
April 19, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29655614/a-brief-validated-screen-to-identify-boys-and-girls-at-risk-for-early-marijuana-use
#14
Rolf Loeber, Duncan B Clark, Lia Ahonen, Douglas FitzGerald, Elisa M Trucco, Robert A Zucker
To guide recruitment, the ABCD Study requires a method for identifying children at high risk for early-onset substance use that may be utilized during the recruitment process. This study was undertaken to inform the development of a brief screen for identifying youths' risk of early-onset substance use and other adverse outcomes. To be acceptable by participants in this context, consideration of potential items was limited to child characteristics previously determined to be potentially pertinent and parental cigarette smoking...
April 7, 2018: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/29642694/integrated-quadruple-stress-echocardiography
#15
Eugenio Picano, Doralisa Morrone, Maria C Scali, Alda Huqi, Katia Coviello, Quirino Ciampi
Stress Echocardiography (SE) is an established diagnostic technique. For 40 years, the cornerstone of the technique has been the detection of regional wall motion abnormalities (RWMA), due to the underlying physiologically-relevant epicardial coronary artery stenosis. In the last decade, three new parameters (more objective than RWMA) have shown the potential to integrate and comple- ment RWMA: 1- B-lines, also known as ultrasound lung comets, as a marker of extra-vascular lung water, measured using lung ultrasound with the 4-site simplified scan symmetrically of the antero- lateral thorax on the third intercostal space, from mid-axillary to anterior axillary and mid- clavicular line; 2-left ventricular contractile reserve (LVCR), assessed as the peak stress/rest ratio of left ventricular force, also known as elastance (systolic arterial pressure by cuff sphygmomanome- ter/end-systolic volume from 2D echocardiography); 3- coronary flow velocity reserve (CFVR) on left anterior descending coronary artery, calculated as peak stress/rest ratio of diastolic peak flow velocity assessed using pulsed-wave Doppler...
April 11, 2018: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/29627333/assessment-of-culture-and-environment-in-the-adolescent-brain-and-cognitive-development-study-rationale-description-of-measures-and-early-data
#16
REVIEW
Robert A Zucker, Raul Gonzalez, Sarah W Feldstein Ewing, Martin P Paulus, Judith Arroyo, Andrew Fuligni, Amanda Sheffield Morris, Mariana Sanchez, Thomas Wills
Neurodevelopmental maturation takes place in a social environment in addition to a neurobiological one. Characterization of social environmental factors that influence this process is therefore an essential component in developing an accurate model of adolescent brain and neurocognitive development, as well as susceptibility to change with the use of marijuana and other drugs. The creation of the Culture and Environment (CE) measurement component of the ABCD protocol was guided by this understanding. Three areas were identified by the CE Work Group as central to this process: influences relating to CE Group membership, influences created by the proximal social environment, influences stemming from social interactions...
March 17, 2018: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/29606560/biospecimens-and-the-abcd-study-rationale-methods-of-collection-measurement-and-early-data
#17
REVIEW
Kristina A Uban, Megan K Horton, Joanna Jacobus, Charles Heyser, Wesley K Thompson, Susan F Tapert, Pamela A F Madden, Elizabeth R Sowell
Biospecimen collection in the Adolescent Brain Cognitive Development (ABCD) study - of hair samples, shed deciduous (baby) teeth, and body fluids - will serve dual functions of screening for study eligibility, and providing measures of biological processes thought to predict or correlate with key study outcomes on brain and cognitive development. Biosamples are being collected annually to screen for recency of drug use prior to the neuroimaging or cognitive testing visit, and to store for the following future studies: (1) on the effects of exposure to illicit and recreational drugs (including alcohol and nicotine); (2) of pubertal hormones on brain and cognitive developmental trajectories; (3) on the contribution of genomics and epigenomics to child and adolescent development and behavioral outcomes; and (4) with pre- and post-natal exposure to environmental neurotoxicants and drugs of abuse measured from novel tooth analyses...
March 16, 2018: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/29601502/demographics-and-psychological-factors-associated-with-adiposity-in-nurses
#18
Bernarda Sánchez-Jiménez, Reyna Sámano, Daniela Chinchilla-Ochoa, Rosa Morales-Hernández, Ana Rodríguez-Ventura
Adiposity-based chronic disease (ABCD), overweight-Ow- or obesity-Ob-) in health personnel is as frequent as in the general population, even though they understand well the importance of maintaining a healthy weight. Thus, it is highly likely that certain demographic and psychological conditions, independently of knowledge, are contributing to develop ABCD. The aim of this study was to examine the association between these factors and ABCD in nurses. Data were collected from a cross-sectional study conducted in a tertiary level institute in Mexico City from 2012 to 2013...
March 30, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29577560/prevalence-and-severity-of-nafld-by-transient-elastography-genetic-and-metabolic-risk-factors-in-a-general-population
#19
Salvatore Petta, Vito Di Marco, Rosaria Maria Pipitone, Stefania Grimaudo, Carola Buscemi, Antonio Craxì, Silvio Buscemi
BACKGROUND/AIMS: The worldwide spread of obesity is leading to a dramatic increase in the prevalence of nonalcoholic fatty liver disease (NAFLD) and its complications. We aimed to evaluate both prevalence and factors associated with NAFLD in a general population in a Mediterranean area. METHODS: We considered 890 consecutive individuals included in the community-based ABCD (Alimentazione, Benessere Cardiovascolare e Diabete) study (ISRCTN15840340). Controlled attenuation parameter (CAP) and liver stiffness measurement (LSM) were measured with FibroScan...
March 25, 2018: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/29567376/the-adolescent-brain-cognitive-development-abcd-study-imaging-acquisition-across-21-sites
#20
REVIEW
B J Casey, Tariq Cannonier, May I Conley, Alexandra O Cohen, Deanna M Barch, Mary M Heitzeg, Mary E Soules, Theresa Teslovich, Danielle V Dellarco, Hugh Garavan, Catherine A Orr, Tor D Wager, Marie T Banich, Nicole K Speer, Matthew T Sutherland, Michael C Riedel, Anthony S Dick, James M Bjork, Kathleen M Thomas, Bader Chaarani, Margie H Mejia, Donald J Hagler, M Daniela Cornejo, Chelsea S Sicat, Michael P Harms, Nico U F Dosenbach, Monica Rosenberg, Eric Earl, Hauke Bartsch, Richard Watts, Jonathan R Polimeni, Joshua M Kuperman, Damien A Fair, Anders M Dale
The ABCD study is recruiting and following the brain development and health of over 10,000 9-10 year olds through adolescence. The imaging component of the study was developed by the ABCD Data Analysis and Informatics Center (DAIC) and the ABCD Imaging Acquisition Workgroup. Imaging methods and assessments were selected, optimized and harmonized across all 21 sites to measure brain structure and function relevant to adolescent development and addiction. This article provides an overview of the imaging procedures of the ABCD study, the basis for their selection and preliminary quality assurance and results that provide evidence for the feasibility and age-appropriateness of procedures and generalizability of findings to the existent literature...
March 14, 2018: Developmental Cognitive Neuroscience
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