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https://www.readbyqxmd.com/read/28645657/gross-pathology-physiological-and-toxicological-responses-in-relation-to-metals-and-persistent-organic-pollutants-pops-burden-in-tilapia-species-from-ogun-river-nigeria
#1
Oju R Ibor, Aina O Adeogun, Azubuike V Chukwuka, Augustine Arukwe
We have investigated gross pathology, physiological (steroid precursors) and toxicological responses (oxidative stress and phase II biotransformation) in relation to tissue contaminant burden in Tilapia species along the entire length (320 km) of Ogun River, Nigeria. The Ogun River is the longest and largest river in Southwestern Nigeria located along heavily industrialized cities and receives complex mixtures of effluents. A total of 1074 tilapias were collected from three sampling points (Abeokuta, Isheri and Ikorodu) and from an upstream control point (Igboho) and evaluated for gross pathological changes, hepatic transcript levels for oxidative stress and phase II biotransformation responses...
June 8, 2017: Marine Environmental Research
https://www.readbyqxmd.com/read/28644720/the-effect-of-internal-migration-individual-and-contextual-characteristics-on-contraceptive-use-among-nigeria-women
#2
Joshua O Akinyemi, Clifford O Odimegwu, Ayo S Adebowale
We investigated the relation of internal migration to contraceptive use and adjusted for individual and contextual (community) characteristics. Multilevel logistic regression models were fitted to nationally representative data on 28876 women from 884 communities in Nigeria. Only about 1 out of every 10 women (10.4%) currently used a contraceptive method. Contraceptive prevalence according to migration status were: rural-urban (12.5%), urban-rural (13.8%), rural non-migrants (6.2%) and urban non-migrants (17...
June 23, 2017: Health Care for Women International
https://www.readbyqxmd.com/read/28643746/breast-cancer-screening-practices-amongst-female-tertiary-health-worker-in-nnewi
#3
Chimezie Innocent Madubogwu, Amobi Ochonma Egwuonwu, Ngozi Ukamaka Madubogwu, Ifeoma A Njelita
BACKGROUND: Breast cancer in Nigeria and other developing countries is characterized by late presentation and poor outcome due to ignorance, superstition, self-denial, fear of mastectomy, and unavailability of treatment facilities. The mortality of breast cancer in Western world is decreasing due to early detection and better management. OBJECTIVE: This study aims at accessing the knowledge, attitude, and practice of breast cancer screening among female tertiary health workers...
April 2017: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28642786/signatures-of-selection-for-environmental-adaptation-and-zebu-%C3%A3-taurine-hybrid-fitness-in-east-african-shorthorn-zebu
#4
Hussain Bahbahani, Abdulfatai Tijjani, Christopher Mukasa, David Wragg, Faisal Almathen, Oyekanmi Nash, Gerald N Akpa, Mary Mbole-Kariuki, Sunir Malla, Mark Woolhouse, Tad Sonstegard, Curtis Van Tassell, Martin Blythe, Heather Huson, Olivier Hanotte
The East African Shorthorn Zebu (EASZ) cattle are ancient hybrid between Asian zebu × African taurine cattle preferred by local farmers due to their adaptability to the African environment. The genetic controls of these adaptabilities are not clearly understood yet. Here, we genotyped 92 EASZ samples from Kenya (KEASZ) with more than 770,000 SNPs and sequenced the genome of a pool of 10 KEASZ. We observe an even admixed autosomal zebu × taurine genomic structure in the population. A total of 101 and 165 candidate regions of positive selection, based on genome-wide SNP analyses (meta-SS, Rsb, iHS, and ΔAF) and pooled heterozygosity (Hp) full genome sequence analysis, are identified, in which 35 regions are shared between them...
2017: Frontiers in Genetics
https://www.readbyqxmd.com/read/28642581/molecular-methods-to-detect-spodoptera-frugiperda-in-ghana-and-implications-for-monitoring-the-spread-of-invasive-species-in-developing-countries
#5
Matthew J W Cock, Patrick K Beseh, Alan G Buddie, Giovanni Cafá, Jayne Crozier
Spodoptera frugiperda (J. E. Smith) (Lepidoptera: Noctuidae) is a polyphagous pest indigenous throughout the Americas, which recently appeared in Africa, first reported from São Tomé, Nigeria, Bénin and Togo in 2016, and which we now report from Ghana. This species is recognised to comprise two morphologically identical but genetically distinct strains or species in the Americas, and we found both to be present in Ghana. We discuss possible routes of entry to Africa, of which the likeliest is adults and/or egg masses transported on direct commercial flights between the Americas and West Africa, followed by dispersal by adult flight within Africa...
June 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28642064/the-genetic-basis-of-deafness-in-populations-of-african-descent
#6
REVIEW
Jason R Rudman, Rosemary I Kabahuma, Sara E Bressler, Yong Feng, Susan H Blanton, Denise Yan, Xue-Zhong Liu
Hearing loss is the most common sensorineural disorder worldwide and is associated with more than 1000 mutations in more than 90 genes. While mutations in genes such as GJB2 (gap-junction protein β 2) and GJB6 (gap-junction protein β 6) are highly prevalent in Caucasian, Asian, and Middle Eastern populations, they are rare in both native African populations and those of African descent. The objective of this paper is to review the current knowledge regarding the epidemiology and genetics of hearing loss in African populations with a focus on native sub-Saharan African populations...
May 6, 2017: Journal of Genetics and Genomics, Yi Chuan Xue Bao
https://www.readbyqxmd.com/read/28641026/sociodemographic-factors-associated-with-female-genital-cutting-among-women-of-reproductive-age-in-nigeria
#7
T O Ojo, M Y Ijadunola
OBJECTIVES: The aims of the study were to determine the prevalence of female genital cutting (FGC) among women of reproductive age in Nigeria and identify the sociodemographic factors associated with the practice. METHODS: A secondary analysis of the 2013 Nigeria Demographic and Health Survey was carried out in 38,948 women of reproductive age (15-49 years). RESULTS: The prevalence of FGC among respondents was almost 25%, most of whom (82%) had undergone the procedure when they were under 5 years of age...
June 22, 2017: European Journal of Contraception & Reproductive Health Care
https://www.readbyqxmd.com/read/28640809/development-of-elisas-for-diagnosis-of-acute-typhoid-fever-in-nigerian-children
#8
Jiin Felgner, Aarti Jain, Rie Nakajima, Li Liang, Algis Jasinskas, Eduardo Gotuzzo, Joseph M Vinetz, Fabio Miyajima, Munir Pirmohamed, Fatimah Hassan-Hanga, Dominic Umoru, Binta Wudil Jibir, Safiya Gambo, Kudirat Olateju, Philip L Felgner, Stephen Obaro, D Huw Davies
Improved serodiagnostic tests for typhoid fever (TF) are needed for surveillance, to facilitate patient management, curb antibiotic resistance, and inform public health programs. To address this need, IgA, IgM and IgG ELISAs using Salmonella enterica serovar Typhi (S. Typhi) lipopolysaccharide (LPS) and hemolysin E (t1477) protein were conducted on 86 Nigerian pediatric TF and 29 non-typhoidal Salmonella (NTS) cases, 178 culture-negative febrile cases, 28 "other" (i.e., non-Salmonella) pediatric infections, and 48 healthy Nigerian children...
June 22, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28640795/progress-toward-containment-of-poliovirus-type-2-worldwide-2017
#9
Nicoletta Previsani, Harpal Singh, Jeanette St Pierre, Liliane Boualam, Jacqueline Fournier-Caruana, Roland W Sutter, Michel Zaffran
The Global Polio Eradication Initiative (GPEI) continues to make progress toward the eradication target. Only one of the three serotypes, wild poliovirus (WPV) type 1 (WPV1), is still circulating, and the numbers of cases and countries with endemic transmission are at record lows. With the certification of wild poliovirus type 2 (WPV2) eradication in 2015 and the global replacement of trivalent oral poliovirus vaccine (tOPV) containing Sabin poliovirus types 1, 2, and 3 with bivalent OPV containing only Sabin poliovirus types 1 and 3 during April-May 2016, poliovirus type 2 (PV2) is now an eradicated pathogen...
June 23, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28639494/status-of-mental-health-services-for-adolescents-with-psychiatric-morbidity-in-youth-correctional-institutions-in-lagos
#10
Olayinka Atilola, Bolanle Ola, Gbonjubola Abiri, Modepeola Sahid-Adebambo, Olubukayo Odukoya, Abiodun Adewuya, Olurotimi Coker, Oluwadamilola Folarin, Adedolapo Fasawe
BACKGROUND: High prevalence rates of psychiatric morbidity have been documented among adolescents within youth correctional institutions in Nigeria. However, there has not been prior investigation to determine the capacity for and nature of mental health services being provided in these institutions. OBJECTIVES: To assess psychiatric morbidity among adolescents within youth correctional institutions in Lagos, while simultaneously examining the capacity for and the scope of mental health services...
May 2017: Journal of Child and Adolescent Mental Health
https://www.readbyqxmd.com/read/28638553/a-review-of-640-oral-squamous-cell-carcinoma-cases-in-nigeria
#11
Ahmed-Oluwatoyin Lawal, Akinyele-Olumuyiwa Adisa, Olajumoke-Ajibola Effiom
BACKGROUND: Oral squamous cell carcinoma (OSCC) is the most prevalent malignant neoplasm in the oral cavity and accounts for 70% to 90% of all oral malignant neoplasms. The aim of this study was to examine the demographic distribution of OSCC in five Tertiary Health centres in Nigeria. MATERIAL AND METHODS: All cases diagnosed as OSCC during the period from 1970 -2014 were retrieved from the records of five teaching hospitals in Nigeria. Hematoxylin and eosin stained histological slides of all cases that had a diagnosis of OSCC were reviewed for confirmation and inclusion...
June 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28634868/occurrence-removal-and-health-risk-assessment-of-phthalate-esters-in-the-process-streams-of-two-different-wastewater-treatment-plants-in-lagos-and-ogun-states-nigeria
#12
O O Olujimi, O A Aroyeun, T F Akinhanmi, T A Arowolo
Phthalate esters (PEs) are one of the environmentally active organic pollutants capable of causing endocrine disruption. The levels of PE congeners were determined in the influent and effluent from Covenant Oxidation Pond (COP) and Ikeja Wastewater Treatment Plant (IWWTP). Standard methods were adopted for determining the physical and chemical parameters of the water samples. The water samples for PE congener's determination were collected, acidified and stored at 4 °C prior to liquid-liquid extraction and analysis by gas chromatograph...
July 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28634496/household-response-to-inadequate-sewerage-and-garbage-collection-services-in-abuja-nigeria
#13
Ismaila Rimi Abubakar
Provision of sanitation and garbage collection services is an important and yet challenging issue in the rapidly growing cities of developing countries, with significant human health and environmental sustainability implications. Although a growing number of studies have investigated the consequences of inadequate delivery of basic urban services in developing countries, few studies have examined how households cope with the problems. Using the Exit, Voice, Loyalty, and Neglect (EVLN) model, this article explores how households respond to inadequate sewerage and garbage collection services in Abuja, Nigeria...
2017: Journal of Environmental and Public Health
https://www.readbyqxmd.com/read/28629283/prevalence-and-correlates-of-major-depression-among-nigerian-adults-with-sickle-cell-disease
#14
Saheed O Raji, Ambrose O Lawani, Bawo O James
Objective To ascertain the current and lifetime prevalence of depression among adults with sickle cell disease and identify relevant socio-demographic and clinical correlates. Method A cross-sectional study of 205 stable adult out-patient attendees at a treatment center in southern Nigeria between April and September, 2014. A socio-demographic questionnaire, the depression module of Mini International Neuropsychiatric Interview, and the eight-item Morisky Medication Adherence Scale were administered. Categorical and continuous variables associated with a diagnosis of depression were tested using chi-squared and t-tests respectively...
July 2016: International Journal of Psychiatry in Medicine
https://www.readbyqxmd.com/read/28628444/case-of-nigeria-acquired-human-african-trypanosomiasis-in-united-kingdom-2016
#15
Akish Luintel, Patricia Lowe, Anneli Cooper, Annette MacLeod, Philippe Büscher, Tim Brooks, Mike Brown
Human African trypanosomiasis has not been reported in Nigeria since 2012. Nevertheless, limitations of current surveillance programs mean that undetected infections may persist. We report a recent case of stage 2 trypanosomiasis caused by Trypanosoma brucei gambiense acquired in Nigeria and imported into the United Kingdom.
July 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28627939/off-label-prescribing-for-children-with-chronic-diseases-in-nigeria-findings-and-implications
#16
Kazeem Adeola Oshikoya, Ibrahim Adekunle Oreagba, Brian Godman, Joseph Fadare, Samuel Orubu, Amos Massele, Idowu Odunayo Senbanjo
BACKGROUND AND AIMS: Prescribing medicines in an off-label manner for children with chronic conditions is sparsely documented, even more so among developing countries. This needs addressing. The objective was to investigate the extent of this prescribing among children with epilepsy, asthma, and sickle cell anaemia in Nigeria. METHODS: Prescriptions for children ≤16 years documented in their case files that attended paediatric clinics in Lagos, Nigeria, for these three conditions between January and October 2015, were reviewed retrospectively to extract data on the medicines prescribed...
June 19, 2017: Expert Opinion on Drug Safety
https://www.readbyqxmd.com/read/28626853/conjunctival-melanoma-in-southwestern-nigeria-a-case-series-and-review-of-literature
#17
Oluyemi Fasina, Olayiwola A Oluwasola
PURPOSE: Conjunctival melanoma is a rare tumor worldwide and is extremely rare among black population. This study aims to report the demographics, clinical presentation, treatment, and outcome of patients seen in an indigenous black population in Southwestern Nigeria. METHODS: All patients histologically diagnosed with conjunctival melanoma and managed in the facility were reviewed. Their demographics, clinical presentation, treatment received, outcome of treatment, and histopathological features were analyzed...
June 19, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28620974/evaluation-of-the-nigerian-urban-reproductive-health-initiative-nurhi-program
#18
(no author information available yet)
Gaps remain in understanding whether family planning (FP) programs can change urban women's FP behaviors. Even less is known about what works among poor urban women. This article presents results of the impact evaluation of the Nigerian Urban Reproductive Health Initiative (NURHI). Findings are based on recently collected longitudinal data from women and facilities in six cities in Nigeria. Over the four-year follow-up period, there was an increase of about ten percentage points in modern method use. Impact evaluation analyses using fixed-effects regression methods indicate that both demand- and supply-side program activities increased modern method use...
June 16, 2017: Studies in Family Planning
https://www.readbyqxmd.com/read/28619504/kolaviron-shows-anti-proliferative-effect-and-down-regulation-of-vascular-endothelial-growth-factor-c-and-toll-like-receptor-2-in-wuchereria-bancrofti-infected-blood-lymphocytes
#19
Aliyu Muhammad, Audu Funmilola, Idowu A Aimola, Iliya S Ndams, Mairo H Inuwa, Andrew J Nok
The anti-proliferative effect and down regulation of vascular endothelial growth factor C and toll like receptor-2 by kolaviron on Wuchereria bancrofti infected peripheral blood lymphocytes were investigated. Blood were collected from consenting volunteers in Talata Mafara, Nigeria, between the hours of 10pm to 12am, and microscopically identified for microfilariae. W. bancrofti positive samples were cultured for 72h treated with Doxycycline (2μg/ml) and kolaviron (5μg/ml) in vitro. Mitotic index, expression of vascular endothelial growth factor-C (VEGF-c), toll like receptor-2 (TLR-2) were determined using standard procedures...
June 12, 2017: Journal of Infection and Public Health
https://www.readbyqxmd.com/read/28619407/should-they-also-have-babies-community-attitudes-toward-sexual-and-reproductive-rights-of-people-living-with-hiv-aids-in-nigeria
#20
Zubairu Iliyasu, Hadiza S Galadanci, Yusuf A Ibrahim, Musa Babashani, Mohammed S Mijinyawa, Melynda Simmons, Muktar H Aliyu
BACKGROUND: People living with HIV have the right to healthy, satisfying sex lives and to appropriate services to ensure their sexual and reproductive health, including having healthy children. The reproductive rights of people living with HIV/AIDS are, however, often met with skepticism and discrimination, despite recent advances in HIV treatment. OBJECTIVE: To assess the attitudes of community members in Kano, Nigeria, toward the right of persons living with HIV/AIDS to have healthy sexual relationships and bear children...
March 2017: Annals of Global Health
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