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Macular pucker

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https://www.readbyqxmd.com/read/28314834/internal-limiting-membrane-peeling-or-not-a-systematic-review-and-meta-analysis-of-idiopathic-macular-pucker-surgery
#1
Xiao-Ling Fang, Yao Tong, Ya-Li Zhou, Pei-Quan Zhao, Zhao-Yang Wang
PURPOSE: To determine whether internal limiting membrane (ILM) peeling improves anatomical and functional outcomes in idiopathic macular pucker (IMP)/epiretinal membrane (ERM) surgery in this systematic review and meta-analysis. METHODS: We searched the PubMed, Medline, Web of Science, Cochrane, Ovid MEDLINE, ClinicalTrials.gov and CNKI databases for studies published before 15 September 2016. The eligibility criteria included studies comparing ILM peeling versus no-peeling for IMP surgery...
March 17, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28237428/slow-release-dexamethasone-in-proliferative-vitreoretinopathy-a-prospective-randomized-controlled-clinical-trial
#2
Philip J Banerjee, Ana Quartilho, Catey Bunce, Wen Xing, Tapiwa M Zvobgo, Nicola Harris, David G Charteris
PURPOSE: To test the hypothesis that adjunctive slow-release dexamethasone implant (Ozurdex; Allergan Inc, Irvine, CA) can improve the outcomes of vitreoretinal surgery for established proliferative vitreoretinopathy (PVR). DESIGN: A 2-year, single-center, prospective, participant- and surgeon-masked randomized controlled clinical trial (EudraCT No. 2011-004498-96). PARTICIPANTS: A total of 140 patients requiring vitrectomy surgery with silicone oil for retinal detachment with established PVR (Grade C) were randomized to standard (control) or study treatment (adjunct) in a 1:1 allocation ratio...
February 22, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28151841/visualization-of-macular-pucker-by-multicolor-scanning-laser-imaging
#3
Ilkay Kilic Muftuoglu, Dirk-Uwe Bartsch, Giulio Barteselli, Raouf Gaber, Joseph Nezgoda, William R Freeman
PURPOSE: To compare the visualization of the epiretinal membrane (ERM) using multicolor imaging (MCI) (Heidelberg Engineering, Carlsbad, CA) and conventional white light flood color fundus photography (FP) (Topcon). METHODS: The paired images of patients with ERM who underwent same-day MCI and FP examinations were reviewed. Visibility of the ERM was graded using a scale (0: not visible, 1: barely visible, and 2: clearly visible) by masked readers, and surface folds were counted to quantify the membrane visibility for each method...
February 1, 2017: Retina
https://www.readbyqxmd.com/read/28004156/-intramuscular-depot-steroids-possible-treatment-of-postsurgical-cystoid-macula-edema-with-steroid-response
#4
A-M Seuthe, P Szurman, K T Boden
We report on a patient with postsurgical cystoid macular edema (CME) after phacoemulsification and multifocal intraocular lens (MIOL) implantation. At first, there was a very good reaction to intravitreal triamcinolone, inducing complete regression of the edema without increasing intraocular pressure (IOP). One year later the patient suffered from retinal detachment and was treated with vitrectomy, laser, and gas tamponade. Afterward, he developed macular pucker with edema. After surgical treatment with pucker peeling and intravitreal triamcinolone, the patient showed a steroid response and an increase IOP...
December 21, 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/27833968/posterior-vitreous-detachment-and-macular-anatomical-changes-a-tomographic-electroretinographic-study
#5
Alin Ştefan Ştefănescu-Dima, Cornelia Andreea Corîci, Maria Rodica Mănescu, Teodor Nicuşor Sas, Maria Iancău, Carmen LuminiŢa Mocanu
AIM: Posterior vitreous detachment (PVD) is a physiological phenomenon due to aging characterized by separation of the vitreous cortex from the retina and may induce a variety of pathological events at the vitreoretinal junction. The aim of this study is to highlight in vivo anatomical and functional changes in early stages of PVD allowing the correct treatment. MATERIAL AND METHODS: Non-consecutive case series; optical coherence tomography (OCT) relies on analyzing the reflectivity of coherent light from different anatomical interfaces within posterior vitreous and retinal histological layers, thus acquiring transverse sections through vitreoretinal interface, sensory retina, retinal pigment epithelium and choroid...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/27833926/bilateral-papilledema-in-a-child-with-osteogenesis-imperfecta
#6
Selam Yekta Sendul, Cemile Ucgul Atilgan, Semra Tiryaki, Dilek Guven
BACKGROUND: To present a female child patient with osteogenesis imperfecta who had bilateral papilledema. CASE PRESENTATION: A twelve-year-old girl with osteogenesis imperfecta was referred to our clinic. Bilateral best corrected visual acuity of the patient was 5/10 (corrected with +3.50 for right eye, +5.00 for left eye) with a standard Snellen scale at a distance of a 6 m. Anterior chamber, iris and lens examination of both of her eyes were unremarkable. In her fundus examination, bilateral stage 2 papilledema and the wrinkles in papillomacular area were noticed...
2016: Eye and Vision (London, England)
https://www.readbyqxmd.com/read/27780174/clinical-spectrum-of-macular-foveal-capillaries-evaluated-with-optical-coherence-tomography-angiography
#7
Maria V Cicinelli, Adriano Carnevali, Alessandro Rabiolo, Lea Querques, Ilaria Zucchiatti, Vincenzo Scorcia, Francesco Bandello, Giuseppe Querques
PURPOSE: To describe macular-foveal capillaries (MFC) by means of optical coherence tomography angiography and to identify the clinical spectrum of this angiographic feature. METHODS: Patients with MFC presenting at the Medical Retina & Imaging Unit of the Department of Ophthalmology, University Vita-Salute San Raffaele in Milan were recruited. Patients underwent a complete ophthalmologic examination that included slit-lamp examination, fundus examination, measurement of best-corrected visual acuity, fundus autofluorescence, and spectral-domain optical coherence tomography (Spectralis HRA + OCT; Heidelberg Engineering, Heidelberg, Germany)...
March 2017: Retina
https://www.readbyqxmd.com/read/27638339/deregulation-of-ocular-nucleotide-homeostasis-in-patients-with-diabetic-retinopathy
#8
Sirpa Loukovaara, Jouko Sandholm, Kristiina Aalto, Janne Liukkonen, Sirpa Jalkanen, Gennady G Yegutkin
Clear signaling roles for ATP and adenosine have been established in all tissues, including the eye. The magnitude of signaling responses is governed by networks of enzymes; however, little is known about the regulatory mechanisms of purinergic signaling in the eye. By employing thin-layer chromatographic assays with (3)H-labeled substrates, this study aimed to evaluate the role of nucleotide homeostasis in the pathogenesis of vitreoretinal diseases in humans. We have identified soluble enzymes ecto-5'-nucleotidase/CD73, adenylate kinase-1, and nucleoside diphosphate kinase in the vitreous fluid that control active cycling between pro-inflammatory ATP and anti-inflammatory adenosine...
September 16, 2016: Journal of Molecular Medicine: Official Organ of the "Gesellschaft Deutscher Naturforscher und Ärzte"
https://www.readbyqxmd.com/read/27497808/plasmin-enzyme-assisted-vitrectomy-in-pediatric-patients-with-vitreoretinal-diseases
#9
Yung-Sung Lee, Nan-Kai Wang, Yen-Po Chen, Kuan-Jen Chen, Yih-Shiou Hwang, Chi-Chun Lai, Wei-Chi Wu
PURPOSE: To evaluate the efficacy and safety of using plasmin-assisted vitrectomy in pediatric patients with vitreoretinal diseases. METHODS: We prospectively recruited children aged 16 years or younger who presented with vitreoretinopathies and underwent plasmin-assisted vitrectomy between 2012 and 2013. The main outcome measure was the induction of posterior vitreous detachment (PVD) using a suction power of 200 mm Hg or less during surgery. RESULTS: Eleven eyes of 11 patients (mean age: 3...
2016: Ophthalmic Research
https://www.readbyqxmd.com/read/27373390/refractive-outcomes-after-phacovitrectomy-surgery
#10
Leonie J van der Geest, Martin J Siemerink, Marco Mura, Maarten P Mourits, Ruth Lapid-Gortzak
PURPOSE: To evaluate the refractive accuracy of intraocular lens (IOL) power calculation after phacovitrectomy. SETTING: Eye Hospital Zonnestraal and Department of Ophthalmology Academic Medical Center, Amsterdam, the Netherlands. DESIGN: Retrospective comparative case series. METHODS: Refraction results 1 month after phacovitrectomy or phacoemulsification were compared with predicted refractions calculated using the IOLMaster 500 and the Haigis formula...
June 2016: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/27190635/two-dimensional-cutting-tdc-vitrectome-in-vitro-flow-assessment-and-prospective-clinical-study-evaluating-core-vitrectomy-efficiency-versus-standard-vitrectome
#11
Mitrofanis Pavlidis
Purpose. To evaluate comparative aspiration flow performance and also vitrectomy operating time efficiency using a double-cutting open port vitreous cutting system incorporated in a two-dimensional cutting (TDC, DORC International) vitrectome design versus standard vitreous cutter. Methods. In vitro investigations compared aspiration flow rates in artificial vitreous humor at varying cutter speeds and vacuum levels using a TDC vitrectome and a standard vitrectome across different aspiration pump systems. A prospective single-centre clinical study evaluated duration of core vitrectomy in 80 patients with macular pucker undergoing 25-gauge or 27-gauge vitrectomy using either a TDC vitrectome at 16,000 cuts per minute (cpm) or standard single-cut vitrectome, combined with a Valve Timing intelligence (VTi) pump system (EVA, DORC International)...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27171917/epiretinal-membrane-formation-after-intravitreal-autologous-stem-cell-implantation-in-a-retinitis-pigmentosa-patient
#12
Ju Young Kim, Yong Sung You, Soon Hyun Kim, Oh Woong Kwon
METHODS: A retrospective case report of a retinitis pigmentosa patient who underwent vitrectomy for epiretinal membrane after intravitreal autologous stem cell implantation. RESULTS: A 71-year-old female RP patient came to our clinic for ophthalmic evaluation after intravitreal autologous stem cell injection. Four months ago, she underwent intravitreal autologous stem cell injection for both eyes at another hospital. New thick epiretinal membrane (ERM) with extensive macular pucker was found on her left eye...
May 11, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27129901/quantifying-visual-dysfunction-and-the-response-to-surgery-in-macular-pucker
#13
Justin H Nguyen, Kenneth M Yee, Alfredo A Sadun, J Sebag
PURPOSE: To measure the effects of macular pucker (MP) on macular structure and quantify function by measuring visual acuity (VA), contrast sensitivity (CS), and distortions. The effects of surgery were quantitatively evaluated using these measures. DESIGN: Prospective, comparative case series. PARTICIPANTS: Fifty-three patients with unilateral MP and normal fellow eyes: 24 operated MP subjects, 17 unoperated controls, and 12 reproducibility subjects...
July 2016: Ophthalmology
https://www.readbyqxmd.com/read/26968718/comparison-of-four-surgical-techniques-for-management-of-pseudophakic-and-aphakic-retinal-detachment-a-multicenter-clinical-trial
#14
Siamak Moradian, Hamid Ahmadieh, Hooshang Faghihi, Alireza Ramezani, Morteza Entezari, Touka Banaee, Ebadollah Heidari, Hassan Behboudi, Mehdi Yasseri
PURPOSE: To compare the visual and anatomical outcomes of four surgical techniques to manage pseudophakic and aphakic retinal detachment (PARD). METHODS: In a multicenter randomized clinical trial, 211 eyes of 211 patients with PARD and proliferative vitreoretinopathy (PVR) grade B or less were randomly assigned to one of the four treatment groups: (1) scleral buckling (SB), 50 eyes, (2) vitrectomy without band, 51 eyes, (3) vitrectomy with encircling band (EB), 58 eyes, and (4) triamcinolone acetonide (TA) assisted vitrectomy, 52 eyes...
September 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/26915745/the-kinetics-of-vegf-and-mcp-1-in-the-second-vitrectomy-cases-with-proliferative-diabetic-retinopathy
#15
Y Sassa, S Yoshida, K Ishikawa, R Asato, T Ishibashi, T Kono
PurposeTo determine whether the concentrations of vascular endothelial growth factor (VEGF) and monocyte chemoattractant protein (MCP)-1 in the vitreous changed after vitrectomy in patients with proliferative diabetic retinopathy (PDR).ParticipantsTwenty-one eyes of 21 patients who needed a second surgery for PDR were included. The reasons for the second surgery were tractional retinal detachment (TRD), neovascular glaucoma, persistent vitreous hemorrhage, macular pucker, and secondary intraocular lens (IOL) implant...
2016: Eye
https://www.readbyqxmd.com/read/26914992/long-term-evolution-of-dome-shaped-macula-increased-macular-bulge-is-associated-with-extended-macular-atrophy
#16
MULTICENTER STUDY
Guillaume Soudier, Alain Gaudric, Vincent Gualino, Pascale Massin, Mathieu Nardin, Ramin Tadayoni, Claude Speeg-Schatz, David Gaucher
PURPOSE: Dome-shaped macula (DSM) may cause impaired vision. This study analyzed the long-term evolution of DSM, most particularly macular changes: serous retinal detachment, retinal pigment epithelium atrophy, and DSM bulge increase. METHODS: Twenty-nine eyes presenting with DSM were retrospectively studied. Clinical data, color photographs, fluorescein angiographs, and optical coherence tomography examinations were reviewed. Patients were followed up from 6 months to 111 months (mean, 37...
May 2016: Retina
https://www.readbyqxmd.com/read/26562569/reduction-of-vitreous-prostaglandin-e2-levels-after-topical-administration-of-indomethacin-0-5-bromfenac-0-09-and-nepafenac-0-1
#17
RANDOMIZED CONTROLLED TRIAL
Andrea Russo, Francesco Morescalchi, Sara Vezzoli, Marzia Bernini, Raffaele Turano, Ciro Costagliola, Francesco De Ferrari, Francesco Semeraro
PURPOSE: To assess vitreous concentrations of nonsteroidal anti-inflammatory drugs (NSAIDs) and prostaglandin E2 (PGE2) in patients treated with NSAIDs before vitrectomy for macular pucker. METHODS: A prospective, investigator-masked, randomized study was performed in 64 patients scheduled to undergo vitrectomy. The patients were randomized 1:1:1:1 to receive indomethacin 0.5%, bromfenac 0.09%, nepafenac 0.1%, or placebo three times a day. NSAIDs and PGE2 levels were evaluated in vitreous samples collected at the beginning of surgery...
June 2016: Retina
https://www.readbyqxmd.com/read/26465616/vitreoretinal-surgical-outcomes-performed-by-supervised-retinal-fellows-versus-attending-faculty-surgeons
#18
COMMENT
John O Mason, Lauren B Mason, Shyam A Patel, Gerald McGwin, Thomas A Finley, Duncan A Friedman, Dustin L Pomerleau, Michael A Albert, Richard M Feist, Martin L Thomley, John O Mason
PURPOSE: To evaluate common vitreoretinal surgeries performed by retinal fellows under direct faculty supervision, compared with experienced faculty members. METHODS: Retrospective study analyzing 592 consecutive eyes undergoing retinal surgery from 2009 to 2011 at Retina Consultants of Alabama/University of Alabama at Birmingham, Department of Ophthalmology. Vitreoretinal surgeries included macular hole, macular pucker, retinal detachment, diabetic vitreous hemorrhage, and diabetic tractional retinal detachment...
May 2016: Retina
https://www.readbyqxmd.com/read/26421182/functional-and-morphological-correlations-before-and-after-video-documented-23-gauge-pars-plana-vitrectomy-with-membrane-and-ilm-peeling-in-patients-with-macular-pucker
#19
Wolfgang J Mayer, Clara Fazekas, Ricarda Schumann, Armin Wolf, Denise Compera, Anselm Kampik, Christos Haritoglou
Purpose. To assess functional and morphological alterations following video-documented surgery for epiretinal membranes. Methods. Forty-two patients underwent video-documented 23-gauge vitrectomy with peeling of epiretinal (ERM) and inner limiting membrane (ILM). Patient assessment was performed before and 3 and 6 months including best corrected visual acuity (BCVA), slit lamp biomicroscopy, SD-OCT, and central 2° and 18° microperimetry. In addition, all video-documented areas of peeling on the retinal surface were evaluated postoperatively using an additional focal 2° microperimetry...
2015: Journal of Ophthalmology
https://www.readbyqxmd.com/read/26285163/the-impact-of-ranibizumab-on-the-level-of%C3%A2-intercellular-adhesion-molecule-type-1-in-the-vitreous%C3%A2-of%C3%A2-eyes-with-proliferative-diabetic-retinopathy
#20
Ying Yan, Li Zhu, Ling Hong, Jun Deng, Yanpin Song, Xiao Chen
PURPOSE: This study was to investigate the impact of ranibizumab on the level of intercellular adhesion molecule type 1 (ICAM-1) in the vitreous of eyes with PDR. METHODS: This is an interventional case-control study. A total of 82 eyes from 82 patients who had undergone vitreous surgery for the treatment of retinal disorders were included. Twenty-two eyes with PDR received an intravitreal ranibizumab injection (IVR) 3-7 days before vitrectomy and were grouped as 'PDR with recent IVR' or Group 1...
June 2016: Acta Ophthalmologica
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