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Macular pucker

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https://www.readbyqxmd.com/read/28782074/a-cell-culture-technique-for-human-epiretinal-membranes-to-describe-cell-behavior-and-membrane-contraction-in-vitro
#1
Christian Wertheimer, Kirsten H Eibl-Lindner, Denise Compera, Alexander Kueres, Armin Wolf, Denitsa Docheva, Siegfried G Priglinger, Claudia Priglinger, Ricarda G Schumann
PURPOSE: To introduce a human cell culture technique for investigating in-vitro behavior of primary epiretinal cells and membrane contraction of fibrocellular tissue surgically removed from eyes with idiopathic macular pucker. METHODS: Human epiretinal membranes were harvested from ten eyes with idiopathic macular pucker during standard vitrectomy. Specimens were fixed on cell culture plastic using small entomological pins to apply horizontal stress to the tissue, and then transferred to standard cell culture conditions...
August 7, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28723849/comparative-analysis-of-retinal-reattachment-surgery-with-or-without-internal-limiting-membrane-peeling-to-prevent-postoperative-macular-pucker
#2
Matteo Forlini, Purva Date, Luisa Micelli Ferrari, Massimo Lorusso, Gabriella Lecce, Tommaso Verdina, Giovanni Neri, Caterina Benatti, Paolo Rossini, Adriana Bratu, Domenico DʼEliseo, Tommaso Micelli Ferrari, Gian Maria Cavallini
PURPOSE: To determine whether internal limiting membrane (ILM) peeling during pars plana vitrectomy for rhegmatogenous retinal detachment reduces the incidence of epiretinal membrane (ERM) formation. METHODS: In this retrospective study, preoperative, intraoperative, and postoperative data from all eyes undergoing pars plana vitrectomy for rhegmatogenous retinal detachment between January 2007 and December 2013 was analyzed. All cases with at least 1-year of follow-up were included...
July 18, 2017: Retina
https://www.readbyqxmd.com/read/28556420/impact-of-postoperative-positioning-on-the-outcome-of-pars-plana-vitrectomy-with-gas-tamponade-for-primary-rhegmatogenous-retinal-detachment-comparison-between-supine-and-prone-positioning
#3
Keiko Otsuka, Hisanori Imai, Akiko Miki, Makoto Nakamura
PURPOSE: To compare the postoperative anatomic success rates and the frequency of complications between prone or supine postoperative positioning after transconjunctival sutureless vitrectomy (TSV) for rhegmatogenous retinal detachment (RRD). METHODS: All patients underwent primary 27-gauge TSV for the treatment of primary RRD. Patients were divided into two groups as follows: group A was patients instructed to keep strict postoperative prone positioning for a minimum of 8 days...
May 27, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28463851/intravitreal-sustained-release-steroid-implants-for-the-treatment-of-macular-edema-following-surgical-removal-of-epiretinal-membranes
#4
Lars-Olof Hattenbach, Christina Springer-Wanner, Hans Hoerauf, Josep Callizo, Stephanie Jungmann, Thomas Brauns, Gergana Fulle, Sebastian Eichel, Michael Janusz Koss, Claudia Kuhli-Hattenbach
PURPOSE: To evaluate the efficacy of intravitreal dexamethasone implant for the treatment of postoperative persistent cystoid macular edema (CME) following macular pucker surgery. METHODS: In this multicenter study, we retrospectively reviewed the data of 37 patients (39 eyes) who had been treated with intravitreal dexamethasone implant (Ozurdex®) for persistent CME following macular pucker surgery. Main outcome measures were change in best-corrected visual acuity (BCVA) and central retinal thickness (CRT)...
2017: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/28452991/focal-choroidal-excavation-morphological-features-and-clinical-correlation
#5
C Y Chung, S H Li, K K W Li
PurposeTo describe and correlate the morphological and clinical features of focal choroidal excavation (FCE).MethodsThis is a consecutive case series from the review of the 4436 optical coherence tomography scans performed by Kowloon East Cluster Ophthalmic Service from 1 August 2014-31 January 2016. Statistical analysis was performed on SPSS 18.0 (SPSS, Chicago, IL, USA). A significance level of P<0.05 was taken.ResultsAll 16 patients with FCE had unilateral involvement. The mean age of diagnosis was 52...
April 28, 2017: Eye
https://www.readbyqxmd.com/read/28376039/residual-intraretinal-edema-after-25-gauge-vitrectomy-and-macular-pucker-removal-is-intraoperative-sustained-release-dexamethasone-a-real-treatment-option
#6
Gianluca Guidi, Giamberto Casini, Guido Ripandelli, Paolo Piaggi, Flavio Dalle Lucche, Mariasole Sartini, Pasquale Loiudice, Francesco Nasini, Mario Stirpe, Stefano Lazzeri
PURPOSE: To investigate the efficacy and safety of intraoperative slow-release dexamethasone implant and 25-gauge (G) vitrectomy plus epiretinal membrane removal in patients affected by idiopathic macular pucker. METHODS: In this randomized, clinical, multicenter study, 60 eyes of 60 pseudophakic eyes having idiopathic macular pucker were enrolled. Thirty eyes underwent 25-G pars plana vitrectomy and internal limiting membrane peeling ("Control group"), whereas 30 eyes underwent 25-G pars plana vitrectomy and internal limiting membrane peeling combined with dexamethasone implant ("DEX group")...
April 3, 2017: Retina
https://www.readbyqxmd.com/read/28333880/twenty-five-gauge-pars-plana-vitrectomy-in-complex-retinal-detachments-associated-with-giant-retinal-tear
#7
Vinod Kumar, Devesh Kumawat, Anju Bhari, Parijat Chandra
PURPOSE: To study the structural and functional outcomes of 25-gauge pars plana vitrectomy in giant retinal tear-associated retinal detachments. METHODS: Seventeen eyes of 17 patients with giant retinal tear, who underwent 25-gauge pars plana vitrectomy over a period of 15 months at a tertiary eye care center by a single surgeon, were recruited in this retrospective interventional study. RESULTS: Giant retinal tears were mostly traumatic (35...
March 22, 2017: Retina
https://www.readbyqxmd.com/read/28314834/internal-limiting-membrane-peeling-or-not-a-systematic-review-and-meta-analysis-of-idiopathic-macular-pucker-surgery
#8
Xiao-Ling Fang, Yao Tong, Ya-Li Zhou, Pei-Quan Zhao, Zhao-Yang Wang
PURPOSE: To determine whether internal limiting membrane (ILM) peeling improves anatomical and functional outcomes in idiopathic macular pucker (IMP)/epiretinal membrane (ERM) surgery in this systematic review and meta-analysis. METHODS: We searched the PubMed, Medline, Web of Science, Cochrane, Ovid MEDLINE, ClinicalTrials.gov and CNKI databases for studies published before 15 September 2016. The eligibility criteria included studies comparing ILM peeling versus no-peeling for IMP surgery...
March 17, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28237428/slow-release-dexamethasone-in-proliferative-vitreoretinopathy-a-prospective-randomized-controlled-clinical-trial
#9
RANDOMIZED CONTROLLED TRIAL
Philip J Banerjee, Ana Quartilho, Catey Bunce, Wen Xing, Tapiwa M Zvobgo, Nicola Harris, David G Charteris
PURPOSE: To test the hypothesis that adjunctive slow-release dexamethasone implant (Ozurdex; Allergan Inc, Irvine, CA) can improve the outcomes of vitreoretinal surgery for established proliferative vitreoretinopathy (PVR). DESIGN: A 2-year, single-center, prospective, participant- and surgeon-masked randomized controlled clinical trial (EudraCT No. 2011-004498-96). PARTICIPANTS: A total of 140 patients requiring vitrectomy surgery with silicone oil for retinal detachment with established PVR (Grade C) were randomized to standard (control) or study treatment (adjunct) in a 1:1 allocation ratio...
June 2017: Ophthalmology
https://www.readbyqxmd.com/read/28151841/visualization-of-macular-pucker-by-multicolor-scanning-laser-imaging
#10
Ilkay Kilic Muftuoglu, Dirk-Uwe Bartsch, Giulio Barteselli, Raouf Gaber, Joseph Nezgoda, William R Freeman
PURPOSE: To compare the visualization of the epiretinal membrane (ERM) using multicolor imaging (MCI) (Heidelberg Engineering, Carlsbad, CA) and conventional white light flood color fundus photography (FP) (Topcon). METHODS: The paired images of patients with ERM who underwent same-day MCI and FP examinations were reviewed. Visibility of the ERM was graded using a scale (0: not visible, 1: barely visible, and 2: clearly visible) by masked readers, and surface folds were counted to quantify the membrane visibility for each method...
February 1, 2017: Retina
https://www.readbyqxmd.com/read/28004156/-intramuscular-depot-steroids-possible-treatment-of-postsurgical-cystoid-macula-edema-with-steroid-response
#11
A-M Seuthe, P Szurman, K T Boden
We report on a patient with postsurgical cystoid macular edema (CME) after phacoemulsification and multifocal intraocular lens (MIOL) implantation. At first, there was a very good reaction to intravitreal triamcinolone, inducing complete regression of the edema without increasing intraocular pressure (IOP). One year later the patient suffered from retinal detachment and was treated with vitrectomy, laser, and gas tamponade. Afterward, he developed macular pucker with edema. After surgical treatment with pucker peeling and intravitreal triamcinolone, the patient showed a steroid response and an increase IOP...
December 21, 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/27833968/posterior-vitreous-detachment-and-macular-anatomical-changes-a-tomographic-electroretinographic-study
#12
Alin Ştefan Ştefănescu-Dima, Cornelia Andreea Corîci, Maria Rodica Mănescu, Teodor Nicuşor Sas, Maria Iancău, Carmen LuminiŢa Mocanu
AIM: Posterior vitreous detachment (PVD) is a physiological phenomenon due to aging characterized by separation of the vitreous cortex from the retina and may induce a variety of pathological events at the vitreoretinal junction. The aim of this study is to highlight in vivo anatomical and functional changes in early stages of PVD allowing the correct treatment. MATERIAL AND METHODS: Non-consecutive case series; optical coherence tomography (OCT) relies on analyzing the reflectivity of coherent light from different anatomical interfaces within posterior vitreous and retinal histological layers, thus acquiring transverse sections through vitreoretinal interface, sensory retina, retinal pigment epithelium and choroid...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/27833926/bilateral-papilledema-in-a-child-with-osteogenesis-imperfecta
#13
Selam Yekta Sendul, Cemile Ucgul Atilgan, Semra Tiryaki, Dilek Guven
BACKGROUND: To present a female child patient with osteogenesis imperfecta who had bilateral papilledema. CASE PRESENTATION: A twelve-year-old girl with osteogenesis imperfecta was referred to our clinic. Bilateral best corrected visual acuity of the patient was 5/10 (corrected with +3.50 for right eye, +5.00 for left eye) with a standard Snellen scale at a distance of a 6 m. Anterior chamber, iris and lens examination of both of her eyes were unremarkable. In her fundus examination, bilateral stage 2 papilledema and the wrinkles in papillomacular area were noticed...
2016: Eye and Vision (London, England)
https://www.readbyqxmd.com/read/27780174/clinical-spectrum-of-macular-foveal-capillaries-evaluated-with-optical-coherence-tomography-angiography
#14
Maria V Cicinelli, Adriano Carnevali, Alessandro Rabiolo, Lea Querques, Ilaria Zucchiatti, Vincenzo Scorcia, Francesco Bandello, Giuseppe Querques
PURPOSE: To describe macular-foveal capillaries (MFC) by means of optical coherence tomography angiography and to identify the clinical spectrum of this angiographic feature. METHODS: Patients with MFC presenting at the Medical Retina & Imaging Unit of the Department of Ophthalmology, University Vita-Salute San Raffaele in Milan were recruited. Patients underwent a complete ophthalmologic examination that included slit-lamp examination, fundus examination, measurement of best-corrected visual acuity, fundus autofluorescence, and spectral-domain optical coherence tomography (Spectralis HRA + OCT; Heidelberg Engineering, Heidelberg, Germany)...
March 2017: Retina
https://www.readbyqxmd.com/read/27638339/deregulation-of-ocular-nucleotide-homeostasis-in-patients-with-diabetic-retinopathy
#15
Sirpa Loukovaara, Jouko Sandholm, Kristiina Aalto, Janne Liukkonen, Sirpa Jalkanen, Gennady G Yegutkin
Clear signaling roles for ATP and adenosine have been established in all tissues, including the eye. The magnitude of signaling responses is governed by networks of enzymes; however, little is known about the regulatory mechanisms of purinergic signaling in the eye. By employing thin-layer chromatographic assays with (3)H-labeled substrates, this study aimed to evaluate the role of nucleotide homeostasis in the pathogenesis of vitreoretinal diseases in humans. We have identified soluble enzymes ecto-5'-nucleotidase/CD73, adenylate kinase-1, and nucleoside diphosphate kinase in the vitreous fluid that control active cycling between pro-inflammatory ATP and anti-inflammatory adenosine...
September 16, 2016: Journal of Molecular Medicine: Official Organ of the "Gesellschaft Deutscher Naturforscher und Ärzte"
https://www.readbyqxmd.com/read/27497808/plasmin-enzyme-assisted-vitrectomy-in-pediatric-patients-with-vitreoretinal-diseases
#16
Yung-Sung Lee, Nan-Kai Wang, Yen-Po Chen, Kuan-Jen Chen, Yih-Shiou Hwang, Chi-Chun Lai, Wei-Chi Wu
PURPOSE: To evaluate the efficacy and safety of using plasmin-assisted vitrectomy in pediatric patients with vitreoretinal diseases. METHODS: We prospectively recruited children aged 16 years or younger who presented with vitreoretinopathies and underwent plasmin-assisted vitrectomy between 2012 and 2013. The main outcome measure was the induction of posterior vitreous detachment (PVD) using a suction power of 200 mm Hg or less during surgery. RESULTS: Eleven eyes of 11 patients (mean age: 3...
2016: Ophthalmic Research
https://www.readbyqxmd.com/read/27373390/refractive-outcomes-after-phacovitrectomy-surgery
#17
Leonie J van der Geest, Martin J Siemerink, Marco Mura, Maarten P Mourits, Ruth Lapid-Gortzak
PURPOSE: To evaluate the refractive accuracy of intraocular lens (IOL) power calculation after phacovitrectomy. SETTING: Eye Hospital Zonnestraal and Department of Ophthalmology Academic Medical Center, Amsterdam, the Netherlands. DESIGN: Retrospective comparative case series. METHODS: Refraction results 1 month after phacovitrectomy or phacoemulsification were compared with predicted refractions calculated using the IOLMaster 500 and the Haigis formula...
June 2016: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/27190635/two-dimensional-cutting-tdc-vitrectome-in-vitro-flow-assessment-and-prospective-clinical-study-evaluating-core-vitrectomy-efficiency-versus-standard-vitrectome
#18
Mitrofanis Pavlidis
Purpose. To evaluate comparative aspiration flow performance and also vitrectomy operating time efficiency using a double-cutting open port vitreous cutting system incorporated in a two-dimensional cutting (TDC, DORC International) vitrectome design versus standard vitreous cutter. Methods. In vitro investigations compared aspiration flow rates in artificial vitreous humor at varying cutter speeds and vacuum levels using a TDC vitrectome and a standard vitrectome across different aspiration pump systems. A prospective single-centre clinical study evaluated duration of core vitrectomy in 80 patients with macular pucker undergoing 25-gauge or 27-gauge vitrectomy using either a TDC vitrectome at 16,000 cuts per minute (cpm) or standard single-cut vitrectome, combined with a Valve Timing intelligence (VTi) pump system (EVA, DORC International)...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27171917/epiretinal-membrane-formation-after-intravitreal-autologous-stem-cell-implantation-in-a-retinitis-pigmentosa-patient
#19
Ju Young Kim, Yong Sung You, Soon Hyun Kim, Oh Woong Kwon
METHODS: A retrospective case report of a retinitis pigmentosa patient who underwent vitrectomy for epiretinal membrane after intravitreal autologous stem cell implantation. RESULTS: A 71-year-old female RP patient came to our clinic for ophthalmic evaluation after intravitreal autologous stem cell injection. Four months ago, she underwent intravitreal autologous stem cell injection for both eyes at another hospital. New thick epiretinal membrane (ERM) with extensive macular pucker was found on her left eye...
July 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27129901/quantifying-visual-dysfunction-and-the-response-to-surgery-in-macular-pucker
#20
COMPARATIVE STUDY
Justin H Nguyen, Kenneth M Yee, Alfredo A Sadun, J Sebag
PURPOSE: To measure the effects of macular pucker (MP) on macular structure and quantify function by measuring visual acuity (VA), contrast sensitivity (CS), and distortions. The effects of surgery were quantitatively evaluated using these measures. DESIGN: Prospective, comparative case series. PARTICIPANTS: Fifty-three patients with unilateral MP and normal fellow eyes: 24 operated MP subjects, 17 unoperated controls, and 12 reproducibility subjects...
July 2016: Ophthalmology
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