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https://www.readbyqxmd.com/read/28444681/-wolf-hirschhorn-syndrome-description-of-a-spanish-cohort-of-51-cases-and-a-literature-review
#1
R Blanco-Lago, I Malaga-Dieguez, J J Granizo-Martinez, L Carrera-Garcia, P Barruz-Galian, P Lapunzina, J Nevado-Blanco, En Representacion Del Grupo Colaborativo Para El Estudio Del Sindrome de Wolf-Hirschhorn En Representacion Del Grupo Colaborativo Para El Estudio Del Sindrome de Wolf-Hirschhorn
INTRODUCTION: Wolf-Hirschhorn syndrome (WHS) is a contiguous gene syndrome that gives rise to multiple congenital anomalies, caused by the loss of a distal portion of the short arm of chromosome 4 (4p16.3). It is characterised by its own peculiar facial phenotype, associated to growth problems, psychomotor retardation and epilepsy. AIMS: To establish a register of patients with WHS in Spain, describe their characteristics, determine the prevalence of epilepsy, estimate the degree of psychomotor retardation and perform a review of the literature in order to compare these data with those published to date...
May 1, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/28441638/health-risk-assessment-for-the-consumption-of-fresh-and-preserved-fish-alosa-agone-from-lago-di-como-northern-italy
#2
Silvia Quadroni, Roberta Bettinetti
BACKGROUND: Although banned in many countries for decades, DDTs and PCBs still represent a global threat to food safety. As these contaminants are still present in aquatic ecosystems, fish can be an important contributor to their total dietary intake. OBJECTIVES: Alosa agone specimens were sampled over a period of 10 years (from 2006 to 2015) to provide a representative overview of the DDT and PCB levels of Lago di Como, a deep Italian lake where a DDT input due to secondary sources was observed in recent years...
April 22, 2017: Environmental Research
https://www.readbyqxmd.com/read/28435027/exercise-modulated-epigenetic-markers-and-inflammatory-response-in-copd-individuals-a-pilot-study
#3
Ivy Reichert Vital da Silva, Cintia Laura Pereira de Araujo, Gilson Pires Dorneles, Alessandra Peres, Andreia Luciana Bard, Gustavo Reinaldo, Paulo José Zimermann Teixeira, Pedro Dal Lago, Viviane Rostirola Elsner
The study investigated the effects of exercise on epigenetic signals and systemic cytokine levels in chronic obstructive pulmonary disease (COPD) individuals. Ten participants of a pulmonary rehabilitation program were submitted to 24 sessions of a supervisioned exercise protocol thrice-weekly (90min/session). Blood samples were collected at baseline, after the 1st session, before and after the 24th session. A DNA hypomethylation status was observed after the 1st session when compared at baseline, while global histone H4 acetylation status was unaltered in any time-points evaluated...
April 19, 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/28433520/corrigendum-to-therapeutic-effect-of-ursolic-acid-in-experimental-visceral-leishmaniasis-int-j-parasitol-drugs-drug-resist-7-2017-1-11
#4
Jessica A Jesus, Thais N Fragoso, Eduardo S Yamamoto, Marcia D Laurenti, Marcelo S Silva, Aurea F Ferreira, João Henrique G Lago, Gabriela Santos-Gomes, Luiz Felipe D Passero
No abstract text is available yet for this article.
April 4, 2017: International Journal for Parasitology, Drugs and Drug Resistance
https://www.readbyqxmd.com/read/28429340/controlled-prospective-observational-study-on-the-efficiency-and-tolerability-of-a-combination-of-potential-nrf2-inducing-antioxidants-and-micronutrients-as-pre-treatment-for-icsi-in-dyspermic-patients-with-previous-failure
#5
R Rago, M Gallo, A Dal Lago, E Licata, G Paciotti, M Amodei, C Meneghini, C Fabiani, G Dani, C Liberanome, D Antonaci, R Corno, D Miriello, G Giuffrida, B Giammusso
OBJECTIVE: To evaluate the efficiency of pre-treatment in dyspermic males in IVF couples with a combination of micronutrients, for the purpose of improving the fertilization rate, the implantation rate and the outcome of the pregnancy. PATIENTS AND METHODS: This controlled prospective clinical study was performed in two medically assisted reproduction centers. 59 males with mild oligo-astheno-teratospermia (OAT) were admitted to the study. All of them had a history of previous in vitro fertilization (IVF) attempts with female partners aged < 40 diagnosed having tubal or idiopathic infertility...
April 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28422358/is-mean-platelet-volume-a-better-biomarker-in-pre-eclampsia
#6
Gustavo Vilchez, Moraima Lagos, Komal Kumar, Pedro Argoti
AIM: Platelet activation and destruction is a well recognized feature of pre-eclampsia, but the current literature is contradictory regarding the role of mean platelet volume (MPV) in the diagnosis of this condition. We investigated whether MPV, compared with other routine laboratory markers such as platelet count, is a more significant biomarker of pre-eclampsia, giving special attention to the intrapartum period. METHODS: Biochemical and hematological markers along pregnancy including MPV were compared retrospectively between pre-eclampsia and matched controls...
April 19, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28422037/ureteral-meatotomy-as-an-option-in-the-management-of-primary-obstructive-megaureter-in-neonates-and-infants
#7
Priscila Cardoso Braz, Fernanda Ghilardi Leão, Jovelino Quintino de Souza Leão, Luciano Silveira Onofre, Giselle Machado Campos de Oliveira, José Carnevale, Carlos Miguélez Lago
Differentiating between the cases of megaureter that require surgery and the ones in whom treatment can be delayed is challenging. A large number of surgical techniques for the treatment of POM been proposed aiming mainly to reduce renal damage by relieving the affected ureter. Resection of the affected ureteral segment followed by vesicoureteral reimplantation either with or without reduction ureteroplasty is the classic treatment, however posing a high rate of complications when performed in patients aged less than one year...
April 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28422033/-values-and-significances-of-the-xx-century-medicine
#8
Carlos Miguelez Lago
No abstract text is available yet for this article.
April 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28421755/increasing-radical-character-of-large-n-cyclacenes-unveiled-by-wavefunction-theory
#9
Stefano Battaglia, Noelia Faginas Lago, Dirk Andrae, Stefano Evangelisti, Thierry Leininger
We have investigated the radicality and the singlet-triplet energy gap of [ n ]cyclacenes (cyclic polyacenes) as a function of the system size for n even, from 6 to 22. The calculations are performed using the complete active space self-consistent field method and second-order n-electron valence perturbation theory. We present a systematic way for the selection of the active space in order to have a balanced description of the wavefunction as the size of the system increases. Moreover, we provide didactic insight into the failure of an approach based on a minimal active space...
April 19, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28407955/influence-of-ripeness-and-maceration-of-the-grapes-on-levels-of-furan-and-carbonyl-compounds-in-wine-simultaneous-quantitative-determination-and-assessment-of-the-exposure-risk-to-these-compounds
#10
Laura Oliveira Lago, Karine Primieri Nicolli, Aline Biasoto Marques, Claudia Alcaraz Zini, Juliane Elisa Welke
The validated method based on the use of headspace solid phase microextraction (HS-SPME) coupled with the comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometric detection (GC×GC/TOFMS) proved to be appropriate for this first simultaneous quantitative determination of six toxic compounds (formaldehyde, acetaldehyde, ethyl carbamate, furan, furfural and acrolein) found in wines. Acetaldehyde and acrolein coeluted with other wine compounds, which indicated that difficulties could arise if only one-dimensional gas chromatography was used for the determination of these compounds...
September 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28407014/prevalence-of-macrolide-and-fluoroquinolone-resistance-mediating-mutations-in-mycoplasma-genitalium-in-five-cities-in-russia-and-estonia
#11
Elena Shipitsyna, Tatiana Rumyantseva, Daniel Golparian, Guzel Khayrullina, Amaya C Lagos, Inna Edelstein, Kai Joers, Jörgen S Jensen, Alevtina Savicheva, Natalia Rudneva, Larisa Sukhanova, Roman Kozlov, Alexander Guschin, Magnus Unemo
BACKGROUND AND OBJECTIVE: Resistance in the sexually transmitted bacterium Mycoplasma genitalium to all recommended therapeutic antimicrobials have rapidly emerged. However, to date, internationally reported resistance surveillance data for M. genitalium strains circulating in Eastern Europe are entirely lacking. The aim of this study was to estimate the prevalence of macrolide and fluoroquinolone resistance-associated mutations in M. genitalium in four cities in Russia and one in Estonia, 2013-2016...
2017: PloS One
https://www.readbyqxmd.com/read/28406244/cortistatin-reduces-atherosclerosis-in-hyperlipidemic-apoe-deficient-mice-and-the-formation-of-foam-cells
#12
Virginia Delgado-Maroto, Raquel Benitez, Irene Forte-Lago, Maria Morell, Elena Maganto-Garcia, Luciana Souza-Moreira, Francisco O'Valle, Mario Duran-Prado, Andrew H Lichtman, Elena Gonzalez-Rey, Mario Delgado
Atherosclerosis is a chronic inflammatory cardiovascular disease that is responsible of high mortality worldwide. Evidence indicates that maladaptive autoimmune responses in the arterial wall play critical roles in the process of atherosclerosis. Cortistatin is a neuropeptide expressed in the vascular system and atherosclerotic plaques that regulates vascular calcification and neointimal formation, and inhibits inflammation in different experimental models of autoimmune diseases. Its role in inflammatory cardiovascular disorders is largely unexplored...
April 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28402310/treatment-of-urea-manufacturing-facility-effluent-by-hopea-odorata-and-khaya-ivorensis
#13
Sara Yavari, Amirhossein Malakahmad, Nasiman B Sapari, Saba Yavari
Phytoremediation is an environmentally friendly and sustainable alternative for treatment of nitrogen-enriched wastewaters. In this study, Ta-khian (Hopea odorata) and Lagos mahogany (Khaya ivorensis), two tropical timber plants, were investigated for their performances in treatment of urea manufacturing factory effluent with high nitrogen (N) content. Plant seedlings received four concentrations of N (190, 240, 290 and 340 mg/L N) in laboratory-scale constructed wetlands every 4 days for a duration of 8 weeks...
April 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28400925/children-with-transposition-of-the-great-arteries-should-they-actually-be-born-in-nigeria
#14
Barakat Adeola Animasahun, Akpoembele Deborah Madise-Wobo, Henry Olusegun Gbelee, Samuel Ilenre Omokhodion
AIM: To describe the clinical and echocardiographic features of Nigerian children with transposition of the great arteries and emphasize the need for collaboration with cardiac centres in the developed countries to be able to salvage the children. METHODS: Prospective and cross sectional involving consecutive patients diagnosed with transposition of the great arteries using clinical evaluation and echocardiography at the Paediatric Department of Lagos State University Teaching Hospital, Lagos Nigeria as part of a large study between January 2007 and December 2015...
March 26, 2017: World Journal of Cardiology
https://www.readbyqxmd.com/read/28398968/treadmill-walking-combined-with-anodal-transcranial-direct-current-stimulation-in-parkinson-disease-a-pilot-study-of-kinematic-and-neurophysiological-effects
#15
Helena Fernández-Lago, Olalla Bello, Francina Mora-Cerdá, Jorge Montero-Cámara, Miguel Ángel Fernández-Del-Olmo
OBJECTIVE: We tested the hypothesis that combining treadmill walking with transcranial direct current stimulation (tDCS) enhances the gait improvements associated with treadmill walking in Parkinson disease. We explored the effects of these combined methodologies on corticospinal parameters. DESIGN: Eighteen participants with Parkinson disease were evaluated under the following three conditions: treadmill walking alone (treadmill), treadmill walking combined with anodal tDCS (AtDCS+treadmill) delivered over the motor cortex, and treadmill walking combined with sham stimulation (StDCS+treadmill)...
April 8, 2017: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/28396090/executive-summary-of-imported-infectious-diseases-after-returning-from-foreign-travel-consensus-document-of-the-spanish-society-for-infectious-diseases-and-clinical-microbiology-seimc
#16
José Luis Pérez-Arellano, Miguel Górgolas-Hernández-Mora, Fernando Salvador, Cristina Carranza-Rodríguez, Germán Ramírez-Olivencia, Esteban Martín-Echeverría, Azucena Rodríguez-Guardado, Francesca Norman, Virginia Velasco-Tirado, Zuriñe Zubero-Sulibarría, Gerardo Rojo-Marcos, José Muñoz-Gutierrez, José Manuel Ramos-Rincón, M Paz Sánchez-Seco-Fariñas, María Velasco-Arribas, Moncef Belhassen-García, Mar Lago-Nuñez, Elías Cañas García-Otero, Rogelio López-Vélez
In a global world, knowledge of imported infectious diseases is essential in daily practice, both for the microbiologist-parasitologist and the clinician who diagnoses and treats infectious diseases in returned travelers. Tropical and subtropical countries where there is a greater risk of contracting an infectious disease are among the most frequently visited tourist destinations. The SEIMC considers it appropriate to produce a consensus document that will be useful to primary care physicians as well as specialists in internal medicine, infectious diseases and tropical medicine who help treat travelers returning from tropical and sub-tropical areas with infections...
April 7, 2017: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/28395369/antibiotics-prescriptions-in-the-neonatal-intensive-care-unit-how-to-overcome-everyday-challenges
#17
D Donà, E Mozzo, V Mardegan, U Trafojer, P Lago, S Salvadori, E Baraldi, C Giaquinto
Antimicrobial prescriptions in neonatal intensive care units (NICUs) represent a point of concern for the emergence of MDROs and for morbidity associated with prolonged antibiotic exposure (e.g., invasive candidiasis, necrotizing enterocolitis, and late-onset sepsis). Antimicrobial stewardship programs (ASPs) have shown to be a valuable tool for the prevention of resistance with the goals of optimizing clinical outcomes while decreasing unnecessary prescribing. The most frequent ASP strategies include the correct collection and interpretation of microbiological specimens, prescription of the narrowest-spectrum antibiotic appropriate for a particular case, and de-escalation or discontinuation of therapy in defined situations...
April 10, 2017: American Journal of Perinatology
https://www.readbyqxmd.com/read/28395361/terpenoids-from-leaves-of-guarea-macrophylla-display-in-vitro-cytotoxic-activity-and-induce-apoptosis-in-melanoma-cells
#18
Geanne Alexandra A Conserva, Natalia Girola, Carlos R Figueiredo, Ricardo A Azevedo, Sasha Mousdell, Patricia Sartorelli, Marisi G Soares, Guilherme M Antar, João Henrique G Lago
Guarea macrophylla is a Brazilian plant species that has been used in folk medicine to treat a range of diseases. Our ongoing work focuses on the discovery of new bioactive natural products derived from Brazilian flora. The current study describes the identification of cytotoxic compounds from the EtOH extract of leaves from G. macrophylla using bioactivity-guided fractionation. This approach resulted in the isolation and characterization of four compounds: cycloart-23E-ene-3β,25-diol (1), (23S*,24S*)-dihydroxycicloart-25-en-3-one (2), isopimara-7,15-diene-2α,3β-diol (3), and isopimara-7,15-dien-3β-ol (4), in which 2 and 3 are identified as new derivatives...
April 10, 2017: Planta Medica
https://www.readbyqxmd.com/read/28393946/a-theoretical-study-of-complexes-formed-between-cations-and-curved-aromatic-systems-electrostatics-does-not-always-control-cation-%C3%AF-interaction
#19
Jorge A Carrazana-García, Enrique M Cabaleiro-Lago, Jesús Rodríguez-Otero
The present work studies the interaction of two extended curved π-systems (corannulene and sumanene) with various cations (sodium, potassium, ammonium, tetramethylammonium, guanidinium and imidazolium). Polyatomic cations are models of groups found in important biomolecules in which cation-π interaction plays a fundamental role. The results indicate an important size effect: with extended π systems and cations of the size of potassium and larger, dispersion is much more important than has been generally recognized for cation-π interactions...
April 19, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28393542/examining-maternal-age-breastfeeding-self-efficacy-and-health-locus-of-control-in-psychological-wellbeing-of-mothers
#20
Abiodun Musbau Lawal, Erhabor Sunday Idemudia
We investigated the direct and interaction influence of maternal age, breastfeeding self-efficacy (BSE), health locus of control (HLOC) on six dimensions of psychological wellbeing of breastfeeding mothers in Lagos, Nigeria. Data were collected from a convenience sample of 291 mothers attending health facilities in two suburb local government areas. The survey included socio-demographics (maternal age, marital status, ethnicity, education level and position of the baby currently breastfeeding), breastfeeding self-efficacy, health locus of control and psychological wellbeing scales...
April 9, 2017: Psychology, Health & Medicine
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