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https://www.readbyqxmd.com/read/28538919/expert-communities-and-interest-formation-in-the-brazilian-aids-program
#1
Regina Ferro do Lago, Nilson do Rosário Costa
This paper examines the role of the Technical Advisory Committee for antiretroviral therapy of the Brazilian AIDS program in mediating the decision-making process of including new antiretroviral (ARV) drugs in the Unified Health System services by the end of the 2000s. We conducted documental analysis and interviews with key informants from the governmental sphere and professionals. The work features the Technical Advisory Committee as an "expert community", defined as a network of individuals with expertise and competence in a particular sphere and whose knowledge is relevant in critical public policy decision areas...
May 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28532622/solid-waste-generation-and-characterization-in-the-university-of-lagos-for-a-sustainable-waste-management
#2
A E Adeniran, A T Nubi, A O Adelopo
Waste characterization is the first step to any successful waste management policy. In this paper, the characterization and the trend of solid waste generated in University of Lagos, Nigeria was carried out using ASTM D5231-92 and Resource Conservation Reservation Authority RCRA Waste Sampling Draft Technical Guidance methods. The recyclable potential of the waste is very high constituting about 75% of the total waste generated. The estimated average daily solid waste generation in Unilag Akoka campus was estimated to be 32...
May 19, 2017: Waste Management
https://www.readbyqxmd.com/read/28530605/screening-of-passiflora-l-mineral-content-using-principal-component-analysis-and-kohonen-self-organizing-maps
#3
Cleber Galvão Novaes, Ivana Lago da Silva Romão, Berlane Gomes Santos, Jéssica Palhares Ribeiro, Marcos Almeida Bezerra, Erik Galvão Paranhos da Silva
A method using digestion with diluted nitric acid and inductively coupled plasma optical emission spectrometry was applied to determine metal ions in the peel, pulp, and seed of Passiflora edulis f. flavicarpa and Passiflora cincinnata cultivated in the Bahia state, Brazil. Plasma parameters (radio frequency power and argon flow rates) were optimized. The quantification limits (µg g(-1)) were: Ca (43.0); Co (1.3); Cu (10.0); Fe (10.0); K (20.0); Mg (26.6); Mn (0.33); Na (56.6) and Zn (10.0). The accuracy of the method was evaluated by the analysis of certified reference materials (NIST 1567a Wheat Flour and NIST 1577b Bovine Liver)...
October 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28527828/buffer-formulation-affects-the-interaction-between-lysozyme-and-polymeric-nanoparticles
#4
Martin Lundqvist, Celia Cabaleiro-Lago
The effect of the buffer formulation in terms of buffer identity and ionic strength on the interaction between chicken egg lysozyme and carboxyl-modified polystyrene nanoparticles has been systematically studied. The time evolution of the fluorescence of a reporter molecule shows that lysozyme interacts with the nanoparticles in all the studied conditions. The interaction results in changes in protein conformation and decrease of the colloidal stability of nanoparticles. In absence of a background salt the rate of adsorption is affected mainly by the ionic strength of the buffer solution, although, specific buffer effects may contribute to a certain extent...
May 12, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28527287/-identification-of-the-mycobacterium-tuberculosis-beijing-lineage-in-ecuador
#5
Patricia Jiménez, Karina Calvopiña, Diana Herrera, Carlos Rojas, Laura Pérez-Lago, Marcelo Grijalva, Remedios Guna, Darío García-de Viedma
INTRODUCTION: Mycobacterium tuberculosis Beijing lineage isolates are considered to be especially virulent, transmissible and prone to acquire resistances. Beijing strains have been reported worldwide, but studies in Latin America are still scarce. The only multinational study performed in the region indicated a heterogeneous distribution for this lineage, which was absent in Chile, Colombia and Ecuador, although further studies found the lineage in Chile and Colombia. OBJECTIVE: To search for the presence of the Beijing lineage in Ecuador, the only country in the region where it remains unreported...
June 1, 2017: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/28526543/thyroid-hormone-biosynthesis-machinery-is-altered-in-the-ischemic-myocardium-an-epigenomic-study
#6
Carolina Gil-Cayuela, Esther Roselló-LLetí, Estefanía Tarazón, Ana Ortega, Juan Sandoval, Luis Martínez-Dolz, Juan Cinca, Esther Jorge, José Ramón González-Juanatey, Francisca Lago, Miguel Rivera, Manuel Portolés
BACKGROUND: Abnormal thyroid hormone (TH) metabolism is significantly associated with impaired left ventricular (LV) function and death. Although TH was traditionally thought to be produced exclusively by the thyroid gland, an increasing number of studies report TH production in other tissues. Based on these findings, we evaluated whether the genes required for TH biosynthesis are expressed in the human heart, and whether their expression is altered in patients with ischemic cardiomyopathy (ICM) and is related to epigenetic variations...
May 11, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28525320/sexual-and-reproductive-health-priorities-of-adolescent-girls-in-lagos-nigeria-findings-from-free-listing-interviews
#7
Juliet Iwelunmor, Sarah Blackstone, Ucheoma Nwaozuru, Donaldson Conserve, Patricia Iwelunmor, John E Ehiri
Background Adolescent girls in Nigeria experience a disproportionately high burden of sexual and reproductive health disparities that affect their well-being. Yet, little is known about adolescent girls' own unique perspectives of the sexual and reproductive health challenges they face, and possible solutions to these challenges. Aims To explore top sexual and reproductive health concerns of female adolescents in Nigeria and their perceptions regarding potential solutions to these issues. Methods Eighty adolescent girls attending two public secondary schools in Lagos, Nigeria completed individual free-listing interviews...
May 17, 2017: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/28522802/proteome-remodelling-by-the-stress-sigma-factor-rpos-%C3%AF-s-in-salmonella-identification-of-small-proteins-and-evidence-for-post-transcriptional-regulation
#8
Magali Lago, Véronique Monteil, Thibaut Douche, Julien Guglielmini, Alexis Criscuolo, Corinne Maufrais, Mariette Matondo, Françoise Norel
The RpoS/σ(S) sigma subunit of RNA polymerase is the master regulator of the general stress response in many Gram-negative bacteria. Extensive studies have been conducted on σ(S)-regulated gene expression at the transcriptional level. In contrast, very limited information regarding the impact of σ(S) on global protein production is available. In this study, we used a mass spectrometry-based proteomics approach to explore the wide σ(S)-dependent proteome of the human pathogen Salmonella enterica serovar Typhimurium...
May 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28516142/survey-data-on-factors-affecting-negotiation-of-professional-fees-between-estate-valuers-and-their-clients-when-the-mortgage-is-financed-by-bank-loan-a-case-study-of-mortgage-valuations-in-ikeja-lagos-state-nigeria
#9
Chukwuemeka O Iroham, Hilary I Okagbue, Olalekan A Ogunkoya, James D Owolabi
In this article, two sets of questionnaires were administered to professionals and clients (commercial banks) on their willingness to negotiate the professional fees charged by the Estate Valuers assuming that the mortgage in valuation was financed by bank loan. A range of fees options were provided. Other factors such as the business environment and mortgage valuation can influence the negotiated fees when the data obtained from the survey data is analyzed.
June 2017: Data in Brief
https://www.readbyqxmd.com/read/28513507/early-pregnancy-plasminogen-activator-inhibitor-1-levels-in-nigerian-women-and-its-relationship-with-preeclampsia
#10
I C Udenze, A P Arikawe, C C Makwe
AIM: This study compared early plasma levels of plasminogen activator inhibitor-1 (PAI-1) in normal pregnancy and preeclampsia and determined its relationship with disease severity. SUBJECTS AND METHODS: This was a prospective cohort study of 195 normotensive, aproteinuric pregnant women without prior history of gestational hypertension. The women were attending the Antenatal Clinic at The Lagos University Teaching Hospital and were within 24 weeks gestation at recruitment...
May 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28511895/diagnostic-performance-of-anyplex-ii-mtb-mdr-xdr-for-detection-of-resistance-to-first-and-second-line-drugs-in-mycobacterium-tuberculosis
#11
F Pérez-García, M J Ruiz-Serrano, P López Roa, Fermín Acosta, Laura Pérez-Lago, D García-De-Viedma, E Bouza
PURPOSE: Genotypic methods have considerably improved the diagnosis of multidrug-resistant (MDR) tuberculosis. One of these tests is Anyplex II MTB/MDR/XDR (Anyplex). Our aim was to evaluate the diagnostic performance of this multiplex PCR. METHODS: We conducted our study on 47 MDR tuberculosis and 14 pan-susceptible strains. We evaluated the ability of Anyplex to detect resistance mutations in rpoB (rifampin [RIF]), katG and inhA (isoniazid [INH]), gyrA (fluoroquinolones [FLQ]), and rrs and eis (aminoglycosides [AMG])...
May 13, 2017: Journal of Microbiological Methods
https://www.readbyqxmd.com/read/28507612/pattern-of-injuries-in-fatal-motorcycle-accidents-seen-in-lagos-state-university-teaching-hospital-an-autopsy-based-study
#12
Francis Faduyile, Festus Emiogun, Sunday Soyemi, Olugbenga Oyewole, Uche Okeke, Oluseun Williams
BACKGROUND: Deaths from motorcycle accident injuries have remained a major public health issue in Nigeria over the years. AIM: The study is to determine the age and gender distribution of the victims and to identify the cause of death and the anatomical pattern of injuries seen. METHODOLOGY: This is a 5-year autopsy-based study of all motorcycle accident deaths seen in Lagos State University Teaching Hospital between December 2009 and November 2014...
April 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28503348/emerging-trends-in-the-epidemiological-pattern-of-head-and-neck-cancers-in-lagos-nigeria
#13
O A Erinoso, E Okoturo, O M Gbotolorun, O A Effiom, N A Awolola, S S Soyemi, R T Oluwakuyide
BACKGROUND: Unfortunately, despite an increase in medical knowledge, survival rates of head and neck cancers (HNCs) have not been observed to improve greatly. This is true, especially in tumors located in obscure primary sites or late presentation. AIM: The purpose of this study is to assess the epidemiologic pattern of HNCs and to evaluate its emerging trends and patterns in Lagos state. SUBJECTS AND METHODS: A retrospective study was conducted from 2003 to 2013 that analyzed histologically diagnosed cases of HNC at the Pathology Departments of the two tertiary teaching hospitals in Lagos...
September 2016: Annals of Medical and Health Sciences Research
https://www.readbyqxmd.com/read/28501598/microgramma-vacciniifolia-polypodiaceae-fronds-contain-a-multifunctional-lectin-with-immunomodulatory-properties-on-human-cells
#14
Leydianne Leite de Siqueira Patriota, Thamara Figueiredo Procópio, Jéssica de Santana Brito, Virginie Sebag, Ana Patrícia Silva de Oliveira, Ana Karine de Araújo Soares, Leyllane Rafael Moreira, Thâmarah de Albuquerque Lima, Tatiana Soares, Túlio Diego da Silva, Patrícia Maria Guedes Paiva, Virgínia Maria Barros de Lorena, Cristiane Moutinho Lagos de Melo, Lidiane Pereira de Albuquerque, Thiago Henrique Napoleão
In this study, we report the purification and characterization of a multifunctional lectin (MvFL) from Microgramma vacciniifolia fronds as well as its immunomodulatory properties on human peripheral blood mononuclear cells (PBMCs). MvFL (pI 4.51; 54kDa) is a glycoprotein able to inhibit trypsin activity and that has sequence similarities (32% coverage) with a plant RNA-binding protein. Hemagglutinating activity of MvFL was not altered by heating at 100°C for 30min, but was reduced in alkaline pH (8.0 and 9...
May 10, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28501214/capillary-electrophoresis-tandem-mass-spectrometry-determination-of-glutamic-acid-and-homocysteine-s-metabolites-potential-biomarkers-of-amyotrophic-lateral-sclerosis
#15
Zuzana Cieslarova, Fernando Silva Lopes, Claudimir Lucio do Lago, Marcondes Cavalcante França, Ana Valéria Colnaghi Simionato
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that affects both lower and upper motor neurons, leading to muscle atrophy, paralysis, and death caused by respiratory failure or infectious complications. Altered levels of homocysteine, cysteine, methionine, and glutamic acid have been observed in plasma of ALS patients. In this context, a method for determination of these potential biomarkers in plasma by capillary electrophoresis tandem mass spectrometry (CE-MS/MS) is proposed herein. Sample preparation was carefully investigated, since sulfur-containing amino acids may interact with plasma proteins...
August 1, 2017: Talanta
https://www.readbyqxmd.com/read/28495460/dual-energy-computed-tomography-for-the-detection-of-focal-liver-lesions
#16
K N Lago, J Vallejos, C Capuñay, E Salas, E Reynoso, J B Carpio, P M Carrascosa
OBJECTIVE: To qualitatively and quantitatively explore the spectral study of focal liver lesions, comparing it with the usual polychromatic assessment with single-energy computed tomography. MATERIAL AND METHODS: We prospectively studied 50 patients with at least one focal liver lesion who were referred for abdominal multidetector computed tomography with intravenous contrast material. The portal phase was acquired with dual energy sources. The density of the lesions and of the surrounding liver parenchyma was measured both in the baseline polychromatic acquisition and in the posterior monochromatic reconstructions at 40 keV, 70 keV, and 140 keV...
May 8, 2017: Radiología
https://www.readbyqxmd.com/read/28492791/respiratory-muscle-training-improves-diaphragm-citrate-synthase-activity-and-hemodynamic-function-in-rats-with-heart-failure
#17
Rodrigo Boemo Jaenisch, Mariane Bertagnolli, Audrey Borghi-Silva, Ross Arena, Pedro Dal Lago
INTRODUCTION: Enhanced respiratory muscle strength in patients with heart failure positively alters the clinical trajectory of heart failure. In an experimental model, respiratory muscle training in rats with heart failure has been shown to improve cardiopulmonary function through mechanisms yet to be entirely elucidated. OBJECTIVE: The present report aimed to evaluate the respiratory muscle training effects in diaphragm citrate synthase activity and hemodynamic function in rats with heart failure...
March 2017: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28492208/self-reported-dental-pain-and-dental-caries-among-8-12-year-old-school-children-an-exploratory-survey-in-lagos-nigeria
#18
Abiola A Adeniyi, Olumuyiwa O Odusanya
BACKGROUND: Dental pain is considered an important public health problem because it affects the daily life of children. This study was designed to assess the prevalence, associated factors, and impact of dental pain among 8-12-year-old school children in Lagos, Nigeria. SUBJECTS AND METHODS: A cross-sectional survey to determine self-reported dental pain among 8-12-year-old school children using an interviewer-administered questionnaire was conducted. This was followed by a clinical examination to determine the child's oral hygiene status and dental caries status...
January 2017: Nigerian Postgraduate Medical Journal
https://www.readbyqxmd.com/read/28489890/unmasking-inequalities-sub-national-maternal-and-child-mortality-data-from-two-urban-slums-in-lagos-nigeria-tells-the-story
#19
Erin Anastasi, Ekanem Ekanem, Olivia Hill, Agnes Adebayo Oluwakemi, Oluwatosin Abayomi, Andrea Bernasconi
INTRODUCTION: Nigeria has one of the highest maternal mortality ratios in the world as well as high perinatal mortality. Unfortunately, the country does not have the resources to assess this critical indicator with the conventional health information system and measuring its progress toward the goal of ending preventable maternal deaths is almost impossible. Médecins Sans Frontières (MSF) conducted a cross-sectional study to assess maternal and perinatal mortality in Makoko Riverine and Badia East, two of the most vulnerable slums of Lagos...
2017: PloS One
https://www.readbyqxmd.com/read/28487212/mapping-the-ecoepidemiology-of-zika-virus-infection-in-urban-and-rural-areas-of-pereira-risaralda-colombia-2015-2016-implications-for-public-health-and-travel-medicine
#20
Alfonso J Rodriguez-Morales, Pablo Ruiz, Javier Tabares, Carlos Augusto Ossa, Maria Camila Yepes-Echeverry, Valeria Ramirez-Jaramillo, Maria Leonor Galindo-Marquez, Carlos Julian García-Loaiza, Juan Alejandro Sabogal-Roman, Esteban Parra-Valencia, Guillermo J Lagos-Grisales, Carlos O Lozada-Riascos, Cornelis A de Pijper, Martin P Grobusch
OBJECTIVE: Geographical information systems (GIS) have been demonstrated earlier to be of great use to inform public health action against vector-borne infectious diseases. METHODS: Using surveillance data on the ongoing ZIKV outbreak from Pereira, Colombia (2015-2016), we estimated incidence rates (cases/100,000 population), and developed maps correlating with the ecoepidemiology of the area. RESULTS: Up to October 8, 2016, 439 cases of ZIKV were reported in Pereira (93 cases/100,000 pop...
May 6, 2017: Travel Medicine and Infectious Disease
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