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https://www.readbyqxmd.com/read/28814377/body-weight-misperception-and-dissatisfaction-among-overweight-and-obese-adult-nigerians
#1
Mukadas Oyeniran Akindele, Joliana Phillips, Ehimario Igumbor, Ushotanefe Useh
BACKGROUND: The increase in the prevalence of overweight and obesity in low- and medium-income countries has a negative impact on overall health. Correct perception of one's body weight is a step in seeking healthy help toward weight reduction in overweight and obese individuals. OBJECTIVE: This study was carried out to assess the body weight misperception and dissatisfaction among overweight and obese adults in an urban African setting. METHODS: This study was part of a larger cross-sectional study that was designed to plan an intervention for overweight and obese adults in an urban African setting...
August 16, 2017: JMIR Public Health and Surveillance
https://www.readbyqxmd.com/read/28812677/species-specific-responses-to-ocean-acidification-should-account-for-local-adaptation-and-adaptive-plasticity
#2
Cristian A Vargas, Nelson A Lagos, Marco A Lardies, Cristian Duarte, Patricio H Manríquez, Victor M Aguilera, Bernardo Broitman, Steve Widdicombe, Sam Dupont
Global stressors, such as ocean acidification, constitute a rapidly emerging and significant problem for marine organisms, ecosystem functioning and services. The coastal ecosystems of the Humboldt Current System (HCS) off Chile harbour a broad physical-chemical latitudinal and temporal gradient with considerable patchiness in local oceanographic conditions. This heterogeneity may, in turn, modulate the specific tolerances of organisms to climate stress in species with populations distributed along this environmental gradient...
March 13, 2017: Nature ecology & evolution
https://www.readbyqxmd.com/read/28810516/lectin-from-inflorescences-of-ornamental-crop-alpinia-purpurata-acts-on-immune-cells-to-promote-th1-and-th17-responses-nitric-oxide-release-and-lymphocyte-activation
#3
Jéssica de Santana Brito, Gustavo Ramos Salles Ferreira, Emeline Klimczak, Liliya Gryshuk, Nataly Diniz de Lima Santos, Leydianne Leite de Siqueira Patriota, Leyllane Rafael Moreira, Ana Karine Araújo Soares, Bruno Rafael Barboza, Patrícia Maria Guedes Paiva, Daniela Maria do Amaral Ferraz Navarro, Virgínia Maria Barros de Lorena, Cristiane Moutinho Lagos de Melo, Marília Cavalcanti Coriolano, Thiago Henrique Napoleão
Alpinia purpurata is an ornamental crop known as a source of bioactive molecules. This is the first study to report isolation of a lectin (carbohydrate-binding protein) from A. purpurata inflorescences (ApuL). The immunomodulatory potential of ApuL was evaluated by investigating its effects on the production of cytokines and release of nitric oxide by human peripheral blood mononuclear cells (PBMCs). In addition, the differentiation and activation of lymphocytes treated with ApuL was evaluated by immunophenotyping assays...
August 10, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28807132/primary-health-care-workers-knowledge-and-attitudes-towards-depression-and-its-management-in-the-mehpric-p-project-lagos-nigeria
#4
Abiodun O Adewuya, Tomilola Adewumi, Bolanle Ola, Olayinka Abosede, Abiodun Oyeneyin, Adedolapo Fasawe, Olajide Idris
OBJECTIVE: This study aimed to evaluate the knowledge, perceived challenges and attitude of primary health care (PHC) workers in Lagos to depression and its management in the PHC. METHODS: Health workers (n=607) from 49 "flagship" PHCs in Lagos were evaluated for their level of knowledge, experience, competence, attitude and perceived challenges to managing depression in the primary care using a case vignette. RESULTS: More than half (56.2%) of the health workers correctly diagnosed depression...
July 2017: General Hospital Psychiatry
https://www.readbyqxmd.com/read/28806412/missed-opportunities-for-hiv-control-gaps-in-hiv-testing-for-partners-of-people-living-with-hiv-in-lima-peru
#5
Ana L Vasquez, Renato A Errea, Daniel Hoces, Juan Echevarria, Elsa González-Lagos, Eduardo Gotuzzo
INTRODUCTION: Based on the hypothesis that HIV programs struggle to deliver health services that harmonize necessities of treatment and prevention, we described the outcomes of routinely provided HIV testing to partners of people living with HIV (PLWH) through a secondary analysis of routine data collected at a public hospital in Lima, Peru. METHODS: Among PLWH enrolled in the study center's HIV program between 2005 and 2014, we identified index cases (IC): PLWH who reported a unique partner not previously enrolled...
2017: PloS One
https://www.readbyqxmd.com/read/28798893/complementary-feeding-knowledge-practices-and-dietary-diversity-among-mothers-of-under-five-children-in-an-urban-community-in-lagos-state-nigeria
#6
Foluke Adenike Olatona, Jesupelumi Oreoluwa Adenihun, Sunday Adedeji Aderibigbe, Oluwafunmilayo Funke Adeniyi
BACKGROUND AND OBJECTIVES: Inappropriate complementary feeding is a major cause of child malnutrition and death. This study determined the complementary feeding knowledge, practices, minimum dietary diversity, and acceptable diet among mothers of under-five children in an urban Local Government Area of Lagos State, Southwest Nigeria. METHODS: This descriptive cross-sectional study was conducted in Eti-Osa area of Lagos State, Nigeria. Multi-stage sampling technique was employed to select 355 mothers and infants...
2017: International Journal of MCH and AIDS
https://www.readbyqxmd.com/read/28797881/synthesis-and-structure-activity-relationship-study-of-novel-3-heteroarylcoumarins-based-on-pyridazine-scaffold-as-selective-mao-b-inhibitors
#7
María Carmen Costas-Lago, Pedro Besada, Fernanda Rodríguez-Enríquez, Dolores Viña, Santiago Vilar, Eugenio Uriarte, Fernanda Borges, Carmen Terán
Compounds of hybrid structure pyridazine-coumarin were discovered as potent, selective and reversible inhibitors of monoamine oxidase B (MAO-B). These compounds were synthesized in good yield following a multistep approach based on Knoevenagel reaction and using as key intermediate pyridazinone 16, which was obtained from maleic anhydride and furan. Compounds 9b and 9d are the most active compounds of these series, with IC50 values in the sub-micromolar range, and lack of cytotoxic effects. Theoretical calculation of ADME properties also suggested a good pharmacokinetic profile for both compounds...
July 25, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28795095/quantitative-exploration-of-factors-influencing-psychotic-disorder-ailments-in-nigeria
#8
Adebowale O Adejumo, Nehemiah A Ikoba, Esivue A Suleiman, Hilary I Okagbue, Pelumi E Oguntunde, Oluwole A Odetunmibi, Obalowu Job
In this data article, records on demographic data, family problem issues, as well as results of medical tests from five major classes of psychotic disorder namely: bipolar; vascular dementia, minimal brain dysfunction; insomnia; and schizophrenia, were collected on 500 psychotic patients carefully selected from the pool of medical records of Yaba Psychiatric Hospital, Lagos, Nigeria, for the period of 5 years, between January 2010 and December 2014, were examined. X-squared Statistic was used to examine each of psychotic disorders to identify demographic (age, gender, religion, marital status, and occupation) and family issues (loss of parent, history of such ailment in the family (family status), divorce, head injury, and heredity of such ailment (genetic) factors that influence them...
October 2017: Data in Brief
https://www.readbyqxmd.com/read/28780580/net-atrioventricular-compliance-is-an-independent-predictor-of-cardiovascular-death-in-mitral-stenosis
#9
Maria Carmo Pereira Nunes, Timothy C Tan, Sammy Elmariah, Lucas Lodi-Junqueira, Bruno Ramos Nascimento, Rodrigo do Lago, Jose Luiz Padilha da Silva, Rodrigo Citton Padilha Reis, Xin Zeng, Igor F Palacios, Judy Hung, Robert A Levine
OBJECTIVES: Rheumatic mitral stenosis (MS) is a progressive disease, and risk of death may persist despite relief of the obstruction. Net atrioventricular compliance (Cn) modulates the overall haemodynamic burden of the MS and may be useful in predicting cardiovascular death after percutaneous mitral valvuloplasty (PMV). METHODS: A total of 427 patients (mean age 50±16 years, 84% female) with severe MS undergoing PMV were enrolled. Doppler-derived Cn was estimated at baseline using a previously validated equation...
August 5, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28779952/tuning-the-surface-properties-of-biochar-by-thermal-treatment
#10
Fernanda Gomes de Mendonça, Igor Tadeu da Cunha, Ricardo Reis Soares, Juliana Cristina Tristão, Rochel Montero Lago
In this work, the effect of controlled thermal treatment to tune biochar surface properties such as area/porosity, functionalities and reactivity was investigated. TG-MS, CHN, Raman, IR, BET, Zeta and SEM analyses suggested that thermal treatment led to the decomposition of an organic complex/amorphous phase to produce micropores based on graphene nanostructures and a strong increase on surface area from 3m(2)g(-1) for biochar to 30, 408 and 590m(2)g(-1), at 400, 600 and 800°C, respectively. The treatment also led to a gradual decrease on oxygen content from 27 to 14wt% at 800°C due to decomposition of surface functionalities changing surface properties such as zeta potential, adsorption of anionic and cationic species and an increase on the activity for sulfide oxidation which is discussed in terms of increase in surface area and the presence of surface redox quinone groups...
July 24, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28774184/circadian-variation-and-in-vitro-cytotoxic-activity-evaluation-of-volatile-compounds-from-leaves-of-piper-regnellii-miq-c-dc-var-regnellii-c-dc-yunck-piperaceae
#11
Roseli R Anderson, Natalia Girola, Carlos R Figueiredo, Vinicius S Londero, João Henrique G Lago
Aiming detection of circadian variation in the chemical composition of volatiles from Piper regnellii, the leaves were collected during four different periods (8, 12, 16 and 20 h) in the same day. After extraction by hydrodistillation and GC/MS analysis, no significant variation was observed for the main compounds: germacrene D (45.6 ± 1.5-51.4 ± 3.1%), α-chamigrene (8.9 ± 1.3-11.3 ± 2.7%) and β-caryophyllene (8.2 ± 0.9-9.5 ± 0.3%). Evaluation of in vitro cytotoxicity against several cancer and non-tumourigenic cells indicated promising activity, especially to HeLa (human cervical carcinoma) with IC50 ranging from 11 ± 3 to 17 ± 3 μg/mL...
August 3, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28769998/a-monte-carlo-study-of-the-photon-spectrum-due-to-the-different-materials-used-in-the-construction-of-flattening-filters-of-linac
#12
J S Estepa Jiménez, M Díaz Lagos, S A Martinez-Ovalle
Different types the spectrum of photons were studied; they were emitted from the flattening filter of a LINAC Varian 2100 C/D that operates at 15 MV. The simplified geometry of the LINAC head was calculated using the MCNPX code based on the studies of the materials of the flattening filter, namely, SST, W, Pb, Fe, Ta, Al, and Cu. These materials were replaced in the flattening filter to calculate the photon spectra at the output of this device to obtain the spectrum that makes an impact with the patient. The different spectra obtained were analyzed and compared to the emission from the original spectra configuration of the LINAC, which uses material W...
2017: Computational and Mathematical Methods in Medicine
https://www.readbyqxmd.com/read/28762683/-gross-hematuria-after-kidney-biopsy-a-case-report
#13
Rocco Manganelli, Salvatore Iannaccone, Giulio Lombardi, Michele De Siero, Lucia Lago, Giuseppe Desiderio, Emanuele De Simone, Michelangelo Viscione, Carmine Tirri
We describe the clinical case of a patient experiencing severe gross hematuria causing clotting in the renal pelvis, after undergoing a kidney biopsy.The ecocolordopper and CT angiography performed did not reveal the cause of hematuria.The kidney arteriography allowed the diagnosis, revealing an arteriovenous fistula responsible for bleeding together with a small false aneurysm in the lower pole of the biopsied kidney. Both lesions were successfully treated with superselective embolization with microcoils. We discuss about the diagnostic and therapeutic approach of these rare post-biopsy complications briefly focusing on the technical aspects and on possible risks that the transcatheter embolotherapy may result...
August 1, 2017: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://www.readbyqxmd.com/read/28761071/phosphopredict-a-bioinformatics-tool-for-prediction-of-human-kinase-specific-phosphorylation-substrates-and-sites-by-integrating-heterogeneous-feature-selection
#14
Jiangning Song, Huilin Wang, Jiawei Wang, André Leier, Tatiana Marquez-Lago, Bingjiao Yang, Ziding Zhang, Tatsuya Akutsu, Geoffrey I Webb, Roger J Daly
Protein phosphorylation is a major form of post-translational modification (PTM) that regulates diverse cellular processes. In silico methods for phosphorylation site prediction can provide a useful and complementary strategy for complete phosphoproteome annotation. Here, we present a novel bioinformatics tool, PhosphoPredict, that combines protein sequence and functional features to predict kinase-specific substrates and their associated phosphorylation sites for 12 human kinases and kinase families, including ATM, CDKs, GSK-3, MAPKs, PKA, PKB, PKC, and SRC...
July 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28752943/correlations-between-psychopathology-and-self-reported-quality-of-life-among-adolescents-in-youth-correctional-facilities-in-lagos-nigeria-a-short-report
#15
Olayinka Atilola, Bolanle Ola, Gbonjubola Abiri, Abiodun O Adewuya
BACKGROUND: The relationship between psychopathology and quality of life (QoL) and well-being among young incarcerated offenders has hardly been explored. AIMS: Our aim was to test the hypothesis that higher self-rated psychopathology would be associated with lower QoL among adolescents resident within youth correctional facilities in Lagos. METHODS: Psychopathology was assessed using the Strength and Difficulty Questionnaire (SDQ), while QoL was measured by using the Paediatric Quality of Life...
July 28, 2017: Criminal Behaviour and Mental Health: CBMH
https://www.readbyqxmd.com/read/28751930/the-correlation-between-chemical-structures-and-antioxidant-prooxidant-and-antitrypanosomatid-properties-of-flavonoids
#16
João Luiz Baldim, Bianca Gonçalves Vasconcelos de Alcântara, Olívia da Silva Domingos, Marisi Gomes Soares, Ivo Santana Caldas, Rômulo Dias Novaes, Tiago Branquinho Oliveira, João Henrique Ghilardi Lago, Daniela Aparecida Chagas-Paula
Flavonoids have demonstrated in vivo and in vitro leishmanicidal, trypanocidal, antioxidant, and prooxidant properties. The chemotherapy of trypanosomiasis and leishmaniasis lacks efficacy, presents high toxicity, and is related to the development of drug resistance. Thus, a series of 40 flavonoids were investigated with the purpose of correlating these properties via structure and activity analyses based on integrated networks and QSAR models. The classical groups for the antioxidant activity of flavonoids were combined in order to explain the influence of antioxidant and prooxidant activities on the antiparasitic properties...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/28750934/serca2a-a-potential-non-invasive-biomarker-of-cardiac-allograft-rejection
#17
Estefanía Tarazón, Ana Ortega, Carolina Gil-Cayuela, Elena Sánchez-Lacuesta, Pilar Marín, Francisca Lago, José Ramón González-Juanatey, Luis Martínez-Dolz, Manuel Portolés, Miguel Rivera, Esther Roselló-Lletí
BACKGROUND: The detection of heart transplant rejection by non-invasive methods remains a major challenge. Despite the well-known importance of the study of sarcoplasmic reticulum Ca(2+)-ATPase (SERCA2a) in the heart, its role as a rejection marker has never been analyzed. Our objective in this study was to determine whether circulating SERCA2a could be a good marker of cardiac rejection. METHODS: We collected 127 consecutive endomyocardial biopsies (EMBs) and serum samples from adult heart transplant recipients (49 without allograft rejection and 78 with the diagnosis of biopsy allograft rejection, including 48 Grade 1R, 21 Grade 2R and 9 Grade 3R)...
July 5, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/28750806/new-methods-for-the-synthesis-of-cannabidiol-derivatives
#18
Ana Lago-Fernandez, Vanessa Redondo, Laura Hernandez-Folgado, Laura Figuerola-Asencio, Nadine Jagerovic
Cannabidiol (CBD) is one of the most abundant components isolated from Cannabis sativa. However, CBD is a nonpsychotropic phytocannabinoid. In the last decade, there has been a growing interest in its therapeutic effects. This is why this natural product represents a lead structure for the development of new cannabinoid compounds. Even though chemistry of CBD has been explored for more than 30 years, the synthesis of only a few derivatives has been described. This chapter first reviews the synthetic methods for the preparation of CBD and derivatives...
2017: Methods in Enzymology
https://www.readbyqxmd.com/read/28750597/a-maternal-high-fat-high-caloric-diet-delays-reflex-ontogeny-during-lactation-but-enhances-locomotor-performance-during-late-adolescence-in-rats
#19
Erika Vanesa Cadena-Burbano, Carolina Cadete Lucena Cavalcanti, Amanda Braz Lago, Raquel de Arruda Campos Benjamim, Thaynan Raquel Dos Prazeres Oliveira, Jacqueline Maria Silva, Raul Manhães-De-Castro, Raquel Da Silva Aragão
OBJECTIVE: The main goal of the present study was to investigate the effects of two maternal high-fat diets with different energy densities on the somatic growth, reflex ontogeny, and locomotor activity of offspring. METHODS: Twenty-nine female Wistar rats (220-250 g) were mated and grouped into three different dietary conditions: control (n = 11, AIN-93G diet, 3.6 kcal/g), high-fat/high-caloric (HH, n = 9, 51% of the calories from fat, 4.62 kcal/g), and high-fat/isocaloric (HI, n = 9, 51% of the calories from fat, 3...
July 28, 2017: Nutritional Neuroscience
https://www.readbyqxmd.com/read/28746517/ambiguity-of-care-in-the-experience-of-drug-consumers
#20
Edite Lago da Silva Sena, Mitze Lopes Araújo, Bárbara Santos Ribeiro, Vanessa Thamyris Carvalho Dos Santos, Sâmia de Carliris Barbosa Malhado, Carine de Jesus Soares, Patrícia Anjos Lima de Carvalho
Objective: To understand the perception of users of a Psychosocial Care Center about care in the context of drug use. Methods: Study based on the Phenomenology of Maurice Merleau-Ponty, developed in the Center for Psychosocial Care Alcohol and Other Drugs. The data has been submitted to the Analytical Technique of Ambiguity. Results: The drug use sometimes provides the consumer with pleasurable feelings, sometimes contributing to the occurrence of biopsychosocial harm and/or new possibilities for relationship with the drug...
July 20, 2017: Revista Gaúcha de Enfermagem
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