Ellen M Mowry, Robert A Bermel, James R Williams, Tammie L S Benzinger, Carl de Moor, Elizabeth Fisher, Carrie M Hersh, Megan H Hyland, Izlem Izbudak, Stephen E Jones, Bernd C Kieseier, Hagen H Kitzler, Lauren Krupp, Yvonne W Lui, Xavier Montalban, Robert T Naismith, Jacqueline A Nicholas, Fabio Pellegrini, Alex Rovira, Maximilian Schulze, Björn Tackenberg, Mar Tintore, Madalina E Tivarus, Tjalf Ziemssen, Richard A Rudick
Background: Multiple Sclerosis Partners Advancing Technology and Health Solutions (MS PATHS) is the first example of a learning health system in multiple sclerosis (MS). This paper describes the initial implementation of MS PATHS and initial patient characteristics. Methods: MS PATHS is an ongoing initiative conducted in 10 healthcare institutions in three countries, each contributing standardized information acquired during routine care. Institutional participation required the following: active MS patient census of ≥500, at least one Siemens 3T magnetic resonance imaging scanner, and willingness to standardize patient assessments, share standardized data for research, and offer universal enrolment to capture a representative sample...
2020: Frontiers in Neurology