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https://www.readbyqxmd.com/read/29786503/relationships-between-theoretically-derived-short-term-outcomes-and-support-for-policy-among-the-public-and-decision-makers
#1
Carol L Schmitt, Laurel Curry, Vanessa Boudewyns, Pamela A Williams, LaShawn Glasgow, Deanna Van Hersh, Jeffrey Willett, Todd Rogers
PURPOSE AND OBJECTIVES: Policy change is a lengthy and complex process. Thus, it is important to articulate hypothesized causal pathways between advocacy activities and policy change outcomes and to identify and monitor early indicators of progress toward policy change. INTERVENTION APPROACH: The Kansas Health Foundation supports grantee efforts to address the public health effects of obesity through evidence-based policy, systems, and environmental change interventions...
May 17, 2018: Preventing Chronic Disease
https://www.readbyqxmd.com/read/29786153/vasa-previa-screening-strategies-a-decision-and-cost-effectiveness-analysis
#2
R G Sinkey, A O Odibo
OBJECTIVE: The aim of this study is to perform a decision and cost-effectiveness analysis comparing four screening strategies for the antenatal diagnosis of vasa previa among singleton pregnancies. METHODS: A decision-analytic model was constructed comparing vasa previa screening strategies. Published probabilities and costs were applied to four transvaginal screening scenarios which occurred at the time of mid-trimester ultrasound: no screening, ultrasound-indicated screening, screening pregnancies conceived by in vitro fertilization (IVF), and universal screening...
May 22, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29786038/a-predictive-model-for-estimation-risk-of-proliferative-lupus-nephritis
#3
Dong-Ni Chen, Li Fan, Yu-Xi Wu, Qian Zhou, Wei Chen, Xue-Qing Yu
Background: Lupus nephritis (LN) is classified by renal biopsy into proliferative and nonproliferative forms, with distinct prognoses, but renal biopsy is not available for every LN patient. The present study aimed to establish an alternate tool by building a predictive model to evaluate the probability of proliferative LN. Methods: In this retrospective cohort with biopsy-proven LN, 382 patients in development cohort, 193 in internal validation cohort, and 164 newly diagnosed patients in external validation cohort were selected...
June 5, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29786019/measuring-situation-awareness-in-medical-education-objective-structured-clinical-examination-guides
#4
Margaret Frere, John Tepper, Markus Fischer, Kieran Kennedy, Thomas Kropmans
Background: Medical errors are among the most prevalent and serious adverse events in health care. Lack of situation awareness (SA) is an important factor leading to such errors. SA can be understood using Endsley's three-tier model: level 1 is perception, level 2 is comprehension, and level 3 is projection. While there is extensive literature on the theory of SA, it is difficult to measure and quantify. The purpose of this pilot study was to measure, identify, and characterize SA in some medical objective structured clinical examination (OSCE) guides, including a 1st year National University of Ireland, Galway (NUIG) OSCE...
September 2017: Education for Health: Change in Training & Practice
https://www.readbyqxmd.com/read/29785928/post-decision-biases-reveal-a-self-consistency-principle-in-perceptual-inference
#5
Long Luu, Alan A Stocker
Making a categorical judgment can systematically bias our subsequent perception of the world. We show that these biases are well explained by a self-consistent Bayesian observer whose perceptual inference process is causally conditioned on the preceding choice. We quantitatively validated the model and its key assumptions with a targeted set of three psychophysical experiments, focusing on a task sequence where subjects first had to make a categorical orientation judgment before estimating the actual orientation of a visual stimulus...
May 15, 2018: ELife
https://www.readbyqxmd.com/read/29785890/family-networks-and-healthy-behaviour-evidence-from-nepal
#6
Jolene Skordis, Noemi Pace, Marcos Vera-Hernandez, Imran Rasul, Emla Fitzsimons, David Osrin, Dharma Manandhar, Anthony Costello
Models of household decision-making commonly focus on nuclear family members as primary decision-makers. If extended families shape the objectives and constraints of households, then neglecting the role of this network may lead to an incomplete understanding of health-seeking behaviour. Understanding the decision-making processes behind care-seeking may improve behaviour change interventions, better intervention targeting and support health-related development goals. This paper uses data from a cluster randomised trial of a participatory learning and action cycle (PLA) through women's groups, to assess the role of extended family networks as a determinant of gains in health knowledge and health practice...
May 22, 2018: Health Economics, Policy, and Law
https://www.readbyqxmd.com/read/29785689/the-impact-of-hospital-costing-methods-on-cost-effectiveness-analysis-a-case-study
#7
José Leal, Stefania Manetti, James Buchanan
BACKGROUND: Several methods exist to cost hospital contacts when estimating the cost effectiveness of a new intervention. However, the implications of choosing a particular approach remain unclear. We compare the use of the three main diagnosis-related group (DRG)-based national unit costs in England to determine whether choice of approach can impact on economic evaluation results. METHODS: A cost-utility model was developed to compare secondary fracture prevention models of care for hip fracture patients, using data from large primary and hospital care administrative datasets in England...
May 22, 2018: PharmacoEconomics
https://www.readbyqxmd.com/read/29785493/mindset-and-communication-barriers-in-the-diffusion-of-bariatric-surgery
#8
REVIEW
Daniel Gero, Bors Hulesch, Marco Bueter
PURPOSE OF REVIEW: Cumulating evidence is available to demonstrate the efficacy of bariatric surgery (BS) in achieving weight loss and optimizing comorbidities. However, currently, only a minority of eligible patients approaches bariatric centers. The underuse of BS can no longer be explained by the lack of evidence supporting its beneficial outcomes along with its favorable safety-profile, rather, by the supporting infrastructure, insurance coverage, and mindset of society, including potential patients and allied healthcare professionals...
May 21, 2018: Current Atherosclerosis Reports
https://www.readbyqxmd.com/read/29785337/modelling-the-growth-of-the-brown-frog-rana-dybowskii
#9
Qing Tong, Xiao-Peng Du, Zong-Fu Hu, Li-Yong Cui, Hong-Bin Wang
Well-controlled development leads to uniform body size and a better growth rate; therefore, the ability to determine the growth rate of frogs and their period of sexual maturity is essential for producing healthy, high-quality descendant frogs. To establish a working model that can best predict the growth performance of frogs, the present study examined the growth of one-year-old and two-year-old brown frogs ( Rana dybowskii ) from metamorphosis to hibernation (18 weeks) and out-hibernation to hibernation (20 weeks) under the same environmental conditions...
2018: PeerJ
https://www.readbyqxmd.com/read/29785294/development-of-a-precision-multimodal-surgical-navigation-system-for-lung-robotic-segmentectomy
#10
Jean Marc Baste, Valentin Soldea, Samy Lachkar, Philippe Rinieri, Mathieu Sarsam, Benjamin Bottet, Christophe Peillon
Minimally invasive sublobar anatomical resection is becoming more and more popular to manage early lung lesions. Robotic-assisted thoracic surgery (RATS) is unique in comparison with other minimally invasive techniques. Indeed, RATS is able to better integrate multiple streams of information including advanced imaging techniques, in an immersive experience at the level of the robotic console. Our aim was to describe three-dimensional (3D) imaging throughout the surgical procedure from preoperative planning to intraoperative assistance and complementary investigations such as radial endobronchial ultrasound (R-EBUS) and virtual bronchoscopy for pleural dye marking...
April 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29785060/cost-effectiveness-of-vitamin-c-supplementation-for-pregnant-smokers-to-improve-offspring-lung-function-at-birth-and-reduce-childhood-wheeze-asthma
#11
Leah Yieh, Cindy T McEvoy, Scott W Hoffman, Aaron B Caughey, Kelvin D MacDonald, Dmitry Dukhovny
OBJECTIVE: To determine the implications of supplemental vitamin C for pregnant tobacco smokers and its effects on the prevalence of pediatric asthma, asthma-related mortality, and associated costs. STUDY DESIGN: A decision-analytic model built via TreeAge compared the outcome of asthma in a theoretical annual cohort of 480,000 children born to pregnant smokers through 18 years of life. Vitamin C supplementation (500 mg/day) with a standard prenatal vitamin was compared to a prenatal vitamin (60 mg/day)...
May 22, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29784905/northward-shift-of-the-agricultural-climate-zone-under-21-st-century-global-climate-change
#12
Myron King, Daniel Altdorff, Pengfei Li, Lakshman Galagedara, Joseph Holden, Adrian Unc
As agricultural regions are threatened by climate change, warming of high latitude regions and increasing food demands may lead to northward expansion of global agriculture. While socio-economic demands and edaphic conditions may govern the expansion, climate is a key limiting factor. Extant literature on future crop projections considers established agricultural regions and is mainly temperature based. We employed growing degree days (GDD), as the physiological link between temperature and crop growth, to assess the global northward shift of agricultural climate zones under 21st -century climate change...
May 21, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29784893/a-comparison-between-decision-tree-and-random-forest-in-determining-the-risk-factors-associated-with-type-2-diabetes
#13
Habibollah Esmaily, Maryam Tayefi, Hassan Doosti, Majid Ghayour-Mobarhan, Hossein Nezami, Alireza Amirabadizadeh
BACKGROUND: We aimed to identify the associated risk factors of type 2 diabetes mellitus (T2DM) using data mining approach, decision tree and random forest techniques using the Mashhad Stroke and Heart Atherosclerotic Disorders (MASHAD) Study program. STUDY DESIGN: A cross-sectional study. METHODS: The MASHAD study started in 2010 and will continue until 2020. Two data mining tools, namely decision trees, and random forests, are used for predicting T2DM when some other characteristics are observed on 9528 subjects recruited from MASHAD database...
April 24, 2018: Journal of Research in Health Sciences
https://www.readbyqxmd.com/read/29784413/a-ricin-forensic-profiling-approach-based-on-a-complex-set-of-biomarkers
#14
Sten-Åke Fredriksson, David S Wunschel, Susanne Wiklund Lindström, Calle Nilsson, Karen Wahl, Crister Åstot
A forensic method for the retrospective determination of preparation methods used for illicit ricin toxin production was developed. The method was based on a complex set of biomarkers, including carbohydrates, fatty acids, seed storage proteins, in combination with data on ricin and Ricinus communis agglutinin. The analyses were performed on samples prepared from four castor bean plant (R. communis) cultivars by four different sample preparation methods (PM1-PM4) ranging from simple disintegration of the castor beans to multi-step preparation methods including different protein precipitation methods...
August 15, 2018: Talanta
https://www.readbyqxmd.com/read/29784007/reporting-to-parents-on-children-s-exposures-to-asthma-triggers-in-low-income-and-public-housing-an-interview-based-case-study-of-ethics-environmental-literacy-individual-action-and-public-health-benefits
#15
Laura J Perovich, Jennifer Liss Ohayon, Elicia Mayuri Cousins, Rachel Morello-Frosch, Phil Brown, Gary Adamkiewicz, Julia Green Brody
BACKGROUND: Emerging evidence about the effects of endocrine disruptors on asthma symptoms suggests new opportunities to reduce asthma by changing personal environments. Right-to-know ethics supports returning personal results for these chemicals to participants, so they can make decisions to reduce exposures. Yet researchers and institutional review boards have been reluctant to approve results reports in low-income communities, which are disproportionately affected by asthma. Concerns include limited literacy, lack of resources to reduce exposures, co-occurring stressors, and lack of models for effective reporting...
May 21, 2018: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/29783965/unmet-basic-needs-negatively-affect-health-related-quality-of-life-in-people-aging-with-hiv-results-from-the-positive-spaces-healthy-places-study
#16
Phan Sok, Sandra Gardner, Tsegaye Bekele, Jason Globerman, Mary V Seeman, Saara Greene, Michael Sobota, Jay J Koornstra, LaVerne Monette, Keith Hambly, Stephen W Hwang, James Watson, Glen Walker, Sean B Rourke
BACKGROUND: Basic needs (e.g., food security and stable housing) are important determinants of health and well-being, yet their impact on health-related quality of life (HRQoL) in the context of HIV and aging has not been systematically investigated. METHODS: Multiple linear regression models examined the relationship between unmet basic needs, and physical and mental HRQoL by age strata (20-34, 35-49 and 50+) in a cross-sectional sample of 496 people living with HIV in Ontario, Canada...
May 21, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29783665/identification-of-novel-somatic-tp53-mutations-in-patients-with-high-grade-serous-ovarian-cancer-hgsoc-using-next-generation-sequencing-ngs
#17
Marica Garziera, Erika Cecchin, Vincenzo Canzonieri, Roberto Sorio, Giorgio Giorda, Simona Scalone, Elena De Mattia, Rossana Roncato, Sara Gagno, Elena Poletto, Loredana Romanato, Franca Sartor, Jerry Polesel, Giuseppe Toffoli
Somatic mutations in TP53 are a hallmark of high-grade serous ovarian cancer (HGSOC), although their prognostic and predictive value as markers is not well defined. Next-generation sequencing (NGS) can identify novel mutations with high sensitivity, that may be repurposed as potential druggable anti-cancer targets and aid in therapeutic decisions. Here, a commercial NGS cancer panel comprising 26 genes, including TP53 , was used to identify new genetic markers of platinum resistance and patient prognosis in a retrospective set of patients diagnosed with epithelial ovarian cancer...
May 18, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29783258/-theoretical-grounds-of-a-structural-and-functional-model-for-quality-assurance-of-radiation-diagnostics-under-conditions-of-development-of-the-modern-health-care-system-in-ukraine
#18
Oleg A Korop, Sergiy V Lenskykh
OBJECTIVE: Introduction: Modern changes in the health care system of Ukraine are focused on financial support in providing medical and diagnostic care to the population and are based on deep and consistent structural and functional transformations. They are aimed at providing adequate quality care, which is the main target function and a principal criterion for operation of health care system. The urgency of this problem is increasing in the context of reforming the health care system and global changes in the governmental financial guarantees for the provision of medical services to the population...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29783253/planning-of-effective-evaluation-of-the-activities-of-hospital-district-at-the-example-of-poltava-region
#19
Vyacheslav M Zhdan, Valentyn M Dvornyk, Viktor P Lysak, Igor M Skrypnyk, Valeriy I Pokhylko, Iryna A Holovanova, Inna V Bielikova, Maxim V Khorosh, Ludmila M Shylkina, Mariya M Tovstiak
OBJECTIVE: Introduction: Increasing of the availability and quality of health care in rural areas is one of the priority directions of public health and regional development policy. The need for reforming of the network of secondary health care facilities is due to the fact, that they are unable to meet the needs of the population in this specialized type of medical care in the conditions of the existing structure and funding system. The aim: to analyze the existing legislation regulating the establishment and operation of hospital districts; to determine the methodology for monitoring and evaluating of the activity of the hospital district on the example of the Poltava region...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29783209/-substantiation-of-the-model-of-clinical-and-economic-efficiency-evaluation-of-prevention-treatment-and-dispenserization-of-the-patients-with-comorbidity-the-example-of-patients-with-arterial-hypertension-and-duodenitis
#20
Anastasiia A Akhmedova, Oleksandr M Ocheredko
OBJECTIVE: Introduction: Evidence based medicine requires reliant estimators of medical programs efficiency both in clinical and economical dimensions. It necessitates the substantiation of evaluation of assessment tools on the ground of clinical and economic theory. Developed model has advantage of direct link with classical economic analyses such as costutility, cost-efficiency, and cost-benefit. The aim was to substantiate the model of clinical and economic efficiency evaluation of medical program with allowance for comorbidity...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
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