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https://www.readbyqxmd.com/read/29326774/the-burden-of-truncus-arteriosus-in-an-urban-city-in-africa-how-are-we-fairing
#1
Barakat Adeola Animasahun, Aminat Titilayo Ogunlana, Henry Olusegun Gbelee
Background: The true incidence of truncus arteriosus in underdeveloped countries is difficult to determine. This is due largely to underreporting as a result of nonavailability of technologically advanced facilities to make definitive diagnosis prenatally. There is a lack of data on the profile and outcome of patients with persistent truncus arteriosus (PTA) in Nigeria. This study aims to document the demographic characteristics, mode of presentation, indications for echocardiography, associated anomalies, average age at diagnosis, and outcome of patients with truncus arteriosus in our center...
October 2017: Heart Views: the Official Journal of the Gulf Heart Association
https://www.readbyqxmd.com/read/29318580/clinico-etiologic-profile-of-hand-dermatitis-and-patch-response-of-patients-at-a-tertiary-hospital-in-lagos-nigeria-results-of-a-prospective-observational-study
#2
Erere Otrofanowei, Olusola O Ayanlowo, Ayesha Akinkugbe, Felix A Oresanya
BACKGROUND: Hand dermatitis is an acute or chronic inflammation of the skin of the hands from a multifactorial cause which may be endogenous, exogenous, or a combination of both. With a wide range in severity and recurrent periods of flares, it has significant impact on the quality of life of its sufferers. A history of atopy predisposes patients to hand dermatitis, but contact dermatitis, either allergic or irritant, is the more commonly implicated factor in the etiology of hand dermatitis...
January 10, 2018: International Journal of Dermatology
https://www.readbyqxmd.com/read/29261503/impact-of-family-planning-and-business-trainings-on-private-sector-health-care-providers-in-nigeria
#3
Jorge Ugaz, Anthony Leegwater, Minki Chatterji, Doug Johnson, Sikiru Baruwa, Modupe Toriola, Cynthia Kinnan
CONTEXT: Private health care providers are an important source of modern contraceptives in Sub-Saharan Africa, yet they face many challenges that might be addressed through targeted training. METHODS: This study measures the impact of a package of trainings and supportive supervision activities targeted to private health care providers in Lagos State, Nigeria, on outcomes including range of contraceptive methods offered, providers' knowledge and quality of counseling, recordkeeping practices, access to credit and revenue...
June 1, 2017: International Perspectives on Sexual and Reproductive Health
https://www.readbyqxmd.com/read/29161827/mathematical-analysis-of-a-weather-driven-model-for-the-population-ecology-of-mosquitoes
#4
Kamaldeen Okuneye, Ahmed Abdelrazec, Abba B Gumel
A new deterministic model for the population biology of immature and mature mosquitoes is designed and used to assess the impact of temperature and rainfall on the abundance of mosquitoes in a community. The trivial equilibrium of the model is globally-asymptotically stable when the associated vectorial reproduction number (R0) is less than unity. In the absence of density-dependence mortality in the larval stage, the autonomous version of the model has a unique and globally-asymptotically stable non-trivial equilibrium whenever 1 andlt;R0 andlt;RC0 (this equilibrium bifurcates into a limit cycle, via a Hopf bifurcation at R0=RC0)...
February 1, 2018: Mathematical Biosciences and Engineering: MBE
https://www.readbyqxmd.com/read/28717726/breast-cancer-reporting-in-lagos-nigeria-implications-for-training-and-education-in-africa
#5
Adetola O Daramola, Adekunbiola A Banjo, Aneliese Bennett, Fatimah Abdulkareem, Abeer M Shaaban
PURPOSE: To assess the completeness and accuracy of breast cancer pathologic reporting in Nigeria. MATERIALS AND METHODS: The histologic parameters provided in breast cancer pathology reports at a large teaching hospital in Nigeria were assessed. The corresponding slides were reviewed after the United Kingdom Royal College of Pathologists guidelines, and results were compared. RESULTS: Out of 115 breast cancer cases, histologic type of breast carcinoma was concordant with the review type in 53...
December 2016: Journal of Global Oncology
https://www.readbyqxmd.com/read/28589272/heavy-metals-distribution-and-risk-assessment-in-soil-from-an-informal-e-waste-recycling-site-in-lagos-state-nigeria
#6
Khadijah A Isimekhai, Hemda Garelick, John Watt, Diane Purchase
Informal E-waste recycling can pose a risk to human health and the environment which this study endeavours to evaluate. The distribution of a number of heavy metals in soil from an informal recycling site in the largest market for used and new electronics and electrical equipment in West Africa was investigated. The potential bioavailability of heavy metals, extent of contamination, potential risk due to the recycling activities and impact of external factors such as rainfall were also assessed. The concentrations of all the heavy metals tested were higher in the area where burning of the waste occurred than at the control site, suggesting an impact of the recycling activities on the soil...
July 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28364926/transforming-vaccines-supply-chains-in-nigeria
#7
David Sarley, Mustafa Mahmud, Jide Idris, Modele Osunkiyesi, Onome Dibosa-Osadolor, Peter Okebukola, Owens Wiwa
Nigeria is the most populous country in Africa and in 2012 was suffering some of the lowest vaccination rates in the World. A combination of factors had resulted in a dysfunctional immunization cold chain and supply chain. Recognizing that the number of unimmunized children contributed to high levels of under-5-mortality, and that health MDGs would not be attained, Minister of State for Health Mohammed Pate launched a vaccines transformation project in 2013. In partnership with BMGF, GAVI, UNICEF, WHO, other donors and implementing partners the transformation journey has so far taken three years and achieved impressive results...
April 19, 2017: Vaccine
https://www.readbyqxmd.com/read/28091428/refractive-aim-and-visual-outcome-after-phacoemulsification-a-2-year-review-from-a-tertiary-private-eye-hospital-in-sub-saharan-africa
#8
O Oderinlo, A O Hassan, F O Oluyadi, A O Ogunro, O N Okonkwo, M O Ulaikere, O Ashano
AIM: To review the short-term visual outcome of phacoemulsification in adults with uncomplicated cataracts in Eye Foundation Hospital, Lagos, Nigeria. MATERIALS AND METHODS: A retrospective review of records of patients that had phacoemulsification between January 2012 and December 2013 in Eye Foundation Hospital, Lagos, Nigeria, was done. Preoperative visual acuity, refractive aim, intraoperative complications, postoperative unaided, and best-corrected visual acuity at 1 and 3 months were analyzed...
February 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/27990294/prevalence-and-associated-factors-for-suicidal-ideation-in-the-lagos-state-mental-health-survey-nigeria
#9
Abiodun O Adewuya, Bolanle A Ola, Olurotimi A Coker, Olayinka Atilola, Mathew P Zachariah, Olufemi Olugbile, Adedolapo Fasawe, Olajide Idris
BACKGROUND: To combat the increasing rate of suicide, basic data on suicidal behaviours reflecting the uniqueness of the locality are needed in sub-Saharan Africa. AIMS: To assess the prevalence of suicidal ideation and associated factors. METHOD: Adults (n=11 246) from the five administrative divisions of Lagos State completed questionnaires detailing suicidal ideation, socio-demographic details, common mental disorders (depression, anxiety and somatic symptoms), alcohol and psychoactive substance use disorders and disability...
November 2016: BJPsych Open
https://www.readbyqxmd.com/read/27843830/international-classification-of-primary-care-2-coding-of-primary-care-data-at-the-general-out-patients-clinic-of-general-hospital-lagos-nigeria
#10
Olawunmi Abimbola Olagundoye, Kees van Boven, Chris van Weel
BACKGROUND: Primary care serves as an integral part of the health systems of nations especially the African continent. It is the portal of entry for nearly all patients into the health care system. Paucity of accurate data for health statistics remains a challenge in the most parts of Africa because of inadequate technical manpower and infrastructure. Inadequate quality of data systems contributes to inaccurate data. A simple-to-use classification system such as the International Classification of Primary Care (ICPC) may be a solution to this problem at the primary care level...
April 2016: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/27836020/high-levels-of-pre-treatment-hiv-drug-resistance-and-treatment-failure-in-nigerian-children
#11
Ragna S Boerma, T Sonia Boender, Kim C E Sigaloff, Tobias F Rinke de Wit, Michael Boele van Hensbroek, Nicaise Ndembi, Titilope Adeyemo, Edamisan O Temiye, Akin Osibogun, Pascale Ondoa, Job C Calis, Alani Sulaimon Akanmu
INTRODUCTION: Pre-treatment HIV drug resistance (PDR) is an increasing problem in sub-Saharan Africa. Children are an especially vulnerable population to develop PDR given that paediatric second-line treatment options are limited. Although monitoring of PDR is important, data on the paediatric prevalence in sub-Saharan Africa and its consequences for treatment outcomes are scarce. We designed a prospective paediatric cohort study to document the prevalence of PDR and its effect on subsequent treatment failure in Nigeria, the country with the second highest number of HIV-infected children in the world...
2016: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/27806714/the-emerging-threat-of-pre-extensively-drug-resistant-tuberculosis-in-west-africa-preparing-for-large-scale-tuberculosis-research-and-drug-resistance-surveillance
#12
Florian Gehre, Jacob Otu, Lindsay Kendall, Audrey Forson, Awewura Kwara, Samuel Kudzawu, Aderemi O Kehinde, Oludele Adebiyi, Kayode Salako, Ignatius Baldeh, Aisha Jallow, Mamadou Jallow, Anoumou Dagnra, Kodjo Dissé, Essosimna A Kadanga, Emmanuel Oni Idigbe, Catherine Onubogu, Nneka Onyejepu, Aissatou Gaye-Diallo, Awa Ba-Diallo, Paulo Rabna, Morto Mane, Moumine Sanogo, Bassirou Diarra, Zingue Dezemon, Adama Sanou, Madikay Senghore, Brenda A Kwambana-Adams, Edward Demba, Tutty Faal-Jawara, Samrat Kumar, Leopold D Tientcheu, Adama Jallow, Samba Ceesay, Ifedayo Adetifa, Assan Jaye, Mark J Pallen, Umberto D'Alessandro, Beate Kampmann, Richard A Adegbola, Souleymane Mboup, Tumani Corrah, Bouke C de Jong, Martin Antonio
BACKGROUND: Drug-resistant tuberculosis (TB) is a global public health problem. Adequate management requires baseline drug-resistance prevalence data. In West Africa, due to a poor laboratory infrastructure and inadequate capacity, such data are scarce. Therefore, the true extent of drug-resistant TB was hitherto undetermined. In 2008, a new research network, the West African Network of Excellence for Tuberculosis, AIDS and Malaria (WANETAM), was founded, comprising nine study sites from eight West African countries (Burkina Faso, The Gambia, Ghana, Guinea-Bissau, Mali, Nigeria, Senegal and Togo)...
November 3, 2016: BMC Medicine
https://www.readbyqxmd.com/read/27789246/detection-of-toxigenic-clostridium-perfringens-and-clostridium-botulinum-from-food-sold-in-lagos-nigeria
#13
Emelda E Chukwu, Francisca O Nwaokorie, Akitoye O Coker, Mario J Avila-Campos, Rosa L Solis, Luis A Llanco, Folasade T Ogunsola
Food-borne diseases contribute to the huge burden of sickness and death globally and in the last decade, have become more frequently reported in Africa. In line with this, food safety is becoming a significant and growing public health problem in Nigeria. Diarrhoea is a common problem in Nigeria and has been reported but there has been little data on the possibility of clostridia as aetiological agents. Clostridium species are ubiquitous in the environment and in the gastrointestinal tract of man and animals and can serve as a marker for faecal contamination...
December 2016: Anaerobe
https://www.readbyqxmd.com/read/27771618/juvenile-systemic-lupus-erythematosus-in-nigeria
#14
O O Adelowo, B H Olaosebikan, B A Animashaun, R O Akintayo
Juvenile systemic lupus erythematosus (JSLE) is a complex multisystemic autoimmune disorder of unknown cause. It accounts for about one in five cases of SLE. The tendency for SLE to run a fulminant course when it starts in childhood has made JSLE a potentially more severe disease than adult SLE. Reports of JSLE from sub-Saharan Africa are scanty in spite of the increasing reports of adult SLE. We conducted a 4-year retrospective study of JSLE cases seen at the Lagos State University Teaching Hospital between January 2010 and December 2014...
March 2017: Lupus
https://www.readbyqxmd.com/read/27747169/the-burden-of-fallot-s-tetralogy-among-nigerian-children
#15
Barakat Adeola Animasahun, Akpoembele D Madise-Wobo, Bode A Falase, Samuel I Omokhodion
BACKGROUND: There are only very few reports on Fallot's tetralogy in Africa especially from sub-Saharan Africa. At best tetralogy of Fallot (TOF) is only mentioned as part of reports of surveys of other congenital heart diseases or as case reports in the region. There has been no report on cohorts of children with TOF in West Africa. This article describes the pattern and presentation of children diagnosed with TOF patients in a tertiary hospital in sub-Saharan Africa over a 9-year period...
October 2016: Cardiovascular Diagnosis and Therapy
https://www.readbyqxmd.com/read/27664176/private-sector-participation-in-domestic-waste-management-in-informal-settlements-in-lagos-nigeria
#16
Akunnaya P Opoko, Adedapo A Oluwatayo
Lagos is one of the fastest growing cities in Africa, which is grappling with the challenges of poorly managed urbanisation. With an estimated population of about 17.5 million, solid waste management is one of the most pressing environmental challenges currently faced in the city. It is estimated that more than 9071847.4kg of urban waste is generated every day in the city. The city lacks the capacity to deal with such magnitude of waste. Consequently, the city has involved the private sector (private sector participation) in its waste management drive...
December 2016: Waste Management & Research
https://www.readbyqxmd.com/read/27575939/clinical-profile-and-containment-of-the-ebola-virus-disease-outbreak-in-two-large-west-african-cities-nigeria-july-september-2014
#17
Chima Ohuabunwo, Celestine Ameh, Oyin Oduyebo, Anthony Ahumibe, Bamidele Mutiu, Adebola Olayinka, Wasiu Gbadamosi, Erika Garcia, Carolina Nanclares, Wale Famiyesin, Abdulaziz Mohammed, Patrick Nguku, Richard I Koko, Joshua Obasanya, Durojaye Adebayo, Yemi Gbadegesin, Oni Idigbe, Olukayode Oguntimehin, Sara Nyanti, Charles Nzuki, Ismail Abdus-Salam, Joseph Adeyemi, Nnanna Onyekwere, Emmanuel Musa, David Brett-Major, Faisal Shuaib, Abdulsalami Nasidi
INTRODUCTION: The Ebola virus disease (EVD) outbreak in Nigeria began when an infected diplomat from Liberia arrived in Lagos, the most populous city in Africa, with subsequent transmission to another large city. METHODS: First-, second-, and third-generation contacts were traced, monitored, and classified. Symptomatic contacts were managed at Ebola treatment centers as suspected, probable, and confirmed EVD cases using standard operating procedures adapted from the World Health Organization EVD guidelines...
December 2016: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/27574769/conception-of-pharmacological-knowledge-and-needs-amongst-nigerian-medical-students-at-lagos-state-university-college-of-medicine-implication-for-future-biomedical-science-in-africa
#18
Luther Agbonyegbeni Agaga, Theresa Adebola John
In Nigeria, medical students are trained in more didactic environments than their counterparts in researchintensive academic medical centers. Their conception of pharmacology was thus sought. Students who are taking/have takenthe medical pharmacology course completed an 18-question survey within 10min by marking one/more choices fromalternatives. Instructions were: "Dear Participant, Please treat as confidential, give your true view, avoid influences, avoidcrosstalk, return survey promptly." Out of 301 students, 188 (62...
August 30, 2016: Nigerian Journal of Physiological Sciences: Official Publication of the Physiological Society of Nigeria
https://www.readbyqxmd.com/read/27547200/microbial-communities-in-sediments-of-lagos-lagoon-nigeria-elucidation-of-community-structure-and-potential-impacts-of-contamination-by-municipal-and-industrial-wastes
#19
Chioma C Obi, Sunday A Adebusoye, Esther O Ugoji, Mathew O Ilori, Olukayode O Amund, William J Hickey
Estuarine sediments are significant repositories of anthropogenic contaminants, and thus knowledge of the impacts of pollution upon microbial communities in these environments is important to understand potential effects on estuaries as a whole. The Lagos lagoon (Nigeria) is one of Africa's largest estuarine ecosystems, and is impacted by hydrocarbon pollutants and other industrial and municipal wastes. The goal of this study was to elucidate microbial community structure in Lagos lagoon sediments to identify groups that may be adversely affected by pollution, and those that may serve as degraders of environmental contaminants, especially polycyclic aromatic hydrocarbons (PAHs)...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27512845/significant-contribution-of-subtype-g-to-hiv-1-genetic-complexity-in-nigeria-identified-by-a-newly-developed-subtyping-assay-specific-for-subtype-g-and-crf02_ag
#20
Richard A Heipertz, Ojor Ayemoba, Eric Sanders-Buell, Kultida Poltavee, Phuc Pham, Gustavo H Kijak, Esther Lei, Meera Bose, Shana Howell, Anne Marie OʼSullivan, Adam Bates, Taylor Cervenka, Janelle Kuroiwa, Akindiran Akintunde, Onyekachukwu Ibezim, Abraham Alabi, Obumneke Okoye, Mark Manak, Jennifer Malia, Sheila Peel, Mohammed Maisaka, Darrell Singer, Robert J O'Connell, Merlin L Robb, Jerome H Kim, Nelson L Michael, Ogbonnaya Njoku, Sodsai Tovanabutra
While abundant sequence information is available from human immunodeficiency virus type 1 (HIV-1) subtypes A, B, C and CRF01_AE for HIV-1 vaccine design, sequences from West Africa are less represented. We sought to augment our understanding of HIV-1 variants circulating in 6 Nigerian cities as a step to subsequent HIV-1 vaccine development.The G/CRF02_AG multi-region hybridization assay (MHA) was developed to differentiate subtype G, CRF02_AG and their recombinants from other subtypes based on 7 HIV-1 segments...
August 2016: Medicine (Baltimore)
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