keyword
MENU ▼
Read by QxMD icon Read
search

ace

keyword
https://www.readbyqxmd.com/read/29346111/single-scan-high-resolution-2-d-j-resolved-spectroscopy-in-inhomogeneous-magnetic-fields
#1
Kaiyu Wang, Yuqing Huang, Pieter E S Smith, Zhiyong Zhang, Shuhui Cai, Zhong Chen
OBJECTIVE: A method is proposed to obtain high-resolution 2-D -resolved nuclear magnetic resonance (NMR) spectra in inhomogeneous magnetic fields. METHODS: The proposed experiment enables the acquisition of an entire 2-D spectrum in a single scan by utilizing intermolecular double-quantum coherences and the spatial encoding of NMR observables. RESULTS: Chemical shifts, coupling constants, and multiplet patterns are recovered even when field inhomogeneities are severe enough to completely obscure conventional NMR spectra...
February 2018: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/29345962/role-of-selected-polymorphisms-in-determining-muscle-fiber-composition-in-japanese-men-and-women
#2
Hiroshi Kumagai, Takuro Tobina, Noriko Ichinoseki-Sekine, Ryo Kakigi, Takamasa Tsuzuki, Hirofumi Zempo, Keisuke Shiose, Eiichi Yoshimura, Hideaki Kumahara, Makoto Ayabe, Yasuki Higaki, Ryo Yamada, Hiroyuki Kobayashi, Akira Kiyonaga, Hisashi Naito, Hiroaki Tanaka, Noriyuki Fuku
Genetic polymorphisms and sex differences are suggested to affect muscle fiber composition; however, no study has investigated the effects of genetic polymorphisms on muscle fiber composition with respect to sex differences. Therefore, the present study examined the effects of genetic polymorphisms on muscle fiber composition with respect to sex differences in Japanese population. The present study included 211 healthy Japanese individuals (102 men and 109 women). Muscle biopsies were obtained from the vastus lateralis to determine the proportion of myosin heavy chain isoforms (MHC-I, MHC-IIa, and MHC-IIx)...
January 18, 2018: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29345929/antihypertensive-effects-molecular-docking-study-and-isothermal-titration-calorimetry-assay-of-the-angiotensin-i-converting-enzyme-inhibitory-peptides-from-chlorella-vulgaris
#3
Jingli Xie, Xujun Chen, Junjie Wu, Yanyan Zhang, Yan Zhou, Lujia Zhang, Yajie Tang, Dong-Zhi Wei
The aim of this work is to explore angiotensin I-converting enzyme (ACE) inhibitory peptides from Chlorella vulgaris (C. vulgaris) and discover the inhibitory mechanism of the peptides. After C. vulgaris proteins were gastrointestinal digested in silico, several ACE inhibitory peptides with C-terminal tryptophan were screened. Among them, two novel non-competitive ACE inhibitors, Thr-Thr-Trp (TTW) and Val-His-Trp (VHW), exhibited the highest inhibitory activity indicated by IC50 values, 0.61 ± 0.12 and 0.91 ± 0...
January 18, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29345540/cost-effectiveness-analysis-of-asymptomatic-peripheral-artery-disease-screening-with-the-abi-test
#4
Nathan K Itoga, Hataka R Minami, Meenadachi Chelvakumar, Keon Pearson, Matthew M Mell, Eran Bendavid, Douglas K Owens
Screening for asymptomatic peripheral artery disease (aPAD) with the ankle-brachial index (ABI) test is hypothesized to reduce disease progression and cardiovascular (CV) events by identifying individuals who may benefit from early initiation of medical therapy. Using a Markov model, we evaluated the cost effectiveness of initiating medical therapy (e.g. statin and ACE-inhibitor) after a positive ankle-brachial index (ABI) screen in 65-year-old patients. We modeled progression to symptomatic PAD (sPAD) and CV events with and without ABI screening, evaluating differences in costs and quality-adjusted life years (QALYs)...
January 1, 2018: Vascular Medicine
https://www.readbyqxmd.com/read/29345462/fluorescent-zn-pdc-tb3-coordination-polymer-nanostructure-a-candidate-for-highly-selective-detections-of-cefixime-antibiotic-and-acetone-in-aqueous-system
#5
Hong Pan, Sufan Wang, Xiaoyao Dao, Yonghong Ni
Tb3+-doped zinc-based coordination polymer nanospindle bundles (Zn-PDC/Tb3+, or [Zn(2,5-PDC)(H2O)2]·H2O/Tb3+) were synthesized by a simple solution precipitation route at room temperature, employing Zn(NO3)2, Tb(NO3)3, and 2,5-Na2PDC as the initial reactants, and a mixture of water and ethanol with the volume ratio of 10:10 as the solvent. The as-obtained nanostructures presented strong fluorescent emission under the excitation of 298 nm light, which was attributed to the characteristic emission of the Tb3+ ion...
January 18, 2018: Inorganic Chemistry
https://www.readbyqxmd.com/read/29345425/eligibility-of-sacubitril-valsartan-in-a-real-world-heart-failure-population-a-community-based-single-centre-study
#6
Helena Norberg, Ellinor Bergdahl, Krister Lindmark
AIMS: This study aims to investigate the eligibility of the Prospective Comparison of Angiotensin Receptor-Neprilysin Inhibitor (ARNI) with ACE inhibitor to Determine Impact on Global Mortality and Morbidity in Heart Failure (PARADIGM-HF) study to a real-world heart failure population. METHODS AND RESULTS: Medical records of all heart failure patients living within the catchment area of Umeå University Hospital were reviewed. This district consists of around 150 000 people...
January 18, 2018: ESC Heart Failure
https://www.readbyqxmd.com/read/29345131/photolithography-based-nanopatterning-using-re-entrant-photoresist-profile
#7
Tong Kim, Yei Hwan Jung, Huilong Zhang, Kwangeun Kim, Juhwan Lee, Zhenqiang Ma
Photolithography based on optical mask is widely used in academic research laboratories due to its low-cost, simple mechanism, and ability to pattern in micron sized features on a wafer scale area. Since the resolution is bound by diffraction limits of the light source, nano-scale patterning using photolithography requires short wavelength light source combined with sophisticated optical elements, adding complexity and cost. In this paper, a novel method of sub-wavelength patterning process using conventional i-line mercury lamp is introduced, without the use of such advanced optical tools...
January 18, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29344922/impact-of-renin-angiotensin-aldosterone-system-polymorphisms-on-myocardial-perfusion-correlations-with-myocardial-single-photon-emission-computed-tomography-derived-parameters
#8
George Angelidis, Maria Samara, Maria Papathanassiou, Maria Satra, Varvara Valotassiou, Ioannis Tsougos, Dimitrios Psimadas, Chara Tzavara, Sotiria Alexiou, John Koutsikos, Nikolaos Demakopoulos, Gregory Giamouzis, Filippos Triposkiadis, John Skoularigis, Panagoula Kollia, Panagiotis Georgoulias
BACKGROUND: Renin-angiotensin-aldosterone system (RAAS) has an important role in atherosclerosis. We investigated the effects of six RAAS gene polymorphisms on myocardial perfusion. METHODS AND RESULTS: We examined 810 patients with known or suspected coronary artery disease (CAD) using stress-rest myocardial single-photon emission computed tomography. Summed stress score (SSS), summed rest score (SRS), summed difference score (SDS), transient ischemic dilation (TID), and lung/heart ratio (LHR) were recorded...
January 17, 2018: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29344035/hypercalcaemic-pancreatitis-adrenal-insufficiency-autoimmune-thyroiditis-and-diabetes-mellitus-in-a-girl-with-probable-sarcoidosis
#9
Devi Dayal, Olivia Pepper, Renuka Ramakrishnan, Eileen Baildam, Poonam Dharmaraj, Gavin Cleary, Liza McCann, Clare Pain, Senthil Senniappan
Introduction: Sarcoidosis is a multisystemic granulomatous disease with diverse and often non-specific symptoms during childhood. The clinical manifestations sometimes include endocrinopathies related to sarcoid infiltration of various endocrine organs, but more commonly due to the associated autoimmune endocrine disorders. There are only a few reports of multiple autoimmune and non-autoimmune endocrine problems occurring simultaneously in patients with sarcoidosis. We report a girl with probable sarcoidosis who also had Hashimoto's thyroiditis, Type 1 diabetes (T1D) and secondary adrenal insufficiency...
October 2017: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29342360/sustained-delivery-of-doxorubicin-via-acetalated-dextran-scaffold-prevents-glioblastoma-recurrence-after-surgical-resection
#10
Elizabeth G Graham-Gurysh, Kathryn M Moore, Andrew B Satterlee, Kevin T Sheets, Feng-Chang Lin, Eric M Bachelder, C Ryan Miller, Shawn Hingtgen, Kristy M Ainslie
The primary cause of mortality for glioblastoma (GBM) is local tumor recurrence following standard-of-care therapies, including surgical resection. With most tumors recurring near the site of surgical resection, local delivery of chemotherapy at the time of surgery is a promising strategy. Herein drug loaded polymer scaffolds with two distinct degradation profiles were fabricated to investigate the effect of local drug delivery rate on GBM recurrence following surgical resection. The novel biopolymer, acetalated dextran (Ace-DEX), was compared to commercially available polyester, poly(L-lactide) (PLA)...
January 17, 2018: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/29341589/metal-organic-frameworks-mofs-derived-hierarchical-co3o4-structures-as-efficient-sensing-materials-for-acetone-detection
#11
Rui Zhang, Tingting Zhou, Lili Wang, Tong Zhang
High sensitive and stable gas sensors have attracted much attention because they are the key to innovations in the fields of environment, health, energy savings and security, etc. Sensing materials, which influence the practical sensing performance, are the crucial parts for gas sensors. Metal-organic frameworks (MOFs) are considered as alluring sensing materials for gas sensors due to the possession of high specific surface area, unique morphology, abundant metal sites and functional linkers. Herein, four kinds of porous hierarchical Co3O4 structures have been selectively controlled by optimizing the thermal decomposition (temperature, rate and atmosphere) using ZIF-67 as precursor that was obtained from coprecipitation method with the co-assistant of cobalt salt and 2-methylimidazole in the solution of methanol...
January 17, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29341471/the-impact-of-a-dose-of-the-angiotensin-receptor-blocker-valsartan-on-post-myocardial-infarction-ventricular-remodelling
#12
Kyungil Park, Young-Dae Kim, Ki-Sik Kim, Su-Hoon Lee, Tae-Ho Park, Sang-Gon Lee, Byung-Soo Kim, Seung-Ho Hur, Tae-Hyun Yang, Joo-Hyun Oh, Taek-Jong Hong, Jong-Sun Park, Jin-Yong Hwang, Byungcheon Jeong, Woo-Hyung Bae
AIMS: Although clinical guidelines advocate the use of the highest tolerated dose of angiotensin-converting enzyme inhibitors or angiotensin receptor blockers after acute myocardial infarction (MI), the optimal dosing or the risk-benefit profile of different doses have not been fully identified. METHODS AND RESULTS: In this multicentre trial, 495 Korean patients with acute ST segment elevation MI and subnormal left ventricular (LV) ejection fraction (<50%) were randomly allocated (2:1) to receive maximal tolerated dose of valsartan (titrated up to 320 mg/day, n = 333) or low-dose valsartan (80 mg/day, n = 162) treatment...
January 17, 2018: ESC Heart Failure
https://www.readbyqxmd.com/read/29340654/antioxidant-angiotensin-converting-enzyme-inhibitory-activity-and-other-functional-properties-of-egg-white-proteins-and-their-derived-peptides-a-review
#13
E D N S Abeyrathne, X Huang, D U Ahn
Egg white contains many functionally important proteins: ovalbumin (54%), ovotransferrin (12%), ovomucoid (11%), ovoglobulin (G2 and G3, 8%), ovomucin (3.5%), and lysozyme (3.5%) are major proteins, while ovoinhibitors, ovomacroglobulin, ovoglycoprotein, ovoflavoprotein, thiamine-binding proteins, and avidin are minor proteins present in egg white. These proteins, as well as the peptides derived from the proteins, have been recognized for their functional importance as antioxidant, antimicrobial, metal-chelating, anti-viral, anti-tumour, and angiotensin-converting enzyme (ACE)-inhibitory activities...
January 11, 2018: Poultry Science
https://www.readbyqxmd.com/read/29340005/comparison-of-aerobic-performance-testing-protocols-in-elite-male-wheelchair-basketball-players
#14
Bartosz Molik, Andrzej Kosmol, Natalia Morgulec-Adamowicz, Judit Lencse-Mucha, Anna Mróz, Karol Gryko, Jolanta Marszałek
In wheelchair sports, aerobic performance is commonly assessed with the use of an arm crank ergometer (ACE), a wheelchair ergometer (WCE) or a wheelchair treadmill (WCT). There are different protocols to identify peak oxygen uptake in wheelchair sports; however, only a few protocols have been applied to evaluate these conditions in wheelchair basketball players. The purpose of this study was to compare physiological responses during maximal exercise testing with the use of ACE and WCT in wheelchair basketball players...
December 2017: Journal of Human Kinetics
https://www.readbyqxmd.com/read/29339688/choice-of-treatment-based-on-turkish-hypertension-consensus-report-do-we-follow-the-recommendations
#15
Gülden Yürüyen, İlkim Deniz Toprak, Zeki Toprak, Murat Akarsu, Pınar Demir, Yücel Arman, Eylem Özgün Çil, Mustafa Özcan, Sedat Irmak, Özgür Altun, Şengül Aydın Yoldemir, Hasan Eruzun, Tufan Tükek
OBJECTIVE: The aim of this study was to determine how often the recommendations of the Turkish Hypertension Consensus Report are followed, and to draw attention to the report. METHODS: The demographic information of 1000 patients diagnosed with hypertension and the details of the antihypertensive medications prescribed at the outpatient service of a tertiary care hospital were recorded, and the data were compared with the recommendations of the report. RESULTS: The mean age of the patients was 62±11 years...
January 2018: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/29338788/high-throughput-immunophenotypic-characterization-of-bone-marrow-and-cord-blood-derived-mesenchymal-stromal-cells-reveals-common-and-differentially-expressed-markers-identification-of-angiotensin-converting-enzyme-cd143-as-a-marker-differentially-expressed
#16
Eliana Amati, Omar Perbellini, Gianluca Rotta, Martina Bernardi, Katia Chieregato, Sabrina Sella, Francesco Rodeghiero, Marco Ruggeri, Giuseppe Astori
BACKGROUND: Mesenchymal stromal cells (MSC) are a heterogeneous population of multipotent progenitors used in the clinic because of their immunomodulatory properties and their ability to differentiate into multiple mesodermal lineages. Although bone marrow (BM) remains the most common MSC source, cord blood (CB) can be collected noninvasively and without major ethical concerns. Comparative studies comprehensively characterizing the MSC phenotype across several tissue sources are still lacking...
January 16, 2018: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/29338315/the-chronic-ischaemic-cardiovascular-disease-esc-pilot-registry-results-of-the-six-month-follow-up
#17
Michel Komajda, Mathieu Kerneis, Luigi Tavazzi, Serban Balanescu, Francesco Cosentino, Alberto Cremonesi, Roberto Ferrari, Serge Kownator, Hanna Szwed, Iveta Mintale, Zoran Olivari, Harald Rittger, Evgeny V Shlyakhto, Rimvydas Slapikas, Philippe Gabriel Steg, Marco Valgimigli, Eric Van Belle, Konstantinos Tsioufis, Wojciech Majda, Cécile Laroche, Aldo P Maggioni
Aim Chronic ischaemic cardiovascular disease (CICD) remains a leading cause of morbidity and mortality worldwide. The CICD Pilot Registry enrolled 2420 patients across 10 European Society of Cardiology countries prospectively to describe characteristics, management strategies and clinical outcomes in this setting. We report here the six-month outcomes. Methods and results From the overall population, 2203 patients were analysed at six months. Fifty-eight patients (2.6%) died after inclusion; 522 patients (23...
January 1, 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29337383/the-national-pregnancy-in-diabetes-npid-audit-challenges-and-opportunities-for-improving-pregnancy-outcomes
#18
H R Murphy, R Bell, A Dornhorst, R Forde, N Lewis-Barned
Our aim was to review the data from the National Pregnancy in Diabetes (NPID) audit, and to identify the challenges and opportunities for improving pregnancy outcomes in women with diabetes. We reviewed three years of NPID data and relevant diabetes and obstetric literature, and found that there has been little change in pregnancy preparation or outcomes over the past 3 years, with substantial clinic-to clinic variations in care. Women with Type 2 diabetes remain less likely to take 5 mg preconception folic acid (22...
January 16, 2018: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29337321/synthesis-spectroscopic-investigation-and-dft-study-of-n-n-disubstituted-ferrocene-based-thiourea-complexes-as-potent-anticancer-agents
#19
Faiza Asghar, Saira Fatima, Sadaf Rana, Amin Badshah, Ian S Butler, Muhammad Nawaz Tahir
In the present work, the synthesis, characterization (FT-IR, multinuclear (1H and 13C) NMR, AAS, Raman, and elemental analyses), DNA binding (cyclic voltammetry, UV-Vis spectroscopy), and in vitro biological screening of nine new ferrocene-incorporated thioureas (A1-A9) are reported. Furthermore, the single-crystal X-ray structure of compound A8 was also determined. The ferrocene-based N,N'-disubstituted thioureas were derived by allowing the ferrocenyl anilines to react with freshly prepared isothiocyanates under a N2 atmosphere in dry acetone...
January 16, 2018: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29337283/variability-studies-of-allochthonous-stone-pine-pinus-pinea-l-plantations-in-chile-through-nut-protein-profiling
#20
V Loewe, R M Navarro-Cerrillo, R Sánchez Lucas, F J Ruiz Gómez, J Jorrín-Novo
Stone pine (Pinus pinea) is characterized by low differentiation of growth parameters, high phenotypic plasticity and low genetic variability; detecting its diversity in introduced Chilean populations is therefore relevant for conservation and breeding programs. Here, variability among allochthonous Stone pine populations in Chile was explored using electrophoresis-based proteomic analysis of pine nuts. Cones from 30 populations distributed along a climatic gradient in Chile were surveyed and sampled, and proteins were extracted from seed flour using the TCA-acetone precipitation protocol...
January 11, 2018: Journal of Proteomics
keyword
keyword
15205
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"