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https://www.readbyqxmd.com/read/29218481/concepts-for-a-therapeutic-prolongation-of-nephrogenesis-in-preterm-and-low-birth-weight-babies-must-correspond-to-structural-functional-properties-in-the-nephrogenic-zone
#1
REVIEW
Will W Minuth
Numerous investigations are dealing with anlage of the mammalian kidney and primary development of nephrons. However, only few information is available about the last steps in kidney development leading at birth to a downregulation of morphogen activity in the nephrogenic zone and to a loss of stem cell niches aligned beyond the organ capsule. Surprisingly, these natural changes in the developmental program display similarities to processes occurring in the kidneys of preterm and low-birth-weight babies. Although those babies are born at a time with a principally intact nephrogenic zone and active niches, a high proportion of them suffers on impairment of nephrogenesis resulting in oligonephropathy, formation of atypical glomeruli, and immaturity of parenchyma...
December 7, 2017: Molecular and Cellular Pediatrics
https://www.readbyqxmd.com/read/29217168/the-stories-of-women-who-are-transferred-due-to-threat-of-preterm-birth
#2
Lyn Woodhart, Jessica Goldstone, Donna Hartz
BACKGROUND: Women at risk of preterm birth before 32 weeks gestation are routinely transferred to facilitate birth at a hospital that has Neonatal Intensive Care. The clinical outcomes of being 'in-born" improves newborn and neonatal outcomes is well documented. However little is known about the women's experiences when such a complication occurs. METHOD: Using the NSW Agency for Clinical Innovation Patient and Carer stories method, 10 women were purposively invited and consented to tell their stories...
December 4, 2017: Women and Birth: Journal of the Australian College of Midwives
https://www.readbyqxmd.com/read/29216238/mother-infant-interaction-assessment-at-discharge-and-at-6-months-in-a-french-cohort-of-infants-born-very-preterm-the-olimpe-study
#3
Gilles Cambonie, Jean-Baptiste Muller, Virginie Ehlinger, Joël Roy, Antoine Guédeney, Cécile Lebeaux, Monique Kaminski, Corine Alberge, Sophie Denizot, Pierre-Yves Ancel, Catherine Arnaud
OBJECTIVES: The principal aim was to investigate the feasibility of assessing mother-infant interactions at discharge and at 6 months infant corrected age in singletons born before 32 weeks of gestation. The secondary aims were to describe these interactions and their disorders, explore the association between maternal emotional state and the interactions, and assess the relationship between disordered interactions and infant social withdrawal behaviour. METHODS: OLIMPE is an ancillary study of the population-based study EPIPAGE 2, which recruited preterm neonates in France in 2011...
2017: PloS One
https://www.readbyqxmd.com/read/29214043/folic-acid-level-and-preterm-birth-among-sudanese-women
#4
Manal E Sharif, Ahmed Mohamedain, AbdelBagi A Ahmed, Abubakr M Nasr, Ishag Adam
Background: Preterm birth (PTB) is the major health problem world-wide; there are few published studies on PTB and folic acid. Methods: The study was conducted to assess the serum level of folic acid in PTB. A case-control study was conducted at Saad Abualila maternity hospital (Khartoum, Sudan) during the period of March through December 2015. Women who delivered live singleton babies were dived in two groups; the cases were women who had PTB "delivery before completed 37weeks but after 24 weeks of pregnancy" and the controls were women who delivered at term (37-42 weeks)...
2017: Maternal Health, Neonatology and Perinatology
https://www.readbyqxmd.com/read/29208875/predicting-neonatal-hyperbilirubinemia-using-first-day-serum-bilirubin-level-in-late-preterm-and-term-healthy-newborn
#5
K A Khan, J Alam, N Nahar, S K Dey, M A Mannan, M Shahidullah
Hyperbilirubinemia is a common problem during the neonatal period and is the most common reason for readmission after early hospital discharge of the healthy near term and term infants. This early discharge policy along with limited follow-up facilities in developing countries and inadequate communication between physicians and parents necessitates a prognostic test to predict hyperbilirubinemia in these newborns; for early and effective management and prevention of potential complication before it occurred...
October 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29206936/birthweight-of-singletons-born-after-cleavage-stage-or-blastocyst-transfer-in-fresh-and-warming-cycles
#6
Anick De Vos, Samuel Santos-Ribeiro, Lisbet Van Landuyt, Hilde Van de Velde, Herman Tournaye, Greta Verheyen
STUDY QUESTION: Does extended culture to the blastocyst stage affect singleton birthweight after either fresh or vitrified-warmed embryo transfer? SUMMARY ANSWER: Singleton birthweight z-scores did not vary significantly after a fresh blastocyst transfer, whereas the additional effect of vitrification remains inconclusive. WHAT IS KNOWN ALREADY: Observational studies have associated extended culture with an increased risk of preterm birth and low birthweight...
December 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29201825/the-validity-of-the-bayley-iii-and-ddst-ii-in-preterm-infants-with-neurodevelopmental-impairment-a-pilot-study
#7
Seong Uk Jeong, Ghi Chan Kim, Ho Joong Jeong, Dong Kyu Kim, Yoo Rha Hong, Hui Dong Kim, Seok Gyo Park, Young-Joo Sim
Objective: To identify the usefulness of both the Bayley Scales of Infant and Toddler Development, 3rd edition (Bayley-III) and Denver Developmental Screening Test II (DDST-II) in preterm babies with neurodevelopmental impairment, considering the detection rate as regulation of criteria. Methods: Retrospective medical chart reviews which included the Bayley-III and DDST-II, were conducted for 69 preterm babies. Detection rate of neurodevelopmental impairment in preterm babies were investigated by modulating scaled score of the Bayley-III...
October 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/29201824/assessment-of-preterm-infants-using-the-bayley-iii-scales-in-korea
#8
Sung Ho Ahn, Soo A Kim
Objective: To assess the well-being of preterm newborns using the Bayley-III scales in a Korean-based population, and to evaluate the perinatal risk factors influencing developmental outcome. Methods: Using the Bayley-III scales, we assessed 120 preterm infants who were referred for evaluation of neurodevelopmental performance. We subdivided them into an extremely preterm group (n=18) and a very/moderate to late preterm group (n=102). Bayley-III mean scores and the rate of infants showing a delay were compared for both groups...
October 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/29201074/worldwide-recall-rate-in-newborn-screening-programs-for-congenital-hypothyroidism
#9
REVIEW
Ladan Mehran, Davood Khalili, Shahin Yarahmadi, Atieh Amouzegar, Mehdi Mojarrad, Nasrin Ajang, Fereidoun Azizi
Context: Neonatal mass screening program for congenital hypothyroidism provides the best tool for prevention of its devastating effects on mental development. Despite the overall success of the screening programs in detecting congenital hypothyroidism and eliminating its sequelae and new developments made in the program design, high recall rate and false positive results impose a great challenge worldwide. Lower recall rate and false positive results may properly organize project expenses by reducing the unnecessary repeated laboratory tests, increase physicians and parents' assurance and cooperation, as well as reduce the psychological effects in families...
July 2017: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29194486/cortical-auditory-evoked-responses-in-preterm-neonates-revisited-by-spectral-and-temporal-analyses
#10
A Kaminska, V Delattre, J Laschet, J Dubois, M Labidurie, A Duval, A Manresa, J-F Magny, S Hovhannisyan, M Mokhtari, L Ouss, A Boissel, L Hertz-Pannier, M Sintsov, M Minlebaev, R Khazipov, C Chiron
Characteristic preterm EEG patterns of "Delta-brushes" (DBs) have been reported in the temporal cortex following auditory stimuli, but their spatio-temporal dynamics remains elusive. Using 32-electrode EEG recordings and co-registration of electrodes' position to 3D-MRI of age-matched neonates, we explored the cortical auditory-evoked responses (AERs) after 'click' stimuli in 30 healthy neonates aged 30-38 post-menstrual weeks (PMW). (1) We visually identified auditory-evoked DBs within AERs in all the babies between 30 and 33 PMW and a decreasing response rate afterwards...
August 11, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/29193647/the-incidence-characteristics-managements-and-outcomes-of-anaphylaxis-in-pregnancy-a-population-based-descriptive-study
#11
Stephen J McCall, Kathryn J Bunch, Peter Brocklehurst, Rhiannon D'Arcy, Kim Hinshaw, Jennifer J Kurinczuk, D Nuala Lucas, Benjamin Stenson, Derek Tuffnell, Marian Knight
OBJECTIVE: The aim of this study was to estimate the incidence of anaphylaxis in pregnancy and describe the management and outcomes in the UK. DESIGN: A population based descriptive study using the UK Obstetric Surveillance System(UKOSS). SETTING: All consultant-led maternity units in the UK. POPULATION: All pregnant women who had anaphylaxis between 1st October 2012 and 30th September 2015. Anaphylaxis was defined as a severe, life-threatening generalised or systemic hypersensitivity reaction...
November 29, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29191292/long-term-childhood-outcomes-after-interventions-for-prevention-and-management-of-preterm-birth
#12
REVIEW
Sarah R Murray, Sarah J Stock, Jane E Norman
Globally, preterm birth rates are rising and have a significant impact on neonatal morbidity and mortality. Preterm birth remains difficult to prevent and a number of strategies for preterm birth prevention (progesterone, cervical pessaries, cervical cerclage, tocolytics, and antibiotics) have been identified. While some of these show more promise, there is a paucity of evidence regarding the long-term effects of these strategies on childhood outcomes. Strategies used to improve the health of babies if born preterm, such as antenatal magnesium sulfate for fetal neuroprotection and antenatal corticosteroids for fetal lung maturation, show evidence of short-term benefit but lack large-scale follow-up data of long-term childhood outcomes...
December 2017: Seminars in Perinatology
https://www.readbyqxmd.com/read/29188651/-research-progress-on-the-relationship-and-mechanisms-between-periodontal-disease-and-preterm-birth-and-low-birth-weight-infants
#13
Wu Wanhong, Ye Changchang, Huang Ping
Preterm birth (PB) is defined as the birth of a baby less than 37 weeks of gestational age. Low birth weight (LBW) is defined as a newborn baby's weight of less than 2 500 g. PB is often accompanied by LBW. Preterm low birth weight (PLBW) is the leading cause of newborn deaths. Periodontal disease (PD) is a chronic oral infectious disease, and it is closely related with general health. Epidemiological data show that PD is a risk factor for PLBW and other adverse pregnancy outcomes. The possible mechanisms include the direct effects of periodontal bacteria, inflammatory reactions, and immune response; however, the exact pathogenetic mechanism involved remains controversial...
October 1, 2017: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/29187842/low-microbial-diversity-and-abnormal-microbial-succession-is-associated-with-necrotizing-enterocolitis-in-preterm-infants
#14
Priscila T Dobbler, Renato S Procianoy, Volker Mai, Rita C Silveira, Andréa L Corso, Bruna S Rojas, Luiz F W Roesch
Despite increased efforts, the diverse etiologies of Necrotizing Enterocolitis (NEC) have remained largely elusive. Clinical predictors of NEC remain ill-defined and currently lack sufficient specificity. The development of a thorough understanding of initial gut microbiota colonization pattern in preterm infants might help to improve early detection or prediction of NEC and its associated morbidities. Here we compared the fecal microbiota successions, microbial diversity, abundance and structure of newborns that developed NEC with preterm controls...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29185123/is-timing-of-enrollment-associated-with-birth-outcomes-findings-from-a-healthy-start-program-in-kansas
#15
Kyrah K Brown, Candace Johnson, Michele Spainhower, Nicole Fox Phillips, J'Vonnah Maryman
Objective The Sedgwick County Healthy Babies Healthy Start (HBHS) program provides community-based services (including care coordination, interconception care and home visiting) aimed at reducing racial/ethnic disparities in poor birth outcomes. The purpose of this study is to assess the effectiveness of the Sedgwick County HBHS program by comparing the birth outcomes of program participants who enrolled prenatally and those who did not participate while pregnant. Methods In this retrospective cohort study, we used data drawn from the Sedgwick County HBHS program...
November 28, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/29184005/an-infant-with-congenital-rubella-syndrome-in-developing-india
#16
Ajit Singh, Sharon Narula, Hashir Kareem, Tom Devasia
Congenital rubella syndrome (CRS), caused by rubella virus infection during pregnancy, remains a public health concern in developing countries. Three to five per cent of all suspected CRS cases in India have been proven to be a rubella infection. Only about 45%-60% of pregnant women and infants in India receive the rubella vaccination. We present a case of a preterm female infant who tested positive for the rubella virus. The baby was born with low birth weight and, on examination, showed pallor and hepatosplenomegaly...
November 28, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29183399/evaluating-progestogens-for-prevention-of-preterm-birth-international-collaborative-epppic-individual-participant-data-ipd-meta-analysis-protocol
#17
Lesley A Stewart, Mark Simmonds, Lelia Duley, Kristina Charlotte Dietz, Melissa Harden, Alex Hodkinson, Alexis Llewellyn, Sahar Sharif, Ruth Walker, Kath Wright
BACKGROUND: Preterm birth is the most common cause of death and harm to newborn babies. Babies that are born early may have difficulties at birth and experience health problems during early childhood. Despite extensive study, there is still uncertainty about the effectiveness of progestogen (medications that are similar to the natural hormone progesterone) in preventing or delaying preterm birth, and in improving birth outcomes. The Evaluating Progestogen for Prevention of Preterm birth International Collaborative (EPPPIC) project aims to reduce uncertainty about the specific conditions in which progestogen may (or may not) be effective in preventing or delaying preterm birth and improving birth outcomes...
November 28, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/29181841/epidural-therapy-for-the-treatment-of-severe-pre-eclampsia-in-non-labouring-women
#18
REVIEW
Amita Ray, Sujoy Ray
BACKGROUND: Pre-eclampsia is a pregnancy-specific multi-organ disorder, which is characterised by hypertension and multisystem organ involvement and which has significant maternal and fetal morbidity and mortality. Failure of the placental vascular remodelling and reduced uteroplacental flow form the etiopathological basis of pre-eclampsia. There are several established therapies for pre-eclampsia including antihypertensives and anticonvulsants. Most of these therapies aim at controlling the blood pressure or preventing complications of elevated blood pressure, or both...
November 28, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29180840/candida-chorioamnionitis-leads-to-preterm-birth-and-adverse-fetal-neonatal-outcome
#19
REVIEW
Yohei Maki, Midori Fujisaki, Yuichiro Sato, Hiroshi Sameshima
Candida chorioamnionitis is rare but can lead to neonatal infection, high mortality, and neurodevelopmental impairment. We aimed to investigate maternal clinical features and perinatal outcomes and discuss future management strategies. We reviewed the medical records of women with Candida chorioamnionitis at our hospital over a 10-year period (n = 9) and previous published case reports and case series. The most prevalent Candida species was C. albicans (71.3% of the all cases). The most prevalent predisposing condition was preterm premature rupture of membranes (31/123, 25...
2017: Infectious Diseases in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29166874/efficacy-and-safety-of-pertussis-vaccination-for-pregnant-women-a-systematic-review-of-randomised-controlled-trials-and-observational-studies
#20
Marie Furuta, Jacqueline Sin, Edmond S W Ng, Kay Wang
BACKGROUND: Worldwide, pertussis remains a major health problem among children. During the recent outbreaks of pertussis, maternal antenatal immunisation was introduced in several industrial countries. This systematic review aimed to synthesize evidence for the efficacy and safety of the pertussis vaccination that was given to pregnant women to protect infants from pertussis infection. METHODS: We searched literature in the Cochrane Central Register of Controlled Trials, Medline, Embase, and OpenGrey between inception of the various databases and 16 May 2016...
November 22, 2017: BMC Pregnancy and Childbirth
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