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Industrial pulmonary function test

Ke Yang, Jiandong Wu, Hagit Peretz-Soroka, Ling Zhu, Zhigang Li, Yaoshuo Sang, Jolly Hipolito, Michael Zhang, Susy Santos, Craig Hillier, Ricardo Lobato de Faria, Yong Liu, Francis Lin
Mobile sensing based on the integration of microfluidic device and smartphone, so-called MS(2) technology, has enabled many applications over recent years, and continues to stimulate growing interest in both research communities and industries. In particular, it has been envisioned that MS(2) technology can be developed for various cell functional assays to enable basic research and clinical applications. Toward this direction, in this paper, we describe the development of a MS(2)-based cell functional assay for testing cell migration (the Mkit)...
January 15, 2018: Biosensors & Bioelectronics
Iain Simpson
This Industry Update covers the period from 1 through 30 April 2017, and is based on information sourced from company press releases, scientific literature, patents and various news websites. Biogen expanded its portfolio of developmental drugs targeting neurological diseases by licensing a drug from Bristol-Myers Squibb which is currently under investigation for the treatment of progressive supranuclear palsy. Takeda announced a deal with NuBiyota focused on developing treatments for gastrointestinal disorders, based on the manipulation of microbes living in the gut...
July 2017: Therapeutic Delivery
Hamzeh Mohammadi, Somayeh Farhang Dehghan, Farideh Golbabaei, Saman Roshani, Reza Pakzad, Parvin Foroughi, Roohalah Hajizadeh
BACKGROUND: This study aimed to investigate the pulmonary functions of silica-exposed workers and their health-related quality of life in an insulator manufacturing industry. MATERIALS AND METHODS: In this cross-sectional study, participants selected from the manufacturing unit (n = 127) constituted the exposed group and those from the administrative department (n = 30) constituted the unexposed group. All subjects were evaluated using personal air sampling of crystalline silica, pulmonary function tests, and a quality of life questionnaire (36-item short form health survey [SF-36])...
2017: Tanaffos
Bharat M Dangi, Anjali R Bhise
BACKGROUND: Cotton industry workers are exposed to various hazards in the different departments of textile factories. The major health problems associated with cotton dust are respiratory problems, byssinosis, bronchitis and asthma. OBJECTIVE: To study the effect of cotton dust exposure on pulmonary function and respiratory symptoms. SETTINGS AND DESIGN: This cross-sectional observational study was conducted at cotton mill in the Ahmedabad city...
March 2017: Lung India: Official Organ of Indian Chest Society
Murat Acat, Yusuf Aydemir, Onur Yazıcı, Mahmut Turğut, Mustafa Çörtük, Murat Çakar, Zehra Yaşar, Sami Deniz, Erdoğan Çetinkaya
Objectives. Exposure to ambient metals and air pollutants in urban environments has been associated with impaired lung health and inflammation in the lungs. Fractional exhaled nitric oxide (FeNO) is a reliable marker of airway inflammation. In this study, we aimed to compare the FeNO levels of three schools that have different distances from iron and steel industry zone for assessing the effects of heavy metals and air pollution on their respiratory health. Methods. Pulmonary function test and FeNO measurements were evaluated in 387 adolescents in three schools which have different distance from plant...
2017: Canadian Respiratory Journal: Journal of the Canadian Thoracic Society
Richa Mittal, Pawan Gupta, Sunil K Chhabra
The most well-known disease caused by cotton dust is byssinosis though it is also associated with chronic obstructive airways disease, and very rarely, interstitial lung disease. Obliterative bronchiolitis has never been reported in this setting. We report a 63-year-old, nonsmoker male, who presented with complaints of cough and exertional dyspnoea for 10 years. He had worked in textile industry for 35 years and symptoms had persisted even after quitting. Examination revealed prolonged expiration with expiratory wheeze, and pulmonary function tests revealed severe airflow limitation with air trapping and impaired diffusion capacity...
May 2016: Indian Journal of Occupational and Environmental Medicine
R Sitalakshmi, P Saikumar, P Jeyachandran, Manoharan, Thangavel, Jayakar Thomas
BACKGROUND: Construction industry is the second largest employment giving industry in India with many semi-skilled or unskilled workers taking up the occupation for livelihood without any training and proper guidance. AIM: To evaluate the pathogenic association of cement exposure to occupational contact dermatoses as evidenced by immune markers and to correlate their pulmonary functions with years of exposure to cement. SETTING AND DESIGN: This was a cross-sectional study conducted among randomly selected cement workers...
May 2016: Indian Journal of Occupational and Environmental Medicine
Ioannis D Anyfantis, Georgios Rachiotis, Cristos Hadjichristodoulou, Konstantinos I Gourgoulianis
BACKGROUND: Workers in cotton industry are occupationally exposed to various dust-related hazards. The nature of these agents and the respective exposure levels depend on the cotton industry specific sector. These exposures could be associated with respiratory symptoms and changes in lung function parameters. OBJECTIVE: To evaluate associations between occupational exposure and respiratory function as well as reported symptoms in several groups of workers at different stages of the cotton industry in a vertical approach that covers all the major sectors-from cotton ginning to weaving and fabric production...
January 2017: International Journal of Occupational and Environmental Medicine
Qing-Zeng Qian, Xiang-Ke Cao, Fu-Hai Shen, Qian Wang
The present study aimed to investigate the correlation of smoking with cumulative total dust exposure (CTE) and cumulative abnormal rate of pulmonary function in coal-mine workers. A total of 376 coal-mine workers were recruited as the observational group, while 179 healthy workers in other industries were selected as the control group. All the workers underwent pulmonary function testing to determine their forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1) and FEV1/FVC, in order to compare the abnormal pulmonary function between the two groups...
November 2016: Experimental and Therapeutic Medicine
Carla Valenti, Paolo Pozzi, Alessandra Busia, Roberto Mazza, Paolo Bossi, Cinzia De Marco, Ario Alberto Ruprecht, Alessandro Borgini, Roberto Boffi
BACKGROUND: This report is based on an independent study carried out by medical professionals of the Fondazione IRCCS Istituto Nazionale dei Tumori (National Cancer Institute) in Milan, Italy, and  aimed to assess the incidence of respiratory diseases in a Brazilian community (Piquiá de Baixo, in the city of Açailandia) exposed to extreme air pollution in connection to a local steel manufacturing plant. The study has the objective to contribute to the existing literature on the health risks associated with fine particle pollution (PM2...
2016: Multidisciplinary Respiratory Medicine
Chan Yeu Pu, Mohamed Rizwan Haroon Al Rasheed, Marin Sekosan, Vibhu Sharma
A 61-year-old man was evaluated for a 2 month history of cough and dyspnea without relevant exposures other than pyrethrin containing insecticidal sprays he used while grooming dogs almost daily. High Resolution Computed Tomography (HRCT) of the chest demonstrated a Non-Specific Interstitial Pneumonia (NSIP) pattern. Pulmonary function testing revealed an isolated mildly reduced diffusion capacity. Bronchoalveolar lavage (BAL) results confirmed the presence of foamy histiocytes, lymphocytes, and polymorphonuclear cells consistent with ongoing exposure...
January 2017: American Journal of Industrial Medicine
Inéz Frerichs, Marcelo B P Amato, Anton H van Kaam, David G Tingay, Zhanqi Zhao, Bartłomiej Grychtol, Marc Bodenstein, Hervé Gagnon, Stephan H Böhm, Eckhard Teschner, Ola Stenqvist, Tommaso Mauri, Vinicius Torsani, Luigi Camporota, Andreas Schibler, Gerhard K Wolf, Diederik Gommers, Steffen Leonhardt, Andy Adler
Electrical impedance tomography (EIT) has undergone 30 years of development. Functional chest examinations with this technology are considered clinically relevant, especially for monitoring regional lung ventilation in mechanically ventilated patients and for regional pulmonary function testing in patients with chronic lung diseases. As EIT becomes an established medical technology, it requires consensus examination, nomenclature, data analysis and interpretation schemes. Such consensus is needed to compare, understand and reproduce study findings from and among different research groups, to enable large clinical trials and, ultimately, routine clinical use...
January 2017: Thorax
Nadia Ghani, Anum Khalid, Arifa Tahir
OBJECTIVE: To examine the effects of airborne endotoxin on lung function impairment in exposure-response relationships among the workers of textile industry. METHODS: The cross-sectional study was conducted at Lahore College for Women University, Lahore, Pakistan, from January to August 2014, and comprised textile mill workers. The participants were divided into exposed and control groups. A questionnaire was used to ask workers about the potential adverse health effects of their occupation...
July 2016: JPMA. the Journal of the Pakistan Medical Association
S Kumar, F Khaliq, S Singh, R Ahmed, R Kumar, P S Deshmukh, B D Banerjee
BACKGROUND: Occupational exposure to excessive level of copper results in many adverse health effects. OBJECTIVE: To measure pulmonary function, oxidative stress, and extent of DNA damage in workers of a copper processing industry. METHODS: 30 men working in a copper processing industry and 30 men matched for age and socioeconomic status (comparison group) were included in this study. Pulmonary function test parameters were measured for all participants...
April 2016: International Journal of Occupational and Environmental Medicine
Mônica Vasconcelos de Moraes, Rosimeire Simprini Padula, Rosane Andrea Bretas Bernardes, Alexandher Negreiros, Luciana Dias Chiavegato
[Purpose] This cross-sectional study aimed to compare foundry workers of the metallurgical industry with high and low exposure time and with a control group. [Subject and Methods] The workers were evaluated for pulmonary function and peak expiratory flow (PEF), respiratory symptoms, smoking habits, and physical activity level. Descriptive statistical analysis and ANOVA one-way test were used. [Results] The mean age was 33.9 ± 8.25 years (18-59), pulmonary function: FVC: 95 ± 18% of predicted, FEV1: 95.0 ± 15...
January 2016: Journal of Physical Therapy Science
Adam W Gaffney, Jing-qing Hang, Mi-Sun Lee, Li Su, Feng-ying Zhang, David C Christiani
BACKGROUND: An inverse association between socioeconomic status and pulmonary function has emerged in many studies. However, the mediating factors in this relationship are poorly understood, and might be expected to differ between countries. We sought to investigate the relationship between socioeconomic status and lung function in China, a rapidly industrializing nation with unique environmental challenges, and to identify potentially-modifiable environmental mediators. METHODS: We used data from the Shanghai Putuo Study, a cross-sectional study performed in Shanghai, China...
2016: BMC Public Health
Azam F Tayabali, Gordon Coleman, Kathy C Nguyen
Pseudomonas species are opportunistically pathogenic to humans, yet closely related species are used in biotechnology applications. In order to screen for the pathogenic potential of strains considered for biotechnology applications, several Pseudomonas strains (P.aeruginosa (Pa), P.fluorescens (Pf), P.putida (Pp), P.stutzeri (Ps)) were compared using functional virulence and toxicity assays. Most Pa strains and Ps grew at temperatures between 28°C and 42°C. However, Pf and Pp strains were the most antibiotic resistant, with ciprofloxacin and colistin being the most effective of those tested...
2015: PloS One
Ehsan Rafeemanesh, Ashkan Alizadeh, Lahya Afshari Saleh, Hosein Zakeri
BACKGROUND: The respiratory system is the most vulnerable system in the cement industry. This study was conducted to determine the effects of occupational exposure to cement dust on the respiratory system more thoroughly. MATERIAL AND METHODS: In this cross sectional study an interviewer-administered questionnaire on socio-demographic characteristics and respiratory symptoms was completed and pulmonary function tests were carried out on 100 exposed and 120 non-exposed workers at the cement factory in Mashhad, Iran...
2015: Medycyna Pracy
Omid Aminian, Hamidreza Zeinodin, Khosro Sadeghniiat-Haghighi, Nazanin Izadi
BACKGROUND: Galvanization is the process of coating steel or cast iron pieces with a thin layer of zinc allowing protection against corrosion. One of the important hazards in this industry is exposure to zinc compounds specially zinc oxide fumes and dusts. In this study, we evaluated chronic effects of zinc oxide on the respiratory tract of galvanizers. METHODS: Overall, 188 workers were selected from Arak galvanization plant in 2012, 71 galvanizers as exposed group and 117 workers from other departments of plants as control group...
2015: Journal of Research in Health Sciences
Masoud Nazemiyeh, Akbar Sharifi, Farhad Amiran, Leili Pourafkari, Mohammadreza Taban Sadeghi, Hossein Namdar, Mohsen Abbasnezhad
INTRODUCTION: Congestive heart failure (CHF) is a common disease and its prevalence is increasing in industrialized countries. NT-proBNP measurement is an established diagnostic test for diagnosis of CHF in patients who present to emergency room with acute dyspnea. The primary object of this study was to determine the relationship between levels of brain natriuretic peptide precursor and severity of lung function impairment in patients with chronic CHF. METHODS: This cross-sectional and analytical study that performed in Tuberculosis and Lung Disease Research Center of Tabriz University of Medical Sciences on 95 patients with chronic heart failure, and relation between NT-proBNP levels and pulmonary function parameters were examined...
2015: Journal of Cardiovascular and Thoracic Research
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