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Ear infections

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https://www.readbyqxmd.com/read/29472155/the-wifi-otoplasty-combined-concentric-posterior-microchondrectomies-and-sutures-for-correction-of-prominent-ears
#1
Benoit I M M Hendrickx, Moustapha Hamdi, Assaf Zeltzer, Andrew Greensmith
BACKGROUND: Prominent ears are by far the most common congenital ear deformity. Many techniques have been described using one or a combination of 3 basic methods: cartilage cutting, cartilage weakening and pure cartilage shaping techniques. The ideal otoplasty technique should yield a natural correction of the deformity, with low recurrence rates and with little risk of complications. METHODS: A new cartilage shaping technique using closing wedge concentric microchondrectomies through an entirely posterior approach is presented...
February 19, 2018: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/29468490/negative-pressure-wound-therapy-reduces-the-motility-of-pseudomonas-aeruginosa-and-enhances-wound-healing-in-a-rabbit-ear-biofilm-infection-model
#2
Wang Guoqi, Li Zhirui, Wang Song, Li Tongtong, Zhang Lihai, Zhang Licheng, Tang Peifu
Pseudomonas aeruginosa motility, virulence factors and biofilms are known to be detrimental to wound healing. The efficacy of negative pressure wound therapy (NPWT) against P. aeruginosa has been little studied, either in vitro or in vivo. The present study evaluated the effect of negative pressure (NP) on P. aeruginosa motility in vitro, and the effect of NPWT on virulence factors and biofilms in vivo. P. aeruginosa motility was quantified under different levels of NP (atmospheric pressure, - 75, - 125, - 200 mmHg) using an in vitro model...
February 21, 2018: Antonie Van Leeuwenhoek
https://www.readbyqxmd.com/read/29467751/photodynamic-vaccination-of-balb-c-mice-for-prophylaxis-of-cutaneous-leishmaniasis-caused-by-leishmania-amazonensis
#3
Sayonara M Viana, Fabiana S Celes, Laura Ramirez, Bala Kolli, Dennis K P Ng, Kwang P Chang, Camila I de Oliveira
Background: Photosensitizers (PS), like porphyrins and phthalocyanines (PC) are excitable by light to generate cytotoxic singlet oxygen and other reactive oxygen species in the presence of atmospheric O2 . Photodynamic inactivation of Leishmania by this means renders them non-viable, but preserves their effective use as vaccines. Leishmania can be photo-inactivated after PS-sensitization by loading via their endocytic uptake of PC or endogenous induction of transgenic mutants with delta-aminolevulinate (ALA) to accumulate cytosolic uroporphyrin I (URO)...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29464160/earfold-implantable-clip-system-for-correction-of-prominent-ears-analysis-of-safety-in-403-patients
#4
Norbert V Kang, Nilesh Sojitra, Sinisa Glumicic, Jacobus A Vlok, Greg O'Toole, S Alam Hannan, Walid Sabbagh
Background: The Earfold system, a new treatment for the correction of prominent ears, consists of 3 components: the Earfold implant, the Earfold introducer, and the Prefold positioner. Methods: This is an interim report based on an ongoing analysis of safety in a series of patients treated for prominent ears with the Earfold implant between February 2013 and September 2014. Safety was assessed based on adverse event reports and the need for implant revision; follow-up is ongoing...
January 2018: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/29458340/a-microbiome-case-control-study-of-recurrent-acute-otitis-media-identified-potentially-protective-bacterial-genera
#5
Rachael Lappan, Kara Imbrogno, Chisha Sikazwe, Denise Anderson, Danny Mok, Harvey Coates, Shyan Vijayasekaran, Paul Bumbak, Christopher C Blyth, Sarra E Jamieson, Christopher S Peacock
BACKGROUND: Recurrent acute otitis media (rAOM, recurrent ear infection) is a common childhood disease caused by bacteria termed otopathogens, for which current treatments have limited effectiveness. Generic probiotic therapies have shown promise, but seem to lack specificity. We hypothesised that healthy children with no history of AOM carry protective commensal bacteria that could be translated into a specific probiotic therapy to break the cycle of re-infection. We characterised the nasopharyngeal microbiome of these children (controls) in comparison to children with rAOM (cases) to identify potentially protective bacteria...
February 20, 2018: BMC Microbiology
https://www.readbyqxmd.com/read/29456946/detection-of-epstein-barr-and-human-papilloma-viruses-in-the-middle-ear-squamous-cell-carcinoma
#6
Agus Surono, Bambang Hariwiyanto, Edhie Samodra
The uncommon ear tumor of middle ear squamous cell carcinoma (MESCC) is thought to be associated with the history of long-term chronic otitis media in the most cases. The main etiologic factor of MESCC is still unclear and may be multifactorial. Infections of Epstein-Barr virus (EBV) and Human Papillomavirus (HPV) are considered as one of the etiologic factor of MESCC. Previous studies have shown that the EBV and HPV have been detected in MESCC. Although the EBV and HPV have been implicated in human malignancies, their roles in pathogenesis of MESCC have not been elucidated...
March 2018: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/29456562/colonization-with-hospital-flora-and-its-associated-risk-factors-in-neonates-hospitalized-in-neonatal-ward-of-a-teaching-center-in-isfahan-iran
#7
Kiana Shirani, Kamyar Mostafavizadeh, Behrouz Ataei, Khatere Akhani
Background: Due to the high incidence and prevalence of infection in neonatal ward, especially Neonatal Intensive Care Units (NICUs) reported by different studies and the important role of colonization with hospital germs in the development of nosocomial infections, we intended to evaluate the risk of colonization with hospital germs in neonates and its associated risk factors. Materials and Methods: This cross-sectional, descriptive-analytical study was conducted in 2016 in a Teaching Center in Iran...
2018: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/29453208/parent-reported-prevalence-and-persistence-of-19-common-child-health-conditions
#8
Tracy Liu, Raghu Lingam, Kate Lycett, Fiona K Mensah, Joshua Muller, Harriet Hiscock, Md Hamidul Huque, Melissa Wake
OBJECTIVE: To estimate prevalence and persistence of 19 common paediatric conditions from infancy to 14-15 years. DESIGN: Population-based prospective cohort study. SETTING: Australia. PARTICIPANTS: Parallel cohorts assessed biennially from 2004 to 2014 from ages 0-1 and 4-5 years to 10-11 and 14-15 years, respectively, in the Longitudinal Study of Australian Children. MAIN OUTCOME MEASURES: 19 health conditions: 17 parent-reported, 2 (overweight/obesity, obesity) directly assessed...
February 16, 2018: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29450387/orbital-cellulitis-and-brain-abscess-rare-complications-of-maxillo-spheno-ethmoidal-rhinosinusitis
#9
Farah Constantin, Patricia-Alexandra Niculescu, Oana Petre, Daniel Balasa, Alexandru Tunas, Ioana Rusu, Mihai Lupascu, Cristiana Orodel
Sinus infections can be complicated by ocular infections and, in late phases, by brain parenchyma infection. The article debates the case of a 12-year-old patient suffering from paucisymptomatic maxillo-spheno-ethmoidal rhinosinusitis, which was later complicated by orbital cellulitis, ending with the development of a brain abscess. The treatment is complex, initially targeting the source of the infection through draining the collection by middle maxillary antrostomy and anterior posterior ethmoidectomy, then the ablation of the brain abscess and postoperatively with prolonged massive antibiotherapy...
April 2017: Romanian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29447884/knowledge-and-attitudes-of-early-childhood-development-practitioners-towards-hearing-health-in-poor-communities
#10
Shouneez Yousuf Hussein, De Wet Swanepoel, Leigh Biagio de Jager, Faheema Mahomed-Asmail
OBJECTIVE: Within the educational sector of low-and middle-income countries (LMICs), formal and informal early childhood development (ECD) centers are often the first point of contact for majority of children. Since early hearing detection services are mostly absent in LMICs, these ECD centers may serve as the first point of access to screenings for these children. ECD practitioner awareness regarding hearing and hearing loss is essential for the successful implementation of hearing screening programs...
March 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29446785/effects-of-salso-bromo-iodine-thermal-water-in-children-suffering-from-otitis-media-with-effusion-a-randomized-controlled-pilot-study
#11
I La Mantia, C Andaloro
BACKGROUND: Otitis media with effusion (OME) is an ear disorder defined by the presence of fluid in the middle ear without signs or symptoms of acute infection. The aim of this randomised and controlled pilot study was to evaluate whether the treatment with a watery salsobromo- iodine solution, administered by nasal douche, could induce ear healing better than isotonic saline in children with OME. METHODS: The study was randomized, single-blind, and controlled. Study group (40 children) was treated with salso-bromo-iodine thermal water solution and Control group (40 children) was treated with isotonic saline; both compounds were administered by nasal nebulization with Rinowash nasal douche twice/day for 10 days a month for 3 consecutive months...
January 2018: La Clinica Terapeutica
https://www.readbyqxmd.com/read/29445729/-brucella-antibodies-in-alaskan-true-seals-and-eared-seals-two-different-stories
#12
Ingebjørg H Nymo, Rolf Rødven, Kimberlee Beckmen, Anett K Larsen, Morten Tryland, Lori Quakenbush, Jacques Godfroid
Brucella pinnipedialis was first isolated from true seals in 1994 and from eared seals in 2008. Although few pathological findings have been associated with infection in true seals, reproductive pathology including abortions, and the isolation of the zoonotic strain type 27 have been documented in eared seals. In this study, a Brucella enzyme-linked immunosorbent assay (ELISA) and the Rose Bengal test (RBT) were initially compared for 206 serum samples and a discrepancy between the tests was found. Following removal of lipids from the serum samples, ELISA results were unaltered while the agreement between the tests was improved, indicating that serum lipids affected the initial RBT outcome...
2018: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/29436578/protective-effect-of-adenovirus-mediated-erythropoietin-expression-on-the-spiral-ganglion-neurons-in-the-rat-inner-ear
#13
Cheng Zhong, Zhendong Jiang, Qiang Guo, Xueyuan Zhang
The aim of the present study was to evaluate the expression of erythropoietin (Epo) and the Epo receptor (Epo‑R) in the spiral ganglion neurons (SGNs) of the rat inner ear, and to assess the effect of Epo adenovirus vector (Ad‑Epo) on the spontaneous apoptosis of SGNs. A total of 60 ears from 30 healthy neonatal (2‑3 days postnatal) Sprague‑Dawley rats were used to examine the expression of Epo in the SGNs. The rats were divided into three groups: The negative control group, the vector control group [infected with a green fluorescent protein expression vector (Ad‑GFP)] and the Ad‑Epo group (infected with Ad‑Epo)...
February 5, 2018: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/29429025/risk-factors-for-complications-in-cochlear-implant-surgery
#14
Henricus J Theunisse, Ronald J E Pennings, Henricus P M Kunst, Jef J Mulder, Emmanuel A M Mylanus
PURPOSE: The objective of this study was to achieve uniform reporting of complications and failures in cochlear implantation, to analyze complications and failures and to identify risk factors for complications in a series of over 1300 cochlear implantations. METHODS: In a retrospective chart review and observational study, data from all cochlear implantations from 1987 to 2015 were entered in a custom-made database. Complications were classified using the contracted form of the Clavien-Dindo system and risk factors were identified by statistical analysis...
February 10, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29426290/transcriptome-profiling-of-two-maize-inbreds-with-distinct-responses-to-gibberella-ear-rot-disease-to-identify-candidate-resistance-genes
#15
Aida Z Kebede, Anne Johnston, Danielle Schneiderman, Whynn Bosnich, Linda J Harris
BACKGROUND: Gibberella ear rot (GER) is one of the most economically important fungal diseases of maize in the temperate zone due to moldy grain contaminated with health threatening mycotoxins. To develop resistant genotypes and control the disease, understanding the host-pathogen interaction is essential. RESULTS: RNA-Seq-derived transcriptome profiles of fungal- and mock-inoculated developing kernel tissues of two maize inbred lines were used to identify differentially expressed transcripts and propose candidate genes mapping within GER resistance quantitative trait loci (QTL)...
February 9, 2018: BMC Genomics
https://www.readbyqxmd.com/read/29423745/in-reply-to-commentary-to-endoscopic-and-clinical-benefits-of-hyaluronic-acid-in-children-with-chronic-adenoiditis-and-middle-ear-disease-by-zhengcai-lou
#16
S Torretta, P Marchisio, V Rinaldi, D Carioli, E Nazzari, L Pignataro
Some considerations will be expressed in consideration of the commentary previously published. In particular, we underline that no other medications were administered to the patients during the study period and any clinical evaluation was postponed in case of acute upper respiratory tract infection in the previous 14 days. We strongly advocate antibiotic treatment during any acute otitis media episode, and we agree that topically administered hyaluronic acid should be considered as a supporting treatment, "complementary to traditional therapies" in children with recurrent disease...
February 8, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29419592/refinements-in-elevation-of-the-reconstructed-auricle-the-zigzag-incision
#17
So-Eun Han, Yeseul Eom, Kap Sung Oh
OBJECTIVE: Auricular elevation with superficial temporal fascia and skin graft is widely used in microtia reconstruction using costal cartilage. However, in some patients, there has been occurrence of contraction of skin graft, which led to insufficient projection of the elevated auricle and diminished auriculocephalic angle with unfavorable long-term results. In this article, the authors introduce their multiple triangular flaps with zigzag incision to maintain stable projection and natural retroauricular sulcus appearance in auricular reconstruction patients...
February 6, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29415430/mexican-propolis-a-source-of-antioxidants-and-anti-inflammatory-compounds-and-isolation-of-a-novel-chalcone-and-%C3%AE%C2%B5-caprolactone-derivative
#18
Silvia Laura Guzmán-Gutiérrez, Antonio Nieto-Camacho, Jorge Ivan Castillo-Arellano, Elizabeth Huerta-Salazar, Griselda Hernández-Pasteur, Mayra Silva-Miranda, Omar Argüello-Nájera, Omar Sepúlveda-Robles, Clara Inés Espitia, Ricardo Reyes-Chilpa
The propolis produced by bees are used in alternative medicine for treating inflammation, and infections, presumably due to its antioxidant properties. In this context, five propolis from México were investigated to determine their inhibitory lipid peroxidation properties. The ethyl acetate extract from a red propolis from Chiapas State (4-EAEP) was the most potent (IC50 = 1.42 ± 0.07 μg/mL) in the TBARS assay, and selected for further studies. This extract afforded two new compounds, epoxypinocembrin chalcone ( 6 ), and an ε-caprolactone derivative ( 10 ), as well as pinostrobin ( 1 ), izalpinin ( 2 ), cinnamic acid ( 3 ), pinocembrin ( 4 ), kaempherol ( 5 ), 3,3-dimethylallyl caffeate in mixture with isopent-3-enyl caffeate ( 7a + 7b ), 3,4-dimethoxycinnamic acid ( 8 ), rhamnetin ( 9 ) and caffeic acid ( 11 )...
February 6, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29408507/have-the-recent-modifications-of-operating-room-attire-policies-decreased-surgical-site-infections-a-nsqip-review-of-6-517-patients
#19
Sandra M Farach, Kristin N Kelly, Rachel L Farkas, Daniel T Ruan, Amy Matroniano, David C Linehan, Jacob Moalem
BACKGROUND: After a Department of Health site visit, 2 teaching hospitals imposed strict regulations on operating room attire including full coverage of ears and facial hair. We hypothesized that this intervention would reduce superficial surgical site infections (SSI). STUDY DESIGN: We compared NSQIP data from all patients undergoing surgery in the 9 months before implementation (n=3,077) to time-matched data 9 months post-implementation (n=3,440). Univariate and multivariable analyses were used to examine patient, clinical, and operative factors associated with SSI...
February 2, 2018: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/29404836/characterization-of-the-nasopharyngeal-and-middle-ear-microbiota-in-gastroesophageal-reflux-prone-versus-gastroesophageal-reflux-non-prone-children
#20
Stefan A Boers, Marjolein de Zeeuw, Ruud Jansen, Marc P van der Schroeff, Annemarie M C van Rossum, John P Hays, Suzanne J C Verhaegh
Otitis media (OM) is one of the most common pediatric infections worldwide, but the complex microbiology associated with OM is poorly understood. Previous studies have shown an association between OM and gastroesophageal reflux (GER) in children. Therefore, in order to bridge the gap in our current understanding of the interaction between GER and OM, we investigated the nasopharyngeal and middle ear microbiota of children suffering from GER-associated OM and OM only, using culture-independent 16S rRNA gene sequencing...
February 5, 2018: European Journal of Clinical Microbiology & Infectious Diseases
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