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https://www.readbyqxmd.com/read/29925172/-effect-of-n-acetyl-l-cysteine-on-vascular-heterogeneity-of-microcirculation-in-endotoxemia-rabbits-and-its-mechanism
#1
B Yao, D W Liu, W Z Chai, X T Wang, H M Zhang
Objective: To study the effect of N-acetyl-L-cysteine (NAC) on vascular heterogeneity in microcirculation dysfunction caused by endotoxemia and its mechanism. Methods: Eighteen Japanese big ear rabbits were divided into three groups: Control group, Lipopolysaccharides (LPS) group and LPS+ NAC group.A dose of 2 mg/kg LPS was injected to set up endotoxemia rabbit models.Rabbits in the LPS+ NAC group were infused with NAC at a dose of 350 mg/kg, and the same amount of normal saline were infected intravenously to the rabbits in the Control and LPS group...
June 19, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29916767/development-of-an-ear-cap-in-chronic-suppurative-otitis-media-using-additive-manufacturing-and-triz
#2
Mahesh B Mawale, Abhaykumar Kuthe, Anupama M Mawale, Sandeep W Dahake
The prevalence rate of chronic suppurative otitis media is high and its treatment continues to be a challenge for the otorhinolaryngologists. Due to middle ear infection, there may be pain, hearing loss and spontaneous rupture of the eardrum which results in perforation. Infections can cause a hole in the eardrum as a side effect of otitis media. The patients suffering from ear perforation or having a hole in eardrum require preventing entry of water in the ear. This article describes the development of ear cap using additive manufacturing and TRIZ (a collaborative tool) to prevent the entry of water in the ear during chronic otitis media...
June 1, 2018: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/29914826/a-pilot-study-to-investigate-the-therapeutic-effect-of-valsalva-maneuver-on-otitis-media-with-effusion-in-adults
#3
Jung Ju Han, Jung Mee Park, Dong Kee Kim, So Young Park, Shi Nae Park
OBJECTIVE: This pilot study was performed to investigate the therapeutic effect of Valsalva maneuver on otitis media in adults and to evaluate the prognostic factors for the good response. METHODS: Thirty nine ears of 32 adult patients who were diagnosed as otitis media with effusion and managed by one-week Valsalva maneuver (>20/day) without any other medication were included in this study. Its therapeutic efficacy was evaluated and the prognostic factors which predict the response of Valsalva maneuver were analyzed by comparing various clinical and audiological factors between success and failure groups...
June 15, 2018: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29910617/acetaminophen-antibiotics-ear-infection-breastfeeding-vitamin-d-drops-and-autism-an-epidemiological-study
#4
Seth Scott Bittker, Kathleen Roberta Bell
Background: While many studies have examined environmental risk factors for autism spectrum disorder (ASD), much of the research focus has been on prenatal or perinatal factors. Yet, the postnatal environment may affect the risk of ASD as well. Objective: To determine whether a set of five postnatal variables are associated with ASD. These variables are: acetaminophen exposure, antibiotic exposure, incidence of ear infection, decreased duration of breastfeeding, and decreased consumption of oral vitamin D drops...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29907187/ticks-from-cats-in-the-united-states-patterns-of-infestation-and-infection-with-pathogens
#5
Susan E Little, Anne W Barrett, Yoko Nagamori, Brian H Herrin, Dorothy Normile, Kathleen Heaney, Rob Armstrong
Ticks are an important but under recognized parasitic threat to cats in many areas of the United States. To characterize the species and stages of ticks most commonly recovered from cats and determine the prevalence of disease agents in the ticks, we conducted a survey of ticks removed from cats at veterinary practices in 18 states from April 2016-June 2017. A total of 796 ticks were submitted from 332 cats from 41 different veterinary practices. A single tick was submitted from the majority of cats, with a mean infestation intensity of 2...
June 15, 2018: Veterinary Parasitology
https://www.readbyqxmd.com/read/29905059/-current-progress-of-laser-assisted-cartilage-reshaping-for-prominent-ear
#6
REVIEW
Fengfeng Guo, Xiaobo Yu, Haiyue Jiang
Objective: To summarize the current progress of laser-assisted cartilage reshaping (LACR) for prominent ear. Methods: The domestic and abroad article concerning the LACR in treatment of prominent ear was reviewed and analyzed. Results: As a new technique, there were three types of LACR therapies that been used for prominent ear. LACR with the 1 064 nm Nd/YAG laser is painful and the penetration depth of the 1 064 nm Nd/YAG laser is greater than that of the 1540 nm Er/Glass laser which is caused more tissue injury...
June 1, 2018: Chinese Journal of Reparative and Reconstructive Surgery
https://www.readbyqxmd.com/read/29904969/mucormycotic-parotitis-and-otitis-causing-facial-nerve-palsy-in-a-diabetic-patient
#7
Debasis Gochhait, Arun Alexender, Priyadarshini Dehuri, Vidhyalakshmi Rangarajan, Sajini Elizabeth Jacob, Neelaiah Siddaraju
Isolated invasive Mucormycosis of the parotid gland is rarely reported in the literature (1). Mucormycosis most commonly manifests as rhino-oculocerebral and pulmonary infections in the patients with altered immunity (uncontrolled Diabetes mellitus, recipients of immunosupressive therapy and underlying hematological malignancies) (2). Rarely, it causes infection in the immunocompetent individuals (3) with the involvement of unusual sites like gastrointestinal tract, ear, soft tissue and skin (4, 5). This article is protected by copyright...
June 15, 2018: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29891397/immediate-effects-of-a-rhino-pharyngeal-clearance-protocol-in-nasal-obstruction-and-middle-ear-condition-of-children-under-3-years-of-age-with-upper-respiratory-infections-a-randomized-controlled-trial
#8
Ana Silva Alexandrino, Rita Santos, Cristina Melo, David Tomé, José Mesquita Bastos, Guy Postiaux
INTRODUCTION AND OBJECTIVES: Children up to 2 years old are at high risk of respiratory infections and nasal irrigation is often prescribed. Yet, to date there is no sufficient knowledge about its immediate effects on the nasopharynx and middle ear. Therefore, this study aimed to analyze the effect of a rhino-pharyngeal clearance intervention protocol on nasal obstruction and middle ear condition in children under 3 years of age with URTI. MATERIALS AND METHODS: Randomized controlled trial in a day-care centre of Porto, including 44 children randomized to Intervention Group (IG) and Control Group (CG)...
June 8, 2018: Acta Otorrinolaringológica Española
https://www.readbyqxmd.com/read/29891143/risk-factors-associated-with-clinical-signs-of-vesicular-stomatitis-and-seroconversion-without-clinical-disease-in-colorado-horses-during-the-2014-outbreak
#9
N J Urie, J E Lombard, K L Marshall, R Digianantonio, A M Pelzel-McCluskey, B J McCluskey, J L Traub-Dargatz, C A Kopral, S L Swenson, J J Schiltz
Vesicular stomatitis (VS) is caused by a contagious rhabdovirus that affects horses, cattle, and swine. Clinical signs of vesicular stomatitis virus (VSV) infection in pigs and cattle are indistinguishable from foot-and-mouth disease (FMD), a foreign animal disease and reportable disease in the United States (Rodriguez et al., 2000). A VS epidemic occurred in the Rocky Mountain region in 2014-15. A study was conducted in Colorado to evaluate horse- and management-level factors associated with VS. For a horse to be considered a clinical VS horse, there were two requirements...
August 1, 2018: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/29891139/validation-of-a-clinical-scoring-system-for-bovine-respiratory-disease-complex-diagnosis-in-preweaned-dairy-calves-using-a-bayesian-framework
#10
S Buczinski, G Fecteau, J Dubuc, D Francoz
Bovine respiratory disease complex is a major cause of illness in dairy calves. The diagnosis of active infection of the lower respiratory tract is challenging on daily basis in the absence of accurate clinical signs. Clinical scoring systems such as the Californian scoring system, are appealing but were developed without considering the imperfection of reference standard tests used for case definition. This study used a Bayesian latent class model to update Californian prediction rules. The results of clinical examination and ultrasound findings of 608 preweaned dairy calves were used...
August 1, 2018: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/29890817/nonshaved-ear-surgery-effect-of-hair-on-surgical-site-infection-of-the-middle-ear-mastoid-surgery-and-patients-preference-for-the-hair-removal
#11
Dong-Hee Lee, Soonil Yoo, Eunhye Shin, Yesun Cho
Background and Objectives: This study aimed 1) to compare the rates of surgical site infection (SSI) between two groups with and without preoperative hair shaving, 2) to compare the bacterial colonization just before the skin incision between them, and 3) to evaluate people's preference for the hair shaving. Subjects and Methods: The retrospective study enrolled cases in which middle ear and mastoid surgery was performed with as well as without hair removal. Main measurement outcomes were the SSI rate within 3 months following the surgery, bacterial culture results obtained from the incision area just before the skin incision, and questionnaire to evaluate the preference for hair shaving from patients with chronic suppurative otitis media but without experience with the ear surgery...
June 14, 2018: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/29884809/in-vivo-detection-of-nanometer-scale-structural-changes-of-the-human-tympanic-membrane-in-otitis-media
#12
Roshan Dsouza, Jungeun Won, Guillermo L Monroy, Malcolm C Hill, Ryan G Porter, Michael A Novak, Stephen A Boppart
Otitis media (OM) is a common ear infection and a leading cause of conductive hearing loss in the pediatric population. Current technologies such as otoscopy, pneumatic otoscopy, tympanometry, and acoustic reflectometry are used to diagnose OM, which can reasonably diagnose the infection with a sensitivity and specificity of 50-90% and 60-90%, respectively. However, these techniques provide limited information about the physical architecture of the tympanic membrane (TM), or what may lie behind it. Here, we report the detection of nanometer-scale structural changes of the TM using nano-sensitive optical coherence tomography (nsOCT)...
June 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29879264/association-of-long-term-risk-of-respiratory-allergic-and-infectious-diseases-with-removal-of-adenoids-and-tonsils-in-childhood
#13
Sean G Byars, Stephen C Stearns, Jacobus J Boomsma
Importance: Surgical removal of adenoids and tonsils to treat obstructed breathing or recurrent middle-ear infections remain common pediatric procedures; however, little is known about their long-term health consequences despite the fact that these lymphatic organs play important roles in the development and function of the immune system. Objective: To estimate long-term disease risks associated with adenoidectomy, tonsillectomy, and adenotonsillectomy in childhood...
June 7, 2018: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29878878/experimental-transmission-of-frog-virus-3-like-ranavirus-in-juvenile-chelonians-at-two-temperatures
#14
Matthew C Allender, Ashley C Barthel, Jeremy M Rayl, Karen A Terio
The pathogenicity of frog virus 3 (FV3)-like ranavirus varies in adult chelonian species at different environmental temperatures, but differences in pathogenicity at different temperatures has yet to be determined in juveniles. Our objective was to determine the susceptibility to FV3-like ranavirus in four species of juvenile chelonians: red-eared sliders (RES; Trachemys scripta elegans), Mississippi map turtles ( Graptemys pseudogeographica kohnii), false map turtles (FMT; Graptemys pseudogeographica), and eastern river cooters ( Pseudemys concinna concinna) at two environmental temperatures...
June 7, 2018: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/29869562/practice-patterns-of-south-african-audiologists-in-cerumen-management-a-pilot-study
#15
Mukovhe Phanguphangu
OBJECTIVE: To determine the training, self-reported competence and practice patterns of South African audiologists (SAAs) regarding cerumen management (CM). DESIGN: Prospective cross-sectional survey. An online questionnaire was completed by SAA between July and September 2016. The questionnaire addressed sections on educational training, experience and practice patterns of SAAs regarding CM. STUDY SAMPLE: Three hundred and fifty-six SAAs responded to an email invitation sent to 382 actively-practicing audiologists...
June 5, 2018: International Journal of Audiology
https://www.readbyqxmd.com/read/29862200/drug-prescription-behavior-a-cross-sectional-study-in-public-health-facilities-in-two-states-of-north-india
#16
Jaya Prasad Tripathy, Pankaj Bahuguna, Shankar Prinja
Background: Poor prescription practices result in increased side effects, adverse drug reactions, and high cost of treatment. The present study was undertaken to describe the drug-prescribing patterns in two North Indian states through prescription auditing. Materials and Methods: The study was carried out in 80 public health facilities across 12 districts in two states of Haryana and Punjab (6 in each) covering all levels of care. The information from prescription slips was abstracted on a structured pro forma for all patients who visited the pharmacy of the health facility...
April 2018: Perspectives in Clinical Research
https://www.readbyqxmd.com/read/29861219/orofacial-pain-of-cervical-origin-a-case-report
#17
G Shankar Ganesh, Mamata Manjari Sahu, Pramod Tigga
BACKGROUND: The etiopathogenesis of orofacial pain remains complex and a number of pain referral patterns for this region have been reported in the literature. The purpose of this report is to describe the assessment and successful clinical management of orofacial pain possibly attributable to cervical origin. CASE DESCRIPTION: A 55-year-old male teacher with a 3-year history of pain in the right lower jaw, radiating to the ear, consulted our institute for assessment and management...
April 2018: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/29859589/radiological-differences-between-hiv-positive-and-hiv-negative-children-with-cholesteatoma
#18
J K McGuire, J J Fagan, M Wojno, K Manning, T Harris
INTRODUCTION: HIV-positive children are possibly more prone to developing cholesteatoma. Chronic inflammation of the middle ear cleft may be more common in patients with HIV and this may predispose HIV-positive children to developing cholesteatoma. There are no studies that describe the radiological morphology of the middle ear cleft in HIV-positive compared to HIV-negative children with cholesteatoma. OBJECTIVES: Compare the radiological differences of the middle ear cleft in HIV-positive and HIV-negative children with cholesteatoma...
July 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29859574/middle-ear-disease-in-danish-toddlers-attending-nursery-day-care-applicability-of-om-6-disease-specific-quality-of-life-and-predictors-for-middle-ear-symptoms
#19
J H Indius, S K Alqaderi, A D Kjeldsen, C H Heidemann
OBJECTIVES: Otitis media (OM) is a very common childhood disease and impacts child quality of life (QoL) to different extends. The aim of this study was to investigate the difference in quality of life between three groups of children; Children with symptoms of ear disease within the last 4 weeks, children without any ear disease and children scheduled for ventilating tube treatment. Furthermore, we investigated predictors for experiencing middle ear symptoms. Lastly, we assessed psychometric properties of OM-6 used to assess QoL...
July 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29852129/leishmaniasis-caused-by-leishmania-viannia-guyanensis-in-north-central-pacific-region-of-ecuador-a-clinico-epidemiological-feature
#20
Eduardo A Gomez, Hirotomo Kato, Edison X Torres-Romero, Lenin N Velez, Nancy V Villegas, Virginia P Martillo, Flavio C Zambrano, Makoto Kubo, Kazue Hashiguchi, Yoshihisa Hashiguchi
The current four year study was undertaken to investigate the clinical and epidemiological features of Leishmania (Viannia) guyanensis infections in Valle Hermoso, Santo Domingo de Los Tsachilas province, north-central Pacific areas of Ecuador. A total of 155 parasitologically confirmed (Leishmania-amastigote-positive) clinical cases diagnosed at a rural health center during January 2014-December 2017 were analyzed thoroughly. Molecular characterization of the causative Leishmania parasites from different endemic sites within the study areas was performed by PCR amplification of cytochrome b (cyt b) sequencing...
May 28, 2018: Acta Tropica
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