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https://www.readbyqxmd.com/read/28636064/side-scattered-finger-photoplethysmography-experimental-investigations-toward-practical-noninvasive-measurement-of-blood-glucose
#1
Yasuhiro Yamakoshi, Kenta Matsumura, Takehiro Yamakoshi, Jihyoung Lee, Peter Rolfe, Yuji Kato, Koichi Shimizu, Ken-Ichi Yamakoshi
No abstract text is available yet for this article.
June 1, 2017: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/28635611/modulatory-effects-of-naringin-on-hepatic-key-enzymes-of-carbohydrate-metabolism-in-high-fat-diet-low-dose-streptozotocin-induced-diabetes-in-rats
#2
Leelavinothan Pari, Ramasamy Chandramohan
We evaluated the modulatory effects of naringin on altered hepatic key enzymes of carbohydrate metabolism in high-fat diet/low-dose streptozotocin-induced diabetic rats. Oral treatment of naringin at a doses of 20, 40 and 80 mg/kg body weight to diabetic rats for 30 days resulted in a significant reduction in the levels of plasma glucose, blood glycosylated hemoglobin and increase in the levels of plasma insulin and blood hemoglobin. The altered activities of the hepatic key enzymes of carbohydrate metabolism such as hexokinase, glucose-6-phosphatase, fructose-1,6-bisphosphatase, glucose-6-phosphate dehydrogenase, glycogen synthase, glycogen phosphorylase and glycogen content of diabetic rats were significantly reverted to near normal levels by the treatment of naringin in a dose-dependent manner...
July 2017: General Physiology and Biophysics
https://www.readbyqxmd.com/read/28634625/serum-antioxidant-capacity-biochemical-profile-and-body-composition-of-breast-cancer-survivors-in-a-randomized-mediterranean-dietary-intervention-study
#3
Maria Skouroliakou, D Grosomanidis, P Massara, C Kostara, P Papandreou, D Ntountaniotis, G Xepapadakis
PURPOSE: Increasing evidence suggests that Mediterranean Diet (MD) is correlated with reduced risk of breast cancer (BC) and cancer mortality, since it modifies patients' serum antioxidant capacity, body composition and biochemical parameters. The aim of the study was to investigate whether a dietary intervention based on MD has a beneficial effect on these factors. METHODS: In this intervention study, seventy female BC survivors were randomly assigned to (1) the intervention group (personalized dietary intervention based on MD) and (2) the control group (received the updated American Cancer Society Guidelines on Nutrition and Physical Activity for Cancer Prevention and ad libitum diet)...
June 20, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28634587/exercise-metabolism-in-nonobese-patients-with-type-2-diabetes-following-the-acute-restoration-of-normoglycaemia
#4
Christopher J Gaffney, Peter Mansell, Francis B Stephens, Ian A Macdonald, Kostas Tsintzas
This study investigated how acute restoration of normoglycaemia affected energy metabolism during exercise in nonobese patients with type 2 diabetes. Six subjects (mean ± SEM) aged 56.2 ± 2.7 years, with a BMI of 24.5 ± 1.5 kg/m(2) and a VO2 peak of 28.7 ml/kg/min, attended the lab on two randomised occasions for a four-hour resting infusion of insulin or saline, followed by 30 minutes cycling at 50% VO2 peak. During the 4 h resting infusion, there was a greater (P < 0.0001) reduction in blood glucose in insulin treatment (INS) (from 11...
2017: Journal of Diabetes Research
https://www.readbyqxmd.com/read/28634381/impact-of-initial-active-engagement-in-self-monitoring-with-a-telemonitoring-device-on-glycemic-control-among-patients-with-type-2-diabetes
#5
Min-Kyung Lee, Kwang-Hyeon Lee, Seung-Hyun Yoo, Cheol-Young Park
This study aimed to investigate the effect of patient engagement in self-monitoring with a telemonitoring device on glycemic control among patients with type 2 diabetes. We conducted a subanalysis of the telemonitoring device study in Kaiser Permanente Northern California members. We divided the telemonitoring group into 53 frequent and 54 infrequent users based on self-monitoring of blood glucose (SMBG) frequency of the first 6 weeks. The frequency of SMBG transmitted from the telemonitoring device was examined over 24 weeks...
June 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28633769/blisters-in-ankle-fractures-a-retrospective-cohort-study
#6
David González Quevedo, Juan Manuel Sánchez Siles, Facundo Rojas Tomba, Iskandar Tamimi Mariño, Manuel Francisco Bravo Bardaji, Francisco Villanueva Pareja
The most frequent postoperative complications after an ankle fracture are usually skin related. We present the results of a retrospective study of 112 patients with ankle fracture who had undergone open reduction and internal fixation from January 2014 to December 2014. The following features were analyzed: patient comorbidities, fracture type, the presence of an open fracture or fracture-dislocation, timing and duration of surgery, preoperative glucose level, and short-term complications (i.e., blisters, wound dehiscence, deep and superficial infections, and reintervention)...
July 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28633537/extensive-assessment-of-blood-glucose-monitoring-during-postprandial-period-and-its-impact-on-closed-loop-performance
#7
Lyvia Biagi, Arthur Hirata Bertachi, Ignacio Conget, Carmen Quirós, Marga Giménez, F Javier Ampudia-Blasco, Paolo Rossetti, Jorge Bondia, Josep Vehí
BACKGROUND: Closed-loop (CL) systems aims to outperform usual treatments in blood glucose control and continuous glucose monitors (CGM) are a key component in such systems. Meals represents one of the main disturbances in blood glucose control, and postprandial period (PP) is a challenging situation for both CL system and CGM accuracy. METHODS: We performed an extensive analysis of sensor's performance by numerical accuracy and precision during PP, as well as its influence in blood glucose control under CL therapy...
June 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/28633442/continuous-glucose-monitoring-in-female-nod-mice-reveals-daily-rhythms-and-a-negative-correlation-with-body-temperature
#8
Ron Korstanje, Jennifer L Ryan, Holly S Savage, Bonnie L Lyons, Kevin G Kane, Stacey J Sukoff Rizzo
Previous studies with continuous glucose monitoring in mice have been limited to several days or weeks, with the mouse's physical attachment to the equipment impacting behavior and measurements. In the current study we measured blood glucose and body temperature at 10-second intervals for 12 weeks in a cohort of NOD/ShiLtJ female mice using wireless telemetry. This allowed us, for the first time, to obtain a high-resolution profile of the circadian rhythm of these two parameters and the onset of hyperglycemic development in real time...
June 19, 2017: Endocrinology
https://www.readbyqxmd.com/read/28633303/cognitive-trajectories-in-prediabetes-and-diabetes-a-population-based-cohort-study
#9
Anna Marseglia, Anna K Dahl Aslan, Laura Fratiglioni, Giola Santoni, Nancy L Pedersen, Weili Xu
Background: Diabetes has been linked to dementia risk; however, the cognitive trajectories in older adults with diabetes remain unclear. We aimed to investigate the effect of prediabetes and diabetes on cognitive trajectories among cognitively intact older adults in a long-term follow-up study. Methods: Within the Swedish Adoption/Twin Study of Aging, 793 cognitively intact older adults aged ≥50 were identified at baseline and followed for up to 23 years. Based on standardized scores from 11 cognitive tests, administered at baseline and up to seven follow-ups, four cognitive domains (verbal abilities, spatial/fluid, memory, perceptual speed) were identified by principal-component analysis...
June 13, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28633297/sauna-bathing-and-incident-hypertension-a-prospective-cohort-study
#10
Francesco Zaccardi, Tanjaniina Laukkanen, Peter Willeit, Setor K Kunutsor, Jussi Kauhanen, Jari A Laukkanen
BACKGROUND: Sauna bathing is associated with reduced cardiovascular risk, but the mechanisms underlying this beneficial effect are not entirely understood. We aimed to assess the relationship between sauna bathing and risk of incident hypertension. METHODS: Frequency of sauna bathing was ascertained using questionnaires in the Kuopio Ischemic Heart Disease Study, a prospective cohort study conducted in Eastern Finland that comprised a population-based sample of 1,621 men aged 42 to 60 years without hypertension at baseline...
June 13, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28632918/predicting-inpatient-hypoglycaemia-in-hospitalized-patients-with-diabetes-a-retrospective-analysis-of-9584-admissions-with-diabetes
#11
K Stuart, N J Adderley, T Marshall, G Rayman, A Sitch, S Manley, S Ghosh, K A Toulis, K Nirantharakumar
AIMS: To explore whether a quantitative approach to identifying hospitalized patients with diabetes at risk of hypoglycaemia would be feasible through incorporation of routine biochemical, haematological and prescription data. METHODS: A retrospective cross-sectional analysis of all diabetic admissions (n=9584) from 1 January 2014 to 31 December 2014 was performed. Hypoglycaemia was defined as a blood glucose level of <4 mmol/l. The prediction model was constructed using multivariable logistic regression, populated by clinically important variables and routine laboratory data...
June 20, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28632873/screening-for-obesity-and-intervention-for-weight-management-in-children-and-adolescents-evidence-report-and-systematic-review-for-the-us-preventive-services-task-force
#12
Elizabeth A O'Connor, Corinne V Evans, Brittany U Burda, Emily S Walsh, Michelle Eder, Paula Lozano
Importance: Obesity is common in children and adolescents in the United States, is associated with negative health effects, and increases the likelihood of obesity in adulthood. Objective: To systematically review the benefits and harms of screening and treatment for obesity and overweight in children and adolescents to inform the US Preventive Services Task Force. Data Sources: MEDLINE, PubMed, PsycINFO, Cochrane Collaboration Registry of Controlled Trials, and the Education Resources Information Center through January 22, 2016; references of relevant publications; government websites...
June 20, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28632494/long-term-dutasteride-therapy-in-men-with-benign-prostatic-hyperplasia-alters-glucose-and-lipid-profiles-and-increases-severity-of-erectile-dysfunction
#13
Abdulmaged Traish, Karim Sultan Haider, Gheorghe Doros, Ahmad Haider
Background Dutasteride has been successfully used in treatment of lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH). However, dutasteride inhibits 5α-reductase type 1 and type 2 enzymes and may compromises glucocorticoids and androgen metabolism and alters metabolic function resulting in undesirable metabolic and sexual adverse side effects. Aim The aim of this study was to investigate the long-term adverse effects of dutasteride therapy in men with BPH on: i) blood glucose, ii) glycated hemoglobin (HbA1c), iii) low density lipoprotein-cholesterol (LDL-C); high density lipoprotein-cholesterol (HDL-C) and total cholesterol (TC), iv) testosterone (T), v) liver alanine and aspartate aminotransferases (ALT and AST) and vi) erectile dysfunction (ED)...
June 21, 2017: Hormone Molecular Biology and Clinical Investigation
https://www.readbyqxmd.com/read/28632483/cardiovascular-disease-risk-profile-of-ncaa-division-iii-intercollegiate-football-athletes-a-pilot-study
#14
Cynthia J Wright, Elizabeth L Abbey, Barbara A Brandon, Edward J Reisman, Christina M Kirkpatrick
OBJECTIVES: Concerns about the long-term cardiovascular health implications of American football participation have been investigated at the professional and Division I levels, but limited research is available at the less resourced Division III level. Therefore, the objective was to assess the cardiovascular disease risk profile of NCAA Division III intercollegiate football athletes. METHODS: Eighty-nine varsity football athletes (age=19.6±1.7 years, height=1...
June 20, 2017: Physician and Sportsmedicine
https://www.readbyqxmd.com/read/28632422/risk-of-diabetes-and-dyslipidemia-during-clozapine-and-other-antipsychotic-drug-treatment-of-schizophrenia-in-iceland
#15
Oddur Ingimarsson, James H MacCabe, Magnús Haraldsson, Halldóra Jónsdóttir, Engilbert Sigurdsson
BACKGROUND: Type 2 diabetes (T2D) and raised blood lipids are associated with the use of antipsychotics, not least clozapine. AIMS: To describe the prevalence of high blood glucose levels, T2D, and dyslipidemia, in association with the use of clozapine or other antipsychotics in patients with schizophrenia in Iceland. METHOD: This study identified 188 patients treated with clozapine and 395 patients never treated with clozapine by searching the electronic health records of Landspitali, the National University Hospital...
June 20, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28631582/effect-of-green-tea-extract-supplementation-on-glycogen-replenishment-in-exercised-human-skeletal-muscle
#16
Tsen-Wei Tsai, Chia-Chen Chang, Su-Fen Liao, Yi-Hung Liao, Chien-Wen Hou, Jung-Piao Tsao, I-Shiung Cheng
The purpose of this study was to investigate the effects of 8-week green tea extract (GTE) supplementation on promoting postexercise muscle glycogen resynthesis and systemic energy substrate utilisation in young college students. A total of eight healthy male participants (age: 22·0 (se 1·0) years, BMI: 24·2 (se 0·7) kg/m2, VO2max: 43·2 (se 2·4) ml/kg per min) participated in this study. GTE (500 mg/d for 8 weeks) was compared with placebo in participants in a double-blind/placebo-controlled and crossover study design with an 8-week washout period...
June 20, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28631393/comparison-of-thiazide-like-diuretics-versus-thiazide-type-diuretics-a-meta-analysis
#17
REVIEW
Wenjing Liang, Hui Ma, Luxi Cao, Wenjiang Yan, Jingjing Yang
Thiazide diuretics are widely used for the management of hypertension. In recent years, it has been actively debated that there is interchangeability of thiazide-type diuretics hydrochlorothiazide and thiazide-like diuretics including indapamide and chlorthalidone for the treatment of hypertension. With the purpose of seeking out the best thiazide diuretic for clinicians, we summarized the existing evidence on the two types of drugs and conducted a meta-analysis on their efficacy in lowering blood pressure and effects on blood electrolyte, glucose and total cholesterol...
June 19, 2017: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/28631330/foxo-transcription-factors-at-the-interface-of-metabolism-and-cancer
#18
REVIEW
Wolfgang Link, Pablo J Fernandez-Marcos
Diabetes refers to a group of metabolic diseases characterized by impaired insulin signalling and high blood glucose. A growing body of epidemiological evidence links diabetes to several types of cancer but the underlying molecular mechanisms are poorly understood. The signalling cascade connecting insulin and FOXO proteins provides a compelling example for a conserved pathway at the interface between insulin signalling and cancer. FOXOs are transcription factors that orchestrate programs of gene expression known to control a variety of processes in response to cellular stress...
June 19, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28631010/the-metabolic-cost-of-nesting-body-condition-and-blood-parameters-of-caiman-crocodilus-and-melanosuchus-niger-in-central-amazonia
#19
José António Lemos Barão-Nóbrega, Boris Marioni, Robinson Botero-Arias, António José Arsénia Nogueira, Emerson Silva Lima, William Ernest Magnusson, Ronis Da Silveira, Jaydione Luiz Marcon
Although nesting ecology is well studied in several crocodilian species, it is not known how nest attendance influences physiology and body condition of nesting females. In this study, we describe body condition and serum biochemical values of nesting female, non-nesting female and male spectacled caiman (Caiman crocodilus) and black caiman (Melanosuchus niger) in two areas of Central Amazonia. We also evaluated the effect of nest age and nest distance to water on body condition and blood parameters of nesting females...
June 19, 2017: Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology
https://www.readbyqxmd.com/read/28630631/urinalysis-and-clinical-correlations-in-patients-with-p-vivax-or-p-falciparum-malaria-from-colombia
#20
Alberto Tobón-Castaño, Sebastián Barrera Escobar, Cecilia Giraldo Castro
BACKGROUND: Urinalysis is a poorly reviewed diagnostic tool in malaria patients; its application can show the presence of severe malaria. METHODS: Urinalysis was performed in a total of 620 patients diagnosed with malaria by thick blood smear; complications were classified according to WHO major criteria for severity and minor criteria according to the Colombian malaria guideline. RESULTS: Severe or moderate clinical complications were diagnosed in 31...
2017: Journal of Tropical Medicine
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