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https://www.readbyqxmd.com/read/28810399/identification-and-regulation-of-emotions-in-adults-of-varying-weight-statuses
#1
Andrea E Kass, Jennifer E Wildes, Emil F Coccaro
Comparing individuals of varying weight statuses on their identification and regulation of emotions may increase our understanding of mechanisms that drive excess weight gain and highlight more precise weight regulation targets. In Study I ( N = 1333), adults with obesity had reduced self-reported attention to and repair of emotions compared to adults with overweight or normal weight. In Study II ( N = 85), adults with obesity had deficits in assessor-administrated tasks of strategic emotional intelligence (i...
February 1, 2017: Journal of Health Psychology
https://www.readbyqxmd.com/read/28808824/gasless-single-incision-laparoscopic-inguinal-hernia-repair-initial-experience
#2
M W V Ng, K C Ng
PURPOSE: Laparoscopic hernioplasty has been gaining its popularity in the past decade for its rapid recovery. Single-incision surgery, as its possible advancement, has also received more attention. Traditional laparoscopic surgery with carbon dioxide insufflation precluded patients with underlying cardiovascular or pulmonary disease from minimal invasive surgery. We report our early experience with gasless single-incision laparoscopic inguinal hernia repair via totally extraperitoneal (TEP) approach...
August 14, 2017: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/28805207/periodontal-diseases
#3
REVIEW
Denis F Kinane, Panagiota G Stathopoulou, Panos N Papapanou
Periodontal diseases comprise a wide range of inflammatory conditions that affect the supporting structures of the teeth (the gingiva, bone and periodontal ligament), which could lead to tooth loss and contribute to systemic inflammation. Chronic periodontitis predominantly affects adults, but aggressive periodontitis may occasionally occur in children. Periodontal disease initiation and propagation is through a dysbiosis of the commensal oral microbiota (dental plaque), which then interacts with the immune defences of the host, leading to inflammation and disease...
June 22, 2017: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/28804813/a-systematic-review-of-the-clinical-applications-and-complications-of-bone-marrow-aspirate-concentrate-in-management-of-bone-defects-and-nonunions
#4
REVIEW
Mohamed A Imam, James Holton, Lukas Ernstbrunner, Wojciech Pepke, Florian Grubhofer, Ali Narvani, Martyn Snow
PURPOSE: Fracture healing encompasses a succession of dynamic multifactorial metabolic events, which ultimately re-establishes the integrity of the biomechanical properties of the bone. Up to 10% of the fractures occurring annually will need additional surgical procedures because of impaired healing. The aim of this article is to review the current literature regarding the use of bone marrow aspirate concentrate (BMAC) and its effectiveness in the management of bone defects. METHODS: We have included all published clinical literature investigating the development, techniques and applications of BMAC...
August 13, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28799471/pathways-between-combat-stress-and-physical-health-among-portuguese-war-veterans
#5
Paulo Correia Ferrajão
In this study, I explored the experience of both physical and psychological chronic illnesses among a sample of Portuguese war veterans. Twenty suffered from chronic posttraumatic stress disorder (PTSD; unrecovered) and 20 had remission from PTSD (recovered), and all participants suffered from a chronic physician-diagnosed medical disorder. Two semistructured interviews were conducted. Analysis of the interviews was conducted using the Thematic and Categorical Analysis. Unrecovered participants reported higher moral injury, discrepancy between pre- and postwar identity, medication side effects, and lower repertoire of coping strategies, and verbalized that treatment care plan triggers posttraumatic symptoms...
September 2017: Qualitative Health Research
https://www.readbyqxmd.com/read/28794879/human-papillomavirus-driven-immune-deviation-challenge-and-novel-opportunity-for-immunotherapy
#6
REVIEW
Sigrun Smola, Connie Trimble, Peter L Stern
It is now recognized that the immune system can be a key component of restraint and control during the neoplastic process. Human papillomavirus (HPV)-associated cancers of the anogenital tract and oropharynx represent a significant clinical problem but there is a clear opportunity for immune targeting of the viral oncogene expression that drives cancer development. However, high-risk HPV infection of the target epithelium and the expression of the E6/E7 oncogenes can lead to early compromise of the innate immune system (loss of antigen-presenting cells) facilitating viral persistence and increased risk of cancer...
June 2017: Therapeutic Advances in Vaccines
https://www.readbyqxmd.com/read/28794219/dodging-silver-bullets-good-crispr-gene-drive-design-is-critical-for-eradicating-exotic-vertebrates
#7
Thomas A A Prowse, Phillip Cassey, Joshua V Ross, Chandran Pfitzner, Talia A Wittmann, Paul Thomas
Self-replicating gene drives that can spread deleterious alleles through animal populations have been promoted as a much needed but controversial 'silver bullet' for controlling invasive alien species. Homing-based drives comprise an endonuclease and a guide RNA (gRNA) that are replicated during meiosis via homologous recombination. However, their efficacy for controlling wild populations is threatened by inherent polymorphic resistance and the creation of resistance alleles via non-homologous end-joining (NHEJ)-mediated DNA repair...
August 16, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/28782236/porous-titanium-scaffolds-with-self-assembled-micro-nano-hierarchical-structure-for-dual-functions-of-bone-regeneration-and-anti-infection
#8
Lu Han, Menghao Wang, Honglong Sun, Peifei Li, Kefeng Wang, Fuzeng Ren, Xiong Lu
Porous titanium (Ti) scaffolds are widely used for bone repair because of their good biocompatibility, mechanical properties and corrosion resistance. However, pristine Ti scaffolds are bioinert and unable to induce bone regeneration. In this study, chitosan coated BSA nanoparticles (CBSA NPs) and oxidized alginate (OSA) were in a layer-by-layer (LbL) manner on Ti scaffolds. The LbL film possessed micro/nano hierarchical architectures, has the features of nanostructures, and possesses abundant functional groups from CBSA NPs and OSA to improve the surface biocompatibility and biofunctionality of Ti scaffolds...
August 7, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28777437/double-sex-and-mab-3-related-transcription-factor-1-regulates-differentiation-and-proliferation-in-dairy-goat-male-germline-stem-cells
#9
Yudong Wei, Shufang Cai, Fanglin Ma, Ying Zhang, Zhe Zhou, Shuanshuan Xu, Mengfei Zhang, Sha Peng, Jinlian Hua
The protein encoded by double sex and mab-3 related transcription factor 1 (Dmrt1)gene contains a double sex/mab-3 domain, which was considered as one of the most conservative structures in sex determination. However, its effect on spermatogenesis of dairy goat spermatogonial stem cells (SSCs) remains to be clarified. For the first time, the roles of Dmrt1 in spermatogenesis of livestock are highlighted. Here, we investigated the expression pattern of Dmrt1 in the testes of dairy goats. Dmrt1 primarily located in undifferentiated SSCs...
August 4, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/28777374/high-mobility-group-a1-protein-modulates-autophagy-in-cancer-cells
#10
Andrea Conte, Simona Paladino, Gaia Bianco, Dominga Fasano, Raffaele Gerlini, Mara Tornincasa, Maurizio Renna, Alfredo Fusco, Donatella Tramontano, Giovanna Maria Pierantoni
High Mobility Group A1 (HMGA1) is an architectural chromatin protein whose overexpression is a feature of malignant neoplasias with a causal role in cancer initiation and progression. HMGA1 promotes tumor growth by several mechanisms, including increase of cell proliferation and survival, impairment of DNA repair and induction of chromosome instability. Autophagy is a self-degradative process that, by providing energy sources and removing damaged organelles and misfolded proteins, allows cell survival under stress conditions...
August 4, 2017: Cell Death and Differentiation
https://www.readbyqxmd.com/read/28774526/gopro-hero-4-black-recording-of-scleral-buckle-placement-during-retinal-detachment-repair
#11
Vincent Y Ho, Vaishali G Shah, David M Yates, Gaurav K Shah
OBJECTIVE: GoPro and Google Glass technology have previously been used to record procedures in ophthalmology and other medical fields. In this manuscript, GoPro's latest HERO 4 Black edition camera (GoPro Inc, San Mateo, Calif.) will be used to record the placement of a scleral buckle during retinal detachment surgery. METHODS: GoPro HERO 4 Black edition camera, which records 4K-quality video with a resolution of 3840 (pixels) x 2160 (lines), was mounted on a head strap to record placement of a scleral buckle for a retinal detachment...
August 2017: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/28772498/3d-printing-of-cytocompatible-water-based-light-cured-polyurethane-with-hyaluronic-acid-for-cartilage-tissue-engineering-applications
#12
Ming-You Shie, Wen-Ching Chang, Li-Ju Wei, Yu-Hsin Huang, Chien-Han Chen, Cheng-Ting Shih, Yi-Wen Chen, Yu-Fang Shen
Diseases in articular cartilages have affected millions of people globally. Although the biochemical and cellular composition of articular cartilages is relatively simple, there is a limitation in the self-repair ability of the cartilage. Therefore, developing strategies for cartilage repair is very important. Here, we report on a new liquid resin preparation process of water-based polyurethane based photosensitive materials with hyaluronic acid with application of the materials for 3D printed customized cartilage scaffolds...
February 8, 2017: Materials
https://www.readbyqxmd.com/read/28772409/a-novel-design-of-autonomously-healed-concrete-towards-a-vascular-healing-network
#13
Pieter Minnebo, Glenn Thierens, Glenn De Valck, Kim Van Tittelboom, Nele De Belie, Danny Van Hemelrijck, Eleni Tsangouri
Concrete is prone to crack formation in the tensile zone, which is why steel reinforcement is introduced in these zones. However, small cracks could still arise, which give liquids and gasses access to the reinforcement causing it to corrode. Self-healing concrete repairs and seals these small (300 µm) cracks, preventing the development of corrosion. In this study, a vascular system, carrying the healing agent, is developed. It consists of tubes connected to a 3D printed distribution piece. This distribution piece has four outlets that are connected to the tubes and has one inlet, which is accessible from outside...
January 8, 2017: Materials
https://www.readbyqxmd.com/read/28772363/quantification-of-the-service-life-extension-and-environmental-benefit-of-chloride-exposed-self-healing-concrete
#14
Bjorn Van Belleghem, Philip Van den Heede, Kim Van Tittelboom, Nele De Belie
Formation of cracks impairs the durability of concrete elements. Corrosion inducing substances, such as chlorides, can enter the matrix through these cracks and cause steel reinforcement corrosion and concrete degradation. Self-repair of concrete cracks is an innovative technique which has been studied extensively during the past decade and which may help to increase the sustainability of concrete. However, the experiments conducted until now did not allow for an assessment of the service life extension possible with self-healing concrete in comparison with traditional (cracked) concrete...
December 23, 2016: Materials
https://www.readbyqxmd.com/read/28772269/effects-of-self-assembling-peptide-p11-4-fluorides-and-caries-infiltration-on-artificial-enamel-caries-lesions-in-vitro
#15
Richard J Wierichs, Julian Kogel, Julian Lausch, Marcella Esteves-Oliveira, Hendrik Meyer-Lueckel
The application of a self-assembling peptide on noncavitated caries lesions is supposed to be a feasible approach to facilitate remineralization and mask their unfavorable appearance. However, demineralizing conditions are common in the oral environment, so the aim of this pH-cycling study was to compare recommended and novel treatment methods regarding their ability to hamper demineralization and as a consequence mask artificial enamel caries lesions. Artificial caries lesions were prepared in bovine enamel and randomly allocated to 11 groups (n = 22)...
August 4, 2017: Caries Research
https://www.readbyqxmd.com/read/28771375/recent-development-and-biomedical-applications-of-self-healing-hydrogels
#16
Yinan Wang, Christian K Adokoh, Ravin Narain
Hydrogels are of special importance, owing to their high-water content and various applications in biomedical and bio-engineering research. Self-healing properties is a common phenomenon in living organisms. Their endowed property of being able to self-repair after physical/chemical/mechanical damage to fully or partially its original properties demonstrates their prospective therapeutic applications. Due to complicated preparation and selection of suitable materials, the application of many host-guest supramolecular polymeric hydrogels are so limited...
August 3, 2017: Expert Opinion on Drug Delivery
https://www.readbyqxmd.com/read/28771328/directing-stem-cell-fate-the-synthetic-natural-product-connection
#17
Trevor C Johnson, Dionicio Siegel
Stem cells possess remarkable potential for the treatment of a broad array of diseases including many that lack therapeutic options. However, the use of cell-based products derived from stem cells as therapeutics has limitations including rejection, sufficient availability, and lack of appropriate engraftment. Chemical control of stem cells provides potential solutions for overcoming many of the current limitations in cell-based therapeutics. The development of exogenous molecules to control stem cell self-renewal or differentiation has arrived at natural product-based agents as an important class of modulators...
August 3, 2017: Chemical Reviews
https://www.readbyqxmd.com/read/28769041/self-healing-of-damage-inside-metals-triggered-by-electropulsing-stimuli
#18
Hui Song, Zhong-Jin Wang, Xiao-Dong He, Jie Duan
The microscopic defects that distributed randomly in metals are not only hard to detect, but also may inevitably cause catastrophic failure. Thus, autonomic probing and healing for damage inside metals continue to be a challenging. Here we show a novel approach for self-healing using electropulsing as a stimulus to trigger repairing of damaged metals. This is achieved via a process that through expelling absolutely currents, the microcrack causes them to be redistributed to form a concentrated and a diluted region around it, thereby inducing an extremely high temperature gradient and a large compressive stress, which drive material flow to close microcracks...
August 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28767798/conventional-inguinal-hernia-repair-with-self-fixating-mesh-versus-totally-extraperitoneal-laparoscopic-repair-with-polypropylene-mesh-early-postoperative-results
#19
José Antonio Cunha-E-Silva, Flávio Malcher Martins de Oliveira, Antonio Felipe Santa Maria Coquillard Ayres, Antonio Carlos Ribeiro Garrido Iglesias
Objective: to evaluate the early postoperative results of inguinal hernia repair by the conventional technique with self-fixating mesh versus laparoscopic totally extraperitoneal repair with polypropylene mesh. We compared pain, surgical time and early complications. Methods: this is a prospective, case-series study of 80 consecutive patients treated in the surgical clinic of the Gaffrée e Guinle University Hospital (HUGG). We included patients with unilateral inguinal hernia, not relapsed and operated only on an elective basis...
May 2017: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/28766839/techniques-and-outcomes-of-paravalvular-leak-repair-after-transcatheter-aortic-valve-replacement
#20
Thomas M Waterbury, Guy S Reeder, Sorin V Pislaru, Allison K Cabalka, Charanjit S Rihal, Mackram F Eleid
OBJECTIVES: To investigate the feasibility, procedural success, and outcomes of paravalvular leak (PVL) closure in patients with prior transcatheter aortic valve replacement (TAVR). BACKGROUND: PVL after TAVR is associated with adverse patient outcomes and increased mortality. Percutaneous PVL closure has emerged as a therapeutic strategy for addressing this issue, but data for transcatheter PVL repair after TAVR remains limited. METHODS: This is a single center retrospective review of PVL closure after TAVR...
August 2, 2017: Catheterization and Cardiovascular Interventions
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