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https://www.readbyqxmd.com/read/28319479/brainstem-evoked-potential-indices-of-subcortical-auditory-processing-after-mild-traumatic-brain-injury
#1
Kathy R Vander Werff, Brian Rieger
OBJECTIVES: The primary aim of this study was to assess subcortical auditory processing in individuals with chronic symptoms after mild traumatic brain injury (mTBI) by measuring auditory brainstem responses (ABRs) to standard click and complex speech stimuli. Consistent with reports in the literature of auditory problems after mTBI (despite normal-hearing thresholds), it was hypothesized that individuals with mTBI would have evidence of impaired neural encoding in the auditory brainstem compared to noninjured controls, as evidenced by delayed latencies and reduced amplitudes of ABR components...
March 17, 2017: Ear and Hearing
https://www.readbyqxmd.com/read/28318934/performance-evaluation-of-the-pilot-scale-upflow-anaerobic-sludge-blanket-downflow-hanging-sponge-system-for-natural-rubber-processing-wastewater-treatment-in-south-vietnam
#2
Takahiro Watari, Trung Cuong Mai, Daisuke Tanikawa, Yuga Hirakata, Masashi Hatamoto, Kazuaki Syutsubo, Masao Fukuda, Ngoc Bich Nguyen, Takashi Yamaguchi
A pilot-scale upflow anaerobic sludge blanket (UASB)-downflow hanging sponge system (DHS) combined with an anaerobic baffled reactor (ABR) and a settling tank (ST) was installed in a natural rubber processing factory in South Vietnam and its process performance was evaluated for 267days. The UASB reactor achieved a total removal efficiency of 55.6±16.6% for chemical oxygen demand (COD) and 77.8±10.3% for biochemical oxygen demand (BOD) with an organic loading rate of 1.7±0.6kg-COD·m(-3)·day(-1). The final effluent of the proposed system had 140±64mg·L(-1) of total COD, 31±12mg·L(-1) of total BOD, and 58±24mg-N·L(-1) of total nitrogen...
March 7, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28297451/radshield-semiautomated-shielding-design-using-a-floor-plan-driven-graphical-user-interface
#3
Matthew C DeLorenzo, Dee H Wu, Kai Yang, Isaac B Rutel
The purpose of this study was to introduce and describe the development of RadShield, a Java-based graphical user interface (GUI), which provides a base design that uniquely performs thorough, spatially distributed calculations at many points and reports the maximum air-kerma rate and barrier thickness for each barrier pursuant to NCRP Report 147 methodology. Semiautomated shielding design calculations are validated by two approaches: a geometry-based approach and a manual approach. A series of geometry-based equations were derived giving the maximum air-kerma rate magnitude and location through a first derivative root finding approach...
September 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28293251/an-active-mitochondrial-complex-ii-present-in-mature-seeds-contains-an-embryo-specific-iron-sulfur-subunit-regulated-by-aba-and-bzip53-and-is-involved-in-germination-and-seedling-establishment
#4
Franko Restovic, Roberto Espinoza-Corral, Isabel Gómez, Jesús Vicente-Carbajosa, Xavier Jordana
Complex II (succinate dehydrogenase) is an essential mitochondrial enzyme involved in both the tricarboxylic acid cycle and the respiratory chain. In Arabidopsis thaliana, its iron-sulfur subunit (SDH2) is encoded by three genes, one of them (SDH2.3) being specifically expressed during seed maturation in the embryo. Here we show that seed SDH2.3 expression is regulated by abscisic acid (ABA) and we define the promoter region (-114 to +49) possessing all the cis-elements necessary and sufficient for high expression in seeds...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28287619/effects-of-cdh23-single-nucleotide-substitutions-on-age-related-hearing-loss-in-c57bl-6-and-129s1-sv-mice-and-comparisons-with-congenic-strains
#5
Kenneth R Johnson, Cong Tian, Leona H Gagnon, Haiyan Jiang, Dalian Ding, Richard Salvi
A single nucleotide variant (SNV) of the cadherin 23 gene (Cdh23(c.753A)), common to many inbred mouse strains, accelerates age-related hearing loss (AHL) and can worsen auditory phenotypes of other mutations. We used homologous recombination in C57BL/6 NJ (B6N) and 129S1/SvImJ (129S1) embryonic stem cells to engineer mouse strains with reciprocal single base pair substitutions (B6-Cdh23(c.753A>G) and 129S1-Cdh23(c.753G>A)). We compared ABR thresholds and cochlear pathologies of these SNV mice with those of congenic (B6...
March 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28286636/a-comparison-of-commercially-available-auditory-brainstem-response-stimuli-at-a-neurodiagnostic-intensity-level
#6
Devan A Keesling, Jordan Paige Parker, Jason Tait Sanchez
iChirp-evoked auditory brainstem responses (ABRs) yield a larger wave V amplitude at low intensity levels than traditional broadband click stimuli, providing a reliable estimation of hearing sensitivity. However, advantages of iChirp stimulation at high intensity levels are unknown. We tested to see if high-intensity (i.e., 85 dBnHL) iChirp stimulation results in larger and more reliable ABR waveforms than click. Using the commercially available Intelligent Hearing System SmartEP platform, we recorded ABRs from 43 normal hearing young adults...
February 1, 2017: Audiology Research
https://www.readbyqxmd.com/read/28286511/bhbzip60-from-resurrection-plant-boea-hygrometrica-is-an-mrna-splicing-activated-endoplasmic-reticulum-stress-regulator-involved-in-drought-tolerance
#7
Bo Wang, Hong Du, Zhennan Zhang, Wenzhong Xu, Xin Deng
Adverse environmental conditions cause endoplasmic reticulum (ER) stress in plants. To mitigate ER stress damage, ER associated transcription factors and inositol-requiring enzyme-1 (IRE1)-mediated bZIP60 mRNA splicing are activated in plants. A drought-induced gene, encoding the ortholog of AtbZIP60, was identified in the resurrection plant Boea hygrometrica, termed BhbZIP60. In response to ER stress and dehydration, BhbZIP60 mRNA can be spliced to create a frame shift in the C terminus by the excision of 23b segment in a manner of its ortholog in other plants, thus translocating to the nucleus instead of the cytoplasm...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28286366/relations-among-auditory-brainstem-and-middle-latency-response-measures-categorical-loudness-judgments-and-their-associated-physical-intensities
#8
REVIEW
Peggy A Korczak, LaGuinn P Sherlock, Monica L Hawley, Craig Formby
This study characterizes changes in response properties of toneburst-evoked auditory brainstem responses (ABRs) and/or middle latency responses (MLRs) as a function of perceived loudness and physical intensity of these stimuli and delineates the range of levels corresponding to categorical loudness judgments for these stimuli. ABRs/MLRs were recorded simultaneously to 500- and 2,000-Hz tonebursts in 10 normal-hearing adults at levels corresponding to each listener's loudness judgments for four categories on Contour Test of Loudness...
February 2017: Seminars in Hearing
https://www.readbyqxmd.com/read/28286365/auditory-brainstem-and-middle-latency-responses-measured-pre-and-posttreatment-for-hyperacusic-hearing-impaired-persons-successfully-treated-to-improve-sound-tolerance-and-to-expand-the-dynamic-range-for-loudness-case-evidence
#9
REVIEW
Craig Formby, Peggy Korczak, LaGuinn P Sherlock, Monica L Hawley, Susan Gold
In this report of three cases, we consider electrophysiologic measures from three hyperacusic hearing-impaired individuals who, prior to treatment to expand their dynamic ranges for loudness, were problematic hearing aid candidates because of their diminished sound tolerance and reduced dynamic ranges. Two of these individuals were treated with structured counseling combined with low-level broadband sound therapy from bilateral sound generators and the third case received structured counseling in combination with a short-acting placebo sound therapy...
February 2017: Seminars in Hearing
https://www.readbyqxmd.com/read/28280753/mouse-auditory-brainstem-response-testing
#10
Omar Akil, A E Oursler, Kevin Fan, Lawrence R Lustig
The auditory brainstem response (ABR) test provides information about the inner ear (cochlea) and the central pathways for hearing. The ABR reflects the electrical responses of both the cochlear ganglion neurons and the nuclei of the central auditory pathway to sound stimulation (Zhou et al., 2006; Burkard et al., 2007). The ABR contains 5 identifiable wave forms, labeled as I-V. Wave I represents the summated response from the spiral ganglion and auditory nerve while waves II-V represent responses from the ascending auditory pathway...
March 20, 2016: Bio-protocol
https://www.readbyqxmd.com/read/28280335/nanoparticle-abraxane-possesses-impaired-proliferation-in-a549-cells-due-to-the-underexpression-of-glucosamine-6-phosphate-n-acetyltransferase-1-gnpnat1-gna1
#11
Minzhi Zhao, Haiyun Li, Yan Ma, He Gong, Shu Yang, Qiaojun Fang, Zhiyuan Hu
Abraxane (Abr), a US Food and Drug Administration-approved albumin-bound nanoparticle applied for the treatment of non-small-cell lung cancer, has been reported to be more effective than paclitaxel (PTX). To further understand the molecular mechanisms that produce this superior drug efficacy of Abr, a quantitative proteomic approach has been applied to investigate the global protein expression profiles of lung cancer cell A549 treated with Abr and PTX. Only one protein, namely, glucosamine 6-phosphate N-acetyltransferase 1 (GNA1), showed significant differential expression (P<0...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28275059/differences-in-post-injury-auditory-system-pathophysiology-after-mild-blast-and-non-blast-acute-acoustic-trauma
#12
Nicholas Race, Jesyin Lai, Riyi Shi, Edward L Bartlett
Hearing difficulties are the most commonly reported disabilities among veterans. Blast exposures during explosive events likely play a role, given their propensity to directly damage both peripheral (PAS) and central (CAS) auditory system components. Post-blast PAS pathophysiology has been well-documented in both clinical case reports and laboratory investigations. In contrast, blast-induced CAS dysfunction remains under-studied, but has been hypothesized to contribute to an array of common veteran behavioral complaints including learning, memory, communication, and emotional regulation...
March 8, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28274900/comparative-study-between-the-use-of-melatonin-and-a-solution-with-melatonin-tryptophan-and-vitamin-b6-as-an-inducer-of-spontaneous-sleep-in-children-during-an-auditory-response-test-an-alternative-to-commonly-used-sedative-drugs
#13
Antonio Della Volpe, Antonietta De Lucia, Clementina Pirozzi, Vincenzo Pastore
OBJECTIVE: An elective investigation into the early diagnosis of deafness in children under the age of 4-5 years is performed using auditory evoked potentials of auditory brainstem responses (ABRs). In case of pediatric patients, the major difficulty includes being examined during spontaneous sleep, which is complicated to obtain, especially in the age range of 12 to 72 months. Recently, melatonin has been used as a "sleep inducer" in diagnostic tests with positive results. Our aim was to evaluate the use of melatonin and of a solution containing melatonin, tryptophan, and vitamin B6 as an inducer of spontaneous sleep on repeated ABR analyses as well as to evaluate the reduction in analyses with sedative drugs in case of uncooperative patients...
March 9, 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/28271283/rotator-interval-closure-has-no-additional-effect-on-shoulder-stability-compared-to-bankart-repair-alone
#14
Eran Maman, Oleg Dolkart, Efi Kazum, Noam Rosen, Gavriel Mozes, Michael Drexler, Ofir Chechik
PURPOSE: Arthroscopic Bankart repair (ABR) provides satisfactory results for recurrent anterior shoulder instability, but the high recurrence rate post-ABR remain a concern. One of the adjunct procedures proposed to improve ABR results is arthroscopic rotator interval closure (ARIC). This study prospectively evaluated the outcomes of ABRs alone compared to combined ABR + ARIC and identified risk factors related to failure of each procedure. METHODS: Thirty-nine consecutive patients (mean age 23...
March 7, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28269101/detection-of-binaural-interaction-in-free-field-evoked-auditory-brainstem-responses-by-time-scale-representations
#15
Erik Schebsdat, Horst Hessel, Harald Seidler, Daniel J Strauss
The so called β-wave of the binaural interaction component (BIC) in auditory brainstem responses (ABR) has been shown to be an objective measure for binaural interaction (BI). This component is the arithmetical difference between the sum of the monaurally evoked ABRs and the binaurally evoked ABR. Unfortunately, these neural responses are known to be very fragile and as a result the calculated BIC. An additional issue is, that the findings of this measurement are predominantly needed in people with hearing loss who may use hearing devices like hearing aids (HA) or cochlear implants (CI), thus they are not able to use headphones (like in conventional ABR measurements) during the detection of possible BI...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268687/impact-of-mild-traumatic-brain-injury-on-auditory-brain-stem-dysfunction-in-mouse-model
#16
Reza M Amanipour, Robert D Frisina, Samantha A Cresoe, Teresa J Parsons, Xiaoxia Zhu, Cesario V Borlongan, Joseph P Walton
The auditory brainstem response (ABR) is an electrophysiological test that examines the functionality of the auditory nerve and brainstem. Traumatic brain injury (TBI) can be detected if prolonged peak latency is observed in ABR measurements, since latency measures the neural conduction time in the brainstem, and an increase in latency can be a sign of pathological lesion at the auditory brainstem level. The ABR is elicited by brief sounds that can be used to measure hearing sensitivity as well as temporal processing...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268502/quantitative-evaluation-of-alveolar-bone-resorption-on-dental-panoramic-radiographs-by-standardized-dentition-image-transformation-and-probability-estimation
#17
Chisako Muramtsu, Ryo Takahashi, Tatsuro Hayashi, Takeshi Hara, Tatsumasa Fukui, Akitoshi Katsumata, Hiroshi Fujita
Alveolar bone resorption, which can be observed on dental panoramic radiographs (DPRs), is one of the most important signs of the progression of periodontal disease. However, quantitative and consistent evaluation of alveolar bone resorption is labor intense, because of a large number of DPR examinations performed each year. In our previous study, we developed an automated scheme for detection of three lines, corresponding to an occlusion line, an alveolar line and a root apex line, to measure the alveolar bone ratio (ABR), which may be useful to dentists in early detection of periodontal disease...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28267580/carriage-of-type-ii-toxin-antitoxin-systems-by-the-growing-group-of-incx-plasmids
#18
Paula Bustamante, Jonathan R Iredell
The stable maintenance of certain plasmids in bacterial populations has contributed significantly to the current worldwide antibiotic resistance (AbR) emergency. IncX plasmids, long underestimated in this regard, have achieved recent notoriety for their roles in transmission of resistance to carbapenem and colistin, the last-line antibiotics for Gram-negative infections. Toxin-antitoxin (TA) systems contribute to stable maintenance of many AbR plasmids, and a few TA systems have been previously described in the IncX plasmids...
March 3, 2017: Plasmid
https://www.readbyqxmd.com/read/28264554/hearing-improvement-in-a-j-mice-via-the-mouse-nerve-growth-factor
#19
Lixiang Gao, Ruli Ge, Gang Xie, Dandan Yao, Ping Li, Oumei Wang, Xiufang Ma, Fengchan Han
Objectives: To investigate the otoprotective effects of mouse nerve growth factor (mNGF) in A/J mice. Methods: The mice at postnatal day 7 (P7) were randomly separated into a mNGF treated group (mNGF group) and a distilled water (for injection) treated group (control group). The mNGF dissolved in distilled water or distilled water alone was given to the mice once every other day from P7 by intramuscular injection in the hips. The otoprotective effects of mNGF in A/J mice were observed in a time course manner...
March 8, 2017: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/28262386/resident-perspectives-of-an-interactive-case-review-following-independent-didactic-study-as-a-method-of-teaching-a-pediatric-imaging-curriculum
#20
Aleksandr Rozenberg, Sachin Dheer, Levon N Nazarian, Suzanne S Long
PURPOSE: The ABR has recently changed the format of the board examination, in which the oral examination was replaced by a computer based multiple-choice test. The purpose of this study was to determine resident's perceptions of a new conference resembling the new ABR format. METHODS: Residents were requested to review a series of didactic pediatric imaging presentations prior to attending case conference. During conference, unknown cases reflecting the subject matter from the didactic presentations were presented along with multiple-choice questions...
January 14, 2017: Current Problems in Diagnostic Radiology
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