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https://www.readbyqxmd.com/read/28535485/quantification-of-residual-antibiotics-in-cow-manure-being-spread-over-agricultural-land-and-assessment-of-their-behavioral-effects-on-antibiotic-resistant-bacteria
#1
Ji-Ran Yeom, Soon-Uk Yoon, Chang-Gyun Kim
Antibiotic resistant bacteria (ARB) in livestock manure used as fertilizer and spread over agriculture land, may pose a threat to the health of humans. Considering this, the concentrations of tetracycline (TC), oxytetracycline (OTC), and sulfathiazole (STZ) in the surface soil were quantified using LC-MS. These antibiotics have been used in livestock and are found in fertilizer produced from livestock excretions. Species of ABR were identified using 16S rDNA. Soil samples were collected at depths of 0, 7, and 15 cm from farmland in Incheon (South Korea)...
May 16, 2017: Chemosphere
https://www.readbyqxmd.com/read/28530007/preventive-effect-of-cpp-acpf-paste-and-fluoride-toothpastes-against-erosion-and-erosion-plus-abrasion-%C3%A2-in-vitro-a-3d-profilometric-analysis
#2
Genaina Guimarães Soares, Pâmela Amorim Magalhães, Ana Beatriz Monteiro Fonseca, Monica Almeida Tostes, Eduardo Moreira da Silva, Thereza Christina Lopes Coutinho
PURPOSE: To evaluate the effect of CPP-ACPF paste and fluoride toothpastes on enamel subjected to erosion and erosion plus abrasion in vitro. MATERIALS AND METHODS: A total of 220 human enamel blocks were divided into eleven groups (n = 20): CPP-ACPF paste (MPP), potassium nitrate/sodium fluoride toothpaste (PE), sodium fluoride toothpaste (FD), fluoride-free toothpaste (SO) and control (erosion only with no paste or toothpastes; CO) according to the experimental design: erosion or erosion plus abrasion immediately after erosion (ERO+I-ABR) or 30 min after erosion (ERO+30min-ABR)...
May 19, 2017: Oral Health & Preventive Dentistry
https://www.readbyqxmd.com/read/28516283/developmental-window-of-sensorineural-deafness-in-biotinidase-deficient-mice
#3
Kathleen June Maheras, Kirit Pindolia, Barry Wolf, Alexander Gow
Biotinidase deficiency is an autosomal recessively inherited disorder that results in the inability to recycle the vitamin, biotin. If untreated, the disorder can result in a range of neurological and cutaneous symptoms, including sensorineural deficits and deafness. To understand early mechanistic abnormalities that may precede more generalized and nonspecific effects of metabolic deficits such as weight loss and acidosis, we have analyzed auditory brainstem responses (ABRs) in biotinidase-deficient knockout (Btd (-/-) ) mice in the periweaning period with or without dietary biotin supplementation...
May 17, 2017: Journal of Inherited Metabolic Disease
https://www.readbyqxmd.com/read/28504308/brainstem-as-a-developmental-gateway-to-social-attention
#4
Ronny Geva, Ayelet Dital, Dan Ramon, Jessica Yarmolovsky, Maor Gidron, Jacob Kuint
BACKGROUND: Evolution preserves social attention due to its key role in supporting survival. Humans are attracted to social cues from infancy, but the neurobiological mechanisms for the development of social attention are unknown. An evolutionary-based, vertical-hierarchical theoretical model of self-regulation suggests that neonatal brainstem inputs are key for the development of well-regulated social attention. METHODS: Neonates born preterm (N = 44, GA 34 w...
May 15, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28501877/association-between-sex-and-speech-auditory-brainstem-responses-in-adults-and-relationship-to-sex-hormone-levels
#5
Jinfeng Liu, Dan Wang, Xiaoting Li, Wang Ningyu
BACKGROUND The aim of this study was to investigate the association between sex and speech-ABR in adults, and its relationship to sex hormone levels. MATERIAL AND METHODS Speech-ABR were elicited with the consonant-vowel syllable (/da/) in a total of 35 adults. Reproductive hormone levels were also measured. RESULTS The transient response of the speech-ABR (waves V, A, and O) in females show a shorter latency (waves V, A and O) and a larger amplitude (waves V and A) than in males (P<0.05), except for the amplitude of peak O (P>0...
May 14, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28498265/the-effect-of-systemic-steroid-on-hearing-preservation-after-cochlear-implantation-via-round-window-approach-a-guinea-pig-model
#6
Mun Young Chang, Yoon Chan Rah, Jun Jae Choi, Shin Wook Woo, Yu-Jung Hwang, Hayden Eastwood, Stephen J O'Leary, Jun Ho Lee
HYPOTHESIS: When administered perioperatively, systemic dexamethasone will reduce the hearing loss associated with cochlear implantation (CI) performed via the round window approach. BACKGROUND: The benefits of electroacoustic stimulation have led to interest in pharmacological interventions to preserve hearing after CI. METHODS: Thirty guinea pigs were randomly divided into three experimental groups: a control group; a 3-day infusion group; and a 7-day infusion group...
May 11, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28492121/south-african-medical-students-perceptions-and-knowledge-about-antibiotic-resistance-and-appropriate-prescribing-are-we-providing-adequate-training-to-future-prescribers
#7
Sean Wasserman, Samantha Potgieter, Evan Shoul, Deborah Constant, Annemie Stewart, Marc Mendelson, Tom H Boyles
BACKGROUND: Education of medical students has been identified by the World Health Organization as an important aspect of antibiotic resistance (ABR) containment. Surveys from high-income countries consistently reveal that medical students recognise the importance of antibiotic prescribing knowledge, but feel inadequately prepared and require more education on how to make antibiotic choices. The attitudes and knowledge of South African (SA) medical students regarding ABR and antibiotic prescribing have never been evaluated...
April 25, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/28487715/overexpression-of-a-tartary-buckwheat-gene-ftbhlh3-enhances-drought-oxidative-stress-tolerance-in-transgenic-arabidopsis
#8
Pan-Feng Yao, Cheng-Lei Li, Xue-Rong Zhao, Mao-Fei Li, Hai-Xia Zhao, Jin-Ya Guo, Yi Cai, Hui Chen, Qi Wu
bHLH (basic helix-loop-helix) transcription factors play important roles in the abiotic stress response in plants, but their characteristics and functions in tartary buckwheat (Fagopyrum tataricum), a flavonoid-rich cereal crop with a strong stress tolerance, have not been fully investigated. Here, a novel bHLH gene, designated FtbHLH3, was isolated and characterized. Expression analysis in tartary buckwheat revealed that FtbHLH3 was mainly induced by polyethylene glycol 6000 (PEG6000) and abscisic acid (ABA) treatments...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28483253/the-effects-of-postnatal-phthalate-exposure-on-the-development-of-auditory-temporal-processing-in-rats
#9
Bong Jik Kim, Jungyoon Kim, Vanhnansy Keoboutdy, Ho-Jang Kwon, Seung-Ha Oh, Jae Yun Jung, Il Yong Park, Ki Chung Paik
OBJECTIVE: The central auditory pathway is known to continue its development during the postnatal critical periods and is shaped by experience and sensory inputs. Phthalate, a known neurotoxic material, has been reported to be associated with attention deficits in children, impacting many infant neurobehaviors. The objective of this study was to investigate the potential effects of neonatal phthalate exposure on the development of auditory temporal processing. METHODS: Neonatal Sprague-Dawley rats were randomly assigned into two groups: The phthalate group (n = 6), and the control group (n = 6)...
June 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28474118/genome-wide-analysis-identifies-chickpea-cicer-arietinum-heat-stress-transcription-factors-hsfs-responsive-to-heat-stress-at-the-pod-development-stage
#10
Parameswaran Chidambaranathan, Prasanth Tej Kumar Jagannadham, Viswanathan Satheesh, Deshika Kohli, Santosh Halasabala Basavarajappa, Bharadwaj Chellapilla, Jitendra Kumar, Pradeep Kumar Jain, R Srinivasan
The heat stress transcription factors (Hsfs) play a prominent role in thermotolerance and eliciting the heat stress response in plants. Identification and expression analysis of Hsfs gene family members in chickpea would provide valuable information on heat stress responsive Hsfs. A genome-wide analysis of Hsfs gene family resulted in the identification of 22 Hsf genes in chickpea in both desi and kabuli genome. Phylogenetic analysis distinctly separated 12 A, 9 B, and 1 C class Hsfs, respectively. An analysis of cis-regulatory elements in the upstream region of the genes identified many stress responsive elements such as heat stress elements (HSE), abscisic acid responsive element (ABRE) etc...
May 4, 2017: Journal of Plant Research
https://www.readbyqxmd.com/read/28473856/recovery-of-abnormal-abr-in-neonates-and-infants-at-risk-of-hearing-loss
#11
Ioannis Psarommatis, Charalampos Voudouris, Ioannis Kapetanakis, Faselida Athanasiadi, Konstantinos Douros
The purpose of this retrospective study is to present the clinical experience of a single institution on the recovery of ABR thresholds in a large population of neonates and infants at risk of hearing loss. Potential prognostic factors associated with this phenomenon were also investigated. Out of 2248 high risk infants, 384 had abnormal ABR at initial hearing evaluation and 168 of them had absent ABR or a threshold ≥80 dBnHL. From this subgroup, a significant percentage showed complete or partial recovery on reexamination (32...
2017: International Journal of Otolaryngology
https://www.readbyqxmd.com/read/28473643/g6pd-deficiency-does-not-affect-the-cytosolic-glutathione-or-thioredoxin-antioxidant-defense-in-mouse-cochlea
#12
White Karessa, Mi-Jung Kim, Dalian Ding, Chul Han, Hyo-Jin Park, Zaimary Meneses, Masaru Tanokura, Paul Linser, Richard Salvi, Shinichi Someya
Glucose-6-phosphate dehydrogenase (G6PD) is the first and rate-limiting enzyme of the pentose phosphate pathway; it catalyzes the conversion of glucose-6-phosphate to 6-phosphogluconate and NADP(+) to NADPH, and is thought to be the principal source of NADPH for the cytosolic glutathione and thioredoxin antioxidant defense systems. We investigated the roles of G6PD in the cytosolic antioxidant defense in the cochlea of G6pd hypomorphic mice that were backcrossed onto normal-hearing CBA/CaJ mice. Young G6pd-deficient mice displayed a significant decrease in cytosolic G6PD protein levels and activities in the inner ears...
May 4, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28445829/the-role-of-peu-mir164-and-its-target-penac-genes-in-response-to-abiotic-stress-in-populus-euphratica
#13
Xin Lu, Hui Dun, Conglong Lian, Xiaofei Zhang, Weilun Yin, Xinli Xia
Plant miR164 family is highly conserved and miR164 members regulate conserved targets belonging to NAC transcription factors. Our previous studies have revealed that peu-miR164a-e and its target gene POPTR_0007s08420 participate in abiotic stress response in Populus euphratica according to deep sequencing and degradome sequencing. In this study, miR164 family comprises six members that generate two mature products (miR164a-e and miR164f) and target seven NAC genes in P. euphratica. Co-expression in Nicotiana benthamiana and 5' RACE confirmed that peu-miR164 directs PeNAC070, PeNAC012 and PeNAC028 mRNAs cleavage...
April 8, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/28443060/the-vestibular-implant-hearing-preservation-during-intralabyrinthine-electrode-insertion-a-case-report
#14
Raymond van de Berg, Florence Lucieer, Nils Guinand, Joost van Tongeren, Erwin George, Jean-Philippe Guyot, Herman Kingma, Marc van Hoof, Yasin Temel, Jacobus van Overbeeke, Angelica Perez-Fornos, Robert Stokroos
OBJECTIVE: The vestibular implant seems feasible as a clinically useful device in the near future. However, hearing preservation during intralabyrinthine implantation remains a challenge. It should be preserved to be able to treat patients with bilateral vestibulopathy and (partially) intact hearing. This case study investigated the feasibility of hearing preservation during the acute phase after electrode insertion in the semicircular canals. METHODS: A 40-year-old woman with normal hearing underwent a translabyrinthine approach for a vestibular schwannoma Koos Grade IV...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28443033/high-gama-aminobutyric-acid-contents-involved-in-abamectin-resistance-and-predation-an-interesting-phenomenon-in-spider-mites
#15
Zhifeng Xu, Yanchao Liu, Peng Wei, Kaiyang Feng, Jinzhi Niu, Guangmao Shen, Wencai Lu, Wei Xiao, Jinjun Wang, Guy J Smagghe, Qiang Xu, Lin He
Abamectin has been widely used as an insecticide/acaricide for more than 30 years because of its superior bioactivity. Recently, an interesting phenomenon was identified in the carmine spider mite, Tetranychus cinnabarinus, an important pest in agriculture. The gamma aminobutyric acid (GABA) contents in a laboratory abamectin resistant strain of T. cinnabarinus (AbR) were significantly increased. Decreases in activity and mRNA expression of GABA transaminase (GABA-T) were responsible for GABA accumulation in AbR mites...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28434845/abr-subspecialty-certifications-in-hospice-and-palliative-medicine-and-pain-medicine
#16
Paul E Wallner, Kay H Vydareny, Anne C Roberts
The ACGME currently approves fellowship training in 11 subspecialties of radiology, and the ABR currently offers six subspecialty certificates (vascular interventional radiology will be phased out in 2017) to its primary certificate holders. Four of the ABR-sponsored or co-sponsored subspecialties have been available to ABR diplomates for more than 18 years, but two-hospice and palliative medicine and pain medicine-are relatively new. The nature of specialty and subspecialty certificate development and details related to these two specific programs will be considered...
April 20, 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28434389/evaluation-of-the-protective-effect-of-botulinum-toxin-type-a-injection-on-otitis-media-with-effusion
#17
Ömer Faruk Çalım, Yavuz Selim Yıldırım, Remzi Doğan, Selhattin Tuğrul, Özge Gedik, Orhan Özturan
OBJECTIVE: This study makes an analysis of the effect of Botulinum toxin type A on otitis media with effusion in rats. METHOD: As part of the study, 24 male Wistar Albino rats were divided into three groups: Group 1: Botulinum toxin Type A and Histamıne (intratympanic 0.2 ml = 20 unit BTA); Group 2: Saline and Histamine (intratympanic 0.2 ml 0.9%); Group 3: Histamine (intratympanic 0.2 ml). Histamine (intratympanic 0.2 ml) was administered into the right ear for all groups...
April 22, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28432353/severe-hearing-loss-and-outer-hair-cell-death-in-homozygous-foxo3-knockout-mice-after-moderate-noise-exposure
#18
Felicia Gilels, Stephen T Paquette, Holly J Beaulac, Anwen Bullen, Patricia M White
Noise induced hearing loss (NIHL) is a disease that affects millions of Americans. Identifying genetic pathways that influence recovery from noise exposure is an important step forward in understanding NIHL. The transcription factor Foxo3 integrates the cellular response to oxidative stress and plays a role in extending lifespan in many organisms, including humans. Here we show that Foxo3 is required for auditory function after noise exposure in a mouse model system, measured by ABR. Absent Foxo3, outer hair cells are lost throughout the middle and higher frequencies...
April 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28420277/device-optimised-chirp-stimulus-for-abr-measurements-with-an-active-middle-ear-implant
#19
Mario Cebulla, Ute Geiger, Rudolf Hagen, Andreas Radeloff
OBJECTIVE: Active middle ear implants are widely used to treat adults and children with sensorineural, conductive, or mixed hearing loss. Currently, there is no adequate method to determine the performance of active middle ear implant systems. DESIGN: The proposed method is based on measuring the auditory brainstem response while stimulating the hearing system via the active middle ear implant (Vibrant Soundbridge(TM), VSB; MEDEL, Austria). The acoustic stimulation was achieved via an optimised chirp stimulus (CE-Chirp), implemented in the Eclipse system (Interacoustics, Denmark)...
April 19, 2017: International Journal of Audiology
https://www.readbyqxmd.com/read/28415901/sloping-abr-baselines-and-the-ecg-myogenic-artefact
#20
Guy Lightfoot
OBJECTIVE: To investigate the possibility that a sloping baseline in an ABR recording has its origins in cardiac activity and if so, identify how it is expressed. DESIGN: The effect of ECG removal on the averaged ABR was investigated at two artefact rejection levels. STUDY SAMPLE: Ten 1-minute records of raw EEG containing ABR responses but contaminated with cardiac activity were recorded from babies under 12 weeks of age and re-averaged using two artefact rejection levels...
April 18, 2017: International Journal of Audiology
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