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https://www.readbyqxmd.com/read/28432883/sagittal-plane-joint-kinetics-during-stair-ascent-in-patients-with-peripheral-arterial-disease-and-intermittent-claudication
#1
Stephanie L King, Natalie Vanicek, Thomas D O'Brien
Stair negotiation poses a substantial physical demand on the musculoskeletal system and this challenging task can place individuals at risk of falls. Peripheral arterial disease (PAD) can cause intermittent claudication (IC) pain in the calf and results in altered gait mechanics during level walking. However, whether those with PAD-IC adopt alternate strategies to climb stairs is unknown. Twelve participants with PAD-IC (six bilateral and six unilateral) and 10 healthy controls were recruited and instructed to ascend a five-step staircase whilst 3D kinematic data of the lower-limbs were recorded synchronously with kinetic data from force plates embedded into the staircase on steps two and three...
March 28, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28432504/3t-mri-of-the-knee-with-optimised-isotropic-3d-sequences-accurate-delineation-of-intra-articular-pathology-without-prolonged-acquisition-times
#2
Osamah M Abdulaal, Louise Rainford, Peter MacMahon, Eoin Kavanagh, Marie Galligan, James Cashman, Allison McGee
OBJECTIVES: To investigate optimised isotropic 3D turbo spin echo (TSE) and gradient echo (GRE)-based pulse sequences for visualisation of articular cartilage lesions within the knee joint. METHODS: Optimisation of experimental imaging sequences was completed using healthy volunteers (n=16) with a 3-Tesla (3T) MRI scanner. Imaging of patients with knee cartilage abnormalities (n=57) was then performed. Acquired sequences included 3D proton density-weighted (PDW) TSE (SPACE) with and without fat-suppression (FS), and T2*W GRE (TrueFISP) sequences, with acquisition times of 6:51, 6:32 and 5:35 min, respectively...
April 21, 2017: European Radiology
https://www.readbyqxmd.com/read/28432420/sex-differences-in-neuromuscular-function-after-repeated-eccentric-contractions-of-the-knee-extensor-muscles
#3
Andrea Lee, Jake Baxter, Claire Eischer, Matt Gage, Sandra Hunter, Tejin Yoon
PURPOSE: This study examined the mechanisms for force and power reduction during and up to 48 h after maximal eccentric contractions of the knee extensor muscles in young men and women. METHODS: 13 men (22.8 ± 2.6 years) and 13 women (21.6 ± 2.2 years) performed 150 maximal effort eccentric contractions (5 sets of 30) with the knee extensor muscles at 60° s(-1). Maximal voluntary isometric contractions (MVIC) and maximal voluntary concentric contractions (MVCC) were performed before and after the 150 eccentric contractions...
April 21, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28432403/bone-marrow-fat-content-in-70-adolescent-girls-with-anorexia-nervosa-magnetic-resonance-imaging-and-magnetic-resonance-spectroscopy-assessment
#4
Kirsten Ecklund, Sridhar Vajapeyam, Robert V Mulkern, Henry A Feldman, Jennifer M O'Donnell, Amy D DiVasta, Catherine M Gordon
BACKGROUND: Adolescents and women with anorexia nervosa have increased bone marrow fat and decreased bone formation, at least in part due to hormonal changes leading to preferential stem cell differentiation to adipocytes over osteoblasts. OBJECTIVE: The purpose of this study was to evaluate marrow fat content and correlate with age and disease severity using knee MRI with T1 relaxometry (T1-R) and MR spectroscopy (MRS) in 70 adolescents with anorexia nervosa. MATERIALS AND METHODS: We enrolled 70 girls with anorexia nervosa who underwent 3-T knee MRI with coronal T1-W images, T1-R and single-voxel proton MRS at 30 and 60 ms TE...
April 22, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28432395/the-magnetic-resonance-imaging-appearance-of-the-anterolateral-ligament-of-the-knee-in-association-with-anterior-cruciate-rupture
#5
Jonathan D Kosy, Peter J Schranz, Anish Patel, Rahul Anaspure, Vipul I Mandalia
OBJECTIVE: The magnetic resonance imaging (MRI) appearance of the anterolateral ligament (ALL) has been described. However, the appearance of this structure and injury, in the presence of anterior cruciate ligament (ACL) injury, is less well defined. We studied the incidence of injury to the ALL and the pattern of this injury on MRI. MATERIALS AND METHODS: Following Institutional Review Board approval, a retrospective study of 375 consecutive MRI studies was performed...
April 21, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28431865/statin-use-and-other-factors-associated-with-mortality-after-major-lower-extremity-amputation
#6
Charles DeCarlo, Larry Scher, Saadat Shariff, John Phair, Evan Lipsitz, Karan Garg
OBJECTIVE: Above-knee amputations (AKAs) and below-knee amputations (BKAs) are associated with high postoperative mortality rates. In this study, we examined factors associated with 30-day, 90-day, and 1-year mortality in patients who underwent a major lower extremity amputation. METHODS: We queried a prospectively collected institutional database for all patients who underwent AKA or BKA with primary or secondary closure, during a 5-year period, between November 2009 and November 2014...
April 18, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28431747/effects-of-vibration-training-in-reducing-risk-of-slip-related-falls-among-young-adults-with-obesity
#7
Feng Yang, Jose Munoz, Long-Zhu Han, Fei Yang
This study examined the effects of controlled whole-body vibration training on reducing risk of slip-related falls in people with obesity. Twenty-three young adults with obesity were randomly assigned into either the vibration or placebo group. The vibration and placebo groups respectively received 6-week vibration and placebo training on a side-alternating vibration platform. Before and after the training, the isometric knee extensors strength capacity was measured for the two groups. Both groups were also exposed to a standardized slip induced by a treadmill during gait prior to and following the training...
April 9, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28431618/muscle-strength-and-power-in-persons-with-multiple-sclerosis-a-systematic-review-and-meta-analysis
#8
REVIEW
Mlk Jørgensen, U Dalgas, I Wens, L G Hvid
BACKGROUND: Multiple sclerosis (MS) is a chronic disease in the central nervous system which causes a number of physical symptoms including impairments of muscle mechanical function (muscle strength, muscle power and explosive muscle strength (~rate of force development, RFD)). However, a full overview of the existing knowledge regarding muscle mechanical function in persons with MS (PwMS) is still pending. OBJECTIVES: To systematically review 1) the psychometric properties of isokinetic dynamometry testing in PwMS, and 2) studies comparing muscle mechanical function in PwMS to matched healthy controls (HC)...
May 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28431586/expression-of-calcitonin-gene-related-peptide-in-the-infrapatellar-fat-pad-in-knee-osteoarthritis-patients
#9
Jun Aikawa, Kentaro Uchida, Shotaro Takano, Gen Inoue, Atsushi Minatani, Masayuki Miyagi, Dai Iwase, Hiroyuki Sekiguchi, Manabu Mukai, Masashi Takaso
BACKGROUND: The infrapatellar fat pad (IPFP) has been implicated as a possible source of osteoarthritis (OA) development and knee pain due to the production of inflammatory mediators and the existence of nerve fibers within this structure. Calcitonin gene-related peptide (CGRP) is a vasodilatory neuropeptide that is localized to joint tissues and has recently been implicated in the development of knee OA and OA pain. To date, however, the expression levels of CGRP in the IPFP of human knee OA patients have not been examined...
April 21, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28431561/the-evaluation-of-the-role-of-medial-collateral-ligament-maintaining-knee-stability-by-a-finite-element-analysis
#10
Dong Ren, Yueju Liu, Xianchao Zhang, Zhaohui Song, Jian Lu, Pengcheng Wang
BACKGROUND: A three-dimensional finite element model (FEM) of the knee joint was established to analyze the biomechanical functions of the superficial and deep medial collateral ligaments (MCLs) of knee joints and to investigate the treatment of the knee medial collateral ligament injury. METHODS: The right knee joint of a healthy male volunteer was subjected to CT and MRI scans in the extended position. The scanned data were imported into MIMICS, Geomagic, and ANSYS software to establish a three-dimensional FEM of the human knee joint...
April 21, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28431220/contribution-of-ankle-foot-orthosis-moment-in-regulating-ankle-and-knee-motions-during-gait-in-individuals-post-stroke
#11
Toshiki Kobayashi, Michael S Orendurff, Madeline L Singer, Fan Gao, K Bo Foreman
BACKGROUND: Ankle-foot orthosis moment resisting plantarflexion has systematic effects on ankle and knee joint motion in individuals post-stroke. However, it is not known how much ankle-foot orthosis moment is generated to regulate their motion. The aim of this study was to quantify the contribution of an articulated ankle-foot orthosis moment to regulate ankle and knee joint motion during gait in individuals post-stroke. METHODS: Gait data were collected from 10 individuals post-stroke using a Bertec split-belt instrumented treadmill and a Vicon 3-dimensional motion analysis system...
April 8, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28431145/long-term-effects-of-a-lifestyle-intervention-and-oral-glucosamine-sulphate-in-primary-care-on-incident-knee-oa-in-overweight-women
#12
Bastiaan C de Vos, Marieke L A Landsmeer, Marienke van Middelkoop, Edwin H G Oei, Marjolein Krul, Sita M A Bierma-Zeinstra, Jos Runhaar
Objectives.: The present study was designed to evaluate the effect of a lifestyle intervention aimed to reduce body weight and of oral glucosamine sulphate on the incidence of knee osteoarthritis (OA) after 6-7 years in a population of middle-aged, overweight women, without knee OA at baseline. Methods.: The Prevention of knee Osteoarthritis in Overweight Females study, ISRCTN42823086, was a randomized controlled trial with a 2 × 2 factorial design. Four hundred and seven women aged 50-60 years with a BMI of ⩾27 kg/m 2 and free of knee OA were randomized...
April 20, 2017: Rheumatology
https://www.readbyqxmd.com/read/28431129/cooled-radiofrequency-ablation-of-the-genicular-nerves-for-chronic-pain-due-to-knee-osteoarthritis-six-month-outcomes
#13
Zachary L McCormick, Marc Korn, Rajiv Reddy, Austin Marcolina, David Dayanim, Ryan Mattie, Daniel Cushman, Meghan Bhave, Robert J McCarthy, Dost Khan, Geeta Nagpal, David R Walega
Objective. : Determine outcomes of cooled radiofrequency ablation (C-RFA) of the genicular nerves for treatment of chronic knee pain due to osteoarthritis (OA). Design. : Cross-sectional survey. Setting.:  Academic pain medicine center. Subjects.:  Consecutive patients with knee OA and 50% or greater pain relief following genicular nerve blocks who underwent genicular nerve C-RFA. Methods.:  Survey administration six or more months after C-RFA...
April 19, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28431086/dynamic-ultrasound-imaging-for-quadriceps-tendon-impingement-in-a-patient-with-anterior-knee-pain
#14
Muhammad Dughbaj, Diaa Shehab, Levent Özçakar
No abstract text is available yet for this article.
April 18, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28430716/simultaneous-multislice-accelerated-turbo-spin-echo-magnetic-resonance-imaging-comparison-and-combination-with-in-plane-parallel-imaging-acceleration-for-high-resolution-magnetic-resonance-imaging-of-the-knee
#15
Jan Fritz, Benjamin Fritz, Jialu Zhang, Gaurav K Thawait, Dharmdev H Joshi, Li Pan, Dingxin Wang
PURPOSE: We prospectively quantified the signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of integrated parallel acquisition technique (PAT) and simultaneous multislice (SMS) acceleration and various combinations thereof, and we further compared two 4-fold-accelerated (PAT2-SMS2) high-resolution turbo spin echo (TSE) magnetic resonance imaging (MRI) protocols of the knee against a clinical 2-fold-accelerated (PAT2-SMS1) TSE standard. MATERIALS AND METHODS: Institutional review board approval was obtained, and all subjects gave informed consent...
April 20, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28430692/lack-of-association-between-the-use-of-nerve-blockade-and-the-risk-of-postoperative-chronic-opioid-use-among-patients-undergoing-total-knee-arthroplasty-evidence-from-the-marketscan-database
#16
Eric C Sun, Brian T Bateman, Stavros G Memtsoudis, Mark D Neuman, Edward R Mariano, Laurence C Baker
BACKGROUND: Total knee arthroplasty (TKA) is associated with high rates of prolonged opioid use after surgery (10%-34%). By decreasing opioid use in the immediate postoperative period, perioperative nerve blockade has been hypothesized to decrease the risk of persistent opioid use. METHODS: Using health care utilization data, we constructed a sample of 120,080 patients undergoing TKA between 2002 and 2012 and used billing data to identify the utilization of peripheral or neuraxial blockade...
April 19, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28430581/association-between-en1-rs4144782-and-susceptibility-of-knee-osteoarthritis-a-case-control-study
#17
Li Haohuan, Zhang Xiaolong, Cao Yiping, Hu Song, Peng Fei, Zhou Jianlin, Li Jianping
Osteoarthritis (OA) is a complex disease that affects the whole joint, resulting from the combined influence of biomechanical factors and genetic factors. The heritable component for primary OA accounts for about 60% of variation in population liability to the disease. So far, genome-wide association studies (GWAS) and candidate gene studies have established many OA-related loci. However, these findings account for only a rather small fraction of the genetic component. To further reveal the genetic architecture of OA, we conducted this case-control study to explore the association of locus EN1 rs4144782 and knee OA susceptibility in a Chinese population...
April 5, 2017: Oncotarget
https://www.readbyqxmd.com/read/28429967/knee-arthroscopic-surgery-in-middle-aged-patients-with-meniscal-symptoms-a-3-year-follow-up-of-a-prospective-randomized-study
#18
Håkan Gauffin, Sofi Sonesson, Andreas Meunier, Henrik Magnusson, Joanna Kvist
BACKGROUND: The optimal treatment for middle-aged patients with knee pain and meniscal lesions has been extensively debated. Most previous studies have revealed only short-term beneficial results of knee arthroscopic surgery. The authors have previously shown a positive benefit of knee arthroscopic surgery and an exercise program after 1 year when compared with an exercise program alone. PURPOSE: To evaluate if knee arthroscopic surgery combined with an exercise program provided an additional long-term benefit after 3 years compared with an exercise program alone in middle-aged patients with meniscal symptoms...
April 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28429403/accuracy-of-computed-tomographic-arthrography-for-assessment-of-articular-cartilage-defects-in-the-ovine-stifle
#19
Fanny Hontoir, Peter Clegg, Vincent Simon, Nathalie Kirschvink, Jean-Francois Nisolle, Jean-Michel Vandeweerd
Articular cartilage defects are one of the features of osteoarthritis in animals and humans. Early detection of cartilage defects is a challenge in clinical veterinary practice and also in translational research studies. An accurate, diagnostic imaging method would be desirable for detecting and following up lesions in specific anatomical regions of the articular surface. The current prospective experimental study aimed to describe the accuracy of computed tomographic arthrography (CTA) for detecting cartilage defects in a common animal model used for osteoarthritis research, the ovine stifle (knee, femoropatellar/femorotibial) joint...
April 20, 2017: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/28429341/hyalone%C3%A2-in-the-treatment-of-symptomatic-hip-oa-data-from-the-antiage-register-seven-years-of-observation
#20
A Migliore, U Massafra, B Frediani, E Bizzi, E Sinelnikov Yzchaki, G Gigliucci, M Cassol, S Tormenta
OBJECTIVE: Several studies on knee osteoarthritis suggest that the intra-articular administration of hyaluronic acid products may be a relevant option in the management of patients with persistent pain. The aim of this study is to report the data of efficacy of US-guided HyalOne®/Hyalubrix® 60 injections in a large population of patients with hip osteoarthritis, repeated at least 2 times per year for up to seven years. PATIENTS AND METHODS: This is a prospective, post-marketing, cohort study...
April 2017: European Review for Medical and Pharmacological Sciences
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