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https://www.readbyqxmd.com/read/29149859/medicinal-plants-used-by-women-in-mecca-urban-muslim-and-gendered-knowledge
#1
Afnan Alqethami, Julie A Hawkins, Irene Teixidor-Toneu
BACKGROUND: This study explores medicinal plant knowledge and use among Muslim women in the city of Mecca, Saudi Arabia. Ethnobotanical research in the region has focused on rural populations and male herbal healers in cities, and based on these few studies, it is suggested that medicinal plant knowledge may be eroding. Here, we document lay, female knowledge of medicinal plants in an urban centre, interpreting findings in the light of the growing field of urban ethnobotany and gendered knowledge and in an Islamic context...
November 17, 2017: Journal of Ethnobiology and Ethnomedicine
https://www.readbyqxmd.com/read/29147943/unusual-appearance-of-a-cardiac-mass
#2
Wern Yew Ding, Mohammed Meah, Richard Hawkins, Paul Mann
No abstract text is available yet for this article.
November 17, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/29144182/plasma-lyte-148-vs-hartmann-s-solution-for-cardiopulmonary-bypass-pump-prime-a-prospective-double-blind-randomized-trial
#3
Laurence Weinberg, Elizabeth Chiam, James Hooper, Frank Liskaser, Angela Kim Hawkins, Denise Massie, Andrew Ellis, Chong O Tan, David Story, Rinaldo Bellomo
BACKGROUND: The mechanisms of acid-base changes during cardiopulmonary bypass (CPB) remain unclear. We tested the hypothesis that, when used as CPB pump prime solutions, Plasma-Lyte 148 (PL) and Hartmann's solution (HS) have differential mechanisms of action in their contribution to acid-base changes. METHODS: We performed a prospective, double-blind, randomized trial in adult patients undergoing elective cardiac surgery with CPB. Participants received a CPB prime solution of 2000 mL, with either PL or HS...
November 1, 2017: Perfusion
https://www.readbyqxmd.com/read/29142973/renal-amyloidosis-associated-with-5-novel%C3%A2-variants-in-the-fibrinogen-a-alpha-chain-protein
#4
Dorota Rowczenio, Maria Stensland, Gustavo A de Souza, Erik H Strøm, Janet A Gilbertson, Graham Taylor, Nigel Rendell, Shane Minogue, Yvonne A Efebera, Helen J Lachmann, Ashutosh D Wechalekar, Philip N Hawkins, Ketil R Heimdal, Kristian Selvig, Inger K Lægreid, Nathalie Demoulin, Selda Aydin, Julian D Gillmore, Tale N Wien
Introduction: Fibrinogen A alpha chain amyloidosis is an autosomal dominant disease associated with mutations in the fibrinogen A alpha chain (FGA) gene, and it is the most common cause of hereditary renal amyloidosis in the UK. Patients typically present with kidney impairment and progress to end-stage renal disease over a median time of 4.6 years. Methods: Six patients presented with proteinuria, hypertension, and/or lower limb edema and underwent detailed clinical and laboratory investigations...
May 2017: KI Reports
https://www.readbyqxmd.com/read/29141871/potential-approaches-to-prevent-hypoglycemia-associated-autonomic-failure
#5
REVIEW
Eric Lontchi-Yimagou, Jee Young You, Michelle Carey, Ilan Gabriely, Harry Shamoon, Meredith Hawkins
Clear health benefits are associated with intensive glucose control in type 1 diabetes mellitus (T1DM). However, maintaining near-normal glycemia remains an elusive goal for many patients, in large part owing to the risk of severe hypoglycemia. In fact, recurrent episodes of hypoglycemia lead to 'hypoglycemia-associated autonomic failure' (HAAF), characterized by defective counter-regulatory responses to hypoglycemia. Extensive studies to understand the mechanisms underlying HAAF have revealed multiple potential etiologies, suggesting various approaches to prevent the development of HAAF...
November 14, 2017: Journal of Investigative Medicine: the Official Publication of the American Federation for Clinical Research
https://www.readbyqxmd.com/read/29140773/reply-to-d-t-w-jones-et-al
#6
Uri Tabori, Eric Bouffet, Cynthia E Hawkins
No abstract text is available yet for this article.
November 15, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29138053/recessive-mutation-in-fam83g-associated-with-palmoplantar-keratoderma-and-exuberant-scalp-hair
#7
Thiviyani Maruthappu, Lisa A McGinty, Diana C Blaydon, Benjamin Fell, Arto Määttä, Rebecca Duit, Tim Hawkins, Kristin M Braun, Michael A Simpson, Edel A O'Toole, David P Kelsell
No abstract text is available yet for this article.
November 11, 2017: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/29135583/effect-of-immediate-initiation-of-antiretroviral-treatment-on-the-risk-of-acquired-hiv-drug-resistance
#8
Sara Lodi, Huldrych F Günthard, David Dunn, Federico Garcia, Roger Logan, Sophie Jose, Heiner C Bucher, Alexandra U Scherrer, Marie-Paule Schneider, Matthias Egger, Tracy R Glass, Peter Reiss, Ard van Sighem, T Sonia Boender, Andrew N Phillips, Kholoud Porter, David Hawkins, Santiago Moreno, Susana Monge, Dimitrios Paraskevis, Metallidis Simeon, Georgia Vourli, Caroline Sabin, Miguel A Hernán
OBJECTIVE: We estimated and compared the risk of clinically identified acquired drug resistance under i) immediate initiation (the currently recommended ART initiation strategy), ii) initiation with CD4 < 500, and iii) initiation with CD4 < 350 cells/mm. DESIGN: Cohort study based on routinely collected data from the HIV-CAUSAL Collaboration. METHODS: For each individual, baseline was the earliest time when all eligibility criteria (ART-naïve, AIDS-free, and others) were met after 1999...
November 10, 2017: AIDS
https://www.readbyqxmd.com/read/29135321/interactivity-presence-and-targeted-patient-care-mapping-e-health-intervention-effects-over-time-for-cancer-patients-with-depression
#9
Sojung Claire Kim, Bret R Shaw, Dhavan V Shah, Robert P Hawkins, Suzanne Pingree, Fiona M McTavish, David H Gustafson
This study examined the interplay of depression and different types of e-health interventions on breast cancer patients' perceived healthcare competence, emotional processing, and social well-being over time. The three e-health interventions--Internet Only as a control condition, CHESS (Comprehensive Health Enhancement Support System) Only, and CHESS with a Human Mentor, a cancer information specialist--provided varying degrees of interactivity and presence. A total of 328 women with breast cancer participated in one of the three interventions for a 6-month period...
November 14, 2017: Health Communication
https://www.readbyqxmd.com/read/29134018/a-gene-tree-test-of-the-traditional-taxonomy-of-american-deer-the-importance-of-voucher-specimens-geographic-data-and-dense-sampling
#10
Eliécer E Gutiérrez, Kristofer M Helgen, Molly M McDonough, Franziska Bauer, Melissa T R Hawkins, Luis A Escobedo-Morales, Bruce D Patterson, Jesús E Maldonado
The taxonomy of American deer has been established almost entirely on the basis of morphological data and without the use of explicit phylogenetic methods; hence, phylogenetic analyses including data for all of the currently recognized species, even if based on a single gene, might improve current understanding of their taxonomy. We tested the monophyly of the morphology-defined genera and species of New World deer (Odocoileini) with phylogenetic analyses of mitochondrial DNA sequences. This is the first such test conducted using extensive geographic and taxonomic sampling...
2017: ZooKeys
https://www.readbyqxmd.com/read/29133263/prospective-evaluation-of-pasireotide-in-patients-undergoing-pancreaticoduodenectomy-the-washington-university-experience
#11
Ismael Dominguez-Rosado, Ryan C Fields, Cheryl A Woolsey, Gregory Williams, Timothy A Horwedel, J Bart Rose, Chet W Hammill, Maria B Doyle, William C Chapman, Steven M Strasberg, William G Hawkins, Dominic E Sanford
BACKGROUND: Pasireotide is a newer generation somatostatin analogue which led to a significant reduction in pancreatic fistula after pancreatectomy in a single-center randomized controlled trial. We sought to determine if pasireotide reduces the incidence of pancreatic fistula and other complications following pancreaticoduodenectomy at our high volume center. STUDY DESIGN: All patients between April 2011 and January 2017 undergoing pancreaticoduodenectomy were prospectively followed and their complications graded using the Modified Accordion Grading System (MAGS) in our institutional complications database...
November 10, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/29131427/optimal-fabrication-methods-for-miniature-coplanar-ion-traps
#12
Trevor K Decker, Yuan Tian, Joshua S McClellan, Linsey Bennett, Stephen A Lammert, Daniel E Austin, Aaron R Hawkins
RATIONALE: Ion trap mass spectrometers are beneficial due to their intrinsic sensitivity and specificity. Therefore, a portable version for in situ analysis of various compounds is very attractive. Miniaturization of ion traps is paramount to the portability of said mass spectrometers. METHODS: We developed an optimized design for a planar linear ion trap mass spectrometer, consisting of two trapping plates with photolithographically patterned electrodes. Each plate is constructed using a machined glass substrate and standard microfabrication procedures...
November 13, 2017: Rapid Communications in Mass Spectrometry: RCM
https://www.readbyqxmd.com/read/29128442/urinary-excretion-of-aluminium-and-silicon-in-secondary-progressive-multiple-sclerosis
#13
Krista Jones, Caroline Linhart, Clive Hawkins, Christopher Exley
BACKGROUND: Progressive multiple sclerosis is a chronic autoimmune condition of unknown aetiology and few therapeutic options. Human exposure to aluminium has been linked with multiple sclerosis and affected individuals are known to excrete unusually high amounts of aluminium in their urine. Silicon-rich mineral waters facilitate the removal of aluminium from the body in urine and herein we have tested their efficacy in affecting urinary excretion of aluminium in individuals diagnosed with secondary progressive multiple sclerosis (SPMS)...
November 1, 2017: EBioMedicine
https://www.readbyqxmd.com/read/29127345/the-synthetic-neuroactive-steroid-sge-516-reduces-seizure-burden-and-improves-survival-in-a-dravet-syndrome-mouse-model
#14
Nicole A Hawkins, Michael Lewis, Rebecca S Hammond, James J Doherty, Jennifer A Kearney
Dravet syndrome is an infant-onset epileptic encephalopathy with multiple seizure types that are often refractory to conventional therapies. Treatment with standard benzodiazepines like clobazam, in combination with valproate and stiripentol, provides only modest seizure control. While benzodiazepines are a first-line therapy for Dravet syndrome, they are limited by their ability to only modulate synaptic receptors. Unlike benzodiazepines, neuroactive steroids potentiate a wider-range of GABAA receptors. The synthetic neuroactive steroid SGE-516 is a potent positive allosteric modulator of both synaptic and extrasynaptic GABAA receptors...
November 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29124018/improved-high-throughput-quantification-of-luminescent-microplate-assays-using-a-common-western-blot-imaging-system
#15
Liam J Hawkins, Kenneth B Storey
Common Western-blot imaging systems have previously been adapted to measure signals from luminescent microplate assays. This can be a cost saving measure as Western-blot imaging systems are common laboratory equipment and could substitute a dedicated luminometer if one is not otherwise available. One previously unrecognized limitation is that the signals captured by the cameras in these systems are not equal for all wells. Signals are dependent on the angle of incidence to the camera, and thus the location of the well on the microplate...
2017: MethodsX
https://www.readbyqxmd.com/read/29122509/exploring-social-media-in-health-care-beyond-its-pervasiveness
#16
C Matthew Hawkins, Ruth C Carlos
No abstract text is available yet for this article.
November 1, 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29121162/the-effect-of-adaptive-nonlinear-frequency-compression-on-phoneme-perception
#17
Danielle Glista, Marianne Hawkins, Andrea Bohnert, Julia Rehmann, Jace Wolfe, Susan Scollie
Purpose: This study implemented a fitting method, developed for use with frequency lowering hearing aids, across multiple testing sites, participants, and hearing aid conditions to evaluate speech perception with a novel type of frequency lowering. Method: A total of 8 participants, including children and young adults, participated in real-world hearing aid trials. A blinded crossover design, including posttrial withdrawal testing, was used to assess aided phoneme perception...
November 9, 2017: American Journal of Audiology
https://www.readbyqxmd.com/read/29119062/xanthine-oxidase-contributes-to-sustained-airway-epithelial-oxidative-stress-after-scald-burn
#18
Sam Jacob, David N Herndon, Hal K Hawkins, Perenlei Enkhbaatar, Robert A Cox
Respiratory tract infections and pneumonia are major causes of morbidity and mortality in burn victims, however, limited studies have examined the effects of burn injury on airway epithelium. The current study examines the effect of scald burn injury on rat tracheal epithelium at 5 days after injury and tests the hypothesis that treatment with febuxostat (FBX), an inhibitor of xanthine oxidase (XO), can be protective of cell homeostasis. Sprague Dawley rats were randomly divided into uninjured (sham), injured (control) and injured and FBX treated groups, n = 8...
2017: International Journal of Burns and Trauma
https://www.readbyqxmd.com/read/29118696/a-theory-of-how-columns-in-the-neocortex-enable-learning-the-structure-of-the-world
#19
Jeff Hawkins, Subutai Ahmad, Yuwei Cui
Neocortical regions are organized into columns and layers. Connections between layers run mostly perpendicular to the surface suggesting a columnar functional organization. Some layers have long-range excitatory lateral connections suggesting interactions between columns. Similar patterns of connectivity exist in all regions but their exact role remain a mystery. In this paper, we propose a network model composed of columns and layers that performs robust object learning and recognition. Each column integrates its changing input over time to learn complete predictive models of observed objects...
2017: Frontiers in Neural Circuits
https://www.readbyqxmd.com/read/29118112/the-biology-and-mathematical-modelling-of-glioma-invasion-a-review
#20
REVIEW
J C L Alfonso, K Talkenberger, M Seifert, B Klink, A Hawkins-Daarud, K R Swanson, H Hatzikirou, A Deutsch
Adult gliomas are aggressive brain tumours associated with low patient survival rates and limited life expectancy. The most important hallmark of this type of tumour is its invasive behaviour, characterized by a markedly phenotypic plasticity, infiltrative tumour morphologies and the ability of malignant progression from low- to high-grade tumour types. Indeed, the widespread infiltration of healthy brain tissue by glioma cells is largely responsible for poor prognosis and the difficulty of finding curative therapies...
November 2017: Journal of the Royal Society, Interface
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