keyword
MENU ▼
Read by QxMD icon Read
search

Mae

keyword
https://www.readbyqxmd.com/read/28212113/age-and-gender-dependency-of-physiological-networks-in-sleep
#1
Dagmar Krefting, Christoph Jansen, Thomas Penzel, Fang Han, Jan Kantelhardt
Recently, time delay stability analysis of biosignals has been successfully applied as a multivariate time series analysis method to assess the human physiological network in young adults. The degree of connectivity between different network nodes is described by the so-called link strength. Based on polysomnographic recordings (PSGs), it could be shown that the network changes with the sleep stage. Here, we apply the method to a large set of healthy controls spanning six decades of age. As it is well known, that the overall sleep architecture is dependent both on age and on gender, we particularly address the question, if these changes are also found in the network dynamics...
February 17, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28209292/cholesterol-screening-and-treatment-practices-and-preferences-a-survey-of-united-states-pediatricians
#2
Sarah D de Ferranti, Angie Mae Rodday, Susan K Parsons, William L Cull, Karen G O'Connor, Stephen R Daniels, Laurel K Leslie
OBJECTIVES: To determine pediatricians' practices, attitudes, and barriers regarding screening for and treatment of pediatric dyslipidemias in 9- to 11-year-olds and 17- to 21-year-olds. STUDY DESIGN: American Academy of Pediatrics (AAP) 2013-2014 Periodic Survey of a national, randomly selected sample of 1627 practicing AAP physicians. Pediatricians' responses were described and modeled. RESULTS: Of 614 (38%) respondents who met eligibility criteria, less than half (46%) were moderately/very knowledgeable about the 2008 AAP cholesterol statement; fewer were well-informed about 2011 National Heart, Lung, and Blood Institute Guidelines or 2007 US Preventive Service Task Force review (both 26%)...
February 13, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28208721/evolution-and-divergence-of-h3n8-equine-influenza-viruses-circulating-in-the-united-kingdom-from-2013-to-2015
#3
Adam Rash, Rachel Morton, Alana Woodward, Olivia Maes, John McCauley, Neil Bryant, Debra Elton
Equine influenza viruses (EIV) are a major cause of acute respiratory disease in horses worldwide and occasionally also affect vaccinated animals. Like other influenza A viruses, they undergo antigenic drift, highlighting the importance of both surveillance and virus characterisation in order for vaccine strains to be kept up to date. The aim of the work reported here was to monitor the genetic and antigenic changes occurring in EIV circulating in the UK from 2013 to 2015 and to identify any evidence of vaccine breakdown in the field...
February 8, 2017: Pathogens
https://www.readbyqxmd.com/read/28208719/micro-computed-tomography-detection-of-gold-nanoparticle-labelled-mesenchymal-stem-cells-in-the-rat-subretinal-layer
#4
Pooi Ling Mok, Sue Ngein Leow, Avin Ee-Hwan Koh, Hairul Harun Mohd Nizam, Suet Lee Shirley Ding, Chi Luu, Raduan Ruhaslizan, Hon Seng Wong, Wan Haslina Wan Abdul Halim, Min Hwei Ng, Ruszymah Binti Hj Idrus, Shiplu Roy Chowdhury, Catherine Mae-Lynn Bastion, Suresh Kumar Subbiah, Akon Higuchi, Abdullah A Alarfaj, Kong Yong Then
Mesenchymal stem cells are widely used in many pre-clinical and clinical settings. Despite advances in molecular technology; the migration and homing activities of these cells in in vivo systems are not well understood. Labelling mesenchymal stem cells with gold nanoparticles has no cytotoxic effect and may offer suitable indications for stem cell tracking. Here, we report a simple protocol to label mesenchymal stem cells using 80 nm gold nanoparticles. Once the cells and particles were incubated together for 24 h, the labelled products were injected into the rat subretinal layer...
February 8, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28208716/cell-imaging-counting-as-a-novel-ex-vivo-approach-for-investigating-drug-induced-hepatotoxicity-in-zebrafish-larvae
#5
Xuan-Bac Nguyen, Stanislav Kislyuk, Duc-Hung Pham, Angela Kecskés, Jan Maes, Deirdre Cabooter, Pieter Annaert, Peter De Witte, Annelii Ny
Drug-induced liver injury (DILI) is the most common reason for failures during the drug development process and for safety-related withdrawal of drugs from the pharmaceutical market. Therefore, having tools and techniques that can detect hepatotoxic properties in drug candidates at an early discovery stage is highly desirable. In this study, cell imaging counting was used to measure in a fast, straightforward, and unbiased way the effect of paracetamol and tetracycline, (compounds known to cause hepatotoxicity in humans) on the amount of DsRed-labeled hepatocytes recovered by protease digestion from Tg(fabp10a:DsRed) transgenic zebrafish...
February 8, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28201998/clinical-performance-evaluation-of-a-sensitive-rapid-low-throughput-test-for-kras-mutation-analysis-using-formalin-fixed-paraffin-embedded-tissue-samples
#6
Christine Weyn, Sofie Van Raemdonck, Robina Dendooven, Vincent Maes, Karen Zwaenepoel, Suzan Lambin, Patrick Pauwels
BACKGROUND: Testing for KRAS mutations in metastatic colorectal cancer (mCRC) on formalin-fixed, paraffin embedded (FFPE) tumor tissue has become standard of care. Different molecular methods exist to determine hotspot KRAS mutations in exon 2, 3 and 4, but testing is often limited by the sensitivity and the speed of analysis. The aim of this retrospective study was to establish the clinical performance of the Idylla™ KRAS Mutation Test on FFPE tumor samples of patients with mCRC. METHODS: KRAS mutation analysis was performed using the therascreen KRAS on the RotorGene Q platform (CE-IVD; Qiagen) and results were subsequently compared to the Idylla™ KRAS Mutation Test...
February 16, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28199413/low-prevalence-of-human-papillomavirus-in-head-and-neck-squamous-cell-carcinoma-in-the-northwest-region-of-the-philippines
#7
Pia Marie Albano, Dana Holzinger, Christianne Salvador, Jose Orosa, Sheryl Racelis, Modesty Leaño, Danilo Sanchez, Lara Mae Angeles, Gordana Halec, Markus Schmitt, John Donnie Ramos, Michael Pawlita
BACKGROUND: Geographic heterogeneity of human papillomavirus (HPV) involvement in head and neck squamous cell carcinoma (HNSCC) has been observed over the last few years. This trend has not been evaluated in the Philippines. Hence, this study aims to provide for the first time a data on the prevalence of HPV in HNSCC in the northwestern region of the Philippines. METHODS: Two hundred one (201) biopsy samples (179 formalin fixed paraffin embedded and 22 fresh frozen) from 163 Filipino HNSCC cases (oral cavity = 88; larynx = 60; oropharynx = 15) diagnosed between 2003 to 2013 were initially included in this study...
2017: PloS One
https://www.readbyqxmd.com/read/28197066/patch-based-super-resolution-of-mr-spectroscopic-images-application-to-multiple-sclerosis
#8
Saurabh Jain, Diana M Sima, Faezeh Sanaei Nezhad, Gilbert Hangel, Wolfgang Bogner, Stephen Williams, Sabine Van Huffel, Frederik Maes, Dirk Smeets
Purpose: Magnetic resonance spectroscopic imaging (MRSI) provides complementary information to conventional magnetic resonance imaging. Acquiring high resolution MRSI is time consuming and requires complex reconstruction techniques. Methods: In this paper, a patch-based super-resolution method is presented to increase the spatial resolution of metabolite maps computed from MRSI. The proposed method uses high resolution anatomical MR images (T1-weighted and Fluid-attenuated inversion recovery) to regularize the super-resolution process...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28196272/deep-sequencing-of-71-candidate-genes-to-characterize-variation-associated-with-alcohol-dependence
#9
Shaunna L Clark, Daniel E Adkins, Gaurav Kumar, Karolina A Aberg, Sri Nerella, Linying Xie, Ann L Collins, James J Crowley, Corey R Quackenbush, Christopher E Hilliard, Andrey A Shabalin, Scott I Vrieze, Roseann E Peterson, William E Copeland, Judy L Silberg, Matt McGue, Hermine Maes, William G Iacono, Patrick F Sullivan, Elizabeth J Costello, Edwin J van den Oord
BACKGROUND: Previous genome-wide association studies (GWASs) have identified a number of putative risk loci for alcohol dependence (AD). However, only a few loci have replicated and these replicated variants only explain a small proportion of AD risk. Using an innovative approach, the goal of this study was to generate hypotheses about potentially causal variants for AD that can be explored further through functional studies. METHODS: We employed targeted capture of 71 candidate loci and flanking regions followed by next-generation deep sequencing (mean coverage 78X) in 806 European Americans...
February 14, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28194268/filipino-women-s-diet-and-health-study-filwhel-design-and-methods
#10
Grace P Abris, Sangmo Hong, Sherlyn Mae P Provido, Jung Eun Lee, Chang Beom Lee
BACKGROUND: Immigration to South Korea from neighboring Asian countries has risen dramatically, primarily due to marriage between Korean men and foreign women. Although Filipino women rank fourth among married immigrant women, little is known about the health condition of this population. This manuscript focuses on the design and methods of Filipino women's diet and health study (FiLWHEL). SUBJECTS/METHODS: FiLWHEL is a cohort of Filipino women married to Korean men, aged 19 years old or over...
February 2017: Nutrition Research and Practice
https://www.readbyqxmd.com/read/28193309/sow-and-piglet-factors-determining-variation-of-colostrum-intake-between-and-within-litters
#11
I Declerck, S Sarrazin, J Dewulf, D Maes
Colostrum intake has a short- and long-term beneficial impact on piglet performance and mortality. Sows' colostrum production and piglets' colostrum intake are limited and highly variable. The present study investigated sow and piglet factors explaining the variation of colostrum intake between and within litters. The CV for colostrum intake and birth weight (BWb) of all piglets within a litter was calculated to evaluate the variation of colostrum intake and BWb within a litter (colostrum and litter BWb heterogeneity, respectively)...
February 14, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28192978/in-vitro-functional-quality-characterization-of-nota-modified-somatropins
#12
Nathalie Bracke, Han Yao, Evelien Wynendaele, Frederick Verbeke, Xiaolong Xu, Bert Gevaert, Alex Maes, Christophe Van de Wiele, Mike Sathekge, Sarah De Saeger, Bart M J De Spiegeleer
Chemical modifications on protein biopharmaceuticals introduce extra variability in addition to their inherent complexity, hence require more comprehensive analytical and functional characterization during their discovery, development and manufacturing. Somatropin (i.e. recombinant human growth hormone, rhGH) modified with the chelating agent S-2-(4-isothiocyanatobenzyl)-1,4,7-triazacyclononane-1,4,7-triacetic acid (p-SCN-Bn-NOTA) allows the incorporation of radiometals for research and possible theranostic purposes...
January 31, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28192624/mr-based-synthetic-ct-generation-using-a-deep-convolutional-neural-network-method
#13
Xiao Han
PURPOSE: Interests have been rapidly growing in the field of radiotherapy to replace CT with magnetic resonance imaging (MRI), due to superior soft tissue contrast offered by MRI and the desire to reduce unnecessary radiation dose. MR-only radiotherapy also simplifies clinical workflow and avoids uncertainties in aligning MR with CT. Methods, however, are needed to derive CT-equivalent representations, often known as synthetic CT (sCT), from patient MR images for the purpose of dose calculation and DRR-based patient positioning...
February 13, 2017: Medical Physics
https://www.readbyqxmd.com/read/28190490/risk-factors-for-development-of-lameness-in-gestating-sows-within-the-first-days-after-moving-to-group-housing
#14
Liesbet M Pluym, Dominiek Maes, Stephanie Van Weyenberg, Annelies Van Nuffel
Lameness in sows is an important welfare issue that is affected by housing conditions and is thought to be influenced by hierarchical fights within the first days after mixing sows in groups. A longitudinal study in 15 randomly selected herds was performed to investigate the incidence of sow lameness and possible risk factors within the first days of group housing. Each herd was visited just before and again 3-5 days after the sows were moved to group housing. The floor characteristics and dimensions of the group housing facilities were assessed...
February 2017: Veterinary Journal
https://www.readbyqxmd.com/read/28188888/two-hands-one-brain-and-aging
#15
REVIEW
Celine Maes, Jolien Gooijers, Jean-Jacques Orban de Xivry, Stephan P Swinnen, Matthieu P Boisgontier
Many activities of daily living require moving both hands in an organized manner in space and time. Therefore, understanding the impact of aging on bimanual coordination is essential for prolonging functional independence and well-being in older adults. Here we investigated the behavioral and neural determinants of bimanual coordination in aging. The studies surveyed in this review reveal that aging is associated with cortical hyper-activity (but also subcortical hypo-activity) during performance of bimanual tasks...
February 8, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28187767/erratum-to-effects-of-7%C3%A2-days-on-an-ad-libitum-low-fat-vegan-diet-the-mcdougall-program-cohort
#16
John McDougall, Laurie E Thomas, Craig McDougall, Gavin Moloney, Bradley Saul, John S Finnell, Kelly Richardson, Katelin Mae Petersen
No abstract text is available yet for this article.
February 10, 2017: Nutrition Journal
https://www.readbyqxmd.com/read/28187681/revision-and-cladistic-analysis-of-the-southeast-asian-leaf-dwelling-spider-genus-i-calapnita-i-simon-araneae-pholcidae
#17
Bernhard A Huber
The Southeast Asian pholcid genus Calapnita Simon, 1892 is revised, with descriptions of 17 new species, five of them in the phyllicola group (Borneo: C. lehi, C. kubah, C. bidayuh, C. bankirai; Malay Peninsula, Sumatra, Java: C. anai), 12 in the vermiformis group (Borneo: C. bario, C. bariengi, C. magaseng, C. dayak, C. lawangan, C. loksado; Sulawesi: C. bugis; Philippines: C. bohol, C. dinagat, C. mae, C. nunezae, C. maragusan). New records are listed for six of the eight previously described species. A morphological cladistic analysis supports the monophyly of Calapnita and of its two previously proposed species groups and presents several new phylogenetically informative characters...
January 13, 2017: Zootaxa
https://www.readbyqxmd.com/read/28185345/the-female-reproduction-and-senescence-nexus
#18
Cielo Mae D Marquez, Joyce A Ibana, Michael C Velarde
Successful pregnancy is regulated by several soluble factors that are differentially expressed throughout gestation. These factors are important to initiate and establish embryo implantation and parturition. Senescent cells, which undergo permanent cell proliferation arrest in response to stress, also produce several secreted factors, referred to as the senescence-associated secretory phenotype (SASP). Here, we review some of the secreted factors found during early and late pregnancy and compare their expression profile with those of the SASP...
February 10, 2017: American Journal of Reproductive Immunology: AJRI
https://www.readbyqxmd.com/read/28185203/hla-haploidentical-hematopoietic-cell-transplantation-using-clofarabine-and-busulfan-for-refractory-pediatric-hematological-malignancy
#19
Masatoshi Takagi, Yasuyoshi Ishiwata, Yuki Aoki, Satoshi Miyamoto, Akihiro Hoshino, Kazuaki Matsumoto, Akira Nishimura, Mari Tanaka, Masakatsu Yanagimachi, Noriko Mitsuiki, Kohsuke Imai, Hirokazu Kanegane, Michiko Kajiwara, Kanako Takikawa, Tsukasa Mae, Osamu Tomita, Junya Fujimura, Masato Yasuhara, Daisuke Tomizawa, Shuki Mizutani, Tomohiro Morio
Haploidentical hematopoietic cell transplantation (HCT) conditioning with clofarabine and target area under the blood concentration-time curve (AUC)-based busulfan adjustment was performed in three patients with refractory pediatric leukemia. The target AUC for two patients who had already received multiple transplantations was 3600 and 4000 μmol min/L, and that for the patient with Down's syndrome was 3000 μmol min/L. Regimen-related toxicity was well tolerated in all cases. All three maintained cytological remission throughout the follow-up period (between 31 and 167 weeks)...
February 9, 2017: International Journal of Hematology
https://www.readbyqxmd.com/read/28183566/relationship-between-normal-preoperative-white-blood-cell-count-and-major-adverse-events-after-endovascular-repair-for-abdominal-aortic-aneurysm-results-of-a-pilot-study
#20
Eleni Arnaoutoglou, George Kouvelos, Petros Tzimas, Eleni Laou, Vasilios Bouris, George Papadopoulos, Miltiadis Matsagkas
STUDY OBJECTIVE: To examine the association between preoperative white blood cell (WBC) count within the reference range and major adverse events (MAEs) following endovascular repair of abdominal aortic aneurysms (AAA). DESIGN: Prospective observational study. SETTING: Vascular surgery clinic in a tertiary university hospital. PATIENTS: One hundred fifty-three consecutive patients. INTERVENTION: Endovascular repair of AAA...
February 2017: Journal of Clinical Anesthesia
keyword
keyword
15124
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"