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Systematic review of ssi

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https://www.readbyqxmd.com/read/28723736/timing-of-preoperative-antibiotic-prophylaxis-in-54-552-patients-and-the-risk-of-surgical-site-infection-a-systematic-review-and-meta-analysis
#1
Stijn Willem de Jonge, Sarah L Gans, Jasper J Atema, Joseph S Solomkin, Patchen E Dellinger, Marja A Boermeester
The aim of the study was to assess the effect of timing of preoperative surgical antibiotic prophylaxis (SAP) on surgical site infection (SSI) and compare the different timing intervals.The benefit of routine use of SAP prior to surgery has long been recognized. However, the optimal timing has not been defined. For the purpose of developing recommendations for the World Health Organization guideline for SSI prevention, a systematic review and meta-analysis of all relevant evidence was conducted.Major medical databases were searched from 1990 to 2016...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28620749/bundles-prevent-surgical-site-infections-after-colorectal-surgery-meta-analysis-and-systematic-review
#2
Aleksander Zywot, Christine S M Lau, H Stephen Fletcher, Subroto Paul
INTRODUCTION: Colorectal surgeries (CRS) have one of the highest rates of surgical site infections (SSIs) with rates 15 to >30%. Prevention "bundles" or sets of evidence-based interventions are structured ways to improve patient outcomes. The aim sof this study is to evaluate CRS SSI prevention bundles, bundle components, and implementation and compliance strategies. METHODS: A meta-analysis of studies with pre- and post-implementation data was conducted to assess the impact of bundles on SSI rates (superficial, deep, and organ/space)...
June 15, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28557648/ventral-hernia-repair-a-meta-analysis-of-randomized-controlled-trials
#3
Julie L Holihan, Craig Hannon, Christopher Goodenough, Juan R Flores-Gonzalez, Kamal M Itani, Oscar Olavarria, Jiandi Mo, Tien C Ko, Lillian S Kao, Mike K Liang
BACKGROUND: From the patient's perspective, a ventral hernia (VH) can cause pain, adversely affect function, increase size, cosmetically distort the abdomen, and incarcerate/strangulate abdominal contents. The only known "cure" for a VH is surgical repair. The aim of this study was to review systematically the published randomized controlled trials (RCTs) of the surgical care of VH. METHOD: A search of the Ovid, MEDLINE, EMBASE, and Cochrane databases was performed to obtain reports of RCTs on the use of mesh reinforcement in abdominal wall hernia repair...
May 30, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28516472/nasal-decontamination-for-the-prevention-of-surgical-site-infection-in-staphylococcus-aureus-carriers
#4
REVIEW
Zhenmi Liu, Gill Norman, Zipporah Iheozor-Ejiofor, Jason Kf Wong, Emma J Crosbie, Peter Wilson
BACKGROUND: Surgical site infection rates in the month following surgery vary from 1% to 5%. Due to the large number of surgical procedures conducted annually, the costs of these surgical site infections (SSIs) can be considerable in financial and social terms. Nasal decontamination using antibiotics or antiseptics is performed to reduce the risk of SSIs by preventing organisms from the nasal cavity being transferred to the skin where a surgical incision will be made. Staphylococcus aureus (S aureus) colonises the nasal cavity and skin of carriers and can cause infection in open or unhealed surgical wounds...
May 18, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28484489/probiotics-reduce-postoperative-infections-in-patients-undergoing-colorectal-surgery-a-systematic-review-and-meta-analysis
#5
REVIEW
Peng Cheng Liu, Yu Ke Yan, Yu Jing Ma, Xiang Wen Wang, Jie Geng, Man Cai Wang, Feng Xian Wei, Ya Wu Zhang, Xiao Dong Xu, You Cheng Zhang
Background. We performed this meta-analysis to investigate the efficacy of probiotics on prevention of infection-related complications following colorectal resection. Method. PubMed, EMBASE, Cochrane Library, and the Web of Science were searched up to January 2016. According to the results, only randomized controlled trials that compared the efficacy of probiotics on patients with colorectal resection were included for meta-analysis. Results. Nine studies including a total of 1146 patients met the criteria (556 received multistrain probiotic bacteria, 590 with non-multistrain probiotic bacteria)...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28475793/effectiveness-of-probiotic-prebiotic-and-synbiotic-therapies-in-reducing-postoperative-complications-a-systematic-review-and-network-meta-analysis
#6
Nongyao Kasatpibal, JoAnne D Whitney, Surasak Saokaew, Kirati Kengkla, Margaret M Heitkemper, Anucha Apisarnthanarak
Background: Microbiome-directed therapies are increasingly used preoperatively and postoperatively to improve postoperative outcomes. Recently, the effectiveness of probiotics, prebiotics, and synbiotics in reducing postoperative complications (POCs) has been questioned. This systematic review aimed to examine and rank the effectiveness of these therapies on POCs in adult surgical patients. Methods: We searched for articles from PubMed, Embase, Cochrane, Web of Science, Scopus, and CINAHL plus...
May 15, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28467526/centers-for-disease-control-and-prevention-guideline-for-the-prevention-of-surgical-site-infection-2017
#7
Sandra I Berríos-Torres, Craig A Umscheid, Dale W Bratzler, Brian Leas, Erin C Stone, Rachel R Kelz, Caroline E Reinke, Sherry Morgan, Joseph S Solomkin, John E Mazuski, E Patchen Dellinger, Kamal M F Itani, Elie F Berbari, John Segreti, Javad Parvizi, Joan Blanchard, George Allen, Jan A J W Kluytmans, Rodney Donlan, William P Schecter
Importance: The human and financial costs of treating surgical site infections (SSIs) are increasing. The number of surgical procedures performed in the United States continues to rise, and surgical patients are initially seen with increasingly complex comorbidities. It is estimated that approximately half of SSIs are deemed preventable using evidence-based strategies. Objective: To provide new and updated evidence-based recommendations for the prevention of SSI...
May 3, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28461961/low-dose-dexamethasone-during-arthroplasty-what-do-we-know-about-the-risks
#8
Jessica T Wegener, Tim Kraal, Markus F Stevens, Markus W Hollmann, Gino M M J Kerkhoffs, Daniël Haverkamp
Dexamethasone is commonly applied during arthroplasty to control post-operative nausea and vomiting (PONV). However, conflicting views of orthopaedic surgeons and anaesthesiologists regarding the use of dexamethasone raise questions about risks of impaired wound healing and surgical site infections (SSI).The aim of this systematic review is to determine the level of evidence for the safety of a peri-operative single low dose of dexamethasone in hip and knee arthroplasty.We systematically reviewed literature in PubMed, EMBASE and Cochrane databases and cited references in articles found in the initial search from 1980 to 2013 based on predefined inclusion criteria...
August 2016: EFORT open reviews
https://www.readbyqxmd.com/read/28448203/systematic-review-and-meta-analysis-of-randomized-controlled-trials-evaluating-prophylactic-intra-operative-wound-irrigation-for-the-prevention-of-surgical-site-infections
#9
Stijn W de Jonge, Quirine J J Boldingh, Joseph S Solomkin, Benedetta Allegranzi, Matthias Egger, E Patchen Dellinger, Marja A Boermeester
BACKGROUND: Surgical site infections (SSIs) are one of the most common hospital-acquired infections. To reduce SSIs, prophylactic intra-operative wound irrigation (pIOWI) has been advocated, although the results to date are equivocal. To develop recommendations for the new World Health Organization (WHO) SSI prevention guidelines, a systematic literature review and a meta-analysis were conducted on the effectiveness of pIOWI using different agents as a means of reducing SSI. METHODS: The PUBMED, Embase, CENTRAL, CINAHL, and WHO databases were searched...
May 2017: Surgical Infections
https://www.readbyqxmd.com/read/28410761/impact-of-surgical-site-infection-on-healthcare-costs-and-patient-outcomes-a-systematic-review-in-six-european-countries
#10
REVIEW
J M Badia, A L Casey, N Petrosillo, P M Hudson, S A Mitchell, C Crosby
BACKGROUND: Surgical site infections (SSIs) are associated with increased morbidity and mortality. Furthermore, SSIs constitute a financial burden and negatively impact on patient quality of life (QoL). AIM: To assess, and evaluate the evidence for, the cost and health-related QoL (HRQoL) burden of SSIs across various surgical specialties in six European countries. METHODS: Electronic databases and conference proceedings were systematically searched to identify studies reporting the cost and HRQoL burden of SSIs...
May 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28402706/optimum-operating-room-environment-for-the-prevention-of-surgical-site-infections
#11
Sara Gaines, James N Luo, Jack Gilbert, Olga Zaborina, John C Alverdy
BACKGROUND: Surgical site infections (SSI), whether they be incisional or deep, can entail major morbidity and death to patients and additional cost to the healthcare system. A significant amount of effort has gone into optimizing the surgical patient and the operating room environment to reduce SSI. METHODS: Relevant guidelines and literature were reviewed. RESULTS: The modern practice of surgical antisepsis involves the employment of strict sterile techniques inside the operating room...
May 2017: Surgical Infections
https://www.readbyqxmd.com/read/28350942/prevention-of-surgical-site-infection-in-spine-surgery
#12
Paul A Anderson, Jason W Savage, Alexander R Vaccaro, Kristen Radcliff, Paul M Arnold, Brandon D Lawrence, Mohammed F Shamji
BACKGROUND: Spine surgery is complicated by an incidence of 1% to 9% of surgical site infection (SSI). The most common organisms are gram-positive bacteria and are endogenous, that is are brought to the hospital by the patient. Efforts to improve safety have been focused on reducing SSI using a bundle approach. The bundle approach applies many quality improvement efforts and has been shown to reduce SSI in other surgical procedures. OBJECTIVE: To provide a narrative review of practical solutions to reduce SSI in spine surgery...
March 1, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28277989/dialkylcarbamoyl-chloride-dacc-coated-dressings-in-the-management-and-prevention-of-wound-infection-a-systematic-review
#13
REVIEW
J P Totty, N Bua, G E Smith, A E Harwood, D Carradice, T Wallace, I C Chetter
OBJECTIVE: Dialkylcarbomoyl chloride (DACC)-coated dressings (Leukomed Sorbact and Cutimed Sorbact) irreversibly bind bacteria at the wound surface that are then removed when the dressing is changed. They are a recent addition to the wound care professional's armamentarium and have been used in a variety of acute and chronic wounds. This systematic review aims to assess the evidence supporting the use of DACC-coated dressings in the clinical environment. METHOD: We included all reports of the clinical use of DACC-coated dressings in relation to wound infection...
March 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28270910/american-society-for-enhanced-recovery-aser-and-perioperative-quality-initiative-poqi-joint-consensus-statement-on-prevention-of-postoperative-infection-within-an-enhanced-recovery-pathway-for-elective-colorectal-surgery
#14
Stefan D Holubar, Traci Hedrick, Ruchir Gupta, John Kellum, Mark Hamilton, Tong J Gan, Monty G Mythen, Andrew D Shaw, Timothy E Miller
BACKGROUND: Colorectal surgery (CRS) patients are an at-risk population who are particularly vulnerable to postoperative infectious complications. Infectious complications range from minor infections including simple cystitis and superficial wound infections to life-threatening situations such as lobar pneumonia or anastomotic leak with fecal peritonitis. Within an enhanced recovery pathway (ERP), there are multiple approaches that can be used to reduce the risk of postoperative infections...
2017: Perioperative Medicine
https://www.readbyqxmd.com/read/28264756/systematic-review-of-risk-prediction-scores-for-surgical-site-infection-or-periprosthetic-joint-infection-following-joint-arthroplasty
#15
REVIEW
S K Kunutsor, M R Whitehouse, A W Blom, A D Beswick
Accurate identification of individuals at high risk of surgical site infections (SSIs) or periprosthetic joint infections (PJIs) influences clinical decisions and development of preventive strategies. We aimed to determine progress in the development and validation of risk prediction models for SSI or PJI using a systematic review. We searched for studies that have developed or validated a risk prediction tool for SSI or PJI following joint replacement in MEDLINE, EMBASE, Web of Science and Cochrane databases; trial registers and reference lists of studies up to September 2016...
July 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28216243/effect-of-laminar-airflow-ventilation-on-surgical-site-infections-a-systematic-review-and-meta-analysis
#16
REVIEW
Peter Bischoff, N Zeynep Kubilay, Benedetta Allegranzi, Matthias Egger, Petra Gastmeier
BACKGROUND: The role of the operating room's ventilation system in the prevention of surgical site infections (SSIs) is widely discussed, and existing guidelines do not reflect current evidence. In this context, laminar airflow ventilation was compared with conventional ventilation to assess their effectiveness in reducing the risk of SSIs. METHODS: We searched MEDLINE, Embase, Cochrane Central Register of Controlled Trials, and WHO regional medical databases from Jan 1, 1990, to Jan 31, 2014...
May 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28124278/a-systematic-review-of-clinical-effectiveness-of-wound-edge-protector-devices-in-reducing-surgical-site-infections-in-patients-undergoing-abdominal-surgery
#17
REVIEW
Muhammad Shafique Sajid, M A Rathore, P Sains, K K Singh
This article highlights the clinical effectiveness of wound edge protector devices (WEPD) in preventing the post-operative surgical site infections (SSI) in patients undergoing abdominal surgery. Using the principles of meta-analysis and systematic review as recommended by the Cochrane Collaboration, the data from selected randomized, controlled trials (RCTs) were analysed to generate summated outcome and presented in the form of odds ratio (OR). Eighteen RCTs on 3808 reported the effectiveness of WEPD in patients undergoing abdominal surgery...
January 25, 2017: Updates in Surgery
https://www.readbyqxmd.com/read/28121042/economic-case-for-intraoperative-interventions-to-prevent-surgical-site-infection
#18
REVIEW
B M Gillespie, W Chaboyer, A Erichsen-Andersson, R M Hettiarachchi, S Kularatna
BACKGROUND: Surgical-site infection (SSI) occurs in 1-10 per cent of all patients undergoing surgery; rates can be higher depending on the type of surgery. The aim of this review was to establish whether (or not) surgical hand asepsis, intraoperative skin antisepsis and selected surgical dressings are cost-effective in SSI prevention, and to examine the quality of reporting. METHODS: The authors searched MEDLINE via Ovid, CINAHL via EBSCO, Cochrane Central and Scopus databases systematically from 1990 to 2016...
January 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28121028/network-meta-analysis-of-antibiotic-prophylaxis-for-prevention-of-surgical-site-infection-after-groin-hernia-surgery
#19
REVIEW
T Boonchan, C Wilasrusmee, M McEvoy, J Attia, A Thakkinstian
BACKGROUND: First-generation cephalosporins (such as cefazolin) are recommended as antibiotic prophylaxis in groin hernia repair, but other broad-spectrum antibiotics have also been prescribed in clinical practice. This was a systematic review and network meta-analysis to compare the efficacy of different antibiotic classes for prevention of surgical-site infection (SSI) after hernia repair. METHODS: RCTs were identified that compared efficacy of antibiotic prophylaxis on SSI after inguinal or femoral hernia repair from PubMed and Scopus databases up to March 2016...
January 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28109628/preoperative-bathing-of-the-surgical-site-with-chlorhexidine-for-infection-prevention-systematic-review-with-meta-analysis
#20
Lúcia Maciel de Castro Franco, Gláucia Fernandes Cota, Tatiana Saraiva Pinto, Flávia Falci Ercole
BACKGROUND: Preoperative bathing with 4% chlorhexidine is recommended as a measure to prevent surgical site infection (SSI) despite uncertainty regarding the effectiveness of the intervention. This review aimed to assess the effect of bathing with 4% chlorhexidine on the prevention of SSIs in clean surgeries compared with bathing with placebo solution or soap. METHODS: Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines for systematic reviews and the Cochrane manual were followed...
April 1, 2017: American Journal of Infection Control
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