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https://www.readbyqxmd.com/read/28521869/high-fgf21-levels-are-associated-with-altered-bone-homeostasis-in-hiv-1-infected-patients
#1
José M Gallego-Escuredo, Maria Karuna Lamarca, Joan Villarroya, Joan C Domingo, Ma Gracia Mateo, Ma Del Mar Gutierrez, Francesc Vidal, Francesc Villarroya, Pere Domingo, Marta Giralt
BACKGROUND: Fibroblast growth factor-21 (FGF21) has emerged as an important regulator of glucose, lipid, and body weight homeostasis. However, recent experimental studies have reported that increased FGF21 levels may lead to bone loss. OBJECTIVE: To assess the relationship of serum FGF21 levels and altered bone homeostasis in HIV-1-infected patients. DESIGN: Cross-sectional study of 137 HIV-1-infected patients and 35 healthy controls conducted at the Hospital de la Santa Creu i Sant Pau, Barcelona...
June 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/28513793/social-inequalities-in-the-prevalence-of-common-mental-disorders-in-adults-a-population-based-study-in-southern-brazil
#2
Ramona Sant'Ana Maggi de Moraes, Diego Augusto Santos Silva, Walter Ferreira de Oliveira, Marco Aurélio Peres
Objective: This study aimed to investigate the prevalence and factors associated with Common Mental Disorders (CMD) in adults in a capital city in Southern Brazil. Methods: Population-based survey conducted on 1,720 adults aged 20 - 59 years from Florianópolis, Southern Brazil. The CMD were investigated through the Self-Reporting Questionnaire (SRQ-20). The independent variables were demographic, socioeconomic, health-related behaviors, health conditions and use of health services...
January 2017: Revista Brasileira de Epidemiologia, Brazilian Journal of Epidemiology
https://www.readbyqxmd.com/read/28512370/occupational-contact-allergy-to-omeprazole-and-ranitidine
#3
Inmaculada Herrera-Mozo, Pere Sanz-Gallen, Gabriel Martí-Amengual
Omeprazole is a proton pump inhibition and ranitidine is an H2 histamine receptor antagonist widely used in the treatment of gastroesophageal reflex disease, peptic ulcer disease, Zollinger-Ellison syndrome and as a protector of the gastric mucosae. We report a case of occupational contact allergy to omeprazole and ranitidine. A 48-year-old man, with no pre-existing history of atopy or lifestyle factors. He neither had any medical history of consumption of drugs such as ranitidine and omeprazole. He worked for 19 months in the pharmaceutical company that manufactured ranitidine base...
May 16, 2017: Medycyna Pracy
https://www.readbyqxmd.com/read/28509420/the-magnitude-of-indigenous-and-non-indigenous-oral-health-inequalities-in-brazil-new-zealand-and-australia
#4
Helena S Schuch, Dandara G Haag, Kostas Kapellas, Rui Arantes, Marco A Peres, W M Thomson, Lisa M Jamieson
OBJECTIVE: To compare the magnitude of relative oral health inequalities between Indigenous and non-Indigenous persons from Brazil, New Zealand and Australia. METHODS: Data were from surveys in Brazil (2010), New Zealand (2009) and Australia (2004-06 and 2012). Participants were aged 35-44 years and 65-74 years. Indigenous and non-Indigenous inequalities were estimated by prevalence ratios (PR) and their corresponding 95% confidence intervals (CI), adjusting for sex, age and income...
May 16, 2017: Community Dentistry and Oral Epidemiology
https://www.readbyqxmd.com/read/28504741/real-time-acquisition-of-complex-optical-fields-by-binary-amplitude-modulation
#5
Eduardo Peters, Pere Clemente, E Salvador-Balaguer, Enrique Tajahuerce, Pedro Andrés, Darío G Pérez, Jesús Lancis
We describe, through simulations and experiments, a real-time wavefront acquisition technique using random binary amplitude masks and an iterative phase retrieval algorithm based on the Fresnel propagator. By using a digital micromirror device, it is possible to recover an unknown complex object by illuminating with this set of masks and simultaneously recording the resulting intensity patterns with a high-speed camera, making this technique suitable for dynamic applications.
May 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/28500551/effect-of-industrial-and-domestic-ash-from-biomass-combustion-and-spent-coffee-grounds-on-soil-fertility-and-plant-growth-experiments-at-field-conditions
#6
João Peres Ribeiro, Estela Domingos Vicente, Ana Paula Gomes, Maria Isabel Nunes, Célia Alves, Luís A C Tarelho
An experimental study was conducted at field conditions in order to evaluate the effect of application of ash from biomass combustion on some soil fertility characteristics and plant growth. Application of 7.5 Mg ha(-1) industrial fly ash (IA), domestic ash (DA), and a 50:50 mix of domestic ash (DA) and spent coffee grounds (SCG) was made in different soil parcels. Lolium perenne seeds were sown and the grown biomass was harvested and quantified after 60 days. Soil samples from each parcel were also collected after that period and characterized...
May 13, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28500294/adipocyte-fatty-acid-binding-protein-is-overexpressed-in-cirrhosis-and-correlates-with-clinical-outcomes
#7
Isabel Graupera, Mar Coll, Elisa Pose, Chiara Elia, Salvatore Piano, Elsa Solà, Delia Blaya, Patricia Huelin, Cristina Solé, Rebeca Moreira, Gloria de Prada, Núria Fabrellas, Adrià Juanola, Manuel Morales-Ruiz, Pau Sancho-Bru, Càndid Villanueva, Pere Ginès
Fatty-acid-binding proteins (FABPs) are small intracellular proteins that coordinate lipid-mediated processes by targeting metabolic and immune response pathways. The aim of the study was to investigate plasma FABPs levels and their relationship with clinical outcomes in cirrhosis. Plasma levels of L-FABP1(liver and kidney), I-FABP2(intestine), and A-FABP4(adipocyte and macrophages) were measured in 274 patients with decompensated cirrhosis. Hepatic gene expression of FABPs was assessed in liver biopsies from patients with decompensated cirrhosis and in liver cell types from mice with cirrhosis...
May 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28498797/natb-mediated-protein-n-%C3%AE-terminal-acetylation-is-a-potential-therapeutic-target-in-hepatocellular-carcinoma
#8
Leire Neri, Marta Lasa, Alberto Elosegui-Artola, Delia D'Avola, Beatriz Carte, Cristina Gazquez, Sara Alve, Pere Roca-Cusachs, Mercedes Iñarrairaegui, Jose Herrero, J Prieto, Bruno Sangro, Rafael Aldabe
The identification of new targets for systemic therapy of hepatocellular carcinoma (HCC) is an urgent medical need. Recently, we showed that hNatB catalyzes the N-α-terminal acetylation of 15% of the human proteome and that this action is necessary for proper actin cytoskeleton structure and function. In tumors, cytoskeletal changes influence motility, invasion, survival, cell growth and tumor progression, making the cytoskeleton a very attractive antitumor target. Here, we show that hNatB subunits are upregulated in in over 59% HCC tumors compared to non-tumor tissue and that this upregulation is associated with microscopic vascular invasion...
April 21, 2017: Oncotarget
https://www.readbyqxmd.com/read/28498502/real-time-three-dimensional-jaw-tracking-in-temporomandibular-disorders
#9
Danilo Vieira da Cunha, Viviane Veroni Degan, Mário Vedovello Filho, Douglas Peres Bellomo, Marlete Ribeiro Silva, Daniel Antônio Furtado, Adriano Oliveira Andrade, Selma Terezinha Milagre, Adriano Alves Pereira
When a dysfunction occurs in any component of the stomatognathic system, temporomandibular disorders (TMD) may originates. The aim of this study was to compare the deviations, displacement, and the execution speed of mandibular movements among asymptomatic participants and those with TMD. Convenience sampling was used; forty participants diagnosed by clinical evaluation following the Research Diagnostic Criteria for Temporomandibular Disorders were divided into three groups: Arthropathy (GART, 10 participants, 40% men), Myopathy (GMYO, 10 participants, 30% men), and the Control Group (CG, 20 asymptomatic-participants, 25% men)...
May 12, 2017: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/28497805/the-changing-prevalence-and-incidence-of-dementia-over-time-current-evidence
#10
REVIEW
Yu-Tzu Wu, Alexa S Beiser, Monique M B Breteler, Laura Fratiglioni, Catherine Helmer, Hugh C Hendrie, Hiroyuki Honda, M Arfan Ikram, Kenneth M Langa, Antonio Lobo, Fiona E Matthews, Tomoyuki Ohara, Karine Pérès, Chengxuan Qiu, Sudha Seshadri, Britt-Marie Sjölund, Ingmar Skoog, Carol Brayne
Dementia is an increasing focus for policymakers, civil organizations and multidisciplinary researchers. The most recent descriptive epidemiological research into dementia is enabling investigation into how the prevalence and incidence are changing over time. To establish clear trends, such comparisons need to be founded on population-based studies that use similar diagnostic and research methods consistently over time. This narrative Review synthesizes the findings from 14 studies that investigated trends in dementia prevalence (nine studies) and incidence (five studies) from Sweden, Spain, the UK, the Netherlands, France, the USA, Japan and Nigeria...
May 12, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28493998/metabolomics-analysis-finding-out-metabolic-building-blocks
#11
Ricardo Alberich, José A Castro, Mercè Llabrés, Pere Palmer-Rodríguez
In this paper we propose a new methodology for the analysis of metabolic networks. We use the notion of strongly connected components of a graph, called in this context metabolic building blocks. Every strongly connected component is contracted to a single node in such a way that the resulting graph is a directed acyclic graph, called a metabolic DAG, with a considerably reduced number of nodes. The property of being a directed acyclic graph brings out a background graph topology that reveals the connectivity of the metabolic network, as well as bridges, isolated nodes and cut nodes...
2017: PloS One
https://www.readbyqxmd.com/read/28492813/patient-safety-in-the-care-of-hospitalised-children-evidence-for-paediatric-nursing
#12
Wiliam Wegner, Manuela Usevicius Maia da Silva, Merianny de Avila Peres, Larissa Edom Bandeira, Elemara Frantz, Daisy Zanchi de Abreu Botene, Caroline Maier Predebon
Objectives: To describe evidence of international literature on the safe care of the hospitalised child after the World Alliance for Patient Safety and list contributions of the general theoretical framework of patient safety for paediatric nursing. Method: An integrative literature review between 2004 and 2015 using the databases PubMed, Cumulative Index of Nursing and Allied Health Literature (CINAHL), Scopus, Web of Science and Wiley Online Library, and the descriptors Safety or Patient safety, Hospitalised child, Paediatric nursing, and Nursing care...
May 4, 2017: Revista Gaúcha de Enfermagem
https://www.readbyqxmd.com/read/28491945/reference-values-for-t-b-and-nk-human-lymphocyte-subpopulations-in-adults
#13
P A Apoil, B Puissant-Lubrano, N Congy-Jolivet, M Peres, J Tkaczuk, F Roubinet, A Blancher
The data presented in this paper are reference ranges for frequencies of thirty-eight subpopulations of T, B and NK lymphocytes, established from a cohort of 253 healthy blood donors aged from 19 to 67. When relevant, the influence of age or sex was taken into account to calculate these reference values. This article is related to the research article entitled "Influence of age, sex and HCMV-serostatus on blood lymphocyte subpopulations in healthy adults" (Apoil et al., 2017) [1]. Immunophenotyping data obtained from each individual is made publicly available for extended analyses...
June 2017: Data in Brief
https://www.readbyqxmd.com/read/28489800/characteristics-and-outcome-of-spontaneous-bacterial-meningitis-in-patients-with-cancer-compared-to-patients-without-cancer
#14
Virginia Pomar, Natividad Benito, Joaquin López-Contreras, Pere Coll, Mercedes Gurguí, Pere Domingo
In cancer patients, who are frequently immunocompromised, bacterial meningitis (BM) can be a severe complication, with a different presentation, etiology, and course, compared to patients without cancer. Our objective is to compare the characteristics and outcomes of BM in patients with and without cancer. A single-center, prospective observational cohort study, conducted between 1982 and 2012, in a tertiary university hospital in Barcelona (Spain). The main outcome measure is in-hospital mortality. We evaluated 659 episodes of BM; 97 (15%) had active cancer...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28487225/structural-and-functional-alterations-associated-with-deutan-n94k-and-r330q-mutations-of-green-cone-opsin
#15
Sundaramoorthy Srinivasan, Miguel A Fernández-Sampedro, Eva Ramon, Pere Garriga
Deuteranopia is an X-linked congenital dichromatic condition in which single point mutations in green cone opsin lead to defective non-functional cone photoreceptor cells. Green cone opsin belongs to the G protein-coupled receptor superfamily and consists of a seven transmembrane helical apoprotein covalently bound to 11-cis-retinal, by means of a protonated Schiff base linkage, in its inactive dark state. Several point mutations in green cone opsin have been reported to cause deuteranopia, but the structural details underlying the molecular mechanisms behind the malfunction of mutated opsins have not been clearly established...
May 6, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28484913/tooth-loss-and-general-quality-of-life-in-dentate-adults-from-southern-brazil
#16
Dandara Gabriela Haag, Karen Glazer Peres, David Simon Brennan
PURPOSE: This study aimed to estimate the association between the number of teeth and general quality of life in adults. METHODS: A population-based study was conducted with 1720 individuals aged 20-59 years residing in Florianópolis, Brazil, in 2009. Data were collected at participants' households using a structured questionnaire. In 2012, a second wave was undertaken with 1222 individuals. Oral examinations were performed for number of teeth, prevalence of functional dentition (≥21 natural teeth), and shortened dental arch (SDA), which were considered the main exposures...
May 8, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28483052/loss-of-type-iv-glandular-trichomes-is-a-heterochronic-trait-in-tomato-and-can-be-reverted-by-promoting-juvenility
#17
Eloisa Vendemiatti, Agustin Zsögön, Geraldo Felipe Ferreira E Silva, Frederico Almeida de Jesus, Lucas Cutri, Cassia Regina Fernandes Figueiredo, Francisco André Ossamu Tanaka, Fábio Tebaldi Silveira Nogueira, Lázaro Eustáquio Pereira Peres
Glandular trichomes are structures with widespread distribution and deep ecological significance. In the Solanum genus, type-IV glandular trichomes provide resistance to insect pests. The occurrence of these structures is, however, poorly described and controversial in cultivated tomato (Solanum lycopersicum). Optical and scanning electron microscopy were used to screen a series of well-known commercial tomato cultivars, revealing the presence of type-IV trichomes on embryonic (cotyledons) and juvenile leaves...
June 2017: Plant Science: An International Journal of Experimental Plant Biology
https://www.readbyqxmd.com/read/28479340/pericytes-are-heterogeneous-in-their-origin-within-the-same-tissue
#18
Pedro Henrique Dias Moura Prazeres, Isadora Fernandes Gilson Sena, Isabella da Terra Borges, Patrick Orestes de Azevedo, Julia Peres Andreotti, Ana Emília de Paiva, Viviani Mendes de Almeida, Daniel Arthur de Paula Guerra, Gabryella Soares Pinheiro Dos Santos, Akiva Mintz, Osvaldo Delbono, Alexander Birbrair
Pericytes heterogeneity is based on their morphology, distribution, and markers. It is well known that pericytes from different organs may have distinct embryonic sources. Yamazaki et al. (2017) using several transgenic mouse model reveal by cell-lineage tracing that pericytes are even more heterogeneous than previously appreciated. This study shows that pericytes from within the same tissue may be heterogeneous in their origin. Remarkably, a subpopulation of embryonic dermal pericytes derives from the hematopoietic lineage, an unexpected source...
May 4, 2017: Developmental Biology
https://www.readbyqxmd.com/read/28477392/validity-of-different-tools-to-assess-sleep-bruxism-a-meta-analysis
#19
REVIEW
Elora Casett, Jéssica C Réus, Juliana Stuginski-Barbosa, André L Porporatti, Maria C Carra, Marco A Peres, Graziela De L Canto, Daniele Manfredini
This systematic review and meta-analysis (MA) aimed to evaluate the diagnostic validity of questionnaires, clinical assessment, and portable diagnostic devices compared to the reference standard method polysomnography (PSG) in assessing sleep bruxism (SB). Two reviewers searched electronic databases for diagnostic test accuracy studies that compared questionnaires, clinical assessment or portable diagnostic devices for SB, with the reference standard method PSG, comprising previous studies from all languages and with no restrictions regarding age, gender or time of publication...
May 6, 2017: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/28475487/can-somatosensory-electrical-stimulation-relieve-spasticity-in-post-stroke-patients-a-tms-pilot-study
#20
André Salles Cunha Peres, Victor Hugo Souza, João Marcos Yamasaki Catunda, Kelley Cristine Mazzeto-Betti, Taiza Elaine Grespan Santos-Pontelli, Claudia Domingues Vargas, Oswaldo Baffa, Draulio Barros de Araújo, Octávio Marques Pontes-Neto, João Pereira Leite, Marco Antonio Cavalcanti Garcia
Evidence suggests that somatosensory electrical stimulation (SES) may decrease the degree of spasticity from neural drives, although there is no agreement between corticospinal modulation and the level of spasticity. Thus, stroke patients and healthy subjects were submitted to SES (3 Hz) for 30' on the impaired and dominant forearms, respectively. Motor evoked potentials induced by single-pulse transcranial magnetic stimulation were collected from two forearm muscles before and after SES. The passive resistance of the wrist joint was measured with an isokinetic system...
May 5, 2017: Biomedizinische Technik. Biomedical Engineering
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