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https://www.readbyqxmd.com/read/28803372/oxidation-of-winery-wastewater-by-sulphate-radicals-catalytic-and-solar-photocatalytic-activations
#1
Jorge Rodríguez-Chueca, Carlos Amor, Joana Mota, Marco S Lucas, José A Peres
The treatment of winery effluents through sulphate radical-based advanced oxidation processes (SR-AOPs) driven by solar radiation is reported in this study. Photolytic and catalytic activations of peroxymonosulphate (PMS) and persulphate (KPS and SPS) at different pH values (4.5 and 7) were studied in the degradation of organic matter. Portugal is one of the largest wine producers in Europe. The wine making activities generate huge volume of effluents characterized by a variable volume and organic load, being their seasonal nature one of the most important drawbacks...
August 12, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28803203/use-of-bias-correction-techniques-to-improve-seasonal-forecasts-for-reservoirs-a-case-study-in-northwestern-mediterranean
#2
Raül Marcos, Ma Carmen Llasat, Pere Quintana-Seguí, Marco Turco
In this paper, we have compared different bias correction methodologies to assess whether they could be advantageous for improving the performance of a seasonal prediction model for volume anomalies in the Boadella reservoir (northwestern Mediterranean). The bias correction adjustments have been applied on precipitation and temperature from the European Centre for Middle-range Weather Forecasting System 4 (S4). We have used three bias correction strategies: two linear (mean bias correction, BC, and linear regression, LR) and one non-linear (Model Output Statistics analogs, MOS-analog)...
August 9, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28798491/phytochromobilin-deficiency-impairs-sugar-metabolism-through-the-regulation-of-cytokinin-and-auxin-signaling-in-tomato-fruits
#3
Ricardo Ernesto Bianchetti, Aline Bertinatto Cruz, Bruna Soares Oliveira, Diego Demarco, Eduardo Purgatto, Lázaro Eustáquio Pereira Peres, Magdalena Rossi, Luciano Freschi
Phytochomes and plant hormones have been emerging as important regulators of fleshy fruit biology and quality traits; however, the relevance of phytochrome-hormonal signaling crosstalk in controlling fruit development and metabolism remains elusive. Here, we show that the deficiency in phytochrome chromophore phytochromobilin (PΦB) biosynthesis inhibits sugar accumulation in tomato (Solanum lycopersicum) fruits by transcriptionally downregulating sink- and starch biosynthesis-related enzymes, such as cell-wall invertases, sucrose transporters and ADP-glucose pyrophosphorylases...
August 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28797743/importance-of-a-5-versus-7-day-pill-free-interval-in-a-gnrh-antagonist-protocol-using-corifollitropin-alfa-a-prospective-cohort-study-in-oocyte-donors
#4
Alicia Pérez-Calvo, Francisca Martínez, Christophe Blockeel, Elisabeth Clúa, Ignacio Rodríguez, Pere N Barri, Buenaventura Coroleu
In this prospective cohort study, oocyte donors were recruited prospectively and assigned to receive corifollitropin alfa: 5 days after pill discontinuation (group D5; 42 donors), or 7 days after pill discontinuation (group D7; 50 donors) in a gonadotrophin-releasing hormone antagonist protocol. Fixed additional daily doses of 200 IU recombinent FSH (rFSH) were started after 7 days of corifollitropinalfa, until triggering. No significant differences in basal characteristics were observed between both groups...
July 14, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28797327/outbreak-of-intestinal-amoebiasis-among-men-who-have-sex-with-men-barcelona-spain-october-2016-and-january-2017
#5
Laura Escolà-Vergé, Maider Arando, Martí Vall, Roger Rovira, Mateu Espasa, Elena Sulleiro, Pere Armengol, Francesc Zarzuela, María-Jesús Barberá
Entamoeba histolytica has been recently recognised as an emerging sexually transmissible pathogen in men who have sex with men (MSM), causing sporadic outbreaks in countries where it is not endemic. Here we report two closed clusters of invasive amoebiasis occurring in Barcelona, Spain, in October 2016 (four cases) and in January 2017 (four cases).
July 27, 2017: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/28796636/effect-of-tms-coil-orientation-on-the-spatial-distribution-of-motor-evoked-potentials-in-an-intrinsic-hand-muscle
#6
Victor Hugo Souza, Taian Martins Vieira, André Salles Cunha Peres, Marco Antonio Cavalcanti Garcia, Claudia Domingues Vargas, Oswaldo Baffa
Previous reports on the relationship between coil orientation and amplitude of motor evoked potential (MEP) in transcranial magnetic stimulation (TMS) did not consider the effect of electrode arrangement. Here we explore this open issue by investigating whether TMS coil orientation affects the amplitude distribution of MEPs recorded from the abductor pollicis brevis (APB) muscle with a bi-dimensional grid of 61 electrodes. Moreover, we test whether conventional mono- and bipolar montages provide representative MEPs compared to those from the grid of electrodes...
August 10, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/28783691/characterization-of-t-and-b-cell-repertoire-diversity-in-patients-with-rag-deficiency
#7
Yu Nee Lee, Francesco Frugoni, Kerry Dobbs, Irit Tirosh, Likun Du, Francesca A Ververs, Heng Ru, Lisa Ott de Bruin, Mehdi Adeli, Jacob H Bleesing, David Buchbinder, Manish J Butte, Caterina Cancrini, Karin Chen, Sharon Choo, Reem A Elfeky, Andrea Finocchi, Ramsay L Fuleihan, Andrew R Gennery, Dalia H El-Ghoneimy, Lauren A Henderson, Waleed Al-Herz, Elham Hossny, Robert P Nelson, Sung-Yun Pai, Niraj C Patel, Shereen M Reda, Pere Soler-Palacin, Raz Somech, Paolo Palma, Hao Wu, Silvia Giliani, Jolan E Walter, Luigi D Notarangelo
Recombination-activating genes 1 and 2 (RAG1 and RAG2) play a critical role in T and B cell development by initiating the recombination process that controls the expression of T cell receptor (TCR) and immunoglobulin genes. Mutations in the RAG1 and RAG2 genes in humans cause a broad spectrum of phenotypes, including severe combined immunodeficiency (SCID) with lack of T and B cells, Omenn syndrome, leaky SCID, and combined immunodeficiency with granulomas or autoimmunity (CID-G/AI). Using next-generation sequencing, we analyzed the TCR and B cell receptor (BCR) repertoire in 12 patients with RAG mutations presenting with Omenn syndrome (n = 5), leaky SCID (n = 3), or CID-G/AI (n = 4)...
December 16, 2016: Science Immunology
https://www.readbyqxmd.com/read/28781784/prevalence-of-silent-breast-cancer-in-autopsy-specimens-as-studied-by-the-disease-being-held-by-image-guided-biopsies-the-pilot-study-and-literature-review
#8
Zacharoula Sidiropoulou, Ana Paula Vasconcelos, Cristiana Couceiro, Carlos Dos Santos, Ana Virginia Araújo, Inês Alegre, Claudia Santos, Filipa Costa, Vanessa Henriques, Carlos Neves, Fátima Cardoso, Pere Gascon
Breast cancer epidemiological patterns vary in European countries, which present different incidence rates. Data have suggested that the reduction in breast cancer mortality is not only due to the early detection of the disease, but is, in almost equal part, due to screening and to the advances that have been made in molecular medicine and the development of novel therapies. The aim of the present study is to quantify the actual number of cases of breast cancer present in both of the sexes by calculating the prevalence of silent breast cancer in corpses...
August 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28772630/inducing-stable-%C3%AE-%C3%AE-microstructures-during-selective-laser-melting-of-ti-6al-4v-using-intensified-intrinsic-heat-treatments
#9
Pere Barriobero-Vila, Joachim Gussone, Jan Haubrich, Stefanie Sandlöbes, Julio Cesar Da Silva, Peter Cloetens, Norbert Schell, Guillermo Requena
Selective laser melting is a promising powder-bed-based additive manufacturing technique for titanium alloys: near net-shaped metallic components can be produced with high resource-efficiency and cost savings [...].
March 7, 2017: Materials
https://www.readbyqxmd.com/read/28772486/study-of-the-molecular-dynamics-of-multiarm-star-polymers-with-a-poly-ethyleneimine-core-and-poly-lactide-multiarms
#10
Frida Román, Pere Colomer, Yolanda Calventus, John M Hutchinson
Multiarm star polymers, denoted PEIx-PLAy and containing a hyperbranched poly(ethyleneimine) (PEI) core of different molecular weights x and poly(lactide) (PLA) arms with y ratio of lactide repeat units to N links were used in this work. Samples were preconditioned to remove the moisture content and then characterized by thermogravimetric analysis (TGA), differential scanning calorimetry (DSC) and dielectric relaxation spectroscopy (DRS). The glass transition temperature, Tg, is between 48 and 50 °C for all the PEIx-PLAy samples...
February 4, 2017: Materials
https://www.readbyqxmd.com/read/28770413/escherichia-coli-early-onset-sepsis-trends-over-two-decades
#11
Natalia Mendoza-Palomar, Milena Balasch-Carulla, Sabina González-Di Lauro, Maria Concepció Céspedes, Antònia Andreu, Marie Antoinette Frick, Maria Ángeles Linde, Pere Soler-Palacin
Escherichia coli early-onset sepsis (EOS) is an important cause of mortality and morbidity in neonates, especially in preterm and very low birth weight (VLBW) newborns. The aim of our study was to evaluate potential changes in the clinical and microbiological characteristics of E. coli EOS in our setting. Epidemiological, clinical, and microbiological data from all neonates with proven E. coli EOS from January 1994 to December 2014 were retrospectively collected in a single tertiary care hospital in Barcelona (Spain)...
August 2, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28769900/intrinsic-and-extrinsic-aspects-on-campylobacter-jejuni-biofilms
#12
Roberta T Melo, Eliane P Mendonça, Guilherme P Monteiro, Mariana C Siqueira, Clara B Pereira, Phelipe A B M Peres, Heriberto Fernandez, Daise A Rossi
Biofilm represents a way of life that allows greater survival of microorganisms in hostile habitats. Campylobacter jejuni is able to form biofilms in vitro and on surfaces at several points in the poultry production chain. Genetic determinants related to their formation are expressed differently between strains and external conditions are decisive in this respect. Our approach combines phylogenetic analysis and the presence of seven specific genes linked to biofilm formation in association with traditional microbiology techniques, using Mueller Hinton and chicken juice as substrates in order to quantify, classify, determine the composition and morphology of the biomass of simple and mixed biofilms of 30 C...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28767915/evaluation-of-periodontal-condition-and-risk-in-patients-with-chronic-kidney-disease-on-hemodialysis
#13
Yeon Jung Kim, Luciana Martins de Moura, Christiane Peres Caldas, Caroline Perozini, Gilson Fernandes Ruivo, Debora Pallos
Objective: To establish a profile of periodontal conditions in chronic kidney disease patients on hemodialysis and their periodontal risk. Methods: We included 115 patients on hemodialysis. Clinical periodontal parameters assessed were: plaque index, gingival index, probing depth and clinical attachment level. Patients were classified according to presence/absence and severity of periodontal disease and periodontal risk. Results: In 107 dentate patients (93%) the plaque index was 1...
April 2017: Einstein
https://www.readbyqxmd.com/read/28765084/surveillance-of-high-grade-cervical-cancer-precursors-cin-iii-ais-in-four-population-based-cancer-registries-united-states-2009-2012
#14
Meg Watson, Ashwini Soman, Elaine W Flagg, Elizabeth Unger, Dennis Deapen, Vivien W Chen, Lauren C Peres, Glenn Copeland, Thomas C Tucker, Erin Garnett, Mona Saraiya
Surveillance of cervical intraepithelial neoplasia grade III (CIN III) and adenocarcinoma in situ (AIS) is important for determining the burden of a preventable disease, identifying effects of vaccination on future diagnoses, and developing targeted programs. We analyzed population-based rates of high-grade cervical cancer precursor lesions using data from four central cancer registries (diagnosis years 2009-2012 from Louisiana, Kentucky, Michigan, and diagnosis years 2011-2012 from Los Angeles) by age, race, and histology...
July 29, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28764747/dengue-specific-serotype-related-to-clinical-severity-during-the-2012-2013-epidemic-in-centre-of-brazil
#15
Benigno A M Rocha, Adriana O Guilarde, Angela F L T Argolo, Marianna Peres Tassara, Lucimeire A da Silveira, Isabela C Junqueira, Marília D Turchi, Valéria C R Féres, Celina M T Martelli
Please see Additional file 1 for translations of the abstract into the five official working languages of the United Nations. BACKGROUND: Currently, in Brazil, there is a co-circulation of the four dengue (DENV-1 to DENV-4) serotypes. This study aimed to assess whether different serotypes and antibody response patterns were associated with the severity of the disease during a dengue outbreak, which occurred in 2012/2013 in centre of Brazil. METHODS: We conducted a prospective study with 452 patients with laboratory confirmed dengue in central Brazil, from January 2012 to July 2013...
August 2, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28759394/impact-of-prolonged-breastfeeding-on-dental-caries-a-population-based-birth-cohort-study
#16
Karen Glazer Peres, Gustavo G Nascimento, Marco Aurelio Peres, Murthy N Mittinty, Flavio Fernando Demarco, Ina Silva Santos, Alicia Matijasevich, Aluisio J D Barros
BACKGROUND: Few studies have assessed the effect of breastfeeding, bottle feeding, and sugar consumption on children's dental caries. We investigated whether the duration of breastfeeding is a risk factor for dental caries in the primary dentition, independently of sugar consumption. METHODS: An oral health study (n = 1303) nested in a birth cohort study was carried out in southern Brazil. The average number of decayed, missing, and filled primary tooth surfaces (dmfs) and severe early childhood caries (S-ECC: dmfs ≥6) were investigated at age 5 years...
July 2017: Pediatrics
https://www.readbyqxmd.com/read/28757416/the-tumour-suppressor-mir-137-inhibits-malignant-melanoma-migration-by-targetting-the-tbx3-transcription-factor
#17
Jade Peres, Eliza M Kwesi-Maliepaard, Florian Rambow, Lionel Larue, Sharon Prince
The transcription factor, TBX3, is a key driver of malignant melanoma and any drug that impacts its expression is likely to have an impact on the treatment of this highly aggressive and treatment resistant cancer. Replacement of miRNAs that target oncogenes has gained much attention as a therapy because it is anticipated to be effective with little side-effects since miRNAs are naturally occurring and often target large set of genes in the same oncogenic pathway. Here we show that miR-137 levels correlate inversely with TBX3 mRNA levels in a panel of melanoma cell lines and in a cohort of patients with primary melanoma...
July 28, 2017: Cancer Letters
https://www.readbyqxmd.com/read/28757264/baseline-parameters-in-clinical-trials-for-nonalcoholic-steatohepatitis-recommendations-from-the-liver-forum
#18
EDITORIAL
Yuval A Patel, Joanne Imperial, Andrew J Muir, Quentin M Anstee, David DeBrota, Lara Dimick-Santos, Claudia Filozof, Ruby Mehta, Arun Sanyal, Elmer Schabel, Brent A Neuschwander-Tetri, Veronica Miller
No abstract text is available yet for this article.
July 27, 2017: Gastroenterology
https://www.readbyqxmd.com/read/28753979/lack-of-association-between-hepatitis-c-virus-core-gene-variation-70-91aa-and-insulin-resistance
#19
Letícia de Paula Scalioni, Allan Peres da Silva, Juliana Custódio Miguel, Márcia Paschoal do Espírito Santo, Vanessa Alves Marques, Carlos Eduardo Brandão-Mello, Cristiane Alves Villela-Nogueira, Lia Laura Lewis-Ximenez, Elisabeth Lampe, Livia Melo Villar
The role of hepatitis C virus (HCV) in insulin resistance (IR) is not fully understood. The aim of this study was to determine the impact of amino acid (aa) substitutions in the core region of HCV according to IR and to identify clinical and laboratory associations. Ninety-two treatment-naive HCV patients were recruited to determine laboratory data and blood cell count. IR was determined using Homeostasis Model Assessment (HOMA) index where IR was defined as HOMA ≥2. HCV RNA load and genotype were determined by Abbott Real time HCV...
July 21, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28751691/a-deletion-affecting-an-lrr-rlk-gene-co-segregates-with-the-fruit-flat-shape-trait-in-peach
#20
Elena López-Girona, Yu Zhang, Iban Eduardo, José Ramón Hernández Mora, Konstantinos G Alexiou, Pere Arús, María José Aranzana
In peach, the flat phenotype is caused by a partially dominant allele in heterozygosis (Ss), fruits from homozygous trees (SS) abort a few weeks after fruit setting. Previous research has identified a SSR marker (UDP98-412) highly associated with the trait, found suitable for marker assisted selection (MAS). Here we report a ∼10 Kb deletion affecting the gene PRUPE.6G281100, 400 Kb upstream of UDP98-412, co-segregating with the trait. This gene is a leucine-rich repeat receptor-like kinase (LRR-RLK) orthologous to the Brassinosteroid insensitive 1-associated receptor kinase 1 (BAK1) group...
July 27, 2017: Scientific Reports
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