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https://www.readbyqxmd.com/read/28821108/modified-bacterial-cellulose-based-self-healable-polyeloctrolyte-film-for-wound-dressing-application
#1
Moumita Khamrai, Sovan Lal Banerjee, Patit P Kundu
In this investigation, we prepare a self-healable polyelectrolyte film via crosslinking the cationically charged chitosan (Cts) with anionically modified bacterial cellulose (BC), which is a green source of nano-filler. This polyelectrolyte film is able to show dynamic self-healing activity at physiological pH condition via adapting ionic interaction, a state of non-covalent bond. BC was prepared using Glucanoacetobacter xylinus (MTCC7795) bacteria and after that its surface was modified with anionic poly(acrylic acid) using "grafting from" technique...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28819314/a-symbiotic-like-biologically-driven-regenerating-fabric
#2
Neta Raab, Joe Davis, Rachel Spokoini-Stern, Moran Kopel, Ehud Banin, Ido Bachelet
Living organisms constantly maintain their structural and biochemical integrity by the critical means of response, healing, and regeneration. Inanimate objects, on the other hand, are axiomatically considered incapable of responding to damage and healing it, leading to the profound negative environmental impact of their continuous manufacturing and trashing. Objects with such biological properties would be a significant step towards sustainable technology. In this work we present a feasible strategy for driving regeneration in fabric by means of integration with a bacterial biofilm to obtain a symbiotic-like hybrid - the fabric provides structural framework to the biofilm and supports its growth, whereas the biofilm responds to mechanical tear by synthesizing a silk protein engineered to self-assemble upon secretion from the cells...
August 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28818631/topical-medical-cannabis-tmc-a-new-treatment-for-wound-pain-three-cases-of-pyoderma-gangrenosum
#3
Vincent Maida, Jason Corban
Pain associated with integumentary wounds is highly prevalent yet it remains an area of significant unmet need within healthcare. Currently, systemically administered opioids are the mainstay of treatment. However, recent publications are casting opioids in a negative light given their high side effect profile, inhibition of wound healing, and association with accidental overdose, incidents that are frequently fatal. Thus, novel analgesic strategies for wound-related pain need to be investigated. The ideal methods of pain relief for wound patients are modalities that are topical, lack systemic side effects, non-invasive, self-administered, and display rapid onset of analgesia...
August 14, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28816490/evaluation-of-the-effects-of-receiving-trauma-informed-practices-on-domestic-violence-shelter-residents
#4
Cris M Sullivan, Lisa A Goodman, Tyler Virden, Jennifer Strom, Rachel Ramirez
Domestic violence is a potentially traumatizing experience that has devastating psychological and physical consequences. In response, domestic violence shelter programs have focused increasing attention on helping adult and child survivors understand and heal from this trauma. What have come to be called trauma-informed practices include (a) reflecting an understanding of trauma and its many effects on health and behavior, (b) addressing both physical and psychological safety concerns, (c) using a culturally informed strengths-based approach, (d) helping to illuminate the nature and effects of abuse on survivors' everyday experience; and (e) providing opportunities for clients to regain control over their lives...
August 17, 2017: American Journal of Orthopsychiatry
https://www.readbyqxmd.com/read/28815488/exploring-vaccine-hesitancy-through-an-artist-scientist-collaboration-visualizing-vaccine-critical-parents-health-beliefs
#5
Kaisu Koski, Johan Holst
This project explores vaccine hesitancy through an artist-scientist collaboration. It aims to create better understanding of vaccine hesitant parents' health beliefs and how these influence their vaccine-critical decisions. The project interviews vaccine-hesitant parents in the Netherlands and Finland and develops experimental visual-narrative means to analyse the interview data. Vaccine-hesitant parents' health beliefs are, in this study, expressed through stories, and they are paralleled with so-called illness narratives...
August 16, 2017: Journal of Bioethical Inquiry
https://www.readbyqxmd.com/read/28804813/a-systematic-review-of-the-clinical-applications-and-complications-of-bone-marrow-aspirate-concentrate-in-management-of-bone-defects-and-nonunions
#6
REVIEW
Mohamed A Imam, James Holton, Lukas Ernstbrunner, Wojciech Pepke, Florian Grubhofer, Ali Narvani, Martyn Snow
PURPOSE: Fracture healing encompasses a succession of dynamic multifactorial metabolic events, which ultimately re-establishes the integrity of the biomechanical properties of the bone. Up to 10% of the fractures occurring annually will need additional surgical procedures because of impaired healing. The aim of this article is to review the current literature regarding the use of bone marrow aspirate concentrate (BMAC) and its effectiveness in the management of bone defects. METHODS: We have included all published clinical literature investigating the development, techniques and applications of BMAC...
August 13, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28803244/how-to-become-an-agent-of-one-s-own-healing-processes-self-management-for-chronically-ill-patients-in-integrative-health-care
#7
Bettina Berger, Peter Heusser
No abstract text is available yet for this article.
August 15, 2017: Complementary Medicine Research
https://www.readbyqxmd.com/read/28803075/the-palliative-care-chaplain-as-story-catcher
#8
Rhonda S Cooper
The role of the professional chaplain on the palliative care team in the health care setting formalizes the concern for the emotional, spiritual and social well-being of the care recipients and their caregivers. The chaplain also has a peculiar role on the team, in that her most fundamental task is her intentional listening-and-hearing of the other person's story. One palliative chaplain introduces herself as a Story Catcher to care recipients, in an effort both to overcome the resistance some may have to her presence on the team and communicate her essential role and intent in providing spiritual care...
August 9, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28799692/logic-gate-functions-in-chemomechanical-materials
#9
REVIEW
Hans-Jörg Schneider
Chemomechanical polymers that change their shape or volume on stimulation by multiple external chemical signals, particularly on the basis of selective molecular recognition, are discussed. Several examples illustrate how such materials, usually in the form of hydrogels, can be used for the design of chemically triggered valves or artificial muscles and applied, for example, in self-healing materials or drug delivery. The most attractive feature of such materials is that they can combine sensor and actuator within single units, from nano- to macrosize...
August 11, 2017: Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry
https://www.readbyqxmd.com/read/28799236/tough-self-healing-elastomers-by-molecular-enforced-integration-of-covalent-and-reversible-networks
#10
Jinrong Wu, Li-Heng Cai, David A Weitz
Self-healing polymers crosslinked by solely reversible bonds are intrinsically weaker than common covalently crosslinked networks. Introducing covalent crosslinks into a reversible network would improve mechanical strength. It is challenging, however, to apply this concept to "dry" elastomers, largely because reversible crosslinks such as hydrogen bonds are often polar motifs, whereas covalent crosslinks are nonpolar motifs. These two types of bonds are intrinsically immiscible without cosolvents. Here, we design and fabricate a hybrid polymer network by crosslinking randomly branched polymers carrying motifs that can form both reversible hydrogen bonds and permanent covalent crosslinks...
August 11, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28798144/frontline-science-leishmania-mexicana-amastigotes-can-replicate-within-neutrophils
#11
Benjamin P Hurrell, Manon Beaumann, Sandrina Heyde, Ivo B Regli, Andreas J Müller, Fabienne Tacchini-Cottier
Cutaneous leishmaniasis is a neglected tropical disease, causing a spectrum of clinical manifestations varying from self-healing to unhealing lesions that may be very difficult to treat. Emerging evidence points to a detrimental role for neutrophils during the first hours following infection with many distinct Leishmania species (spp.) at a time when the parasite is in its nonreplicative promastigote form. Neutrophils have also been detected at later stages of infection in unhealing chronic cutaneous lesions...
August 10, 2017: Journal of Leukocyte Biology
https://www.readbyqxmd.com/read/28782360/self-healing-natural-rubber-with-tailorable-mechanical-properties-based-on-ionic-supramolecular-hybrid-network
#12
Chuanhui Xu, Liming Cao, Xunhui Huang, Yukun Chen, Baofeng Lin, Lihua Fu
In most cases, the strength of self-healing supramolecular rubber based on non-covalent bonds is in the order of KPa, which is a challenge for their further applications. Incorporation of conventional fillers can effectively enhance the strength of rubbers, but usually accompanied by a sacrifice of self-healing capability due to that the filler system is independent of the reversible supramolecular network. In the present work, in-situ reaction of methacrylic acid (MAA) and excess zinc oxide (ZnO) was realized in natural rubber (NR)...
August 7, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28782236/porous-titanium-scaffolds-with-self-assembled-micro-nano-hierarchical-structure-for-dual-functions-of-bone-regeneration-and-anti-infection
#13
Lu Han, Menghao Wang, Honglong Sun, Peifei Li, Kefeng Wang, Fuzeng Ren, Xiong Lu
Porous titanium (Ti) scaffolds are widely used for bone repair because of their good biocompatibility, mechanical properties and corrosion resistance. However, pristine Ti scaffolds are bioinert and unable to induce bone regeneration. In this study, chitosan coated BSA nanoparticles (CBSA NPs) and oxidized alginate (OSA) were in a layer-by-layer (LbL) manner on Ti scaffolds. The LbL film possessed micro/nano hierarchical architectures, has the features of nanostructures, and possesses abundant functional groups from CBSA NPs and OSA to improve the surface biocompatibility and biofunctionality of Ti scaffolds...
August 7, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28777486/intelligent-biodegradable-and-self-healing-hydrogels-utilizing-dna-quadruplexes
#14
Shizuma Tanaka, Kenta Wakabayashi, Kazuki Fukushima, Shinsuke Yukami, Ryuki Maezawa, Yuhei Takeda, Kohei Tatsumi, Yuichi Ohya, Akinori Kuzuya
A new class of hydrogels utilizing DNA (DNA quadruplex gel) has been constructed by directly and symmetrically coupling deoxynucleotide phosphoramidite monomers to the ends of polyethylene glycols (PEGs) in liquid phase, and using the resulting DNA-PEG-DNA triblock copolymers as macromonomers. Elongation of merely four deoxyguanosine residues on PEG, which produces typically ~10 grams of desired DNA-PEG conjugates in one synthesis, realized intelligent and biodegradable hydrogels utilizing DNA quadruplex formation, responsive to various input signals such as Na+, K+, and complementary DNA strand...
August 4, 2017: Chemistry, An Asian Journal
https://www.readbyqxmd.com/read/28774144/micromechanical-properties-of-a-new-polymeric-microcapsule-for-self-healing-cementitious-materials
#15
Leyang Lv, Erik Schlangen, Zhengxian Yang, Feng Xing
Self-healing cementitious materials containing a microencapsulated healing agent are appealing due to their great application potential in improving the serviceability and durability of concrete structures. In this study, poly(phenol-formaldehyde) (PF) microcapsules that aim to provide a self-healing function for cementitious materials were prepared by an in situ polymerization reaction. Size gradation of the synthesized microcapsules was achieved through a series of sieving processes. The shell thickness and the diameter of single microcapsules was accurately measured under environmental scanning electron microscopy (ESEM)...
December 20, 2016: Materials
https://www.readbyqxmd.com/read/28774052/evaluating-and-modeling-the-internal-diffusion-behaviors-of-microencapsulated-rejuvenator-in-aged-bitumen-by-ftir-atr-tests
#16
Junfeng Su, Yingyuan Wang, Peng Yang, Shan Han, Ningxu Han, Wei Li
Microencapsulated rejuvenator has been attracted much attention for self-healing bitumen. The diffusion coefficient is one of the key parameters to estimate the feasibility of rejuvenator to age bitumen. The objective of this research was to evaluate diffusion behaviors of microencapsulated rejuvenator in aged bitumen by a FTIR-ATR method. Various microcapsule samples were mixed in bitumen to form thin films. The core material of microcapsules used as rejuvenator was diphenylsilane (DPS), its fairly specific absorption band at 843 cm(-1) was selected as a marker band to calculate the diffusion coefficient (D)...
November 17, 2016: Materials
https://www.readbyqxmd.com/read/28773983/an-intriguing-method-for-fabricating-arbitrarily-shaped-matreshka-hydrogels-using-a-self-healing-template
#17
Takeshi Sato, Koichiro Uto, Takao Aoyagi, Mitsuhiro Ebara
This work describes an intriguing strategy for the creation of arbitrarily shaped hydrogels utilizing a self-healing template (SHT). A SHT was loaded with a photo-crosslinkable monomer, PEG diacrylate (PEGDA), and then ultraviolet light (UV) crosslinked after first shaping. The SHT template was removed by simple washing with water, leaving behind the hydrogel in the desired physical shape. A hierarchical 3D structure such as "Matreshka" boxes were successfully prepared by simply repeating the "self-healing" and "photo-irradiation" processes...
October 25, 2016: Materials
https://www.readbyqxmd.com/read/28773914/the-effect-of-4-octyldecyloxybenzoic-acid-on-liquid-crystalline-polyurethane-composites-with-triple-shape-memory-and-self-healing-properties
#18
Jianfeng Ban, Linjiang Zhu, Shaojun Chen, Yiping Wang
To better understand shape memory materials and self-healing materials, a new series of liquid-crystalline shape memory polyurethane (LC-SMPU) composites, named SMPU-OOBAm, were successfully prepared by incorporating 4-octyldecyloxybenzoic acid (OOBA) into the PEG-based SMPU. The effect of OOBA on the structure, morphology, and properties of the material has been carefully investigated. The results demonstrate that SMPU-OOBAm has liquid crystalline properties, triple-shape memory properties, and self-healing properties...
September 21, 2016: Materials
https://www.readbyqxmd.com/read/28772945/crack-extension-and-possibility-of-debonding-in-encapsulation-based-self-healing-materials
#19
Wenting Li, Zhengwu Jiang, Zhenghong Yang
The breakage of capsules upon crack propagation is crucial for achieving crack healing in encapsulation-based self-healing materials. A mesomechanical model was developed in this study to simulate the process of crack propagation in a matrix and the potential of debonding. The model used the extended finite element method (XFEM) combined with a cohesive zone model (CZM) in a two-dimensional (2D) configuration. The configuration consisted of an infinite matrix with an embedded crack and a capsule nearby, all subjected to a uniaxial remote tensile load...
May 27, 2017: Materials
https://www.readbyqxmd.com/read/28772785/in-situ-formation-of-decavanadate-intercalated-layered-double-hydroxide-films-on-aa2024-and-their-anti-corrosive-properties-when-combined-with-hybrid-sol-gel-films
#20
Junsheng Wu, Dongdong Peng, Yuntao He, Xiaoqiong Du, Zhan Zhang, Bowei Zhang, Xiaogang Li, Yizhong Huang
A layered double hydroxide (LDH) film was formed in situ on aluminum alloy 2024 through a urea hydrolysis method, and a decavanadate-intercalated LDH (LDH-V) film fabricated through the dip coating method. The microstructural and morphological characteristics were investigated by scanning electron microscopy (SEM). The corrosion-resistant performance was analyzed by electrochemical impedance spectroscopy (EIS), scanning electrochemical microscopy (SECM), and a salt-spray test (SST).The SEM results showed that a complete and defect-free surface was formed on the LDH-VS film...
April 18, 2017: Materials
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