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Hydroxyapatite

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https://www.readbyqxmd.com/read/29457695/functionalization-of-a-nanostructured-hydroxyapatite-with-copper-ii-compounds-as-pesticide-in-situ-tem-and-esem-observations-of-treated-vitis-vinifera-l-leaves
#1
Enrico Battiston, Maria C Salvatici, Alessandro Lavacchi, Antonietta Gatti, Stefano Di Marco, Laura Mugnai
BACKGROUND: The present study evaluates a biocompatible material for plant protection to reduce the amount of active substance applied. We used a synthetic hydroxyapatite (HA) that has been studied extensively due its bioactivity and biocompatibility. Aggregation between HA nanoparticles and four copper(II) compounds applied in Vitis vinifera L. leaves as pesticide was studied. Formulations were characterised by XRD, DLS, electron microscopy and applied in planta to verify the particle aggregation and efficiency in controlling the pathogen, Plasmopara viticola...
February 19, 2018: Pest Management Science
https://www.readbyqxmd.com/read/29457442/-development-and-application-of-artificial-vertebral-body
#2
REVIEW
Jian-Tao Liu, Feng Zhang, Zheng-Chao Gao, Bin-Bin Niu, Yu-Huan Li, Xi-Jing He
Artificial vertebral body has achieved good results in treating spinal tumors, tuberculosis, fracture and other diseases. Currently, artificial vertebral body with variety of kinds and pros and cons, is generally divided into two types: fusion type and movable type. The former according to whether the height could be adjusted and strength of self-stability is divided into three types: support-fixed type, adjust-fixed type and self-fixed type. Whether the height of self-fixed type could be adjusted is dependent on structure of collar thread rotation...
December 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29454808/a-new-multifunctionalized-material-against-multi-drug-resistant-bacteria-and-abnormal-osteoclast-activity
#3
Elisa Boanini, Paola Torricelli, Francesca Bonvicini, Maria Cristina Cassani, Milena Fini, Giovanna Angela Gentilomi, Adriana Bigi
The development of new biomaterials able to favor bone formation and to inhibit bone abnormal resorption is mandatory to face the increasing number of age-related musculo-skeletal disorders. Moreover, the increasing antibiotic resistance of clinically important bacteria, which is among the main causes of implant failure, requires new antimicrobial systems. In this study, we prepared multifunctional materials consisting of hydroxyapatite-zoledronate composite crystals decorated with Ag Nanoparticles (AgNPs)...
February 15, 2018: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/29454274/a-multifaceted-coating-on-titanium-dictates-osteoimmunomodulation-and-osteo-angio-genesis-towards-ameliorative-osseointegration
#4
Long Bai, Zhibin Du, Jingjing Du, Wei Yao, Jiaming Zhang, Zeming Weng, Si Liu, Ya Zhao, Yanlian Liu, Xiangyu Zhang, Xiaobo Huang, Xiaohong Yao, Ross Crawford, Ruiqiang Hang, Di Huang, Bin Tang, Yin Xiao
A multifaceted coating for hard tissue implants, with favorable osteogenesis, angiogenesis, and osteoimmunomodulation abilities, would be of great value since it could improve osseointegration and alleviate prosthesis loosening. However, to date there are few coatings that fully satisfy these criteria. Herein we describe a microporous TiO 2 coating decorated with hydroxyapatite (HA) nanoparticles that is generated by micro-arc oxidation of pure titanium (Ti) and followed annealing. By altering the annealing temperature, it is possible to simultaneously tune the coating's physical (morphology and wettability) and chemical (composites and crystallinity) properties...
February 6, 2018: Biomaterials
https://www.readbyqxmd.com/read/29451877/influence-of-hyperbaric-oxygen-on-biomechanics-and-structural-bone-matrix-in-type-1-diabetes-mellitus-rats
#5
Pedro Henrique Justino Oliveira Limirio, Huberth Alexandre da Rocha Junior, Richarlisson Borges de Morais, Karen Renata Nakamura Hiraki, Ana Paula Coelho Balbi, Priscilla Barbosa Ferreira Soares, Paula Dechichi
BACKGROUND: The aim of this study was to evaluate the biomechanics and structural bone matrix in diabetic rats subjected to hyperbaric oxygen therapy (HBO). METHODS: Twenty-four male rats were divided into the following groups: Control; Control + HBO; Diabetic, and Diabetic + HBO. Diabetes was induced with streptozotocin (STZ) in the diabetic Groups. After 30 days, HBO was performed every 48h in HBO groups and all animals were euthanized 60 days after diabetic induction...
2018: PloS One
https://www.readbyqxmd.com/read/29451708/promotion-of-bone-regeneration-on-titanium-implants-through-a-chemical-treatment-process-using-calcium-phosphate-slurry-microscopic-analysis-cellular-response-and-animal-experiment
#6
Tatsuro Ito, Naofumi Ohtsu, Masanari Tomozawa, Mitsuhiro Hirano, Hiroko Takita, Tadashi Iizuka, Atsuro Yokoyama
The present study provides scientific evidence that a new chemical treatment process using calcium phosphate slurry promotes bone regeneration on titanium (Ti) implants. The material's surface modified by the treatment was analyzed using microscopic observation and the bone regeneration efficacy was evaluated both in vitro and in vivo. Formation of a thin hydroxyapatite layer with a thickness of about 50 nm and an increase of surface roughness were confirmed by microscopic observations. Histological evaluation of rat femora implanted with the specimens showed that the areas of the specimens directly attached to bone tissue were significantly more extensive than those implanted with control Ti at 2 and 8 weeks...
February 16, 2018: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29450775/simultaneous-immobilization-of-cadmium-and-lead-in-contaminated-soils-by-hybrid-bio-nanocomposites-of-fungal-hyphae-and-nano-hydroxyapatites
#7
Zhihui Yang, Lifen Liang, Weichun Yang, Wei Shi, Yunping Tong, Liyuan Chai, Shikang Gao, Qi Liao
Self-aggregation of bulk nano-hydroxyapatites (n-HAPs) undermines their immobilization efficiencies of heavy metals in the contaminated soils. Here, the low-cost, easily obtained, and environment-friendly filamentous fungi have been introduced for the bio-matrices of the hybrid bio-nanocomposites to potentially solve such problem of n-HAPs. According to SEM, TEM, XRD, and FT-IR analyses, n-HAPs were successfully coated onto the fungal hyphae and their self-aggregation was improved. The immobilization efficiencies of diethylene-triamine-pentaacetic acid (DTPA)-extractable Cd and Pb in the contaminated soils by the bio-nanocomposites were individually one to four times of that by n-HAPs or the fungal hyphae...
February 15, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29448712/a-simulated-body-fluid-evaluation-of-tio%C3%A2-barrier-oxide-layer-formed-by-electrochemical-reaction
#8
Jae-Myung Jang, Tae-Eon Park, Seung-Dai Kim, Han-Cheol Choe
The modified surface during implantation is considered to be an effective strategy to improve high adhesion of bone cell and osseointegration activity. In this paper, the TiO2 barrier oxide Layer has been fabricated by using the ion characteristic of an electrolytic solution, the surface characteristics have been investigated by EDS, XPS, and FE-SEM. From the analysis of the chemical states, phosphorus and calcium were observed in the TiO2 barrier layer, which were penetrated from the electrolyte into the oxide layer during deposit process...
March 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29448678/fabrication-and-friction-coefficient-of-graphene-oxide-reinforced-hydroxyapatite-composite
#9
Ming Gong, Qian Zhao, Liming Dai, Yingying Li, Tingshun Jiang
Graphene oxide (GO) reinforced hydroxyapatite (HA) composites with various contents of GO (HA/GO-C) were synthesized with addition of cetyltrimethyl ammonium bromide (CTAB) by a wetchemical precipitation method using diammonium hydrogen phosphate ((NH4)2HPO4) and calcium nitrate (Ca(NO3)2 · 4H2O) as the initial reactants, and their structure, morphology, crystallization, specific surface area were studied by FT-IR, SEM, Raman spectroscopy, XRD and BET. Particularly, the influence of GO addition and appiled load on the friction coefficient of the obtained composites was investigated...
March 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29448611/electrochemical-deposition-of-hydroxyapatite-substituted-with-magnesium-and-strontium-on-ti-6al-4v-alloy
#10
Kang Lee, Yeong-Mu Ko, Han-Cheol Choe
In the present study, electrochemical deposition of hydroxyapatite substituted with magnesium and strontium on Ti-6Al-4V alloy have investigated. Mg and Sr-doped HAp was coated using subsequently pulsed electrochemical deposition process at 85 °C in the solution contained Ca, Mg, Sr, and P ion. The morphology of Mg/Sr-HAp formed on implant was investigated using scanning electron microscopy and X-ray diffraction. HAp grain size and XRD intensity decreased with Mg2+ and Sr2+ ions. The initial current density was changed with addition of Mg and Sr ion concentration when the constant voltage was applied to specimens...
February 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29448609/pore-shape-changes-and-apatite-formation-on-zn-and-si-ion-doped-ha-films-of-ti-6al-4v-after-plasma-electrolytic-oxidation-treatment
#11
In-Jo Hwang, Han-Cheol Choe
In this study, pore shape changes and apatite formation on zinc (Zn) and silicon (Si) ion-doped hydroxyapatite (HA) films of Ti-6Al-4V by plasma electrolytic oxidation (PEO) treatment has been investigated by several techniques. The PEO films and the Ti-6Al-4V surface after immersion in SBF were observed by X-ray spectroscopy, field-emission scanning electron microscopy, and energy dispersive X-ray spectroscopy. The number of pores decreased as Zn ion concentration increased from 5Zn to 10Zn. The maximum size of pores were increased from 5Zn to 20Zn concentration, whereas, the minimum size of pores decreased...
February 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29448608/bone-like-apatite-formation-on-the-plasma-electrolytic-oxidation-treated-ti-6al-4v-alloy-in-solution-containing-si-and-mg-ions
#12
Seon-Yeong Park, D Han-Cheol Choe
The bon-like apatite formation on the plasma electrolytic oxidation (PEO)-treated Ti-6Al-4V alloy in solution containing Si and Mg ions was studied using various experimental techniques. A Ti-6Al-4V ELI disk and implant was used as a substrate for PEO. A pulsed DC power supply was used to apply a potential of 280 V in the electrolyte for 3 min. To examine the bioactivity, the PEO films formed implant specimens were immersed in a simulated body fluid (SBF) for 12 h. PEO-treated surface has large micro-pores and small micro-pores, and 5 Mg/Si and 20 Mg/Si coated surfaces showed the more small micro-pores than that of CaP coated surface...
February 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29448599/hydroxyapatite-coating-on-tio%C3%A2-nanotube-by-sol-gel-method-for-implant-applications
#13
Hyun-Pil Lim, Sang-Won Park, Kwi-Dug Yun, Chan Park, Min-Kyung Ji, Gye-Jeong Oh, Jong-Tak Lee, Kwangmin Lee
The aim of this study was to determine the effect of hydroxyapatite (HA) coating on titanium dioxide (TiO2) nanotube by sol-gel process on viability of osteoblast like cell (MC3T3-E1) and bone formation in rat tibia. Specimens were divided into three groups including commercially pure titanium (control group), TiO2 nanotubes (group N), and HA coated TiO2 nanotubes (group HN). Surface characteristics were determined using field emission scanning electron microscope (FE-SEM; S-4700, Hitachi, Japan) and contact angles were measured...
February 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29448578/oxygen-and-acrylic-acid-plasma-treatment-on-titanium-mesh-for-improving-the-hydroxyapatite-formation
#14
Youngseung Park, Byung-Hoon Kim, Seon-Ju Lee, Hong-Ju Park, Hee-Kyun Oh, Myung-Sun Kim, Min-Suk Kook
Customized titanium (Ti) meshes were treated with O2 plasma and acrylic acid plasmapolymerization (PPAAc). The optimum conditions for PPAAc were as follows: 20 W, 15 mTorr, and 5 min. Hydroxyapatite formation increased in Ti meshes treated with O2 and PPAAc compared with that in untreated Ti meshes. Moreover, MC3T3-E1 cells exhibited improved cell spreading, attachment, proliferation in PPAAc treated Ti mesh than in untreated Ti mesh. This result revealed that O2 and PPAAc surface treatment on Ti mesh was potential tool for improving the bone formation on the Ti mesh clinically application...
February 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29448502/-in-vitro-mechanical-performance-study-of-biodegradable-polylactic-acid-hydroxyapatite-nanocomposites-for-fixation-medical-devices
#15
Jinsu Park, Bae-Jung Kim, Ji-Yeong Hwang, Yo-Woong Yoon, Hoon-Sang Cho, Dong-Hyun Kim, Jong Kook Lee, Seog-Young Yoon
Osteoconductive, biocompatible, and resorbable organic/inorganic composites are most commonly used in fixation medical devices, such as suture anchors and interference screws, because of their unique physical and chemical properties. Generally, studies on biodegradable composites have focused on their mechanical properties based on the composition and the individual roles of organic and inorganic biomaterials. In this study, we prepared biodegradable organic/inorganic nanocomposite materials using the solvent mixing process and conventional molding...
February 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29448501/hydroxyapatite-coatings-containing-mn-and-si-on-the-oxidized-ti-6al-4v-alloy-for-dental-applications
#16
Jung-In Kang, Mee-Kyoung Son, Han-Cheol Choe
The purpose of this study was to investigate hydroxyapatite coatings containing Mn and Si on the oxidized Ti-6Al-4V alloy for dental applications. Dental implant fixture and Ti-6Al-4V ELI disk were used as substrates for plasma electrolytic oxidation (PEO) treatment. PEO treatment was performed at 280 V for 3 min in various solutions. The surface morphologies of the specimens after PEO treatment were observed with a field-emission scanning electron microscope, energy-dispersive X-ray spectroscopy, X-ray diffractometer, and Fourier transform infrared spectroscopy...
February 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29447478/dendritic-platforms-for-biomimicry-and-biotechnological-applications
#17
Kalpana Nagpal, Anand Mohan, Sourav Thakur, Pradeep Kumar
Dendrimers, commonly referred to as polymeric trees, offer endless opportunities for biotechnological and biomedical applications. By controlling the type, length, and molecular weight of the core, branches and end groups, respectively, the chemical functionality and topology of dendrimeric archetypes can be customized which further can be applied to achieve required solubility, biodegradability, diagnosis and other applications. Given the physicochemical variability of the dendrimers and their hybrids, this review attempts to discuss a full spectrum of recent advances and strides made by these "perfectly designed structures"...
February 15, 2018: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/29444673/effect-of-tt-farnesol-and-myricetin-on-in-vitro-biofilm-formed-by-streptococcus-mutans-and-candida-albicans
#18
Guilherme Roncari Rocha, Elkin Jahir Florez Salamanca, Ana Letícia de Barros, Carmélia Isabel Vitorino Lobo, Marlise Inêz Klein
BACKGROUND: Dental caries is considered a multifactorial disease, in which microorganisms play an important role. The diet is decisive in the biofilm formation because it provides the necessary resources for cellular growth and exopolysaccharides synthesis. Exopolysaccharides are the main components of the extracellular matrix (ECM). The ECM provides a 3D structure, support for the microorganisms and form diffusion-limited environments (acidic niches) that cause demineralization of the dental enamel...
February 14, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29444198/alveolar-ridge-augmentation-with-three-dimensional-printed-hydroxyapatite-devices-a-preclinical-study
#19
Joseph P Fiorellini, Michael R Norton, Kevin WanXin Luan, David Minjoon Kim, Kei Wada, Hector L Sarmiento
The objective of this study was to evaluate the effectiveness of precise three-dimensional hydroxyapatite printed micro- and macrochannel devices for alveolar ridge augmentation in a canine model. All grafts induced minimal inflammatory and fibrotic reactions. Examination of undecalcified sections revealed that both types of grafts demonstrated bone ingrowth. The majority of the bone growth into the block graft was into the channels, though a portion grew directly into the construct in the form of small bony spicules...
February 14, 2018: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/29442898/development-of-egg-shell-derived-carbonated-apatite-nanocarrier-system-for-drug-delivery
#20
R Jayasree, K Madhumathi, Deepti Rana, Murugan Ramalingam, Rakesh P Nankar, Mukesh Doble, T S Sampath Kumar
Carbonated apatite has a chemical composition quite similar to biological apatite found in native bone. The incorporation of carbonate (CO2-3) ions groups into the apatitic crystal structure can tailor its crystallinity, solubility and biological activity that benefit the bone repair and regeneration. In this study, we report a simple and elegant method of synthesizing carbonated calcium deficient hydroxyapatite (ECCDHA) nanoparticles from egg shell wastes and its efficacy has been compared with synthetic calcium deficient hydroxyapatite (SCDHA) nanoparticles...
April 1, 2018: Journal of Nanoscience and Nanotechnology
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