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Bow tie analysis

Siobhán Corrigan, Alison Kay, Katie O'Byrne, Dubhfeasa Slattery, Sharon Sheehan, Nick McDonald, David Smyth, Ken Mealy, Sam Cromie
A Retained Foreign Object (RFO) is a fairly infrequent but serious adverse event. An accurate rate of RFOs is difficult to establish due to underreporting but it has been estimated that incidences range between 1/1000 and 1/19,000 procedures. The cost of a RFO incident may be substantial and three-fold: (i) the cost to the patient of physical and/or psychological harm; (ii) the reputational cost to an institution and/or healthcare provider; and (iii) the financial cost to the taxpayer in the event of a legal claim...
April 10, 2018: International Journal of Environmental Research and Public Health
Qingwei Xu, Kaili Xu
Mine safety assessment is a precondition for ensuring orderly and safety in production. The main purpose of this study was to prevent mine accidents more effectively by proposing a composite risk analysis model. First, the weights of the assessment indicators were determined by the revised integrated weight method, in which the objective weights were determined by a variation coefficient method and the subjective weights determined by the Delphi method. A new formula was then adopted to calculate the integrated weights based on the subjective and objective weights...
2018: PloS One
Tyler W H Backman, David Ando, Jahnavi Singh, Jay D Keasling, Héctor García Martín
Determination of internal metabolic fluxes is crucial for fundamental and applied biology because they map how carbon and electrons flow through metabolism to enable cell function. 13 C Metabolic Flux Analysis ( 13 C MFA) and Two-Scale 13 C Metabolic Flux Analysis (2S- 13 C MFA) are two techniques used to determine such fluxes. Both operate on the simplifying approximation that metabolic flux from peripheral metabolism into central "core" carbon metabolism is minimal, and can be omitted when modeling isotopic labeling in core metabolism...
January 4, 2018: Metabolites
Maria Mikela Chatzimichailidou, James Ward, Tim Horberry, P John Clarkson
Although relatively rare, surgical instrument retention inside a patient following central venous catheterization still presents a significant risk. The research presented here compared two approaches to help reduce retention risk: Bow-Tie Analysis and Systems-Theoretic Accident Model and Processes. Each method was undertaken separately and then the results of the two approaches were compared and combined. Both approaches produced beneficial results that added to existing domain knowledge, and a combination of the two methods was found to be beneficial...
November 6, 2017: Risk Analysis: An Official Publication of the Society for Risk Analysis
Laura J Vera Stimpson, Silvia Ramos, Gavin B G Stenning, Marek Jura, Stephen Parry, Giannantonio Cibin, Donna C Arnold
Ca2 Mn3 O8 exhibits a complex layered structure comprised of Mn3 O8 4- layers separated by Ca2+ ions. In contrast with the more traditional triangular delafossite layered materials the Mn3 O8 4- layers additionally exhibit an ordered vacancy, which forms a 'bow-tie' like arrangement of the Mn4+ ions. We report a comprehensive study of the magnetic properties of a series of Ca2 Mn3 O8 materials with different morphologies. EXAFS and XANES analysis confirm no differences in either manganese environment or oxidation state between materials...
October 24, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
Kang Min Sohn, Min Jin Lee, Helen Hong, Young Cheol Yoon, Chan Deok Park, Joon Ho Wang
BACKGROUND: Although numerous studies have examined the anatomic characteristics of the anterior cruciate ligament (ACL), its actual shape remains unclear. PURPOSE: To determine the average shape of the ACL by analyzing its cross section through the use of high-resolution magnetic resonance imaging (MRI) data. STUDY DESIGN: Descriptive laboratory study. METHODS: The study included 96 MRIs, conducted using a 3.0-T magnet, to analyze the shape of the ACL...
July 2017: American Journal of Sports Medicine
Hannah Scott, Mark F Rogers, Helen L Scott, Colin Campbell, Elizabeth C Warburton, James B Uney
We have used transcriptome analysis to identify genes and pathways that are activated during recognition memory formation in the perirhinal cortex. Rats were exposed to objects either repeatedly, so that the objects become familiar, or to novel objects in a bow-tie maze over six consecutive days. On the final day, one hour after the last exposure to the series of objects, RNA from the perirhinal cortex was sequenced to compare the transcriptome of naïve control rats and rats exposed to either novel or familiar stimuli...
June 15, 2017: Behavioural Brain Research
M D Culwick, A F Merry, D M Clarke, K J Taraporewalla, N M Gibbs
Bow-tie analysis is a risk analysis and management tool that has been readily adopted into routine practice in many high reliability industries such as engineering, aviation and emergency services. However, it has received little exposure so far in healthcare. Nevertheless, its simplicity, versatility, and pictorial display may have benefits for the analysis of a range of healthcare risks, including complex and multiple risks and their interactions. Bow-tie diagrams are a combination of a fault tree and an event tree, which when combined take the shape of a bow tie...
November 2016: Anaesthesia and Intensive Care
Esmaeil Zarei, Ali Azadeh, Nima Khakzad, Mostafa Mirzaei Aliabadi, Iraj Mohammadfam
Pipelines are one of the most popular and effective ways of transporting hazardous materials, especially natural gas. However, the rapid development of gas pipelines and stations in urban areas has introduced a serious threat to public safety and assets. Although different methods have been developed for risk analysis of gas transportation systems, a comprehensive methodology for risk analysis is still lacking, especially in natural gas stations. The present work is aimed at developing a dynamic and comprehensive quantitative risk analysis (DCQRA) approach for accident scenario and risk modeling of natural gas stations...
January 5, 2017: Journal of Hazardous Materials
Yong Hyun Kim, Hong Kwon, Jeongjun Kim, Kwang Yong Song
High-sensitivity distributed measurement of hydrostatic pressure is experimentally demonstrated by optical time-domain analysis of Brillouin dynamic grating (BDG) in polarization maintaining fibers (PMF's). The spectral shift of the BDG in four different types of PMF's are investigated under hydrostatic pressure variation from 14.5 psi (1 bar) to 884.7 psi (61 bar) with less than 2 m spatial resolution. The pressure sensitivity of BDG frequency is measured to be ‒1.69, + 0.65, + 0.78, and + 0.85 MHz/psi for a PM photonic crystal fiber (PM-PCF), two Bow-tie fibers, and a PANDA fiber, respectively, which is about 65 to 169 times larger than that of Brillouin frequency-based pressure sensing...
September 19, 2016: Optics Express
Fang Yan, Kaili Xu, Xiwen Yao, Yang Li
Biomass gasification technology has been rapidly developed recently. But fire and poisoning accidents caused by gas leakage restrict the development and promotion of biomass gasification. Therefore, probabilistic safety assessment (PSA) is necessary for biomass gasification system. Subsequently, Bayesian network-bow-tie (BN-bow-tie) analysis was proposed by mapping bow-tie analysis into Bayesian network (BN). Causes of gas leakage and the accidents triggered by gas leakage can be obtained by bow-tie analysis, and BN was used to confirm the critical nodes of accidents by introducing corresponding three importance measures...
2016: PloS One
Tomonobu Haba, Shuji Koyama, Yutaka Kinomura, Yoshihiro Ida, Masanao Kobayashi
The American Association of Physicists in Medicine (AAPM) task group 204 has recommended the use of size-dependent conversion factors to calculate size-specific dose estimate (SSDE) values from volume computed tomography dose index (CTDIvol) values. However, these conversion factors do not consider the effects of 320-detector-row volume computed tomography (CT) examinations or the new CT dosimetry metrics proposed by AAPM task group 111. This study aims to investigate the influence of these examinations and metrics on the conversion factors reported by AAPM task group 204, using Monte Carlo simulations...
September 2016: Australasian Physical & Engineering Sciences in Medicine
Ali Mirzajani, Sattar Aghataheri, Mohammad Ghoreishi, Ebrahim Jafarzadepour, Mohadese Mohammadinia
PURPOSE: This study reports the characteristics of corneal higher order aberrations (HOAs) in eyes with normal topographic pattern using the Pentacam scheimpflug system. METHODS: In this prospective, observational, comparative study, 165 eyes of 97 patients separated into five groups based on corneal topographic patterns were enrolled. All eyes received a comprehensive ophthalmologic examination including corneal tomographic analysis with the Pentacam system. Keratometry, corneal cylinder, and corneal aberrometric data were recorded and analyzed...
June 2016: Journal of Current Ophthalmology
Zhaleh Abdi, Hamid Ravaghi, Mohsen Abbasi, Bahram Delgoshaei, Somayeh Esfandiari
Purpose - The purpose of this paper is to apply Bow-tie methodology, a proactive risk assessment technique based on systemic approach, for prospective analysis of the risks threatening patient safety in intensive care unit (ICU). Design/methodology/approach - Bow-tie methodology was used to manage clinical risks threatening patient safety by a multidisciplinary team in the ICU. The Bow-tie analysis was conducted on incidents related to high-alert medications, ventilator associated pneumonia, catheter-related blood stream infection, urinary tract infection, and unwanted extubation...
May 9, 2016: International Journal of Health Care Quality Assurance
Assim Boukhayma, Antoine Dupret, Jean-Pierre Rostaing, Christian Enz
This paper presents the first low noise complementary metal oxide semiconductor (CMOS) deletedCMOS terahertz (THz) imager based on source modulation and in-pixel high-Q filtering. The 31 × 31 focal plane array has been fully integrated in a 0 . 13 μ m standard CMOS process. The sensitivity has been improved significantly by modulating the active THz source that lights the scene and performing on-chip high-Q filtering. Each pixel encompass a broadband bow tie antenna coupled to an N-type metal-oxide-semiconductor (NMOS) detector that shifts the THz radiation, a low noise adjustable gain amplifier and a high-Q filter centered at the modulation frequency...
2016: Sensors
Khalique Newaz, K Sriram, Debajyoti Bera
Prion diseases are transmissible neurodegenerative diseases that arise due to conformational change of normal, cellular prion protein (PrPC) to protease-resistant isofrom (rPrPSc). Deposition of misfolded PrpSc proteins leads to an alteration of many signaling pathways that includes immunological and apoptotic pathways. As a result, this culminates in the dysfunction and death of neuronal cells. Earlier works on transcriptomic studies have revealed some affected pathways, but it is not clear which is (are) the prime network pathway(s) that change during the disease progression and how these pathways are involved in crosstalks with each other from the time of incubation to clinical death...
2015: PloS One
Nima Abedpour, Markus Kollmann
BACKGROUND: A universal feature of metabolic networks is their hourglass or bow-tie structure on cellular level. This architecture reflects the conversion of multiple input nutrients into multiple biomass components via a small set of precursor metabolites. However, it is yet unclear to what extent this structural feature is the result of natural selection. RESULTS: We extend flux balance analysis to account for limited cellular resources. Using this model, optimal structure of metabolic networks can be calculated for different environmental conditions...
2015: BMC Systems Biology
Bruce R Whiting, Joshua D Evans, Andreea C Dohatcu, Jeffrey F Williamson, David G Politte
PURPOSE: Several areas of computed tomography (CT) research require knowledge about the intensity profile of the x-ray fan beam that is introduced by a bow tie filter. This information is considered proprietary by CT manufacturers, so noninvasive measurement methods are required. One method using real-time dosimeters has been proposed in the literature. A commercially available dosimeter was used to apply that method, and analysis techniques were developed to extract fan beam profiles from measurements...
October 2014: Medical Physics
Zhi Yuan, Nima Khakzad, Faisal Khan, Paul Amyotte
In this study, a methodology has been proposed for risk analysis of dust explosion scenarios based on Bayesian network. Our methodology also benefits from a bow-tie diagram to better represent the logical relationships existing among contributing factors and consequences of dust explosions. In this study, the risks of dust explosion scenarios are evaluated, taking into account common cause failures and dependencies among root events and possible consequences. Using a diagnostic analysis, dust particle properties, oxygen concentration, and safety training of staff are identified as the most critical root events leading to dust explosions...
February 2015: Risk Analysis: An Official Publication of the Society for Risk Analysis
D W Ding, Y R Ding, L N Li, Y J Cai, W B Xu
The purpose of this work was to study the giant strong component (GSC) of B. thuringiensis metabolic network by structural and functional analysis. Based on so-called "bow tie" structure, we extracted and studied GSC with its functional significance. Global structural properties such as degree distribution and average path length were computed and indicated that the GSC is also a small-world and scale-free network. Furthermore, the GSC was decomposed and functional significant for metabolism of these divisions were investigated by comparing to KEGG metabolic pathways...
April 2009: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
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