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Khalid Alhabib

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https://www.readbyqxmd.com/read/28871820/acute-heart-failure-presentations-and-outcomes-during-the-fasting-month-of-ramadan-an-observational-report-from-seven-middle-eastern-countries
#1
Amar M Salam, Kadhim Sulaiman, Alawi A Alsheikh-Ali, Rajvir Singh, Nidal Asaad, Awad Al-Qahtani, Imtiaz Salim, Khalid F AlHabib, Ibrahim Al-Zakwani, Mohammed Al-Jarallah, Wael AlMahmeed, Bassam Bulbanat, Mustafa Ridha, Nooshin Bazargani, Haitham Amin, Ahmed Al-Motarreb, Husam AlFaleh, Hanan Albackr, Prashanth Panduranga, Abdulla Shehab, Jassim Al Suwaidi
BACKGROUND: Fasting during the month of Ramadan is practiced by over one and a half billion Muslims worldwide. It remains unclear, however, how this change in lifestyle affects heart failure, a condition that has reached epidemic dimensions. We examined the effects of fasting in patients with acute heart failure (AHF) using data from a large multi-center heart failure registry. METHODS AND RESULTS: Data were derived from Gulf CARE (Gulf aCute heArt failuRe rEgistry), a prospective multicenter study of consecutive patients hospitalized with AHF during February-November 2012...
September 5, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28868092/the-spectrum-of-familial-hypercholesterolemia-fh-in-saudi-arabia-prime-time-for-patient-fh-registry
#2
REVIEW
Faisal Alallaf, Fatima Amanullah H Nazar, Majed Alnefaie, Adel Almaymuni, Omran Mohammed Rashidi, Khalid Alhabib, Fahad Alnouri, Mohamed-Nabil Alama, Mohammad Athar, Zuhier Awan
BACKGROUND: Familial hypercholesterolemia (FH) is a life-threatening inherited condition. Untreated patients have the risk to develop raised plasma levels of cholesterol, atherosclerosis and cardiovascular disease (CVD). If diagnosed and treated early in life, the pathological consequences due to atherosclerosis could be avoided and patients with FH can have an anticipated normal life. Mounting evidence suggests that FH is underdiagnosed and undertreated in all populations. The underlying molecular basis of FH is the presence of mutations in one or more genes in the low-density lipoprotein receptor (LDLR), apolipoprotein B (APOB) or proprotein convertase subtilisin/kexin 9 (PCSK9)...
2017: Open Cardiovascular Medicine Journal
https://www.readbyqxmd.com/read/28820057/impact-of-angiotensin-converting-enzyme-inhibitors-angiotensin-receptors-blockers-on-mortality-in-acute-heart-failure-patients-with-left-ventricular-systolic-dysfunction-in-the-middle-east-observations-from-the-gulf-acute-heart-failure-registry-gulf-care
#3
Ibrahim Al-Zakwani, Kadhim Sulaiman, Jawad A Al-Lawati, Alawi A Alsheikh-Ali, Prashanth Panduranga, Khalid F AlHabib, Jassim Al Suwaidi, Wael Al-Mahmeed, Hussam AlFaleh, Abdelfatah Elasfar, Ahmed Al-Motarreb, Mustafa Ridha, Bassam Bulbanat, Mohammed Al-Jarallah, Nooshin Bazargani, Nidal Asaad, Haitham Amin
AIMS: To evaluate the impact of angiotensin-converting enzyme inhibitors (ACEIs)/angiotensin receptors blockers (ARBs) on in-hospital, 3- and 12-month all-cause mortality in acute heart failure (AHF) patients with left ventricular systolic dysfunction in 7 countries of the Middle East. METHODS AND RESULTS: Data was analysed from 2,683 consecutive patients admitted with AHF and low ventricular ejection fraction (LVEF) (<40%) from 47 hospitals from February to November, 2012...
August 17, 2017: Current Vascular Pharmacology
https://www.readbyqxmd.com/read/28817709/assessment-of-physicians-awareness-and-knowledge-of-familial-hypercholesterolemia-in-saudi-arabia-is-there-a-gap
#4
Mohammed Ali Batais, Turky H Almigbal, Aref A Bin Abdulhak, Hani B Altaradi, Khalid F AlHabib
BACKGROUND: The scarcity of familial hypercholesterolemia (FH) cases reported in Saudi Arabia might be indicative of a lack of awareness of this common genetic disease among physicians. OBJECTIVE: To assess physicians' awareness, practice, and knowledge of FH in Saudi Arabia. METHODS: This is a cross-sectional study conducted among physicians at four tertiary hospitals in Riyadh, Saudi Arabia between March 2016 and May 2016 using a self-administered questionnaire...
2017: PloS One
https://www.readbyqxmd.com/read/28750542/clinical-presentation-predictors-and-outcomes-among-mineralocorticoid-receptor-antagonist-mra-eligible-acute-heart-failure-patients-in-the-heart-function-assessment-registry-trial-in-saudi-arabia-hearts
#5
Mostafa Q AlShamiri, Khalid F AlHabib, Waleed AlHabeeb, Ismail R Raslan, Anhar Ullah, Abdelfatah A Elasfar, Fayez Alshaer, Hanan Albackr, Layth Mimish, Ali Almasood, Saleh AlGhamdi, Abdullah Ghabashi
Mineralocorticoid receptor antagonist (MRA) therapy is indicated after myocardial infarction in patients with acute heart failure (AHF) with an ejection fraction ≤40% and lacking contraindications. We analyzed clinical presentations, predictors, and outcomes of MRA-eligible patients within a prospective registry of patients with AHF from 18 hospitals in Saudi Arabia, from 2009 to 2010. For this subgroup, mortality rates were followed until 2013, and the clinical characteristics, management, predictors, and outcomes were compared between MRA-treated and non-MRA-treated patients...
January 1, 2017: Angiology
https://www.readbyqxmd.com/read/28694343/non-withdrawal-of-beta-blockers-in-acute-decompensated-chronic-and-de-novo-heart-failure-with-reduced-ejection-fraction-in-a-prospective-multicentre-study-of-patients-with-acute-heart-failure-in-the-middle-east
#6
Charbel Abi Khalil, Kadhim Sulaiman, Ziyad Mahfoud, Rajvir Singh, Nidal Asaad, Khalid F AlHabib, Alawi Alsheikh-Ali, Mohammed Al-Jarallah, Bassam Bulbanat, Wael AlMahmeed, Mustafa Ridha, Nooshin Bazargani, Haitham Amin, Ahmed Al-Motarreb, Husam Al Faleh, Abdelfatah Elasfar, Prashanth Panduranga, Jassim Al Suwaidi
OBJECTIVES: Beta blockers reduce mortality in heart failure (HF). However, it is not clear whether they should be temporarily withdrawn during acute HF. DESIGN: Analysis of prospectively collected data. SETTING: The Gulf aCute heArt failuRe rEgistry is a prospective multicentre study of patients hospitalised with acute HF in seven Middle Eastern countries. PARTICIPANTS: 5005 patients with acute HF. OUTCOME MEASURES: We studied the effect of beta blockers non-withdrawal on intrahospital, 3-month and 12-month mortality and rehospitalisation for HF in patients with acute decompensated chronic heart failure (ADCHF) and acute de novo heart failure (ADNHF) and a left ventricular ejection fraction (LVEF) <40%...
July 9, 2017: BMJ Open
https://www.readbyqxmd.com/read/28674721/attitude-of-the-saudi-community-towards-heart-donation-transplantation-and-artificial-hearts
#7
Waleed AlHabeeb, Fakhr AlAyoubi, Adel Tash, Leenah AlAhmari, Khalid F AlHabib
To understand the attitudes of the Saudi population towards heart donation and transplantation. Methods: A survey using a questionnaire addressing attitudes towards organ transplantation and donation was conducted across 18 cities in Saudi Arabia between September 2015 and March 2016.  Results: A total of 1250 respondents participated in the survey. Of these, approximately 91% agree with the concept of organ transplantation but approximately 17% do not agree with the concept of heart transplantation; 42...
July 2017: Saudi Medical Journal
https://www.readbyqxmd.com/read/28592150/atrial-fibrillation-in-patients-hospitalized-with-heart-failure-patient-characteristics-and-outcomes-from-the-hearts-registry
#8
M Ajlan, L Almazroa, Khalid F AlHabib, Abdelfatah A Elasfar, Hussam Alfaleh, Hanan Albackr, Tarek Kashour, Ahmad Hersi, Gamal A Hussein, Layth Mimish, Ali Almasood, Waleed AlHabeeb, Saleh AlGhamdi, Mubrouk Alsharari, Esmail Chakra, Asif Malik, Raza Soomro, Abdullah Ghabashi, Mushabab Al-Murayeh, Ahmed Abuosa
Effect of atrial fibrillation (AF) on short- and long-term outcomes in heart failure (HF) is controversial. Accordingly, we examined this relationship in a national multicenter project using data from the Hearts Function Assessment Registry Trial in Saudi Arabia that studied the clinical features and outcomes of patients admitted with de novo and acute on chronic HF. Out of 2593 patients with HF, 449 (17.8%) had AF at presentation. Patients with AF were more likely to be males and older (mean age 65.2 ± 15...
January 1, 2017: Angiology
https://www.readbyqxmd.com/read/28486270/prevalence-awareness-treatment-and-control-of-hypertension-in-four-middle-east-countries
#9
Afzalhussein M Yusufali, Rasha Khatib, Shofiqul Islam, Khalid F Alhabib, Ahmad Bahonar, Hani M Swidan, Umaiyeh Khammash, Mostafa Q Alshamiri, Sumathy Rangarajan, Salim Yusuf
OBJECTIVE: We report the prevalence, awareness, treatment, and control of hypertension across four Middle Eastern countries (Iran, Occupied Palestinian Territory, Saudi Arabia, and United Arab Emirates), using a standardized and uniform method. METHODS: The Prospective Urban Rural Epidemiology study enrolled participants from 52 urban and 35 rural communities from four countries in the Middle East. We report results using definitions of hypertension, prevalence, awareness, treatment, and control, and the standards for uniform reporting of hypertension in adults as recently recommended by the World Hypertension League expert committee...
July 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28476564/global-mortality-variations-in-patients-with-heart-failure-results-from-the-international-congestive-heart-failure-inter-chf-prospective-cohort-study
#10
Hisham Dokainish, Koon Teo, Jun Zhu, Ambuj Roy, Khalid F AlHabib, Ahmed ElSayed, Lia Palileo-Villaneuva, Patricio Lopez-Jaramillo, Kamilu Karaye, Khalid Yusoff, Andres Orlandini, Karen Sliwa, Charles Mondo, Fernando Lanas, Dorairaj Prabhakaran, Amr Badr, Mohamed Elmaghawry, Albertino Damasceno, Kemi Tibazarwa, Emilie Belley-Cote, Kumar Balasubramanian, Shofiqul Islam, Magdi H Yacoub, Mark D Huffman, Karen Harkness, Alex Grinvalds, Robert McKelvie, Shrikant I Bangdiwala, Salim Yusuf
BACKGROUND: Most data on mortality and prognostic factors in patients with heart failure come from North America and Europe, with little information from other regions. Here, in the International Congestive Heart Failure (INTER-CHF) study, we aimed to measure mortality at 1 year in patients with heart failure in Africa, China, India, the Middle East, southeast Asia and South America; we also explored demographic, clinical, and socioeconomic variables associated with mortality. METHODS: We enrolled consecutive patients with heart failure (3695 [66%] clinic outpatients, 2105 [34%] hospital in patients) from 108 centres in six geographical regions...
May 3, 2017: Lancet Global Health
https://www.readbyqxmd.com/read/28291623/bmi-is-inversely-correlated-to-the-risk-of-mortality-in-patients-with-type-2-diabetes-hospitalized-for-acute-heart-failure-findings-from-the-gulf-acute-heart-failure-gulf-care-registry
#11
Charbel Abi Khalil, Kadhim Sulaiman, Rajvir Singh, Amin Jayyousi, Nidal Asaad, Khalid F AlHabib, Alawi Alsheikh-Ali, Mohammed Al-Jarallah, Bassam Bulbanat, Wael AlMahmeed, Soha Dargham, Mustafa Ridha, Nooshin Bazargani, Haitham Amin, Ahmed Al-Motarreb, Husam AlFaleh, Abdelfatah Elasfar, Prashanth Panduranga, Jassim Al Suwaidi
BACKGROUND: A U-shaped relationship has been reported between BMI and cardiovascular events among patients with acute heart failure (AHF). We hypothesized that an obesity paradox also governs the relationship between BMI and mortality in patients with type 2 diabetes (T2D) and AHF. METHODS: We studied 3-month and 12-month mortality in patients with T2D hospitalized for AHF according to 5 BMI categories: Underweight (<20kg/m(2)), normal weight (referent group, 20-24...
February 27, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28284505/clinical-characteristics-management-and-outcomes-of-patients-with-chronic-heart-failure-results-from-the-heart-function-assessment-registry-trial-in-saudi-arabia-hearts-chronic
#12
Waleed Alhabeeb, Abdelfatah Elasfar, Hanan AlBackr, Fayez AlShaer, Ali Almasood, Hussam Alfaleh, Tarek Kashour, Ahmad Hersi, Kazi Nur Asfina, Hani Altaradi, Waleed AlShaqhaa, Fakhr Alayoubi, Khalid F AlHabib
BACKGROUND: Several registries have described patients hospitalized with heart failure (HF), but only few looked at outpatients in the ambulatory setting mostly without long-term follow-up. We sought to determine the clinical characteristics, management, and 1-year outcomes of patients with chronic HF in Saudi Arabia. METHODS: Part of a prospective multicenter nationwide registry; HEart function Assessment Registry Trial in Saudi Arabia (HEARTS) and included chronic HF patients referred to four HFCs between September 2009 and December 2011...
May 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28110297/the-technical-report-on-sodium-intake-and-cardiovascular-disease-in-low-and-middle-income-countries-by-the-joint-working-group-of-the-world-heart-federation-the-european-society-of-hypertension-and-the-european-public-health-association
#13
Giuseppe Mancia, Suzanne Oparil, Paul K Whelton, Martin McKee, Anna Dominiczak, Friedrich C Luft, Khalid AlHabib, Fernando Lanas, Albertino Damasceno, Dorairaj Prabhakaran, Giuseppe La Torre, Michael Weber, Martin O'Donnell, Sidney C Smith, Jagat Narula
Ingestion of sodium is essential to health, but excess sodium intake is a risk factor for hypertension and cardiovascular disease. Defining an optimal range of sodium intake in populations has been challenging and controversial. Clinical trials evaluating the effect of sodium reduction on blood pressure have shown blood pressure lowering effects down to sodium intake of less than 1.5 g/day. Findings from these blood pressure trials form the basis for current guideline recommendations to reduce sodium intake to less than 2...
March 7, 2017: European Heart Journal
https://www.readbyqxmd.com/read/27931255/wealth-and-cardiovascular-health-a-cross-sectional-study-of-wealth-related-inequalities-in-the-awareness-treatment-and-control-of-hypertension-in-high-middle-and-low-income-countries
#14
Benjamin Palafox, Martin McKee, Dina Balabanova, Khalid F AlHabib, Alvaro Jr Avezum, Ahmad Bahonar, Noorhassim Ismail, Jephat Chifamba, Clara K Chow, Daniel J Corsi, Gilles R Dagenais, Rafael Diaz, Rajeev Gupta, Romaina Iqbal, Manmeet Kaur, Rasha Khatib, Annamarie Kruger, Iolanthe Marike Kruger, Fernando Lanas, Patricio Lopez-Jaramillo, Fu Minfan, Viswanathan Mohan, Prem K Mony, Aytekin Oguz, Lia M Palileo-Villanueva, Pablo Perel, Paul Poirier, Sumathy Rangarajan, Lei Rensheng, Annika Rosengren, Biju Soman, David Stuckler, S V Subramanian, Koon Teo, Lungiswa P Tsolekile, Andreas Wielgosz, Peng Yaguang, Karen Yeates, Mo Yongzhen, Khalid Yusoff, Rita Yusuf, Afzalhussein Yusufali, Katarzyna Zatońska, Salim Yusuf
BACKGROUND: Effective policies to control hypertension require an understanding of its distribution in the population and the barriers people face along the pathway from detection through to treatment and control. One key factor is household wealth, which may enable or limit a household's ability to access health care services and adequately control such a chronic condition. This study aims to describe the scale and patterns of wealth-related inequalities in the awareness, treatment and control of hypertension in 21 countries using baseline data from the Prospective Urban and Rural Epidemiology study...
December 8, 2016: International Journal for Equity in Health
https://www.readbyqxmd.com/read/27790819/precipitating-factors-and-90-day-outcome-of-acute-heart-failure-a-report-from-the-intercontinental-great-registry
#15
Mattia Arrigo, Etienne Gayat, Jiri Parenica, Shiro Ishihara, Jian Zhang, Dong-Ju Choi, Jin Joo Park, Khalid F Alhabib, Naoki Sato, Oscar Miro, Aldo P Maggioni, Yuhui Zhang, Jindrich Spinar, Alain Cohen-Solal, Theodore J Iwashyna, Alexandre Mebazaa
AIMS: Several clinical conditions may precipitate acute heart failure (AHF) and influence clinical outcome. In this study we hypothesized that precipitating factors are independently associated with 90-day risk of death in AHF. METHODS AND RESULTS: The study population consisted of 15 828 AHF patients from Europe and Asia. The primary outcome was 90-day all-cause mortality according to identified precipitating factors of AHF [acute coronary syndrome (ACS), infection, atrial fibrillation (AF), hypertension, and non-compliance]...
February 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/27784731/predictors-and-impact-of-in-hospital-recurrent-myocardial-infarction-in-patients-with-acute-coronary-syndrome-findings-from-gulf-race-2
#16
Abdullah S Al Saleh, Khalid F Alhabib, Alawi A Alsheik-Ali, Khadim Sulaiman, Hussam Alfaleh, Shukri Alsaif, Wael Al Mahmeed, Nidal Asaad, Haiham Amin, Ahmed Al-Motarreb, Jassim Al Suwaidi, Ahmad S Hersi
BACKGROUND: Little is known about the predictors and prognostic impact of recurrent in-hospital ischemia and infarction in patients with acute coronary syndrome (ACS). Our objectives were to determine the baseline characteristics, risk factors, and long-term outcomes of patients with recurrent myocardial infarction (Re-MI). METHODS: We evaluated patients with ACS who were enrolled in the second Gulf Registry of Acute Coronary Events from October 2008 to June 2009...
October 26, 2016: Angiology
https://www.readbyqxmd.com/read/27754306/lbos-03-01-prevalence-awareness-treatment-and-control-of-hypertension-in-the-middle-east-results-from-the-prospective-urban-rural-epidemiology-pure-study
#17
Afzalhussein Yusufali, Rasha Khatib, Shofiqul Islam, Khalid AlHabib, Roya Kelishadi, Sumathy Rangarajan, Salim Yusuf
OBJECTIVE: Data on hypertension prevalence, awareness, treatment and control are sparse in the Middle East especially in the different socio-demographic characteristics (age, sex, community location, education) and comorbid status like diabetes and cardiovascular disease. We report the prevalence, awareness, treatment, and control of hypertension across four Middle Eastern countries (Iran, Occupied Palestinian Territory (OPT), Saudi Arabia, and United Arab Emirates (UAE)), using a standardized and uniform method...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27712142/chronic-obstructive-airway-disease-among-patients-hospitalized-with-acute-heart-failure-clinical-characteristics-precipitating-factors-management-and-outcome-observational-report-from-the-middle-east
#18
Hadi A R Khafaji, Kadhim Sulaiman, Rajvir Singh, Khalid F Alhabib, Nidal Asaad, Alawi Alsheikh-Ali, Mohammed Al-Jarallah, Bassam Bulbanat, Wael Almahmeed, Mustafa Ridha, Nooshin Bazargani, Haitham Amin, Ahmed Al-Motarreb, Husam Al Faleh, Abdelfatah Elasfar, Prashanth Panduranga, Jassim Al Suwaidi
BACKGROUND: The purpose of this study was to report the prevalence, clinical characteristics, contributing factors, management and outcome of patients with chronic obstructive pulmonary disease (COPD) among patients hospitalized with heart failure (HF). METHODS: Data were derived from Gulf Care (Gulf acute heart failure registry), a prospective multicenter study of 5005 consecutive patients hospitalized with acute heart failure during February to November 2012 in seven Middle Eastern countries...
December 2015: Acute Cardiac Care
https://www.readbyqxmd.com/read/27686107/development-of-a-mobile-phone-based-intervention-to-improve-adherence-to-secondary-prevention-of-coronary-heart-disease-in-china
#19
Shu Chen, Enying Gong, Dhruv S Kazi, Ann B Gates, Kamilu Musa Karaye, Nicolas Girerd, Rong Bai, Khalid F AlHabib, Chaoyun Li, Kelly Sun, Louisa Hong, Hua Fu, Weixia Peng, Xianxia Liu, Lei Chen, J-D Schwalm, Lijing L Yan
Coronary heart disease (CHD) is a major disease burden globally and in China, but secondary prevention among CHD patients remains insufficient. Mobile health (mHealth) technology holds promise for improving secondary prevention but few previous studies included both provider-facing and patient-directed measures. We conducted a physician needs assessment survey (n = 59), physician interviews (n = 6), one focus group and a short cellphone message validation survey (n = 14) in Shanghai and Hainan, China...
October 2016: Journal of Medical Engineering & Technology
https://www.readbyqxmd.com/read/27643308/lbos-03-01-prevalence-awareness-treatment-and-control-of-hypertension-in-the-middle-east-results-from-the-prospective-urban-rural-epidemiology-pure-study
#20
Afzalhussein Yusufali, Rasha Khatib, Shofiqul Islam, Khalid AlHabib, Roya Kelishadi, Sumathy Rangarajan, Salim Yusuf
OBJECTIVE: Data on hypertension prevalence, awareness, treatment and control are sparse in the Middle East especially in the different socio-demographic characteristics (age, sex, community location, education) and comorbid status like diabetes and cardiovascular disease. We report the prevalence, awareness, treatment, and control of hypertension across four Middle Eastern countries (Iran, Occupied Palestinian Territory (OPT), Saudi Arabia, and United Arab Emirates (UAE)), using a standardized and uniform method...
September 2016: Journal of Hypertension
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