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Glasgow prognostic score

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https://www.readbyqxmd.com/read/28640776/early-fever-after-trauma-does-it-matter
#1
Holly E Hinson, Susan Rowell, Cynthia Morris, Amber L Lin, Martin A Schreiber
BACKGROUND: Fever is strongly associated with poor outcome after traumatic brain injury (TBI). We hypothesized that early fever is a direct result of brain injury and thus would be more common in TBI than in patients without brain injury, and associated with inflammation. METHODS: We prospectively enrolled patients with major trauma with and without TBI from a busy level I trauma center ICU. Patients were assigned to one of four groups based on their presenting Head Abbreviated Injury Severity Scale scores (HAIS): Polytrauma: Head AIS score >2, one other region>2, Isolated Head: Head AIS score>2, all other regions <3, Isolated Body: One region >2, excluding Head/Face, Minor Injury: No region with AIS>2...
June 20, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28625260/-predictive-value-of-four-different-scoring-systems-for-septic-patient-s-outcome-a-retrospective-analysis-with-311-patients
#2
Shengbiao Wang, Tao Li, Yunfeng Li, Jianwen Zhang, Xingui Dai
OBJECTIVE: To study the predicting value of four different scoring systems such as the acute physiology and chronic health evaluation II (APACHE II) score, sequential organ failure assessment (SOFA) score, quick SOFA (qSOFA) score and systemic inflammatory response syndrome (SIRS) score for the prognosis of septic patients. METHODS: A retrospective analysis were conducted. Septic patients in intensive care unit (ICU) of the First People's Hospital of Chenzhou form July 1st, 2012 to June 30th, 2016 were enrolled...
February 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28602178/differential-effects-of-the-glasgow-coma-scale-score-and-its-components-an-analysis-of-54-069-patients-with-traumatic-brain-injury
#3
Florence C M Reith, Hester F Lingsma, Belinda J Gabbe, Fiona E Lecky, Ian Roberts, Andrew I R Maas
INTRODUCTION: The Glasgow Coma Scale (GCS) is widely used in the assessment of clinical severity and prediction of outcome after traumatic brain injury (TBI). The sum score is frequently applied, but the differential influence of the components infrequently addressed. We aimed to investigate the contribution of the GCS components to the sum score, floor and ceiling effects of the components, and their prognostic effects. METHODS: Data on adult TBI patients were gathered from three data repositories: TARN (n=50,064), VSTR (n=14,062), and CRASH (n=9,941)...
June 1, 2017: Injury
https://www.readbyqxmd.com/read/28594285/cognitive-event-related-potentials-during-the-sub-acute-phase-of-severe-traumatic-brain-injury-and-their-relationship-to-outcome
#4
Solveig L Hauger, Kjell Olafsen, Caroline Schnakers, Nada Andelic, Kristian Bernhard Nilsen, Eirik Helseth, Ingrid Funderud, Stein Andersson, Anne-Kristine Schanke, Marianne Løvstad
Predicting outcome in the early phase after severe traumatic brain injury (sTBI) is a major clinical challenge, particularly identifying patients with potential of good cognitive outcome. The current single center prospective study aimed to explore presence and normalization of electroencephalography (EEG)-based event related potentials (ERPs) in the early phase following sTBI, and their relationship to functional and cognitive outcome 6 months post-injury. Fourteen adult patients with sTBI were recruited from the neurointensive care unit (mean age=38...
June 8, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28588769/the-glasgow-prognostic-score-useful-information-when-prescribing-palliative-radiotherapy
#5
Carsten Nieder, Bård Mannsåker, Astrid Dalhaug, Adam Pawinski, Ellinor Haukland
The purpose of the present retrospective study was to investigate whether a score reflecting systemic inflammatory processes [the Glasgow Prognostic Score (GPS)] provides relevant information for radiation oncologists. GPS is a three-tiered score [0: normal C-reactive protein (CRP) and albumin; 1: one abnormal result; 2: increased CRP and low albumin]. Correlations between disease type and extent, resource utilization, survival and GPS were analyzed in 703 patients. In the subgroup with GPS 2, significantly higher rates of lung, adrenal gland and liver metastases were observed...
June 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28566220/the-relationship-between-tumour-stage-systemic-inflammation-body-composition-and-survival-in-patients-with-colorectal-cancer
#6
Stephen T McSorley, Douglas H Black, Paul G Horgan, Donald C McMillan
BACKGROUND: Disease progression in cancer is often associated with loss of weight and lean tissue and the development of a systemic inflammatory response (SIR) and these have prognostic value. The present study investigated the relationship between these factors in patients with operable colorectal cancer. METHODS: The study included 322 patients with primary operable colorectal cancer. In addition to BMI, pre-operative CT scans were used to define the presence of visceral obesity, sarcopenia and myosteatosis...
May 19, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28551667/duration-of-preoperative-biliary-drainage-as-a-prognostic-factor-after-pancreaticoduodenectomy-for-pancreatic-head-cancer
#7
Michinori Matsumoto, Yukio Nakabayashi, Yuki Fujiwara, Naotake Funamizu, Rota Noaki, Seiichiro Eto, Hiroshi Sugano, Masahiko Otsuka, Katsuhiko Yanaga
BACKGROUND/AIM: Preoperative biliary drainage (PBD) is often performed for jaundiced patients. However, the optimal duration of PBD remains unknown. The aim of this study was to investigate whether duration of PBD influenced the prognosis of patients after pancreaticoduodenectomy (PD) for pancreatic head cancer. PATIENTS AND METHODS: Twenty-five patients who underwent PD for pancreatic head cancer with obstructive jaundice between 2007 and 2013 were included. Tumor and host factors were analyzed to evaluate their potential prognostic effects and patients' characteristics between the two groups according to the duration of PBD were analyzed...
June 2017: Anticancer Research
https://www.readbyqxmd.com/read/28539284/-c-reactive-protein-albumin-ratio-as-a-novel-inflammation-based-prognostic-index-for-predicting-outcomes-of-patients-with-colorectal-cancer
#8
Ying-Ying Chen, Jia-He Zhang, Wan Zhang, Zi-Ke Yang, Rong-Cheng Luo, Shi-Jun Kang
OBJECTIVE: To evaluate the association of C-reactive protein/albumin ratio (CAR) with the prognosis of patients with colorectal cancer and compare the prognostic value of CAR with other inflammation-based prognostic scoring systems. METHODS: We retrospectively evaluated 163 newly diagnosed colorectal cancer patients in Nanfang Hospital between January, 2007 and December, 2014. All recommended cutoff values of the clinicopathological factors were defined using receiver- operating characteristic (ROC) curve analyses...
May 20, 2017: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/28526644/simple-tumor-localization-scale-for-estimating-management-outcome-of-intracranial-meningioma
#9
Bruno Splavski, Irina Bagic, Vjenceslav Vrtaric, Brano Splavski
OBJECTIVE: Intracranial meningiomas are typically benign extracerebral tumors derived from dural arachnoid cells. Predominantly, these tumors are effectively managed surgically, but the prognosis is heavily dependent on tumors' histological heterogeneity and its location. It is known that reproductive and hormonal factors increase the risk for meningioma in adult females, but their prognostic value still remains controversial. This study's aim was to examine possible correlation between tumor location and outcome, and to evaluate prognostic value of the proposed simple tumor localization scale in predicting the management outcome of intracranial meningioma...
May 16, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28515920/predictive-value-of-the-modified-glasgow-prognostic-score-for-the-therapeutic-effects-of-molecular-targeted-drugs-on-advanced-renal-cell-carcinoma
#10
Hirofumi Ohmura, Keita Uchino, Tatsuhiro Kajitani, Naotaka Sakamoto, Eishi Baba
Inflammation is considered to be a prognostic factor for renal cell carcinoma (RCC). An inflammation-based prognostic score (modified Glasgow Prognostic Score; mGPS) is widely used for preoperative patients; however, little information is available regarding its prognostic value in patients with RCC treated with molecular-targeted drugs. A total of 32 advanced and recurrent RCC patients initially treated with molecular-targeted drugs from October, 2009 to August, 2015 were retrospectively investigated. Information on patient characteristics prior to treatment initiation and the clinical course were retrieved from clinical records...
May 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28497927/the-potential-role-of-pain-related-sseps-in-the-early-prognostication-of-long-term-functional-outcome-in-post-anoxic-coma
#11
Alessandra Del Felice, Stefano Bargellesi, Federico Linassi, Bruno Scarpa, Emanuela Formaggio, Paolo Boldrini, Stefano Masiero, Paolo Zanatta
BACKGROUND: Cardiac arrest (CA) is a common cause of disability. Multimodal evaluation has improved prognosis but precocious biomarkers are not appropriate in determining long-term functional outcome. AIM: to identify early prognostication markers of long-term functional outcome in post-anoxic coma. DESIGN: retrospective assessment of outcomes. POPULATION: Individuals older than 18 years with post-anoxic coma hospitalized in intensive care units after cardiac arrest (CA) regardless of cause (cardiac or non-cardiac) and location of event (in or out-of-hospital)...
May 12, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28492412/patients-in-prehospital-transport-to-the-emergency-department-a-cohort-study-of-risk-factors-for-7-day-mortality
#12
Camilla L Noergaard Bech, Mikkel Brabrand, Søren Mikkelsen, Annmarie Lassen
BACKGROUND: Ambulance transfer is the first contact with the healthcare system for many patients in emergency conditions.We aimed to identify prognostic risk factors accessible in the prehospital phase that indicate an increased risk of 7-day mortality. PATIENTS AND METHODS: We included patients aged 18 years or older, transferred by ambulance to the emergency department at Odense University Hospital, from 1 April 2012 to 30 September 2014. We carried out multivariate logistic regressions, adjusted for age and sex, to describe the relationship between vital sign values recorded in the prehospital setting and 7-day mortality...
May 10, 2017: European Journal of Emergency Medicine: Official Journal of the European Society for Emergency Medicine
https://www.readbyqxmd.com/read/28486893/relationship-between-functional-status-prior-to-onset-of-critical-illness-and-mortality-a-prospective-multicentre-cohort-study
#13
R Rivera-Lopez, R Gutierrez-Rodriguez, C Lopez-Caler, E Aguilar-Alonso, E Castillo-Lorente, M Garcia-Delgado, M D Arias-Verdu, D Iglesias-Posadilla, J E Barrueco-Francioni, G Quesada-Garcia, R Rivera-Fernandez
This prospective study aimed to assess the association between prior functional status and hospital mortality for patients admitted to four intensive care units in Spain between 2006 and 2012. Prior functional status was classified into three groups, using a modification of the Glasgow Outcome Scale (GOS), including group 1 with no limitations on activities of daily living; group 2 with some limitations but self-sufficient; and group 3 who were dependent on others for their activities of daily living. Of the 1,757 patients considered (mean Simplified Acute Physiology Score [SAPS] predicted mortality 14...
May 2017: Anaesthesia and Intensive Care
https://www.readbyqxmd.com/read/28483664/significance-of-the-glasgow-prognostic-score-for-patients-with-colorectal-liver-metastasis
#14
Sho Okimoto, Tsuyoshi Kobayashi, Hirotaka Tashiro, Shintaro Kuroda, Kohei Ishiyama, Kentaro Ide, Tomoyuki Abe, Masakazu Hashimoto, Hiroshi Iwako, Michinori Hamaoka, Naruhiko Honmyo, Megumi Yamaguchi, Hideki Ohdan
BACKGROUND: Systemic inflammation and nutritional status are strongly associated with tumor progression. Inflammation-based prognostic scores, such as the Glasgow Prognostic Score (GPS), reflect these states and are predictive in patients with several types of advanced cancers. The aim of this study was to evaluate the significance of GPS in patients with colorectal liver metastasis (CRLM). PATIENTS AND METHODS: Study subjects were 134 patients with CRLM who underwent initial radical liver resection at Hiroshima University Hospital between January 2000 and December 2013...
June 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28467584/the-geriatric-polytrauma-risk-profile-and-prognostic-factors
#15
Holger Rupprecht, Hans Jürgen Heppner, Kristina Wohlfart, Alp Türkoglu
BACKGROUND: In the German population, the percentage of elderly patients is increasing, and consequently there are more elderly patients among trauma cases, and particularly cases of polytrauma. The aim of this study was to present clinical results and a risk profile for geriatric polytrauma patients. METHODS: Review of 140 geriatric (over 65 years of age) polytrauma patients who received prehospital treatment was performed. Severity of trauma was retrospectively assessed with Hannover Polytrauma Score (HPTS)...
March 2017: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/28466149/potentially-modifiable-factors-contributing-to-sepsis-associated-encephalopathy
#16
Romain Sonneville, Etienne de Montmollin, Julien Poujade, Maïté Garrouste-Orgeas, Bertrand Souweine, Michael Darmon, Eric Mariotte, Laurent Argaud, François Barbier, Dany Goldgran-Toledano, Guillaume Marcotte, Anne-Sylvie Dumenil, Samir Jamali, Guillaume Lacave, Stéphane Ruckly, Bruno Mourvillier, Jean-François Timsit
PURPOSE: Identifying modifiable factors for sepsis-associated encephalopathy may help improve patient care and outcomes. METHODS: We conducted a retrospective analysis of a prospective multicenter database. Sepsis-associated encephalopathy (SAE) was defined by a score on the Glasgow coma scale (GCS) <15 or when features of delirium were noted. Potentially modifiable risk factors for SAE at ICU admission and its impact on mortality were investigated using multivariate logistic regression analysis and Cox proportional hazard modeling, respectively...
May 2, 2017: Intensive Care Medicine
https://www.readbyqxmd.com/read/28459061/patients-admitted-to-three-spanish-intensive-care-units-for-poisoning-type-of-poisoning-mortality-and-functioning-of-prognostic-scores-commonly-used
#17
María Esther Banderas-Bravo, Maria Dolores Arias-Verdú, Ines Macías-Guarasa, Eduardo Aguilar-Alonso, Encarnación Castillo-Lorente, Lucia Pérez-Costillas, Raquel Gutierrez-Rodriguez, Guillermo Quesada-García, Ricardo Rivera-Fernández
Objectives. To evaluate the gravity and mortality of those patients admitted to the intensive care unit for poisoning. Also, the applicability and predicted capacity of prognostic scales most frequently used in ICU must be evaluated. Methods. Multicentre study between 2008 and 2013 on all patients admitted for poisoning. Results. The results are from 119 patients. The causes of poisoning were medication, 92 patients (77.3%), caustics, 11 (9.2%), and alcohol, 20 (16,8%). 78.3% attempted suicides. Mean age was 44...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28455815/perfusion-abnormalities-are-frequently-detected-by-early-ct-perfusion-and-predict-unfavourable-outcome-following-severe-traumatic-brain-injury
#18
Cino Bendinelli, Shannon Cooper, Tiffany Evans, Andrew Bivard, Dianne Pacey, Mark Parson, Zsolt J Balogh
BACKGROUND: In patients with severe traumatic brain injury (TBI), early CT perfusion (CTP) provides additional information beyond the non-contrast CT (NCCT) and may alter clinical management. We hypothesized that this information may prognosticate functional outcome. METHODS: Five-year prospective observational study was performed in a level-1 trauma centre on consecutive severe TBI patients. CTP (obtained in conjunction with first routine NCCT) was interpreted as: abnormal, area of altered perfusion more extensive than on NCCT, and the presence of ischaemia...
April 28, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28447170/surgery-or-stereotactic-body-radiotherapy-for-elderly-stage-i-lung-cancer-a-propensity-score-matching-analysis
#19
Takuro Miyazaki, Takuya Yamazaki, Daisuke Nakamura, Shuntaro Sato, Naoya Yamasaki, Tomoshi Tsuchiya, Keitaro Matsumoto, Ryotaro Kamohara, Go Hatachi, Takeshi Nagayasu
PURPOSE: The aim of this study was to compare the outcomes of surgery and stereotactic body radiotherapy (SBRT) for elderly clinical stage I non-small cell lung cancer (NSCLC) patients. METHODS: Patients ≥80 years of age with clinical stage I NSCLC between August 2008 and December 2014 were treated either surgery or SBRT. Propensity score matching was performed to reduce bias in various clinicopathological factors. RESULTS: Surgery was performed in 57 cases and SBRT in 41 cases...
April 26, 2017: Surgery Today
https://www.readbyqxmd.com/read/28443058/predicting-outcome-12-months-after-mild-traumatic-brain-injury-in-patients-admitted-to-a-neurosurgery-service
#20
Torgeir Hellstrøm, Tobias Kaufmann, Nada Andelic, Helene L Soberg, Solrun Sigurdardottir, Eirik Helseth, Ole A Andreassen, Lars T Westlye
OBJECTIVE: Accurate outcome prediction models for patients with mild traumatic brain injury (MTBI) are key for prognostic assessment and clinical decision-making. Using multivariate machine learning, we tested the unique and added predictive value of (1) magnetic resonance imaging (MRI)-based brain morphometric and volumetric characterization at 4-week postinjury and (2) demographic, preinjury, injury-related, and postinjury variables on 12-month outcomes, including global functioning level, postconcussion symptoms, and mental health in patients with MTBI...
2017: Frontiers in Neurology
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