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Glasgow prognostic score

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https://www.readbyqxmd.com/read/28062344/prognostic-tools-in-patients-with-advanced-cancer-a-systematic-review
#1
REVIEW
Claribel P L Simmons, Donald C McMillan, Kerry McWilliams, Tonje A Sande, Kenneth C Fearon, Sharon Tuck, Marie T Fallon, Barry J Laird
PURPOSE: In 2005, the European Association for Palliative Care (EAPC) made recommendations for prognostic markers in advanced cancer. Since then, prognostic tools have been developed, evolved and validated. The aim of this systematic review was to examine the progress in the development and validation of prognostic tools. METHODS: Medline, Embase Classic + and Embase were searched. Eligible studies met the following criteria: patients with incurable cancer; >18 years; original studies; population n>100; published after 2003...
January 3, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28059838/comparison-of-the-prognostic-significance-of-initial-blood-lactate-and-base-deficit-in-trauma-patients
#2
Mathieu Raux, Yannick Le Manach, Tobias Gauss, Romain Baumgarten, Sophie Hamada, Anatole Harrois, Bruno Riou, Jacques Duranteau, Olivier Langeron, Jean Mantz, Catherine Paugam-Burtz, Bernard Vigue
BACKGROUND: Initial blood lactate and base deficit have been shown to be prognostic biomarkers in trauma, but their respective performances have not been compared. METHODS: Blood lactate levels and base deficit were measured at admission in trauma patients in three level 1 trauma centers. This was a retrospective analysis of prospectively acquired data. The association of initial blood lactate and base deficit with mortality was tested using receiver operating characteristics curve, logistic regression using triage scores (Revised Trauma Score and Mechanism Glasgow scale and Arterial Pressure score), and Trauma Related Injury Severity Score as a reference standard...
January 6, 2017: Anesthesiology
https://www.readbyqxmd.com/read/28058140/predictive-value-of-brain-arrest-neurological-outcome-scale-branos-on-mortality-and-morbidity-after-cardiac-arrest
#3
Cengiz Şahutoğlu, Mehmet Uyar, Kubilay Demirağ, Hasan İsayev, Ali Reşat Moral
OBJECTIVE: There are several prediction scales and parameters for prognosis after a cardiac arrest. One of these scales is the brain arrest neurological outcome scale (BrANOS), which consists of duration of cardiac arrest, Glasgow Coma Scale score and Hounsfield unit measured on cranial computed tomography (CT) scan. The objective of this study is to investigate the effectiveness of BrANOS on predicting the mortality and disability after a cardiac arrest. METHODS: We retrospectively investigated cardiac arrest patients who were hospitalized in our intensive care unit (ICU) within a 3-year period...
December 2016: Turkish Journal of Anaesthesiology and Reanimation
https://www.readbyqxmd.com/read/28049261/nutrition-assessment-and-its-relationship-with-performance-and-glasgow-prognostic-scores-in-vietnamese-patients-with-esophageal-cancer
#4
Tran Chau Quyen, Jongjit Angkatavanich, Tran Van Thuan, Vo Van Xuan, Le Danh Tuyen, Do Anh Tu
BACKGROUND AND OBJECTIVES: To determine the nutritional status of patients with esophageal cancer, and to investigate its relationship with performance status and prognosis. METHODS AND STUDY DESIGN: This clinical, cross-sectional study was conducted from August 2014 to February 2015 at National Cancer Hospital, Hanoi, Vietnam. Stage III/IV esophageal cancer patients were assessed for their nutritional status (patient-generated subjective global assessment (PG-SGA) and SGA scores, BMI, mid-arm circumference (MAC), energy and protein intakes, weight changes, Karnofsky and Eastern cooperative oncology group performance scores (KPS/ECOG), and Glasgow prognostic score (GPS)...
January 2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28049196/refining-prognosis-for-intracerebral-hemorrhage-by-early-reassessment
#5
Matthew B Maas, Brandon A Francis, Rajbeer S Sangha, Bryan D Lizza, Eric M Liotta, Andrew M Naidech
BACKGROUND: Prognostic assessments, which are crucial for decision-making in critical illnesses, have shown unsatisfactory reliability. We compared the accuracy of a widely used prognostic score against a model derived from clinical data obtained 5 days after admission for patients with intracerebral hemorrhage (ICH), a condition for which prognostication has proven notoriously challenging and prone to bias. METHODS: Patients enrolled in a prospective observational cohort study of spontaneous ICH underwent hourly Glasgow Coma Scale (GCS) assessment...
January 4, 2017: Cerebrovascular Diseases
https://www.readbyqxmd.com/read/28031096/impact-of-intraoperative-blood-pressure-control-and-temporary-parent-artery-blocking-on-prognosis-in-cerebral-aneurysms-surgery
#6
Min Xu, Zheng-Song Gu, Cun-Zu Wang, Xiao-Feng Lu, Ding-Chao Xiang, Zhi-Cheng Yuan, Qiao-Yu Li, Min Wu
Objective In cerebral aneurysm clipping and embolization, blood pressure control and temporary parent artery blocking are common methods to prevent aneurysm rupture. Their influence on the prognosis is uncertain. In this study, we try to find out the association between methods above and prognostic indicators.Methods We held a retrospective analysis on patients' medical records of cerebral aneurysms surgical clipping and endovascular coiling , and recorded gender, age, diagnosis, Hunt-Hess grade, Glasgow coma scale score, treatment methods, a history of hypertension, preoperative systolic blood pressure, with or without controlled hypotension, systolic blood pressure difference before and after controlled hypotension, with or without temporary artery blocking, with or without hypertension after treated aneurysm, prognostic indicators including mortality after 1 month, intensive care unit (ICU) stay time of survivors, discharged Glasgow outcome scale (GOS) score...
June 20, 2016: Chinese Medical Sciences Journal, Chung-kuo i Hsüeh K'o Hsüeh Tsa Chih
https://www.readbyqxmd.com/read/28011279/association-of-prophylactic-endotracheal-intubation-in-critically-ill-patients-with-upper-gi-bleeding-and-cardiopulmonary-unplanned-events
#7
Umar Hayat, Peter J Lee, Hamid Ullah, Shashank Sarvepalli, Rocio Lopez, John J Vargo
BACKGROUND: Prophylactic endotracheal intubation (PEI) is often advocated to mitigate the risk of cardiopulmonary adverse events in patients presenting with brisk upper gastrointestinal bleed (UGIB). However, the benefit of such a measure remains controversial. Our study aimed to compare the incidence of cardiopulmonary unplanned events (CUE) between patients who underwent endotracheal intubation versus those who didn't, in critically ill patients with brisk UGIB. METHODS: Patients aged 18 years or older who had presented at Cleveland Clinic between 2011 and 2014 with hematemesis and/or patients with melena with consequential hypovolemic shock were included...
December 20, 2016: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28008988/prognostic-value-of-inflammation-based-scores-in-patients-with-osteosarcoma
#8
Bangjian Liu, Yujing Huang, Yuanjue Sun, Jianjun Zhang, Yang Yao, Zan Shen, Dongxi Xiang, Aina He
Systemic inflammation responses have been associated with cancer development and progression. C-reactive protein (CRP), Glasgow prognostic score (GPS), neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), lymphocyte-monocyte ratio (LMR), and neutrophil-platelet score (NPS) have been shown to be independent risk factors in various types of malignant tumors. This retrospective analysis of 162 osteosarcoma cases was performed to estimate their predictive value of survival in osteosarcoma. All statistical analyses were performed by SPSS statistical software...
December 23, 2016: Scientific Reports
https://www.readbyqxmd.com/read/28007738/malondialdehyde-as-a-prognostic-factor-in-alcoholic-hepatitis
#9
Onán Pérez-Hernández, Emilio González-Reimers, Geraldine Quintero-Platt, Pedro Abreu-González, María José de la Vega-Prieto, María José Sánchez-Pérez, Candelaria Martín-González, Antonio Martínez-Riera, Francisco Santolaria-Fernández
AIMS: Alcoholic hepatitis is a severe complication of alcoholism, associated with high short-term mortality. Although pathogenesis remains obscure, it is generally accepted that lipopolysaccharide-induced cytokine secretion with further generation of reactive oxygen species (ROS) play outstanding roles. Prognosis is uncertain, and the usually employed prognostic scores do not include variables related to ROS generation.Therefore, this study was performed to assess short-term prognostic value of cytokines, nutritional status, different scores [Maddrey, model for end-stage liver disease (MELD), albumin, bilirubin, INR, creatinine index (ABIC), Lille, Glasgow, MELD-Na, Child-Pugh] and malondialdehyde (MDA, as an indicator of lipid peroxidation) at admission and after 1 week, among patients affected by severe acute alcoholic hepatitis (Maddrey index >32)...
December 21, 2016: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28001023/modified-glasgow-prognostic-score-might-be-a-prognostic-factor-for-hepatocellular-carcinoma-a-meta-analysis
#10
Hong Chen, Nan Hu, Peng Chang, Tao Kang, Song Han, Yaoliang Lu, Maoquan Li
INTRODUCTION: Hepatocellular carcinoma (HCC) is the fifth-most common cancer. Recent studies have demonstrated that there was a relationship between modified Glasgow prognostic score (mGPS) and survival of HCC. However, the results were inconsistent. EVIDENCE ACQUISITION: The following databases were searched for relevant articles published up until June 2016: PubMed; EMBASE; Web of Science and the China National Knowledge Infrastructure. The strength of association between mGPS and OS of HCC was estimated by pooled HRs with corresponding 95% CIs...
December 21, 2016: Panminerva Medica
https://www.readbyqxmd.com/read/27984403/the-glasgow-prognostic-score-at-the-time-of-palliative-esophageal-stent-insertion-is-a-predictive-factor-of-30-day-mortality-and-overall-survival
#11
Robert J Driver, Catherine Handforth, Ganesh Radhakrishna, Michael I Bennett, Alexander C Ford, Simon M Everett
BACKGROUND: Optimizing the timing of esophageal stent insertion is a challenge, partly due to difficulty predicting survival in advanced malignancy. The Glasgow prognostic score (GPS) is a validated tool for predicting survival in a number of cancers. GOALS: To assess the utility of the GPS in predicting 30-day mortality and overall survival postesophageal stent insertion. STUDY: Patients at a tertiary referral center who had received an esophageal stent for palliation of dysphagia were included if they had a measurement of albumin and C-reactive protein (CRP) in the week preceding the procedure (n=209)...
December 14, 2016: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/27984214/comparison-of-preoperative-inflammation-based-prognostic-scores-in-patients-with-colorectal-cancer
#12
Yoshiyuki Suzuki, Koji Okabayashi, Hirotoshi Hasegawa, Masashi Tsuruta, Kohei Shigeta, Takayuki Kondo, Yuko Kitagawa
OBJECTIVE: To evaluate the prognostic impact of the systemic inflammation score (SIS) in colorectal cancer (CRC) patients in comparison with a conventional inflammation-based score, the modified Glasgow Prognostic Score (mGPS). SUMMARY BACKGROUND DATA: The SIS, which is calculated based on the preoperative serum albumin level and lymphocyte-to-monocyte ratio, is a reported prognostic marker in clear-cell renal cell carcinoma. However, the utility of the SIS in CRC remains unclear...
December 15, 2016: Annals of Surgery
https://www.readbyqxmd.com/read/27975043/predictive-value-of-neuron-specific-enolase-for-prognosis-in-patients-with-moderate-or-severe-traumatic-brain-injury-a-systematic-review-and-meta-analysis
#13
Eric Mercier, Amélie Boutin, Michèle Shemilt, François Lauzier, Ryan Zarychanski, Dean A Fergusson, Lynne Moore, Lauralyn A McIntyre, Patrick Archambault, France Légaré, François Rousseau, François Lamontagne, Linda Nadeau, Alexis F Turgeon
BACKGROUND: Prognosis is difficult to establish early after moderate or severe traumatic brain injury despite representing an important concern for patients, families and medical teams. Biomarkers, such as neuron-specific enolase, have been proposed as potential early prognostic indicators. Our objective was to determine the association between neuron-specific enolase and clinical outcomes, and the prognostic value of neuron-specific enolase after a moderate or severe traumatic brain injury...
July 2016: CMAJ Open
https://www.readbyqxmd.com/read/27966313/neurological-outcome-after-cardiac-arrest-a-prospective-study-of-the-predictive-ability-of-prognostic-biomarkers-neuron-specific-enolase-glial-fibrillary-acidic-protein-s-100b-and-procalcitonin
#14
Gülay Ok, Demet Aydın, Koray Erbüyün, Canan Gürsoy, Fatma Taneli, Sema Bilge, Gönül Dinç Horasan
BACKGROUND/AIM: Factors affecting neurological outcome and the usefulness of neuron-specific enolase (NSE), S-100B, glial fibrillary acidic protein (GFAP), and procalcitonin (PCT) in predicting neurological outcomes were assessed in patients who survived at least 24 h after cardiopulmonary resuscitation (CPR). MATERIALS AND METHODS: Thirty successfully resuscitated cardiac arrest patients were included in this prospective clinical study. The initial cardiac arrest rhythm, duration of CPR, return of spontaneous circulation time, administered doses of adrenaline, base excess, blood sugar, and hemodynamic parameters were recorded...
November 17, 2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/27965920/blunt-traumatic-cardiac-rupture-single-institution-experiences-over-14-years
#15
Jeong Hee Yun, Joung Hun Byun, Sung Hwan Kim, Sung Ho Moon, Hyun Oh Park, Sang Won Hwang, Yong Hwan Kim
BACKGROUND: Blunt traumatic cardiac rupture is rare. However, such cardiac ruptures carry a high mortality rate. This study reviews our experience treating blunt traumatic cardiac rupture. METHODS: This retrospective study included 21 patients who experienced blunt traumatic cardiac rupture from 1999 to 2015. Every patient underwent surgery. Several variables were compared between survivors and fatalities. RESULTS: Sixteen of the 21 patients survived, and 5 (24%) died...
December 2016: Korean Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27943355/serum-level-of-cxcl10-is-associated-with-inflammatory-prognostic-biomarkers-in-patients-with-diffuse-large-b-cell-lymphoma
#16
Jung Yong Hong, Kyung Ju Ryu, Ji Yean Lee, Chaehwa Park, Young Hyeh Ko, Won Seog Kim, Seok Jin Kim
Inflammatory biomarkers, such as the neutrophil to lymphocyte ratio (NLR), lymphocyte to monocyte ratio (LMR), and Glasgow Prognostic Score (GPS) have been proposed to predict prognosis in diffuse large B-cell lymphoma (DLBCL). C-X-C motif ligand 10 (CXCL10) is a chemokine released from inflammatory cells in the tumor microenvironment and is known to promote tumor cell migration and invasion. In this study, we investigated the clinical impact of pretreatment serum level of CXCL10 on the prognostic value of inflammatory biomarkers in 313 patients with DLBCL who were enrolled into a prospective cohort study...
December 12, 2016: Hematological Oncology
https://www.readbyqxmd.com/read/27930703/the-c-reactive-protein-to-albumin-ratio-as-a-predictor-of-severe-side-effects-of-adjuvant-chemotherapy-in-stage-iii-colorectal-cancer-patients
#17
Tetsuro Tominaga, Takashi Nonaka, Yorihisa Sumida, Shigekazu Hidaka, Terumitsu Sawai, Takeshi Nagayasu
BACKGROUND/AIMS: Adjuvant chemotherapy (AC) has been reported to improve the prognosis for patients with Stage III colorectal cancer (CRC). However, some patients experience severe side effects and must stop AC. The C-reactive protein (CRP) to albumin ratio (CAR) is a novel inflammation-based score that could reflect the patient's general condition. The aim of this study was to evaluate the predictive value of the CAR for side effects of AC in CRC. METHODS: A total of 136 CRC patients who received AC were retrospectively analyzed...
2016: PloS One
https://www.readbyqxmd.com/read/27920003/clinical-significance-of-the-glasgow-prognostic-score-in-patients-with-gastrointestinal-stromal-tumors
#18
Takaaki Arigami, Yoshikazu Uenosono, Sumiya Ishigami, Shigehiro Yanagita, Keishi Okubo, Yasuto Uchikado, Yoshiaki Kita, Shinichiro Mori, Hiroshi Kurahara, Kosei Maemura, Shoji Natsugoe
AIM: To assess the clinical utility of the Glasgow prognostic score (GPS) as a blood predictor of postoperative recurrence in patients with gastric gastrointestinal stromal tumors (GISTs). PATIENTS AND METHODS: Twenty-nine patients with gastric GISTs undergoing gastrectomy were retrospectively reviewed. Patients were classified based on GPS criteria as follows: GPS of 2: elevated C-reactive protein (>1.0 mg/dl) and hypoalbuminemia (<3.5 g/dl), GPS of 1: one of these hematological abnormalities, and GPS of 0: neither elevated CRP nor hypoalbuminemia...
2016: Anticancer Research
https://www.readbyqxmd.com/read/27917647/admission-neutrophil-count-and-neutrophil-to-lymphocyte-ratio-predict-90-day-outcome-in-intracerebral-hemorrhage
#19
Chuanyuan Tao, Xin Hu, Jiajing Wang, Junpeng Ma, Hao Li, Chao You
AIM: Inflammation plays a role in secondary brain injury after intracerebral hemorrhage (ICH). We aimed to determine the prognostic significance of admission white blood cell (AWC), neutrophil count (ANC), lymphocyte count, monocyte count and neutrophil to lymphocyte ratio (NLR) for 90-day outcome after ICH. PATIENTS & METHODS: A total of 336 patients with spontaneous ICH were retrospectively investigated. Clinical outcome was assessed by modified Rankin Scale at 90 days...
January 2017: Biomarkers in Medicine
https://www.readbyqxmd.com/read/27895358/paediatric-traumatic-brain-injury-presentation-prognostic-indicators-and-outcome-analysis-from-a-tertiary-care-center-in-a-developing-country
#20
Badar Ujjan, Muhammad Waqas, Muhammad Babar Khan, Saqib Kamran Bakhshi, Muhammad Ehsan Bari
Traumatic brain injury (TBI) is the leading cause of morbidity and mortality in children worldwide. This study was conducted to report the presentation, management, outcomes and prognostic indicators in a large series of patients from a tertiary care centre in a developing country. It is a review of prospectively collected data of paediatric patients with TBI admitted at our centre between July 2010 and December 2013. A total of 291 patients with a mean age of 7.2±5.0 years were dichotomised into survivors and non-survivors, and variables were compared between the two groups...
October 2016: JPMA. the Journal of the Pakistan Medical Association
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