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https://www.readbyqxmd.com/read/28823122/genetic-analysis-of-milk-production-traits-of-tunisian-holsteins-using-random-regression-test-day-model-with-legendre-polynomials
#1
Hafedh Ben Zaabza, Abderrahmen Ben Gara, Boulbaba Rekik
Objective: The objective of this study was to estimate genetic parameters of milk, fat, and protein yields within and across lactations in Tunisian Holsteins using a random regression test-day model. Methods: A random regression multiple trait multiple lactation test-day (TD) model was used to estimate genetic parameters in the Tunisian dairy cattle population. Data were TD yields of milk, fat, and protein from the first three lactations. Random regressions were modeled with third-order Legendre polynomials for the additive genetic, and permanent environment effects...
August 16, 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28822806/pericardial-adipose-and-aromatase-a-new-translational-target-for-aging-obesity-and-arrhythmogenesis
#2
Gabriel B Bernasochi, Wah Chin Boon, Claire L Curl, Upasna Varma, Salvatore Pepe, Marianne Tare, Laura J Parry, Evdokia Dimitriadis, Stephen B Harrap, Chrishan J Nalliah, Jonathan M Kalman, Lea M D Delbridge, James R Bell
A correlation exists between the extent of pericardial adipose and atrial fibrillation (AF) risk, though the underlying mechanisms remain unclear. Selected adipose depots express high levels of aromatase, capable of converting androgens to estrogens - no studies have investigated aromatase occurrence/expression regulation in pericardial adipose. The Women's Health Initiative reported that estrogen-only therapy in women elevated AF incidence, indicating augmented estrogenic influence may exacerbate cardiac vulnerability...
August 16, 2017: Journal of Molecular and Cellular Cardiology
https://www.readbyqxmd.com/read/28822761/down-regulation-of-vascular-ppar-%C3%AE-contributes-to-endothelial-dysfunction-in-high-fat-diet-induced-obese-mice-exposed-to-chronic-intermittent-hypoxia
#3
Yanan Zhang, Chunlian Zhang, Haiou Li, Jingdong Hou
Obstructive sleep apnea (OSA), characterized by chronic intermittent hypoxia (CIH), is associated with endothelial dysfunction. The prevalence of OSA is linked to an epidemic of obesity. CIH has recently been reported to cause endothelial dysfunction in diet-induced obese animals by exaggerating oxidative stress and inflammation, but the underlying mechanism remains unclear. PPAR-γ, a ligand-inducible transcription factor that exerts anti-oxidant and anti-inflammatory effects, is down-regulated in the peripheral tissues in diet-induce obesity...
August 16, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28822545/effects-of-the-dose-and-viability-of-saccharomyces-cerevisiae-2-ruminal-fermentation-performance-of-lactating-dairy-cows-and-correlations-between-ruminal-bacteria-abundance-and-performance-measures
#4
Y Jiang, I M Ogunade, K G Arriola, M Qi, D Vyas, C R Staples, A T Adesogan
This study examined effects of the dose and viability of supplemented Saccharomyces cerevisiae yeast strain YE1496 on ruminal fermentation and performance of lactating dairy cows. A second objective was to examine correlations between ruminal bacteria abundance and performance measures. Four ruminally cannulated lactating cows (284 ± 18 days in milk) were assigned randomly to 1 of 4 treatment sequences in a 4 × 4 Latin square experimental design using four 21-d experimental periods. Cows were fed a nonacidotic total mixed ration comprising 22...
August 16, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28822544/performance-strategies-affect-mammary-gland-development-in-prepubertal-heifers
#5
R L Albino, A L Sguizzato, K M Daniels, M S Duarte, M M Lopes, S E F Guimarães, M M D C A Weller, M I Marcondes
In Brazil, the majority of dairy cattle are Holstein × Gyr (H×G). It is unknown whether excessive energy intake negatively affects their mammary development to the same extent as in purebred Holsteins. We hypothesized that mammary development of H×G heifers can be affected by dietary energy supply. We evaluated the effect of different average daily gains (ADG) achieved by feeding different amounts of a standard diet during the growing period on biometric measurements, development of mammary parenchyma (PAR) and mammary fat pad (MFP), and blood hormones...
August 16, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28822209/primary-culture-of-rat-aortic-vascular-smooth-muscle-cells-a-new-method
#6
Jufang Chi, Liping Meng, Sunlei Pan, Hui Lin, Xiaoya Zhai, Longbin Liu, Changzuan Zhou, Chengjian Jiang, Hangyuan Guo
BACKGROUND Developing a simple and efficient method of obtaining primary cultured VSMCs is necessary for basic cardiovascular research. MATERIAL AND METHODS The procedure of our new method mainly includes 6 steps: isolation of the aortic artery, removal of the fat tissue around the artery, separation of the media, cutting the media into small tissue blocks, transferring the tissue blocks to cell culture plates, and incubation until the cells reach confluence. The cells were identified as VSMCs by morphology and immunofluorescence...
August 19, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28821567/chronic-spinal-cord-changes-in-a-high-fat-diet-fed-male-rat-model-of-thoracic-spinal-contusion
#7
Redin A Spann, William J Lawson, Raymond J Grill, Michael R Garrett, Bernadette E Grayson
Individuals that suffer injury to the spinal cord can result in long-term, debilitating sequelae. Spinal cord injured patients have increased risk for the development of metabolic disease which can further hinder the effectiveness of treatments to rehabilitate the cord and improve quality of life. In the present study, we sought to understand the impact of high-fat diet induced obesity on spinal cord injury (SCI) by examining transcriptome changes in the area of the injury and rostral and caudal to site of damage 12 weeks after injury...
August 18, 2017: Physiological Genomics
https://www.readbyqxmd.com/read/28821417/single-species-versus-dual-species-probiotic-supplementation-as-an-emerging-therapeutic-strategy-for-obesity
#8
G Karimi, R Jamaluddin, N Mohtarrudin, Z Ahmad, H Khazaai, M Parvaneh
BACKGROUND AND AIM: Recent studies have reported beneficial effects of specific probiotics on obesity. However, the difference in the anti-obesity effects of probiotics as single species and dual species is still uncertain. Therefore, we aimed to compare the efficacy of single and dual species of bacteria on markers of obesity in high-fat diet-induced obese rats. METHODS AND RESULTS: A total of 40 male Sprague-Dawley rats were assigned to one of five groups of varying diets as follows: standard diet, high fat diet (HFD), HFD supplemented with Lactobacillus casei strain Shirota, HFD supplemented with Bifidobacterium longum and HFD supplemented with a mixture of these two bacterial species...
July 8, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/28821318/consumption-of-an-acid-protease-derived-from-aspergillus-oryzae-causes-bifidogenic-effect-in-rats
#9
Yongshou Yang, Akane Iwamoto, Thanutchaporn Kumrungsee, Yukako Okazaki, Manabu Kuroda, Shotaro Yamaguchi, Norihisa Kato
A marked elevation in the abundance of Bifidobacterium was found in the cecum of rats that were fed a high-fat diet supplemented with an Amano protease preparation (derived from Aspergillus oryzae). The protease preparation contains several digestive enzymes, including acid protease (AcP), alkaline protease, and amylase. We hypothesized that the elevation in the abundance of Bifidobacterium by Amano protease preparation is associated with the digestive enzymes involved in the protease preparation. To test this hypothesis, this study was conducted to investigate if such bifidogenic effect is because of the AcP...
August 2017: Nutrition Research
https://www.readbyqxmd.com/read/28821314/intraventricular-administration-of-tenebrio-molitor-larvae-extract-regulates-food-intake-and-body-weight-in-mice-with-high-fat-diet-induced-obesity
#10
Minchul Seo, Jongwan Kim, Seong-Su Moon, Jae-Sam Hwang, Mi-Ae Kim
We recently reported the in vitro and in vivo antiobesity effects of Tenebrio molitor larvae, a traditional food in many countries, but it remains unknown how the larvae affect appetite regulation in mice with diet-induced obesity. We hypothesized that the extract of T molitor larvae mediates appetite by regulating neuropeptide expression. We investigated T molitor larvae extract's (TME's) effects on anorexigenesis and endoplasmic reticulum (ER) stress-induced orexigenic neuropeptide expression in the hypothalami of obese mice...
August 2017: Nutrition Research
https://www.readbyqxmd.com/read/28821313/the-influence-of-the-position-of-palmitate-in-infant-formula-triacylglycerols-on-health-outcomes
#11
REVIEW
Elizabeth A Miles, Philip C Calder
The purpose of this review is to discuss recent studies reporting on the influence of the position of palmitic acid in triacylglycerols in infant formula and relevant animal studies. Earlier experiments in rodents show that a diet with a higher proportion of palmitate at the sn-2 position of triacylglycerols improves dietary fat and calcium absorption compared with a diet with a lower sn-2 palmitate content. A high-sn-2 palmitate diet increased fecal short-chain fatty acids, reduced gut inflammation in a colitis model, and altered tissue endocannabinoid concentrations in laboratory rodents...
August 2017: Nutrition Research
https://www.readbyqxmd.com/read/28820912/impact-of-novel-palmitoylated-prolactin-releasing-peptide-analogs-on-metabolic-changes-in-mice-with-diet-induced-obesity
#12
Veronika Pražienková, Martina Holubová, Helena Pelantová, Martina Bugáňová, Zdenko Pirník, Barbora Mikulášková, Andrea Popelová, Miroslava Blechová, Martin Haluzík, Blanka Železná, Marek Kuzma, Jaroslav Kuneš, Lenka Maletínská
Analogs of anorexigenic neuropeptides, such as prolactin-releasing peptide (PrRP), have a potential as new anti-obesity drugs. In our previous study, palmitic acid attached to the N-terminus of PrRP enabled its central anorexigenic effects after peripheral administration. In this study, two linkers, γ-glutamic acid at Lys11 and a short, modified polyethylene glycol at the N-terminal Ser and/or Lys11, were applied for the palmitoylation of PrRP31 to improve its bioavailability. These analogs had a high affinity and activation ability to the PrRP receptor GPR10 and the neuropeptide FF2 receptor, as well as short-term anorexigenic effect similar to PrRP palmitoylated at the N-terminus...
2017: PloS One
https://www.readbyqxmd.com/read/28820819/response-of-letter-to-the-editor-on-high-resolution-magnetic-resonance-imaging-of-aging-upper-face-fat-compartments
#13
Rémi Foissac, Marc Julien Benatar
No abstract text is available yet for this article.
August 9, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28820812/high-resolution-magnetic-resonance-imaging-of-aging-upper-face-fat-compartments
#14
Sebastian Cotofana, Robert H Gotkin
No abstract text is available yet for this article.
August 9, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28820499/choline-supplementation-normalizes-fetal-adiposity-and-reduces-lipogenic-gene-expression-in-a-mouse-model-of-maternal-obesity
#15
Chauntelle Jack-Roberts, Yaelle Joselit, Khatia Nanobashvili, Rachel Bretter, Olga V Malysheva, Marie A Caudill, Anjana Saxena, Kathleen Axen, Ahmed Gomaa, Xinyin Jiang
Maternal obesity increases fetal adiposity which may adversely affect metabolic health of the offspring. Choline regulates lipid metabolism and thus may influence adiposity. This study investigates the effect of maternal choline supplementation on fetal adiposity in a mouse model of maternal obesity. C57BL/6J mice were fed either a high-fat (HF) diet or a control (NF) diet and received either 25 mM choline supplemented (CS) or control untreated (CO) drinking water for 6 weeks before timed-mating and throughout gestation...
August 18, 2017: Nutrients
https://www.readbyqxmd.com/read/28820447/comprehensive-study-of-multiple-stages-progressing-to-nonalcoholic-steatohepatitis-with-subsequent-fibrosis-in-sd-rats
#16
Lulu Wang, Susu Wu, Minxuan Cai, Ji Ma, Shengcun Li, Maoru Li, Yan Xu, Lixin Wei, Jing Shang
Because of the absence of the time course of histological nonalcoholic fatty hepatitis with subsequent fibrotic progression, the effective approaches available for controlling the onset and progression of non-alcoholic steatohepatitis (NASH) remain limited. Therefore, we detected the serum and liver tissue related lipid metabolism disorder, liver pathology and relative molecular makers alteration dynamically in a high fat-sucrose diet during different time points. High fat-sucrose diet significantly increased the serum lipid level on day 10...
August 18, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28820080/diet-quality-and-its-implications-on-the-cardio-metabolic-physical-and-general-health-of-older-men-the-concord-health-and-ageing-in-men-project-champ
#17
Rosilene V Ribeiro, Vasant Hirani, Alistair M Senior, Alison K Gosby, Robert G Cumming, Fiona M Blyth, Vasi Naganathan, Louise M Waite, David J Handelsman, Hal Kendig, Markus J Seibel, Stephen J Simpson, Fiona Stanaway, Margaret Allman-Farinelli, David G Le Couteur
The revised Dietary Guideline Index (DGI-2013) scores individuals' diets according to their compliance with the Australian Dietary Guideline (ADG). This cross-sectional study assesses the diet quality of 794 community-dwelling men aged 74 years and older, living in Sydney, Australia participating in the Concord Health and Ageing in Men Project; it also examines sociodemographic and lifestyle factors associated with DGI-2013 scores; it studies associations between DGI-2103 scores and the following measures: homoeostasis model assessment - insulin resistance, LDL-cholesterol, HDL-cholesterol, TAG, blood pressure, waist:hip ratio, BMI, number of co-morbidities and medications and frailty status while also accounting for the effect of ethnicity in these relationships...
July 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28819990/effects-of-maternal-high-fat-diet-and-sedentary-lifestyle-on-susceptibility-of-adult-offspring-to-ozone-exposure-in-rats
#18
C J Gordon, P M Phillips, A F M Johnstone, J Schmid, M C Schladweiler, A Ledbetter, S J Snow, U P Kodavanti
Epidemiological and experimental data suggest that obesity exacerbates the health effects of air pollutants such as ozone (O3). Maternal inactivity and calorically rich diets lead to offspring that show signs of obesity. Exacerbated O3 susceptibility of offspring could thus be manifested by maternal obesity. Thirty-day-old female Long-Evans rats were fed a control (CD) or high-fat (HF) (60% calories) diet for 6 wks and then bred. GD1 rats were then housed with a running wheel (RW) or without a wheel (SED) until parturition, creating four groups of offspring: CD-SED, CD-RW, HF-SED and HF-RW...
August 18, 2017: Inhalation Toxicology
https://www.readbyqxmd.com/read/28819898/regulation-of-hepatic-na-k-atpase-in-obese-female-and-male-rats-involvement-of-erk1-2-ampk-and-rho-rock
#19
Julijana Stanimirovic, Milan Obradovic, Anastasija Panic, Voin Petrovic, Dragan Alavantic, Irena Melih, Esma R Isenovic
In this study, we assessed whether the disturbed regulation of sodium/potassium-adenosine-triphosphatase (Na(+)/K(+)-ATPase) occurs as a consequence of obesity-induced IR in sex-specific manner. We also assessed whether alterations of IRS/PI3K/Akt, ERK1/2, AMPKα, and RhoA/ROCK signaling cascades have an important role in this pathology. Female and male Wistar rats (150-200 g, 8 weeks old) were fed a standard laboratory diet or a high-fat (HF) diet (42% fat) for 10 weeks. The activity of hepatic Na(+)/K(+)-ATPase and Rho, and the association of IRS-1/p85 were assessed in liver...
August 17, 2017: Molecular and Cellular Biochemistry
https://www.readbyqxmd.com/read/28819323/excessive-body-fat-linked-to-blunted-somatosensory-cortex-response-to-general-reward-in-adolescents
#20
J F Navas, A Barros-Loscertales, V Costumero-Ramos, J Verdejo-Román, R Vilar-López, A Verdejo-García
BACKGROUND AND AIMS: The brain reward system is key to understanding adolescent obesity in the current obesogenic environment, rich in highly appetising stimuli, to which adolescents are particularly sensitive. We aimed to examine the association between body fat levels and brain reward system responsivity to general (monetary) rewards in male and female adolescents. METHOD: Sixty-eight adolescents (34 females; mean age [standard deviation]=16.56 [1.35]) were measured for body fat levels with bioelectric impedance, and underwent a functional magnetic resonance imaging (fMRI) scan during the Monetary Incentive Delay (MID) task...
August 18, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
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