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Cardiac output; hemodynamics

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https://www.readbyqxmd.com/read/29334615/hemodynamic-and-metabolic-responses-to-self-paced-and-ramp-graded-exercise-testing-protocols
#1
Nicholas M Beltz, Fabiano Amorim, Ann L Gibson, Jeffrey M Janot, Len Kravitz, Christine M Mermier, Nathan Cole, Terence A Moriarty, Tony P Nunez, Sam Trigg, Lance Dalleck
PURPOSE: Recent examinations have shown lower maximal oxygen uptake (VO2max) during traditional ramp (RAMP) compared to self-paced (SPV) graded exercise testing (GXT) attributed to differences in cardiac ouput. The current study examined the differences in hemodyamic and metabolic responses between RAMP and SPV during treadmill exercise. METHODS: Sixteen recreationally trained men (23.7±3.0 yrs) completed two separate treadmill GXT protocols. SPV consisted of five 2-min stages (10 min total) of increasing speed clamped by the Borg RPE6-20 scale...
January 15, 2018: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29327562/development-of-a-porcine-beating-heart-model-of-self-myocardial-retroperfusion-evaluation-of-hemodynamic-and-cardiac-responses-to-ischemia-and-clinical-applications
#2
Daniel Grandmougin, Jean-Mathieu Casse, Antoine Chalon, Yun Luo, Aude Falanga, Vanessa Marie, Fréderique Groubatch-Joineau, Brice Mourer, Marie Grandmougin, David Grandmougin, Guillaume Gauchotte, Juan-Pablo Maureira, Nguyen Tran
BACKGROUND: Retrograde perfusion into the coronary sinus is used to deliver cardioplegia. We developed an in-vivo porcine beating-heart model of self-myocardial retroperfusion (SMR) using the venous route to supply myocardial oxygenation and sought to assess hemodynamic and cardiac responses triggered by SMR before and after a prolonged occlusion of the LAD. METHODS: A bypass-line between the ascending aorta and the coronary sinus was made to perform a selective retrograde perfusion of the great cardiac vein with oxygenated blood (SMR)...
January 9, 2018: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29324512/exercise-capacity-in-patients-with-the-total-artificial-heart
#3
Justin M Canada, Ronald K Evans, Antonio Abbate, Ross Arena, Daniel G Tang, Vigneshwar Kasirajan, Keyur B Shah
There is a dearth of information regarding the functional abilities of patients with the total artificial heart (TAH). Increased utilization of the TAH and patient discharge to home with the portable unit necessitates a shift in focus to quality of life, which includes quantifying and ultimately optimizing functional capacity. To date, only single-patient case studies have described the exercise response of the TAH patient. Fourteen patients with the TAH underwent cardiopulmonary exercise testing with concurrent analysis of TAH device function...
January 10, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/29318729/validation-of-modelflow-estimates-of-cardiac-output-in-hemodialysis-patients
#4
Clare MacEwen, Sheera Sutherland, Jonathan Daly, Christopher Pugh, Lionel Tarassenko
Volume-clamp technology (e.g. Finometer) has become a popular method of collecting continuous, non-invasive, hemodynamic information during hemodialysis. There is minimal data validating the technique in this patient group. A gold standard cardiac output measurement can be obtained using ultrasound dilution in patients with arterio-venous fistulae. Continuous cardiac output was measured in 124 hemodialysis sessions in 27 patients using a volume-clamp device (Finometer PRO). Ultrasound dilution measurement was first taken at baseline (Transonic HD03), then used to calibrate the Finometer...
January 10, 2018: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/29308752/-systemic-pathologic-physiology-parameters-changes-in-sheep-drowning-a-control-study-in-freshwater-and-seawater
#5
Wanjie Yang, Qingguo Feng, Xiaozhi Liu, Qing Wang, Xuefeng Zhao, Rumei Zhang, Kai Wei, Hongyun Teng, Yumei Wang
OBJECTIVE: To compare the systemic pathologic physiology parameter changes in sheep drowning in freshwater and seawater. METHODS: The experimental animals were healthy crossbred sheep. According to the envelope method, 24 sheep were randomly divided into two groups, with 12 animals in each group. The animals in both groups were subjected to mechanical ventilation and analgesia and sedation, the drowning models were reproduced by injecting 10-25 mL/kg of seawater or freshwater into the endotracheal tube of animals...
January 2018: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/29287808/clinical-implications-of-hemodynamic-assessment-during-left-ventricular-assist-device-therapy
#6
REVIEW
Teruhiko Imamura, Ben Chung, Ann Nguyen, Gabriel Sayer, Nir Uriel
Left ventricular assist devices (LVADs) significantly improve outcomes of advanced heart failure patients. However, patients continue to have high readmission rates due to complications ranging from bleeding, thrombosis, heart failure, and infection. Considering that the hallmark benefit of LVAD therapy is improvement in hemodynamics (cardiac unloading and increased cardiac output), hemodynamic assessment on LVAD support is key to better understand these difficult complications and may serve as a tool to resolving them...
December 26, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/29287136/cerebrovascular-hemodynamics-in-fetuses-with-congenital-heart-disease
#7
Tingting Man, Yihua He, Ying Zhao, Lin Sun, Xiaowei Liu, Shuping Ge
BACKGROUND AND OBJECTIVE: It is hypothesized that diminished cerebral vascular resistance or the "brain sparing effect" is associated with fetuses with complex congenital heart defects (CHD) and may affect their neurodevelopmental outcome. An alternative explanation is that it is related to the location, cardiac output, pressure, and resistance in left heart obstructive CHDs. We sought to determine the effects of various left and right heart obstructive defects on the cerebral and placental hemodynamics and to evaluate the utility of these variables for the assessment and prognosis of CHDs...
December 2017: Echocardiography
https://www.readbyqxmd.com/read/29286554/effect-of-intravenous-administration-of-cobalt-chloride-to-horses-on-clinical-and-hemodynamic-variables
#8
T A Burns, K A Dembek, A Kamr, S B Dooley, L K Dunbar, T K Aarnes, L S Bednarski, C O'Brien, J Lakritz, B Byrum, A Wade, R Farmer, S Tan, R E Toribio
BACKGROUND: Cobalt chloride (CoCl2 ) is administered to racehorses to enhance performance. The purpose of this study was to evaluate the clinical, cardiovascular, and endocrine effects of parenterally administered CoCl2 . OBJECTIVES: To describe the effects of weekly intravenous doses of CoCl2 on Standardbred horses. ANIMALS: Five, healthy Standardbred mares. METHODS: Prospective, randomized, experimental dose-escalation pilot...
December 29, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/29283315/comparison-of-central-hemodynamic-parameters-for-young-basketball-athletes-and-control-group
#9
Yahui Zhang, Xiaobing Fan, Lin Qi, Lisheng Xu, Chenglin Du
BACKGROUND: Long-term exercise training may have negative effects on cardiovascular functions. Measurement and calculation of central hemodynamic parameters can comprehensively evaluate the cardiovascular functions. This study aims to compare the central hemodynamics between young basketball athletes and matched controls. METHODS: Total 19 young long-term trained male basketball athletes and 17 matched male recreationally active controls participated. The central hemodynamic parameters such as central blood pressure, pulse pressure, heart rate (HR), augmentation index normalised to 75 bpm (AIx@HR75), augmentation index (AIx), ejection duration (ED), sub-endocardial viability ratio (SEVR) were measured, and total peripheral resistance (TPR), stroke volume (SV) and cardiac output (CO) were calculated...
December 28, 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/29278864/stroke-volume-recruitability-during-the-third-trimester-of-pregnancy
#10
Sandra Herrera, Maggie J Kuhlmann-Capek, Sarah C Rogan, Antonio F Saad, George R Saade, Gary D V Hankins, Luis D Pacheco
OBJECTIVE:  It is unknown whether the heart operates in the ascending or flat portion of the Starling curve during normal pregnancy. Pregnant women do not respond to the passive leg-raising maneuver secondary to mechanical obstruction of the inferior vena cava by the gravid uterus. Our objective was to evaluate if administration of a fluid bolus increases baseline stroke volume (SV) among healthy pregnant patients during the third trimester. STUDY DESIGN:  Healthy pregnant women who underwent elective term cesarean sections were included...
December 26, 2017: American Journal of Perinatology
https://www.readbyqxmd.com/read/29277506/high-output-cardiac-failure-and-coronary-steal-with-an-arteriovenous-fistula
#11
Amtul Aala, Sairah Sharif, Leslie Parikh, Paul C Gordon, Susie L Hu
Creation of an arteriovenous access for hemodialysis can provoke a sequence of events that significantly affects cardiovascular hemodynamics. We present a 78-year-old man with end-stage renal disease and concomitant coronary artery disease previously requiring coronary artery bypass grafting including a left internal mammary graft to the left anterior descending artery, ischemic cardiomyopathy with left ventricular systolic dysfunction, and severe aortic stenosis who developed hypotension unresponsive to medical therapy after recent angioplasty of his ipsilateral arteriovenous fistula for high-grade outflow stenosis...
December 22, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29275921/patients-with-hypertensive-responses-to-exercise-or-dobutamine-stress-testing-differ-in-resting-hypertensive-phenotype
#12
Andrew Kieu, Armaan Shaikh, Mark Kaeppler, Robert J Miles, Michael E Widlansky
Little is known of the importance of echocardiographic measures of resting systemic vascular resistance (SVR), cardiac output, and diastolic function in the development of a hypertensive response during dobutamine stress echocardiography. We performed a retrospective review of 325 subjects who underwent stress echocardiography and a resting echocardiogram on the same day. Logistical regressions were performed to determine associations between hypertensive response to each type of stress test and clinical and hemodynamic measurements obtained by transthoracic echocardiography...
December 14, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/29250516/use-of-therapeutic-plasma-exchange-during-extracorporeal-life-support-in-critically-ill-cardiac-children-with-thrombocytopenia-associated-multi-organ-failure
#13
Mei Chong, Alejandro J Lopez-Magallon, Lucas Saenz, Mahesh S Sharma, Andrew D Althouse, Victor O Morell, Ricardo Munoz
Background: Thrombocytopenia-associated multi-organ failure (TAMOF) in children is a well-described factor for increased hospital mortality. Low cardiac output syndrome (LCOS) and the effects of cardiopulmonary bypass may manifest with several adverse physiologic and immunologic effects, with varying degrees of thrombocytopenia and multi-organ dysfunction, sometimes very similar to TAMOF. LCOS is a common occurrence in children with critical heart disease, presenting in as much as 23...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29247499/cardiac-output-changes-after-osmotic-therapy-in-neurosurgical-and-neurocritical-care-patients-a-systematic-review-of-the-clinical-literature
#14
Georgia Tsaousi, Elisabetta Stazi, Marco Cinicola, Federico Bilotta
AIM: Osmotherapy constitutes a first-line intervention for intracranial hypertension management. However, hyperosmolar solutes exert various systematic effects, among which their impact on systemic hemodynamics is poorly clarified. This review aims to appraise the clinical evidence of the effect of mannitol and hypertonic saline (HTS) on cardiac performance in neurosurgical and neurocritical care patients. METHOD: A database search was conducted to identify randomized clinical trials and observational studies reporting HTS or mannitol use in acute brain injury setting...
December 16, 2017: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29246828/the-pathophysiology-of-the-vasovagal-response
#15
David L Jardine, Wouter Wieling, Michele Brignole, Jacques W M Lenders, Richard Sutton, Julian Stewart
In Part I we found that the classic studies of vasovagal syncope, done on fit young subjects, over stated vasodilatation as the dominant hypotensive mechanism. Since 1980, blood pressure and cardiac output have been measured continuously using non-invasive methods during tilt, mainly in patients with recurrent syncope, including women and the elderly. This has allowed us to analyse in more detail the complex sequence of hemodynamic changes leading up to syncope in the laboratory. All tilt-sensitive patients appear to progress through 4 phases: 1 early stabilisation, 2 circulatory instability, 3 terminal hypotension and 4 recovery...
December 12, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29244793/effects-of-epinephrine-on-hemodynamic-changes-during-cardiopulmonary-resuscitation-in-a-neonatal-piglet-model
#16
Michael Wagner, Po-Yin Cheung, Elliott S Li, Tze-Fun Lee, Min Lu, Megan O'Reilly, Monika Olischar, Georg M Schmölzer
BACKGROUND: Asphyxia is the most common reason for newborns to fail to make a successful fetal to neonatal transition. There is currently a lack of data evaluating hemodynamic effects of epinephrine during neonatal cardiopulmonary resuscitation. METHODS: Twenty-four newborn piglets were exposed to asphyxia. Thereafter, positive pressure ventilation was commenced for 30 s, followed by chest compressions (CC). Piglets were randomized into three experimental groups: 3:1 compression:ventilation ratio; CC during sustained inflation (SI) at a rate of 90 CC per minute, or CC during SI at a rate of 120 CC per minute...
December 15, 2017: Pediatric Research
https://www.readbyqxmd.com/read/29230392/non-invasive-monitoring-of-cardiac-output-in-critical-care-medicine
#17
REVIEW
Lee S Nguyen, Pierre Squara
Critically ill patients require close hemodynamic monitoring to titrate treatment on a regular basis. It allows administering fluid with parsimony and adjusting inotropes and vasoactive drugs when necessary. Although invasive monitoring is considered as the reference method, non-invasive monitoring presents the obvious advantage of being associated with fewer complications, at the expanse of accuracy, precision, and step-response change. A great many methods and devices are now used over the world, and this article focuses on several of them, providing with a brief review of related underlying physical principles and validation articles analysis...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/29230366/comparison-between-radial-artery-tonometry-pulse-analyzer-and-pulsed-doppler-echocardiography-derived-hemodynamic-parameters-in-cardiac-surgery-patients-a-pilot-study
#18
Rashad Zayat, Andreas Goetzenich, Ju-Yeon Lee, HeeJung Kang, So-Hyun Jansen-Park, Thomas Schmitz-Rode, Giulia Musetti, Heike Schnoering, Rüdiger Autschbach, Nima Hatam, Ali Aljalloud
Background: Bedside non-invasive techniques, such as radial artery tonometry, to estimate hemodynamic parameters have gained increased relevance as an attractive alternative and efficient method to measure hemodynamics in outpatient departments. For our pilot study, we sought to compare cardiac output (CO), and stroke volume (SV) estimated from a radial artery tonometry blood pressure pulse analyzer (BPPA) (DMP-Life, DAEYOMEDI Co., Gyeonggi-do, South Korea) to pulsed-wave Doppler (PWD) echocardiography derived parameters...
2017: PeerJ
https://www.readbyqxmd.com/read/29227330/total-bile-acid-levels-are-associated-with-left-atrial-volume-and-cardiac-output-in-patients-with-cirrhosis
#19
Andrei M Voiosu, Signe Wiese, Theodor A Voiosu, Jens Hove, Flemming Bendtsen, Søren Møller
BACKGROUND AND AIMS: Bile acids (BAs) are potent signaling molecules involved in the regulation of several metabolic and functional aspects of cardiovascular homeostasis. BA pool alteration in cirrhosis may contribute toward the development of hemodynamic and cardiac disturbances. We aimed to investigate the association between total BA levels and echocardiographic and biochemical markers of cardiac dysfunction in cirrhotic patients. METHODS: Cirrhotic patients were enrolled prospectively in this hypothesis-generating study and evaluated for cardiac and hemodynamic dysfunction through clinical, echocardiographic, and biochemical means...
December 8, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29222766/electrical-velocimetry-for-non-invasive-monitoring-of-the-closure-of-the-ductus-arteriosus-in-preterm-infants
#20
Ana Rodríguez Sánchez de la Blanca, M Sánchez Luna, N González Pacheco, M Arriaga Redondo, N Navarro Patiño
Closure of a patent ductus arteriosus (PDA) in preterm infants modifies cardiac output and induces adaptive changes in the hemodynamic situation. The present study aims to analyze those changes, through a non-invasive cardiac output monitor based on blood electrical velocimetry, in preterm babies. A prospective observational study of preterm infants with a gestational age of less than 28 weeks, and a hemodynamic significant PDA, requires intravenous ibuprofen or surgical closure. All patients were monitored with electrical velocimetry before treatment and through the following 72 h...
February 2018: European Journal of Pediatrics
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