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https://www.readbyqxmd.com/read/28726045/the-use-of-psychological-supportive-care-services-and-psychotropic-drugs-in-patients-with-early-stage-breast-cancer-a-comparison-between-two-institutions-on-two-continents
#1
Orit Kaidar-Person, Icro Meattini, Allison M Deal, Giulio Francolini, Giulio Carta, Lauren Terzo, Jayne Camporeale, Hyman Muss, Lawrence B Marks, Lorenzo Livi, Deborah K Mayer, Timothy M Zagar
The aim of this study was to evaluate the mental health consumption among patients with early-stage breast cancer in two radiation oncology departments in two countries (USA and Italy). Data were extracted from the medical records of consecutive patients treated between 2014 and 2015 in two centers. Extracted data included patient's demographics, treatment, referral to psychological supportive care programs, and prescribed psychotropic drugs. Data from the two centers were compared using Student's t, Wilcoxon, Fisher's exact, and Jonckheere-Terpstra tests...
August 2017: Medical Oncology
https://www.readbyqxmd.com/read/28722774/-promoting-continuity-of-care-specialist-nurses-role-experiences-in-gynaecological-oncology-a-qualitative-study
#2
Andrea Kobleder, Hanna Mayer, Larissa Gehrig, Beate Senn
AIMS AND OBJECTIVES: To investigate the experiences of specialist nurses in Switzerland concerning their role of caring for women with gynaecological cancer. BACKGROUND: Women with gynaecological cancer often face complex situations, which require an integrative and quality-assured approach by the healthcare system. Specialist nurses can play an important role in supporting these patients. However, in countries where the role of specialist nurses is at a developmental stage, their role lacks clarity...
July 19, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28722668/coupling-to-a-cancer-selective-heparan-sulfate-targeted-branched-peptide-can-by-pass-breast-cancer-cell-resistance-to-methotrexate
#3
Lorenzo Depau, Jlenia Brunetti, Chiara Falciani, Silvia Scali, Giulia Riolo, Elisabetta Mandarini, Alessandro Pini, Luisa Bracci
Cancer-selective tetra-branched peptides, named NT4, can be coupled to different functional units for cancer cell imaging or therapy. NT4 peptides specifically bind to lipoprotein receptor-related proteins (LRP) receptors and to heparan sulfate chains on membrane proteoglycans and can be efficiently internalized by cancer cells expressing these membrane targets. Since binding and internalization of NT4 peptides is mediated by specific NT4 receptors on cancer cell membranes and this may allow drug resistance produced by drug membrane transporters to be by-passed, we tested the ability of drug-armed NT4 to by-pass drug resistance in cancer cell lines...
July 6, 2017: Oncotarget
https://www.readbyqxmd.com/read/28721645/is-cancer-information-exchanged-on-social-media-scientifically-accurate
#4
Elizabeth A Gage-Bouchard, Susan LaValley, Molli Warunek, Lynda Kwon Beaupin, Michelle Mollica
Cancer patients and their caregivers are increasingly using social media as a platform to share cancer experiences, connect with support, and exchange cancer-related information. Yet, little is known about the nature and scientific accuracy of cancer-related information exchanged on social media. We conducted a content analysis of 12 months of data from 18 publically available Facebook Pages hosted by parents of children with acute lymphoblastic leukemia (N = 15,852 posts) and extracted all exchanges of medically-oriented cancer information...
July 19, 2017: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/28720266/strengths-and-resources-used-by-australian-and-danish-adult-patients-and-their-family-caregivers-during-treatment-for-cancer
#5
E Coyne, K B Dieperink, B Østergaard, D K Creedy
PURPOSE: Family plays an essential role in supporting the patient with cancer, however, relatively little attention has been given to understanding the strengths and resources of the family unit across different settings and countries. This study aims to investigate the strengths and resources of patients and family members in Australia and Denmark. METHODS: Using a descriptive, cross-sectional design, 232 patient and family participants from inpatient and outpatient oncology services in Australia and Denmark completed paper based surveys that included the Family Hardiness Index (FHI) and Family Crisis Orientated Personal Evaluation Scales (F-COPES), together with demographic and health information...
August 2017: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
https://www.readbyqxmd.com/read/28719921/-patient-s-autonomy-and-information-in-psycho-oncology-computer-based-distress-screening-for-an-interactive-treatment-planning-epos-react
#6
Norbert Schäffeler, Jana Sedelmaier, Hannah Möhrer, Katrin Ziser, Johanna Ringwald, Martin Wickert, Sara Brucker, Florian Junne, Stephan Zipfel, Martin Teufel
To identify distressed patients in oncology using screening questionnaires is quite challenging in clinical routine. Up to now there is no evidence based recommendation which instrument is most suitable and how to put a screening to practice. Using computer based screening tools offers the possibility to automatically analyse patient's data, inform psycho-oncological and medical staff about the results, and use reactive questionnaires. Studies on how to empower patients in decision making in psycho-oncology are rare...
July 2017: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/28717412/diffusion-magnetic-resonance-imaging-a-molecular-imaging-tool-caught-between-hope-hype-and-the-real-world-of-personalized-oncology
#7
REVIEW
Abhishek Mahajan, Sneha S Deshpande, Meenakshi H Thakur
"Personalized oncology" is a multi-disciplinary science, which requires inputs from various streams for optimal patient management. Humongous progress in the treatment modalities available and the increasing need to provide functional information in addition to the morphological data; has led to leaping progress in the field of imaging. Magnetic resonance imaging has undergone tremendous progress with various newer MR techniques providing vital functional information and is becoming the cornerstone of "radiomics/radiogenomics"...
June 28, 2017: World Journal of Radiology
https://www.readbyqxmd.com/read/28713868/21st-century-cardio-oncology-identifying-cardiac-safety-signals-in-the-era-of-personalized-medicine
#8
Calvin Chen Sheng, Laleh Amiri-Kordestani, Todd Palmby, Thomas Force, Charles C Hong, Joseph C Wu, Kevin Croce, Geoffrey Kim, Javid Moslehi
Cardiotoxicity is a well-established complication of oncology therapies. Cardiomyopathy resulting from anthracyclines is a classic example. In the past decade, an explosion of novel cancer therapies, often targeted and more specific than traditional therapies, has revolutionized oncology therapy and dramatically changed cancer prognosis. However, some of these therapies have introduced an assortment of cardiovascular (CV) complications. At times, these devastating outcomes have only become apparent after drug approval and have limited the use of potent therapies...
August 2016: JACC. Basic to Translational Science
https://www.readbyqxmd.com/read/28712100/the-role-of-genomic-techniques-in-predicting-response-to-radiation-therapy
#9
REVIEW
Noelle L Williams, Tu Dan, Nicholas G Zaorsky, Shivank Garg, Robert B Den
The understanding of the relationship between genetic variation and an individual patient's response to radiation therapy (RT) has gained significant ground over the past several years. Genetic markers have been identified that could ultimately serve as the foundation for predictive models in clinical practice, and that hold the potential to revolutionize the delivery of precision medicine in oncology. Single nucleotide polymorphisms, single genes, and/or gene signatures could ultimately serve as the basis for patient stratification in prospective clinical trials...
July 15, 2017: Oncology (Williston Park, NY)
https://www.readbyqxmd.com/read/28712058/reliance-on-medicinal-plant-therapy-among-cancer-patients-in-jamaica
#10
Kimberley Foster, Novie Younger, William Aiken, Doreen Brady-West, Rupika Delgoda
PURPOSE: Patients' perspective of their treatment regime plays a vital role in its success. Recognizing the high prevalence of medicinal plant usage among Jamaicans at large, we investigated the engagement of such remedies by cancer patients, with the aim of uncovering self-medicating habits, perceptions and details of utilized plants. METHODS: A structured, interviewer-based questionnaire was administered to 100 patients attending the oncology and urology clinics at the University Hospital of the West Indies in Kingston, Jamaica...
July 15, 2017: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/28708234/physicists-views-on-hadrontherapy-a-survey-of-members-of-the-italian-association-of-medical-physics-aifm
#11
Tommaso Giandini, Chiara Tenconi, Mauro Carrara, Mario Ciocca, Stefania Russo, Costanza M V Panaino, Federica Cattani, Delia Ciardo, Sara Morlino, Barbara Avuzzi, Nice Bedini, Sergio Villa, Giulia Marvaso, Paola Romanelli, Azusa Hasegawa, Barbara Vischioni, Francesca Valvo, Barbara A Jereczek-Fossa, Roberto Orecchia, Riccardo Valdagni, Emanuele Pignoli
BACKGROUND: This study was based on a survey to investigate perceptions of hadrontherapy of the members of the Italian Association of Medical Physics (AIFM). The survey was digitally submitted to the 991 members between the end of January and the beginning of April 2016. METHODS: A 19-item questionnaire was designed focusing on advantages and disadvantages of hadrontherapy, current status and possible future improvements, and need and opportunities for future investments in Italy and abroad...
July 8, 2017: Tumori
https://www.readbyqxmd.com/read/28702411/diffuse-large-b-cell-lymphoma-in-elderly-experience-from-a-tertiary-care-oncology-center-in-south-india
#12
K N Lokesh, M C Suresh Babu, K C Lakshmaiah, K Govind Babu, Smitha C Saldanha, D Loknatha, Linu Abraham Jacob, S Vishwanath, C S Premalatha, P R Kiran
INTRODUCTION: Diffuse large B-cell lymphoma (DLBCL) is the most frequent non-Hodgkins lymphoma in the elderly. With the rising proportion of older persons in India, it is important to study current patterns and management of this disease, given that data in this regard are scarce in Indian settings. The aim of this study was to document the clinical features of DLBCL among elderly patients and their outcome over 7 years at a tertiary care oncology center. MATERIALS AND METHODS: This was a retrospective records review of 119 DLBCL cases between January 2007 and January 2015 aged 60 years and above done at Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka, India...
April 2017: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/28698010/compliance-with-research-standards-within-gynecologic-oncology-fellowship-a-gynecologic-oncology-fellowship-research-network-gofrn-study
#13
Laura J Moulton, Chad M Michener, Kimberly Levinson, Lauren Cobb, Jill Tseng, Amelia Jernigan
OBJECTIVES: Participation in clinical and basic science research is emphasized in gynecologic oncology training. We sought to identify trends in adherence to expected research practices and reasons for non-adherence among gynecologic oncology fellows. METHODS: An anonymous 31-question online survey assessing academic behaviors, including IRB compliance, authorship assignment, data sharing, and potential barriers to non-adherence was distributed to all SGO gynecologic oncology fellow members in July 2016...
July 8, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28692231/-the-menopausal-hormone-therapy-in-2016
#14
Evangelia Pavlidou, Paul Pirtea, Isabelle Streuli
The menopausal hormone therapy (MHT) is the first line treatment for climacteric symptoms related to estrogen deficiency. A personalized evaluation of the benefit-risk ratio should precede a MHT prescription, and take into consideration cardiovascular, thromboembolic, oncological and osteoporosis risks. MHT should be prescribed at the lowest effective dose and for the shortest duration, respecting the window of opportunity in the 10 years following menopause or before the age of 60 years. The choice of the MHT type depends on the patient's profile, her medical history and personal preferences, with the aim of improving quality of life from a physical, psychological and sexual point of view...
October 26, 2016: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28686055/a-stakeholder-informed-randomized-controlled-comparative-effectiveness-study-of-an-order-prescribing-intervention-to-improve-colony-stimulating-factor-use-for-cancer-patients-receiving-myelosuppressive-chemotherapy-the-tracer-study
#15
Aasthaa Bansal, Sean D Sullivan, Dawn L Hershman, Gary H Lyman, William E Barlow, Jeannine S McCune, Scott D Ramsey
Colony stimulating factors (CSF) are widely prescribed to avoid febrile neutropenia (FN) among cancer patients receiving chemotherapy, but studies show their use is often not consistent with practice guidelines. In addition, there is limited high quality evidence assessing benefits and harms of primary prophylactic-CSF (PP-CSF) in the setting of chemotherapy that poses an intermediate risk of FN. To address these issues, with funding from the Patient Centered Outcomes Research Institute (PCORI) and the National Cancer Institute's Community Oncology Research Program, SWOG is sponsoring a prospective, cluster randomized controlled pragmatic trial of an automated order entry protocol for PP-CSF among patients with breast, lung and colorectal cancer receiving myelosuppressive chemotherapy, with a nested randomized controlled trial of PP-CSF for patients receiving intermediate risk chemotherapy...
July 7, 2017: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/28681208/surgical-considerations-in-the-optimal-management-of-patients-with-malignant-brain-tumors
#16
REVIEW
Jaclyn J Renfrow, Roy E Strowd, Adrian W Laxton, Stephen B Tatter, Carol P Geer, Glenn J Lesser
Advances in technology are revolutionizing medicine and the limits of what we can offer to our patients. In neurosurgery, technology continues to reduce morbidity, increase surgical accuracy, facilitate tissue acquisition, and promote novel techniques for prolonging survival in patients with neuro-oncologic disease. Surgery has been the backbone of glioma diagnosis and treatment by providing adequate, high quality material for precise histologic diagnosis, and genomic characterization in the setting of significant intratumoral heterogeneity, thus allowing personalized treatment selection in the clinic...
August 2017: Current Treatment Options in Oncology
https://www.readbyqxmd.com/read/28681207/optimal-therapy-of-advanced-stage-mesothelioma
#17
REVIEW
Maria M J Disselhorst, Sjaak J A Burgers, Paul Baas
The optimal treatment of patients with advanced malignant pleural mesothelioma (MPM) has not yet been discovered. With the aid of an increased insight in the molecular pathways and the development of combinations of Immuno-Oncology (IO), drugs new therapies are available. The personalization of treatment by cell cultures and pathway analysis attracts more attention nowadays. It is conceivable that in the near future the treatment of patients with MPM will consist of a combination of IO drugs or specific pathway inhibitors...
August 2017: Current Treatment Options in Oncology
https://www.readbyqxmd.com/read/28680276/resource-utilization-and-costs-of-managing-patients-with-advanced-melanoma-a-canadian-population-based-study
#18
F Gwadry-Sridhar, S Nikan, A Hamou, S J Seung, T Petrella, A M Joshua, S Ernst, N Mittmann
BACKGROUND: The use and detailed costs of services provided for people with advanced melanoma (amel) are not well known. We conducted an analysis to determine the use of health care services and the associated costs delineated by relevant attributable costs, which we defined for subjects in the province of Ontario. METHODS: Through the Ontario Cancer Data Linkage Project, a cohort of amel patients with diagnoses between 31 August 2005 and 2012 (follow-up to 2013) and with valid International Classification of Diseases (9th revision, Clinical Modification) 172 codes and histology codes was identified...
June 2017: Current Oncology
https://www.readbyqxmd.com/read/28679288/chemotherapy-induced-cardiotoxicity-in-children
#19
Neha Bansal, Shahnawaz Amdani, Emma R Lipshultz, Steven E Lipshultz
With advances in clinical oncology, the burden of morbidity and mortality for cancer survivors due to the cardiac side effects of the chemotherapy is steadily increasing. Treatment-related cardiac damage is progressive and often irreversible. Primary prevention of cardiotoxicity during treatment is possible with strategies like limiting the cumulative anthracycline dose, the use of anthracycline structural analogs, and especially cardioprotective agents. Areas covered: This review covers the various cardiotoxic chemotherapeutic agents, the pathophysiology of cardiotoxicity due to anthracyclines, and the clinical and subclinical presentations and progression of childhood anthracycline cardiotoxicity...
July 13, 2017: Expert Opinion on Drug Metabolism & Toxicology
https://www.readbyqxmd.com/read/28669013/narrative-medicine-perspectives-on-patient-identity-and-integrative-care-in-neuro-oncology
#20
Robert B Slocum, Tracy A Howard, John L Villano
Narrative Medicine sessions can encourage patients to rediscover personal identity and meaning by telling or writing their stories. We explored this process to improve care and quality of life for brain cancer patients in an academic neuro-oncology program. Brain cancer and its treatments may threaten a patient's quality of life and sense of self in many ways, including impaired cognitive skills, loss of memory, reduced coordination, and limited capacity for self-expression. The impact of symptoms and side effects on quality of life must be evaluated in terms of each patient's identity and may be understood in terms of each patient's story...
July 1, 2017: Journal of Neuro-oncology
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