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25-OH-Vitamin-D

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https://www.readbyqxmd.com/read/28099554/no-correlation-was-observed-between-vitamin-d-levels-and-disability-of-patients-with-multiple-sclerosis-between-latitudes-18%C3%A2-and-30%C3%A2-south
#1
Yara Dadalti Fragoso, Tarso Adoni, Soniza Vieira Alves-Leon, Samira L Apostolos-Pereira, Walter Oleschko Arruda, Joseph B Bidin Brooks, Henrique S Rodrigues Cal, Carlos A Albuquerque Damasceno, Paulo Diniz Gama, Marcus V Magno Goncalves, Carlos A da Silva de Jesus, Suzana C Nunes Machado, Letícia Fezer Mansur, Andre P da Cunha Matta, Maria Fernanda Mendes, Rogerio Rizo Morales, Adaucto Wanderley da Nobrega-Jr, Monica K Fiuza Parolin, Mario Pietro Peres, Marlise de Castro Ribeiro, Heloisa Helena Ruocco, Simone Scherpenhuijzen, Fabio Siquinelli, Patrick N Stoney, Daniel Lima Varela, Audred Cristina Biondo Eboni, Caroline Vieira Spessotto, Elisa Teixeira da Rocha, Pamela Emanuele Lacerda
Objective: Vitamin D has taken center stage in research and treatment of multiple sclerosis (MS). The objective of the present study was to assess the serum vitamin D levels of a large population of patients with MS and controls living in a restricted tropical area. Methods: Data from 535 patients with MS and 350 control subjects were obtained from 14 cities around the Tropic of Capricorn. Results: The mean serum 25-OH vitamin D level was 26...
January 2017: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/28099429/vitamin-d-insufficiency-in-neonatal-hypoxic-ischemic-encephalopathy
#2
Danielle W Lowe, Bruce W Hollis, Carol L Wagner, Thomas Bass, David A Kaufman, Michael J Horgan, Laurence M Givelichian, Koravangatta Sankaran, Jerome Y Yager, Lakshmi D Katikaneni, Don Wiest, Dorothea Jenkins
BACKGROUND: Vitamin D has neuroprotective and immunomodulatory properties, and deficiency is associated with worse stroke outcomes. Little is known about effects of hypoxia-ischemia or hypothermia treatment on vitamin D status in neonates with hypoxic-ischemic encephalopathy (HIE). We hypothesized vitamin D metabolism would be dysregulated in neonatal HIE altering specific cytokines involved in Th17 activation, which might be mitigated by hypothermia. METHODS: We analyzed short term relationships between 25(OH) and 1,25(OH)2 vitamin D, vitamin D binding protein, and cytokines related to Th17 function in serum samples from a multicenter randomized controlled trial of hypothermia 33(0)C for 48h after HIE birth versus normothermia in 50 infants with moderate to severe HIE...
January 18, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28088646/bone-microarchitecture-in-adolescent-boys-with-autism-spectrum-disorder
#3
Ann M Neumeyer, Natalia Cano Sokoloff, Erin McDonnell, Eric A Macklin, Christopher J McDougle, Madhusmita Misra
BACKGROUND: Boys with autism spectrum disorder (ASD) have lower areal bone mineral density (aBMD) than typically developing controls (TDC). Studies of volumetric BMD (vBMD) and bone microarchitecture provide information about fracture risk beyond that provided by aBMD but are currently lacking in ASD. OBJECTIVES: To assess ultradistal radius and distal tibia vBMD, bone microarchitecture and strength estimates in adolescent boys with ASD compared to TDC. DESIGN/METHODS: Cross-sectional study of 34 boys (16 ASD, 18 TDC) that assessed (i) aBMD at the whole body (WB), WB less head (WBLH), hip and spine using dual X-ray absorptiometry (DXA), (ii) vBMD and bone microarchitecture at the ultradistal radius and distal tibia using high-resolution peripheral quantitative CT (HRpQCT), and (iii) bone strength estimates (stiffness and failure load) using micro-finite element analysis (FEA)...
January 11, 2017: Bone
https://www.readbyqxmd.com/read/28078870/assessing-the-association-between-25-oh-vitamin-d-levels-and-roma-score-in-a-population-of-obese-women
#4
E Anastasi, D Capoccia, T Granato, V Viggiani, S Tartaglione, L Manganaro, A Angeloni, F Leonetti
The “Risk of Malignancy Algorithm” (ROMA) combines the diagnostic power of the CA125 and HE4 markers with menopausal status to predict the risk for developing epithelial ovarian cancer (EOC). The aim of this study was to evaluate the association between 25-OH vitamin D levels and ROMA score in obese women. One hundred and eighteen patients with a Body Mass Index (BMI) > 30 kg/m2 (Group 1) and 80 women with a BMI less than 25 kg / m² (Group 2) were studied. The 25-OH vitamin D was quantified with LUMIPULSE® G 1200...
October 2016: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28078791/effects-of-stem-cell-transplantation-on-bone-mineral-density-and-vitamin-d-status-in-children-with-thalassemia-major
#5
Dilek Gürlek Gökçebay, Namik Ozbek, Arzu Yazal Erdem, Vildan Culha, Nese Yarali, Pamir Isik, Zekai Avci, Fatih Azik, Fatma Demirel, Bahattin Tunc
HSCT is a curative treatment in TM, but conditioning and immunosuppressive treatment may affect bone metabolism. In this retrospective study, we aimed to compare BMD, vitamin D status, and growth in children with TM who underwent HSCT to those in children with TD TM. Twenty-three children with TM who underwent HSCT (mean age 7.1 years [1.03-14.7]) and 24 children with TD thalassemia (mean age 9.8 years [1.6-14]) were recruited. Lumbar spine BMD of TD thalassemia patients was higher than those in patients who had HSCT at both baseline and second-year assessments (P=...
January 12, 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/28075425/management-of-fibromyalgia-practical-guides-from-recent-evidence-based-guidelines
#6
Winfried Häuser, Jacob Ablin, Serge Perrot, Mary-Ann Fitzcharles
Fibromyalgia (FM) is a prevalent and costly condition worldwide, affecting approximately 2% of the general population. Recent evidence- and consensus-based guidelines from Canada, Germany, Israel and the European League Against Rheumatism aim to support physicians in achieving a comprehensive diagnostic work-up of patients with chronic widespread pain (CWP) and to assist patients and physicians in shared decision making on treament options. Every patient with CWP requires at the first medical evaluation a complete history, medical examination and some laboratory tests (complete blood count, C-reactive protein, serum calcium, creatine phosphokinase, thyroid stimulating hormone, 25-OH vitamin D) to screen for metabolic or inflammatory causes of CWP...
January 4, 2017: Polskie Archiwum Medycyny Wewnętrznej
https://www.readbyqxmd.com/read/28070764/serum-25-oh-vitamin-d-levels-in-systemic-sclerosis-analysis-of-140-patients-and-review-of-the-literature
#7
Dilia Giuggioli, M Colaci, G Cassone, P Fallahi, F Lumetti, A Spinella, F Campomori, A Manfredi, C U Manzini, A Antonelli, C Ferri
Hypovitaminosis D is increasingly reported in autoimmune diseases. We investigated the 25-OH-vitamin D (25-OH-vitD) levels in systemic sclerosis (SSc) patients, in correlation with disease's features. We measured the 25-OH-vitD serum levels in 140 consecutive patients (F/M 126/15; mean age 61 ± 15.1 years), 91 without (group A) and 49 with (group B) 25-OH-cholecalciferol supplementation. Patients of group A invariably showed low 25-OH-vitD levels (9.8 ± 4.1 ng/ml vs. 26 ± 8.1 ng/ml of group B); in particular, 88/91 (97%) patients showed vitamin D deficiency (<20 ng/ml), with very low vitamin D levels (<10 ng/ml) in 40 (44%) subjects...
January 9, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28068803/annals-express-artifactual-25-oh-vitamin-d-level-in-multiple-myeloma
#8
Michal Wen Sheue Ong, Rashim Salota, Tracy Reeman, Lapsley Marta, Lydia Jones
The most commonly used techniques to measure vitamin D are automated immunoassays which are known to be affected by interferences, especially from immunoglobulins present in the patient's serum. We present a case of a patient with myeloma in whom interference with the vitamin D assay was identified. An eighty-three year old female, known to have IgG myeloma was found to have a high concentration of 25-OH vitamin D on a routine test without any signs of vitamin D toxicity. She was not taking vitamin D supplements or any other multivitamin preparation and had minimal sun exposure...
January 1, 2017: Annals of Clinical Biochemistry
https://www.readbyqxmd.com/read/28063327/serum-levels-of-fibroblast-growth-factor-23-are-elevated-in-patients-with-active-lupus-nephritis
#9
Aline L Resende, Rosilene M Elias, Myles Wolf, Luciene M Dos Reis, Fabiana G Graciolli, Geuza D Santos, Cristiane B Dias, Vanda Jorgetti, Viktoria Woronik, Rosa M A Moysés
BACKGROUND: Fibroblast growth factor 23 (FGF23), a phosphate-regulating hormone is an established cardiovascular risk factor. Recently, FGF23 has been related to inflammation. Lupus is an inflammatory disease, and whether FGF23 is associated with Lupus nephritis (LN) activity is unknown. MATERIALS AND METHODS: We studied 15 pre-menopausal patients with recent LN diagnose (⩽2months) and compared them to 1:1 age-matched healthy control group. We measured serum levels of intact FGF23, interleukin-6 (IL-6), tumor necrosis factor α (TNFα), and urinary levels of monocyte chemotactic protein (MCP1)...
January 4, 2017: Cytokine
https://www.readbyqxmd.com/read/28060972/-vitamin-d-and-parathyroid-hormone-levels-and-bone-mineral-density-in-patients-undergoing-hematopoietic-cell-transplantation
#10
Pablo Florenzano, Daniel Ernst, Nicole Lustig, Patricio Rojas, Pablo Ramírez, Claudia Campusano
BACKGROUND: Patients undergoing hematopoietic cell transplantation (HCT) are at increased risk of developing osteoporosis. AIM: To determine the frequency and severity of Vitamin D deficiency, secondary hyperparathyroidism and low bone mass in patients undergoing HCT. PATIENTS AND METHODS: Analysis of the database of patients undergoing HCT in our institution in the 2010-2015 period. We searched for patients with measurements of 25-OH vitamin D (25OHD), parathyroid hormone (PTH) and bone densitometry by double beam X ray absorptiometry (DXA) prior and up to one year after HCT...
September 2016: Revista Médica de Chile
https://www.readbyqxmd.com/read/28057913/humoral-hypercalcemia-in-uterine-cancers-a-case-report-and-literature-review
#11
Vijeyaluxmy Motilal Nehru, Gwenalyn Garcia, Juan Ding, Fanyi Kong, Qun Dai
BACKGROUND Paraneoplastic hypercalcemia is a well-described complication associated with a variety of malignancies. However, its incidence in gynecological malignancies is low. CASE REPORT A 53-year-old woman presented with progressive abdominal distention and irregular vaginal bleeding of several weeks' duration. A contrast CT abdomen and pelvis was significant for a mass in the lower uterine/cervical region, multiple peritoneal and omental masses, enlarged pelvic and paraaortic lymph nodes, and large-volume ascites...
January 6, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28053375/prevalence-of-vitamin-d-deficiency-in-orthopaedic-patients-a-single-centre-study
#12
C P Pal, Harendra Kumar, Deepak Kumar, Vivek Mittal, Gaurav Deshwar, Danish Altaf, Sushant Verma
PURPOSE: Many recent reports demonstrated high rates of vitamin D deficiency in numerous segments of Indian population but no study has been reported so far from India, which focuses specifically on vitamin D status in orthopaedic patients. This study finds out the prevalence of vitamin D deficiency in orthopaedic patients in India. METHODS: Vitamin D levels of 1132 patients were measured from OPD and Emergency Department of S.N. Medical College, Agra from 1 November 2011 to 31 October 2013...
October 2016: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/28050798/effects-of-long-term-vitamin-d-supplementation-on-regression-and-metabolic-status-of-cervical-intraepithelial-neoplasia-a-randomized-double-blind-placebo-controlled-trial
#13
Zahra Vahedpoor, Mehri Jamilian, Fereshteh Bahmani, Esmat Aghadavod, Maryam Karamali, Maryam Kashanian, Zatollah Asemi
We are not aware of any study examining the effects of long term vitamin D administration on regression and metabolic status of patients with cervical intraepithelial neoplasia grade 1 (CIN1). This study was performed to evaluate the effects of long-term vitamin D administration on regression and metabolic status of patients with CIN1. This randomized, double-blind, placebo-controlled trial was performed among 58 women diagnosed with CIN1. CIN1 diagnosis was performed based on specific diagnostic procedures of biopsy, pathological diagnosis, and colposcopy...
January 3, 2017: Hormones & Cancer
https://www.readbyqxmd.com/read/28039046/bone-quality-assessment-as-measured-by-trabecular-bone-score-in-patients-with-end-stage-renal-disease-on-dialysis
#14
Maria P Yavropoulou, Vasilios Vaios, Maria Pikilidou, Ioannis Chryssogonidis, Melina Sachinidou, Symeon Tournis, Konstantinos Makris, Kalliopi Kotsa, Michalis Daniilidis, Afroditi Haritanti, Vassilios Liakopoulos
Patients with end-stage renal disease (ESRD) on maintenance hemodialysis (HD) exhibit osteoporosis and increased fracture risk. Dual-energy X-ray absorptiometry scan measurements and calculation of fracture risk assessment toll score underestimate fracture risk in these patients and do not estimate bone quality. Trabecular bone score (TBS) has been recently proposed as an indirect measure of bone microarchitecture. In this study, we investigated alterations of bone quality in patients with ESRD on HD, using TBS...
December 27, 2016: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28028727/vitamin-d-deficiency-in-older-adults-and-its-associated-factors-a-cross-sectional-analysis-of-the-mexican-health-and-aging-study
#15
María Fernanda Carrillo-Vega, Carmen García-Peña, Luis Miguel Gutiérrez-Robledo, Mario Ulises Pérez-Zepeda
: Vitamin D deficiency was common in older adults from a country with adequate sun exposure. The variables associated with this deficiency provide insight into the next steps needed to characterize older adults with this deficiency and to treat it accordingly. PURPOSE: The aim of this study was to describe the prevalence of and factors associated with vitamin D deficiency among Mexican older adults. METHODS: This was a secondary analysis of the last wave of the Mexican Health and Aging Study...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28027913/vitamin-d-and-cardiovascular-diseases-causality
#16
REVIEW
Sunil J Wimalawansa
Vitamin D regulates blood pressure, cardiac functions, and endothelial and smooth muscle cell functions, thus, playing an important role in cardiovascular health. Observational studies report associations between vitamin D deficiency with hypertension and cardiovascular-related deaths. Peer-reviewed papers were examined in several research databases as per the guidelines of the Preferred Reporting Items for Systematic Reviews, using key words that address the relationship between vitamin D and cardiovascular disease...
December 24, 2016: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/28027638/effects-of-bifidobacterium-animalis-lactis-hn019-dr10tm-inulin-and-micronutrient-fortified-milk-on-faecal-dr10tm-immune-markers-and-maternal-micronutrients-among-indonesian-pregnant-women
#17
Noroyono Wibowo, Saptawati Bardosono, Rima Irwinda
BACKGROUND AND OBJECTIVES: Maternal nutrition affects fetal growth and development. This study evaluates the effects of milk powder fortified with micronutrients, docosahexaenoic acid (DHA), a prebiotic, and probiotic Bifidobacterium animalis subsp. lactis HN019 DR10TM on the micronutrient status, as well as the presence of faecal probiotic and immune markers in pregnant women. METHODS AND STUDY DESIGN: This randomised, double- blind, placebo-controlled trial was conducted at Budi Kemuliaan and Cipto Mangunkusumo Hospital in Jakarta from 2013 to 2014...
December 2016: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28025639/evaluation-of-bone-metabolism-in-critically-ill-patients-using-ctx-and-pinp
#18
Alexandra Gavala, Konstantinos Makris, Anna Korompeli, Pavlos Myrianthefs
Background. Prolonged immobilization, nutritional and vitamin D deficiency, and specific drug administration may lead to significant bone resorption. Methods and Patients. We prospectively evaluated critically ill patients admitted to the ICU for at least 10 days. Demographics, APACHE II, SOFA scores, length of stay (LOS), and drug administration were recorded. Blood collections were performed at baseline and on a weekly basis for five consecutive weeks. Serum levels of PINP, β-CTx, iPTH, and 25(OH)vitamin D were measured at each time-point...
2016: BioMed Research International
https://www.readbyqxmd.com/read/28017448/25-hydroxyvitamin-d-concentrations-asthma-and-eczema-in-childhood-the-generation-r-study
#19
Ilse I M Tromp, Oscar H Franco, Edith H van den Hooven, Annemieke C Heijboer, Vincent W V Jaddoe, Liesbeth Duijts, Johan C de Jongste, Henriëtte A Moll, Jessica C Kiefte-de Jong
BACKGROUND & AIMS: A role of vitamin D in the development of respiratory and allergic disease in children remains unclear. It may be likely that vitamin D has an effect on airway inflammation, but only few studies examined the effect in children. We aimed to examine whether serum 25-hydroxyvitamin D (25(OH) vitamin D) concentrations are associated with the fraction of exhaled nitric oxide (FeNO), airway interrupter resistance (Rint), physician diagnosed asthma ever, wheezing and eczema in a population-based cohort study in 6 year old children...
December 8, 2016: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28002913/pregnancy-associated-osteoporosis-pao-with-multiple-vertebral-fragility-fractures-diagnosis-and-treatment-in-a-young-primigravid-woman
#20
E Pola, D Colangelo, L A Nasto, V Pambianco, G Autore, V M Formica, G Maccauro
PAO is an uncommon condition affecting pregnant women during last trimester or early post-delivery period; it is often asymptomatic or presents with pain related to some acute fragility fractures. The diagnosis is often delayed or missed, the etiology remains unknown and no guidelines about treatment have been published. We present one case of PAO in a 33-year-old primigravid woman presenting acute worsening back pain. Our patient was treated with a TLSO brace, oral 25 (OH)-vitamin D supplementation and Teriparatide for 6 months...
October 2016: Journal of Biological Regulators and Homeostatic Agents
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