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https://www.readbyqxmd.com/read/28445880/heating-of-newborn-infants-due-to-blue-light-emitting-diode-fibreoptic-phototherapy-pads
#1
Pei Ling Ng, Tony Carlisle, Marleesa Ly, Scott Adam Morris
BACKGROUND: Surface temperatures of fibreoptic phototherapy pads using a high intensity blue light-emitting diode (LED) light source have not been studied. OBJECTIVES: The aim of this study was to measure the temperature of LED fibreoptic phototherapy pads during phototherapy in a bench-top study, and to determine temperature effects on babies during phototherapy. METHODS: A commercially available LED fibreoptic phototherapy system was tested...
April 27, 2017: Neonatology
https://www.readbyqxmd.com/read/28445697/influence-of-maturation-on-in-vivo-tissue-to-plasma-partition-coefficients-for-cis-and-trans-permethrin
#2
Manoj Amaraneni, Jing Pang, James V Bruckner, Srinivasa Muralidhara, Tanzir B Mortuza, Darren Gullick, Shirin Hooshfar, Catherine A White, Brian S Cummings
Permethrin, the most widely used household insecticide in the U.S., is marketed as a mixture of its cis (CIS) and trans (TRANS) isomers. The major objective of this investigation was to develop and utilize a reliable approach to determine in vivo partition coefficients (PCs) for CIS and TRANS in immature and adult Sprague-Dawley rats. Adult, postnatal day (PND) 21 and PND 15 rats were infused with environmentally relevant concentrations of CIS or TRANS via a s.c. osmotic pump for 48 or 72 h. The adult and PND 21 rats also received an oral loading dose...
April 23, 2017: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28445376/defining-temporal-hairline-landmarks
#3
Purushottam A Nagarkar, Jonathan Cheng
Brow dermoids are benign pediatric neoplasms. Endoscopic resection requires incisions placed within the temporal hairline, which is often difficult to reliably locate in infants. The authors studied adult and pediatric patients to define the location of the hairline in relationship to simple facial landmarks. Adult and pediatric patients who were seen in preoperative consultation for facial surgical procedures were identified and included in the study. Patients with a history of facial trauma, surgery, or congenital anomalies were excluded...
May 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28445302/cholestasis-caused-by-panhypopituitarism-and-acquired-cytomegalovirus-infection-in-a-2-month-old-male-infant-a-case-report
#4
U Chan, Wai-Tao Chan, Wei-Hsin Ting, Che-Sheng Ho, Hsi-Che Liu, Hung-Chang Lee
RATIONALE: Septo-optic dysplasia (SOD) is a rare congenital disorder that may cause jaundice in infants. However, it is usually prone to neglect and misdiagnosis in infants with cholestasis because endocrine disorder such as panhypopituitarism is rare in the cause of infantile cholestasis. We report a case of SOD concurrent with acquired cytomegalovirus (CMV) infection, who presented with prolonged jaundice as the first clinical sign. PATIENT CONCERNS: The patient was a 2-month-old male infant who presented with cholestasis, combined with fever and panhypopituitarism...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28445284/appendiceal-foreign-body-in-an-infant
#5
Min Lee, Soon Chul Kim
RATIONALE FOR THIS CASE REPORT: Many children are hospitalized because of foreign body ingestion. In such circumstances, the gastroenterologist must consider the timing of ingestion; the size, type, and location of the object ingested; and the patient's symptoms. But appendiceal foreign body in infant is very rare. PATIENT CONCERNS: A 12-month-old boy visited because of swallowing small objects 2 weeks ago. Three small beads were found in the right lower quadrant on abdominal radiography...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28445267/different-clinical-presentations-of-choledochal-cyst-among-infants-and-older-children-a-10-year-retrospective-study
#6
Davoud Badebarin, Saeid Aslanabadi, Amir Teimouri-Dereshki, Masoud Jamshidi, Tuba Tarverdizadeh, Kaveh Shad, Kamyar Ghabili, Ghazal Khajir
Choledochal cyst is a rare and often benign congenital cystic dilation throughout the biliary tree. Due to the benign nature of choledochal cyst among early-diagnosed patients, the clinical assumption and diagnosis seem to be of utmost significance. Therefore, we sought to assess different clinical manifestations of choledochal cyst and relevant laboratory findings in infants and older children.Retrospectively, medical records of all patients with the diagnosis of choledochal cyst between 2005 and 2015 were reviewed...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28445189/proton-pump-inhibitor-responsive-esophageal-eosinophilia-still-a-valid-diagnosis
#7
Javier Molina-Infante, Pedro L Gonzalez-Cordero, Alfredo J Lucendo
PURPOSE OF REVIEW: To update rapidly evolving concepts regarding the controversial entity of 'proton pump inhibitor (PPI)-responsive esophageal eosinophilia,' referring to patients with clinical, endoscopic and histologic features of eosinophilic esophagitis (EoE) who achieve remission on PPI therapy. RECENT FINDINGS: Up to half of pediatric and adult patients with typical EoE symptoms and histology achieve clinico-pathologic remission on PPI therapy, irrespective of whether esophageal pH monitoring demonstrates abnormal acid reflux...
April 25, 2017: Current Opinion in Gastroenterology
https://www.readbyqxmd.com/read/28444819/antenatal-maternal-hepatitis-b-care-is-a-predictor-of-timely-perinatal-administration-of-hepatitis-b-immunoglobulin
#8
Suong Tt Le, Lukas Sahhar, Stephanie Spring, William Sievert, Anouk T Dev
BACKGROUND: Mother-to-child transmission (MTCT) of hepatitis B virus continues to occur despite universal recommendations for neonatal immune prophylaxis therapy (IPT) and infant vaccination. AIM: To characterise the risk factors for failure to provide timely IPT and completion of the infant hepatitis B vaccination schedule for children born to mothers with Chronic Hepatitis B (CHB). METHODS: We conducted a retrospective cohort study to assess compliance with universal guidelines for neonatal IPT for children born to CHB mothers at Monash Health, Australia from 2008 to 2013...
April 26, 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/28444729/benefits-of-rituximab-as-a-second-line-treatment-for-autoimmune-haemolytic-anaemia-in-children-a-prospective-french-cohort-study
#9
Stéphane Ducassou, Guy Leverger, Helder Fernandes, Hervé Chambost, Yves Bertrand, Corinne Armari-Alla, Brigitte Nelken, Fabrice Monpoux, Corinne Guitton, Thierry Leblanc, Alain Fisher, Odile Lejars, Eric Jeziorski, Fanny Fouissac, Patrick Lutz, Marlène Pasquet, Isabelle Pellier, Christophe Piguet, Philippe Vic, Sophie Bayart, Aude Marie-Cardine, Marc Michel, Yves Perel, Nathalie Aladjidi
Childhood autoimmune haemolytic anaemia (AIHA) requires second-line immunosuppressive therapy in 30-50% of cases. It appears that rituximab is indicated in such circumstances. This prospective national study reports the practice, efficacy and tolerance of rituximab in children with isolated AIHA and AIHA in the setting of Evans syndrome (ES). Sixty-one children were given rituximab between 2000 and 2014. The median interval from diagnosis to rituximab was 9·9 [interquartile range (IQR) 1·6-28·5] months. Forty-six patients responded (75%) and the 6-year relapse-free survival (RFS) was 48%...
April 26, 2017: British Journal of Haematology
https://www.readbyqxmd.com/read/28444697/population-pharmacokinetics-of-dexmedetomidine-in-infants
#10
Rachel G Greenberg, Huali Wu, Matthew Laughon, Edmund Capparelli, Stevie Rowe, Kanecia O Zimmerman, P Brian Smith, Michael Cohen-Wolkowiez
Despite limited pharmacokinetic (PK) data, dexmedetomidine is increasingly being used off-label for sedation in infants. We aimed to characterize the developmental PK changes of dexmedetomidine during infancy. In this open-label, single-center PK study of dexmedetomidine in infants receiving dexmedetomidine per clinical care, ≤10 blood samples per infant were collected. A set of structural PK models and residual error models were explored using nonlinear mixed-effects modeling in NONMEM. Covariates including postmenstrual age (PMA), serum creatinine, and recent history of cardiac surgery requiring cardiopulmonary bypass were investigated for their influence on PK parameters...
April 25, 2017: Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28444656/subacute-myocarditis-associated-with-bocavirus-infection-in-an-8-week-old-infant
#11
Hannes Sallmon, ElenaJuan Lopez, Sven Weber, Susanne Herrmann, Felix Berger, Guido Haverkämper
No abstract text is available yet for this article.
March 2017: Klinische Pädiatrie
https://www.readbyqxmd.com/read/28444557/overview-on-the-current-status-of-zika-virus-pathogenesis-and-animal-related-research
#12
REVIEW
Shashank S Pawitwar, Supurna Dhar, Sneham Tiwari, Chet Raj Ojha, Jessica Lapierre, Kyle Martins, Alexandra Rodzinski, Tiyash Parira, Iru Paudel, Jiaojiao Li, Rajib Kumar Dutta, Monica R Silva, Ajeet Kaushik, Nazira El-Hage
There is growing evidence that Zika virus (ZIKV) infection is linked with activation of Guillan-Barré syndrome (GBS) in adults infected with the virus and microcephaly in infants following maternal infection. With the recent outpour in publications by numerous research labs, the association between microcephaly in newborns and ZIKV has become very apparent in which large numbers of viral particles were found in the central nervous tissue of an electively aborted microcephalic ZIKV-infected fetus. However, the underlying related mechanisms remain poorly understood...
April 25, 2017: Journal of Neuroimmune Pharmacology: the Official Journal of the Society on NeuroImmune Pharmacology
https://www.readbyqxmd.com/read/28444460/hydrocephalus-a-rare-initial-manifestation-of-sporadic-intramedullary-hemangioblastoma-intramedullary-hemangioblastoma-presenting-as-hydrocephalus
#13
Barbara Albuquerque Morais, Daniel Dante Cardeal, Renan Ribeiro E Ribeiro, Fernando Pereira Frassetto, Fernanda Goncalves Andrade, Hamilton Matushita, Manoel Jacobsen Teixeira
BACKGROUND: Intramedullary hemangioblastomas are rare benign vascular tumors, infrequent in pediatric patients. Clinical symptoms vary according to the age of presentation, tumor size, location, and concomitant syringomyelia. This is the second reported case of hemangioblastoma presenting with acute hydrocephalus. CASE PRESENTATION: A 3-month-old infant with acute hydrocephalus was asymptomatic after a ventriculoperitoneal shunt was placed. She returned 3 months later with irritability, acute paraplegia, and respiratory distress...
April 25, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28444360/role-of-early-onset-neutropenia-in-development-of-candidemia-in-premature-infants
#14
Nermin Ramy, Mohamed Hashim, Heba Abou Hussein, Happy Sawires, Maha Gaafar, Ayat El Maghraby
Background: The aim of the study was to assess the effect of early-onset neutropenia (EON) on the development of candidemia in premature infants and evaluate other risk factors. Materials and Methods: This prospective study was carried out in a neonatal intensive care unit of Cairo University Hospital. Fifty neutropenic premature infants were matched to 50 non-neutropenics. Subjects were then regrouped into candidemics and non-candidemics to study other risk factors such as central venous catheters, mechanical ventilation, parenteral nutrition, drugs as corticosteroids and others...
April 24, 2017: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/28444286/screening-for-preeclampsia-us-preventive-services-task-force-recommendation-statement
#15
Kirsten Bibbins-Domingo, David C Grossman, Susan J Curry, Michael J Barry, Karina W Davidson, Chyke A Doubeni, John W Epling, Alex R Kemper, Alex H Krist, Ann E Kurth, C Seth Landefeld, Carol M Mangione, William R Phillips, Maureen G Phipps, Michael Silverstein, Melissa A Simon, Chien-Wen Tseng
Importance: Preeclampsia affects approximately 4% of pregnancies in the United States. It is the second leading cause of maternal mortality worldwide and may lead to serious maternal complications, including stroke, eclampsia, and organ failure. Adverse perinatal outcomes for the fetus and newborn include intrauterine growth restriction, low birth weight, and stillbirth. Many of the complications associated with preeclampsia lead to early induction of labor or cesarean delivery and subsequent preterm birth...
April 25, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28444285/preeclampsia-screening-evidence-report-and-systematic-review-for-the-us-preventive-services-task-force
#16
Jillian T Henderson, Jamie H Thompson, Brittany U Burda, Amy Cantor
Importance: Preeclampsia is a complex disease of pregnancy with sometimes serious effects on maternal and infant morbidity and mortality. It is defined by hypertension after 20 weeks' gestation and proteinuria or other evidence of multisystem involvement. Objective: To systematically review the benefits and harms of preeclampsia screening and risk assessment for the US Preventive Services Task Force. Data Sources: MEDLINE, PubMed, and Cochrane Central Register of Controlled Trials databases from 1990 through September 1, 2015...
April 25, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28444240/non-specific-effects-of-oral-polio-vaccine-on-diarrheal-burden-and-etiology-among-bangladeshi-infants
#17
Alexander Upfill-Brown, Mami Taniuchi, James A Platts-Mills, Beth Kirkpatrick, Stacey L Burgess, M Steven Oberste, William Weldon, Eric Houpt, Rashidul Haque, K Zaman, William A Petri
Background: As the global polio eradication initiative prepares to cease use of oral polio vaccine (OPV) in 2020, there is increasing interest in understanding if oral vaccination provides non-specific immunity to other infections so that the consequences of this transition can be effectively planned for and mitigated. Methods: Data was collected from infants in an urban slum in Bangladesh (Mirpur, Dhaka) as part of the PROVIDE study. Following vaccination with tOPV at 6,10, and 14 weeks, infants were randomly assigned to receive tOPV (n=315) or IPV (n=299) at 39 weeks...
April 24, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28444232/co-trimoxazole-prophylaxis-asymptomatic-malaria-parasitemia-and-infectious-morbidity-in-hiv-exposed-uninfected-infants-in-malawi-the-ban-study
#18
Nicole L Davis, Jeffrey Wiener, Jonathan J Juliano, Linda Adair, Charles S Chasela, Dumbani Kayira, Michael G Hudgens, Charles van der Horst, Denise J Jamieson, Athena P Kourtis
Background: HIV-exposed infants are disproportionately at risk of morbidity and mortality compared with their HIV-unexposed counterparts. The role of co-trimoxazole preventive therapy (CPT) in reducing leading causes of infectious morbidity is unclear. Methods: We used data from the Breastfeeding, Antiretrovirals and Nutrition (BAN) clinical trial (conducted 2004-2010, Malawi) to assess the association of 1) CPT and 2) asymptomatic malaria parasitemia with respiratory and diarrheal morbidity in infants...
April 21, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28444157/risk-of-congenital-syphilis-following-treatment-of-maternal-syphilis-results-of-a-congenital-syphilis-control-program-in-china
#19
Fu-Chang Hong, Xiao-Bing Wu, Fan Yang, Li-Na Lan, Yang Guan, Chun-Lai Zhang, Tie-Jian Feng, Ying-Zhou Yang, Yue-Ping Yin, Wei-Ye Yu, Xiang-Sheng Chen
Background.: Early screening for syphilis among pregnant women and the effective treatment of maternal syphilis is fundamental to prevent congenital syphilis (CS). Methods.: We obtained data from the Shenzhen Program for Prevention of Congenital Syphilis (SPPCS) and estimated incidence rates of CS among infants born to syphilis-seropositive women treated with different regimens or untreated for maternal syphilis. Results.: 4746 matched cases of syphilis-seropositive mothers and their infants were included for analyses and 162 infants were diagnosed with CS, providing an overall incidence of 3...
April 21, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28443965/prognosis-determinants-after-cardioverter-defibrillators-implantation-in-brazil
#20
Arn Migowski, Regina Maria de Aquino Xavier, Katia Regina da Silva, Caio Marcos de Moraes Albertini, Elizabeth Sartori Crevelari, Eduardo Infante Januzzi de Carvalho, Alfredo Inácio Fiorelli, Martino Martinelli Filho, Roberto Costa
No abstract text is available yet for this article.
March 2017: Arquivos Brasileiros de Cardiologia
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