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https://www.readbyqxmd.com/read/27899861/echocardiographic-follow-up-of-patent-foramen-ovale-and-the-factors-affecting-spontaneous-closure
#1
Ali Yildirim, Alperen Aydin, Tevfik Demir, Fatma Aydin, Birsen Ucar, Zubeyir Kilic
BACKGROUND: The aim of the present study was to evaluate the echocardiographic follow-up of patent foramen ovale, which is considered a potential etiological factor in various diseases, and to determine the factors affecting spontaneous closure. METHODS: Between January 2000 and June 2012, records of 918 patients with patent foramen ovale were retrospectively reviewed. Patency of less than 3 mm around the fossa ovalis is called patent foramen ovale. Patients with cyanotic congenital heart diseases, severe heart valve disorders and severe hemodynamic left to right shunts were excluded from the study...
November 2016: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/27861432/the-association-between-preoperative-hemoglobin-a1c-and-postoperative-glycemic-variability-on-30-day-major-adverse-outcomes-following-isolated-cardiac-valvular-surgery
#2
Amit Bardia, Kamal Khabbaz, Ariel Mueller, Priyam Mathur, Victor Novack, Daniel Talmor, Balachundhar Subramaniam
BACKGROUND: Preoperative hemoglobin A1c (HbA1c) and postoperative glycemic variability predict major adverse events (MAEs) after coronary artery bypass grafting in a protocolized glycemic control setting. However, the influence of preoperative HbA1c and postoperative glycemic variability in isolated cardiac valvular surgery is unknown. In this study, we sought to establish (a) whether preoperative HbA1c could identify patients at increased risk of MAEs and (b) whether postoperative glycemic variability was associated with MAEs after isolated cardiac valvular surgery...
November 17, 2016: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/27751262/congenitally-unguarded-tricuspid-valve-orifice-with-right-ventricular-apical-isolation-in-an-adult
#3
Jagdish C Mohan, Madhu Shukla, Vishwas Mohan, Arvind Sethi
Congenitally unguarded tricuspid valve (TV) orifice, a variant of TV dysplasia, is a rare malformation with protean manifestations. This report describes a symptomatic adult male with gross right heart failure and atrial fibrillation, who was found to have an unguarded TV orifice with isolation of the trabecular apical cavity of the right ventricle (RV) and muscular ridges separating outflow tract (forme-fruste of the double-chambered RV). The right ventricular outflow tract remained patent.
September 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/27646067/-imaging-in-structural-heart-disease-impact-on-interventional-therapy
#4
A Schmermund, J Eckert, S N Schelle, H Eggebrecht
For the treatment of structural heart disease, current options in the catheterization laboratory include MitraClip® implantation for treating severe mitral regurgitation, transcatheter aortic valve implantation (TAVI), closure of a patent foramen ovale (PFO) and occlusion of the left atrial appendage (LAA). These treatment options are based on a precise diagnosis provided by modern cardiac imaging, which is indispensable for treatment recommendations. Its importance for supporting the invasive procedures in the catheterization laboratory is less well known...
November 2016: Herz
https://www.readbyqxmd.com/read/27543649/endoscopic-atrioventricular-valve-surgery-in-adults-with-difficult-to-access-uncorrected-congenital-chest-wall-deformities
#5
Johan van der Merwe, Filip Casselman, Bernard Stockman, Yvette Vermeulen, Ivan Degrieck, Frank Van Praet
OBJECTIVES: This study presents the first report on in-hospital and long-term outcomes of endoscopic port access atrioventricular valve surgery (EPAAVVS) in adult patients with uncorrected congenital chest wall deformities (CCWDs). METHODS: Our current surgical team performed EPAAVVS in 7 consecutive adult patients (mean age 51.3 ± 16.4 years, 14.3% female, 50% older than 60 years, mean EuroSCORE II 0.8 ± 0.1%) with uncorrected CCWDs between 1 November 2009 and 30 November 2015...
August 19, 2016: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/27452334/whole-exome-sequencing-familial-genomic-triangulation-and-systems-biology-converge-to-identify-a-novel-nonsense-mutation-in-tab2-encoded-tgf-beta-activated-kinase-1-in-a-child-with-polyvalvular-syndrome
#6
Jaeger P Ackerman, John A Smestad, David J Tester, Muhammad Y Qureshi, Beau A Crabb, Nancy J Mendelsohn, Michael J Ackerman
OBJECTIVE: To use whole exome sequencing (WES) of a family trio to identify a genetic cause for polyvalvular syndrome. METHODS AND RESULTS: A male child was born with mild pulmonary valve stenosis and mild aortic root dilatation, and an atrial septal defect, ventricular septal defect, and patent ductus arteriosus that were closed surgically. Subsequently, the phenotype of polyvalvular syndrome with involvement of both semilunar and both atrioventricular valves emerged...
September 2016: Congenital Heart Disease
https://www.readbyqxmd.com/read/27418595/utilization-of-whole-exome-sequencing-to-identify-causative-mutations-in-familial-congenital-heart-disease
#7
Stephanie LaHaye, Don Corsmeier, Madhumita Basu, Jessica L Bowman, Sara Fitzgerald-Butt, Gloria Zender, Kevin Bosse, Kim L McBride, Peter White, Vidu Garg
BACKGROUND: Congenital heart disease (CHD) is the most common type of birth defect with family- and population-based studies supporting a strong genetic cause for CHD. The goal of this study was to determine whether a whole exome sequencing (WES) approach could identify pathogenic-segregating variants in multiplex CHD families. METHODS AND RESULTS: WES was performed on 9 kindreds with familial CHD, 4 with atrial septal defects, 2 with patent ductus arteriosus, 2 with tetralogy of Fallot, and 1 with pulmonary valve dysplasia...
August 2016: Circulation. Cardiovascular Genetics
https://www.readbyqxmd.com/read/27378604/interventional-cardiology-where-real-life-and-science-do-not-necessarily-meet
#8
REVIEW
Bernhard Meier
Evidence-based diagnosis, decision-making, and therapy appear a must these days. Generating and publishing evidence is a tedious job according to ever new and tightened research practice regulations. Rules will never prevent the typical human behaviour from showing the new thing to be shinier and the old thing dustier than they really are. The medical community is solicited to concoct a meal that is gullible for patients, authorities, and third-party payers out of the available evidence (after applying some conversion factors correcting the common bias of the researchers), anticipation of what will be the evidence tomorrow, common sense, and digested experience...
July 7, 2016: European Heart Journal
https://www.readbyqxmd.com/read/27316488/circulating-level-of-regulatory-t-cells-in-rheumatic-heart-disease-an-observational-study
#9
Saibal Mukhopadhyay, Saurabh Varma, H N Mohan Kumar, Jamal Yusaf, Mayank Goyal, Vimal Mehta, Sanjay Tyagi
BACKGROUND: The regulatory T cell (Treg) is essential for prevention of autoimmunity. In a preliminary study, we showed significant deficiency of Tregs (CD4CD25 T cells) in rheumatic heart disease (RHD) patients (an autoimmune disease), but the markers used could not reliably differentiate Treg from nonregulatory conventional T cells (Tcon). The study aim was to reassess the level of circulatory Tregs by using more specific markers. METHODS: 70 adults of RHD and 35 controls were studied...
May 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/27293526/a-constellation-of-cardiac-anomalies-beyond-shone-s-complex
#10
Neeraj K Ganju, Arvind Kandoria, Suresh Thakur, Sunite A Ganju
Shone's anomaly is a very rare congenital cardiac malformation characterized by four serial obstructive lesions of the left side of the heart (i) Supravalvular mitral membrane (ii) parachute mitral valve (iii) muscular or membranous subaortic stenosis and (iv) coarctation of aorta. We report a unique presentation of Shone's complex in a 14-year-old adolescent male. In addition to the four characteristic lesions the patient had bicuspid aortic valve, aneurysm of sinus of valsalva, patent ductus arteriosus, ventricular septal defect, persistent left superior vena cava opening into coronary sinus and severe pulmonary artery hypertension...
January 2016: Heart Views: the Official Journal of the Gulf Heart Association
https://www.readbyqxmd.com/read/27277596/a-review-of-the-key-clinical-trials-of-2015-results-and-implications
#11
Claire McCune, Peter McKavanagh, Ian B A Menown
INTRODUCTION: Multiple significant, potentially practice changing clinical trials in cardiology have been conducted and subsequently presented throughout the past year. METHODS: In this paper, the authors have reviewed and contextualized significant cardiovascular clinical trials presented at major international conferences of 2015 including American College of Cardiology, European Association for Percutaneous Cardiovascular Interventions, American Diabetes Association, European Society of Cardiology, Transcatheter Cardiovascular Therapeutics, Heart Rhythm Congress, and the American Heart Association Scientific Sessions...
June 8, 2016: Cardiology and Therapy
https://www.readbyqxmd.com/read/27256439/-clinical-treatment-of-infective-endocarditis-with-vegetations-in-pregnant-women-and-the-outcomes-of-gestation
#12
L Chu, J Zhang, Y N Li, X Meng, Y Y Liu
OBJECTIVE: To investigate the clinical treatment of infective endocarditis with vegetations in pregnant women and the outcomes of the gestation. METHODS: Nine cases of pregnant women diagnosed as infective endocarditis with vegetations in Beijing Anzhen Hospital, Capital Medical University from January 2001 to October 2015 were enrolled in retrospective analysis. Consultations were held by doctors from department of obstetrics, anesthesiology, cardiology, cardial surgery and extracorporeal circulation to decide the individualized treatment plan for the 9 cases of pregnant women after admissions...
May 25, 2016: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/27152142/influence-of-hospital-volume-and-outcomes-of-adult-structural-heart-procedures
#13
REVIEW
Sidakpal S Panaich, Nilay Patel, Shilpkumar Arora, Nileshkumar J Patel, Samir V Patel, Chirag Savani, Vikas Singh, Rajesh Sonani, Abhishek Deshmukh, Michael Cleman, Abeel Mangi, John K Forrest, Apurva O Badheka
Hospital volume is regarded amongst many in the medical community as an important quality metric. This is especially true in more complicated and less commonly performed procedures such as structural heart disease interventions. Seminal work on hospital volume relationships was done by Luft et al more than 4 decades ago, when they demonstrated that hospitals performing > 200 surgical procedures a year had 25%-41% lower mortality than those performing fewer procedures. Numerous volume-outcome studies have since been done for varied surgical procedures...
April 26, 2016: World Journal of Cardiology
https://www.readbyqxmd.com/read/27096525/spectrum-of-cardiac-lesions-associated-with-isolated-cleft-mitral-valve-and-their-impact-on-therapeutic-choices
#14
Ayoub El Hammiri, Abdenasser Drighil, Sanaa Benhaourech
BACKGROUND: Isolated cleft mitral valve (ICMV) may occur alone or in association with other congenital heart lesions. The aim of this study was to describe the profile of cardiac lesions associated with ICMV and their potential impact on therapeutic management. METHODS: We conducted a descriptive study with data retrieved from the Congenital Heart Disease (CHD) single-center registry of our institution, including patients with ICMV registered between December 2008 and November 2014...
May 2016: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/27090167/complete-antegrade-transapical-deployment-of-a-branched-aortic-arch-endograft-a-porcine-feasibility-study
#15
Sabine Wipper, Christina Lohrenz, Jan F Kersten, Mohamad Marwan Akkra, Nikos Tsilimparis, Christian Detter, Yskert von Kodolitsch, Axel Larena-Avellaneda, Eike Sebastian Debus, Tilo Kölbel
PURPOSE: To describe and prove the concept of a technique for complete transapical deployment of a single-branch aortic arch endograft in a porcine model. METHODS: Eight domestic pigs underwent antegrade transapical delivery of a single-branch arch endograft, including a mating stent-graft to the innominate artery. Technical feasibility, operating time, radiation parameters, and hemodynamic changes were studied according to a standardized protocol during baseline (T0), after establishing the transapical access and through-and-through wire (T1), and after stent-graft deployment (T2)...
June 2016: Journal of Endovascular Therapy
https://www.readbyqxmd.com/read/26926291/therapeutic-utilities-of-pediatric-cardiac-catheterization
#16
REVIEW
Giannis A Moustafa, Argyrios Kolokythas, Konstantinos Charitakis, Dimitrios V Avgerinos
In an era when less invasive techniques are favored, therapeutic cardiac catheterization constantly evolves and widens its spectrum of usage in the pediatric population. The advent of sophisticated devices and well-designed equipment has made the management of many congenital cardiac lesions more efficient and safer, while providing more comfort to the patient. Nowadays, a large variety of heart diseases are managed with transcatheter techniques, such as patent foramen ovale, atrial and ventricular septal defects, valve stenosis, patent ductus arteriosus, aortic coarctation, pulmonary artery and vein stenosis and arteriovenous malformations...
2016: Current Cardiology Reviews
https://www.readbyqxmd.com/read/26897194/decreased-hemolysis-and-improved-hemodynamic-performance-of-synchronized-bileaflet-mechanical-valve
#17
COMPARATIVE STUDY
Chau-Chang Chou, Te-Chun Wu, Hong-Yen Liang, Yi-Chih Chow, Chi-Hsiao Yeh, Wen-Jin Cherng
PURPOSE: This study compared the performance of a newly patented synchronized valve (SV) with that of a commercially available (CAV) bileaflet mechanical heart valve. DESCRIPTION: A high-speed camera was used to record the leaflet kinematics of the SV vs the CAV along the flow channel. Transvalvular energy loss, effective orifice area, and hemolysis ratios were obtained using a mock circulatory system at two fixed pulse rates and at various cardiac outputs with a fixed aortic pressure...
March 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/26838664/beating-heart-minimally-invasive-mitral-valve-surgery-in-patients-with-patent-coronary-bypass-grafts
#18
Aly Ghoneim, Ismail Bouhout, Amine Mazine, William Fortin, Ismail El-Hamamsy, Hugue Jeanmart, Michel Pellerin, Denis Bouchard
BACKGROUND: Redo mitral valve surgery in patients with patent coronary bypass grafts carries a risk of graft injury and postoperative bleeding. We compare early results of reoperative minimally invasive on-pump beating heart mitral valve surgery (OPBMS) via mini thoracotomy vs the results of standard sternotomy mitral valve surgery (SSMS) in the presence of patent coronary bypass grafts. METHODS: Between 2009 and 2015, 12 patients underwent OPBMS through a right mini thoracotomy and 6 patients underwent SSMS...
August 2016: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/26812828/retrospective-analysis-of-co-occurrence-of-congenital-aortic-stenosis-and-pulmonary-artery-stenosis-in-dogs
#19
M Kander, U Pasławska, M Staszczyk, A Cepiel, R Pasławski, G Mazur, A Noszczyk-Nowak
The study has focused on the retrospective analysis of cases of coexisting congenital aortic stenosis (AS) and pulmonary artery stenosis (PS) in dogs. The research included 5463 dogs which were referred for cardiological examination (including clinical examination, ECG and echocardiography) between 2004 and 2014. Aortic stenosis and PS stenosis were detected in 31 dogs. This complex defect was the most commonly diagnosed in Boxers - 7 dogs, other breeds were represented by: 4 cross-breed dogs, 2 Bichon Maltais, 3 Miniature Pinschers, 2 Bernese Mountain Dogs, 2 French Bulldogs, and individuals of following breeds: Bichon Frise, Bull Terrier, Czech Wolfdog, German Shepherd, Hairless Chinese Crested Dog, Miniature Schnauzer, Pug, Rottweiler, Samoyed, West Highland White Terrier and Yorkshire Terrier...
2015: Polish Journal of Veterinary Sciences
https://www.readbyqxmd.com/read/26786543/nationwide-hospitalization-trends-in-adult-congenital-heart-disease-across-2003-2012
#20
Shikhar Agarwal, Karan Sud, Venu Menon
BACKGROUND: We aimed to assess trends in hospitalization, outcomes, and resource utilization among patients admitted with adult congenital heart disease (ACHD). METHODS AND RESULTS: We used the 2003-2012 US Nationwide Inpatient Sample for this study. All admissions with an ACHD were identified using standard ICD codes. Resource utilization was assessed using length of stay, invasive procedure utilization, and cost of hospitalization. There was a significant increase in the number of both simple (101%) as well as complex congenital heart disease (53%)-related admissions across 2003-2012...
January 2016: Journal of the American Heart Association
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