keyword
MENU ▼
Read by QxMD icon Read
search

iMRI

keyword
https://www.readbyqxmd.com/read/29044370/the-ecology-and-epidemiology-of-ross-river-and-murray-valley-encephalitis-viruses-in-western-australia-examples-of-one-health-in-action
#1
John S Mackenzie, Michael D A Lindsay, David W Smith, Allison Imrie
Arboviruses are maintained and transmitted through an alternating biological cycle in arthropods and vertebrates, with largely incidental disease in humans and animals. As such, they provide excellent examples of One Health, as their health impact is inextricably linked to their vertebrate hosts, their arthropod vectors and the environment. Prevention and control requires a comprehensive understanding of these interactions, and how they may be effectively and safely modified. This review concentrates on human disease due to Ross River and Murray Valley encephalitis viruses, the two major arboviral pathogens in Australia...
June 1, 2017: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28973637/complications-of-head-immobilization-devices-in-children-contact-mechanics-and-analysis-of-a-single-institutional-experience
#2
Mohamed A Zaazoue, Mostafa Bedewy, Liliana C Goumnerova
BACKGROUND: Head immobilization devices (HIDs) are a staple of neurosurgical procedures, including in the intraoperative magnetic resonance imaging (iMRI) operating rooms (ORs) where material modifications were necessary for compatibility with the magnets utilized. OBJECTIVE: To present the experience in this OR environment and discuss the multifactorial nature of the observed adverse events. METHODS: A retrospective chart review was performed, utilizing the Department of Neurosurgery and iMRI OR databases to identify patients who suffered complications related to HIDs between November 2007 and March 2016...
June 20, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28921173/maximizing-safe-resections-the-roles-of-5-aminolevulinic-acid-and-intraoperative-mr-imaging-in-glioma-surgery-review-of-the-literature
#3
REVIEW
Eric Suero Molina, S Schipmann, W Stummer
Malignant glioma surgery involves the challenge of preserving the neurological status of patients harboring these lesions while pursuing a maximal tumor resection, which is correlated with overall and progression-free survival. Presently, several tools exist for assisting neurosurgeons in visualizing malignant tissue. Fluorescence-guided surgery (FGS) with 5-aminolevulinic acid (5-ALA) has increasingly been used during the last decade for identifying malignant glioma. Intraoperative magnetic resonance imaging (iMRI), first introduced in the mid-1990s, is being evaluated as a further tool to maximize the extent of resection...
September 18, 2017: Neurosurgical Review
https://www.readbyqxmd.com/read/28917282/interventional-mri-guided-deep-brain-stimulation-lead-implantation
#4
REVIEW
Philip S Lee, Robert Mark Richardson
Current knowledge of the functional anatomy of the subthalamic nucleus and globus pallidus, discovered through microelectrode recording and postoperative imaging, justifies purely anatomic targeting for deep brain stimulation (DBS). Interventional MRI (iMRI)-DBS is more anatomically accurate than traditional awake procedures and has similar clinical outcomes without increased risk or increased operative times. iMRI lead implantation allows patients to receive DBS therapy who cannot tolerate or do not agree to undergo an awake procedure...
October 2017: Neurosurgery Clinics of North America
https://www.readbyqxmd.com/read/28917279/imri-during-transsphenoidal-surgery
#5
REVIEW
Prashant Chittiboina
A variety of intraoperative MRI (iMRI) systems are in use during transsphenoidal surgery (TSS). The variations in iMRI systems include field strengths, magnet configurations, and room configurations. Most studies report that the primary utility of iMRI during TSS lies in detecting resectable tumor residuals following maximal resection with conventional technique. Stereotaxis, neuronavigation, and complication avoidance/detection are enhanced by iMRI use during TSS. The use of iMRI during TSS can lead to increased extent of resection for large tumors...
October 2017: Neurosurgery Clinics of North America
https://www.readbyqxmd.com/read/28917277/intraoperative-mri-and-maximizing-extent-of-resection
#6
REVIEW
Ganesh Rao
Intraoperative MRI (iMRI) is a neurosurgical adjunct used to maximize the removal of glioma, the most common primary brain tumor. Increased extent of resection of gliomas has been shown to correlate with longer survival times. iMRI units are variable in design and magnet strength, which can affect patient selection and image quality. Multiple studies have shown that surgical resection of gliomas using iMRI results in increased extent of resection and survival time. Level II evidence supports the use of iMRI in the surgical treatment of glioma...
October 2017: Neurosurgery Clinics of North America
https://www.readbyqxmd.com/read/28917276/stereotactic-biopsy-platforms-with-intraoperative-imaging-guidance
#7
REVIEW
Ahmed Mohyeldin, J Bradley Elder
The resolution and real-time navigation of intraoperative MRI (iMRI) has been leveraged in neurosurgery. We review frameless stereotactic biopsy platforms and focus on emerging technology integrating intraoperative MRI with frameless stereotaxy. Brain biopsy with iMRI allows for an accurate tissue sample with the ability to correct cannula trajectory during surgery, eliminating misdiagnosis secondary to faulty targeting. This technology allows for a percutaneous approach avoiding large incisions, obviates the need for frozen tissue evaluation, has the potential to reduce unnecessary specimen harvesting and operating room time, and optimizes safety of targeting deep brain lesions...
October 2017: Neurosurgery Clinics of North America
https://www.readbyqxmd.com/read/28889128/hemorrhage-detection-and-incidence-during-magnetic-resonance-guided-deep-brain-stimulator-implantations
#8
Alastair J Martin, Philip A Starr, Jill L Ostrem, Paul S Larson
BACKGROUND/AIMS: Intraoperative magnetic resonance imaging (iMRI) is increasingly used to implant deep brain stimulator (DBS) electrodes. The approach has the advantages of a high targeting accuracy, minimization of brain penetrations, and allowance of implantation under general anesthesia. The hemorrhagic complications of iMRI-guided DBS implantation have not been studied in a large series. We report on the incidence and characteristics of hemorrhage during these procedures. METHODS: Hemorrhage incidence was assessed in a series of 231 iMRI procedures (374 electrodes implanted)...
September 9, 2017: Stereotactic and Functional Neurosurgery
https://www.readbyqxmd.com/read/28842228/microelectrode-recording-guided-versus-intraoperative-mri-guided-in-stn-deep-brain-stimulation-surgery-for-parkinson-s-disease-a-one-year-follow-up-study
#9
Xuemeng Liu, Jibo Zhang, Kai Fu, Rui Gong, Jincao Chen, Jie Zhang
Microelectrode recording (MER) and Intraoperative MRI (iMRI) have been used in DBS surgery for Parkinson's disease (PD), but comparative methodology is as yet lacking. Therefore, we compared the one-year follow-up outcomes of MER guided and iMRI guided STN-DBS surgery in PD patients. METHOD: We conducted a review comparing PD patients who underwent MER guided (n=76, group A) and iMRI guided STN-DBS surgery (n=61, group B ) in our institution. Pre- and postoperative assessments included UPDRS-III score, PDQ-39, MMSE, LEDDs and MR images...
August 22, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28830894/endothelial-ship2-suppresses-nox2-nadph-oxidase-dependent-vascular-oxidative-stress-endothelial-dysfunction-and-systemic-insulin-resistance
#10
Nicole T Watt, Matthew C Gage, Peysh A Patel, Hema Viswambharan, Piruthivi Sukumar, Stacey Galloway, Nadira Y Yuldasheva, Helen Imrie, Andrew Mn Walker, Kathryn J Griffin, Natalia Makava, Anna Skromna, Katherine Bridge, David J Beech, Stéphane Schurmans, Stephen B Wheatcroft, Mark T Kearney, Richard M Cubbon
Shc homology 2-containing inositol 5´ phosphatase-2 (SHIP2) is as lipid phosphatase which inhibits insulin signaling downstream of phosphoinositide-3-kinase (PI3K); its role in vascular function is poorly understood. To examine its role in endothelial cell (EC) biology, we generated mice with catalytic inactivation of one SHIP2 allele selectively in EC (ECSHIP2(Δ/+)). Hyperinsulinemic euglycemic clamping studies revealed ECSHIP2(Δ/+) were resistant to insulin-stimulated glucose uptake in adipose tissue and skeletal muscle, compared with littermate controls...
August 22, 2017: Diabetes
https://www.readbyqxmd.com/read/28828722/the-changing-sella-internal-carotid-artery-shift-during-transsphenoidal-pituitary-surgery
#11
Carlo Serra, Nicolai Maldaner, Giovanni Muscas, Victor Staartjes, Athina Pangalu, David Holzmann, Michael Soyka, Christoph Schmid, Luca Regli
PURPOSE: Injuries to the internal carotid artery (ICA) are potentially lethal complications in transsphenoidal surgery (TSS) for pituitary lesions. The intercarotid distance (ICD) is thus a major parameter, determining the width of the surgical corridor in TSS. The purpose of the study is to investigate changes in ICD at different levels of the ICA during and after TSS using high definition intraoperative MRI (3T-iMRI). METHODS: Pre-, intra- and 3 months postoperative MRI images of 85 TSS patients were reviewed...
August 21, 2017: Pituitary
https://www.readbyqxmd.com/read/28780845/-implementation-of-multimodal-navigation-combined-with-intraoperative-magnetic-resonance-imaging-in-the-frameless-stereotactic-biopsy-of-intracranial-lesions
#12
J S Zhang, X L Chen, Q Wang, Y Z Hou, G C Sun, F Y Li, X G Yu, B N Xu
Objective: To investigate the impact and value of multimodal navigation and intraoperative magnetic resonance imaging (iMRI) on the biopsy of intracranial lesions. Methods: From February, 2009 to December, 2016, this study enrolled 156 patients, who underwent multimodal navigation and iMRI-guided brain biopsy in the Neurosurgery Department of PLA General Hospital. Metabolic information was used for biopsy target selection. Intraoperative guidance helped biopsy trajectory avoid the eloquent structures. iMRI was performed to prove the biopsy accuracy and to revise the incorrect biopsy...
August 1, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28770902/role-of-intra-operative-mri-imri-in-improving-extent-of-resection-and-survival-in-patients-with-glioblastoma-multiforme
#13
Inamullah Khan, Muhammad Waqas, Muhammad Shahzad Shamim
Multiple intraoperative aids have been introduced to improve the extent of resection (EOR) in Glioblastoma Multiforme (GBM) patients, avoiding any new neurological deficits. Intraoperative MRI (iMRI) has been debated for its utility and cost for nearly two decades in neurosurgical literature. Review of literature suggests improved EOR in GBM patients who underwent iMRI assisted surgical resections leading to higher overall survival (OS) and progression free survival (PFS). iMRI provides real time intraoperative imaging with reasonable quality...
July 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28761393/a-combined-intravascular-mri-endoscope-and-intravascular-ultrasound-ivus-transducer-for-high-resolution-image-guided-ablation
#14
Xiaoyang Liu, Nicholas Ellens, Emery Williams, Everette Clif Burdette, Parag Karmarkar, Paul Bottomley
An intravascular MRI (IMRI) loopless antenna is combined for the first time with an intravascular water-cooled ultrasound ablation transducer as a possible tool for providing high-resolution MRI-guided ablations of pathological tissue via intravascular access. High resolution anatomical MRI, and real-time MRI thermometry were used to monitor ablation delivery in phantoms and tissue specimens. Results show that IMRI can guide IVUS-mediated directional ablation with minimal image artifacts. This permits the monitoring of thermal dose and therapy titration while minimizing potential thermal damage to the vessel wall...
April 2017: Proceedings of the International Society for Magnetic Resonance in Medicine ... Scientific Meeting and Exhibition
https://www.readbyqxmd.com/read/28737744/delivering-advanced-therapies-the-big-pharma-approach
#15
REVIEW
J Tarnowski, D Krishna, L Jespers, A Ketkar, R Haddock, J Imrie, S Kili
After two decades of focused development and some recent clinical successes, cell and gene therapy (CGT) is emerging as a promising approach to personalized medicines. Genetically engineered cells as a medical modality are poised to stand alongside or in combination with small molecule and biopharmaceutical approaches to bring new therapies to patients globally. Big pharma can have a vital role in industrializing CGT by focusing on diseases with high unmet medical need and compelling genetic evidence. Pharma should invest in manufacturing and supply chain solutions that deliver reproducible, high-quality therapies at a commercially viable cost...
July 24, 2017: Gene Therapy
https://www.readbyqxmd.com/read/28724723/nucleoredoxin-guards-against-oxidative-stress-by-protecting-antioxidant-enzymes
#16
Sophie Kneeshaw, Rumana Keyani, Valérie Delorme-Hinoux, Lisa Imrie, Gary J Loake, Thierry Le Bihan, Jean-Philippe Reichheld, Steven H Spoel
Cellular accumulation of reactive oxygen species (ROS) is associated with a wide range of developmental and stress responses. Although cells have evolved to use ROS as signaling molecules, their chemically reactive nature also poses a threat. Antioxidant systems are required to detoxify ROS and prevent cellular damage, but little is known about how these systems manage to function in hostile, ROS-rich environments. Here we show that during oxidative stress in plant cells, the pathogen-inducible oxidoreductase Nucleoredoxin 1 (NRX1) targets enzymes of major hydrogen peroxide (H2O2)-scavenging pathways, including catalases...
July 19, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28698020/first-outbreak-of-colonization-by-linezolid-and-glycopeptide-resistant-enterococcus-faecium-harbouring-the-cfr-gene-in-a-uk-nephrology-unit
#17
T Inkster, J Coia, D Meunier, M Doumith, K Martin, R Pike, L Imrie, H Kane, M Hay, C Wiuff, J Wilson, C Deighan, K L Hopkins, N Woodford, R Hill
AIM: To describe an outbreak of colonization by linezolid- and glycopeptide-resistant Enterococcus faecium harbouring the cfr gene in a UK nephrology unit. METHODS: Isolates of linezolid-resistant E. faecium were typed by pulsed-field gel electrophoresis (PFGE), and examined by polymerase chain reaction (PCR) and sequencing for the transmissible cfr gene that confers resistance to linezolid. Enhanced environmental cleaning, initial and weekly screening of all patients, and monitoring of adherence to standard infection control precautions were implemented...
July 8, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28645466/the-scottish-enhanced-staphylococcus-aureus-bacteraemia-surveillance-programme-the-first-18-months-of-data-in-children
#18
F Murdoch, J Danial, A K Morris, E Czarniak, J L Bishop, E Glass, L J Imrie
BACKGROUND: National enhanced surveillance of Staphylococcus aureus bacteraemia (SAB) commenced on 1(st) October 2014 to gain a more in-depth understanding of the epidemiology of SAB in Scotland. Children under 16 years of age were analysed separately from adults because previous studies had demonstrated epidemiological differences. AIM: To identify risk factors and patient populations at greatest risk to enable the development of focused improvement plans. METHODS: All National Health Service (NHS) boards within NHS Scotland take part in the mandatory enhanced surveillance, with data collected by trained data collectors using nationally agreed definitions...
June 20, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28637756/high-resolution-metatranscriptomics-reveals-the-ecological-dynamics-of-mosquito-associated-rna-viruses-in-western-australia
#19
Mang Shi, Peter Neville, Jay Nicholson, John-Sebastian Eden, Allison Imrie, Edward C Holmes
Mosquitoes harbor a high diversity of RNA viruses, including many that impact human health. Despite a growing effort to describe the extent and nature of the mosquito virome, little is known about how these viruses persist, spread, and interact with both their hosts and other microbes. To address this issue we performed a metatranscriptomics analysis of 12 Western Australian mosquito populations structured by species and geographic location. Our results identified the complete genomes of 24 species of RNA viruses from a diverse range of viral families and orders, among which 19 are newly described...
September 1, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28624561/safety-utility-and-clinical-results-of-continuous-intraoperative-electrophysiologic-monitoring-in-1-5t-imri-guided-surgery
#20
Martin Breitkopf, Sotirios Bisdas, Marina Liebsch, Felix Behling, Benjamin Bender, Marcos Tatagiba, Constantin Roder
OBJECTIVE: To show that the combined use of intraoperative high-field MRI (iMRI) and electrophysiologic monitoring (IOM) is feasible, safe, and beneficial for patients. METHODS: The setup, surgical, imaging, and clinical results of 110 patients with eloquent intracranial lesions with the combined use of 1.5T iMRI and IOM were analyzed. RESULTS: 187 iMRI scans were performed with IOM needles in place, resulting in a total experience of using >4000 electrodes in the iMRI...
October 2017: World Neurosurgery
keyword
keyword
1500
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"