keyword
MENU ▼
Read by QxMD icon Read
search

cerebral visual impairment

keyword
https://www.readbyqxmd.com/read/29753093/epidemiology-of-septo-optic-dysplasia-with-focus-on-prevalence-and-maternal-age-a-eurocat-study
#1
Ester Garne, Anke Rissmann, Marie-Claude Addor, Ingeborg Barisic, Jorieke Bergman, Paula Braz, Clara Cavero-Carbonell, Elizabeth S Draper, Miriam Gatt, Martin Haeusler, Kari Klungsoyr, Jennifer J Kurinczuk, Nathalie Lelong, Karen Luyt, Catherine Lynch, Mary T O'Mahony, Olatz Mokoroa, Vera Nelen, Amanda J Neville, Anna Pierini, Hanitra Randrianaivo, Judith Rankin, Florence Rouget, Bruno Schaub, David Tucker, Christine Verellen-Dumoulin, Diana Wellesley, Awi Wiesel, Nataliia Zymak-Zakutnia, Monica Lanzoni, Joan K Morris
Septo-optic nerve dysplasia is a rare congenital anomaly with optic nerve hypoplasia, pituitary hormone deficiencies and midline developmental defects of the brain. The clinical findings are visual impairment, hypopituitarism and developmental delays. The aim of this study was to report prevalence, associated anomalies, maternal age and other epidemiological factors from a large European population based network of congenital anomaly registries (EUROCAT). Data from 29 full member registries for the years 2005-2014 were included, covering 6...
May 9, 2018: European Journal of Medical Genetics
https://www.readbyqxmd.com/read/29741274/neurologic-impairments-from-pediatric-low-grade-glioma-by-tumor-location-and-timing-of-diagnosis
#2
Zsila S Sadighi, Elizabeth Curtis, Jennifer Zabrowksi, Catherine Billups, Amar Gajjar, Raja Khan, Ibrahim Qaddoumi
BACKGROUND: The neurologic outcomes of low-grade gliomas (LGGs) according to tumor location and duration of presenting symptoms remain poorly characterized in children. PROCEDURE: We retrospectively reviewed neurologic impairments in 246 pediatric patients with LGGs (88 with optic pathway and midline tumors, 56 with posterior fossa tumors, 52 with cerebral hemisphere tumors, 35 with brainstem tumors, and 15 with spinal cord tumors) who were treated at St. Jude Children's Research Hospital between 1995 and 2005...
May 9, 2018: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29740190/does-duration-of-caffeine-therapy-in-preterm-infants-born-%C3%A2-1250-g-at-birth-influence-neurodevelopmental-nd-outcomes-at-3-years-of-age
#3
A Lodha, Y Rabi, A Soraisham, J Dobry, Arijit Lodha, H Amin, E Al Awad, S Tang, A Sahai, V Bhandari
OBJECTIVE: To evaluate the effect of duration of caffeine use on long-term neurodevelopmental (ND) outcomes at 3 years corrected age (CA) in preterm infants with birthweights (BW) ≤ 1250 g. DESIGN/METHODS: All surviving infants with BW ≤ 1250 g admitted to the Foothills Medical Center neonatal intensive care unit (NICU) from January 2002 to December 2009 who received the first dose of caffeine in the first week of life and were followed up at three years CA were included in the study...
May 8, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29740187/do-preterm-infants-with-a-birth-weight-%C3%A2-1250-g-born-to-single-parent-families-have-poorer-neurodevelopmental-outcomes-at-age-3-than-those-born-to-two-parent-families
#4
Abhay Lodha, Jahan Lakhani, Krystyna Ediger, Selphee Tang, Arijit Lodha, Vardhil Gandhi, Dianne Creighton
OBJECTIVE: Investigate neurodevelopmental outcomes at 3 years corrected age in infants with a birth weight ≤1250 g born to single parents. STUDY DESIGN: Infants born between 1995 and 2010 with a birth weight ≤1250 g were considered eligible. Primary outcome was neurodevelopmental impairment; considered present if a child had any of the following: cerebral palsy, cognitive delay, visual impairment, or deafness/neurosensory hearing impairment. Univariate and multivariate analyses were performed...
May 8, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29739345/atypical-central-retinal-artery-occlusion-as-the-first-presentation-of-poems-syndrome-a-case-report
#5
Panitha Jindahra, Charungthai Dejthevaporn, Pimjai Niparuck, Jariya Waisayarat, Piyaphon Cheecharoen, Thanatporn Threetong, Purit Petpiroon, Tharikarn Sujirakul, Anuchit Poonyathalang, Kavin Vanikieti
BACKGROUND: POEMS syndrome is a plasma cell disorder, which clinically manifests from paraneoplastic syndrome: polyneuropathy, organomegaly, endocrinopathy, monoclonal plasma cell disorder, and skin changes. The most common ocular manifestation is optic disc swelling, whereas other ocular manifestations; cystoid macular edema, serous macular detachment, venous sinus thrombosis, infiltrative orbitopathy, uveitis, neovascularization of the disc, peripapillary choroidal neovascularization and optic disc drusen, had also been reported...
May 8, 2018: BMC Neurology
https://www.readbyqxmd.com/read/29734176/mitofusin-2-exerts-a-protective-role-in-ischemia-reperfusion-injury-through-increasing-autophagy
#6
Cheng Peng, Wei Rao, Lei Zhang, Fan Gao, Hao Hui, Kai Wang, Shuhui Dai, Yuefan Yang, Peng Luo, Yihui Ma, Wenke Ma, Xinguang Yu, Zhou Fei
BACKGROUND/AIMS: Autophagy is essential for maintaining cellular homeostasis and the survival of terminally differentiated cells as neurons. In this study, we aim to investigate whether mitofusin 2, a mitochondrial fusion protein, mediates autophagy in cerebral ischemia/reperfusion (I/R) injury. METHODS: Primary cultured neurons were treated with oxygen-glucose deprivation/reperfusion to mimic cerebral I/R injury in vitro. Autophagosomes were visualized upon TEM...
May 3, 2018: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29729166/treatment-for-patients-with-neglekt-after-ischemic-stroke
#7
Oleksander R Pulyk, Myroslava V Hyryavets
OBJECTIVE: Introduction: Motion disturbances are one of the main causes of disabling patients after a stroke, causing problems of walking and balance. Only 20% of patients after a stroke are returned to work, and only 10% of patients can return a daily activity level that was before the disease. Cognitive impairment occurs in 30-50% of patients who have suffered a cerebral stroke. One of the most important and ultimately unresolved problems in rehabilitation of patients is the rehabilitation of patients with a syndrome of ignorance (neglekt)...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29725862/ergs-on-the-brain-the-benefits-of-simultaneous-flash-retinal-and-cortical-responses-in-paediatric-cerebral-visual-impairment
#8
Sian E Handley, Dorothy A Thompson, Katrina L Prise, Alki Liasis
PURPOSE: To highlight the importance of simultaneous flash electroretinogram (ERG) and visual evoked potential (VEP) recording to differentiate a true flash VEP response from an artefact caused by the intrusion of the ERG on a mid-frontal reference electrode in cases of severe cerebral visual impairment (CVI). METHODS: We report an observational case series of four children with severe CVI who underwent simultaneous flash ERG and VEP recordings. Flash VEPs from Oz-Fz and lower lid skin ERGs referred to Fz were recorded simultaneously to Grass intensity setting 4 flash stimulation...
May 3, 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29718010/phenotypic-variability-in-a-mexican-mestizo-family-with-retinal-vasculopathy-with-cerebral-leukodystrophy-and-trex1-mutation-p-v235gfs-6
#9
Nancy Monroy-Jaramillo, Aurelio Cerón, Elizabeth León, Verónica Rivas, Adriana Ochoa-Morales, María Georgina Arteaga-Alcaraz, Fausto Carlos Nocedal-Rustrian, Cecilia Gallegos, María Elisa Alonso-Vilatela, Teresa Corona, José Flores
Background: Retinal vasculopathy with cerebral leukodystrophy (RVCL) is an adult-onset, autosomal dominant disease involving microvessels of the brain and eye resulting in central nervous system degeneration with visual disturbances, stroke, motor impairment, and cognitive decline. Frameshift mutations at the C-terminus of TREX1 gene are the molecular cause of this disorder. Objectives: The objective of this study is to present the different clinical manifestations of RVCL in three-related patients and to investigate the presence of TREX1 mutation in the extended genealogy...
2018: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/29713311/cryptorchidism-in-boys-with-cerebral-palsy-is-associated-with-the-severity-of-disease-and-with-co-occurrence-of-other-congenital-anomalies
#10
Julia Spencer Barthold, Anton Wintner, Jennifer A Hagerty, Kenneth J Rogers, Md Jobayer Hossain
Background: Cryptorchidism is reported in 40-50% of small case series of cerebral palsy (CP) and attributed to hypothalamic-pituitary-gonadal axis abnormalities, intellectual disability (ID), or cremaster spasticity. We collected demographic and clinical data to define the frequency of cryptorchidism and clinical comorbidities in a large CP population. Methods: Electronic health record data were collected for all male patients ≥7 years of age seen in a large, multidisciplinary CP clinic between 2000 and 2016...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29710708/cerebral-white-matter-lesions-have-low-impact-on-cognitive-function-in-a-large-elderly-memory-clinic-population
#11
Jules J Claus, Mirthe Coenen, Salka S Staekenborg, Jacqueline Schuur, Caroline E M Tielkes, Pieter Koster, Philip Scheltens
BACKGROUND: Evidence suggests that cerebral white matter lesions (WML) play a role in cognitive decline. OBJECTIVE: To assess the impact of cerebral WML on cognitive function relative to absence or presence of medial temporal atrophy (MTA) in a large single-center memory clinic population. METHODS: Patients included had subjective cognitive impairment (SCI, n = 333), mild cognitive impairment (MCI, n = 492) and Alzheimer's disease (AD, n = 832)...
April 27, 2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29706928/repetitive-neonatal-erythropoietin-and-melatonin-combinatorial-treatment-provides-sustained-repair-of-functional-deficits-in-a-rat-model-of-cerebral-palsy
#12
Lauren L Jantzie, Akosua Y Oppong, Fatu S Conteh, Tracylyn R Yellowhair, Joshua Kim, Gabrielle Fink, Adam R Wolin, Frances J Northington, Shenandoah Robinson
Cerebral palsy (CP) is the leading cause of motor impairment for children worldwide and results from perinatal brain injury (PBI). To test novel therapeutics to mitigate deficits from PBI, we developed a rat model of extreme preterm birth (<28 weeks of gestation) that mimics dual intrauterine injury from placental underperfusion and chorioamnionitis. We hypothesized that a sustained postnatal treatment regimen that combines the endogenous neuroreparative agents erythropoietin (EPO) and melatonin (MLT) would mitigate molecular, sensorimotor, and cognitive abnormalities in adults rats following prenatal injury...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29681800/early-retinal-defects-in-fmr1-y-mice-toward-a-critical-role-of-visual-dys-sensitivity-in-the-fragile-x-syndrome-phenotype
#13
Olivier Perche, Chloé Felgerolle, Maryvonne Ardourel, Audrey Bazinet, Arnaud Pâris, Rafaëlle Rossignol, Géraldine Meyer-Dilhet, Anne-Laure Mausset-Bonnefont, Betty Hébert, David Laurenceau, Céline Montécot-Dubourg, Arnaud Menuet, Jean-Charles Bizot, Jacques Pichon, Isabelle Ranchon-Cole, Sylvain Briault
Fragile X Syndrome (FXS) is caused by a deficiency in Fragile X Mental Retardation Protein (FMRP) leading to global sensorial abnormalities, among which visual defects represent a critical part. These visual defects are associated with cerebral neuron immaturity especially in the primary visual cortex. However, we recently demonstrated that retinas of adult Fmr1 -/y mice, the FXS murine model, present molecular, cellular and functional alterations. However, no data are currently available on the evolution pattern of such defects...
2018: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/29679197/neuropsychological-impacts-of-indirect-revascularization-for-pediatric-moyamoya-disease
#14
WooHyun Kim, Eun-Young Lee, Seong-Eun Park, Eun-Kyung Park, Ju-Seong Kim, Dong-Seok Kim, Kyu-Won Shim
PURPOSE: Moyamoya disease (MMD) commonly leads to neurocognitive impairment. This study was carried out to show that temporal encephaloduroarteriosynangiosis (EDAS) has a positive neuropsychological impact on pediatric MMD patients. METHODS: Fifty-five participants diagnosed with MMD from 2008 to 2014 were included in this retrospective study. The mean age at the preoperative evaluation was 9.5 years and the mean age at postoperative evaluation was 10.4. The average interval of initial and follow-up test was 10 months...
April 20, 2018: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29679045/trends-in-the-neurodevelopmental-outcomes-among-preterm-infants-from-2003-2012-a-retrospective-cohort-study-in-japan
#15
Hidehiko Nakanishi, Hideyo Suenaga, Atsushi Uchiyama, Yumi Kono, Satoshi Kusuda
OBJECTIVES: To determine the trends in mortality and the prevalence of abnormal neurodevelopmental outcomes among preterm Japanese infants. STUDY DESIGN: A retrospective multicenter cohort of 30,793 preterm infants born at a gestational age ≤32 weeks, between 2003 and 2012, in the Neonatal Research Network, Japan, was evaluated in the primary analysis. Finally, 13,661 infants were followed-up until 3 years of age and evaluated for neurodevelopmental outcomes, including cerebral palsy (CP), home oxygen therapy (HOT) use, and visual, hearing, and cognitive impairments...
April 20, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29675944/advanced-mr-diffusion-imaging-and-chemotherapy-related-changes-in-cerebral-white-matter-microstructure-of-survivors-of-childhood-bone-and-soft-tissue-sarcoma
#16
Charlotte Sleurs, Jurgen Lemiere, Daan Christiaens, Thibo Billiet, Ronald Peeters, Stefan Sunaert, Anne Uyttebroeck, Sabine Deprez
With the increase of survival rates of pediatric cancer patients, the number of children facing potential cognitive sequelae has grown. Previous adult studies suggest that white matter (WM) microstructural changes may contribute to cognitive impairment. This study aims to investigate WM microstructure in childhood bone and soft tissue sarcoma. Differences in (micro-)structure can be investigated using diffusion MRI (dMRI). The typically used diffusion tensor model (DTI) assumes Gaussian diffusion, and lacks information about fiber populations...
April 20, 2018: Human Brain Mapping
https://www.readbyqxmd.com/read/29674416/altered-white-matter-microstructure-in-the-corpus-callosum-and-its-cerebral-interhemispheric-tracts-in-adolescent-idiopathic-scoliosis-diffusion-tensor-imaging-analysis
#17
C Xue, L Shi, S C N Hui, D Wang, T P Lam, C-B Ip, B K W Ng, J C Y Cheng, W C W Chu
BACKGROUND AND PURPOSE: Neural system was one of the important contributors to the etiopathogenesis of adolescent idiopathic scoliosis; additionally, the morphology of corpus callosum interconnecting both hemispheres of the brain was found to be altered morphologically. Our aim was to evaluate and compare the microstructural changes of the corpus callosum and its interhemispheric white matter fiber tracts interconnecting both cerebral hemispheres in patients with adolescent idiopathic scoliosis and matched controls using diffusion tensor imaging...
April 19, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29616521/the-relationship-between-cerebral-oxygen-saturation-and-quantitative-metrics-of-neurological-function-after-coronary-bypass-surgery-a-feasibility-study
#18
Joanna S Semrau, Stephen H Scott, Andrew G Hamilton, Dimitri Petsikas, Darrin M Payne, Gianluigi Bisleri, Tarit Saha, J Gordon Boyd
BACKGROUND: It is well-known that patients undergoing coronary artery bypass grafting (CABG) surgery may experience neurological dysfunction following their operation. However, the nature of this dysfunction has not been properly quantified. Furthermore, the relationship between post-operative impairment and cerebral oxygen saturation during surgery has remained unclear. This study aims to define the feasibility of using robotic technology to quantify post- CABG neurocognitive function, and to correlate these objective metrics with intraoperative brain tissue oxygen...
April 3, 2018: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29615062/kars-related-diseases-progressive-leukoencephalopathy-with-brainstem-and-spinal-cord-calcifications-as-new-phenotype-and-a-review-of-literature
#19
Anna Ardissone, Davide Tonduti, Andrea Legati, Eleonora Lamantea, Rita Barone, Imen Dorboz, Odile Boespflug-Tanguy, Gabriella Nebbia, Marco Maggioni, Barbara Garavaglia, Isabella Moroni, Laura Farina, Anna Pichiecchio, Simona Orcesi, Luisa Chiapparini, Daniele Ghezzi
BACKGROUND: KARS encodes lysyl- transfer ribonucleic acid (tRNA) synthetase, which catalyzes the aminoacylation of tRNA-Lys in the cytoplasm and mitochondria. Eleven families/sporadic patients and 16 different mutations in KARS have been reported to date. The associated clinical phenotype is heterogeneous ranging from early onset encephalopathy to isolated peripheral neuropathy or nonsyndromic hearing impairment. Recently additional presentations including leukoencephalopathy as predominant cerebral involvement or cardiomyopathy, isolated or associated with muscular and cerebral involvement, have been reported...
April 4, 2018: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/29611075/presurgical-localization-and-spatial-shift-of-resting-state-networks-in-patients-with-brain-metastases
#20
Ju-Rong Ding, Fangmei Zhu, Bo Hua, Xingzhong Xiong, Yuqiao Wen, Zhongxiang Ding, Paul M Thompson
Brain metastases are the most prevalent cerebral tumors. Resting state networks (RSNs) are involved in multiple perceptual and cognitive functions. Therefore, precisely localizing multiple RSNs may be extremely valuable before surgical resection of metastases, to minimize neurocognitive impairments. Here we aimed to investigate the reliability of independent component analysis (ICA) for localizing multiple RSNs from resting-state functional MRI (rs-fMRI) data in individual patients, and further evaluate lesion-related spatial shifts of the RSNs...
April 2, 2018: Brain Imaging and Behavior
keyword
keyword
14992
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"