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Endocrine guidelines

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https://www.readbyqxmd.com/read/29447711/no-355-physiologic-basis-of-pain-in-labour-and-delivery-an-evidence-based-approach-to-its-management
#1
Julie Bonapace, Guy-Paul Gagné, Nils Chaillet, Raymonde Gagnon, Emmanuelle Hébert, Sarah Buckley
OBJECTIVE: To review the evidence relating to nonpharmacological approaches in the management of pain during labour and delivery. To formulate recommendations for the usage of nonpharmacological approaches to pain management. OPTIONS: Nonpharmacological methods available for pain management during labour and delivery exist. These should be included in the counselling and care of women. EVIDENCE: PubMed and Medline were searched for articles in French and English on subjects related to "breastfeeding," "pain," "epidural," "anaesthesia," "analgesia," "labour," "labor," and combined with "gate control theory," "alternative therapies," "massage," "position," "mobility," "TENS," "bathing," "DNIC," "acupuncture," "acupressure," "sterile water injection," "higher center," "control mind," "cognitive structuring," "holistic health," "complementary therapy(ies)," "breathing," "relaxation," "mental imagery," "visualization," "mind focusing," "hypnosis," "auto-hypnosis," "sophrology," "mind and body interventions," "music," "odors," "biofeedback," "Lamaze," "Bonapace," "prenatal training," "gymnastic," "chanting," "haptonomy," "environment," "transcutaneous electrical stimulus-stimulation," "antenatal education," "support," "continuous support," "psychosocial support," "psychosomatic medicine," "supportive care," "companion," "intrapartum care," "nurse," "midwife(ves)," "father," "doula," "caregiver," " hormones," "oxytocin," "endorphin," "prolactin," "catecholamine," "adrenaline," and "noradrenaline" from 1990 to December 2015...
February 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29446832/an-assessment-of-18-f-fdg-pet-ct-for-thoracic-screening-and-risk-stratification-of-pulmonary-nodules-in-multiple-endocrine-neoplasia-type-1
#2
Alvin So, Owen Pointon, Richard Hodgson, John Burgess
CONTEXT: Bronchopulmonary neuroendocrine tumours (bpNETs) and thymic carcinoid (ThC) are features of Multiple Endocrine Neoplasia Type 1 (MEN 1) and surveillance guidelines recommend periodic thoracic imaging. The optimal thoracic imaging modality and screening frequency remains uncertain as does the prognosis of small lung nodules when identified. OBJECTIVES: To evaluate fluorodeoxyglucose positron emission tomography/computed tomography ( 18 F-FDG PET/CT) for identification and prognostic assessment of thoracic lesions in MEN 1...
February 15, 2018: Clinical Endocrinology
https://www.readbyqxmd.com/read/29445865/risk-of-recurrence-in-a-homogeneously-managed-pt3-differentiated-thyroid-carcinoma-population
#3
Nathalie Chereau, Etienne Dauzier, Gaëlle Godiris-Petit, Séverine Noullet, Isabelle Brocheriou, Laurence Leenhardt, Camille Buffet, Fabrice Menegaux
BACKGROUND: International guidelines for the management of differentiated thyroid cancers are based on the 7th TNM classification: pT3 tumors are defined as differentiated thyroid cancers (DTCs) measuring more than 4 cm in their greatest dimension that are limited to the thyroid or any tumor with minimal extrathyroidal extension (ETE; sternothyroid muscle or perithyroid soft tissues). Differences in clinicohistological features and prognosis among patients with pT3 tumors remain controversial, and studies regarding pT3 subgroups are lacking...
February 14, 2018: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/29442352/guidelines-of-polish-national-societies-diagnostics-and-treatment-of-thyroid-carcinoma-2018-update
#4
Barbara Jarząb, Marek Dedecjus, Dorota Słowińska-Klencka, Andrzej Lewiński, Zbigniew Adamczewski, Ryszard Anielski, Maciej Bagłaj, Agata Bałdys-Waligórska, Marcin Barczyński, Tomasz Bednarczuk, Artur Bossowski, Monika Buziak-Bereza, Ewa Chmielik, Andrzej Cichocki, Agnieszka Czarniecka, Rafał Czepczyński, Janusz Dzięcioł, Tomasz Gawlik, Daria Handkiewicz-Junak, Kornelia Hasse-Lazar, Alicja Hubalewska-Dydejczyk, Krystian Jażdżewski, Beata Jurecka-Lubieniecka, Michał Kalemba, Grzegorz Kamiński, Małgorzata Karbownik-Lewińska, Mariusz Klencki, Beata Kos-Kudła, Agnieszka Kotecka-Blicharz, Aldona Kowalska, Jolanta Krajewska, Aleksandra Kropińska, Aleksandra Kukulska, Emilia Kulik, Andrzej Kułakowski, Krzysztof Kuzdak, Dariusz Lange, Aleksandra Ledwon, Elżbieta Lewandowska-Jabłońska, Katarzyna Łącka, Barbara Michalik, Anna Nasierowska-Guttmejer, Janusz Nauman, Marek Niedziela, Ewa Małecka-Tendera, Małgorzata Oczko-Wojciechowska, Tomasz Olczyk, Ewa Paliczka-Cieślik, Lech Pomorski, Zbigniew Puch, Józef Roskosz, Marek Ruchała, Dagmara Rusinek, Stanisław Sporny, Agata Stanek-Widera, Zoran Stojcev, Aleksandra Syguła, Anhelli Syrenicz, Sylwia Szpak-Ulczok, Tomasz Tomkalski, Zbigniew Wygoda, Jan Włoch, Ewa Zembala-Nożyńska
Significant advances have been made in thyroid can-cer research in recent years, therefore relevant clinical guidelines need to be updated. The current Polish guidelines "Diagnostics and Treatment of Thyroid Carcinoma" have been formulated at the "Thyroid Cancer and Other Malignancies of Endocrine Glands" conference held in Wisła in November 2015 [1].
2018: Endokrynologia Polska
https://www.readbyqxmd.com/read/29433884/squamous-differentiation-in-papillary-thyroid-carcinoma-a-rare-feature-of-aggressive-disease
#5
Toni Beninato, Wouter P Kluijfhout, Frederick Thurston Drake, Elham Khanafshar, Jessica E Gosnell, Wen T Shen, Quan-Yang Duh, Insoo Suh
BACKGROUND: Papillary thyroid carcinoma with squamous differentiation (PTC-SD) is a poorly understood pathologic finding of unknown clinical significance. Selected case reports have suggested that PTC-SD is an aggressive tumor with a poor prognosis. Here we present the largest case series of PTC-SD reported in the United States. MATERIALS AND METHODS: The cancer registry at our tertiary care referral center was reviewed to identify all patients from 1995-2015 who had been diagnosed with PTC-SD on initial total thyroidectomy or lymph node dissection for recurrent disease...
March 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29420349/thyroid-disorders-in-athletes
#6
John R Luksch, Philip B Collins
When athletic performance begins to deteriorate, it is important to identify possible underlying etiologies to explain such a phenomenon. Causes include inadequate nutrition, improper training habits, infection, and hematologic or endocrine diseases. In athletes, a thorough investigation of potentially reversible underlying medical conditions may be warranted when there are noted disruptions in training, competition, and recovery. Thyroid disorders should be considered in athletes in whom such a condition is suspected...
February 2018: Current Sports Medicine Reports
https://www.readbyqxmd.com/read/29395184/management-of-hypertension-and-high-low-density-lipoprotein-in-pediatric-type-1-diabetes
#7
Michelle L Katz, Zijing Guo, Lori M Laffel
OBJECTIVE: To evaluate hypertension and hyperlipidemia management patterns in youth with type 1 diabetes and to assess perceived effectiveness of management strategies and barriers to management. STUDY DESIGN: An electronic survey, including clinical scenarios, fielded to pediatric providers (members of the American Diabetes Association Diabetes in Youth Interest Group, Pediatric Endocrine Society, or T1D Exchange). RESULTS: Respondents (N = 207, 86% MDs, 68% female) were practicing clinicians for youth with type 1 diabetes...
January 30, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29388931/-the-therapeutic-and-recreational-potential-of-the-%C3%A2-goryachy-plyazh%C3%A2-physiotherapeutic-facility-on-the-kunashir-island
#8
L V Veremchuk, B I Chelnokova, L S Barskova, T A Gvozdenko, I V Kukayev, N L Savochkina
The ever increasing attention to the further development of the health resort business and touristic activities in this country implies the necessity of the proper scientifically sound substantiation for the more efficient exploitation of the available spa and health resort resources of the Russian Far East as well as the ample recreational potential of this region taking into consideration that they have not been completely utilized during the preceding period. AIM: The objective of the present study was to evaluate the of the «Goryachy Plyazh (Hot Beach)» physiotherapeutic facility on the Kunashir island...
December 28, 2017: Voprosy Kurortologii, Fizioterapii, i Lechebnoĭ Fizicheskoĭ Kultury
https://www.readbyqxmd.com/read/29378479/preimplantation-genetic-diagnosis-of-multiple-endocrine-neoplasia-type-2a-using-informative-markers-identified-by-targeted-sequencing
#9
Songchang Chen, Shuyuan Li, Junyu Zhang, Lanlan Zhang, Yiyao Chen, Li Wang, Li Jin, Yuting Hu, Xiao-Ping Qi, Hefeng Huang, Chenming Xu
BACKGROUND: The revised guidelines for the management of medullary thyroid carcinoma recommend that genetic counseling regarding reproductive options, including preimplantation genetic diagnosis (PGD), be considered for all RET mutation carriers of reproductive age to avoid the transmission of multiple endocrine neoplasia type 2 (MEN2). However, the high complexity and cost of PGD have hindered its widespread use. Thus, it is necessary to establish a simple and relatively inexpensive method to facilitate the PGD of MEN2...
January 29, 2018: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/29369732/pam50-risk-of-recurrence-score-predicts-10-year-distant-recurrence-in-a-comprehensive-danish-cohort-of-postmenopausal-women-allocated-to-5-years-of-endocrine-therapy-for-hormone-receptor-positive-early-breast-cancer
#10
Anne-Vibeke Lænkholm, Maj-Britt Jensen, Jens Ole Eriksen, Birgitte Bruun Rasmussen, Ann S Knoop, Wesley Buckingham, Sean Ferree, Carl Schaper, Torsten O Nielsen, Taryn Haffner, Torben Kibøl, Maj-Lis Møller Talman, Anne Marie Bak Jylling, Tomasz Piotr Tabor, Bent Ejlertsen
Purpose The PAM50-based Prosigna risk of recurrence (ROR) score has been validated in randomized clinical trials to predict 10-year distant recurrence (DR). The value of Prosigna for predicting DR was examined in a comprehensive nationwide Danish cohort consisting of postmenopausal women with hormone receptor-positive early breast cancer treated with 5 years of endocrine therapy alone. Patients and Methods Using the population-based Danish Breast Cancer Cooperative Group database, follow-up data were collected on all patients diagnosed from 2000 through 2003 who, by nationwide guidelines, were treated with endocrine therapy for 5 years...
January 25, 2018: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29363225/uptake-of-adjuvant-breast-cancer-treatments-recommended-by-multi-disciplinary-meetings
#11
Melinda Pattanasri, Kenneth Elder, Carolyn Nickson, Samuel Cooke, Dorothy Machalek, Allison Rose, Arlene Mou, John P Collins, Allan Park, Richard De Boer, Claire Phillips, Vicki Pridmore, Helen Farrugia, G Bruce Mann
BACKGROUND: Adjuvant therapy for breast cancer is routinely discussed and recommended in multi-disciplinary meetings (MDMs). Current literature explores how treatments received by patients differ from national guidelines; however, it does not explore whether treatment is concordant with MDMs. This study provides an Australian perspective on the uptake of MDM recommendations and reasons for non-concordance. METHODS: A retrospective cohort study of patients with breast cancer presented at The Royal Melbourne Hospital MDM in 2010 and 2014 to investigate the concordance between MDM recommendations and treatment received...
January 23, 2018: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29353717/medical-neglect-at-a-tertiary-paediatric-hospital
#12
Julia Parmeter, Dimitra Tzioumi, Susan Woolfenden
Medical neglect is under-researched and the extent of the problem in Australia is unknown. We conducted a review of the referrals for medical neglect to the Child Protection Unit (CPU) at a tertiary children's hospital in Sydney over a 5 years period, from 2011 to 2016, to determine what medical conditions are being referred, the reason for the medical neglect concern and whether cases are managed in line with American Academy of Pediatrics (AAP) guideline on medical neglect. 61 cases of medical neglect were identified, constituting 4...
January 16, 2018: Child Abuse & Neglect
https://www.readbyqxmd.com/read/29352368/endocrine-therapy-and-related-issues-in-hormone-receptor-positive-early-breast-cancer-a-roundtable-discussion-by-the-breast-cancer-therapy-expert-group-bcteg
#13
REVIEW
Jame Abraham, Humberto Caldera, Robert Coleman, Anthony Elias, Matthew P Goetz, Muaiad Kittaneh, Elyse Lower, Reshma Mahtani, E Terry Mamounas, Mark Pegram, Hope Rugo, Lee Schwartzberg, Tiffany Traina, Chuck Vogel
PURPOSE: Management of breast cancer is a rapidly evolving field, and, although evidence-based guidelines are available for clinicians to provide direction on critical issues in patient care, clinicians often left to address these issues in the context of community practice situations with their patients. These include the patient's comorbid conditions, actual versus perceived benefit of treatments, patient's compliance as well as financial/reimbursement issues, and long-term tolerability of therapy...
January 19, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29352052/estrogen-receptor-positive-breast-cancer-exploiting-signaling-pathways-implicated-in-endocrine-resistance
#14
REVIEW
Adam M Brufsky, Maura N Dickler
Advancements in molecular profiling and endocrine therapy (ET) have led to more focused clinical attention on precision medicine. These advances have expanded our understanding of breast cancer (BC) pathogenesis and hold promising implications for the future of therapy. The estrogen receptor-α is a predominant endocrine regulatory protein in the breast and in estrogen-induced BC. Successful targeting of proteins and genes within estrogen receptor (ER) nuclear and nonnuclear pathways remains a clinical goal...
January 19, 2018: Oncologist
https://www.readbyqxmd.com/read/29351143/nutrition-in-the-icu-new-trends-versus-old-fashioned-standard-enteral-feeding
#15
Kristine W A C Koekkoek, Arthur R H van Zanten
PURPOSE OF REVIEW: The narrative review aims to summarize the relevant studies from the last 2 years and provide contextual information to understand findings. RECENT FINDINGS: Recent ICU studies have provided insight in the pathophysiology and time course of catabolism, anabolic resistance, and metabolic and endocrine derangements interacting with the provision of calories and proteins.Early provision of high protein intake and caloric overfeeding may confer harm...
January 18, 2018: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/29350428/meta-analysis-of-fish-early-life-stage-tests-association-of-toxic-ratios-and-acute-to-chronic-ratios-with-modes-of-action
#16
REVIEW
Stefan Scholz, Rene Schreiber, James Armitage, Philipp Mayer, Beate I Escher, Annegret Lidzba, Marc Léonard, Rolf Altenburger
Fish early life stage (FELS) tests (OECD test guideline 210) are widely conducted to estimate chronic fish toxicity. In these tests, fish are exposed from the embryonic to the juvenile life stage. In order to analyse whether certain modes of action are related to high toxic ratios (TR, i.e., ratios between experimental effect and baseline toxicity) and/or acute-to-chronic ratios (ACR) in the FELS test effect concentrations for 183 compounds were extracted from the US EPA ecotoxicity database. Analysis of effect concentration of narcotic compounds indicated that baseline toxicity could be observed in the FELS test at similar concentrations as in acute fish toxicity test...
January 19, 2018: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/29335324/prevalence-of-primary-aldosteronism-in-primary-care-a-cross-sectional-study
#17
Sabine C Käyser, Jaap Deinum, Wim Jc de Grauw, Bianca Wm Schalk, Hans Jhj Bor, Jacques Wm Lenders, Tjard R Schermer, Marion Cj Biermans
BACKGROUND: Primary aldosteronism (PA) is the most frequent cause of secondary hypertension. Reported prevalences of PA vary considerably because of a large heterogeneity in study methodology. AIM: To examine the proportion of patients with PA among patients with newly diagnosed, never treated hypertension. DESIGN AND SETTING: A cross-sectional study set in primary care. METHOD: GPs measured aldosterone and renin in adult patients with newly diagnosed, never treated hypertension...
February 2018: British Journal of General Practice: the Journal of the Royal College of General Practitioners
https://www.readbyqxmd.com/read/29329006/ongoing-unmet-needs-in-treating-estrogen-receptor-positive-her2-negative-metastatic-breast-cancer
#18
REVIEW
Gül A Başaran, Chris Twelves, Véronique Diéras, Javier Cortés, Ahmad Awada
Estrogen receptor-positive (ER+)/human epidermal growth factor receptor 2 negative (HER2-) advanced or metastatic breast cancer (MBC) is the most common MBC subtype and currently remains incurable, with a median overall survival of 24.8 months (95% confidence interval, 21.3-30.3). Common sites of metastases are bone, viscera, and brain, causing significant symptoms that negatively affect patient functioning, quality of life (QoL), and work productivity. Guidelines state that endocrine therapy (ET) is preferable to chemotherapy as first-line treatment for patients with ER+ MBC, regardless of limited visceral metastases, unless rapid tumor response is required or ET resistance is suspected...
February 2018: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/29322022/less-than-total-thyroidectomy-for-goiter-when-and-how
#19
REVIEW
Özer Makay
Benign goiter is the most common endocrine disease that requires surgery, especially in endemic areas suffering from iodine-deficiency. Recent European and American guidelines recommended total thyroidectomy for the surgical treatment of multinodular goiter. Total thyroidectomy has now become the technique of choice and is widely considered the most reliable approach in preventing recurrence. Nevertheless, total thyroidectomy carries a substantial risk in terms of hypoparathyroidism and the morbidity associated with injury to the inferior laryngeal nerve...
December 2017: Gland Surgery
https://www.readbyqxmd.com/read/29320643/2017-american-association-of-clinical-endocrinologists-endocrine-society-update-on-transgender-medicine-case-discussions
#20
Vin Tangpricha, Sabine E Hannema, Michael S Irwig, Walter J Meyer, Joshua D Safer, Wylie C Hembree
OBJECTIVE: Increased numbers of transgender and gender-nonconforming people are presenting to physicians in the United States and abroad due to increased public recognition and acceptance and increased access to healthcare facilities. However, there are still gaps in medical knowledge among endocrinologists and other health care professionals. The purpose of these cases is to present several common clinical vignettes of transgender people presenting in an office setting that illustrate some of the key recommendations of the Endocrine Society's revised Endocrine Treatment of Gender Dysphoria/Gender Incongruent Persons guidelines, cosponsored by the American Association of Clinical Endocrinologists...
December 2017: Endocrine Practice
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