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https://www.readbyqxmd.com/read/29033887/atypical-cerebral-manifestations-of-disseminated-mycobacterium-tuberculosis
#1
Ji Hye Hwang, Kyung Mi Lee, Ji Eun Park, Hyug-Gi Kim, Eui Jong Kim, Woo Suk Choi, Na Rae Yang
BACKGROUND: We investigated the patterns of cerebral manifestations in patients with underlying pulmonary or extrapulmonary tuberculosis or disseminated tuberculosis. MATERIALS AND METHODS: From January 2010 to September 2016, brain magnetic resonance imaging (MRI) scans were obtained to evaluate cerebral manifestations in patients with underlying pulmonary or extrapulmonary tuberculosis. We also included patients with drug-resistant tuberculosis or disseminated tuberculosis...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29027863/potential-utility-of-flair-in-mri-negative-cushing-s-disease
#2
Grégoire P Chatain, Nicholas Patronas, James G Smirniotopoulos, Martin Piazza, Sarah Benzo, Abhik Ray-Chaudhury, Susmeeta Sharma, Maya Lodish, Lynnette Nieman, Constantine A Stratakis, Prashant Chittiboina
OBJECTIVE Accurate presurgical localization of microadenomas in Cushing's disease (CD) leads to improved remission rates and decreased adverse events. Volumetric gradient recalled echo (3D-GRE) MRI detects pituitary microadenomas in CD in up to 50%-80% cases as a focus of hypointensity due to delayed contrast wash-in. The authors have previously reported that postcontrast FLAIR imaging may be useful in detecting otherwise MRI-negative pituitary microadenomas as foci of hyperintensity. This reflects theoretically complementary imaging of microadenomas due to delayed contrast washout...
October 13, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28987701/comparison-of-perioperative-automated-versus-manual-two-dimensional-tumor-analysis-in-glioblastoma-patients
#3
Frauke Kellner-Weldon, Christoph Stippich, Roland Wiest, Vera Lehmann, Raphael Meier, Jürgen Beck, Philippe Schucht, Andreas Raabe, Mauricio Reyes, Andrea Bink
OBJECTIVES: Current recommendations for the measurement of tumor size in glioblastoma continue to employ manually measured 2D product diameters of enhancing tumor. To overcome the rater dependent variability, this study aimed to evaluate the potential of automated 2D tumor analysis (ATA) compared to highly experienced rater teams in the workup of pre- and postoperative image interpretation in a routine clinical setting. MATERIALS AND METHODS: From 92 patients with newly diagnosed GB and performed surgery, manual rating of the sum product diameter (SPD) of enhancing tumor on magnetic resonance imaging (MRI) contrast enhanced T1w was compared to automated machine learning-based tumor analysis using FLAIR, T1w, T2w and contrast enhanced T1w...
October 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28974389/high-prevalence-of-small-vessel-disease-long-after-cranial-irradiation
#4
Masatomo Miura, Makoto Nakajima, Akiko Fujimoto, Yasuyuki Kaku, Takayuki Kawano, Masaki Watanabe, Jun-Ichi Kuratsu, Yukio Ando
Accelerated atherosclerosis of intra- or extracranial large arteries is a major cause of radiation-induced strokes. Recent development of MRI techniques has enabled detection of another important vasculopathy: microinfarcts or microbleeds after cranial irradiation. The purpose of this study was to investigate the incidence and characteristics of small vessel disease after cranial irradiation. MR images and clinical records of 102 outpatients who had undergone cranial irradiation to brain tumors were retrospectively reviewed...
September 30, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28974152/encephalitis-with-antibodies-against-the-gabab-receptor-seizures-as-the-most-common-presentation-at-admission
#5
Xueping Chen, Fan Liu, Jin-Mei Li, Xiao-Qi Xie, Qiong Wang, Dong Zhou, Huifang Shang
OBJECTIVE: Autoimmune encephalitis associated with antibodies against gamma-aminobutyric-acid B receptor (GABABR) has not been described in detail in Chinese patients. METHODS: Patients with anti-GABABR encephalitis treated between January 2013 and December 2015 were analyzed in terms of clinical characteristics, laboratory findings, tumor presence, autoantibody patterns, treatment response and outcomes. RESULTS: Eleven patients were identified (male, N = 8; female, N = 3), with the median age of 51 years...
November 2017: Neurological Research
https://www.readbyqxmd.com/read/28972006/meta-analysis-of-death-and-myocardial-infarction-in-the-define-flair-and-ifr-swedeheart-trials
#6
Colin Berry, John D McClure, Keith G Oldroyd
In patients with coronary heart disease, revascularization can improve symptoms and in certain high-risk subgroups may improve prognosis. Coronary angiography provides anatomical information and the physiological significance of a stenosis can be determined using fractional flow reserve (FFR). Decisions on the need for and mode of revascularization can be optimized using FFR, however this involves administering adenosine to induce hyperemia. Generally, this test is well tolerated, but in some healthcare systems adenosine is either not licensed, unavailable, or expensive, limiting the use of FFR-guided management...
September 28, 2017: Circulation
https://www.readbyqxmd.com/read/28971799/human-and-nonhuman-primate-meninges-harbor-lymphatic-vessels-that-can-be-visualized-noninvasively-by-mri
#7
Martina Absinta, Seung-Kwon Ha, Govind Nair, Pascal Sati, Nicholas J Luciano, Maryknoll Palisoc, Antoine Louveau, Kareem A Zaghloul, Stefania Pittaluga, Jonathan Kipnis, Daniel S Reich
Here, we report the existence of meningeal lymphatic vessels in human and nonhuman primates (common marmoset monkeys) and the feasibility of noninvasively imaging and mapping them in vivo with high-resolution, clinical MRI. On T2-FLAIR and T1-weighted black-blood imaging, lymphatic vessels enhance with gadobutrol, a gadolinium-based contrast agent with high propensity to extravasate across a permeable capillary endothelial barrier, but not with gadofosveset, a blood-pool contrast agent. The topography of these vessels, running alongside dural venous sinuses, recapitulates the meningeal lymphatic system of rodents...
October 3, 2017: ELife
https://www.readbyqxmd.com/read/28969854/mri-in-otology-applications-in-cholesteatoma-and-m%C3%A3-ni%C3%A3-re-s-disease
#8
REVIEW
R K Lingam, S E J Connor, J W Casselman, T Beale
Imaging of middle-ear cholesteatoma with diffusion-weighted imaging (DWI) magnetic resonance imaging (MRI), and inner-ear endolymphatic hydrops (in Ménière's disease) with post-gadolinium high-resolution MRI, are reviewed. DWI MRI provides for a more specific diagnosis of tympano-mastoid cholesteatoma. There is an established and increasing role of DWI MRI in detecting both primary and postoperative cholesteatoma, localising disease, and planning surgery. The contemporary diagnostic accuracy of DWI is reviewed, pitfalls in interpretation are described, and potential future developments are highlighted...
September 29, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28966303/appearance-of-the-organum-vasculosum-of-the-lamina-terminalis-on-contrast-enhanced-mr-imaging
#9
Shinji Naganawa, Toshiaki Taoka, Hisashi Kawai, Masahiro Yamazaki, Kojiro Suzuki
PURPOSE: Circumventricular organs (CVOs) lack a blood brain barrier and are also called "brain windows". Among CVOs, the organum vasculosum of the lamina terminalis (OVLT) is an osmotic regulator involved in the release of vasopressin. In a previous study of healthy subjects, it was reported that contrast enhancement in the OVLT can be recognized in only 34% of 3 Tesla thin slice contrast-enhanced T1-weighted images. The purpose of this study was to evaluate the leakage of gadolinium contrast from the OVLT in healthy subjects using heavily T2-weighted three dimensional-fluid attenuated inversion recovery (3D-FLAIR) (HF) imaging...
September 29, 2017: Magnetic Resonance in Medical Sciences: MRMS
https://www.readbyqxmd.com/read/28957339/focal-t2-and-flair-hyperintensities-within-the-infarcted-area-a-suitable-marker-for-patient-selection-for-treatment
#10
Julia Meisterernst, Pascal P Klinger-Gratz, Lars Leidolt, Matthias F Lang, Gerhard Schroth, Pasquale Mordasini, Mirjam R Heldner, Marie-Luise Mono, Rebekka Kurmann, Monika Buehlmann, Urs Fischer, Marcel Arnold, Jan Gralla, Heinrich P Mattle, Marwan El-Koussy, Simon Jung
BACKGROUND AND PURPOSE: Some authors use FLAIR imaging to select patients for stroke treatment. However, the effect of hyperintensity on FLAIR images on outcome and bleeding has been addressed in only few studies with conflicting results. METHODS: 466 patients with anterior circulation strokes were included in this study. They all were examined with MRI before intravenous or endovascular treatment. Baseline data and 3 months outcome were recorded prospectively. Focal T2 and FLAIR hyperintensities within the ischemic lesion were evaluated by two raters, and the PROACT II classification was applied to assess bleeding complications on follow up imaging...
2017: PloS One
https://www.readbyqxmd.com/read/28954003/adherence-to-bclc-recommendations-for-the-treatment-of-hepatocellular-carcinoma-impact-on-survival-according-to-stage
#11
Luciana Kikuchi, Aline Lopes Chagas, Regiane S S M Alencar, Claudia Tani, Marcio A Diniz, Luiz A C D'Albuquerque, Flair José Carrilho
OBJECTIVES: This study sought to assess the adherence of newly diagnosed hepatocellular carcinoma patients to the Barcelona Clinic Liver Cancer system treatment guidelines and to examine the impact of adherence on the survival of patients in different stages of the disease. METHODS: This study included all patients referred for the treatment of hepatocellular carcinoma between 2010 and 2012. Patients (n=364) were classified according to the Barcelona Clinic Liver Cancer guidelines...
August 2017: Clinics
https://www.readbyqxmd.com/read/28948373/evaluation-of-endolymphatic-hydrops-using-3-t-mri-after-intravenous-gadolinium-injection
#12
Takao Imai, Atsuhiko Uno, Tadashi Kitahara, Tomoko Okumura, Arata Horii, Yumi Ohta, Takashi Sato, Suzuyo Okazaki, Takefumi Kamakura, Yoshiyuki Ozono, Yoshiyuki Watanabe, Yukiko Hanada, Ryusuke Imai, Kazuya Ohata, Hidenori Inohara
Aim of this work is to establish evaluation criteria for identifying endolymphatic hydrops in the vestibule and cochlea using a magnetic resonance imaging (MRI) scanner. This is a retrospective diagnostic study. We evaluated 70 ears of 35 unilateral Ménière's disease patients. We performed 3-T MRI 4 h after intravenous gadolinium injection. Otologists manually traced the outline of vestibule, cochlea, and endolymphatic space of the vestibule and cochlea on two-dimensional fluid-attenuated inversion-recovery (2D-FLAIR) images...
September 25, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28947980/added-value-of-diffusion-weighted-imaging-in-pediatric-central-nervous-system-embryonal-tumors-surveillance
#13
Giovanni Morana, Cesar Augusto Alves, Domenico Tortora, Mariasavina Severino, Paolo Nozza, Armando Cama, Marcello Ravegnani, Gabriella D'Apolito, Alessandro Raso, Claudia Milanaccio, Claudia da Costa Leite, Maria Luisa Garrè, Andrea Rossi
Diffusion weighted imaging (DWI) has an established role in primary CNS embryonal tumor (ET) characterization; however, its diagnostic utility in detecting relapse has never been determined. We aimed to compare DWI and conventional MRI sensitivity in CNS ET recurrence detection, and to evaluate the DWI properties of contrast-enhancing radiation induced lesions (RIL). Fifty-six patients with CNS ET (25 with disease relapse, 6 with RIL and 25 with neither disease relapse nor RIL) were retrospectively evaluated with DWI, conventional MRI (including both T2/FLAIR and post-contrast images), or contrast-enhanced MR imaging (CE-MRI) alone...
September 1, 2017: Oncotarget
https://www.readbyqxmd.com/read/28945908/assessment-of-optimal-imaging-protocol-sequences-after-laser-induced-thermal-therapy-for-intracranial-tumors
#14
Anthony J Parisi, Sri Hari Sundararajan, Rahul Garg, Eric L Hargreaves, Nitesh V Patel, Shabbar F Danish
BACKGROUND: Magnetic resonance-guided laser-induced thermal therapy (MRgLITT) is a novel, minimally invasive method currently being used to treat a wide range of intracranial pathologies. No accepted guidelines exist on what the appropriate magnetic resonance imaging (MRI) sequences are for evaluating short-term postablation changes, especially when patients are not able to receive gadolinium. OBJECTIVE: To evaluate which MRI sequences provide the greatest inter-rater reliability and least amount of variability in assessment of ablation volume after MRgLITT for intracranial neoplasms...
August 28, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28945871/tumor-volume-assessment-in-low-grade-gliomas-a-comparison-of-preoperative-magnetic-resonance-imaging-to-coregistered-intraoperative-3-dimensional-ultrasound-recordings
#15
Bodil Karoline Ravn Munkvold, Hans Kristian Bø, Asgeir Store Jakola, Ingerid Reinertsen, Erik Magnus Berntsen, Geirmund Unsgård, Sverre Helge Torp, Ole Solheim
BACKGROUND: Image guidance based on magnetic resonance imaging (MRI) and/or ultrasound (US) is widely used to aid decision making in glioma surgery, but tumor delineation based on these 2 modalities does not always correspond. OBJECTIVE: To analyze volumes of diffuse low-grade gliomas (LGGs) based on preoperative 3-D FLAIR MRIs compared to intraoperative 3-D US image recordings to quantitatively assess potential discrepancies between the 2 imaging modalities. METHODS: Twenty-three patients with supratentorial WHO grade II gliomas undergoing primary surgery guided by neuronavigation based on preoperative FLAIR MRI and navigated 3-D US were included...
August 10, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28944575/seven-tesla-magnetization-transfer-imaging-to-detect-multiple-sclerosis-white-matter-lesions
#16
I-Jun Chou, Su-Yin Lim, Radu Tanasescu, Ali Al-Radaideh, Olivier E Mougin, Christopher R Tench, William P Whitehouse, Penny A Gowland, Cris S Constantinescu
BACKGROUND AND PURPOSE: Fluid-attenuated inversion recovery (FLAIR) imaging at 3 Tesla (T) field strength is the most sensitive modality for detecting white matter lesions in multiple sclerosis. While 7T FLAIR is effective in detecting cortical lesions, it has not been fully optimized for visualization of white matter lesions and thus has not been used for delineating lesions in quantitative magnetic resonance imaging (MRI) studies of the normal appearing white matter in multiple sclerosis...
September 25, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28943053/our-experience-with-500-patients-with-benign-paroxysmal-positional-vertigo-reexploring-aetiology-and-reevaluating-mri-investigation
#17
Fei Tan, Constantin Bartels, Rory McConn Walsh
OBJECTIVE: To explore the aetiology of and to evaluate the importance of MRI investigation on the posterior semicircular canal benign paroxysmal positional vertigo in an Irish population. METHODS: A retrospective observational study of 500 patients with posterior semicircular canal benign paroxysmal positional vertigo, diagnosed and treated by the senior author over a 10-year period. Most patients underwent an MRI brain and inner ear, following the same scan protocol...
September 21, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28936607/time-of-flight-mr-angiography-in-cerebral-venous-sinus-thrombosis
#18
Dimitri Renard, Emmanuelle Le Bars, Caroline Arquizan, Nicolas Gaillard, Nicolas Menjot de Champfleur, Isabelle Mourand
Recently, time-of-flight (TOF) and gadolinium-enhanced MR angiography (MRA) imaging have been used to demonstrate subacute intramural hematoma in cervical artery dissection and to detect intraplaque haemorrhage. Our aim was to perform an exploratory study to analyse if venous thrombus-related signal changes (potentially showing iso- or hyperintensity) in cerebral venous sinus thrombosis (CVST) could be observed on 3D-TOF MRA imaging. We analysed retrospectively MRIs of CVST patients in whom both contrast-enhanced MR venography (CEMRV) and 3D-TOF sequences were performed in the acute/subacute phase (i...
September 21, 2017: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/28918752/correlation-of-csf-flow-using-phase-contrast-mri-with-ventriculomegaly-and-csf-opening-pressure-in-mucopolysaccharidoses
#19
Amauri Dalla Corte, Carolina F M de Souza, Maurício Anés, Fabio K Maeda, Armelle Lokossou, Leonardo M Vedolin, Maria Gabriela Longo, Monica M Ferreira, Solanger G P Perrone, Olivier Balédent, Roberto Giugliani
BACKGROUND: Very little is known about the incidence and prevalence of hydrocephalus in patients with mucopolysaccharidoses (MPS). The biggest challenge is to distinguish communicating hydrocephalus from ventricular dilatation secondary to brain atrophy, because both conditions share common clinical and neuroradiological features. The main purpose of this study is to assess the relationship between ventriculomegaly, brain and cerebrospinal fluid (CSF) volumes, aqueductal and cervical CSF flows, and CSF opening pressure in MPS patients, and to provide potential biomarkers for abnormal CSF circulation...
September 18, 2017: Fluids and Barriers of the CNS
https://www.readbyqxmd.com/read/28903444/early-tumour-shrinkage-as-a-survival-predictor-in-patients-with-recurrent-glioblastoma-treated-with-bevacizumab-in-the-avareg-randomized-phase-ii-study
#20
Alba A Brandes, Gaetano Finocchiaro, Vittorina Zagonel, Michele Reni, Alessandra Fabi, Claudia Caserta, Alicia Tosoni, Marica Eoli, Giuseppe Lombardi, Matteo Clavarezza, Alexandro Paccapelo, Stefania Bartolini, Luigi Cirillo, Raffaele Agati, Enrico Franceschi
BACKGROUND: Disease assessment for recurrent glioblastoma (GBM) represents a challenge, especially with the use of antiangiogenic agents. Moreover, validated neuroradiological predictors of outcome are lacking. Recently, the concept of early tumor shrinkage (ETS) has been developed to better assess the ability of treatments in determining a rapid and remarkable tumor response. The aim of the study was to evaluate the role of ETS in predicting survival of GBM patients treated with BEV...
August 15, 2017: Oncotarget
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