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https://www.readbyqxmd.com/read/29244126/silent-cerebral-small-vessel-disease-twice-as-prevalent-in-middle-aged-well-controlled-cart-treated-hiv-infected-individuals-than-hiv-uninfected-individuals
#1
Antoine Moulignier, Julien Savatovsky, Lambert Assoumou, François-Xavier Lescure, Cédric Lamirel, Ophelia Godin, Nadia Valin, Roland Tubiana, Ana Canestri, Pascal Roux, Jean-Claude Sadik, Laurence Salomon, Marie Abrivard, Christine Katlama, Yazdan Yazdanpanah, Gilles Pialoux, Pierre-Marie Girard, Dominique Costagliola
Background: Silent cerebral small-vessel disease (CSVD) is defined as white matter hyperintensities, silent brain infarction or microbleeds. CSVD is responsible for future vascular events, cognitive impairment, frailty and shorter survival. CSVD prevalence among middle-aged persons living with well-controlled HIV infection (PLHIVs) is unknown. Methods: ANRS EP51 MicroBREAK (NCT02082574) is a cross-sectional study with prospective enrollment of treated PLHIVs, ≥50 years old with viral load controlled for ≥12 months, and frequency age- and sex-matched HIV-uninfected controls (HUCs)...
December 13, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29235194/dual-sensitivity-multiple-sclerosis-lesion-and-csf-segmentation-for-multichannel-3t-brain-mri
#2
Dominik S Meier, Charles R G Guttmann, Subhash Tummala, Nicola Moscufo, Michele Cavallari, Shahamat Tauhid, Rohit Bakshi, Howard L Weiner
BACKGROUND AND PURPOSE: A pipeline for fully automated segmentation of 3T brain MRI scans in multiple sclerosis (MS) is presented. This 3T morphometry (3TM) pipeline provides indicators of MS disease progression from multichannel datasets with high-resolution 3-dimensional T1-weighted, T2-weighted, and fluid-attenuated inversion-recovery (FLAIR) contrast. 3TM segments white (WM) and gray matter (GM) and cerebrospinal fluid (CSF) to assess atrophy and provides WM lesion (WML) volume. METHODS: To address nonuniform distribution of noise/contrast (eg, posterior fossa in 3D-FLAIR) of 3T magnetic resonance imaging, the method employs dual sensitivity (different sensitivities for lesion detection in predefined regions)...
December 13, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29233600/noise-reduction-in-flair2-images-using-total-generalized-variation-gaussian-and-wiener-filtering
#3
René Schranzer, Alexander Rauscher, Evelin Haimburger, Kristian Bredies, Gernot Reishofer, Günther Grabner
PURPOSE: Multiplication of FLAIR and T2-weighted MRI scans results in images (called FLAIR2) with an improved contrast-to-noise ratio (CNR) for multiple sclerosis (MS) lesions but with a reduced signal-to-noise ratio (SNR). Denoising of these images may therefore further improve FLAIR2 image quality. The purpose of this work is to present a systematic investigation of FLAIR2 image denoising methods using Gaussian, Wiener and Total Generalized Variation (TGV) filtering approaches. MATERIALS AND METHODS: T2-weighted and FLAIR data of four MS patients were used...
December 9, 2017: Zeitschrift Für Medizinische Physik
https://www.readbyqxmd.com/read/29229341/diagnostic-performance-of-increased-signal-intensity-within-the-resection-cavity-on-fluid-attenuated-inversion-recovery-sequences-for-detection-of-progression-in-patients-with-glioma
#4
REVIEW
Jing Zhang, Yanlin Song, Min He, Qingqing Ren, Yunhui Zeng, Zhiyong Liu, Hao Liu, Jianguo Xu
OBJECT: The aim of this study was to systematically evaluate the diagnostic performance of increased signal intensity within the resection cavity on fluid-attenuated inversion recovery (FLAIR) sequences for detection of progression in patients with glioma through performing a meta-analysis. METHODS: PubMed, Web of Science, EMBASE, Cochrane Library and China National Knowledge Infrastructure were searched for potentially relevant literature. The study characteristics and relevant data were extracted...
December 8, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29227452/high-resolution-three-dimensional-delayed-contrast-mri-detects-endolymphatic-hydrops-in-patients-with-vertigo-and-vestibular-schwannoma
#5
Roxana Moayer, Gail P Ishiyama, Stellios Karnezis, Ali R Sepahdari, Akira Ishiyama
OBJECTIVE: Advances in high resolution magnetic resonance imaging (MRI) have enabled the detection of endolymphatic hydrops (EH), a pathological ballooning of the endolymphatic fluid system, known to be associated with Menière's disease. When a patient has a known diagnosis of vestibular schwannoma and develops recurrent episodic vertigo spells, many surgeons recommend surgical intervention, attributing the vestibular symptoms to the vestibular schwannoma. The aim of this study is to evaluate the clinical outcome in patients with vestibular schwannoma and EH, treated medically, for recurrent spells of vertigo...
January 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29220731/quantitative-texture-analysis-in-the-prediction-of-idh-status-in-low-grade-gliomas
#6
Asgeir Store Jakola, Yi-Hua Zhang, Anne J Skjulsvik, Ole Solheim, Hans Kristian Bø, Erik Magnus Berntsen, Ingerid Reinertsen, Sasha Gulati, Petter Förander, Torkel B Brismar
OBJECTIVES: Molecular markers provide valuable information about treatment response and prognosis in patients with low-grade gliomas (LGG). In order to make this important information available prior to surgery the aim of this study was to explore if molecular status in LGG can be discriminated by preoperative magnetic resonance imaging (MRI). PATIENTS AND METHODS: All patients with histopathologically confirmed LGG with available molecular status who had undergone a preoperative standard clinical MRI protocol using a 3T Siemens Skyra scanner during 2008-2015 were retrospectively identified...
December 5, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29219268/-application-of-susceptibility-weighted-imaging-in-the-identification-of-hemorrhagic-diffuse-axonal-injury
#7
W Li
OBJECTIVES: To explore the application value of susceptibility weighted imaging (SWI) in the forensic identification of hemorrhagic diffuse axonal injury (DAI). METHODS: The forensic identification materials of 20 DAI cases were analyzed retrospectively. The sequence image materials of T1WI, T2WI, diffusion weighted imaging (DWI), fluid attenuated inversion recovery (FLAIR) and susceptibility weighted imaging (SWI) were analyzed statistically...
August 2017: Fa Yi Xue za Zhi
https://www.readbyqxmd.com/read/29204838/volumetric-response-of-progressing-post-srs-lesions-treated-with-laser-interstitial-thermal-therapy
#8
Vivek B Beechar, Sujit S Prabhu, Dhiego Bastos, Jeffrey S Weinberg, R Jason Stafford, David Fuentes, Kenneth R Hess, Ganesh Rao
We analyzed volumetric response of metastatic brain tumors that progressed despite treatment with stereotactic radiosurgery (SRS) after treatment with laser interstitial thermal therapy (LITT). We retrospectively reviewed consecutive patients treated from 1/2012 to 10/2015 with LITT for metastatic brain tumors demonstrating progression after SRS. Volumes were quantified using MRI with contrast-enhanced T1-weighted (T1W) and fluid-attenuated inversion recovery (FLAIR). Fifty lesions from 36 patients were studied...
December 4, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/29204189/reversible-splenial-lesion-syndrome-resles-coinciding-with-cerebral-venous-thrombosis-a-report-of-two-cases
#9
REVIEW
Jingyi Liu, Dacheng Liu, Bo Yang, Jing Yan, Yuehua Pu, Jing Zhang, Miao Wen, Zhonghua Yang, Liping Liu
A total of two postpartum women with no noteworthy medical history presented with persistent headache. Brain magnetic resonance imaging (MRI) of both revealed extensive cerebral venous thrombosis, concurrently with abnormal signals of the splenium of the corpus callosum (SCC): The splenium appeared hyperintense on T2-weighted sequences, fluid-attenuated inversion recovery (FLAIR), and diffusion-weighted imaging (DWI) imaging, and hypointense on T1 sequences and apparent diffusion coefficient (ADC) map. The patients were given thrombolytic therapy...
December 2017: Therapeutic Advances in Neurological Disorders
https://www.readbyqxmd.com/read/29204012/use-of-preoperative-ependymal-enhancement-on-magnetic-resonance-imaging-brain-as-a-marker-of-grade-of-glioma
#10
Sumit Sharma, Shashi Kant Jain, Virendra Deo Sinha
Objectives: Neural stem cells within the subventricular zone (SVZ) are thought to be responsible for the origin and the heterogeneous nature of the gliomas. The relationship of the gliomas to the SVZ can be appreciated as ependymal enhancement on contrast magnetic resonance imaging (MRI). This study evaluates the rate of ependymal enhancement and its association with the histopathological grade of gliomas. Patients and Methods: Seventy-five patients with radiological features of glioma were recruited...
October 2017: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/29200014/increased-delay-between-gadolinium-chelate-administration-and-t1-weighted-magnetic-resonance-imaging-acquisition-increases-contrast-enhancing-tumor-volumes-and-t1-intensities-in-brain-tumor-patients
#11
Paula L Piechotta, David Bonekamp, Martin Sill, Antje Wick, Wolfgang Wick, Martin Bendszus, Philipp Kickingereder
OBJECTIVES: The aim of this study was to evaluate the impact of delayed T1-weighted (T1-w) MRI acquisition after gadolinium chelate administration on brain tumor volumes and T1-w intensities. MATERIALS AND METHODS: Fifty-five patients with histologically confirmed, contrast-enhancing intra-axial brain tumors were analyzed in this prospective test-retest study. Patients underwent 2 consecutive 3 T MRI scans (separated by a 1-minute break) during routine follow-up with contrast-enhanced T1 (ceT1-w), T2, and FLAIR acquisition...
November 29, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/29193849/apparent-transverse-relaxation-r2%C3%A2-on-mri-as-a-method-to-differentiate-treatment-effect-pseudoprogression-versus-progressive-disease-in-chemoradiation-for-malignant-glioma
#12
Jean-Guy Belliveau, Glenn S Bauman, David Macdonald, Maria Macdonald, L Martyn Klassen, Ravi S Menon
INTRODUCTION: Pseudoprogression (psPD) is a transient post-treatment imaging change that is commonly seen when treating glioma with chemotherapy and radiation. The use of apparent transverse relaxation rate (R2∗), which is calculated from a contrast-free multi-echo gradient echo Magnetic Resonance Imaging (MRI) sequence, may allow for quantitative identification of patients with suspected psPD. METHODS: We acquired a multi-echo gradient echo sequence using a 3T-Siemens Prisma MRI...
November 30, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29191871/mr-imaging-characteristics-associate-with-tumor-associated-macrophages-in-glioblastoma-and-provide-an-improved-signature-for-survival-prognostication
#13
J Zhou, M V Reddy, B K J Wilson, D A Blair, A Taha, C M Frampton, R A Eiholzer, P Y C Gan, F Ziad, Z Thotathil, S Kirs, N A Hung, J A Royds, T L Slatter
BACKGROUND AND PURPOSE: In glioblastoma, tumor-associated macrophages have tumor-promoting properties. This study determined whether routine MR imaging features could predict molecular subtypes of glioblastoma that differ in the content of tumor-associated macrophages. MATERIALS AND METHODS: Seven internally derived MR imaging features were assessed in 180 patients, and 25 features from the Visually AcceSAble Rembrandt Images feature set were assessed in 164 patients...
November 30, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29191851/dwi-aspects-diffusion-weighted-imaging-alberta-stroke-program-early-computed-tomography-scores-and-dwi-flair-diffusion-weighted-imaging-fluid-attenuated-inversion-recovery-mismatch-in-thrombectomy-candidates-an-intrarater-and-interrater-agreement-study
#14
Robert Fahed, Augustin Lecler, Candice Sabben, Naim Khoury, Célina Ducroux, Vanessa Chalumeau, Daniele Botta, Erwah Kalsoum, William Boisseau, Loïc Duron, Dominique Cabral, Patricia Koskas, Azzedine Benaïssa, Hasmik Koulakian, Michael Obadia, Benjamin Maïer, David Weisenburger-Lile, Bertrand Lapergue, Adrien Wang, Hocine Redjem, Gabriele Ciccio, Stanislas Smajda, Jean-Philippe Desilles, Mikaël Mazighi, Malek Ben Maacha, Inès Akkari, Kevin Zuber, Raphaël Blanc, Jean Raymond, Michel Piotin
BACKGROUND AND PURPOSE: We aimed to study the intrarater and interrater agreement of clinicians attributing DWI-ASPECTS (Diffusion-Weighted Imaging-Alberta Stroke Program Early Computed Tomography Scores) and DWI-FLAIR (Diffusion-Weighted Imaging-Fluid Attenuated Inversion Recovery) mismatch in patients with acute ischemic stroke referred for mechanical thrombectomy. METHODS: Eighteen raters independently scored anonymized magnetic resonance imaging scans of 30 participants from a multicentre thrombectomy trial, in 2 different reading sessions...
November 30, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29190679/infarct-morphology-assessment-in-patients-with-carotid-artery-middle-cerebral-artery-occlusion-using-fast-fluid-attenuated-inversion-recovery-flair-vascular-hyperintensity-fvh
#15
Deng-Yue Zhai, Shuang-Gen Zhu, Wei Zhang, Xue Li, You-Ling Zhu
We aim to evaluate the value of fast fluid-attenuated inversion recovery (FLAIR) vascular hyperintensity (FVH) in assessing infarct morphology in patients with symptomatic internal carotid artery (ICA) or middle cerebral artery (MCA) occlusions. Magnetic resonance (MR) diffusion-weighted imaging (DWI) FLAIR sequences, and carotid/cerebral magnetic resonance angiography of 102 patients with symptomatic ICA or MCA occlusions were evaluated. The location and score of FVH were determined using Olindo's method; patients were classified as having Low or High FVHs based on FVH score, and either Distal or Proximal FVH based on FVH location...
2017: PloS One
https://www.readbyqxmd.com/read/29187687/-symmetrical-lesions-of-the-cerebral-peduncles-and-internal-capsules-on-mri-in-a-patient-with-extranodal-nk-t-cell-lymphoma
#16
Yuko Takeuchi, Tomotsugu Kaga, Miho Ieda, Yumi Kojima, Jun Ochiai, Chiyuki Mabuchi
A 72-year-old man was admitted to our hospital because of subacute progressive consciousness disturbance. FLAIR images showed diffuse high intensity areas in the bilateral thalamus, basal ganglia, and white matter. Chest CT revealed a mass in the right lung. The patient was diagnosed with extranodal natural killer/T cell lymphoma (ENKL) according to the results of a biopsy of the right pulmonary mass. The FLAIR images showed diffuse white matter lesions, without a mass such as lymphomatosis cerebri. On diffusion-weighted images, symmetrical high-intensity lesions of the cerebral peduncle and the internal capsule suggested high-density lymphoma cells around neurons...
November 28, 2017: Rinshō Shinkeigaku, Clinical Neurology
https://www.readbyqxmd.com/read/29181872/validation-of-t1w-based-segmentations-of-white-matter-hyperintensity-volumes-in-large-scale-datasets-of-aging
#17
Mahsa Dadar, Josefina Maranzano, Simon Ducharme, Owen T Carmichael, Charles Decarli, D Louis Collins
INTRODUCTION: Fluid-attenuated Inversion Recovery (FLAIR) and dual T2w and proton density (PD) magnetic resonance images (MRIs) are considered to be the optimum sequences for detecting white matter hyperintensities (WMHs) in aging and Alzheimer's disease populations. However, many existing large multisite studies forgo their acquisition in favor of other MRI sequences due to economic and time constraints. METHODS: In this article, we have investigated whether FLAIR and T2w/PD sequences are necessary to detect WMHs in Alzheimer's and aging studies, compared to using only T1w images...
November 27, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/29180935/atypical-bilateral-cerebellopontine-angle-medulloblastoma-differential-diagnosis-immunohistochemical-features-and-radiological-presentation
#18
Kelvin M Piña Batista, Sayoa Alvarez de Eulate-Beramendi, María Rico, Victor Rodrigo, Yordy E Batista Batista, Kenia Y Alvarez Reyes
Medulloblastoma (MB) is a highly aggressive soft tissue neoplasm, classified as a primitive neuroectodermal tumor. It is the most common posterior fossa tumor in children, but occurs rarely in adults. MB accounts for approximately 20% of all primary central nervous system (CNS) tumors of childhood, while its incidence is around 1% of adult brain tumors. Most often it occurs in the cerebellum. We report a case of multicentric MB involving the bilateral cerebellopontine angle (CPA) and right cerebellar hemisphere...
2017: Contemporary Oncology Współczesna Onkologia
https://www.readbyqxmd.com/read/29178838/hepatitis-c-virus-eradication-improves-immediate-and-delayed-episodic-memory-in-patients-treated-with-interferon-and-ribavirin
#19
Mary Ellen Dias Barbosa, Ana Luiza Zaninotto, Daniel Ferraz de Campos Mazo, Mario Guimarães Pessoa, Cláudia Pinto Marques Souza de Oliveira, Flair José Carrilho, Alberto Queiroz Farias
BACKGROUND: Chronic hepatitis C virus (HCV) infection is associated with impairment of cognitive function and mood disorders. Our aim was to evaluate the impact of sustained virological response (SVR) on cognitive function and mood disorders. METHOD: A prospective exploratory one arm study was conducted. Adult clinically compensated HVC patients were consecutively recruited before treatment with interferon and ribavirin for 24 to 48 weeks, according to HCV genotype...
November 25, 2017: BMC Gastroenterology
https://www.readbyqxmd.com/read/29171859/acute-acalculous-cholecystitis-during-zika-virus-infection-in-an-immunocompromised-patient
#20
Suzane Kioko Ono, Leda Bassit, Victor Van Vaisberg, Venâncio Avancini Ferreira Alves, Elia G Caldini, Brian D Herman, Reed Shabman, Nadia B Fedorova, Denise Paranaguá-Vezozzo, Caroline Torres Sampaio, Rafael Bandeira Lages, Débora Terrabuio, Wellington Andraus, Raymond F Schinazi, Flair José Carrilho
No abstract text is available yet for this article.
November 24, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
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